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152 results on '"Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS)"'

1. Chronic bronchitis without airflow obstruction, asthma and rhinitis are differently associated with cardiovascular risk factors and diseases

Author: Pietro Pirina, Pierpaolo Marchetti, Giulia Squillacioti, Elia Piccinno, Giuseppe Verlato, Salvatore Battaglia, Amelia Grosso, Alessandro Marcon, Giancarlo Pesce, Marcello Ferrari, Lucia Cazzoletti, Leonardo Antonicelli, Ferrari M., Piccinno E., Marcon A., Marchetti P., Cazzoletti L., Pirina P., Battaglia S., Grosso A., Squillacioti G., Antonicelli L., Verlato G., Pesce G., Bodescot, Myriam, Unit of Respiratory Medicine [Vérone, Italie], Department of Diagnostics and Public Health [Verona] (UNIVR | DDSP), Università degli studi di Verona = University of Verona (UNIVR)-Università degli studi di Verona = University of Verona (UNIVR), Unit of Epidemiology and Medical Statistics [Vérone, Italie], Department of Diagnostics and Public Health [Vérone, Italie], Unità Operativa di Pneumologia [Sassari, Italie], Dipartimento di Scienze Mediche, Chirurgiche e Sperimentali [Sassari, Italie], Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS)-Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Dipartimento Universitario di Promozione della Salute, Materno Infantile, Medicina Interna e Specialistica di Eccellenza 'G. D'Alessandro' [Palerme, Italie] (PROMISE), Università degli studi di Palermo - University of Palermo, Division of Respiratory Diseases [Pavie, Italie], IRCCS 'San Matteo' Hospital Foundation [Pavie, Italie], Università degli Studi di Pavia = University of Pavia (UNIPV)-Università degli Studi di Pavia = University of Pavia (UNIPV), Department of Public Health and Pediatrics [Turin, Italie], Università degli studi di Torino = University of Turin (UNITO), Allergy Unit [Ancône, Italie], Department of Internal Medicine [Ancône, Italie], Azienda Ospedaliero-Universitaria Ospedali Riuniti [Ancône, Italie]-Azienda Ospedaliero-Universitaria Ospedali Riuniti [Ancône, Italie], Epidemiology of Allergic and Respiratory Diseases Department [iPlesp] (EPAR), Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), The GEIRD study was funded by the Cariverona foundation, the Italian Ministry of Health, Chiesi Farmaceutici SpA, and the Agenzia Italiana del Farmaco (AIFA)., University of Verona (UNIVR)-University of Verona (UNIVR), Università degli Studi di Sassari [Sassari] (UNISS)-Università degli Studi di Sassari [Sassari] (UNISS), University of Pavia-University of Pavia, University of Turin, Epidemiology of Allergic and Respiratory Diseases Department [Paris] (EPAR), and Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM)
Subjects: Male, LUNG-DISEASE, Chronic bronchitis, Pulmonology, Epidemiology, Blood Pressure, Cardiovascular Medicine, 030204 cardiovascular system & hematology, Vascular Medicine, [SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract, Cohort Studies, Pulmonary Disease, Chronic Obstructive, 0302 clinical medicine, Risk Factors, Medicine and Health Sciences, Odds Ratio, chronic bronchiti, Lung, Rhinitis, Aged, 80 and over, education.field_of_study, Alcohol Consumption, Multidisciplinary, Heart, Middle Aged, Cardiovascular disease, CB, Respiratory Function Tests, 3. Good health, PREVALENCE, [SDV.MHEP.CSC] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Bronchitis, Chronic, ALLERGIC RHINITIS, INTERMITTENT CLAUDICATION, Cardiovascular Diseases, Hypertension, Bronchitis, Medicine, chronic bronchitis, Female, Anatomy, medicine.symptom, Research Article, Adult, medicine.medical_specialty, Science, Population, body mass index, Settore MED/10 - Malattie Dell'Apparato Respiratorio, DIAGNOSIS, elderly, chronic obstructive pulmonary disease, Young Adult, 03 medical and health sciences, Heart disorder, BMI, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Internal medicine, Confidence Intervals, medicine, Humans, COPD, CORONARY-HEART-DISEASE, education, Nutrition, Aged, Asthma, MYOCARDIAL-INFARCTION, MUCUS HYPERSECRETION, CIGARETTE-SMOKING, ATHEROSCLEROSIS, business.industry, Biology and Life Sciences, Odds ratio, Rhinology, asthma, medicine.disease, Intermittent claudication, Diet, Otorhinolaryngology, 030228 respiratory system, [SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie, Medical Risk Factors, Case-Control Studies, Relative risk, Nasal Diseases, Cardiovascular Anatomy, [SDV.MHEP.PSR] Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, business, BMI, body mass index, CB, chronic bronchitis, COPD, chronic obstructive pulmonary disease
Abstract: Background and objectives Cardiovascular and respiratory diseases can frequently coexist. Understanding their link may improve disease management. We aimed at assessing the associations of chronic bronchitis (CB), asthma and rhinitis with cardiovascular diseases and risk factors in the general population. Methods We used data collected in the Gene Environment Interactions in Respiratory Diseases study, an Italian multicentre, multicase-control study. Among 2463 participants (age 21–86, female 50%) who underwent standardized interviews, skin prick and lung function tests, we identified 254 cases of CB without airflow obstruction, 418 cases of asthma without CB, 959 cases of rhinitis alone, and 832 controls. The associations of respiratory diseases with reported cardiovascular risk factors (lifestyles, hypertension, dyslipidaemia), heart disorders (myocardial infarction, coronary thrombosis, angina, aorta or heart surgery) and intermittent claudication were estimated through relative risk ratios (RRR) by multinomial logistic regression models. Results Compared to controls, CB cases were more likely to be heavy smokers, alcohol consumers, physically inactive, and to suffer from hypertension or dyslipidaemia; rhinitis cases were less obese but more likely to have hypertension. Asthma was significantly associated with current smoking. After adjusting for cardiovascular risk factors, heart disorders were associated with CB (RRR[95%CI]: 1.58[1.12–2.22]) and rhinitis (1.35[0.98–1.85]) and intermittent claudication was associated with CB (3.43[2.52–4.67]), asthma (1.51[1.04–2.21]) and rhinitis (2.03[1.34–3.07]). Conclusions CB, asthma and rhinitis were associated with cardiovascular risk factors and diseases. In particular, CB shared with cardiovascular diseases almost all risk factors and was strongly associated with a higher risk of heart disorders and intermittent claudication.
Published: 2019

2. Search for dark-matter–Nucleon interactions via Migdal effect with DarkSide-50

Author: Agnes, P., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Ave, M., Back, H. O., Batignani, G., Biery, K., Bocci, V., Bonivento, W. M., Bottino, B., Bussino, S., Cadeddu, M., Cadoni, M., Calaprice, F., Caminata, A., Campos, M. D., Canci, N., Caravati, M., Cargioli, N., Cariello, M., Carlini, M., Cataudella, V., Cavalcante, P., Cavuoti, S., Chashin, S., Chepurnov, A., Cicalò, C., Covone, G., D’Angelo, D., Davini, S., De Candia, A., De Cecco, S., De Filippis, G., De Rosa, G., Derbin, A. V., Devoto, A., D’Incecco, M., Dionisi, C., Dordei, F., Downing, M., D’Urso, D., Fairbairn, M., Fiorillo, G., Franco, D., Gabriele, F., Galbiati, C., Ghiano, C., Giganti, C., Giovanetti, G. K., Goretti, A. M., Grilli di Cortona, G., Grobov, A., Gromov, M., Guan, M., Gulino, M., Hackett, B. R., Herner, K., Hessel, T., Hosseini, B., Hubaut, F., Hungerford, E. V., Ianni, An., Ippolito, V., Keeter, K., Kendziora, C. L., Kimura, M., Kochanek, I., Korablev, D., Korga, G., Kubankin, A., Kuss, M., La Commara, M., Lai, M., Li, X., Lissia, M., Longo, G., Lychagina, O., Machulin, I. N., Mapelli, L. P., Mari, S. M., Maricic, J., Messina, A., Milincic, R., Monroe, J., Morrocchi, M., Mougeot, X., Muratova, V. N., Musico, P., Nozdrina, A. O., Oleinik, A., Ortica, F., Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Pelczar, K., Pelliccia, N., Piacentini, S., Pocar, A., Poehlmann, D. M., Pordes, S., Poudel, S. S., Pralavorio, P., Price, D. D., Ragusa, F., Razeti, M., Razeto, A., Renshaw, A. L., Rescigno, M., Rode, J., Romani, A., Sablone, D., Samoylov, O., Sandford, E., Sands, W., Sanfilippo, S., Savarese, C., Schlitzer, B., Semenov, D. A., Shchagin, A., Sheshukov, A., Skorokhvatov, M. D., Smirnov, O., Sotnikov, A., Stracka, S., Suvorov, Y., Tartaglia, R., Testera, G., Tonazzo, A., Unzhakov, E. V., Vishneva, A., Vogelaar, R. B., Wada, M., Wang, H., Wang, Y., Westerdale, S., Wojcik, M. M., Xiao, X., Yang, C., Zuzel, G., Royal Holloway [University of London] (RHUL), Universidade de São Paulo = University of São Paulo (USP), Pacific Northwest National Laboratory (PNNL), University of South Dakota [Vermillion] (USD), Istituto Nazionale di Fisica Nucleare [Pisa] (INFN), Istituto Nazionale di Fisica Nucleare (INFN), Fermi National Accelerator Laboratory (Fermilab), Istituto Nazionale di Fisica Nucleare [Sezione di Roma 1] (INFN), Istituto Nazionale di Fisica Nucleare, Istituto Nazionale di Fisica Nucleare, Sezione di Cagliari (INFN, Sezione di Cagliari), Università degli studi di Genova = University of Genoa (UniGe), Università degli Studi di Cagliari = University of Cagliari (UniCa), Princeton University, Istituto Nazionale di Fisica Nucleare, Sezione di Genova (INFN, Sezione di Genova), King‘s College London, Laboratori Nazionali del Gran Sasso (LNGS), University of Naples Federico II = Università degli studi di Napoli Federico II, Virginia Tech [Blacksburg], D.V. Skobeltsyn Institute of Nuclear Physics (SINP), Lomonosov Moscow State University (MSU), Università degli Studi di Milano = University of Milan (UNIMI), Saint Petersburg Nuclear Physics Institute RAS, St Petersburg Nuclear Physics Institute, University of Massachusetts System (UMASS), Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Department of Physics, Princeton University (DPPU), INFN Frascati, Institute of Molecular Genetics of National Research Centre «Kurchatov Institute» [Moscow, Russia], Russian Academy of Sciences [Moscow] (RAS), Institute of High Energy Physics [Beijing] (IHEP), Chinese Academy of Sciences [Changchun Branch] (CAS), Università degli Studi di Enna ' KORE ' = Kore University of Enna, Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), University of Houston [Clear Lake], Black Hills State University, Nicolaus Copernicus Astronomical Cente (AstroCeNT), Joint Institute for Nuclear Research (JINR), University of Houston, Belgorod National Research University, University of California (UC), University of Hawai'i [Hilo], Laboratoire National Henri Becquerel (LNHB), Département Métrologie Instrumentation & Information (DM2I), Laboratoire d'Intégration des Systèmes et des Technologies (LIST (CEA)), Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Laboratoire d'Intégration des Systèmes et des Technologies (LIST (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Département d'instrumentation Numérique (DIN (CEA-LIST)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Università degli Studi di Perugia = University of Perugia (UNIPG), Istituto Nazionale di Fisica Nucleare, Sezione di Catania (INFN), Università degli studi di Catania = University of Catania (Unict), University of Massachusetts [Amherst] (UMass Amherst), University of California [Davis] (UC Davis), University of Manchester [Manchester], Università degli Studi di Roma Tor Vergata [Roma], Uniwersytet Jagielloński w Krakowie = Jagiellonian University (UJ), DarkSide Collaboration, Agnes, P., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Ave, M., Back, H. O., Batignani, G., Biery, K., Bocci, V., Bonivento, W. M., Bottino, B., Bussino, S., Cadeddu, M., Cadoni, M., Calaprice, F., Caminata, A., Campos, M. D., Canci, N., Caravati, M., Cargioli, N., Cariello, M., Carlini, M., Cataudella, V., Cavalcante, P., Cavuoti, S., Chashin, S., Chepurnov, A., Cicalò, C., Covone, G., D’Angelo, D., Davini, S., De Candia, A., De Cecco, S., De Filippis, G., De Rosa, G., Derbin, A. V., Devoto, A., D’Incecco, M., Dionisi, C., Dordei, F., Downing, M., D’Urso, D., Fairbairn, M., Fiorillo, G., Franco, D., Gabriele, F., Galbiati, C., Ghiano, C., Giganti, C., Giovanetti, G. K., Goretti, A. M., Grilli di Cortona, G., Grobov, A., Gromov, M., Guan, M., Gulino, M., Hackett, B. R., Herner, K., Hessel, T., Hosseini, B., Hubaut, F., Hungerford, E. V., Ianni, An., Ippolito, V., Keeter, K., Kendziora, C. L., Kimura, M., Kochanek, I., Korablev, D., Korga, G., Kubankin, A., Kuss, M., La Commara, M., Lai, M., Li, X., Lissia, M., Longo, G., Lychagina, O., Machulin, I. N., Mapelli, L. P., Mari, S. M., Maricic, J., Messina, A., Milincic, R., Monroe, J., Morrocchi, M., Mougeot, X., Muratova, V. N., Musico, P., Nozdrina, A. O., Oleinik, A., Ortica, F., Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Pelczar, K., Pelliccia, N., Piacentini, S., Pocar, A., Poehlmann, D. M., Pordes, S., Poudel, S. S., Pralavorio, P., Price, D. D., Ragusa, F., Razeti, M., Razeto, A., Renshaw, A. L., Rescigno, M., Rode, J., Romani, A., Sablone, D., Samoylov, O., Sandford, E., Sands, W., Sanfilippo, S., Savarese, C., Schlitzer, B., Semenov, D. A., Shchagin, A., Sheshukov, A., Skorokhvatov, M. D., Smirnov, O., Sotnikov, A., Stracka, S., Suvorov, Y., Tartaglia, R., Testera, G., Tonazzo, A., Unzhakov, E. V., Vishneva, A., Vogelaar, R. B., Wada, M., Wang, H., Wang, Y., Westerdale, S., Wojcik, M. M., Xiao, X., Yang, C., and Zuzel, G.
Subjects: instrumentation, electrons, General Physics and Astronomy, dark matter direct detection, dark matter mass, radioactivity, ionization, Dark matter, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], particle interaction, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], electron final state, ionizing radiation, signal processing, experimental results
Abstract: Dark matter elastic scattering off nuclei can result in the excitation and ionization of the recoiling atom through the so-called Migdal effect. The energy deposition from the ionization electron adds to the energy deposited by the recoiling nuclear system and allows for the detection of interactions of sub-GeV/c2 mass dark matter. We present new constraints for sub-GeV/c2 dark matter using the dual-phase liquid argon time projection chamber of the DarkSide-50 experiment with an exposure of (12 306±184) kg d. The analysis is based on the ionization signal alone and significantly enhances the sensitivity of DarkSide-50, enabling sensitivity to dark matter with masses down to 40 MeV/c2. Furthermore, it sets the most stringent upper limit on the spin independent dark matter nucleon cross section for masses below 3.6 GeV/c2.
Published: 2023

3. Search for low mass dark matter in DarkSide-50: the bayesian network approach

Author: Collaboration, The DarkSide-50, Agnes, P., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Ave, M., Back, H. O., Batignani, G., Biery, K., Bocci, V., Bonivento, W. M., Bottino, B., Bussino, S., Cadeddu, M., Cadoni, M., Calaprice, F., Caminata, A., Campos, M. D., Canci, N., Caravati, M., Cargioli, N., Cariello, M., Carlini, M., Cataudella, V., Cavalcante, P., Cavuoti, S., Chashin, S., Chepurnov, A., Cicalò, C., Covone, G., D'Angelo, D., Davini, S., De Candia, A., De Cecco, S., De Filippis, G., De Rosa, G., Derbin, A. V., Devoto, A., D'Incecco, M., Dionisi, C., Dordei, F., Downing, M., D'Urso, D., Fairbairn, M., Fiorillo, G., Franco, D., Gabriele, F., Galbiati, C., Ghiano, C., Giganti, C., Giovanetti, G. K., Goretti, A. M., di Cortona, G. Grilli, Grobov, A., Gromov, M., Guan, M., Gulino, M., Hackett, B. R., Herner, K., Hessel, T., Hosseini, B., Hubaut, F., Hungerford, E. V., Ianni, An., Ippolito, V., Keeter, K., Kendziora, C. L., Kimura, M., Kochanek, I., Korablev, D., Korga, G., Kubankin, A., Kuss, M., La Commara, M., Lai, M., Li, X., Lissia, M., Longo, G., Lychagina, O., Machulin, I. N., Mapelli, L. P., Mari, S. M., Maricic, J., Messina, A., Milincic, R., Monroe, J., Morrocchi, M., Mougeot, X., Muratova, V. N., Musico, P., Nozdrina, A. O., Oleinik, A., Ortica, F., Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Pelczar, K., Pelliccia, N., Piacentini, S., Pocar, A., Poehlmann, D. M., Pordes, S., Poudel, S. S., Pralavorio, P., Price, D. D., Ragusa, F., Razeti, M., Razeto, A., Renshaw, A. L., Rescigno, M., Rode, J., Romani, A., Sablone, D., Samoylov, O., Sandford, E., Sands, W., Sanfilippo, S., Savarese, C., Schlitzer, B., Semenov, D. A., Shchagin, A., Sheshukov, A., Skorokhvatov, M. D., Smirnov, O., Sotnikov, A., Stracka, S., Suvorov, Y., Tartaglia, R., Testera, G., Tonazzo, A., Unzhakov, E. V., Vishneva, A., Vogelaar, R. B., Wada, M., Wang, H., Wang, Y., Westerdale, S., Wojcik, M. M., Xiao, X., Yang, C., Zuzel, G., Royal Holloway [University of London] (RHUL), Escola Politecnica da Universidade de Sao Paulo [Sao Paulo], Pacific Northwest National Laboratory (PNNL), Augustana University, Istituto Nazionale di Fisica Nucleare [Pisa] (INFN), Istituto Nazionale di Fisica Nucleare (INFN), Fermi National Accelerator Laboratory (Fermilab), Istituto Nazionale di Fisica Nucleare [Sezione di Roma 1] (INFN), Istituto Nazionale di Fisica Nucleare, Istituto Nazionale di Fisica Nucleare, Sezione di Cagliari (INFN, Sezione di Cagliari), Università degli studi di Genova = University of Genoa (UniGe), Princeton University, Istituto Nazionale di Fisica Nucleare, Sezione di Genova (INFN, Sezione di Genova), King‘s College London, University of Naples Federico II = Università degli studi di Napoli Federico II, D.V. Skobeltsyn Institute of Nuclear Physics (SINP), Lomonosov Moscow State University (MSU), Università degli Studi di Milano = University of Milan (UNIMI), INFN Laboratori Nazionali del Gran Sasso, Istituto Nazionale di Fisica Nucleare, Sezione di Roma 3 (INFN, Sezione di Roma 3), University of Massachusetts [Amherst] (UMass Amherst), University of Massachusetts System (UMASS), Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), National Research Center 'Kurchatov Institute' (NRC KI), Moscow State Engineering Physics Institute (MEPhI), Institute of High Energy Physics [Beijing] (IHEP), Chinese Academy of Sciences [Changchun Branch] (CAS), INFN---Laboratori Nazionali del Sud (LNS), Via S. Sofia 62, 95123 Catania, Italy, Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), University of Houston, Black Hills State University, Nicolaus Copernicus Astronomical Cente (AstroCeNT), Joint Institute for Nuclear Research (JINR), Belgorod National Research University, 308015 Belgorod, Russia, Kurchatov NBIC Centre, National Research Centre, Kurchatov Institute, University of California (UC), University of Hawai'i [Honolulu] (UH), Laboratoire National Henri Becquerel (LNHB), Département Métrologie Instrumentation & Information (DM2I), Laboratoire d'Intégration des Systèmes et des Technologies (LIST (CEA)), Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Laboratoire d'Intégration des Systèmes et des Technologies (LIST (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Département d'instrumentation Numérique (DIN (CEA-LIST)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Università degli Studi di Perugia = University of Perugia (UNIPG), University of California [Davis] (UC Davis), Laboratori Nazionali del Sud (INFN), Uniwersytet Jagielloński w Krakowie = Jagiellonian University (UJ), University of Manchester [Manchester], Istituto Nazionale di Fisica Nucleare, Sezione di Milano (INFN), Virginia Tech [Blacksburg], Università degli Studi di Cagliari = University of Cagliari (UniCa), University of California [Riverside] (UC Riverside), the IN2P3-COPIN consortium (Grant No. 20-152), DarkSide-50 Collaboration, ANR-10-LABX-0023,UnivEarthS,Earth - Planets - Universe: observation, modeling, transfer(2010), ANR-18-IDEX-0001,Université de Paris,Université de Paris(2018), European Project: 952480,DarkWave, Agnes, P., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Ave, M., Back, H. O., Batignani, G., Biery, K., Bocci, V., Bonivento, W. M., Bottino, B., Bussino, S., Cadeddu, M., Cadoni, M., Calaprice, F., Caminata, A., Campos, M. D., Canci, N., Caravati, M., Cargioli, N., Cariello, M., Carlini, M., Cataudella, V., Cavalcante, P., Cavuoti, S., Chashin, S., Chepurnov, A., Cical??, C., Covone, G., D'Angelo, D., Davini, S., De Candia, A., De Cecco, S., De Filippis, G., De Rosa, G., Derbin, A. V., Devoto, A., D'Incecco, M., Dionisi, C., Dordei, F., Downing, M., D'Urso, D., Fairbairn, M., Fiorillo, G., Franco, D., Gabriele, F., Galbiati, C., Ghiano, C., Giganti, C., Giovanetti, G. K., Goretti, A. M., Grilli di Cortona, G., Grobov, A., Gromov, M., Guan, M., Gulino, M., Hackett, B. R., Herner, K., Hessel, T., Hosseini, B., Hubaut, F., Hungerford, E. V., Ianni, An., Ippolito, V., Keeter, K., Kendziora, C. L., Kimura, M., Kochanek, I., Korablev, D., Korga, G., Kubankin, A., Kuss, M., La Commara, M., Lai, M., Li, X., Lissia, M., Longo, G., Lychagina, O., Machulin, I. N., Mapelli, L. P., Mari, S. M., Maricic, J., Messina, A., Milincic, R., Monroe, J., Morrocchi, M., Mougeot, X., Muratova, V. N., Musico, P., Nozdrina, A. O., Oleinik, A., Ortica, F., Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Pelczar, K., Pelliccia, N., Piacentini, S., Pocar, A., Poehlmann, D. M., Pordes, S., Poudel, S. S., Pralavorio, P., Price, D. D., Ragusa, F., Razeti, M., Razeto, A., Renshaw, A. L., Rescigno, M., Rode, J., Romani, A., Sablone, D., Samoylov, O., Sandford, E., Sands, W., Sanfilippo, S., Savarese, C., Schlitzer, B., Semenov, D. A., Shchagin, A., Sheshukov, A., Skorokhvatov, M. D., Smirnov, O., Sotnikov, A., Stracka, S., Suvorov, Y., Tartaglia, R., Testera, G., Tonazzo, A., Unzhakov, E. V., Vishneva, A., Vogelaar, R. B., Wada, M., Wang, H., Wang, Y., Westerdale, S., Wojcik, M. M., Xiao, X., Yang, C., Zuzel, G., INFN Laboratori Nazionali del Gran Sasso, (INFN), Saint Petersburg Nuclear Physics Institute RAS, St Petersburg Nuclear Physics Institute, and DarkSide-50
Subjects: instrumentation, detector response, Cosmology and Nongalactic Astrophysics (astro-ph.CO), dark matter, mass, low, detector, Markov chain, FOS: Physical sciences, parametric, spectrum analysis, background, spectrum, Bayesian, dark matter, High Energy Physics - Experiment, High Energy Physics - Experiment (hep-ex), Monte Carlo, Markov chain, particle transport, network, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], Bayesian Networks, distribution function, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], signal processing, Monte Carlo, Statistical inference, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract: We present a novel approach for the search of dark matter in the DarkSide-50 experiment, relying on Bayesian Networks. This method incorporates the detector response model into the likelihood function, explicitly maintaining the connection with the quantity of interest. No assumptions about the linearity of the problem or the shape of the probability distribution functions are required, and there is no need to morph signal and background spectra as a function of nuisance parameters. By expressing the problem in terms of Bayesian Networks, we have developed an inference algorithm based on a Markov Chain Monte Carlo to calculate the posterior probability. A clever description of the detector response model in terms of parametric matrices allows us to study the impact of systematic variations of any parameter on the final results. Our approach not only provides the desired information on the parameter of interest, but also potential constraints on the response model. Our results are consistent with recent published analyses and further refine the parameters of the detector response model., Comment: 24 pages, 12 figures, 1 table
Published: 2023

4. Emergence of Anaplasma Species Related to A. phagocytophilum and A. platys in Senegal

Author: Rosanna Zobba, Claudio Murgia, Mustapha Dahmani, Oleg Mediannikov, Bernard Davoust, Roberta Piredda, Eleonora Schianchi, Alessandra Scagliarini, Marco Pittau, Alberto Alberti, Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Microbes évolution phylogénie et infections (MEPHI), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Institut Hospitalier Universitaire Méditerranée Infection (IHU Marseille), University of Bologna/Università di Bologna, and COMBE, Isabelle
Subjects: tick-borne diseases, [SDV]Life Sciences [q-bio], Organic Chemistry, General Medicine, obligate intracellular bacteria, Anaplasma diversity, zoonosis, one health, Catalysis, Computer Science Applications, Inorganic Chemistry, [SDV] Life Sciences [q-bio], Physical and Theoretical Chemistry, Molecular Biology, Spectroscopy
Abstract: International audience; The genus Anaplasma (Anaplasmataceae, Rickettsiales) includes tick-transmitted bacterial species of importance to both veterinary and human medicine. Apart from the traditionally recognized six Anaplasma species (A. phagocytophilum, A. platys, A. bovis, A. ovis, A. centrale, A. marginale), novel strains and candidate species, also of relevance to veterinary and human medicine, are emerging worldwide. Although species related to the zoonotic A. platys and A. phagocytophilum have been reported in several African and European Mediterranean countries, data on the presence of these species in sub-Saharan countries are still lacking. This manuscript reports the investigation of Anaplasma strains related to zoonotic species in ruminants in Senegal by combining different molecular tests and phylogenetic approaches. The results demonstrated a recent introduction of Candidatus (Ca) Anaplasma turritanum, a species related to the pathogenic A. platys, possibly originating by founder effect. Further, novel undetected strains related to Candidatus (Ca) Anaplasma cinensis were detected in cattle. Based on groEL and gltA molecular comparisons, we propose including these latter strains into the Candidatus (Ca) Anaplasma africanum species. Finally, we also report the emergence of Candidatus (Ca) A. boleense in Senegal. Collectively, results confirm that Anaplasma species diversity is greater than expected and should be further investigated, and that Anaplasma routine diagnostic procedures and epidemiological surveillance should take into account specificity issues raised by the presence of these novel strains, suggesting the use of a One Health approach for the management of Anaplasmataceae in sub-Saharan Africa.
Published: 2023

5. Search for low-mass dark matter WIMPs with 12 ton-day exposure of DarkSide-50

Author: Agnes, P., Albuquerque, I.F.M., Alexander, T., Alton, A.K., Ave, M., Back, H.O., Batignani, G., Biery, K., Bocci, V., Bonivento, W.M., Bottino, B., Bussino, S., Cadeddu, M., Cadoni, M., Calaprice, F., Caminata, A., Campos, M.D., Canci, N., Caravati, M., Cariello, M., Carlini, M., Carpinelli, M., Cataudella, V., Cavalcante, P., Cavuoti, S., Chashin, S., Chepurnov, A., Cicalò, C., Covone, G., d'Angelo, D., Davini, S., de Candia, A., de Cecco, S., de Filippis, G., de Rosa, G., Derbin, A.V., Devoto, A., d'Incecco, M., Dionisi, C., Dordei, F., Downing, M., d'Urso, D., Fairbairn, M., Fiorillo, G., Franco, D., Gabriele, F., Galbiati, C., Ghiano, C., Giganti, C., Giovanetti, G.K., Goretti, A.M., Di Cortona, G. Grilli, Grobov, A., Gromov, M., Guan, M., Gulino, M., Hackett, B.R., Herner, K., Hessel, T., Hosseini, B., Hubaut, F., Hungerford, E.V., Ianni, An., Ippolito, V., Keeter, K., Kendziora, C.L., Kimura, M., Kochanek, I., Korablev, D., Korga, G., Kubankin, A., Kuss, M., La Commara, M., Lai, M., Li, X., Lissia, M., Longo, G., Lychagina, O., Machulin, I.N., Mapelli, L.P., Mari, S.M., Maricic, J., Martoff, C.J., Messina, A., Milincic, R., Monroe, J., Morrocchi, M., Mougeot, X., Muratova, V.N., Musico, P., Nozdrina, A.O., Oleinik, A., Ortica, F., Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Pelczar, K., Pelliccia, N., Piacentini, S., Picciau, E., Pocar, A., Poehlmann, D.M., Pordes, S., Poudel, S.S., Pralavorio, P., Price, D.D., Ragusa, F., Razeti, M., Razeto, A., Renshaw, A.L., Rescigno, M., Rode, J., Romani, A., Sablone, D., Samoylov, O., Sands, W., Sanfilippo, S., Sanford, E., Savarese, C., Schlitzer, B., Semenov, D.A., Shchagin, A., Sheshukov, A., Skorokhvatov, M.D., Smirnov, O., Sotnikov, A., Stracka, S., Suvorov, Y., Tartaglia, R., Testera, G., Tonazzo, A., Unzhakov, E.V., Vishneva, A., Vogelaar, R.B., Wada, M., Wang, H., Wang, Y., Westerdale, S., Wojcik, M.M., Xiao, X., Yang, C., Zuzel, G., Agnes, P., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Ave, M., Back, H. O., Batignani, G., Biery, K., Bocci, V., Bonivento, W. M., Bottino, B., Bussino, S., Cadeddu, M., Cadoni, M., Calaprice, F., Caminata, A., Canci, N., Caravati, M., Cargioli, N., Cariello, M., Carlini, M., Cataudella, V., Cavalcante, P., Cavuoti, S., Chashin, S., Chepurnov, A., Cicalò, C., Covone, G., D’Angelo, D., Davini, S., De Candia, A., De Cecco, S., De Filippis, G., De Rosa, G., Derbin, A. V., Devoto, A., D’Incecco, M., Dionisi, C., Dordei, F., Downing, M., D’Urso, D., Fiorillo, G., Franco, D., Gabriele, F., Galbiati, C., Ghiano, C., Giganti, C., Giovanetti, G. K., Goretti, A. M., Grilli di Cortona, G., Grobov, A., Gromov, M., Guan, M., Gulino, M., Hackett, B. R., Herner, K., Hessel, T., Hosseini, B., Hubaut, F., Hungerford, E. V., Ianni, An., Ippolito, V., Keeter, K., Kendziora, C. L., Kimura, M., Kochanek, I., Korablev, D., Korga, G., Kubankin, A., Kuss, M., La Commara, M., Lai, M., Li, X., Lissia, M., Longo, G., Lychagina, O., Machulin, I. N., Mapelli, L. P., Mari, S. M., Maricic, J., Messina, A., Milincic, R., Monroe, J., Morrocchi, M., Mougeot, X., Muratova, V. N., Musico, P., Nozdrina, A. O., Oleinik, A., Ortica, F., Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Pelczar, K., Pelliccia, N., Piacentini, S., Pocar, A., Poehlmann, D. M., Pordes, S., Poudel, S. S., Pralavorio, P., Price, D. D., Ragusa, F., Razeti, M., Razeto, A., Renshaw, A. L., Rescigno, M., Rode, J., Romani, A., Sablone, D., Samoylov, O., Sands, W., Sanfilippo, S., Sandford, E., Savarese, C., Schlitzer, B., Semenov, D. A., Shchagin, A., Sheshukov, A., Skorokhvatov, M. D., Smirnov, O., Sotnikov, A., Stracka, S., Suvorov, Y., Tartaglia, R., Testera, G., Tonazzo, A., Unzhakov, E. V., Vishneva, A., Vogelaar, R. B., Wada, M., Wang, H., Wang, Y., Westerdale, S., Wojcik, M. M., Xiao, X., Yang, C., Zuzel, G., Royal Holloway [University of London] (RHUL), Universidade de São Paulo = University of São Paulo (USP), Pacific Northwest National Laboratory (PNNL), University of South Dakota [Vermillion] (USD), Istituto Nazionale di Fisica Nucleare [Pisa] (INFN), Istituto Nazionale di Fisica Nucleare (INFN), Fermi National Accelerator Laboratory (Fermilab), Istituto Nazionale di Fisica Nucleare [Sezione di Roma 1] (INFN), Istituto Nazionale di Fisica Nucleare, Istituto Nazionale di Fisica Nucleare, Sezione di Cagliari (INFN, Sezione di Cagliari), Università degli studi di Genova = University of Genoa (UniGe), Princeton University, Istituto Nazionale di Fisica Nucleare, Sezione di Genova (INFN, Sezione di Genova), Gran Sasso Science Institute, INFN, University of Naples Federico II = Università degli studi di Napoli Federico II, Virginia Tech [Blacksburg], D.V. Skobeltsyn Institute of Nuclear Physics (SINP), Lomonosov Moscow State University (MSU), Istituto Nazionale di Fisica Nucleare, Sezione di Milano (INFN), Università degli Studi di Cagliari = University of Cagliari (UniCa), University of Massachusetts System (UMASS), Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Istituto Nazionale di Fisica Nucleare, Sezione di Napoli (INFN, Sezione di Napoli), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), INFN Frascati, Institute of Molecular Genetics of National Research Centre «Kurchatov Institute» [Moscow, Russia], Russian Academy of Sciences [Moscow] (RAS), Institute of High Energy Physics [Beijing] (IHEP), Chinese Academy of Sciences [Changchun Branch] (CAS), Università degli Studi di Enna ' KORE ' = Kore University of Enna, Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), University of Houston, Black Hills State University, Nicolaus Copernicus Astronomical Cente (AstroCeNT), Joint Institute for Nuclear Research (JINR), Belgorod National Research University, University of California [Los Angeles] (UCLA), University of California (UC), University of Hawai'i [Hilo], Laboratoire National Henri Becquerel (LNHB), Département Métrologie Instrumentation & Information (DM2I), Laboratoire d'Intégration des Systèmes et des Technologies (LIST (CEA)), Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Laboratoire d'Intégration des Systèmes et des Technologies (LIST (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Département d'instrumentation Numérique (DIN (CEA-LIST)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Università degli Studi di Perugia = University of Perugia (UNIPG), Istituto Nazionale di Fisica Nucleare, Sezione di Catania (INFN), Università degli studi di Catania = University of Catania (Unict), INFN Laboratori Nazionali del Gran Sasso, University of Massachusetts [Amherst] (UMass Amherst), University of Manchester [Manchester], Università degli Studi di Milano = University of Milan (UNIMI), Università degli Studi Roma Tre = Roma Tre University (ROMA TRE), Moscow State Engineering Physics Institute (MEPhI), Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome] (UNIROMA), Nicolaus Copernicus Astronomical Center (AstroCENT), Uniwersytet Jagielloński w Krakowie = Jagiellonian University (UJ), SCOAP, DarkSide-50, and HEP, INSPIRE
Subjects: WIMP nucleon: scattering, data analysis method, Cosmology and Nongalactic Astrophysics (astro-ph.CO), dark matter: interaction, [PHYS.HEXP] Physics [physics]/High Energy Physics - Experiment [hep-ex], dark matter interaction, background: model, FOS: Physical sciences, WIMP: mass, WIMP nucleon scattering, spin: dependence, Detector calibration, WIMP: dark matter, spin dependence, argon: target, dark matter, High Energy Physics - Experiment, High Energy Physics - Experiment (hep-ex), [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], detector: calibration, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], cross section: upper limit, instrumentation, detector, mass dependence, Gran Sasso, WIMP mass, radioactivity, argon, [PHYS.ASTR] Physics [physics]/Astrophysics [astro-ph], [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], experimental results, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract: We report on the search for dark matter WIMPs in the mass range below 10 GeV/c$^2$, from the analysis of the entire dataset acquired with a low-radioactivity argon target by the DarkSide-50 experiment at LNGS. The new analysis benefits from more accurate calibration of the detector response, improved background model, and better determination of systematic uncertainties, allowing us to accurately model the background rate and spectra down to 0.06 keV$_{er}$. A 90% C.L. exclusion limit for the spin-independent cross section of 3 GeV/c$^2$ mass WIMP on nucleons is set at 6$\times$10$^{-43}$ cm$^2$, about a factor 10 better than the previous DarkSide-50 limit. This analysis extends the exclusion region for spin-independent dark matter interactions below the current experimental constraints in the $[1.2, 3.6]$ GeV/c$^2$ WIMP mass range., 11 pages, 12 figures
Published: 2023

6. Evidence for increasing global wheat yield potential

Author: Jose Rafael Guarin, Pierre Martre, Frank Ewert, Heidi Webber, Sibylle Dueri, Daniel Calderini, Matthew Reynolds, Gemma Molero, Daniel Miralles, Guillermo Garcia, Gustavo Slafer, Francesco Giunta, Diego N L Pequeno, Tommaso Stella, Mukhtar Ahmed, Phillip D Alderman, Bruno Basso, Andres G Berger, Marco Bindi, Gennady Bracho-Mujica, Davide Cammarano, Yi Chen, Benjamin Dumont, Ehsan Eyshi Rezaei, Elias Fereres, Roberto Ferrise, Thomas Gaiser, Yujing Gao, Margarita Garcia-Vila, Sebastian Gayler, Zvi Hochman, Gerrit Hoogenboom, Leslie A Hunt, Kurt C Kersebaum, Claas Nendel, Jørgen E Olesen, Taru Palosuo, Eckart Priesack, Johannes W M Pullens, Alfredo Rodríguez, Reimund P Rötter, Margarita Ruiz Ramos, Mikhail A Semenov, Nimai Senapati, Stefan Siebert, Amit Kumar Srivastava, Claudio Stöckle, Iwan Supit, Fulu Tao, Peter Thorburn, Enli Wang, Tobias Karl David Weber, Liujun Xiao, Zhao Zhang, Chuang Zhao, Jin Zhao, Zhigan Zhao, Yan Zhu, Senthold Asseng, University of Florida [Gainesville] (UF), Center for Climate Systems Research [New York] (CCSR), Columbia University [New York], Écophysiologie des Plantes sous Stress environnementaux (LEPSE), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro Montpellier, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Leibniz-Zentrum für Agrarlandschaftsforschung = Leibniz Centre for Agricultural Landscape Research (ZALF), Institute of Crop Science and Resource Conservation [Bonn] (INRES), Rheinische Friedrich-Wilhelms-Universität Bonn, Universidad Austral de Chile, International Maize and Wheat Improvement Center (CIMMYT), Consultative Group on International Agricultural Research [CGIAR] (CGIAR), KWS Momont SAS, Universitad de Buenos Aires = University of Buenos Aires [Argentina], Instituto de Investigaciones Fisiologicas y Ecologicas Vinculadas a la Agricultura (IFEVA), Consejo Nacional de Investigaciones Científicas y Técnicas [Buenos Aires] (CONICET)-Facultad de Agronomía [Buenos Aires], Universidad de Buenos Aires [Buenos Aires] (UBA)-Universidad de Buenos Aires [Buenos Aires] (UBA), Universitat de Lleida, Institució Catalana de Recerca i Estudis Avançats (ICREA), Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Pir Mehr Ali Shah Arid Agriculture University = PMAS-Arid Agriculture University Rawalpindi (AAUR), Swedish University of Agricultural Sciences (SLU), Oklahoma State University [Stillwater] (OSU), Michigan State University [East Lansing], Michigan State University System, Instituto Nacional de Investigación Agropecuaria (INIA), Department of Agriculture, Food, Environment and Forestry (DAGRI), Università degli Studi di Firenze = University of Florence (UniFI), Georg-August-University = Georg-August-Universität Göttingen, Purdue University [West Lafayette], Institute of geographical sciences and natural resources research [CAS] (IGSNRR), Chinese Academy of Sciences [Beijing] (CAS), Gembloux Agro-Bio Tech [Gembloux], Université de Liège, Instituto de Agricultura Sostenible - Institute for Sustainable Agriculture (IAS CSIC), Consejo Superior de Investigaciones Científicas [Madrid] (CSIC), Universidad de Córdoba = University of Córdoba [Córdoba], University of Hohenheim, Commonwealth Scientific and Industrial Research Organisation [Canberra] (CSIRO), University of Guelph, Global Change Research Centre (CzechGlobe), University of Potsdam = Universität Potsdam, Aarhus University [Aarhus], Natural Resources Institute Finland (LUKE), Helmholtz Zentrum München = German Research Center for Environmental Health, Universidad de Castilla-La Mancha = University of Castilla-La Mancha (UCLM), Centro de Estudios e Investigación para la Gestión de Riesgos Agrarios y Medioambientales (CEIGRAM), Universidad Politécnica de Madrid (UPM), Centre for Biodiversity and Sustainable Land-use [University of Göttingen] (CBL), Rothamsted Research, Biotechnology and Biological Sciences Research Council (BBSRC), Washington State University (WSU), Wageningen University and Research [Wageningen] (WUR), Universität Kassel [Kassel], Zhejiang University, Nanjing Agricultural University (NAU), Building artificial Intelligence between trust, Responsibility and Decision (BIRD), Department of Complex Systems, Artificial Intelligence & Robotics (LORIA - AIS), Laboratoire Lorrain de Recherche en Informatique et ses Applications (LORIA), Institut National de Recherche en Informatique et en Automatique (Inria)-Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche en Informatique et en Automatique (Inria)-Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS)-Laboratoire Lorrain de Recherche en Informatique et ses Applications (LORIA), Institut National de Recherche en Informatique et en Automatique (Inria)-Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche en Informatique et en Automatique (Inria)-Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS), Beijing Normal University (BNU), China Agricultural University (CAU), Technische Universität Munchen - Université Technique de Munich [Munich, Allemagne] (TUM), International Wheat Yield Partnership (IWYP, Grant IWYP115) and the International Maize and Wheat Improvement Center (CIMMYT)., IWYP, CIMMYT (Mexico), and the Chilean Technical and Scientific Research Council (CONICYT) by FONDECYT Project 1141048, National Natural Science Foundation of China (Project Nos. 31761143006 and 41571493), Ministry of Education, Youth and Sports of Czech Republic through SustEs (CZ.02.1.01/0.0/0.0/16_019/000797), Biotechnology and Biological Sciences Research Council (BBSRC) through Designing Future Wheat (BB/P016855/1) and Achieving Sustainable Agricultural Systems (NE/N018125/1)., International Wheat Yield Partnership, International Maize and Wheat Improvement Center, Comisión Nacional de Investigación Científica y Tecnológica (Chile), Fondo Nacional de Desarrollo Científico y Tecnológico (Chile), National Natural Science Foundation of China, Ministry of Education, Youth and Sports (Czech Republic), and Biotechnology and Biological Sciences Research Council (UK)
Subjects: Crop Population, Crop Model Ensemble, Global Food Security Supplementary Material For This Article Is Available Online, Radiation Use Efficiency, Wheat Potential Yield, Yield Increase, Climate, Global Food Security, crop model ensemble, Grain Number, global food security Supplementary material for this article is available online, [SDV.BV]Life Sciences [q-bio]/Vegetal Biology, Photosynthesis, yield increase, General Environmental Science, WIMEK, radiation use efficiency, Renewable Energy, Sustainability and the Environment, Spring Wheat, Public Health, Environmental and Occupational Health, Letter, wheat potential yield, global food security, Food Demand, ddc, Solar-Radiation, Water Systems and Global Change, Biomass Accumulation
Abstract: Wheat is the most widely grown food crop, with 761 Mt produced globally in 2020. To meet the expected grain demand by mid-century, wheat breeding strategies must continue to improve upon yield-advancing physiological traits, regardless of climate change impacts. Here, the best performing doubled haploid (DH) crosses with an increased canopy photosynthesis from wheat field experiments in the literature were extrapolated to the global scale with a multi-model ensemble of process-based wheat crop models to estimate global wheat production. The DH field experiments were also used to determine a quantitative relationship between wheat production and solar radiation to estimate genetic yield potential. The multi-model ensemble projected a global annual wheat production of 1050 ± 145 Mt due to the improved canopy photosynthesis, a 37% increase, without expanding cropping area. Achieving this genetic yield potential would meet the lower estimate of the projected grain demand in 2050, albeit with considerable challenges., This study was a part of the Agricultural Model Intercomparison and Improvement Project (AgMIP) Wheat Phase 4. The study was supported by the International Wheat Yield Partnership (IWYP, Grant IWYP115) and the International Maize and Wheat Improvement Center (CIMMYT). Experiments carried out in Valdivia (Chile) were funded by IWYP, CIMMYT (Mexico), and the Chilean Technical and Scientific Research Council (CONICYT) by FONDECYT Project 1141048. The experimental work conducted at Valdivia by Dr Jaime Herrera (UACh) is appreciated. F T was supported by the National Natural Science Foundation of China (Project Nos. 31761143006 and 41571493). K C K was supported by the Ministry of Education, Youth and Sports of Czech Republic through SustEs (CZ.02.1.01/0.0/0.0/16_019/000797). Rothamsted Research receives support from the Biotechnology and Biological Sciences Research Council (BBSRC) through Designing Future Wheat (BB/P016855/1) and Achieving Sustainable Agricultural Systems (NE/N018125/1).
Published: 2022

7. There is a growing realization that the complexity of model ensemble studies depends not only on the models used but also on the experience and approach used by modelers to calibrate and validate results, which remain a source of uncertainty. Here, we applied a multi-criteria decision-making method to investigate the rationale applied by modelers in a model ensemble study where 12 process-based different biogeochemical model types were compared across five successive calibration stages. The modelers shared a common level of agreement about the importance of the variables used to initialize their models for calibration. However, we found inconsistency among modelers when judging the importance of input variables across different calibration stages. The level of subjective weighting attributed by modelers to calibration data decreased sequentially as the extent and number of variables provided increased. In this context, the perceived importance attributed to variables such as the fertilization rate, irrigation regime, soil texture, pH, and initial levels of soil organic carbon and nitrogen stocks was statistically different when classified according to model types. The importance attributed to input variables such as experimental duration, gross primary production, and netecosystem exchange varied significantly according to the length of the modeler’s experience. We argue that the gradual access to input data across the five calibration stages negatively influenced the consistency of the interpretations made by the modelers, with cognitive bias in 'trial-and-error' calibration routines. Our study highlights that overlooking human and social attributes is critical in the outcomes of modeling and model intercomparison studies. While complexity of the processes captured in the model algorithms and parameterization is important, we contend that (1) the modeler’s assumptions on the extent to which parameters should be altered and (2) modeler perceptions of the importance of model parameters are just as critical in obtaining a quality model calibration as numerical or analytical details

Author: Fabrizio Albanito, David McBey, Matthew Harrison, Pete Smith, Fiona Ehrhardt, Arti Bhatia, Gianni Bellocchi, Lorenzo Brilli, Marco Carozzi, Karen Christie, Jordi Doltra, Christopher Dorich, Luca Doro, Peter Grace, Brian Grant, Joël Léonard, Mark Liebig, Cameron Ludemann, Raphael Martin, Elizabeth Meier, Rachelle Meyer, Massimiliano De Antoni Migliorati, Vasileios Myrgiotis, Sylvie Recous, Renáta Sándor, Val Snow, Jean-François Soussana, Ward N. Smith, Nuala Fitton, Producció Vegetal, Cultius Extensius Sostenibles, University of Aberdeen, School of Biological Sciences, University of Aberdeen, Aberdeen, UK, Tasmanian Institute of Agriculture, University of Tasmania [Hobart, Australia] (UTAS), RITTMO Agroenvironnement (RITTMO), Collège de Direction (CODIR), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Indian Council of Agricultural Research (ICAR), Unité Mixte de Recherche sur l'Ecosystème Prairial - UMR (UREP), VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institute for BioEconomy [Sesto Fiorentino] (IBE | CNR), National Research Council of Italy | Consiglio Nazionale delle Ricerche (CNR), Ecologie fonctionnelle et écotoxicologie des agroécosystèmes (ECOSYS), AgroParisTech-Université Paris-Saclay-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institut de Recerca i Tecnologia Agroalimentàries = Institute of Agrifood Research and Technology (IRTA), Natural Resource Ecology Laboratory [Fort Collins] (NREL), Colorado State University [Fort Collins] (CSU), Texas A and M AgriLife Research, Texas A&M University System, Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Queensland University of Technology [Brisbane] (QUT), Ottawa Research and Development Center, Agriculture and Agri-Food (AAFC), Transfrontalière BioEcoAgro - UMR 1158 (BioEcoAgro), Université d'Artois (UA)-Université de Liège-Université de Picardie Jules Verne (UPJV)-Université du Littoral Côte d'Opale (ULCO)-Université de Lille-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-JUNIA (JUNIA), Université catholique de Lille (UCL)-Université catholique de Lille (UCL), USDA-ARS, Northern Plains Agricultural Research Laboratory, Sidney, Montana, Cameron Ludemann Consulting, CSIRO Agriculture and Food (CSIRO), Faculty of Veterinary & Agricultural Sciences, University of Melbourne, Parkville, Victoria, School of Geosciences, University of Edimburgh, Fractionnement des AgroRessources et Environnement (FARE), Université de Reims Champagne-Ardenne (URCA)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Centre for Agricultural Research [Budapest] (ATK), Hungarian Academy of Sciences (MTA), AgResearch Ltd, and Institute of Biological and Environmental Sciences, University of Aberdeen
Subjects: model ensembles, biogeochemical models, model calibration, Nitrogen, [SDE.MCG]Environmental Sciences/Global Changes, Uncertainty, General Chemistry, Carbon, Soil, model intercomparison, climate change, greenhouse gases, AgMIP, Environmental Chemistry, multi-criteria decision-making, Humans, soil carbon, Ecosystem
Abstract: There is a growing realization that the complexity of model ensemble studies depends not only on the models used but also on the experience and approach used by modelers to calibrate and validate results, which remain a source of uncertainty. Here, we applied a multi-criteria decision-making method to investigate the rationale applied by modelers in a model ensemble study where 12 process-based different biogeochemical model types were compared across five successive calibration stages. The modelers shared a common level of agreement about the importance of the variables used to initialize their models for calibration. However, we found inconsistency among modelers when judging the importance of input variables across different calibration stages. The level of subjective weighting attributed by modelers to calibration data decreased sequentially as the extent and number of variables provided increased. In this context, the perceived importance attributed to variables such as the fertilization rate, irrigation regime, soil texture, pH, and initial levels of soil organic carbon and nitrogen stocks was statistically different when classified according to model types. The importance attributed to input variables such as experimental duration, gross primary production, and net ecosystem exchange varied significantly according to the length of the modeler’s experience. We argue that the gradual access to input data across the five calibration stages negatively influenced the consistency of the interpretations made by the modelers, with cognitive bias in “trial-and-error” calibration routines. Our study highlights that overlooking human and social attributes is critical in the outcomes of modeling and model intercomparison studies. While complexity of the processes captured in the model algorithms and parameterization is important, we contend that (1) the modeler’s assumptions on the extent to which parameters should be altered and (2) modeler perceptions of the importance of model parameters are just as critical in obtaining a quality model calibration as numerical or analytical details. info:eu-repo/semantics/acceptedVersion
Published: 2022

8. Search for dark matter particle interactions with electron final states with DarkSide-50

Author: Collaboration, The DarkSide-50, Agnes, P., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Ave, M., Back, H. O., Batignani, G., Biery, K., Bocci, V., Bonivento, W. M., Bottino, B., Bussino, S., Cadeddu, M., Cadoni, M., Calaprice, F., Caminata, A., Campos, M. D., Canci, N., Caravati, M., Cariello, M., Carlini, M., Carpinelli, M., Cataudella, V., Cavalcante, P., Cavuoti, S., Chashin, S., Chepurnov, A., Cicalò, C., Covone, G., D'Angelo, D., Davini, S., De Candia, A., De Cecco, S., De Filippis, G., De Rosa, G., Derbin, A. V., Devoto, A., D'Incecco, M., Dionisi, C., Dordei, F., Downing, M., D'Urso, D., Fiorillo, G., Franco, D., Gabriele, F., Galbiati, C., Ghiano, C., Giganti, C., Giovanetti, G. K., Goretti, A. M., di Cortona, G. Grilli, Grobov, A., Gromov, M., Guan, M., Gulino, M., Hackett, B. R., Herner, K., Hessel, T., Hosseini, B., Hubaut, F., Hungerford, E. V., Ianni, An., Ippolito, V., Keeter, K., Kendziora, C. L., Kimura, M., Kochanek, I., Korablev, D., Korga, G., Kubankin, A., Kuss, M., La Commara, M., Lai, M., Li, X., Lissia, M., Longo, G., Lychagina, O., Machulin, I. N., Mapelli, L. P., Mari, S. M., Maricic, J., Messina, A., Milincic, R., Monroe, J., Morrocchi, M., Mougeot, X., Muratova, V. N., Musico, P., Nozdrina, A. O., Oleinik, A., Ortica, F., Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Pelczar, K., Pelliccia, N., Piacentini, S., Picciau, E., Pocar, A., Poehlmann, D. M., Pordes, S., Poudel, S. S., Pralavorio, P., Price, D. D., Ragusa, F., Razeti, M., Razeto, A., Renshaw, A. L., Rescigno, M., Rode, J., Romani, A., Sablone, D., Samoylov, O., Sands, W., Sanfilippo, S., Sanford, E., Savarese, C., Schlitzer, B., Semenov, D. A., Shchagin, A., Sheshukov, A., Skorokhvatov, M. D., Smirnov, O., Sotnikov, A., Stracka, S., Suvorov, Y., Tartaglia, R., Testera, G., Tonazzo, A., Unzhakov, E. V., Vishneva, A., Vogelaar, R. B., Wada, M., Wang, H., Wang, Y., Westerdale, S., Wojcik, M. M., Xiao, X., Yang, C., Zuzel, G., Royal Holloway [University of London] (RHUL), Universidade de São Paulo = University of São Paulo (USP), Pacific Northwest National Laboratory (PNNL), University of South Dakota [Vermillion] (USD), Istituto Nazionale di Fisica Nucleare [Pisa] (INFN), Istituto Nazionale di Fisica Nucleare (INFN), Fermi National Accelerator Laboratory (Fermilab), Istituto Nazionale di Fisica Nucleare [Sezione di Roma 1] (INFN), Istituto Nazionale di Fisica Nucleare, Istituto Nazionale di Fisica Nucleare, Sezione di Cagliari (INFN, Sezione di Cagliari), Università degli studi di Genova = University of Genoa (UniGe), Università degli Studi di Cagliari = University of Cagliari (UniCa), Princeton University, Istituto Nazionale di Fisica Nucleare, Sezione di Genova (INFN, Sezione di Genova), King‘s College London, Gran Sasso Science Institute, INFN, University of Naples Federico II = Università degli studi di Napoli Federico II, Virginia Tech [Blacksburg], D.V. Skobeltsyn Institute of Nuclear Physics (SINP), Lomonosov Moscow State University (MSU), Università degli Studi di Milano = University of Milan (UNIMI), Saint Petersburg Nuclear Physics Institute RAS, St Petersburg Nuclear Physics Institute, University of Massachusetts System (UMASS), Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Department of Physics, Princeton University (DPPU), INFN Frascati, Institute of Molecular Genetics of National Research Centre «Kurchatov Institute» [Moscow, Russia], Russian Academy of Sciences [Moscow] (RAS), Institute of High Energy Physics [Beijing] (IHEP), Chinese Academy of Sciences [Changchun Branch] (CAS), Università degli Studi di Enna ' KORE ' = Kore University of Enna, Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), University of Houston [Clear Lake], Black Hills State University, Nicolaus Copernicus Astronomical Cente (AstroCeNT), Joint Institute for Nuclear Research (JINR), University of Houston, Belgorod National Research University, University of California (UC), University of Hawai'i [Hilo], Laboratoire National Henri Becquerel (LNHB), Département Métrologie Instrumentation & Information (DM2I), Laboratoire d'Intégration des Systèmes et des Technologies (LIST (CEA)), Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Laboratoire d'Intégration des Systèmes et des Technologies (LIST (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Département d'instrumentation Numérique (DIN (CEA-LIST)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Università degli Studi di Perugia = University of Perugia (UNIPG), Istituto Nazionale di Fisica Nucleare, Sezione di Catania (INFN), Università degli studi di Catania = University of Catania (Unict), University of Massachusetts [Amherst] (UMass Amherst), University of California [Davis] (UC Davis), University of Manchester [Manchester], Università degli Studi di Roma Tor Vergata [Roma], Uniwersytet Jagielloński w Krakowie = Jagiellonian University (UJ), DarkSide Collaboration, ANR-10-LABX-0023,UnivEarthS,Earth - Planets - Universe: observation, modeling, transfer(2010), ANR-18-IDEX-0001,Université de Paris,Université de Paris(2018), European Project: 952480,DarkWave, HEP, INSPIRE, DarkSide-50, Agnes, P., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Ave, M., Back, H. O., Batignani, G., Biery, K., Bocci, V., Bonivento, W. M., Bottino, B., Bussino, S., Cadeddu, M., Cadoni, M., Calaprice, F., Caminata, A., Campos, M. D., Canci, N., Caravati, M., Cargioli, N., Cariello, M., Carlini, M., Cataudella, V., Cavalcante, P., Cavuoti, S., Chashin, S., Chepurnov, A., Cicalò, C., Covone, G., D’Angelo, D., Davini, S., De Candia, A., De Cecco, S., De Filippis, G., De Rosa, G., Derbin, A. V., Devoto, A., D’Incecco, M., Dionisi, C., Dordei, F., Downing, M., D’Urso, D., Fiorillo, G., Franco, D., Gabriele, F., Galbiati, C., Ghiano, C., Giganti, C., Giovanetti, G. K., Goretti, A. M., Grilli di Cortona, G., Grobov, A., Gromov, M., Guan, M., Gulino, M., Hackett, B. R., Herner, K., Hessel, T., Hosseini, B., Hubaut, F., Hungerford, E. V., Ianni, An., Ippolito, V., Keeter, K., Kendziora, C. L., Kimura, M., Kochanek, I., Korablev, D., Korga, G., Kubankin, A., Kuss, M., La Commara, M., Lai, M., Li, X., Lissia, M., Longo, G., Lychagina, O., Machulin, I. N., Mapelli, L. P., Mari, S. M., Maricic, J., Messina, A., Milincic, R., Monroe, J., Morrocchi, M., Mougeot, X., Muratova, V. N., Musico, P., Nozdrina, A. O., Oleinik, A., Ortica, F., Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Pelczar, K., Pelliccia, N., Piacentini, S., Pocar, A., Poehlmann, D. M., Pordes, S., Poudel, S. S., Pralavorio, P., Price, D. D., Ragusa, F., Razeti, M., Razeto, A., Renshaw, A. L., Rescigno, M., Rode, J., Romani, A., Sablone, D., Samoylov, O., Sands, W., Sanfilippo, S., Sandford, E., Savarese, C., Schlitzer, B., Semenov, D. A., Shchagin, A., Sheshukov, A., Skorokhvatov, M. D., Smirnov, O., Sotnikov, A., Stracka, S., Suvorov, Y., Tartaglia, R., Testera, G., Tonazzo, A., Unzhakov, E. V., Vishneva, A., Vogelaar, R. B., Wada, M., Wang, H., Wang, Y., Westerdale, S., Wojcik, M. M., Xiao, X., Yang, C., and Zuzel, G.
Subjects: Cosmology and Nongalactic Astrophysics (astro-ph.CO), [PHYS.HEXP] Physics [physics]/High Energy Physics - Experiment [hep-ex], kinetic, General Physics and Astronomy, mixing angle, FOS: Physical sciences, coupling constant: upper limit, dark matter: direct detection, dark matter direct detection, coupling constant upper limit, neutrino mixing, High Energy Physics - Experiment, dark matter mass, High Energy Physics - Experiment (hep-ex), ionization, Dark matter, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], coupling: (axion 2electron), [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], signal processing, electron: final state, instrumentation, photon: hidden sector, axion: dark matter, photon mixing, dark matter: mass, electrons, Neutrino sterile, neutrino: sterile, particle: interaction, liquid argon, radioactivity, photon: mixing, particle interaction, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], neutrino: mixing, [PHYS.ASTR] Physics [physics]/Astrophysics [astro-ph], electron final state, ionizing radiation, mixing: kinetic, photon hidden sector, experimental results, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract: We present a search for dark matter particles with sub-GeV/$c^2$ masses whose interactions have final state electrons using the DarkSide-50 experiment's (12306 $\pm$ 184) kg d low-radioactivity liquid argon exposure. By analyzing the ionization signals, we exclude new parameter space for the dark matter-electron cross section $\bar{\sigma}_e$, the axioelectric coupling constant $g_{Ae}$, and the dark photon kinetic mixing parameter $\kappa$. We also set the first dark matter direct-detection constraints on the mixing angle $\left|U_{e4}\right|^2$ for keV sterile neutrinos., Comment: 6 pages, 2 figures
Published: 2022

9. Feasibility Study and Porting of the Damped Least Square Algorithm on FPGA

Author: Carlo Sau, Luigi Raffo, Claudio Rubattu, Luca Fanni, Tiziana Fanni, Francesca Palumbo, Universita degli Studi di Cagliari [Cagliari], Università degli Studi di Sassari [Sassari] (UNISS), Institut d'Électronique et des Technologies du numéRique (IETR), Université de Nantes (UN)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS), European UnionEuropean Union (EU) [732105], University of Sassari through the Fondo di Ateneo per la Ricerca 2019, European Project: 9732105(1998), Nantes Université (NU)-Université de Rennes 1 (UR1), Università degli Studi di Cagliari = University of Cagliari (UniCa), Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Université de Nantes (UN)-Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), and Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS)
Subjects: General Computer Science, Computer science, robotic arm controller, Trajectory, Symmetric multiprocessor system, 02 engineering and technology, Kinematics, Robot kinematics, Porting, [SPI]Engineering Sciences [physics], reconfigurable architectures, Control theory, Datapath, Cyber physical systems, design automation, 0202 electrical engineering, electronic engineering, information engineering, hardware, General Materials Science, Field-programmable gate array, field programmable gate arrays, Inverse kinematics, business.industry, General Engineering, 020207 software engineering, Robotics, damped least square, Manipulators, Embedded system, Task analysis, 020201 artificial intelligence & image processing, embedded systems, Artificial intelligence, lcsh:Electrical engineering. Electronics. Nuclear engineering, heterogeneous platforms, business, Robotic arm, lcsh:TK1-9971
Abstract: International audience; Modern embedded computing platforms used within Cyber-Physical Systems (CPS) are nowadays leveraging more and more often on heterogeneous computing substrates, such as newest Field Programmable Gate Array (FPGA) devices. Compared to general purpose platforms, which have a fixed datapath, FPGAs provide designers the possibility of customizing part of the computing infrastructure, to better shape the execution on the application needs/features, and offer high efficiency in terms of timing and power performance, while naturally featuring parallelism. In the context of FPGA-based CPSs, this article has a two fold mission. On the one hand, it presents an analysis of the Damped Least Square (DLS) algorithm for a perspective hardware implementation. On the other hand, it describes the implementation of a robotic arm controller based on the DLS to numerically solve Inverse Kinematics problems over a heterogeneous FPGA. Assessments involve a Trossen Robotics WidowX robotic arm controlled by a Digilent ZedBoard provided with a Xilinx Zynq FPGA that computes the Inverse Kinematic.
Published: 2020

10. Modeling shallow landslides and root reinforcement: A review

Author: Murgia, Ilenia, Giadrossich, Filippo, Mao, Zhun, Cohen, Denis, Capra, Gian, Schwarz, Massimiliano, Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Botanique et Modélisation de l'Architecture des Plantes et des Végétations (UMR AMAP), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université de Montpellier (UM), New Mexico Institute of Mining and Technology [New Mexico Tech] (NMT), and Bern University of Applied Sciences (BFH)
Subjects: Stability assessment, [SDV.EE.ECO]Life Sciences [q-bio]/Ecology, environment/Ecosystems, Forest management, SD Forestry, Root reinforcement, Q Science (General), [SDV.BV.BOT]Life Sciences [q-bio]/Vegetal Biology/Botanics, [SDE.BE]Environmental Sciences/Biodiversity and Ecology, [SDV.BID.SPT]Life Sciences [q-bio]/Biodiversity/Systematics, Phylogenetics and taxonomy
Abstract: International audience; Slope Stability Models (SSMs) are valuable tools used as decision support in land management to mitigate catastrophic effects caused by rainfall-induced shallow landslides. In particular, SSMs incorporating the presence and influence of vegetation allow for the evaluation of how trees influence relative slope stability and how forest management could ensure the root reinforcement effect in space and time. By implementing empirical knowledge about complex mechanical and hydrological processes, SSMs have been realized by employing different modeling approaches and methods, becoming suitable for different contexts and scales of analysis. Recent SSMs increasingly consider vegetation both as a mechanism to counteract the triggering process of shallow landslides and as a manageable and modifiable tool for mitigating hazards. This review aims to analyze the state-of-the-art of SSMs applicable to vegetated slope areas, investigating those that consider root reinforcement and some of the most cited SSMs in the literature that neglect this effect instead. After classification and exposition on the spatial and temporal dimension of the analysis, modeling approaches, and complexity, we discuss the identification of the most suitable Slope Stability Model (SSM) for individual applications considering four fundamental aspects: modeling approaches, the analysis scale, and purpose, and the output data. Although all SSMs allow for risk analysis by quantifying the factor of safety, only a few allow for an accurate assessment of how changes in vegetation structure, due to the occurrence of natural and human disturbances, also affect the stability of a studied area. Such information is critical to identifying land management criteria to preserve and enhance the protection effect. The improvement of data collection and measurement techniques to obtain parameters for stability analysis required the development of new SSMs able to exploit the improved detail of information, thus allowing for increasingly accurate analyses.
Published: 2022
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11. In Vitro and In Silico Antimalarial Evaluation of FM-AZ, a New Artemisinin Derivative

Author: Ioannis Tsamesidis, Farnoush Mousavizadeh, Chinedu O. Egwu, Dionysia Amanatidou, Antonella Pantaleo, Françoise Benoit-Vical, Karine Reybier, Athanassios Giannis, Pharmacochimie et Biologie pour le Développement (PHARMA-DEV), Institut de Recherche pour le Développement (IRD)-Institut de Chimie de Toulouse (ICT), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT), International Hellenic University, Leipzig University, Alex Ekwueme Federal University Ndufu-Alike, Ikwo (AE-FUNAI), Laboratoire de chimie de coordination (LCC), Institut de Chimie de Toulouse (ICT), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS), and Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS)
Subjects: Novel artemisinin derivatives, novel artemisinin derivatives, in silico study, artemisinin resistance, ROS, LC-MS, Artemisinin resistance, parasitic diseases, General Engineering, General Earth and Planetary Sciences, [CHIM.COOR]Chemical Sciences/Coordination chemistry, ddc:610, General Environmental Science
Abstract: International audience; Artemisinin-based Combination Therapies (ACTs) are currently the frontline treatment against Plasmodium falciparum malaria, but parasite resistance to artemisinin (ART) and its derivatives, core components of ACTs, is spreading in the Mekong countries. In this study, we report the synthesis of several novel artemisinin derivatives and evaluate their in vitro and in silico capacity to counteract Plasmodium falciparum artemisinin resistance. Furthermore, recognizing that the malaria parasite devotes considerable resources to minimizing the oxidative stress that it creates during its rapid consumption of hemoglobin and the release of heme, we sought to explore whether further augmentation of this oxidative toxicity might constitute an important addition to artemisinins. The present report demonstrates, in vitro, that FM-AZ, a newly synthesized artemisinin derivative, has a lower IC50 than artemisinin in P. falciparum and a rapid action in killing the parasites. The docking studies for important parasite protein targets, PfATP6 and PfHDP, complemented the in vitro results, explaining the superior IC50 values of FM-AZ in comparison with ART obtained for the ART-resistant strain. However, cross-resistance between FM-AZ and artemisinins was evidenced in vitro.
Published: 2022

12. PathTracer: Understanding Response Time of Signal Processing Applications on Heterogeneous MPSoCs

Author: Claudio Rubattu, Francesca Palumbo, Shuvra S. Bhattacharyya, Maxime Pelcat, Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Institut d'Electronique et de Télécommunications de Rennes (IETR), Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Ecole Supérieure d'Electricité - SUPELEC (FRANCE)-Centre National de la Recherche Scientifique (CNRS), University of Maryland System, Institut Pascal (IP), Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA)-Institut national polytechnique Clermont Auvergne (INP Clermont Auvergne), Université Clermont Auvergne (UCA)-Université Clermont Auvergne (UCA), and European UnionEuropean Commission [783162, 732105]
Subjects: signal processing applications, processing latency, Computer Networks and Communications, MPSoC, Model-based design, design space exploration, [SPI]Engineering Sciences [physics], Hardware and Architecture, Media Technology, Computer Science (miscellaneous), Safety, Risk, Reliability and Quality, dataflow, Software, Information Systems
Abstract: In embedded and cyber-physical systems, the design of a desired functionality under constraints increasingly requires parallel execution of a set of tasks on a heterogeneous architecture. The nature of such parallel systems complicates the process of understanding and predicting performance in terms of response time. Indeed, response time depends on many factors related to both the functionality and the target architecture. State-of-the-art strategies derive response time by examining the operations required by each task for both processing and accessing shared resources. This procedure is often followed by the addition or elimination of potential interference due to task concurrency. However, such approaches require an advanced knowledge of the software and hardware details, rarely available in practice. This work presents an alternative “top-down” strategy, called PathTracer, aimed at understanding software response time and extending the cases in which it can be analyzed and estimated. PathTracer leverages on dataflow-based application representation and response time estimation of signal processing applications mapped on heterogeneous Multiprocessor Systems-on-a-Chip (MPSoCs). Experimental results demonstrate that PathTracer provides (i) information on the nature of the application (work-dominated, span-dominated, or balanced parallel), and (ii) response time modeling which can reach high accuracy when performed post-execution, leading to prediction errors with average and standard deviation under 5% and 3% respectively.
Published: 2021

13. Calibration of the liquid argon ionization response to low energy electronic and nuclear recoils with DarkSide-50

Author: The DarkSide Collaboration, Agnes, P., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Ave, M., Back, H. O., Batignani, G., Biery, K., Bocci, V., Bonivento, W. M., Bottino, B., Bussino, S., Cadeddu, M., Cadoni, M., Calaprice, F., Caminata, A., Canci, N., Caravati, M., Cariello, M., Carlini, M., Carpinelli, M., Catalanotti, S., Cataudella, V., Cavalcante, P., Cavuoti, S., Chepurnov, A., Cical��, C., Cocco, A. G., Covone, G., D'Angelo, D., Davini, S., De Candia, A., De Cecco, S., De Filippis, G., De Rosa, G., Derbin, A. V., Devoto, A., D'Incecco, M., Dionisi, C., Dordei, F., Downing, M., D'Urso, D., Fiorillo, G., Franco, D., Gabriele, F., Galbiati, C., Ghiano, C., Giganti, C., Giovanetti, G. K., Gorchakov, O., Goretti, A. M., Grobov, A., Gromov, M., Guan, M., Guardincerri, Y., Gulino, M., Hackett, B. R., Herner, K., Hosseini, B., Hubaut, F., Hungerford, E. V., Ianni, An., Ippolito, V., Keeter, K., Kendziora, C. L., Kochanek, I., Korablev, D., Korga, G., Kubankin, A., Kuss, M., La Commara, M., Lai, M., Li, X., Lissia, M., Longo, G., Machulin, I. N., Mapelli, L. P., Mari, S. M., Maricic, J., Martoff, C. J., Messina, A., Meyers, P. D., Milincic, R., Morrocchi, M., Mougeot, X., Muratova, V. N., Musico, P., Agasson, A. Navrer, Nozdrina, A. O., Oleinik, A., Ortica, F., Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Pelczar, K., Pelliccia, N., Picciau, E., Pocar, A., Pordes, S., Poudel, S. S., Pralavorio, P., Ragusa, F., Razeti, M., Razeto, A., Renshaw, A. L., Rescigno, M., Rode, J., Romani, A., Sablone, D., Samoylov, O., Sands, W., Sanfilippo, S., Savarese, C., Schlitzer, B., Semenov, D. A., Shchagin, A., Sheshukov, A., Skorokhvatov, M. D., Smirnov, O., Sotnikov, A., Stracka, S., Suvorov, Y., Tartaglia, R., Testera, G., Tonazzo, A., Unzhakov, E. V., Vishneva, A., Vogelaar, R. B., Wada, M., Wang, H., Wang, Y., Westerdale, S., Wojcik, M. M., Xiao, X., Yang, C., Zuzel, G., Agnes, P., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Ave, M., Back, H. O., Batignani, G., Biery, K., Bocci, V., Bonivento, W. M., Bottino, B., Bussino, S., Cadeddu, M., Cadoni, M., Calaprice, F., Caminata, A., Canci, N., Caravati, M., Cariello, M., Carlini, M., Carpinelli, M., Catalanotti, S., Cataudella, V., Cavalcante, P., Cavuoti, S., Chepurnov, A., Cicalò, C., Cocco, A. G., Covone, G., D’Angelo, D., Davini, S., De Candia, A., De Cecco, S., De Filippis, G., De Rosa, G., Derbin, A. V., Devoto, A., D’Incecco, M., Dionisi, C., Dordei, F., Downing, M., D’Urso, D., Fiorillo, G., Franco, D., Gabriele, F., Galbiati, C., Ghiano, C., Giganti, C., Giovanetti, G. K., Gorchakov, O., Goretti, A. M., Grobov, A., Gromov, M., Guan, M., Guardincerri, Y., Gulino, M., Hackett, B. R., Herner, K., Hosseini, B., Hubaut, F., Hungerford, E. V., Ianni, An., Ippolito, V., Keeter, K., Kendziora, C. L., Kochanek, I., Korablev, D., Korga, G., Kubankin, A., Kuss, M., La Commara, M., Lai, M., Li, X., Lissia, M., Longo, G., Machulin, I. N., Mapelli, L. P., Mari, S. M., Maricic, J., Martoff, C. J., Messina, A., Meyers, P. D., Milincic, R., Morrocchi, M., Mougeot, X., Muratova, V. N., Musico, P., Navrer Agasson, A., Nozdrina, A. O., Oleinik, A., Ortica, F., Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Pelczar, K., Pelliccia, N., Picciau, E., Pocar, A., Pordes, S., Poudel, S. S., Pralavorio, P., Ragusa, F., Razeti, M., Razeto, A., Renshaw, A. L., Rescigno, M., Rode, J., Romani, A., Sablone, D., Samoylov, O., Sands, W., Sanfilippo, S., Savarese, C., Schlitzer, B., Semenov, D. A., Shchagin, A., Sheshukov, A., Skorokhvatov, M. D., Smirnov, O., Sotnikov, A., Stracka, S., Suvorov, Y., Tartaglia, R., Testera, G., Tonazzo, A., Unzhakov, E. V., Vishneva, A., Vogelaar, R. B., Wada, M., Wang, H., Wang, Y., Westerdale, S., Wojcik, M. M., Xiao, X., Yang, C., Zuzel, G., University of Houston, Universidade de São Paulo = University of São Paulo (USP), Pacific Northwest National Laboratory (PNNL), Augustana University, Istituto Nazionale di Fisica Nucleare [Pisa] (INFN), Istituto Nazionale di Fisica Nucleare (INFN), Fermi National Accelerator Laboratory (Fermilab), Istituto Nazionale di Fisica Nucleare [Sezione di Roma 1] (INFN), Istituto Nazionale di Fisica Nucleare, Istituto Nazionale di Fisica Nucleare, Sezione di Cagliari (INFN, Sezione di Cagliari), Istituto Nazionale di Fisica Nucleare, Sezione di Genova (INFN, Sezione di Genova), Università degli Studi di Cagliari = University of Cagliari (UniCa), Princeton University, INFN Laboratori Nazionali del Gran Sasso, (INFN), Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), University of Naples Federico II = Università degli studi di Napoli Federico II, Virginia Tech [Blacksburg], D.V. Skobeltsyn Institute of Nuclear Physics (SINP), Lomonosov Moscow State University (MSU), Istituto Nazionale di Fisica Nucleare, Sezione di Napoli (INFN, Sezione di Napoli), Università degli Studi di Milano = University of Milan (UNIMI), Saint Petersburg Nuclear Physics Institute RAS, St Petersburg Nuclear Physics Institute, University of Massachusetts [Amherst] (UMass Amherst), University of Massachusetts System (UMASS), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Joint Institute for Nuclear Research (JINR), Institute of Molecular Genetics of National Research Centre «Kurchatov Institute» [Moscow, Russia], Russian Academy of Sciences [Moscow] (RAS), Institute of High Energy Physics [Beijing] (IHEP), Chinese Academy of Sciences [Changchun Branch] (CAS), Università degli Studi di Enna ' KORE ' = Kore University of Enna, Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Black Hills State University, Belgorod National Research University, University of California [Los Angeles] (UCLA), University of California (UC), Istituto Nazionale di Fisica Nucleare, Sezione di Roma 3 (INFN, Sezione di Roma 3), University of Hawai'i [Honolulu] (UH), Temple University [Philadelphia], Pennsylvania Commonwealth System of Higher Education (PCSHE), University of Hawai'i [Hilo], Laboratoire National Henri Becquerel (LNHB), Département Métrologie Instrumentation & Information (DM2I), Laboratoire d'Intégration des Systèmes et des Technologies (LIST (CEA)), Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Laboratoire d'Intégration des Systèmes et des Technologies (LIST (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Département d'instrumentation Numérique (DIN (CEA-LIST)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Belgorod National Research University, 308015 Belgorod, Russia, Università degli Studi di Perugia = University of Perugia (UNIPG), Università degli studi di Genova = University of Genoa (UniGe), Istituto Nazionale di Fisica Nucleare, Sezione di Catania (INFN), Università degli studi di Catania = University of Catania (Unict), University of California [Davis] (UC Davis), Istituto Nazionale di Fisica Nucleare, Sezione di Milano (INFN), Università degli Studi Roma Tre = Roma Tre University (ROMA TRE), Gran Sasso Science Institute (GSSI), Uniwersytet Jagielloński w Krakowie = Jagiellonian University (UJ), DarkSide, ANR-18-IDEX-0001,Université de Paris,Université de Paris(2018), Cicalo, C., D'Angelo, D., D'Incecco, M., D'Urso, D., Ianni, A., Agnes, P, Albuquerque, I, Alexander, T, Alton, A, Ave, M, Back, H, Batignani, G, Biery, K, Bocci, V, Bonivento, W, Bottino, B, Bussino, S, Cadeddu, M, Cadoni, M, Calaprice, F, Caminata, A, Canci, N, Caravati, M, Cariello, M, Carlini, M, Carpinelli, M, Catalanotti, S, Cataudella, V, Cavalcante, P, Cavuoti, S, Chepurnov, A, Cicalo, C, Cocco, A, Covone, G, D'Angelo, D, Davini, S, De Candia, A, De Cecco, S, De Filippis, G, De Rosa, G, Derbin, A, Devoto, A, D'Incecco, M, Dionisi, C, Dordei, F, Downing, M, D'Urso, D, Fiorillo, G, Franco, D, Gabriele, F, Galbiati, C, Ghiano, C, Giganti, C, Giovanetti, G, Gorchakov, O, Goretti, A, Grobov, A, Gromov, M, Guan, M, Guardincerri, Y, Gulino, M, Hackett, B, Herner, K, Hosseini, B, Hubaut, F, Hungerford, E, Ianni, A, Ippolito, V, Keeter, K, Kendziora, C, Kochanek, I, Korablev, D, Korga, G, Kubankin, A, Kuss, M, La Commara, M, Lai, M, Li, X, Lissia, M, Longo, G, Machulin, I, Mapelli, L, Mari, S, Maricic, J, Martoff, C, Messina, A, Meyers, P, Milincic, R, Morrocchi, M, Mougeot, X, Muratova, V, Musico, P, Navrer Agasson, A, Nozdrina, A, Oleinik, A, Ortica, F, Pagani, L, Pallavicini, M, Pandola, L, Pantic, E, Paoloni, E, Pelczar, K, Pelliccia, N, Picciau, E, Pocar, A, Pordes, S, Poudel, S, Pralavorio, P, Ragusa, F, Razeti, M, Razeto, A, Renshaw, A, Rescigno, M, Rode, J, Romani, A, Sablone, D, Samoylov, O, Sands, W, Sanfilippo, S, Savarese, C, Schlitzer, B, Semenov, D, Shchagin, A, Sheshukov, A, Skorokhvatov, M, Smirnov, O, Sotnikov, A, Stracka, S, Suvorov, Y, Tartaglia, R, Testera, G, Tonazzo, A, Unzhakov, E, Vishneva, A, Vogelaar, R, Wada, M, Wang, H, Wang, Y, Westerdale, S, Wojcik, M, Xiao, X, Yang, C, Zuzel, G, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), and Laboratoire d'Intégration des Systèmes et des Technologies (LIST)
Subjects: Physics - Instrumentation and Detectors, Physics::Instrumentation and Detectors, Electron, 01 natural sciences, 7. Clean energy, High Energy Physics - Experiment, electron recoil, High Energy Physics - Experiment (hep-ex), Recoil, n: irradiation, electron: recoil, ionization chamber, Ionization, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], Physics::Atomic Physics, nucleus recoil, Nuclear Experiment, nuclear instrumentation, nucleus: recoil, instrumentation, Physics, Range (particle radiation), irradiation, Instrumentation and Detectors (physics.ins-det), 3. Good health, Projection (relational algebra), Astrophysics - Instrumentation and Methods for Astrophysics, ionizing radiation, Calibration liquid argon ionization electronic and nuclear recoils dark matter, ionization: yield, FOS: Physical sciences, Electrons, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], DarkSide-50, Nuclear physics, ionization yield, numerical methods, 0103 physical sciences, Neutron, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], numerical calculations, 010306 general physics, Instrumentation and Methods for Astrophysics (astro-ph.IM), 010308 nuclear & particles physics, neutrons, Neutron radiation, time projection chamber: liquid argon, calibration, time projection chamber, liquid argon, WIMP: interaction, WIMP interaction, Yield (chemistry)
Abstract: DarkSide-50 has demonstrated the high potential of dual-phase liquid argon time projection chambers in exploring interactions of WIMPs in the GeV/c$^2$ mass range. The technique, based on the detection of the ionization signal amplified via electroluminescence in the gas phase, allows to explore recoil energies down to the sub-keV range. We report here on the DarkSide-50 measurement of the ionization yield of electronic recoils down to $\sim$180~eV$_{er}$, exploiting $^{37}$Ar and $^{39}$Ar decays, and extrapolated to a few ionization electrons with the Thomas-Imel box model. Moreover, we present a model-dependent determination of the ionization response to nuclear recoils down to $\sim$500~eV$_{nr}$, the lowest ever achieved in liquid argon, using \textit{in situ} neutron calibration sources and external datasets from neutron beam experiments., Comment: 11 pages, 12 figures, 1 table
Published: 2021

14. A comparative study on the efficiency of two Mycobacterium avium subsp. paratuberculosis (MAP)-derived lipopeptides of L3P and L5P as capture antigens in an in-house Milk ELISA test

Author: John P. Bannantine, Sepideh Hosseiniporgham, Christelle Ganneau, Franck Biet, Leonardo Antonio Sechi, Sylvie Bay, Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Infectiologie et Santé Publique (UMR ISP), Université de Tours (UT)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Chimie des Biomolécules - Chemistry of Biomolecules, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), United States Department of Agriculture (USDA), This research was funded by PON2017, grant code: DOT13299071 and CUP: j85D17000190001, and UNISS fondo per la ricerca 2020 to L.A.S., Università degli Studi di Sassari [Sassari] (UNISS), Université de Tours-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), and Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris]
Subjects: sheep, L3P, [SDV]Life Sciences [q-bio], Immunology, Mycobacterium paratuberculosis, Paratuberculosis, Milk elisa, Epitope, Article, Microbiology, 03 medical and health sciences, chemistry.chemical_compound, Antigen, Drug Discovery, medicine, antibodies, Pharmacology (medical), 030304 developmental biology, Pharmacology, 0303 health sciences, milk, biology, 030306 microbiology, bovine, Lipopeptide, biology.organism_classification, medicine.disease, Infectious Diseases, chemistry, Mycobacterium avium subsp. paratuberculosis, biology.protein, Medicine, ELISA, L5P, Antibody, Mycobacterium
Abstract: International audience; Mycobacterium avium subsp. paratuberculosis (MAP) surface-exposed lipopeptides could be specific capture-antigen molecules targeting antibodies against MAP, in milk, through ELISA. Previous studies have revealed that MAP strains, isolated from sheep (S) or cow (C), could produce specific lipopeptides, L3P or L5P, respectively. In this study, we used L3P and L5P as capture antigens in an in-house milk ELISA (H-MELISA) to assess how these antigens perform, in comparison with other ELISA tests, on well-defined milk samples from MAP-infected sheep. The overall positivity rates of H-MELISA via L3P and L5P varied by the source of milk samples, in which, at bulk-tank-milk (BTM) level, the majority of positive cases (63.83%) reacted more against L5P, whereas a predominant number (69.14%) of milk samples were more responsive against L3P at the individual level. To clarify whether the positivity status of milk samples in H-MELISA L3P/L5P were predictive of MAP strain-types (S/C), strain-typing was carried out using PCR IS1311-restriction enzyme analysis. Although the presence of three MAP strains (S/C/bison types) was detected among the milk samples, the C-type (46.67%) and S-type (75%) MAP strains were detected with higher incidence among BTMs and individual milk samples, respectively. However, further examination on the H-MELISA L3P/L5P-positivity pattern of each C/S-type-MAP sample revealed that some samples had a reverse reactivity against both L3P and L5P. These results could be the consequence of either cross-reactivity between L3P and L5P (due to the similarity in the structures of the two epitopes) or simply a within-herd mixed infection with MAP strains of C and S types. These findings suggest that lipopeptide antigens could contribute a diagnostic test with optimal performance, considering the diversity of MAP strains.
Published: 2021

15. Disease Behaviour During the Peri-Diagnostic Period in Patients with Suspected Interstitial Lung Disease: The STARLINER Study

Author: Onofre Moran-Mendoza, Monica Bengus, Stéphane Jouneau, Catharina C. Moor, Elisabeth Bendstrup, Klaus-Uwe Kirchgaessler, Syed Anees, Carlo Vancheri, Michael Henry, Frank Gilberg, Marlies S. Wijsenbeek, Mirela Mirt, Alessandro G. Fois, Claudia Valenzuela, Erasmus University Medical Center [Rotterdam] (Erasmus MC), Aarhus University Hospital, Universidad Autónoma de Madrid (UAM), Cork University Hospital, Institut de recherche en santé, environnement et travail (Irset), Université d'Angers (UA)-Université de Rennes (UR)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), CHU Pontchaillou [Rennes], Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Queen's University [Kingston, Canada], University of Windsor [Ca], F. Hoffmann-La Roche [Basel], Università degli studi di Catania = University of Catania (Unict), Ltd.Hoffmann-La Roche, Pulmonary Medicine, Universidad Autonoma de Madrid (UAM), Université d'Angers (UA)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Università degli Studi di Sassari [Sassari] (UNISS), and Università degli studi di Catania [Catania]
Subjects: Lung Diseases, Spirometry, 030213 general clinical medicine, medicine.medical_specialty, Vital capacity, Home spirometry, [SDV]Life Sciences [q-bio], Vital Capacity, Disease behaviour, Idiopathic pulmonary fibrosis, Interstitial lung disease, 03 medical and health sciences, FEV1/FVC ratio, 0302 clinical medicine, Internal medicine, medicine, Clinical endpoint, Humans, Pharmacology (medical), Original Research, medicine.diagnostic_test, business.industry, Peri-diagnostic period, General Medicine, Middle Aged, respiratory system, medicine.disease, Rheumatology, 3. Good health, respiratory tract diseases, Quartile, 030220 oncology & carcinogenesis, Interstitial, Lung Diseases, Interstitial, business
Abstract: Introduction Disease behaviour may guide diagnosis and treatment decisions in patients with interstitial lung disease (ILD). STARLINER aimed to characterise disease behaviour in patients with suspected ILD during the peri-diagnostic period using real-time home-based assessments. Methods STARLINER (NCT03261037) was an international, multicentre study. Patients ≥ 50 years old with suspected ILD were followed throughout the peri-diagnostic period, consisting of a pre-diagnostic period (from enrolment to diagnosis) and a post-diagnostic period (from diagnosis to treatment initiation). Study length was variable (≤ 18 months). The primary endpoint was time-adjusted semi-annual forced vital capacity (FVC) change measured during the peri-diagnostic period using daily home spirometry in patients with idiopathic pulmonary fibrosis (IPF). Secondary outcomes included changes in FVC (home spirometry) in patients with non-IPF ILD, changes in FVC (site spirometry), changes in physical functional capacity measured by daily home accelerometry and site 6-min walk distance (6MWD), and changes in patient-reported outcomes (PROs) in IPF or non-IPF ILD. Results Of the 178 patients enrolled in the study, 68 patients were diagnosed with IPF, 62 patients were diagnosed with non-IPF ILD, 9 patients received a non-ILD diagnosis and 39 patients did not receive a diagnosis. Technical and analytical issues led to problems in applying the prespecified linear regression model to analyse the home FVC data. Time-adjusted median (quartile [Q]1, Q3) semi-annual FVC change during the peri-diagnostic period measured using home and site spirometry, respectively, was – 147.7 (– 723.8, 376.2) ml and – 149.0 (– 314.6, 163.9) ml for IPF and 19.1 (– 194.9, 519.0) ml and – 23.4 (– 117.9, 133.5) ml in non-IPF ILD. A greater decline in steps per day was observed for IPF versus non-IPF ILD, whereas an increase in 6MWD was observed for patients with IPF versus a decline in 6MWD for patients with non-IPF ILD. No clear patterns of disease behaviour were observed for IPF versus non-IPF ILD for PROs. Conclusions Despite home spirometry being feasible for most patients and centres, technical and analytical challenges in the home-based assessments prevented firm conclusions regarding disease behaviour. This highlights that further optimisation of the technology and analysis methods is required before widespread implementation. Trial Registration NCT03261037. Supplementary Information The online version contains supplementary material available at 10.1007/s12325-021-01790-y.
Published: 2021

16. Phase transition of the 2-Choices dynamics on core–periphery networks

Author: André Nusser, Emanuele Natale, Emilio Cruciani, Giacomo Scornavacca, Universität Salzburg, Centre National de la Recherche Scientifique (CNRS), Combinatorics, Optimization and Algorithms for Telecommunications (COATI), Inria Sophia Antipolis - Méditerranée (CRISAM), Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)-COMmunications, Réseaux, systèmes Embarqués et Distribués (Laboratoire I3S - COMRED), Laboratoire d'Informatique, Signaux, et Systèmes de Sophia Antipolis (I3S), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA)-Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA)-Laboratoire d'Informatique, Signaux, et Systèmes de Sophia Antipolis (I3S), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA), Max Planck Institute for Informatics [Saarbrücken], Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Gran Sasso Science Institute (GSSI), Istituto Nazionale di Fisica Nucleare (INFN), Max-Planck-Institut für Informatik (MPII), Max-Planck-Gesellschaft, and Università degli Studi dell'Aquila (UNIVAQ)
Subjects: FOS: Computer and information sciences, Physics - Physics and Society, Consensus, Computer Networks and Communications, Computer science, FOS: Physical sciences, Class (philosophy), 0102 computer and information sciences, Physics and Society (physics.soc-ph), Topology, 01 natural sciences, Phase Transition, Theoretical Computer Science, Core-Periphery Structure, Metastability, 010104 statistics & probability, Simple (abstract algebra), Opinion Dynamics, 0101 mathematics, ComputingMilieux_MISCELLANEOUS, Rest (physics), Social and Information Networks (cs.SI), 2-Choices Dynamics, Process (computing), Computer Science - Social and Information Networks, Function (mathematics), Core (game theory), Social Networks, Computational Theory and Mathematics, 010201 computation theory & mathematics, Hardware and Architecture, Theory of computation, Voting behavior, [INFO.INFO-DC]Computer Science [cs]/Distributed, Parallel, and Cluster Computing [cs.DC]
Abstract: Consider the following process on a network: Each agent initially holds either opinion blue or red; then, in each round, each agent looks at two random neighbors and, if the two have the same opinion, the agent adopts it. This process is known as the 2-Choices dynamics and is arguably the most basic non-trivial opinion dynamics modeling voting behavior on social networks. Despite its apparent simplicity, 2-Choices has been analytically characterized only on restricted network classes---under assumptions on the initial configuration that establish it as a fast majority consensus protocol. In this work, we aim at contributing to the understanding of the 2-Choices dynamics by considering its behavior on a class of networks with core-periphery structure, a well-known topological assumption in social networks. In a nutshell, assume that a densely-connected subset of agents, the core, holds a different opinion from the rest of the network, the periphery. Then, depending on the strength of the cut between the core and the periphery, a phase-transition phenomenon occurs: Either the core's opinion rapidly spreads among the rest of the network, or a metastability phase takes place, in which both opinions coexist in the network for superpolynomial time. The interest of our result is twofold. On the one hand, by looking at the 2-Choices dynamics as a simplistic model of competition among opinions in social networks, our theorem sheds light on the influence of the core on the rest of the network, as a function of the core's connectivity toward the latter. On the other hand, we provide one of the first analytical results which shows a heterogeneous behavior of a simple dynamics as a function of structural parameters of the network. Finally, we validate our theoretical predictions with extensive experiments on real networks., Comment: A preliminary version of this work appeared in AAMAS 2018
Published: 2021

17. Dataflow-Functional High-Level Synthesis for Coarse-Grained Reconfigurable Accelerators

Author: Francesca Palumbo, Carlo Sau, Ruben Salvador, Maxime Pelcat, Luigi Raffo, Karol Desnos, Claudio Rubattu, Jocelyn Serot, Institut d'Électronique et des Technologies du numéRique (IETR), Nantes Université (NU)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS), University of Sassari, Department of Electrical and Electronic Engineering [University of Cagliari] (DIEE), University of Cagliari, Universidad Politécnica de Madrid (UPM), Institut Pascal (IP), SIGMA Clermont (SIGMA Clermont)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020]), 732105, H2020 LEIT Information and Communication Technologies, POR FESR 2014/20-ASSE I, PROSSIMO Project, 687698, HiPEAC Project (H2020), Université de Nantes (UN)-Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS), Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), SIGMA Clermont (SIGMA Clermont)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre National de la Recherche Scientifique (CNRS), and Université de Nantes (UN)-Université de Rennes 1 (UR1)
Subjects: HLS, General Computer Science, Design space exploration, Computer science, Dataflow, Functional Programming, MDC, 02 engineering and technology, Design Productivity, High-level synthesis, 0202 electrical engineering, electronic engineering, information engineering, Dataflow MoC, Coarse-Grained Reconfiguration, Field-programmable gate array, FPGA, Functional programming, Model of computation, 020208 electrical & electronic engineering, Control reconfiguration, Supercomputer, CAPH, 020202 computer hardware & architecture, Computer architecture, Control and Systems Engineering, Design Predictability, [SPI.SIGNAL]Engineering Sciences [physics]/Signal and Image processing
Abstract: International audience; Domain-specific acceleration is now a "must" for all the computing spectrum, going from high performance computing to embedded systems. Unfortunately, system specialization is by nature a nightmare from the design productivity perspective. Nevertheless, in contexts where kernels to be accelerated are intrinsically streaming oriented, the combination of dataflow models of computation with Coarse-Grained Reconfigurable (CGR) architectures can be particularly handful. In this paper we introduce a novel methodology to assemble and characterize virtually reconfigurable accelerators based on dataflow and functional programming principles, capable of addressing design productivity issues for CGR accelerators. The main advantage of the proposed methodology is accurate IP-level latency predictability improving Design Space Exploration (DSE) when compared to state-of-the-art High-Level Synthesis (HLS).
Published: 2019

18. Écouter, prononcer, s’écouter : les dispositifs nomades au service de l’oralité

Author: Caroline VENAILLE, Centre de recherches interdisciplinaires et transculturelles - UFC (EA 3224) (CRIT), Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Universitat de Barcelona (UB), Università degli Studi di Sassari [Sassari] (UNISS), Université de Perpignan Via Domitia (UPVD), Centre de Recherches Juridiques de l'Université de Franche-Comté - UFC (EA 3225) (CRJFC), Centre de recherches interdisciplinaires et transculturelles - UFC (UR 3224) (CRIT), Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), and Centre de Recherches Juridiques de l'Université de Franche-Comté - UFC (UR 3225) (CRJFC)
Subjects: [SHS.EDU]Humanities and Social Sciences/Education, ComputingMilieux_MISCELLANEOUS
Abstract: International audience
Published: 2021

19. Ecosystems

Author: Balzan, Mario V., Hassoun, Abed El Rahman, Aroua, Najet, Baldy, Virginie, Dagher, Magda Bou, Branquinho, Cristina, Dutay, Jean-Claude, Bour, Monia El, Médail, Frédéric, Mojtahid, Meryem, Morán-Ordóñez, Alejandra, Roggero, Pier Paolo, Heras, Sergio Rossi, Schatz, Bertrand, Vogiatzakis, Ioannis N., Zaimes, George N., Ziveri, Patrizia, Malta College of Arts, Science and Technology, Partenaires INRAE, National Center for Marine Sciences [Lebanon], National Council for Scientific Research = Conseil national de la recherche scientifique du Liban [Lebanon] (CNRS-L), Université Mohamed Khider de Biskra (BISKRA), Institut méditerranéen de biodiversité et d'écologie marine et continentale (IMBE), Avignon Université (AU)-Aix Marseille Université (AMU)-Institut de recherche pour le développement [IRD] : UMR237-Centre National de la Recherche Scientifique (CNRS), Faculty of Science, Saint-Joseph University, Beirut, Lebanon, Centre for Ecology, Evolution and Environmental Changes, Faculty of Sciences, University of Lisbon, Lisbon, Portugal, Laboratoire des Sciences du Climat et de l'Environnement [Gif-sur-Yvette] (LSCE), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Modélisation du climat (CLIM), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), National Institute of Marine Sciences and Technologies (INSTM), Carthage - Salammbô, Tunisia, University of Angers, Angers, France, Centre de Ciència i Tecnologia Forestal de Catalunya (CTFC), Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Department of Biological and Environmental Sciences (DiSTeBA), Uniersity of Salento, Salento, Italy, Centre d’Ecologie Fonctionnelle et Evolutive (CEFE), Université Paul-Valéry - Montpellier 3 (UPVM)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro - Montpellier SupAgro, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Open University of Cyprus, Nicosia, Cyprus, UNESCO Chair Con-E-Ect, International Hellenic University, Drama, Greece, Universitat Autònoma de Barcelona (UAB), Cramer W, Guiot J, and Marini K
Subjects: [SDE]Environmental Sciences, ComputingMilieux_MISCELLANEOUS
Abstract: International audience
Published: 2021

20. Ecosystems

Author: Balzan, Mario V., Hassoun, Abed El Rahman, Aroua, Najet, Baldy, Virginie, Dagher, Magda Bou, Branquinho, Cristina, Dutay, Jean-Claude, Bour, Monia El, Médail, Frédéric, Mojtahid, Meryem, Morán-Ordóñez, Alejandra, Roggero, Pier Paolo, Heras, Sergio Rossi, Schatz, Bertrand, Vogiatzakis, Ioannis N., Zaimes, George N., Ziveri, Patrizia, Malta College of Arts, Science and Technology, Partenaires INRAE, National Center for Marine Sciences [Lebanon], National Council for Scientific Research = Conseil national de la recherche scientifique du Liban [Lebanon] (CNRS-L), Université Mohamed Khider de Biskra (BISKRA), Institut méditerranéen de biodiversité et d'écologie marine et continentale (IMBE), Avignon Université (AU)-Aix Marseille Université (AMU)-Institut de recherche pour le développement [IRD] : UMR237-Centre National de la Recherche Scientifique (CNRS), Faculty of Science, Saint-Joseph University, Beirut, Lebanon, Centre for Ecology, Evolution and Environmental Changes, Faculty of Sciences, University of Lisbon, Lisbon, Portugal, Laboratoire des Sciences du Climat et de l'Environnement [Gif-sur-Yvette] (LSCE), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Modélisation du climat (CLIM), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), National Institute of Marine Sciences and Technologies (INSTM), Carthage - Salammbô, Tunisia, University of Angers, Angers, France, Centre de Ciència i Tecnologia Forestal de Catalunya (CTFC), Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Department of Biological and Environmental Sciences (DiSTeBA), Uniersity of Salento, Salento, Italy, Centre d’Ecologie Fonctionnelle et Evolutive (CEFE), Université Paul-Valéry - Montpellier 3 (UPVM)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro - Montpellier SupAgro, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Open University of Cyprus, Nicosia, Cyprus, UNESCO Chair Con-E-Ect, International Hellenic University, Drama, Greece, Universitat Autònoma de Barcelona (UAB), Cramer W, Guiot J, and Marini K
Subjects: [SDE]Environmental Sciences, ComputingMilieux_MISCELLANEOUS
Abstract: International audience
Published: 2021

21. Hydrology and Earth System Sciences

Author: Lassabatere, Laurent, Peyneau, Pierre-Emmanuel, Abou Najm, Majdi, Hammecker, Claude, Angulo-Jaramillo, Rafael, Yilmaz, Deniz, Pollacco, Joseph, Fernández-Gálvez, Jesús, Latorre, Borja, Moret-Fernández, David, Di Prima, Simone, Rahmati, Mehdi, Stewart, Ryan D., Équipe 5 - Impact des Aménagements et des Polluants sur les HYdrosystèmes (IAPHY), Laboratoire d'Ecologie des Hydrosystèmes Naturels et Anthropisés (LEHNA), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-École Nationale des Travaux Publics de l'État (ENTPE)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-École Nationale des Travaux Publics de l'État (ENTPE)-Centre National de la Recherche Scientifique (CNRS), Eau et Environnement (GERS-LEE ), Université Gustave Eiffel, Munzur University, Manaaki Whenua – Landcare Research [Lincoln], Universidad de Granada (UGR), Consejo Superior de Investigaciones Científicas [Spain] (CSIC), University of Sassari, University of Maragheh, Institute of Bio- and Geosciences [Jülich] (IBG), Forschungszentrum Jülich GmbH | Centre de recherche de Juliers, Helmholtz-Gemeinschaft = Helmholtz Association-Helmholtz-Gemeinschaft = Helmholtz Association, Virginia Polytechnic Institute and State University [Blacksburg], Department of Land, Air and Water Resources, University of California [Davis] (UC Davis), University of California-University of California, Laboratoire d'étude des Interactions Sol - Agrosystème - Hydrosystème (UMR LISAH), Institut de Recherche pour le Développement (IRD)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Universidad de Granada = University of Granada (UGR), Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), University of California (UC)-University of California (UC), Institut de Recherche pour le Développement (IRD)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro - Montpellier SupAgro, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), This research has been supported by the Agence Nationale de la Recherche (grant no. ANR-17-CE04-010)., ANR-17-CE04-0010,INFILTRON,Dispositif INFILTRON pour une évaluation des fonctions infiltration & filtration des sols urbains dans un contexte de gestion des eaux pluviales(2017), Université de Lyon-Université de Lyon-École Nationale des Travaux Publics de l'État (ENTPE)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-École Nationale des Travaux Publics de l'État (ENTPE)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Engineering Faculty, Civil Engineering Department, University of Tunceli, Tunceli, Turkey, parent, Departamento de Suelo y Agua, Estación Experimental de Aula Dei, Consejo Superior de Investigaciones Científicas [Madrid] (CSIC), Department of Agricultural Sciences, Desertification Research Centre, University of Sassari, Sassari, Italy, DEPARTMENT OF SOIL SCIENCE AND ENGINEERING FACULTY OF AGRICULTURE UNIVERSITY OF MARAGHEH IRN, Partenaires IRSTEA, Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA), and School of Plant and Environmental Sciences
Subjects: 0907 Environmental Engineering, Environmental Engineering, [SDU.STU.GC]Sciences of the Universe [physics]/Earth Sciences/Geochemistry, ddc:550, [SDE.BE]Environmental Sciences/Biodiversity and Ecology, 0406 Physical Geography and Environmental Geoscience, 0905 Civil Engineering
Abstract: Sorptivity is a parameter of primary importance in the study of unsaturated flow in soils. This hydraulic parameter is required to model water infiltration into vertical soil profiles. Sorptivity can be directly estimated from the soil hydraulic functions (water retention and hydraulic conductivity curves), using the integral formulation of Parlange (1975). However, calculating sorptivity in this manner requires the prior determination of the soil hydraulic diffusivity and its numerical integration between initial and final saturation degrees, which may be difficult in some situations (e.g., coarse soil with diffusivity functions that are quasi-infinite close to saturation). In this paper, we present a procedure to compute sorptivity using a scaling parameter, cp, that corresponds to the sorptivity of a unit soil (i.e., unit values for all parameters and zero residual water content) that is utterly dry at the initial state and saturated at the final state. The cp parameter was computed numerically and analytically for five hydraulic models: delta (i.e., Green and Ampt), Brooks and Corey, van Genuchten–Mualem, van Genuchten–Burdine, and Kosugi. Based on the results, we proposed brand new analytical expressions for some of the models and validated previous formulations for the other models. We also tabulated the output values so that they can easily be used to determine the actual sorptivity value for any case. At the same time, our numerical results showed that the relation between cp and the hydraulic shape parameters strongly depends on the chosen model. These results highlight the need for careful selection of the proper model for the description of the water retention and hydraulic conductivity functions when estimating sorptivity.
Published: 2021

22. Unmanned aerial systems-based monitoring of the eco-geomorphology of coastal dunes through spectral Rao's Q

Author: Manuele Bazzichetto, Jan Komárek, Simonetta Bagella, Alicia Teresa Rosario Acosta, Vítězslav Moudrý, Duccio Rocchini, Maria Laura Carranza, Marco Malavasi, Czech University of Life Sciences Prague (CZU), Ecosystèmes, biodiversité, évolution [Rennes] (ECOBIO), Université de Rennes (UR)-Institut Ecologie et Environnement (INEE), Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Observatoire des Sciences de l'Univers de Rennes (OSUR), Université de Rennes (UR)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Rennes 2 (UR2)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Rennes 2 (UR2)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Centre National de la Recherche Scientifique (CNRS), Alma Mater Studiorum Università di Bologna [Bologna] (UNIBO), Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Università degli Studi Roma Tre = Roma Tre University (ROMA TRE), Università degli Studi del Molise = University of Molise (UNIMOL), CA17134Horizon 2020 Framework Programme, H2020: 862480Interreg, Malavasi, Marco, Bazzichetto, Manuele, Komárek, Jan, Moudrý, Vítězslav, Rocchini, Duccio, Bagella, Simonetta, Acosta, Alicia T. R., Carranza, Maria L., Centre National de la Recherche Scientifique (CNRS)-Observatoire des Sciences de l'Univers de Rennes (OSUR)-Institut Ecologie et Environnement (INEE), Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES), University of Sassari, Università degli Studi Roma Tre, Università degli Studi del Molise (Unimol), Malavasi, M., Bazzichetto, M., Komarek, J., Moudry, V., Rocchini, D., Bagella, S., Acosta, A. T. R., and Carranza, M. L.
Subjects: 0106 biological sciences, Dune slope, 010504 meteorology & atmospheric sciences, NDVI, Management, Monitoring, Policy and Law, 010603 evolutionary biology, 01 natural sciences, Normalized Difference Vegetation Index, Coastal dunes, remote sensing, Rao's Q index, Eco-geomorphology, Habitat monitoring, 14. Life underwater, 0105 earth and related environmental sciences, Nature and Landscape Conservation, biodiversity, Ecology, 15. Life on land, Human pressure, 13. Climate action, Dune elevation, coastal dunes, dune elevation, dune slope, eco-geomorphology, habitat monitoring, human pressure, NDVI, Rao's Q index, spectral diversity UAS, Environmental science, Physical geography, [SDE.BE]Environmental Sciences/Biodiversity and Ecology, Spectral diversity UAS, Coastal dune
Abstract: International audience; Question: Does spectral diversity captured by unmanned aerial systems (UAS) provide reliable information for monitoring the eco-geomorphological integrity of Mediterranean coastal dune ecosystems? Can this information discriminate between two coastal areas with low (LP) and high (HP) human pressure? Location: Tyrrhenian coast, Central Italy. Methods: By processing UAS images, we derived the normalized difference vegetation index (NDVI) and topographic variables at high spatial resolution (0.5 m) for 150 m wide strips starting from the coastline inland on two representative coastal tracts under low and high human pressure. We mapped the sea–inland heterogeneity applying Rao's Q index to the plant biomass (NDVI) and geomorphology variables (elevation and slope). Since Rao's Q index can be calculated in a multidimensional space, we summarized the variability of these three variables into a single eco-geomorphological layer. We then inspected and compared how the Rao's Q index values for plant biomass, geomorphology and eco-geomorphology change as a func-tion of the distance from the sea between the two coastal sites. Results: Rao's Q heterogeneity values vary along the sea–inland gradient of well-preserved sites (LP). The maximum eco-geomorphological heterogeneity was found at intermediate distances from the sea and decreased toward the inner sector where the dune geomorphology was more stable and vegetation more homogeneously dis-tributed. Instead, Rao's Q heterogeneity values featured constant low values along the gradient on the HP site, highlighting a simplified eco-geomorphological gradient related to the high human pressure. Conclusions: Using UAS, the eco-geomorphological gradient of coastal dunes can be quantified at a very fine spatial resolution over management-relevant extents. Rao's Q index applied to sensing imagery successfully captured the differences in the eco-geomorphological heterogeneity along the sea–inland dune gradient and among sites with different levels of anthropic pressure. This approach supports frequent surveys and is particularly suitable for spatial monitoring of key coastal functions and services. © 2021 International Association for Vegetation Science.
Published: 2021

23. Information through different languages: a plurilingual informational competence

Author: Caroline Venaille, Encarnación Carrasco Perea, LInguistique et DIdactique des Langues Étrangères et Maternelles (LIDILEM), Université Grenoble Alpes (UGA), Centre de Recherches Juridiques de l'Université de Franche-Comté - UFC (EA 3225) (CRJFC), Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Université de Perpignan Via Domitia (UPVD), Università degli Studi di Sassari [Sassari] (UNISS), Universitat de Barcelona (UB), Centre de Recherches Juridiques de l'Université de Franche-Comté - UFC (UR 3225) (CRJFC), and Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS)
Subjects: multilingualism, [SHS.EDU]Humanities and Social Sciences/Education, 050801 communication & media studies, literacy, plurilinguisme, littératie, cross-comprehension, 0508 media and communications, intercompréhension, lcsh:P1-1091, Political science, mediation, [SHS.LANGUE]Humanities and Social Sciences/Linguistics, ComputingMilieux_MISCELLANEOUS, lcsh:LC8-6691, lcsh:Special aspects of education, 05 social sciences, 06 humanities and the arts, General Medicine, stratégies, 060202 literary studies, lcsh:Philology. Linguistics, strategies, 0602 languages and literature, médiation, Intercomprehension, Humanities
Abstract: Recevoir un contenu multimédia sur le web, considéré comme un espace d'information mondial, se caractérise par un paradoxe inhérent. La plupart du temps, l'accessibilité à l'information n'est pas pleinement exploitée. Face à l'abondance d'informations, moteurs de recherches et réseaux sociaux proposent aux usagers-lecteurs une sélection algorithmique de contenus adaptés à leur profil numérique (langue, géolocalisation, territoire, centre d'intérêts, etc.). Notre recherche qualitative renforcée par des données quantitatives se concentre sur trois aspects de la médiation : la réception, la production et l'intercompréhension. L'enquête ici présentée a été menée auprès de lecteurs, professionnels de l'information, en formation initiale ou continue, travaillant dans le sud de l'Europe, en Sardaigne ou en Catalogne. Cette étude recense ainsi les stratégies d'intercompréhension à fort potentiel informationnel et éducatif. Sur ces territoires où plusieurs langues sont en contact, la lecture en plusieurs langues favorise la comparaison et la confrontation d'informations différentes sur le plan culturel, politique et social. La connaissance de ces stratégies permet aux médiateurs, aux enseignants ou aux journalistes, de développer une compétence informationnelle plurilingue vis-à-vis des apprenants ou des récepteurs considérés comme des citoyens lecteurs. En devenant un "chercheur plurilingue" au lieu d'un "consommateur multilingue", les lecteurs numériques disposeraient de tous les outils nécessaires pour transformer les informations en connaissances. Receiving media content on the web, considered as a global information space, is typified by an inherent paradox. Most of the time, information accessibility is not fully exploited. Circles are mostly regulated by algorithm selection and by the use of translation and adaptation of the information to a target reader. Our qualitative research reinforced by quantitative data focuses on three aspects of mediation: reception, production, and intercomprehension. This investigation is contextualized in two complementary territories of Southern Europe: Sassari (Italy) and Barcelona (Spain). The study lists intercomprehension strategies with a strong informational and educational potential. Reading in several languages encourages the comparison and confrontation of information that is culturally, politically and socially different. Understanding those issues and knowing those strategies enables mediators, teachers or journalists, to develop a plurilingual informational competence towards learners or receptors seen as citizen readers. By becoming a “plurilingual researcher” instead of a “multilingual consumer”, digital readers would have all the necessary tools to transform information into knowledge.
Published: 2020

24. Mapping walkability. A subjective value theory approach

Author: Tanja Congiu, Alexis Tsoukiàs, Giovanna Fancello, Laboratoire d'analyse et modélisation de systèmes pour l'aide à la décision (LAMSADE), Université Paris Dauphine-PSL, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), University of Sassari, Tsoukiàs, Alexis, and Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS)
Subjects: Economics and Econometrics, Decision support system, [INFO.INFO-RO] Computer Science [cs]/Operations Research [cs.RO], capability approach, Strategy and Management, Geography, Planning and Development, 0211 other engineering and technologies, Public policy, 02 engineering and technology, Interpersonal communication, [INFO] Computer Science [cs], Management Science and Operations Research, Normative model of decision-making, 11. Sustainability, 0502 economics and business, decision maps, [INFO]Computer Science [cs], 050207 economics, ComputingMilieux_MISCELLANEOUS, preferences, walkability, 021103 operations research, business.industry, 05 social sciences, multi-attribute value theory, Usability, [INFO.INFO-RO]Computer Science [cs]/Operations Research [cs.RO], Environmental economics, Multiple-criteria decision analysis, multi-criteria decision analysis, Walkability, Capability approach, Statistics, Probability and Uncertainty, business, Psychology
Abstract: The analysis of urban walkability has been extensively explored in the last decades. Despite this growing attention, there is a lack of studies attentive on how citizens' values, individual abilities and urban environment favour or hinder the propensity to walk. Hence, there is a need to explore how preferences and values of citizens vary in space in order to design walkability policies able to improve the capability set of citizens. In this perspective, the design of spatial decision tools aimed to plann public policies for the development of walkable cities needs further investigation. We propose a Multiple Criteria Decision Analysis (MCDA) method aimed to elaborate walkability decision maps for different groups of citizens that reflect their capability to walk in the urban environment. We tested the method in the city of Alghero (Italy). First, we analysed walkability under a normative model named CAWS; then we made a survey with 358 participants in order to study the driving values that influence their choice to walk and finalised to build an evaluation model attentive to individual differences. Cluster analysis was employed to group citizens into 11 groups based on their sociodemographic characteristics and preferences on spatial criteria of walkability. Finally, by integrating GIS with MCDA we built a set of decision maps representative of the walkability of the 11 groups of citizens. Results highlight the importance of citizens’ values for policy design, allow the interpersonal comparison among individuals and group preferences and give new suggestions for the formulation of walkability oriented urban policies. Moreover, the results confirm the usability of the general method as a decision support tool supporting the design of urban policies.
Published: 2020

25. ‘Candidatus Liberibacter solanacearum’ distribution and diversity in Scotland and the characterisation of novel haplotypes from Craspedolepta spp. (Psyllidae: Aphalaridae)

Author: Mairi Carnegie, Yvonne M. Arnsdorf, Zoë Lawrence, Emma Back, Siobhán Madden, Fiona Highet, William Billaud, Silvia Carboni, David Kenyon, Jason Sumner-Kalkun, Building Research Establishment (BRE/Edinburgh), University of Edinburgh, University of Glasgow, University of Sassari, Génétique et Amélioration des Fruits et Légumes (GAFL), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Scottish Government RRL/001/14, European Project: 8502369(1985), and Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS)
Subjects: Crops, Agricultural, 0106 biological sciences, Anthriscus sylvestris, [SDV.BIO]Life Sciences [q-bio]/Biotechnology, Molecular biology, lcsh:Medicine, Microbial communities, Microbiology, 01 natural sciences, DNA barcoding, Article, Microbial ecology, Hemiptera, Liberibacter, Botany, Animals, lcsh:Science, Solanaceae, Plant Diseases, 2. Zero hunger, Multidisciplinary, Rubiaceae, Ecology, Bacteria, Environmental microbiology, biology, Chenopodium, lcsh:R, Haplotype, Urtica dioica, Biodiversity, biology.organism_classification, Aphalaridae, 010602 entomology, Haplotypes, Scotland, Trioza, lcsh:Q, Plant sciences, Weed, Microbial genetics, Zoology, Entomology, Apiaceae, 010606 plant biology & botany
Abstract: The phloem limited bacterium ‘Candidatus Liberibacter solanacearum’ (Lso) is associated with disease in Solanaceous and Apiaceous crops. This bacterium has previously been found in the UK in Trioza anthrisci, but its impact on UK crops is unknown. Psyllid and Lso diversity and distribution among fields across the major carrot growing areas of Scotland were assessed using real-time PCR and DNA barcoding techniques. Four Lso haplotypes were found: C, U, and two novel haplotypes. Lso haplotype C was also found in a small percentage of asymptomatic carrot plants (9.34%, n = 139) from a field in Milnathort where known vectors of this haplotype were not found. This is the first report of Lso in cultivated carrot growing in the UK and raises concern for the carrot and potato growing industry regarding the potential spread of new and existing Lso haplotypes into crops. Trioza anthrisci was found present only in sites in Elgin, Moray with 100% of individuals harbouring Lso haplotype C. Lso haplotype U was found at all sites infecting Trioza urticae and at some sites infecting Urtica dioica with 77.55% and 24.37% average infection, respectively. The two novel haplotypes were found in Craspedolepta nebulosa and Craspedolepta subpunctata and named Cras1 and Cras2. This is the first report of Lso in psyllids from the Aphalaridae. These new haplotypes were most closely related to Lso haplotype H recently found in carrot and parsnip. Lso was also detected in several weed plants surrounding carrot and parsnip fields. These included two Apiaceous species Aegropodium podagraria (hap undetermined) and Anthriscus sylvestris (hap C); one Gallium sp. (Rubiaceae) (hap undetermined); and Chenopodium album (Amaranthaceae) (hap undetermined).
Published: 2020

26. First Mediterranean Assessment Report – Chapter 4: Ecosystems

Author: Balzan, Mario V., Hassoun, Abed El Rahman, Aroua, Najet, Baldy, Virginie, Dagher, Magda Bou, Branquinho, Cristina, Dutay, Jean-Claude, Bour, Monia El, Médail, Frédéric, Mojtahid, Meryem, Morán-Ordóñez, Alejandra, Roggero, Pier Paolo, Heras, Sergio Rossi, Schatz, Bertrand, Vogiatzakis, Ioannis N., Zaimes, George N., Ziveri, Patrizia, Malta College of Arts, Science and Technology, Partenaires INRAE, National Center for Marine Sciences [Lebanon], National Council for Scientific Research = Conseil national de la recherche scientifique du Liban [Lebanon] (CNRS-L), Université Mohamed Khider de Biskra (BISKRA), Institut méditerranéen de biodiversité et d'écologie marine et continentale (IMBE), Avignon Université (AU)-Aix Marseille Université (AMU)-Institut de recherche pour le développement [IRD] : UMR237-Centre National de la Recherche Scientifique (CNRS), Université Saint-Joseph de Beyrouth (USJ), Centre for Ecology, Evolution and Environmental Changes, Faculty of Sciences, University of Lisbon, Lisbon, Portugal, Laboratoire des Sciences du Climat et de l'Environnement [Gif-sur-Yvette] (LSCE), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Modélisation du climat (CLIM), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), National Institute of Marine Sciences and Technologies (INSTM), Carthage - Salammbô, Tunisia, University of Angers, Angers, France, Centre de Ciència i Tecnologia Forestal de Catalunya (CTFC), Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Department of Biological and Environmental Sciences (DiSTeBA), Uniersity of Salento, Salento, Italy, Centre d’Ecologie Fonctionnelle et Evolutive (CEFE), Université Paul-Valéry - Montpellier 3 (UPVM)-École Pratique des Hautes Études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro - Montpellier SupAgro, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Open University of Cyprus, Nicosia, Cyprus, UNESCO Chair Con-E-Ect, International Hellenic University, Drama, Greece, Universitat Autònoma de Barcelona (UAB), Cramer W, Guiot J, and Marini K
Subjects: [SDE]Environmental Sciences
Abstract: International audience
Published: 2020

27. Syk Inhibitors: New Computational Insights into Their Intraerythrocytic Action in Plasmodium falciparum Malaria

Author: Marchetti, Giuseppe, Dessì, Alessandro, Dallocchio, Roberto, Tsamesidis, Ioannis, Pau, Maria Carmina, Turrini, Francesco Michelangelo, Pantaleo, Antonella, Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Istituto di Chimica Biomolecolare = Institute of Biomolecular Chemistry (ICB), National Research Council of Italy | Consiglio Nazionale delle Ricerche (CNR), Pharmacochimie et Biologie pour le Développement (PHARMA-DEV), Institut de Recherche pour le Développement (IRD)-Institut de Chimie de Toulouse (ICT), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT), and Università degli studi di Torino = University of Turin (UNITO)
Subjects: [SDV]Life Sciences [q-bio], antimalarial drugs, molecular docking, band 3, molecular dynamics, red blood cells
Abstract: International audience; Resistance to antimalarial drugs has spread rapidly over the past few decades. The WHO recommends artemisinin-based combination therapies for the treatment of uncomplicated malaria, but unfortunately these approaches are losing their efficacy in large areas of Southeast Asia. In 2016, artemisinin resistance was confirmed in 5 countries of the Greater Mekong subregion. We focused our study on Syk inhibitors as antimalarial drugs. The Syk protein is present in human erythrocytes, and the membrane of protein band 3 is its major target following activation by oxidant stress. Tyr phosphorylation of band 3 occurs during P. falciparum growth, leading to the release of microparticles containing hemicromes and structural weakening of the host cell membrane, simplifying merozoite reinfection. Syk inhibitors block these events by interacting with the Syk protein’s catalytic site. We performed in vitro proteomics and in silico studies and compared the results. In vitro studies were based on treatment of the parasite’s cellular cultures with different concentrations of Syk inhibitors, while proteomics studies were focused on the Tyr phosphorylation of band 3 by Syk protein with the same concentrations of drugs. In silico studies were based on different molecular modeling approaches in order to analyze and optimize the ligand–protein interactions and obtain the highest efficacy in vitro. In the presence of Syk inhibitors, we observed a marked decrease of band 3 Tyr phosphorylation according to the increase of the drug’s concentration. Our studies could be useful for the structural optimization of these compounds and for the design of novel Syk inhibitors in the future.
Published: 2020

28. Challenges and innovations for improving the sustainability of European agroforestry systems of high nature and cultural value: stakeholder perspectives

Author: Tibor Hartel, Valérie Viaud, Fernando Pulido, Paul J. Burgess, Anastasia Pantera, Antonello Franca, Gerardo Moreno, Anna Varga, Stéphanie Aviron, Josep Crous-Duran, Gioavanna Seddaiu, Staffan Berg, Joana Amaral Paulo, Victor Rolo, Jaconette Mirck, Claudine Thenail, João H.N. Palma, Universidad de Extremadura - University of Extremadura (UEX), INDEHESA, Forestry School, Babes-Bolyai University [Cluj-Napoca] (UBB), Biodiversité agroécologie et aménagement du paysage (UMR BAGAP), Ecole supérieure d'Agricultures d'Angers (ESA)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-INSTITUT AGRO Agrocampus Ouest, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), European Forest Institute (EFI), Universidade de Lisboa = University of Lisbon (ULISBOA), CNR-ISPAAM, Istituto per il Sistema Produzione Animale in Ambiente Mediterraneo, National Research Council of Italy | Consiglio Nazionale delle Ricerche (CNR), EntoNative GmbH (Tenetrio), MV Agroecology Research Centre, Agricultural University of Athens, Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), MTA Centre for Ecological Research [Tihany], Hungarian Academy of Sciences (MTA), Sol Agro et hydrosystème Spatialisation (SAS), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-INSTITUT AGRO Agrocampus Ouest, Cranfield University, Regional government of Extremadura: 'Talento' fellowship (TA18022), European Project: 613520,EC:FP7:KBBE,FP7-KBBE-2013-7-single-stage,AGFORWARD(2014), University of Extremadura, AGROCAMPUS OUEST, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Ecole supérieure d'Agricultures d'Angers (ESA)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Universidade de Lisboa (ULISBOA), Consiglio Nazionale delle Ricerche [Roma] (CNR), University of Sassari, and Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)
Subjects: Value (ethics), Health (social science), Mosaic-like agriculture, 010504 meteorology & atmospheric sciences, Sociology and Political Science, media_common.quotation_subject, Geography, Planning and Development, Participatory action research, 010501 environmental sciences, Management, Monitoring, Policy and Law, 01 natural sciences, 12. Responsible consumption, Regional-based solution, 11. Sustainability, Production (economics), 0105 earth and related environmental sciences, Nature and Landscape Conservation, media_common, 2. Zero hunger, Sustainable development, Global and Planetary Change, Ecology, Agroforestry, Stakeholder, Silvopastoral systems, 15. Life on land, Adaptive policy, Participative innovation, European survey, 13. Climate action, Sustainability, [SDE]Environmental Sciences, Business, Landscape ecology, Diversity (politics)
Abstract: International audience; Traditional forms of agroforestry are often recognized as exemplar systems that successfully integrate food production, biodiversity conservation and high cultural values. However many traditional agroforestry systems in Europe are in decline or are threatened and the perspectives of local stakeholders on the production, management, socio-economic, and environmental dimensions of such systems are not fully understood. To fill this gap, we present results of participatory research performed with ten stakeholder groups (SG) across Europe to search for solutions to improve the economic and ecological sustainability of High Nature and Cultural Value agroforestry systems (HNCV agroforestry). Stakeholders included both users and beneficiaries of the HNCV agroforestry. First, SGs held open discussions (227 participants) to identify major challenges for the long-term sustainability of HNCV agroforestry. Challenges were classified into production, management, socio-economic and the environment categories. Second, they responded to structured questionnaires (120 respondents) that explored the positive and negative perceptions of 45 possible attributes of HNCV agroforestry. Third, innovative solutions were identified by individual and group discussions to address the four categories of challenge. Challenges were mostly identified for the management and socio-economic categories, but several challenges concerning production and environment were also pinpointed. Besides, solutions matched poorly with the challenges identified, and, while challenges were at some extent common across countries, solutions to address them were more case-specific. The successful implementation of these solutions requires an in-depth understanding of the diversity of socio-cultural and natural contexts of the HNCV agroforestry systems and building bottom-up proposals and collective actions based on this understanding. The sustainability of HNCV agroforestry would be benefited by providing farmers and managers with a financial advantage from the high nature and cultural value of these systems.
Published: 2020

29. Syk Kinase Inhibitors Synergize with Artemisinins by Enhancing Oxidative Stress in Plasmodium Falciparum-Parasitized Erythrocytes

Author: Maria Carmina Pau, Antonella Pantaleo, Francesco Michelangelo Turrini, Patrizia Virdis, Claudio Fozza, Françoise Nepveu, Philip S. Low, Giuseppe Marchetti, Karine Reybier, Ioannis Tsamesidis, Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Pharmacochimie et Biologie pour le Développement (PHARMA-DEV), Institut de Recherche pour le Développement (IRD)-Institut de Chimie de Toulouse (ICT), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT), Purdue University [West Lafayette], and Università degli studi di Torino = University of Turin (UNITO)
Subjects: 0301 basic medicine, Physiology, [SDV]Life Sciences [q-bio], hemichromes, Clinical Biochemistry, Plasmodium falciparum, Oxidative phosphorylation, Pharmacology, artemisinin derivatives, medicine.disease_cause, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, parasitic diseases, medicine, oxidative stress, Artemisinin, Molecular Biology, Hemichrome, chemistry.chemical_classification, reactive oxygen species, Reactive oxygen species, syk kinase inhibitors, biology, Chemistry, lcsh:RM1-950, Cell Biology, biology.organism_classification, 030104 developmental biology, lcsh:Therapeutics. Pharmacology, 030220 oncology & carcinogenesis, Toxicity, Hemoglobin, Oxidative stress, medicine.drug
Abstract: International audience; Although artemisinin-based combination therapies (ACTs) treat Plasmodium falciparum malaria effectively throughout most of the world, the recent expansion of ACT-resistant strains in some countries of the Greater Mekong Subregion (GMS) further increased the interest in improving the effectiveness of treatment and counteracting resistance. Recognizing that (1) partially denatured hemoglobin containing reactive iron (hemichromes) is generated in parasitized red blood cells (pRBC) by oxidative stress, (2) redox-active hemichromes have the potential to enhance oxidative stress triggered by the parasite and the activation of artemisinin to its pharmaceutically active form, and (3) Syk kinase inhibitors block the release of membrane microparticles containing hemichromes, we hypothesized that increasing hemichrome content in parasitized erythrocytes through the inhibition of Syk kinase might trigger a virtuous cycle involving the activation of artemisinin, the enhancement of oxidative stress elicited by activated artemisinin, and a further increase in hemichrome production. We demonstrate here that artemisinin indeed augments oxidative stress within parasitized RBCs and that Syk kinase inhibitors further increase iron-dependent oxidative stress, synergizing with artemisinin in killing the parasite. We then demonstrate that Syk kinase inhibitors achieve this oxidative enhancement by preventing parasite-induced release of erythrocyte-derived microparticles containing redox-active hemichromes. We also observe that Syk kinase inhibitors do not promote oxidative toxicity to healthy RBCs as they do not produce appreciable amounts of hemichromes. Since some Syk kinase inhibitors can be taken daily with minimal side effects, we propose that Syk kinase inhibitors could evidently contribute to the potentiation of ACTs.
Published: 2020
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30. Oxidation of Erythrocytes Enhance the Production of Reactive Species in the Presence of Artemisinins

Author: Tsamesidis, Ioannis, Pério, Pierre, Pantaleo, Antonella, Reybier, Karine, Pharmacochimie et Biologie pour le Développement (PHARMA-DEV), Institut de Recherche pour le Développement (IRD)-Institut de Chimie de Toulouse (ICT), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT), and Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS)
Subjects: Male, Erythrocytes, Iron, [SDV]Life Sciences [q-bio], hydrogen peroxide, Heme, Deferoxamine, phenylhydrazine, Article, lcsh:Chemistry, Hemoglobins, Superoxides, Humans, lcsh:QH301-705.5, Methemoglobin, superoxide radicals, oxidized erythrocytes, Middle Aged, Oxidants, Artemisinins, LC-MS, Oxidative Stress, artemisinin, lcsh:Biology (General), lcsh:QD1-999, Oxyhemoglobins, Female, Reactive Oxygen Species, Oxidation-Reduction
Abstract: International audience; In red blood cells, hemoglobin iron represents the most plausible candidate to catalyze artemisinin activation but the limited reactivity of iron bound to hemoglobin does not play in favor for its direct involvement. Denatured hemoglobin appears a more likely candidate for artemisinin redox activation because it is expected to contain reactive iron and it has been described to release free heme and/or iron in erythrocyte. The aim of our study is to investigate, using three different methods: fluorescence, electron paramagnetic resonance and liquid chromatography coupled to mass spectrometry, how increasing the level of accessible iron into the red blood cells can enhance the reactive oxygen species (ROS) production derived from artemisinin. The over-increase of iron was achieved using phenylhydrazine, a strong oxidant that causes oxidative stress within erythrocytes, resulting in oxidation of oxyhemoglobin and leading to the formation of methemoglobin, which is subsequently converted into irreversible hemichromes (iron (III) compounds). Our findings confirmed, using the iron III chelator, desferrioxamine, the indirect participation of iron (III) compounds in the activation process of artemisinins. Furthermore, in strong reducing conditions, the activation of artemisinin and the consequent production of ROS was enhanced. In conclusion, we demonstrate, through the measurement of intra-erythrocytic superoxide and hydrogen peroxide production using various methods, that artemisinin activation can be drastically enhanced by pre-oxidation of erythrocytes.
Published: 2020

31. MEDLEM database, a data collection on large Elasmobranchs in the Mediterranean and Black seas

Author: Mancusi, Cecilia, Baino, Romano, Fortuna, Caterina, De Sola, Luis Gil, Morey, Gabriel, Bradai, Mohamed Nejmeddine, Kallianotis, Argyrios, Soldo, Alen, Hemida, Farid, Saad, Adib Ali, Dimech, Mark, Peristeraki, Panagiota, Bariche, Michel, Clo, Simona, De Sabata, Eleonora, Castellano, Laura, Garibaldi, Fulvio, Lanteri, Luca, Tinti, Fausto, Pais, Antonio, SPERONE, Emilio, Micarelli, Primo, Poisson, Francois, Sion, Letizia, Carlucci, Roberto, Cebrian-Menchero, Daniel, Seret, Bernard, Ferretti, Francesco, El-Far, Alaa, Saygu, Ismet, Shakman, Esmail A., Bartoli, Alex, Guallart, Javier, Damalas, Dimitrios, Megalofonou, Persefoni, Vacchi, Marino, Colloca, Francesco, Bottaro, Massimiliano, di Sciara, Giuseppe Notarbartolo, Follesa, Maria Cristina, Cannas, Rita, Kabasakal, Hakan, Zava, Bruno, Cavlan, Graziella, Jung, Armelle, Abudaya, Mohammed, Kolitari, Jerina, Barash, Adi, Joksimovic, Aleksandar, Cetkovic, Ilija, Marceta, Bojan, Gonzalez Vilas, Luis, TIRALONGO, Francesco, Giovos, Ioannis, Bargnesi, Filippo, Lelli, Stefano, Barone, Monica, Moro, Stefano, Mazzoldi, Carlotta, Charis, Charilaou, Abella, Alvaro Juan, Serena, Fabrizio, University of Split, Hellenic Center for Marine Research (HCMR), American University of Beirut [Beyrouth] (AUB), Alma Mater Studiorum Università di Bologna [Bologna] (UNIBO), Department of Biology, Ecology and Earth Sciences [Arcavacata di Rende] (DiBEST), Università della Calabria [Arcavacata di Rende] (Unical), MARine Biodiversity Exploitation and Conservation (UMR MARBEC), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Institut de Recherche pour le Développement (IRD), Institut de Recherche pour le Développement (IRD), Stazione Zoologica Anton Dohrn (SZN), Universita degli Studi di Cagliari [Cagliari], Agricultural University of Tirana, Département Aérodynamique Energétique et Propulsion (DAEP), Institut Supérieur de l'Aéronautique et de l'Espace (ISAE-SUPAERO), University of Catania [Italy], Centre de Formation et de Recherche sur les Environnements Méditérranéens (CEFREM), Université de Perpignan Via Domitia (UPVD)-Centre National de la Recherche Scientifique (CNRS), Istituto Superiore per la Protezione e la Ricerca Ambientale (ISPRA), Instituto Espagňol de Oceanografia (IEO), Consejo Superior de Investigaciones Científicas [Madrid] (CSIC), SOCIB Balearic Islands Coastal Ocean Observing and Forecasting System, Institut National des Sciences et Technologies de la Mer [Salammbô] (INSTM), National Agricultural Research Foundation (NAGREF), Université des Sciences et de la Technologie Houari Boumediene = University of Sciences and Technology Houari Boumediene [Alger] (USTHB), Tishreen University, Hellenic Centre for Marine Research (HCMR), Università degli studi di Genova = University of Genoa (UniGe), Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Institut de Recherche pour le Développement (IRD)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Università degli studi di Bari Aldo Moro = University of Bari Aldo Moro (UNIBA), Regional Activity Centre for Specially Protected Areas (RAC/SPA), Hopkins Marine Station [Stanford], Stanford University, Cukurova University, University of Tripoli - University Al Fateh, SUBMON - Marine Environmental Services [SPAIN], Universitat de València (UV), National Technical University of Athens [Athens] (NTUA), Istituto di Science Marine (ISMAR ), National Research Council of Italy | Consiglio Nazionale delle Ricerche (CNR), Tethys Research Institute [ITALIE], Università degli Studi di Cagliari = University of Cagliari (UniCa), Nature Trust (Malta), University of Haifa [Haifa], University of Montenegro (UCG), Zavod za ribištvo Slovenije (ZZRS), University of Vigo [ Pontevedra], Marine & Environmental Research Lab Ltd (MER), Università Politecnica delle Marche [Ancona] (UNIVPM), Université de Perpignan Via Domitia (UPVD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), FAO Fisheries Division (FAO), Food and Agriculture Organization of the United Nations [Rome, Italie] (FAO), Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome] (UNIROMA), Università degli Studi di Padova = University of Padua (Unipd), Institute for Biological Resources and Marine Biotechnology (IRBIM), Mancusi C., Baino R., Fortuna C., De Sola L.G., Morey G., Bradai M.N., Kallianotis A., Soldo A., Hemida F., Saad A.A., Dimech M., Peristeraki P., Bariche M., Clo S., De Sabata E., Castellano L., Garibaldi F., Lanteri L., Tinti F., Pais A., Sperone E., Micarelli P., Poisson F., Sion L., Carlucci R., Cebrian-Menchero D., Seret B., Ferretti F., El-Far A., Saygu I., Shakman E.A., Bartoli A., Guallart J., Damalas D., Megalofonou P., Vacchi M., Colloca F., Bottaro M., Di Sciara G.N., Follesa M.C., Cannas R., Kabasakal H., Zava B., Cavlan G., Jung A., Abudaya M., Kolitari J., Barash A., Joksimovic A., Cetkovic I., Marceta B., Vilas L.G., Tiralongo F., Giovos I., Bargnesi F., Lelli S., Barone M., Moro S., Mazzoldi C., Charis C., Abella A.J., and Serena F.
Subjects: Bycatch, databases, geographical distribution, large elasinobranchs, Mediterranean and Black seas, sharks, 0106 biological sciences, Mediterranean climate, 2417.05 Biología Marina, 2510.01 Oceanografía Biológica, large elasmobranchs, cetorhinus-maximus gunnerus, Oceanography, computer.software_genre, 01 natural sciences, Basking shark, Pesquerías, Thresher shark, 1st records, biology, Database, conservation, 04 agricultural and veterinary sciences, carcharhinidae, Geography, Mediterranean and black sea, coast, basking shark, Large elasmobranch, carcharodon-carcharias linnaeus, Environmental Engineering, [SDE.MCG]Environmental Sciences/Global Changes, Fishing, Sede Central IEO, Aquatic Science, plumbeus chondrichthyes, biology.animal, [SDV.BA.ZV]Life Sciences [q-bio]/Animal biology/Vertebrate Zoology, by-catch, 14. Life underwater, Ecology, Evolution, Behavior and Systematics, 010604 marine biology & hydrobiology, biology.organism_classification, lamniformes cetorhinidae, Great white shark, Butterfly ray, 040102 fisheries, 0401 agriculture, forestry, and fisheries, Conservation status, [SDE.BE]Environmental Sciences/Biodiversity and Ecology, computer
Abstract: The Mediterranean Large Elasmobranchs Monitoring (MEDLEM) database contains more than 3,000 records (with more than 4,000 individuals) of large elasmobranch species from 21 different countries around the Mediterranean and Black seas, observed from 1666 to 2017. The principal species included in the archive are the devil ray (1,868 individuals), the basking shark (935 individuals), the blue shark (622 individuals), and the great white shark (342 individuals). In the last decades, other species such as the thresher shark (187 individuals), the shortfin mako (180 individuals), and the spiny butterfly ray (138) were reported with increasing frequency. This was possibly due to increased public awareness on the conservation status of sharks, and the consequent development of new monitoring programs. MEDLEM does not have homogeneous reporting coverage throughout the Mediterranean and Black seas and it should be considered as a database of observed species presence. Scientific monitoring efforts in the south-eastern Mediterranean and Black seas are generally lower than in the northern sectors and the absence of some species in our database does not imply their actual absence in these regions. However,the available data allowed us to analyse the frequency and spatial distribution of records, the size frequencies for a few selected species, the overall area coverage, and which species are involved as bycatch by different fishing gears., Sí
Published: 2020

32. Intraspecific variability in membrane proteome, cell growth, and morphometry of the invasive marine neurotoxic dinoflagellate Alexandrium pacificum grown in metal-contaminated conditions

Author: Thierry Balliau, Cherif Chetouhi, Cecilia Teodora Satta, Estelle Masseret, Mohamed Laabir, Natacha Jean, Institut méditerranéen d'océanologie (MIO), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Toulon (UTLN)-Centre National de la Recherche Scientifique (CNRS), MARine Biodiversity Exploitation and Conservation (UMR MARBEC), Institut de Recherche pour le Développement (IRD)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Agenzia Regionale per la Ricerca in Agricoltura, Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Génétique Quantitative et Evolution - Le Moulon (Génétique Végétale) (GQE-Le Moulon), AgroParisTech-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), french research network GdR 'PHYCOTOX: Des micro-algues aux risques pour l'Homme et l'ecosysteme', Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Institut de Recherche pour le Développement (IRD), and University of Sassari
Subjects: Proteomics, Environmental Engineering, 010504 meteorology & atmospheric sciences, Proteome, Microorganism, 010501 environmental sciences, 01 natural sciences, Algal bloom, Microbiology, chemistry.chemical_compound, Tar (tobacco residue), Trace metals, Tandem Mass Spectrometry, Membrane pmteome, medicine, Environmental Chemistry, Humans, 14. Life underwater, Paralytic shellfish poisoning, Waste Management and Disposal, Ecosystem, 0105 earth and related environmental sciences, Cell Proliferation, Saxitoxin, [SDV.EE]Life Sciences [q-bio]/Ecology, environment, biology, Harmful algal bloom, Alexandrium pacificum, RuBisCO, Dinoflagellate, medicine.disease, biology.organism_classification, Pollution, chemistry, Italy, 13. Climate action, Metals, Spain, biology.protein, Dinoflagellida, Chromatography, Liquid
Abstract: International audience; Over the past decades, the occurrence, distribution and intensity of harmful algal blooms involving the dinofla-gellate Alexandrium pacificum have increased in marine coastal areas disturbed by anthropogenic inputs. This in-vasive species produces saxitoxin, which causes the paralytic shellfish poisoning syndrome in humans upon consumption of contaminated seafood. Blooms of A. pacificum have been reported in metal-contaminated coastal ecosystems, suggesting some ability of these microorganisms to adapt to and/or resist in metal stress conditions. This study seeks to characterize the modifications in membrane proteomes (by 2-D electrophoresis coupled to LC-MS/MS), cell growth and morphometry (measured with an inverted microscope), in response to metal stress (addition of Zn2+,Pb2+,Cu2+ and Cd2+), in two Mediterranean A pacOcum strains: SG C10-3 and TAR C5-4F, re-spectively isolated from the Santa Giusta Lagoon (Sardinia, Italy) and from the Tarragona seaport (Spain), both metal-contaminated ecosystems. In the SG C10-3 cultures grown in a metal cocktail, cell growth was significantly delayed, and cell size increased (22% of 37.5 mu m cells after 25 days of growth). Conversely, no substantial change was observed for cell growth or cell size in the TAR C5-4F cultures grown in a metal cocktail (P> 0.10), thus in-dicating intraspecific variability in the responses of A. pacificum strains to metal contamination. Regardless of the conditions tested, the total number of proteins constituting the membrane proteome was significantly higher for TAR C5-4F than for SG C10-3, which may help TAR C5-4F to thrive better in contaminated conditions. For both strains, the total number of proteins constituting the membrane proteomes was significantly lower in response to metal stress (29% decrease in the SG C10-3 proteome: 82 +/- 12 proteins for controls, and 58 +/- 12 in metalcontaminated cultures; 17% decrease in the TAR C5-4F proteome: 101 +/- 8 proteins for controls, and 84 +/- 5 in metal-contaminated cultures). Moreover, regardless of the strain, proteins with significantly modified expression in response to stress were mainly down-regulated (representing 45% of the proteome for SG C10-3 and 38% for TAR C5-4F), dearly showing the harmful effects of the metals. Protein down-regulation may affect cell transport (actin and phospholipid scramblase in SG C10-3), photosynthesis (RUBISCO in SG C10-3, light-harvesting protein in TAR C5-4F, and high-CO2-inducing periplasmic protein in both strains), and finally energy metabolism (ATP synthase in both strains). However, other modifications in protein expression may confer to these A. pacificum strains a capacity for adaptation and/or resistance to metal stress conditions, for example by (i) limiting the metal entry through the plasma membrane of the SG C10-3 cells (via the down-regulation of scramblase) and/or (ii) reducing the oxidative stress generated by metals in SG C10-3 and TAR C5-4F cells (due to down-regulation of ATP-synthase).
Published: 2020

33. Ensemble modelling of carbon fluxes in grasslands and croplands

Author: Elizabeth Pattey, Ute Skiba, Brian Grant, Gianni Bellocchi, Katja Klumpp, Pete Smith, Matthew T. Harrison, Val Snow, Sylvie Recous, Joanna Sharp, Fiona Ehrhardt, Arti Bhatia, Joël Léonard, Raphaël Martin, Andrew D. Moore, Jordi Doltra, Renata Sándor, Lorenzo Brilli, Jean-François Soussana, Peter Grace, Susanne Rolinski, Ward Smith, Vasileios Myrgiotis, Raia Silvia Massad, Qing Zhang, Miko U. F. Kirschbaum, Lianhai Wu, Nuala Fitton, Luca Doro, Bruno Basso, Christopher D. Dorich, Patricia Laville, Producció Vegetal, Cultius Extensius Sostenibles, Unité Mixte de Recherche sur l'Ecosystème Prairial - UMR (UREP), VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Direction scientifique Environnement, Forêt et Agriculture, Institut National de la Recherche Agronomique (INRA), Queensland University of Technology, Fractionnement des AgroRessources et Environnement (FARE), Université de Reims Champagne-Ardenne (URCA)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), University of Aberdeen, AgResearch Grasslands, Collège de Direction (CODIR), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Indian Agricultural Research Institute (IARI), Università degli Studi di Firenze = University of Florence [Firenze] (UNIFI), Catabrian Agricultural Research and Training Center (CIFA), Università degli Studi di Sassari, Agriculture and Agri-Food [Ottawa] (AAFC), British Geological Survey (BGS), Commonwealth Scientific and Industrial Research Organisation [Canberra] (CSIRO), Ecologie fonctionnelle et écotoxicologie des agroécosystèmes (ECOSYS), AgroParisTech-Université Paris-Saclay-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Transfrontalière BioEcoAgro (Transfrontalière BioEcoAgro), Université d'Artois (UA)-Université de Liège-Université de Picardie Jules Verne (UPJV)-Université du Littoral Côte d'Opale (ULCO)-Université de Lille-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Computer Laboratory [Cambridge], University of Cambridge [UK] (CAM), Scotland's Rural College (SRUC), Potsdam Institute for Climate Impact Research (PIK), Plant & Food Research, Natural Environment Research Council (NERC), Rothamsted Research, CN-MIP by Joint Programming Initiative 'FACCE' Models4Pastures by Joint Programming Initiative 'FACCE' MACSUR by Joint Programming Initiative 'FACCE' COMET-Global by Joint Programming Initiative 'FACCE' MAGGNET by Joint Programming Initiative 'FACCE' French Embassy in Budapest (Hungary) by way of 'Make Our Planet Great Again' programme Federal Ministry of Education & Research (BMBF)01LN1317AEuropean Union (EU)EC EVK2-CT2001-00105GOCE-CT-2003-505572017841SRUC, Queensland University of Technology [Brisbane] (QUT), Università degli Studi di Firenze = University of Florence (UniFI), Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Agriculture and Agri-Food (AAFC), Transfrontalière BioEcoAgro - UMR 1158 (BioEcoAgro), Université d'Artois (UA)-Université de Liège-Université de Picardie Jules Verne (UPJV)-Université du Littoral Côte d'Opale (ULCO)-Université de Lille-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-JUNIA (JUNIA), Université catholique de Lille (UCL)-Université catholique de Lille (UCL), and Biotechnology and Biological Sciences Research Council (BBSRC)
Subjects: 0106 biological sciences, [SDE.MCG]Environmental Sciences/Global Changes, Soil Science, Growing season, Atmospheric sciences, 01 natural sciences, Grassland, Temperate climate, 2. Zero hunger, Biomass (ecology), geography, geography.geographical_feature_category, Primary production, 04 agricultural and veterinary sciences, Soil carbon, 15. Life on land, Crop rotation, 13. Climate action, [SDE]Environmental Sciences, 040103 agronomy & agriculture, 0401 agriculture, forestry, and fisheries, Environmental science, Ecosystem respiration, Agronomy and Crop Science, 010606 plant biology & botany
Abstract: Croplands and grasslands are agricultural systems that contribute to land–atmosphere exchanges of carbon (C). We evaluated and compared gross primary production (GPP), ecosystem respiration (RECO), net ecosystem exchange (NEE) of CO2, and two derived outputs - C use efficiency (CUE=-NEE/GPP) and C emission intensity (IntC= -NEE/Offtake [grazed or harvested biomass]). The outputs came from 23 models (11 crop-specific, eight grassland-specific, and four models covering both systems) at three cropping sites over several rotations with spring and winter cereals, soybean and rapeseed in Canada, France and India, and two temperate permanent grasslands in France and the United Kingdom. The models were run independently over multi-year simulation periods in five stages (S), either blind with no calibration and initialization data (S1), using historical management and climate for initialization (S2), calibrated against plant data (S3), plant and soil data together (S4), or with the addition of C and N fluxes (S5). Here, we provide a framework to address methodological uncertainties and contextualize results. Most of the models overestimated or underestimated the C fluxes observed during the growing seasons (or the whole years for grasslands), with substantial differences between models. For each simulated variable, changes in the multi-model median (MMM) from S1 to S5 was used as a descriptor of the ensemble performance. Overall, the greatest improvements (MMM approaching the mean of observations) were achieved at S3 or higher calibration stages. For instance, grassland GPP MMM was equal to 1632 g C m−2 yr-1 (S5) while the observed mean was equal to 1763 m-2 yr-1 (average for two sites). Nash-Sutcliffe modelling efficiency coefficients indicated that MMM outperformed individual models in 92.3 % of cases. Our study suggests a cautious use of large-scale, multi-model ensembles to estimate C fluxes in agricultural sites if some site-specific plant and soil observations are available for model calibration. The further development of crop/grassland ensemble modelling will hinge upon the interpretation of results in light of the way models represent the processes underlying C fluxes in complex agricultural systems (grassland and crop rotations including fallow periods). info:eu-repo/semantics/acceptedVersion
Published: 2020

34. NeuPow: A CAD Methodology for High Level Power Estimation Based on Machine Learning

Author: Luigi Raffo, Jean-Christophe Prévotet, Francesca Palumbo, Carlo Sau, Tiziana Fanni, Maryline Helard, Yehya Nasser, Institut d'Électronique et des Technologies du numéRique (IETR), Université de Nantes (UN)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS), University of Cagliari, Italie, EOLAB, University of Cagliari-University of Cagliari, University of Sassari, Nantes Université (NU)-Université de Rennes 1 (UR1), Université de Nantes (UN)-Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS), Università degli Studi di Cagliari = University of Cagliari (UniCa), and Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS)
Subjects: • Power Con- sumption → Modeling, methodology Authors' addresses: Yehya NASSER, Computer science, INSA Rennes, CNRS, CAD, 02 engineering and technology, Machine learning, computer.software_genre, 01 natural sciences, Rennes, Application-specific integrated circuit, Robustness (computer science), Approximation error, • Power Estimation → CAD tools Additional Key Words and Phrases: power consumption, 0103 physical sciences, UMR 6164, 0202 electrical engineering, electronic engineering, information engineering, IETR, Univ Rennes, Electrical and Electronic Engineering, 010302 applied physics, Artificial neural network, estimation, yehyanasser@insa-rennesfr, business.industry, • Machine Learning → Artificial Neural Network, modeling, neural networks, Computer Graphics and Computer-Aided Design, 020202 computer hardware & architecture, Computer Science Applications, Power (physics), [SPI.TRON]Engineering Sciences [physics]/Electronics, CCS Concepts: • ASICs → Computer aided design, Dynamic demand, Scalability, yehyanasser@outlookcom, Artificial intelligence, France, business, computer
Abstract: International audience; In this paper, we present a new, simple, accurate and fast power estimation technique that can be used to explore the power consumption of digital system designs at an early design stage. We exploit the machine learning techniques to aid the designers in exploring the design space of possible architectural solutions, and more specifically, their dynamic power consumption, which is application, technology, frequency and data stimuli dependent. To model the power and the behavior of digital components, we adopt the Artificial Neural Networks (ANNs), while the final target technology is Application Specific Integrated Circuit (ASIC). The main characteristic of the proposed method, called NeuPow, is that it relies on propagating the signals throughout connected ANN models to predict the power consumption of a composite system. Besides a baseline version of the NeuPow methodology that works for a given predefined operating frequency, we also derive an upgraded version that is frequency aware, where the same operating frequency is taken as additional input by the ANN models. To prove the effectiveness of the proposed methodology, we perform different assessments at different levels. Moreover, technology and scalability studies have been conducted, proving the NeuPow robustness in terms of these design parameters. Results show a very good estimation accuracy with less than 9% of relative error independently from the technology and the size/layers of the design. NeuPow is also delivering a speed-up factor of about 84× with respect to the classical power estimation flow.
Published: 2020

35. Ecosystems

Author: Balzan, Mario V, Hassoun, Abed El Rahman, Aroua, Najet, Baldy, Virginie, Dagher, Magda Bou, Branquinho, Cristina, Dutay, Jean-Claude, El Bour, Monia, Médail, Frédéric, Mojtahid, Meryem, Morán-Ordóñez, Alejandra, Roggero, Pier Paolo, Heras, Sergio Rossi, Schatz, Bertrand, Vogiatzakis, Ioannis N., Zaimes, George N., Ziveri, Patrizia, Malta Council for Science and Technology, National Council for Scientific Research = Conseil national de la recherche scientifique du Liban [Lebanon] (CNRS-L), Université Mohamed Khider de Biskra (BISKRA), Institut méditerranéen de biodiversité et d'écologie marine et continentale (IMBE), Avignon Université (AU)-Aix Marseille Université (AMU)-Institut de recherche pour le développement [IRD] : UMR237-Centre National de la Recherche Scientifique (CNRS), Université Saint-Joseph de Beyrouth (USJ), Centre for Ecology, Evolution and Environmental Changes, Faculty of Sciences, University of Lisbon, Lisbon, Portugal, Laboratoire des Sciences du Climat et de l'Environnement [Gif-sur-Yvette] (LSCE), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Modélisation du climat (CLIM), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Institut National des Sciences et Technologies de la Mer [Salammbô] (INSTM), Centre de Ciència i Tecnologia Forestal de Catalunya (CTFC), Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Department of Biological and Environmental Sciences (DiSTeBA), Uniersity of Salento, Salento, Italy, Open University of Cyprus, Nicosia, Cyprus, UNESCO Chair Con-E-Ect, International Hellenic University, Drama, Greece, Universitat Autònoma de Barcelona (UAB), Cramer W, Guiot J, and Marini K
Subjects: [SDE]Environmental Sciences, ComputingMilieux_MISCELLANEOUS
Abstract: International audience
Published: 2020

36. Organization of intensive cardiac care units in Europe: Results of a multinational survey

Author: C Hassenger, Michael Koutouzis, M Sivagowry Rasalingam, Marek Gierlotka, J Belohlavev, Christophe Beauloye, Nikolaos Nikolaou, Gianni Casella, N Radovanovic, Zaza Iakobishvili, Marija Vavlukis, Eric Bonnefoy, E Trendafilova, M Lettino, Holger Thiele, Diana Tint, L. de Luca, K Daly, François Roubille, I Zakke, S Monteiro, Pranas Šerpytis, R Zukermann, Ahmed Magdy, Toomas Marandi, C Held, Zdravko Babić, Marc J. Claeys, D Arroyo, Alessandro Sionis, Susanna Price, Department of Cardiology, Antwerp University Hospital, Belgium. 2, Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Physiologie & médecine expérimentale du Cœur et des Muscles [U 1046] (PhyMedExp), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Department of Cardiology, Ospedale Maggiore, Italy, Rambam Medical Health Center, Israel., National Center for Scientific Research 'Demokritos' (NCSR), Università degli Studi di Sassari [Sassari] (UNISS), Department of Cardiology, University of Opole, Poland., Heart Institute, Holon Medical Center, Israel., Heart Center Leipzig, University Hospital, Germany, Red Cross General Hospital, Greece, Hospital de la Santa Creu i Sant Pau, Coimbra University Hospital, Portugal, Cliniques Universitaires Saint Luc, UCLouvain, Belgium., Department of Medical Sciences, Uppsala Clinical Research Center, Sweden, ICCO Clinics, Transilvania University, Romania., Pauls Stradins Clinical University Hospital, Latvia, Faculty of Medicine, Vilnius University, Lithuania, University Hospital Centre, Sisters of Mercy, Croatia, 2nd Department of Medicine, Charles University, Czech Republic., National Heart Institution, Egypt., Department of Cardiology, Aarhus University Hospital, Denmark., Teagasc - The Agriculture and Food Development Authority (Teagasc), University College Hospital, Ireland, Hôpital Cantonal Fribourg, Switzerland., PHO University Clinic of Cardiology, Macedonia., Clinical Center of Serbia, Emergency Center, Serbia., ICCU, National Cardiology Hospital, Bulgaria, North Estonia Medical Centre, Department of Cardiology, University of Tartu, Estonia, Department of Cardiology, Rigshospitalet, Denmark, Department of Clinical Medicine, University of Copenhagen, Denmark, Division of Cardiology, San Gerardo Hospital, Italy, Adult Intensive Care Unit, Royal Brompton Hospital, London., Evaluation et modélisation des effets thérapeutiques, Département biostatistiques et modélisation pour la santé et l'environnement [LBBE], Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS), Intensive Cardiac Care Unit, Hospices Civils de Lyon, France., Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Charles University [Prague] (CU), University of Tartu, University of Copenhagen = Københavns Universitet (UCPH), and MORNET, Dominique
Subjects: Heart Diseases, [SDV]Life Sciences [q-bio], education, 030204 cardiovascular system & hematology, Critical Care and Intensive Care Medicine, Unit (housing), 03 medical and health sciences, 0302 clinical medicine, Patient Admission, Risk Factors, acute cardiovascular care, Surveys and Questionnaires, Severity of illness, Medicine, Humans, 030212 general & internal medicine, health care economics and organizations, business.industry, Intensive cardiac care unit, General Medicine, organization, medicine.disease, TRENDS, EVOLUTION, Europe, [SDV] Life Sciences [q-bio], Intensive Care Units, Cardiac Care Facilities, Multinational corporation, PATTERNS, Medical emergency, Human medicine, admission policy, Morbidity, Cardiology and Cardiovascular Medicine, business
Abstract: Background: The present survey aims to describe the intensive cardiac care unit organization and admission policies in Europe. Methods: A total of 228 hospitals (61% academic) from 27 countries participated in this survey. In addition to the organizational aspects of the intensive cardiac care units, including classification of the intensive cardiac care unit levels, data on the admission diagnoses were gathered from consecutive patients who were admitted during a two-day period. Admission policies were evaluated by comparing illness severity with the intensive cardiac care unit level. Gross national income was used to differentiate high-income countries (n=13) from middle-income countries (n=14). Results: A total of 98% of the hospitals had an intensive cardiac care unit: 70% had a level 1 intensive cardiac care unit, 76% had a level 2 intensive cardiac care unit, 51% had a level 3 intensive cardiac care unit, and 60% of the hospitals had more than one intensive cardiac care unit level. High-income countries tended to have more level 3 intensive cardiac care units than middle-income countries (55% versus 41%, p=0.07). A total of 5159 admissions were scored on illness severity: 63% were low severity, 24% were intermediate severity, and 12% were high severity. Patients with low illness severity were predominantly admitted to level 1 intensive cardiac care units, whereas patients with high illness severity were predominantly admitted to level 2 and 3 intensive cardiac care units. A policy mismatch was observed in 12% of the patients; some patients with high illness severity were admitted to level 1 intensive cardiac care units, which occurred more often in middle-income countries, whereas some patients with low illness severity were admitted to level 3 intensive cardiac care units, which occurred more frequently in high-income countries. Conclusion: More than one-third of the admitted patients were considered intermediate or high risk. Although patients with higher illness severity were mostly admitted to high-level intensive cardiac care units, an admission policy mismatch was observed in 12% of the patients; this mismatch was partly related to insufficient logistic intensive cardiac care unit capacity.
Published: 2020

37. TRY plant trait database – enhanced coverage and open access

Author: Kattge, J., Bonisch, G., Diaz, S., Lavorel, S., Prentice, I. C., Leadley, P., Tautenhahn, S., Werner, G. D. A., Aakala, T., Abedi, M., Acosta, A. T. R., Adamidis, G. C., Adamson, K., Aiba, M., Albert, C. H., Alcantara, J. M., Alcazar, C C., Aleixo, I., Ali, H., Amiaud, B., Ammer, C., Amoroso, M. M., Anand, M., Anderson, C., Anten, N., Antos, J., Apgaua, D. M. G., Ashman, T. L., Asmara, D. H., Asner, G. P., Aspinwall, M., Atkin, O., Aubin, I., Baastrup-Spohr, L., Bahalkeh, K., Bahn, M., Baker, T., Baker, W. J., Bakker, J. P., Baldocchi, D., Baltzer, J., Banerjee, A., Baranger, A., Barlow, J., Barneche, D. R., Baruch, Z., Bastianelli, D., Battles, J., Bauerle, W., Bauters, M., Bazzato, E., Beckmann, M., Beeckman, H., Beierkuhnlein, C., Bekker, R., Belfry, G., Belluau, M., Beloiu, M., Benavides, R., Benomar, L., Berdugo-Lattke, M. L., Berenguer, E., Bergamin, R., Bergmann, J., Bergmann Carlucci, M., Berner, L., Bernhardt Romermann, M., Bigler, C., Bjorkman, A. D., Blackman, C., Blanco, C., Blonder, B., Blumenthal, D., Bocanegra Gonzalez, K. T., Boeckx, P., Bohlman, S., Bohning Gaese, K., Boisvert Marsh, L., Bond, W., Bond-Lamberty, B., Boom, A., Boonman, C. C. F., Bordin, K., Boughton, E. H., Boukili, V., Bowman, D. M. J. S., Bravo, S., Brende, l M. R., Broadley, M. R., Brown, K. A., Bruelheide, H., Brumnich, F., Bruun, H. H., Bruy, D., Buchanan, S. W., Bucher, S. F., Buchmann, N., Buitenwerf, R., Bunker, D. E., Burge, r J., Burrascano, S., Burslem, D. F. R. P., Butterfield, B. J., Byun, C., Marques, M., Scalon, M. C., Caccianiga, M., Cadotte, M., Cailleret, M., Camac, J., Camarero, J. J., Campany, C., Campetella, G., Campos, J. A., Cano Arboleda, L., Canullo, R., Carbognani, M., Carvalho, F., Casanoves, F., Castagneyrol, B., Catford, J. A., Cavender Bares, J., Cerabolini, B. E. L., Cervellini, M., Chacon Madrigal, E., Chapin, K., Chapin, F. S., Chelli, S., Chen, S. C., Chen, A., Cherubini, P., Chianucci, F., Choat, B., Chung, K. S., Chytry, M., Ciccarelli, D., Coll, L., Collins, C. G., Conti, L., Coomes, D., Cornelissen, J. H. C., Cornwell, W. K., Corona, P., Coyea, M., Craine, J., Craven, D., Cromsigt, J. P. G. M., Csecserits, A., Cufar, K., Cuntz, M., da Silva, A. C., Dahlin, K. M., Dainese, M., Dalke, I., Dalle Fratte, M., Dang Le, A. T., Danihelka, J., Dannoura, M., Dawson, S., de Beer, A. J., De Frutos, A., De Long, J. R., Dechant, B., Delagrange, S., Delpierre, N., Derroire, G., Dias, A. S., Diaz Toribio, M. H., Dimitrakopoulos, P. G., Dobrowolski, M., Doktor, D., Drevojan, P., Dong, N., Dransfield, J., Dressler, S., Duarte, L., Ducouret, E., Dullinger, S., Durka, W., Duursma, R., Dymova, O., E- Vojtko, A., Eckstein, R. L., Ejtehadi, H., Elser, J., Emilio, T., Engemann, K., Erfanian, M. B., Erfmeier, A., Esquivel Muelbert, A., Esser, G., Estiarte, M., Domingues, T. F., Fagan, W. F., Fagundez, J., Falster, D. S., Fan, Y., Fang, J., Farris, E., Fazlioglu, F., Feng, Y., Fernandez, Mendez, Ferrara, C., Ferreira, J., Fidelis, A., Finegan, B., Firn, J., Flowers, T. J., Flynn, D. F. B., Fontana, V., Forey, E., Forgiarini, C., Francois, L., Frangipani, M., Frank, D., Frenette Dussault, C., Freschet, G. T., Fry, E. L., Fyllas, N. M., Mazzochini, G. G., Gachet, S., Gallagher, R., Ganade, G., Ganga, F., Garcia Palacios, P., Gargaglione, V., Garnier, E., Garrido, J. L., de Gasper, A. L., Gea Izquierdo, G., Gibson, D., Gillison, A. N., Giroldo, A., Glasenhardt, M. C., Gleason, S., Gliesch, M., Goldberg, E., Goldel, B., Gonzalez Akre, E., Gonzalez Andujar, J. L., Gonzalez Melo, A., Gonzalez Robles, A., Graae, B. J., Granda, E., Graves, S., Green, W. A., Gregor, T., Gross, N., Guerin, G. R., Gunther, A., Gutierrez, A. G., Haddock, L., Haines, A., Hall, J., Hambuckers, A., Han, W., Harrison, S. P., Hattingh, W., Hawes, J. E., He, T., He, P., Heberling, J. M., Helm, A., Hempel, S., Hentschel, J., Herault, B., Heres, A. M., Herz, K., Heuertz, M., Hickler, T., Hietz, P., Higuchi, P., Hipp, A. L., Hirons, A., Hock, M., Hogan, J. A., Holl, K., Honnay, O., Hornstein, D., Hou, E., Hough Snee, N., Hovstad, K. A., Ichie, T., Igic, B., Illa, E., Isaac, M., Ishihara, M., Ivanov, L., Ivanova, L., Iversen, C. M., Izquierdo, J., Jackson, R. B., Jackson, B., Jactel, H., Jagodzinsk, A. M., Jandt, U., Jansen, S., Jenkins, T., Jentsch, A., Jespersen, J. R. P., Jiang, G. F., Johansen, J. L., Johnson, D., Jokela, E. J., Joly, C. A., Jordan, G. J., Joseph, G. S., Junaedi, D., Junker, R. R., Justes, E., Kabzems, R., Kane, J., Kaplan, Z., Kattenborn, T., Kavelenova, L., Kearsley, E., Kempel, A., Kenzo, T., Kerkhoff, A., Khalil, M. I., Kinlock, N. L., Kissling, W. D., Kitajima, K., Kitzberger, T., Kjoller, R., Klein, T., Kleyer, M., Klimesova, J., Klipel, J., Kloeppel, B., Klotz, S., Knops, J. M. H., Kohyama, T., Koike, F., Kollmann, J., Komac, B., Komatsu, K., Konig, C., Kraft, N. J. B., Kramer, K., Kreft, H., Kuhn, I., Kumarathune, D., Kuppler, J., Kurokawa, H., Kurosawa, Y., Kuyah, S., Laclau, J. P., Lafleur, B., Lallai, E., Lamb, E., Lamprecht, A., Larkin, D. J., Laughlin, D., Le Bagousse Pinguet, Y., le Maire, G., le Roux, P. C., le Roux, E., Lee, T., Lens, F., Lewis, S. L., Lhotsky, B., Li, Y., Li, X., Lichstein, J. W., Liebergesell, M., Lim, J. Y., Lin, Y. S., Linares, Y. C., Liu, C., Liu, D., Liu, U., Livingstone, S., Llusia, J., Lohbeck, M., Lopez Garcia, A., Lopez Gonzalez, G., Lososov, a Z., Louault, F., Lukacs, B. A., Lukes, P., Luo, Y., Lussu, M., Ma, S., Maciel Rabelo Pereira, C., Mack, M., Maire, V., Makela, A., Makinen, H., Malhado, A. C. M., Mallik, A., Manning, P., Manzoni, S., Marchetti, Z., Marchino, L., Marcilio Silva, V., Marcon, E., Marignani, M., Markesteijn, L., Martin, A., Martinez Garza, C., Martinez Vilalta, J., Maskova, T., Mason, K., Mason, N., Massad, T. J., Masse, J., Mayrose, I., Mccarthy, J., Mccormack, M. L., Mcculloh, K., Mcfadden, I., Mcgill, B. J., Mcpartland, M. Y., Medeiros, J., Medlyn, B., Meerts, P., Mehrabi, Z., Meir, P., Melo, F., P. L., Mencuccini, M., Meredieu, C., Messier, J., Meszaros, I., Metsaranta, J., Michaletz, S. T., Michelaki, C., Migalina, S., Milla, R., Miller, J., E. D., Minden, V., Ming, R., Mokany, K., Moles, A. T., Molnar, A., Molofsky, J., Molz, M., Montgomery, R. A., Monty, A., Moravcova, L., Moreno Martinez, A., Moretti, M., Mori, A. S., Mori, S., Morris, D., Morrison, J., Mucina, L., Mueller, S., Muir, C. D., Muller, S. C., Munoz, F., Myers Smith, I. H., Myster, R. W., Nagano, M., Naidu, S., Narayanan, A., Natesan, B., Negoita, L., Nelson, A. S., Neuschulz, E. L., Ni, J., Niedrist, G., Nieto, J., Niinemets, U., Nolan, R., Nottebrock, H., Nouvellon, Y., Novakovskiy, A., Nystuen, K. O., O'Grady, A., O'Hara, K., O'Reilly Nugent, A., Oakley, S., Oberhuber, W., Ohtsuka, T., Oliveira, R., Ollerer, K., Olson, M. E., Onipchenko, V., Onoda, Y., Onstein, R. E., Ordonez, J. C., Osada, N., Ostonen, I., Ottaviani, G., Otto, S., Overbeck, G. E., Ozinga, W. A., Pahl, A. T., Paine, C. E. T., Pakeman, R. J., Papageorgiou, A. C., Parfionova, E., Partel, M., Patacca, M., Paula, S., Paule, J., Pauli, H., Pausas, J., Peco, B., Penuelas, J., Perea, A., Peri, P. L., Petisco Souza, A. C., Petraglia, A., Petritan, A. M., Phillips, O. L., Pierce, S., Pillar, V. D., Pisek, J., Pomogaybin, A., Poorter, H., Portsmuth, A., Poschlod, P., Potvin, C., Pounds, D., Powell, A., Power, S. A., Prinzing, A., Puglielli, G., Pysek, P., Raevel, V., Rammig, A., Ransijn, J., Ray, C. A., Reich, P. B., Reichstein, M., Reid, D. E. B., Rejou Mechain, M., de Dios, V. R., Ribeiro, S., Richardson, S., Riibak, K., Rillig, M. C., Riviera, F., Robert, E. M. R., Roberts, S., Robroek, B., Roddy, A., Rodrigues, A. V., Rogers, A., Rollinson, E., Rolo, V., Romermann, C., Ronzhina, D., Roscher, C., Rosell, J. A., Rosenfield, M. F., Rossi, C., Roy, D. B., Royer Tardif, S., Ruger, N., Ruiz Peinado, R., Rumpf, S. B., Rusch, G. M., Ryo, M., Sack, L., Saldana, A., Salgado Negret, B., Salguero Gomez, R., Santa Regina, I., Santacruz Garcia, A. C., Santos, J., Sardans, J., Schamp, B., Scherer Lorenzen, M., Schleuning, M., Schmid, B., Schmidt, M., Schmitt, S., Schneider, J. V., Schowanek, S. D., Schrader, J., Schrodt, F., Schuldt, B., Schurr, F., Selaya Garvizu, G., Semchenko, M., Seymour, C., Sfair, J. C., Sharpe, J. M., Sheppard, C. S., Sheremetiev, S., Shiodera, S., Shipley, B., Shovon, T. A., Siebenkas, A., Sierra, C., Silva, V., Silva, M., Sitzia, T., Sjoman, H., Slot, M., Smith, N. G., Sodhi, D., Soltis, P., Soltis, D., Somers, B., Sonnier, G., Sorensen, M. V., Sosinski, E. E., Soudzilovskaia, N. A., Souza, A. F., Spasojevic, M., Sperandii, M. G., Stan, A. B., Stegen, J., Steinbauer, K., Stephan, J. G., Sterck, F., Stojanovic, D. B., Strydom, T., Suarez, M. L., Svenning, J. C., Svitkova, I., Svitok, M., Svoboda, M., Swaine, E., Swenson, N., Tabarelli, M., Takagi, K., Tappeiner, U., Tarifa, R., Tauugourdeau, S., Tavsanoglu, C., te Beest, M., Tedersoo, L., Thiffault, N., Thom, D., Thomas, E., Thompson, K., Thornton, P. E., Thuiller, W., Tichy, L., Tissue, D., Tjoelker, M. G., Tng, D. Y. P., Tobias, J., Torok, P., Tarin, T., Torres Ruiz, J. M., Tothmeresz, B., Treurnicht, M., Trivellone, V., Trolliet, F., Trotsiuk, V., Tsakalos, J. L., Tsiripidis, I., Tysklind, N., Umehara, T., Usoltsev, V., Vadeboncoeur, M., Vaezi, J., Valladares, F., Vamosi, J., van Bodegom, P. M., van Breugel, M., Van Cleemput, E., van de Weg, M., van der Merwe, S., van der Plas, F., van der Sande, M. T., van Kleunen, M., Van Meerbeek, K., Vanderwel, M., Vanselow, K. 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C., Zotz, G., Wirth, C., Systèmes d'élevage méditerranéens et tropicaux (UMR SELMET), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut National de la Recherche Agronomique (INRA)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Laboratoire de Physique et Physiologie Intégratives de l’Arbre en environnement Fluctuant - Clermont Auvergne (PIAF), Université Clermont Auvergne (UCA)-Institut National de la Recherche Agronomique (INRA), Botanique et Modélisation de l'Architecture des Plantes et des Végétations (UMR AMAP), Institut de Recherche pour le Développement (IRD [France-Sud])-Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut National de la Recherche Agronomique (INRA)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Biodiversité, Gènes & Communautés (BioGeCo), Institut National de la Recherche Agronomique (INRA)-Université de Bordeaux (UB), SILVA (SILVA), AgroParisTech-Université de Lorraine (UL)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Ecologie des forêts de Guyane (UMR ECOFOG), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut National de la Recherche Agronomique (INRA)-AgroParisTech-Université de Guyane (UG)-Centre National de la Recherche Scientifique (CNRS)-Université des Antilles (UA), Unité Mixte de Recherche sur l'Ecosystème Prairial - UMR (UREP), Institut National de la Recherche Agronomique (INRA)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS), Ecologie fonctionnelle et biogéochimie des sols et des agro-écosystèmes (UMR Eco&Sols), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut de Recherche pour le Développement (IRD)-Institut National de la Recherche Agronomique (INRA)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Unité Expérimentale Forêt Pierroton (UEFP), Institut National de la Recherche Agronomique (INRA), Max Planck Institute for Biogeochemistry Max Planck SocietyFoundation CELLEX German Centre for Integrative Biodiversity Research (iDiv) Halle-Jena-Leipzig International Programme of Biodiversity Science (DIVERSITAS) International Geosphere-Biosphere Programme (IGBP) French Foundation for Biodiversity Research (FRB) GIS 'Climat, Environnement et Societe' France AXA Research Fund NERC Natural Environment Research Council Future Earth, Max Planck Institute for Biogeochemistry (MPI-BGC), Max-Planck-Gesellschaft, German Centre for Integrative Biodiversity Research (iDiv), Instituto Multidisciplinario de Biología Vegetal [Córdoba] (IMBIV), Consejo Nacional de Investigaciones Científicas y Técnicas [Buenos Aires] (CONICET)-Facultad de Ciencias Exactas, Físicas y Naturales [Córdoba], Universidad Nacional de Córdoba [Argentina]-Universidad Nacional de Córdoba [Argentina], Laboratoire d'Ecologie Alpine (LECA ), Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), Imperial College London, Ecologie Systématique et Evolution (ESE), AgroParisTech-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Department of Zoology [Oxford], University of Oxford, Balliol College, Helsingin yliopisto = Helsingfors universitet = University of Helsinki, Tarbiat Modares University [Tehran], Università degli Studi Roma Tre = Roma Tre University (ROMA TRE), Department of Environment [Aegean], University of the Aegean, Institute of Ecology and Evolution [Bern, Switzerland], University of Bern, University of Tartu, Tohoku University [Sendai], Institut méditerranéen de biodiversité et d'écologie marine et continentale (IMBE), Avignon Université (AU)-Aix Marseille Université (AMU)-Institut de recherche pour le développement [IRD] : UMR237-Centre National de la Recherche Scientifique (CNRS), Universidad de Jaén (UJA), Instituto Alexander Von Humboldt, Bogota, Colombia, National Institute of Amazonian Research (INPA), Manaus, Brazil, Botany Department, Faculty of Science, Suez Canal University, Ismailia, Egypt, Laboratoire Agronomie et Environnement - Antenne Colmar (LAE-Colmar ), Laboratoire Agronomie et Environnement (LAE), Université de Lorraine (UL)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université de Lorraine (UL)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Forest Sciences, University of Göttingen, Göttingen, Germany, Centre for Biodiversity and Sustainable Land-use [University of Göttingen] (CBL), Georg-August-University = Georg-August-Universität Göttingen, Instituto de Investigaciones en Recursos Naturales, Agroecología y Desarrollo Rural (IRNAD), Universidad Nacional de Río Negro, El Bolsón, Argentina, Consejo Nacional de Investigaciones Científicas y Técnicas [Buenos Aires] (CONICET), School of Environmental Sciences, University of Guelph, Pacific Northwest National Laboratory, Richland, WA, USA, University of Massachusetts [Amherst] (UMass Amherst), University of Massachusetts System (UMASS), Centre for Crop Systems Analysis, Wageningen University and Research [Wageningen] (WUR), University of Victoria [Canada] (UVIC), College of Science & Engineering, James Cook University, Smithfield, Qld, Australia, University of Pittsburgh, Pittsburgh, PA, USA, Centre for Forest Research, Institute for Integrative Systems Biology, Université Laval, Quebec, QC, Canada, Arizona State University, Tempe, AZ, USA, University of North Florida [Jacksonville] (UNF), Australian National University (ANU), Great Lakes Forestry Centre, Canadian Forest Service, Natural Resources Canada, Sault Ste. Marie, ON, Canada, Department of Biology [Copenhagen], Faculty of Science [Copenhagen], University of Copenhagen = Københavns Universitet (UCPH)-University of Copenhagen = Københavns Universitet (UCPH), Department of Ecology [Innsbruck], Leopold Franzens Universität Innsbruck - University of Innsbruck, University of Leeds, Royal Botanic Gardens Kew, Richmond, UK, Conservation Ecology, Groningen Institute for Evolutionary Life Sciences (GELIFES), University of Groningen, Groningen, The Netherlands, Lawrence Berkeley National Laboratory [Berkeley] (LBNL), Biology Department, Wilfrid Laurier University, Waterloo, ON, Canada, Department of Forest Resources, University of Minnesota, St. Paul, MN, USA, AgroParisTech, Lancaster Environment Centre, Lancaster University, University of Exeter, University of Adelaide, Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro - Montpellier SupAgro, Département Environnements et Sociétés (Cirad-ES), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad), University of California [Berkeley] (UC Berkeley), University of California (UC), Department of Horticulture and Landscape Architecture, Colorado State University, Fort Collins, CO, USA, Universiteit Gent = Ghent University (UGENT), Università degli Studi di Cagliari = University of Cagliari (UniCa), Helmholtz Zentrum für Umweltforschung = Helmholtz Centre for Environmental Research (UFZ), Royal Museum for Central Africa, Tervuren, Belgium, Bayreuth Center of Ecology and Environmental Research (BayCEER), Groningen Institute of Archaeology (GIA), University of Groningen, Groningen, The Netherlands, Department of Biological Sciences, University of Tennessee, Knoxville, TN, USA, Rocky Mountain Biological Laboratory, Crested Butte, CO, USA, Département des Science, Université du Québec À Montréal, Montreal, QC, Canada, Department of Biogeography, University of Bayreuth, Bayreuth, Germany, Museo Nacional de Ciencias Naturales [Madrid] (MNCN), Consejo Superior de Investigaciones Científicas [Madrid] (CSIC), Université Laval, Quebec, QC, Canada, Instituto de Ciencias Naturales, Universidad Nacional de Colombia, Bogota, Colombia, Fundación Natura, Bogota, Colombia, Environmental Change Institute, Laboratório de Estudos em Vegetação Campestre (LEVCamp), Programa de Pós-Graduação em Botânica, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil, Freie Universität Berlin, Berlin-Brandenburg Institute of Advanced Biodiversity Research (BBIB), Berlin, Germany, Laboratório de Ecologia Funcional de Comunidades (LABEF), Departamento de Botânica, Universidade Federal do Paraná, Curitiba, Brazil, School of Informatics, Computing, and Cyber Systems (SICCS), Northern Arizona University [Flagstaff], Institute of Ecology and Evolution, Friedrich Schiller University Jena, Jena, Germany, ETH Zurich, Universitatstrasse 16, 8092 Zurich, Switzerland, University of Gothenburg (GU), Laboratoire de Physique et Physiologie Intégratives de l’Arbre en environnement Fluctuant (PIAF), Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Universidade Federal do Rio Grande do Sul [Porto Alegre] (UFRGS), School of Life Sciences, Arizona State University, Tempe, AZ, USA, USDA-ARS Rangeland Resources & Systems Research Unit, Fort Collins, CO, USA, Grupo de Investigación en Biodiversidad y Dinámica de Ecosistémas Tropicales - Universidad del Tolima, Ibagué, Colombia, Laboratory of Applied Physical Chemistry - ISOFYS (Gent, Belgium), School of Forest Resources and Conservation [Gainesville] (UF|IFAS|FFGS), Institute of Food and Agricultural Sciences [Gainesville] (UF|IFAS), University of Florida [Gainesville] (UF)-University of Florida [Gainesville] (UF), Senckenberg Biodiversity and Climate Research Centre, Frankfurt am Main, Germany, Department of Biological Sciences, Goethe Universität Frankfurt, Frankfurt am Main, Germany, Department of Biological Sciences, University of Cape Town, Cape Town, South Africa, SAEON Fynbos Node, Claremont, South Africa, Pacific Northwest National Laboratory, College Park, MD, USA, University of Leicester, Department of Environmental Science, Institute for Water and Wetland Research, Radboud University, Nijmegen, The Netherlands, Laboratório de Ecologia Vegetal (LEVEG), Programa de Pós-Graduação em Ecologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil, Archbold Biological Station’s Buck Island Ranch, FL, Lake Placid, USA, Department of Ecology and Evolutionary Biology, University of Connecticut, Storrs, CT, USA, University of Tasmania [Hobart, Australia] (UTAS), Facultad de Ciencias Forestales, Universidad Nacional de Santiago del Estero, Santiago del Estero, Argentina, Universität Hohenheim, School of Geography, University of Nottingham, Nottingham, UK, Department of Geography and Geology, Kingston University, Kingston upon Thames, UK, Martin-Luther-Universität Halle Wittenberg (MLU), Facultad de Ingeniería y Ciencias Hídricas, Universidad Nacional del Litoral (FICH-UNL), Santa Fe, Argentina, Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institut de Recherche pour le Développement (IRD [Nouvelle-Calédonie]), University of Toronto at Scarborough, Friedrich-Schiller-Universität = Friedrich Schiller University Jena [Jena, Germany], Section for Ecoinformatics and Biodiversity, Department of Bioscience, Aarhus University, Aarhus, Denmark, Center for Biodiversity Dynamics in a Changing World (BIOCHANGE), Department of Bioscience, Aarhus University, Aarhus, Denmark, New Jersey Institute of Technology [Newark] (NJIT), University of Rostock, Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome] (UNIROMA), School of Biological Sciences, University of Aberdeen, Aberdeen, UK, Center for Ecosystem Science and Society, Northern Arizona University, Flagstaff, AZ, USA, School of Civil and Environmental Engineering, Yonsei University, Seoul, Korea, Departamento de Botânica, SCB, UFPR – Federal University of Parana, Curitiba, Brazil, Centro Politécnico, Universidade Federal do Paraná, Curitiba, Brazil, Università degli Studi di Milano = University of Milan (UNIMI), Risques, Ecosystèmes, Vulnérabilité, Environnement, Résilience (RECOVER), Aix Marseille Université (AMU)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Department of Environmental Systems Science, ETH Zürich, Zürich, Switzerland, Swiss Federal Institute for Forest, Snow and Landscape Research WSL, Centre of Excellence for Bioscurity Risk Analysis, The University of Melbourne, Melbourne, Vic., Australia, Centro de Investigaciones Biológicas (CSIC), Colgate University, Hamilton, NY, USA, School of Biosciences and Veterinary Medicine, Plant Diversity and Ecosystems Management Unit, University of Camerino, Camerino, Italy, University of the Basque Country/Euskal Herriko Unibertsitatea (UPV/EHU), Departamento de Geociencias y Medio Ambiente, Universidad Nacional de Colombia, Medellin, Colombia, Università degli studi di Parma = University of Parma (UNIPR), Centro Agronómico Tropical de Investigación y Enseñanza - Tropical Agricultural Research and Higher Education Center (CATIE), Université de Bordeaux (UB)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Department of Geography, King’s College London, London, UK, University of Minnesota [Twin Cities] (UMN), University of Minnesota System, Universitá degli Studi dell’Insubria = University of Insubria [Varese] (Uninsubria), Alma Mater Studiorum Università di Bologna [Bologna] (UNIBO), Universidad de Costa Rica (UCR), University of Arizona, Institute of Arctic Biology, University of Alaska [Fairbanks] (UAF), Royal Botanic Gardens [Kew], Department of Biology [Fort Collins], Colorado State University [Fort Collins] (CSU), WSL Swiss Federal Research Institute, Birmensdorf, Switzerland, Faculty of Forestry, University of British Columbia, Vancouver, BC, Canada, CREA – Research Centre for Forestry and Wood, Arezzo, Italy, Western Sydney University, ungwon University, Goesan, Chungbuk, Korea, Department of Botany and Zoology [Brno] (SCI / MUNI), Faculty of Science [Brno] (SCI / MUNI), Masaryk University [Brno] (MUNI)-Masaryk University [Brno] (MUNI), University of Pisa - Università di Pisa, Department of Agriculture and Forest Engineering (EAGROF), University of Lleida, Lleida, Spain, Joint Research Unit CTFC – AGROTECNIO, Solsona, Spain, University of California Riverside, Riverside, CA, USA, Faculty of Environmental Sciences, University of Life Sciences Prague, Institute of Botany of the Czech Academy of Sciences (IB / CAS), Czech Academy of Sciences [Prague] (CAS), University of Cambridge [UK] (CAM), Systems Ecology, Department of Ecological Science, Vrije Universiteit, Amsterdam, The Netherlands, School of Biological, Earth and Environmental Sciences, UNSW Sydney, Sydney, NSW, Australia, Faculté de foresterie, de géographie et de géomatique, Université Laval, Quebec, QC, Canada, Jonah Ventures, Boulder, CO, USA, Centro de Modelación y Monitoreo de Ecosistemas, Universidad Mayor, Santiago, Chile, Department of Wildlife, Fish and Environmental Studies, Swedish University of Agricultural Sciences (SLU), Centre for African Conservation Ecology, Department of Zoology, Nelson Mandela University, Port Elizabeth, South Africa, MTA Centre for Ecological Research [Tihany], Hungarian Academy of Sciences (MTA), University of Ljubljana, Santa Catarina State University, Lages, SC, Brazil, Department of Geography, Environment, and Spatial Sciences, Michigan State University, East Lansing, MI, USA, Eurac Research, Institute for Alpine Environment, Bozen-Bolzano, Italy, Institute of Biology of Komi Science Centre of the Ural Branch of the Russian Academy of Sciences, Syktyvkar, Komi Republic, Russia, University of Science – Vietnam National University Ho Chi Minh City, Ho Chi Minh City, Vietnam, Graduate School of Agriculture, Kyoto University, Kyoto, Japan, Graduate School of Global Environmental Studies, Kyoto University, Kyoto, Japan, Swedish Species Information Centre, University of Pretoria [South Africa], Helmholtz Centre for Environmental Research – UFZ, Leipzig, Germany, Department of Terrestrial Ecology, Netherlands Institute of Ecology, Wageningen, The Netherlands, Department Computational Landscape Ecology [UFZ Leipsig], Department Computational Hydrosystems, UFZ – Helmholtz Centre for Environmental Research, Leipzig, Germany, Seoul National University [Seoul] (SNU), Institute of Temperate Forest Sciences (ISFORT), Ripon, QC, Canada, UQO, Department of Natural Sciences, Ripon, QC, Canada, Université Paris-Sud - Paris 11 (UP11)-AgroParisTech-Centre National de la Recherche Scientifique (CNRS), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-AgroParisTech-Université de Guyane (UG)-Centre National de la Recherche Scientifique (CNRS)-Université des Antilles (UA)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Goethe-Universität Frankfurt am Main, University of Florida [Gainesville] (UF), The University of Western Australia (UWA), School of Biological Sciences, The University of Western Australia, Department of Biological Sciences, Macquarie University, Department of Botany and Molecular Evolution, Senckenberg Research Institute and Natural History Museum, Universität Wien, Karlstad University [Sweden], Ferdowsi University of Mashhad (FUM), Flathead Lake Biological Station, University of Montana, School of Sustainability, Arizona State University, Programa Nacional de Pós-Doutorado (PNPD), Programa de Pós Graduação em Ecologia, Institute of Biology, University of Campinas UNICAMP, Institute for Ecosystem Research/Geobotany, Kiel University, School of Geography, Earth and Environmental Sciences [Birmingham], University of Birmingham [Birmingham], Justus-Liebig-Universität Gießen = Justus Liebig University (JLU), Global Ecology Unit CREAF-CEAB-CSIC, Universitat Autònoma de Barcelona (UAB), FFCLRP-USP, Department of Biology [USA], University of Maryland [College Park], University of Maryland System-University of Maryland System, University of A Coruña (UDC), School of Physics [UNSW Sydney] (UNSW), University of New South Wales [Sydney] (UNSW), Icahn School of Medicine at Mount Sinai [New York] (MSSM), University of Peking, Peking University [Beijing], Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Ordu University - Ordu Üniversitesi, Lanzhou University, Universidad del Tolima, Research Centre for Forestry and Wood, Consiglio per la Ricerca in Agricoltura e l’analisi dell’economia agraria = Council for Agricultural Research and Economics (CREA), Brazilian Agricultural Research Corporation (Embrapa), Universidade de São Paulo = University of São Paulo (USP), Centro Agronomico Tropical de Investigacion y Ensenanza (CATIE), Queensland University of Technology [Brisbane] (QUT), University of Sussex, Harvard University, Institute for Alpine Environment, European Academy of Bozen-Bolzano (EURAC), Étude et compréhension de la biodiversité (ECODIV), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU), Laboratoire de Physique Atmosphérique et Planétaire (LPAP), Université de Liège, Université de Sherbrooke (UdeS), Station d'écologie théorique et expérimentale (SETE), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Observatoire Midi-Pyrénées (OMP), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Centre National de la Recherche Scientifique (CNRS), Centre d’Ecologie Fonctionnelle et Evolutive (CEFE), Université Paul-Valéry - Montpellier 3 (UPVM)-École Pratique des Hautes Études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro - Montpellier SupAgro, University of Manchester [Manchester], Universidade Estadual de Campinas = University of Campinas (UNICAMP), Macquarie University, Universidade Federal do Rio Grande do Norte [Natal] (UFRN), Universidad Rey Juan Carlos [Madrid] (URJC), Universidad Nacional de la Patagonia Austral (UNPA), Universidade Regional de Blumenau (FURB), INIA-CIFOR, Southern Illinois University [Carbondale] (SIU), Center for Biodiversity Management, Instituto Federal de Educação Ciência e Tecnologia do Cearà, The Morton Arboretum, United States Department of Agriculture (USDA), Swiss Federal Institute of Technology, Aarhus University [Aarhus], Smithsonian Conservation Biology Institute, Centre Supérieur de la Recherche Scientifique (CSIC), Centre Supérieur de la Recherche Scientifique, Universidad del Rosario [Bogota], Norwegian University of Science and Technology [Trondheim] (NTNU), Norwegian University of Science and Technology (NTNU), Université Paris Sud (Paris 11), Senckenberg Research Institutes and Natural History Museums, Universidad de Chile = University of Chile [Santiago] (UCHILE), Joint Global Change Research Institute, Pacific Northwest National Laboratory (PNNL)-University of Maryland [College Park], Smithsonian Tropical Research Institute, University of Liege, Université de Liège - Gembloux, Institut Pasteur de Shanghai, Académie des Sciences de Chine - Chinese Academy of Sciences (IPS-CAS), Réseau International des Instituts Pasteur (RIIP), University of Bristol [Bristol], University of the Witwatersrand [Johannesburg] (WITS), Norwegian University of Life Sciences (NMBU), Murdoch University, Carnegie Museum of Natural History [Pittsburgh], Transilvania University of Brasov, Martin-Luther-University Halle-Wittenberg, Senckenberg Biodiversity and Climate Research Centre (SBiK-F), Goethe-Universität Frankfurt am Main-Senckenberg – Leibniz Institution for Biodiversity and Earth System Research - Senckenberg Gesellschaft für Naturforschung, Leibniz Association-Leibniz Association, Universität für Bodenkultur Wien = University of Natural Resources and Life [Vienne, Autriche] (BOKU), Santa Catarina State University (UDESC), University Centre Myerscough, Kiel University, Florida International University [Miami] (FIU), Division of Plant Ststematic and Ecology, Biology department, Université Catholique de Louvain = Catholic University of Louvain (UCL), University of Applied Sciences of Weihenstephan, Four Peaks Environmental Science and Data Solutions, Norsk institutt for bioøkonomi=Norwegian Institute of Bioeconomy Research (NIBIO), Kochi University of Technology (KUT), University of Illinois [Chicago] (UIC), University of Illinois System, Universitat de Barcelona (UB), Kyoto University, Tyumen State University, Oak Ridge National Laboratory [Oak Ridge] (ORNL), UT-Battelle, LLC, Universitat Politècnica de Catalunya [Barcelona] (UPC), Stanford University, University of Edinburgh, Polish Academy of Sciences (PAN), Philips Research Europe - Hamburg, Sector Medical Imaging Systems, Philips Research, Institute for Systematic Botany and Ecology, Universität Ulm - Ulm University [Ulm, Allemagne], Ecosystèmes, biodiversité, évolution [Rennes] (ECOBIO), Université de Rennes (UR)-Institut Ecologie et Environnement (INEE), Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Observatoire des Sciences de l'Univers de Rennes (OSUR), Université de Rennes (UR)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Rennes 2 (UR2)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Rennes 2 (UR2)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Centre National de la Recherche Scientifique (CNRS), Universität Bayreuth, University of Copenhagen = Københavns Universitet (UCPH), Guangxi Normal University, University College of London [London] (UCL), Hobart - Tasmania 7001, University of Venda [South Africa] (UNIVEN), University of Melbourne, Philipps Universität Marburg = Philipps University of Marburg, Agrosystèmes Cultivés et Herbagers (ARCHE), Institut National de la Recherche Agronomique (INRA)-École nationale supérieure agronomique de Toulouse (ENSAT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT), Natural Resource Operations and Rural Development, Humboldt State University (HSU), Charles University [Prague] (CU), Karlsruhe Institute of Technology (KIT), Samara National Research University, Institute of Plant Sciences, Forestry and Forest Products Research Institute (FFPRI), Kenyon College, University of Garmian, State University of New York (SUNY), Institute for Biodiversity and Ecosystem Dynamics (IBED), University of Amsterdam [Amsterdam] (UvA), Universidad Nacional del Comahue [Neuquén] (UNCOMA), IT University of Copenhagen (ITU), Agricultural Research Organization, Landscape Ecology Group, University of Oldenburg, Western Carolina University, Xi'an Jiaotong-Liverpool University [Suzhou], Hokkaido University [Sapporo, Japan], Yokohama National University, Technische Universität Munchen - Université Technique de Munich [Munich, Allemagne] (TUM), Institut d Estudis Andorrans, Smithsonian Environmental Research Center (SERC), Humboldt University Of Berlin, University of California [Los Angeles] (UCLA), Department of Biodiversity, Macroecology and Biogeography, Yamagata University, Jomo Kenyatta University of Agriculture and Technology (JKUAT), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut de Recherche pour le Développement (IRD)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro - Montpellier SupAgro, Université du Québec en Abitibi-Témiscamingue (UQAT), University of Saskatchewan [Saskatoon] (U of S), University of Natural Resources and Life Sciences, Institute of Mountain Risk Engineering - Vienna, Austria, University of Wyoming (UW), Département Performances des systèmes de production et de transformation tropicaux (Cirad-PERSYST), Nelson Mandela University [Port Elizabeth], University of Wisconsin - Eau Claire, Naturalis Biodiversity Center [Leiden], Département de biologie [Sherbrooke] (UdeS), Faculté des sciences [Sherbrooke] (UdeS), Université de Sherbrooke (UdeS)-Université de Sherbrooke (UdeS), Yangzhou University, Leipzig University, University Pablo de Olavide, Shanghai Jiao Tong University [Shanghai], Royal Botanical Gardens, Masaryk University [Brno] (MUNI), Department of Physiology, University of Debrecen Egyetem [Debrecen]-Research Centre for Molecular Medicine-Medical and Health Science Centre, Global Change Research Centre (CzechGlobe), Université du Québec à Trois-Rivières (UQTR), Natural Resources Institute Finland (LUKE), Universidade Federal de Alagoas = Federal University of Alagoas (UFAL), Lakehead University, Stockholm University, Universidad Nacional del Litoral [Santa Fe] (UNL), Universidade Federal do Paraná (UFPR), Bangor University, Universidad Autonoma del Estado de Morelos (UAEM), Manaaki Whenua – Landcare Research [Lincoln], Gorongosa National Park, Université de Montréal (UdeM), Tel Aviv University (TAU), University of Queensland [Brisbane], University of Wisconsin-Madison, University of Maine, Holden Arboretum, Hawkesbury Institute for he Environment, Laboratoire d'Ecologie Végétale et Biogéochimie, Université libre de Bruxelles (ULB), University of British Columbia (UBC), Research School of Biology, Universidade Federal de Pernambuco [Recife] (UFPE), School of Geosciences [Edinburgh], Ecology and Evolutionary Biology [Tucson] (EEB), University of Debrecen, Northern Forestry Centre, Canadian Forest Service - CFS (CANADA), University of Illinois at Urbana-Champaign [Urbana], Data61 [Canberra] (CSIRO), Australian National University (ANU)-Commonwealth Scientific and Industrial Research Organisation [Canberra] (CSIRO), University of Debrecen Egyetem [Debrecen], University of Vermont [Burlington], Fundação Zoobotânica do Rio Grande do Sul, University of Montana, Institut de RadioAstronomie Millimétrique (IRAM), Centre National de la Recherche Scientifique (CNRS), University of Freiburg [Freiburg], University of Hawaii, Institut Français de Pondichéry (IFP), Ministère de l'Europe et des Affaires étrangères (MEAE)-Centre National de la Recherche Scientifique (CNRS), Oklahoma State University [Stillwater] (OSU), Osaka City University, Charles Darwin Research Station (CDRS), Charles Darwin Foundation, Los Alamos National Laboratory (LANL), Zhejiang Normal University, European Academy of Bolzano, Universidad Distrital Francisco Jose de Caldas [Bogota], University of Bayreuth, Institute of Biology of Komi Scientific Centre of the Ural Branch of the Russian Academy of Sciences, Russian Academy of Sciences [Moscow] (RAS), CSIRO Land and Water, Commonwealth Scientific and Industrial Research Organisation [Canberra] (CSIRO), University of Canberra, CEH, Department of Systems and Science, Graduate School of Informatics, Kyoto University-Kyoto University, Departamento de Telemática, Faculdade de Engenharia Elétrica e de Computação (DT/FEEC), Universidad Nacional Autónoma de México = National Autonomous University of Mexico (UNAM), Moscow State University, Vrije Universiteit Amsterdam [Amsterdam] (VU), Meijo University, Institute of Ecology and Earth Sciences [Tartu], Astronomical Institute of the Czech Academy of Sciences (ASU / CAS), University of Nijmegen, University of New England (UNE), The James Hutton Institute, Democritus University of Thrace (DUTH), Institute of Ecology and Earth Sciences, University of Tartu, Spanish National Research Council (CSIC), Senckenberg Research Institute and Natural History Museum, University of Vienna [Vienna], Center for Desertification Research (CIDE), Universitat de València (UV), Universidad Autónoma de Madrid (UAM), Université de Jaén, National Institute for Research and Development in Forestry, Department of Plant Production (University of Milan), Tartu Observatory, Botanical Garden of the Samara University, Forschungszentrum Jülich GmbH, Tallinn University, Universität Regensburg (REGENSBURG), Universität Regensburg, School of Social Sciences [Cardiff], Cardiff University, Estonian University of Life Sciences (EMU), Sch Life Sci Weihenstephan, Arizona State University [Tempe] (ASU), Department of Forest Resources, University of Minnesota System-University of Minnesota System, Research Institute for Networks and Communications Engineering (RINCE), Dublin City University [Dublin] (DCU)-Science Foundation Ireland-Enterprise Ireland-Higher Education Authority-School of Electronic Engineering, Southwest University of Science and Technology [Mianyang] (SWUST), Universidade Federal do Acre (UFAC), Berlin-Brandenburg Institute of Advanced Biodiversity Research (BBIB), Centre méditérannéen de médecine moléculaire (C3M), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Mississippi State University [Mississippi], University of Southampton, Yale University [New Haven], Brookhaven National Laboratory [Upton, NY] (BNL), UT-Battelle, LLC-Stony Brook University [SUNY] (SBU), State University of New York (SUNY)-State University of New York (SUNY)-U.S. Department of Energy [Washington] (DOE), East Stroudsburg University, INDEHESA, Forestry School, Universidad de Extremadura - University of Extremadura (UEX), Institute of Physical Geography [Frankfurt am Main], Universität Zürich [Zürich] = University of Zurich (UZH), Lake Ecosystems Group [Lancaster, U.K.] (Centre for Ecology & Hydrology), Lancaster Environment Centre [Lancaster, U.K.], University of Valladolid, Norwegian Institute for Nature Research (NINA), Universidad Nacional de Colombia [Bogotà] (UNAL), Instituto de Recursos Naturales y Agrobiología de Salamanca (IRNASA), Universidade de Coimbra [Coimbra], Algoma University, Senckenberg biodiversität und klima forschungszentrum (BIK-F), Forschungsinstitut Senckenberg (SGN), University of Nottingham, UK (UON), University of Würzburg = Universität Würzburg, Agence Française de Sécurité Sanitaire des Aliments (AFSSA), Herencia, Kirstenbosch Research Centre, South African National Biodiversity Institute, Federal University of Pernambuco [Recife], Sharplex Services, University of Hohenheim, Komarov Botanical Institute RAS, Center for Sustainability Science, Hokkaido, Département de Biologie, University of Regina (UR), Technische Universität Ilmenau (TU ), Universidade de Lisboa = University of Lisbon (ULISBOA), Universidade Federal de Lavras = Federal University of Lavras (UFLA), Università degli Studi di Padova = University of Padua (Unipd), Gothenburg Global Biodiversity Centre, Department of Biology [Gainesville] (UF|Biology), Texas Tech University [Lubbock] (TTU), Florida Museum of Natural History [Gainesville], KU Leuven, Embrapa Recursos Genéticos e Biotecnologia [Brasília], Universiteit Leiden, University of California [Riverside] (UC Riverside), Pacific Northwest National Laboratory (PNNL), University of Natural Resources and Applied Life Sciences, Vienna, (BOKU) and Competence Centre Wood K plus, University of Novi Sad, Instituto Nacional de Investigaciones en Biodiversidad y Medioambiente [Bariloche] (INIBIOMA-CONICET), Consejo Nacional de Investigaciones Científicas y Técnicas [Buenos Aires] (CONICET)-Universidad Nacional del Comahue [Neuquén] (UNCOMA), Slovak Academy of Sciences (SAS), Technical University in Zvolen (TUZVO), Faculty of Forestry and Wood Sciences, Czech University of Life Sciences Prague (CZU), University of Aberdeen, University of Maryland System, Universität Innsbruck [Innsbruck], Estacion Experimental de Zonas Aridas, Hacettepe University = Hacettepe Üniversitesi, Centre for Forest Research (CFR), Université du Québec à Montréal = University of Québec in Montréal (UQAM), Bioversity International [Montpellier], Bioversity International [Rome], Consultative Group on International Agricultural Research [CGIAR] (CGIAR)-Consultative Group on International Agricultural Research [CGIAR] (CGIAR), Department of Animal and Plant Sciences [Sheffield], University of Sheffield [Sheffield], The School for Field Studies, Quantum Optics and Laser Science, Blackett Laboratory, Blackett Laboratory, Imperial College London-Imperial College London, University of Delaware [Newark], Université Clermont Auvergne [2017-2020] (UCA [2017-2020]), Biodiversity and Ecosystem Services Research Group, Stellenbosch University, Czech University of Life Science, Aristotle University of Thessaloniki, Osaka Natural History Center, Ural State Forest Engineering University, University of New Hampshire (UNH), University of Calgary, Catholic University of Leuven - Katholieke Universiteit Leuven (KU Leuven), Hawkesbury Institute for the Environment [Richmond] (HIE), Computational & Applied Vegetation Ecology (CAVElab), Dept Forest & Water Management, Lab Forestry, Museu Paraense Emílio Goeldi, Federal University of Para - Universidade Federal do Pará - UFPA [Belém, Brazil] (UFPA), State Key Laboratory of Natural and Biomimetic Drugs, Fudan University [Shanghai], Department of Ecological Science [Amsterdam], Vrije Universiteit Brussel (VUB), Laboratoire de Biologie des Ligneux et des Grandes Cultures (LBLGC), Université d'Orléans (UO)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Department of Biology, Free University of Bozen-Bolzano, Dpt Biological Sciences, Macquarie University, Duke University [Durham], IFP Energies nouvelles (IFPEN), Department of Primary Industries, Graduate School of Integrated Arts and Sciences, Hiroshima University, Université de Tsukuba = University of Tsukuba, SUNY College of Environmental Science and Forestry (SUNY-ESF), Biological Sciences Department (BIOLOGICAL SCIENCES DEPARTMENT), Nanjing University (NJU), National Taiwan University [Taiwan] (NTU), Zhejiang University, Beijing Forestry University, Institut National Polytechnique Félix Houphouët-Boigny, Universität Leipzig, Max Planck Fellow Program for Christian Wirth, the International Programme of Biodiversity Science (DIVERSITAS), the International Geosphere‐Biosphere Programme (IGBP), Future Earth, the French Foundation for Biodiversity Research (FRB), and GIS ‘Climat, Environnement et Société’ France, JENS KATTGE, MAX PLANCK INSTITUTE FOR BIOGEOCHEMISTRY, GERMANY, ELLEN L. FRY, UNIVERSITY OF LIÈGE, BELGIUM, NIKOLAOS M. FYLLAS, UNIVERSITY OF THE AEGEAN, GREECE, GERHARD BÖNISCH, MAX PLANCK INSTITUTE FOR BIOGEOCHEMISTRY, GERMANY, SUSANNE TAUTENHAHN, MAX PLANCK INSTITUTE FOR BIOGEOCHEMISTRY, JENA, GERMANY, GIJSBERT D. A. WERNER, UNIVERSITY OF OXFORD, OXFORD, UK, TUOMAS AAKALA, UNIVERSITY OF HELSINKI, FINLAND, MEHDI ABEDI, TARBIAT MODARES UNIVERSITY, IRAN, ALICIA T. R. ACOSTA, UNIVERSITY OF ROMA TRE, ITALY, GEORGE C. ADAMIDIS, UNIVERSITY OF BERN, SWITZERLAND, KAIRI ADAMSON, UNIVERSITY OF TARTU, ESTONIA, MASAHIRO AIBA, TOHOKU UNIVERSITY, JAPAN., CÉCILE H. ALBERT, AIX MARSEILLE UNIV, UNIV AVIGNON, FRANCE., JULIO M. ALCÁNTARA, UNIVERSIDAD DE JAÉN, SPAIN, CAROLINA ALCÁZAR C, Instituto Alexander Von Humboldt, Colombia., HAMADA ALI, SUEZ CANAL UNIVERSITY, EGYPT, BERNARD AMIAUD, UNIVERSITÉ DE LORRAINE, FRANCE., CHRISTIAN AMMER, UNIVERSITY OF GÖTTINGEN, GERMANY, MARIANO M. AMOROSO, UNIVERSIDAD NACIONAL DE RÍO NEGRO, ARGENTINA, MADHUR ANAND, UNIVERSITY OF GUELPH, CANADA., MARIJN BAUTERS, GHENT UNIVERSITY, BELGIUM., ERIKA BAZZATO, UNIVERSITY OF CAGLIARI, ITALY., MICHAEL BECKMANN, Helmholtz Centre for Environmental Research, Germany., HANS BEECKMAN, ROYAL MUSEUM FOR CENTRAL AFRICA, BELGIUM., CARL BEIERKUHNLEIN, UNIVERSITY OF BAYREUTH, GERMANY., RENEE BEKKER, UNIVERSITY OF GRONINGEN, THE NETHERLANDS., JOANA BERGMANN, FREIE UNIVERSITÄT BERLIN, GERMANY., MARCOS BERGMANN CARLUCCI, UFPC, LOGAN BERNER, NORTHERN ARIZONA UNIVERSITY, USA., MARKUS BERNHARDT-RÖMERMANN, FRIEDRICH SCHILLER UNIVERSITY JENA, GERMANY., CHRISTOF BIGLER, ETH ZURICH, SWITZERLAND., FEDERICO BRUMNICH, UNIVERSIDAD NACIONAL DEL LITORAL (FICH-UNL), ARGENTINA, HANS HENRIK BRUUN, UNIVERSITY OF COPENHAGEN, DENMARK, DAVID BRUY, UNIVERSITÉ DE MONTPELLIER, FRANCE, SERRA W. BUCHANAN, UNIVERSITY OF TORONTO SCARBOROUGH, CANADA, ROBERT BUITENWERF, AARHUS UNIVERSITY, DENMARK, DANIEL E. BUNKER, NEW JERSEY INSTITUTE OF TECHNOLOGY, USA, JANA BÜRGER, UNIVERSITY OF ROSTOCK, GERMANY, SABINA BURRASCANO, SAPIENZA UNIVERSITY OF ROME, ITALY, DAVID F. R. P. BURSLEM, UNIVERSITY OF ABERDEEN, UK, BRADLEY J. BUTTERFIELD, NORTHERN ARIZONA UNIVERSITY, USA, CHAEHO BYUN, YONSEI UNIVERSITY, KOREA, MARINA C. SCALON, UFP, MARCO CACCIANIGA, UNIVERSITÀ DEGLI STUDI DI MILANO, ITALY, MARC CADOTTE, UNIVERSITY OF TORONTO SCARBOROUGH, CANADA, MAXIME CAILLERET, AIX?MARSEILLE UNIVERSITY, FRANCE, JAMES CAMAC, THE UNIVERSITY OF MELBOURNE, AUSTRALIA, JESÚS JULIO CAMARERO, INSTITUTO PIRENAICO DE ECOLOGÍA (IPE?CSIC), SPAIN, COURTNEY CAMPANY, COLGATE UNIVERSITY, USA, GIANDIEGO CAMPETELLA, UNIVERSITY OF CAMERINO, ITALY, JUAN ANTONIO CAMPOS, UNIVERSITY OF THE BASQUE COUNTRY UPV/EHU, SPAIN, LAURA CANO-ARBOLEDA, UNIVERSIDAD NACIONAL DE COLOMBIA, COLOMBIA, ROBERTO CANULLO, UNIVERSITY OF CAMERINO, ITALY, MICHELE CARBOGNANI, UNIVERSITY OF PARMA, ITALY, FABIO CARVALHO, LANCASTER UNIVERSITY, UK, BASTIEN CASTAGNEYROL, UNIV. BORDEAUX, FRANCE, JANE A. CATFORD, KING'S COLLEGE LONDON, UK, JEANNINE CAVENDER-BARES, UNIVERSITY OF MINNESOTA, USA, BRUNO E. L. CERABOLINI, UNIVERSITY OF INSUBRIA, ITALY, MARCO CERVELLINI, UNIVERSITY OF BOLOGNA, ITALY, EDUARDO CHACÓN-MADRIGAL, UNIVERSIDAD DE COSTA RICA, COSTA RICA, KENNETH CHAPIN, THE UNIVERSITY OF ARIZONA, USA, SAMANTHA DAWSON, SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES, AREND JACOBUS DE BEER, UNIVERSITY OF PRETORIA, SOUTH AFRICA, ANGEL DE FRUTOS, HELMHOLTZ CENTRE FOR ENVIRONMENTAL RESEARCH, GERMANY, LEANDRO DUARTE, UFRGS, EMILIE DUCOURET, UMR ECOFOG (AGROPARISTECH, CNRS, INRA, UNIVERSITÉ DES ANTILLES, UNIVERSITÉ DE LA GUYANE), FRANCE, STEFAN DULLINGER, UNIVERSITY OF VIENNA, AUSTRIA, DAN F. B. FLYNN, ARNOLD ARBORETUM OF HARVARD UNIVERSITY, USA, VERONIKA FONTANA, INSTITUTE FOR ALPINE ENVIRONMENT, ITALY, KYONG-SOOK CHUNG, JUNGWON UNIVERSITY, KOREA, MILAN CHYTRÝ, MASARYK UNIVERSITY, CZECH REPUBLIC, DANIELA CICCARELLI, UNIVERSITY OF PISA, ITALY, LLUÍS COLL, UNIVERSITY OF LLEIDA, SPAIN, COURTNEY G. COLLINS, UNIVERSITY OF CALIFORNIA RIVERSIDE, USA, LUISA CONTI, UNIVERSITY OF LIFE SCIENCES PRAGUE, CZECH REPUBLIC, DAVID COOMES, UNIVERSITY OF CAMBRIDGE, UK, JOHANNES H. C. CORNELISSEN, VRIJE UNIVERSITEIT, THE NETHERLANDS, WILLIAM K. CORNWELL, EARTH AND ENVIRONMENTAL SCIENCES, AUSTRALIA, PIERMARIA CORONA, CREA – RESEARCH CENTRE FOR FORESTRY AND WOOD, ITALY, MARIE COYEA, UNIVERSITÉ LAVAL, CANADA, JOSEPH CRAINE, JONAH VENTURES, USA, DYLAN CRAVEN, UNIVERSIDAD MAYOR, CHILE, JORIS P. G. M. CROMSIGT, SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES, SWEDEN, ANIKÓ CSECSERITS, MTA CENTRE FOR ECOLOGICAL RESEARCH, HUNGARY, KATARINA CUFAR, UNIVERSITY OF LJUBLJANA, SLOVENIA, MATTHIAS CUNTZ, UNIVERSITÉ DE LORRAINE, FRANCE, ANA CAROLINA DA SILVA, SANTA CATARINA STATE UNIVERSITY, BRAZIL, KYLA M. DAHLIN, MICHIGAN STATE UNIVERSITY, USA, MATTEO DAINESE, INSTITUTE FOR ALPINE ENVIRONMENT, ITALY, IGOR DALKE, INSTITUTE OF BIOLOGY OF KOMI SCIENCE CENTRE OF THE URAL BRANCH OF THE RUSSIAN ACADEMY OF SCIENCES, RUSSIA, MICHELE DALLE FRATTE, UNIVERSITY OF INSUBRIA, ITALY, ANH TUAN DANG-LE, UNIVERSITY HO CHI MINH CITY, VIETNAM, JIRÍ DANIHELKA, MASARYK UNIVERSITY, CZECH REPUBLIC, MASAKO DANNOURA, KYOTO UNIVERSITY, JAPAN, JONATHAN R. DE LONG, NETHERLANDS INSTITUTE OF ECOLOGY, THE NETHERLANDS, BENJAMIN DECHANT, SEOUL NATIONAL UNIVERSITY, REPUBLIC OF KOREA, SYLVAIN DELAGRANGE, INSTITUTE OF TEMPERATE FOREST SCIENCES (ISFORT), CANADA, NICOLAS DELPIERRE, UNIVERSITY OF PARIS?SUD, FRANCE, GÉRALDINE DERROIRE, UNIVERSITÉ DES ANTILLES, FRANCE, ARILDO S. DIAS, UNIVERSITÄT FRANKFURT, GERMANY, MILTON HUGO DIAZ-TORIBIO, UNIVERSITY OF FLORIDA, USA, PANAYIOTIS G. DIMITRAKOPOULOS, UNIVERSITY OF THE AEGEAN, GREECE, MARK DOBROWOLSKI, THE UNIVERSITY OF WESTERN AUSTRALIA, AUSTRALIA, DANIEL DOKTOR, HELMHOLTZ CENTRE FOR ENVIRONMENTAL RESEARCH – UFZ, GERMANY, PAVEL DREVOJAN, MASARYK UNIVERSITY, CZECH REPUBLIC, NING DONG, MACQUARIE UNIVERSITY, AUSTRALIA, JOHN DRANSFIELD, ROYAL BOTANIC GARDENS KEW, UK, STEFAN DRESSLER, DEPARTMENT OF BOTANY AND MOLECULAR EVOLUTION, GERMANY, WALTER DURKA, GERMAN CENTER FOR INTEGRATIVE BIODIVERSITY RESEARCH (IDIV) HALLE?JENA?LEIPZIG, GERMANY, REMKO DUURSMA, WESTERN SYDNEY UNIVERSITY, AUSTRALIA, OLGA DYMOVA, KOMI REPUBLIC, RUSSIA, E-VOJTKÓ, A., UNIVERSITY OF SOUTH BOHEMIA, CZECH REPUBLIC, ROLF LUTZ ECKSTEIN, KARLSTAD UNIVERSITY, SWEDEN, HAMID EJTEHADI, FERDOWSI UNIVERSITY OF MASHHAD, IRAN, JAMES ELSER, UNIVERSITY OF MONTANA, USA, THAISE EMILIO, UNIVERSITY OF CAMPINAS UNICAMP, BRAZIL, KRISTINE ENGEMANN, AARHUS UNIVERSITY, DENMARK, MOHAMMAD BAGHER ERFANIAN, FERDOWSI UNIVERSITY OF MASHHAD, IRAN, ALEXANDRA ERFMEIER, KIEL UNIVERSITY, KIEL, GERMANY, ADRIANE ESQUIVEL-MUELBERT, EARTH AND ENVIRONMENTAL SCIENCES, AUSTRALIA, GERD ESSER, JUSTUS LIEBIG UNIVERSITY, GERMANY, MARC ESTIARTE, SPANISH NATIONAL RESEARCH COUNCIL – CSIC, SPAIN, TOMAS F. DOMINGUES, DEPARTMENT OF BIOLOGY – FFCLRP/USP, BRAZIL, WILLIAM F. FAGAN, UNIVERSITY OF MARYLAND, USA, JAIME FAGÚNDEZ, UNIVERSITY OF A CORUÑA, SPAIN, DANIEL S. FALSTER, EVOLUTION & ECOLOGY RESEARCH CENTRE, AUSTRALIA, YING FAN, RUTGERS UNIVERSITY, USA, JINGYUN FANG, PEKING UNIVERSITY, CHINA, EMMANUELE FARRIS, UNIVERSITY OF SASSARI, ITALY, FATIH FAZLIOGLU, ORDU UNIVERSITY, TURKEY, YANHAO FENG, LANZHOU UNIVERSITY, CHINA, FERNANDO FERNANDEZ-MENDEZ, UNIVERSIDAD DEL TOLIMA, COLOMBIA, CARLOTTA FERRARA, CREA – RESEARCH CENTRE FOR FORESTRY AND WOOD, ITALY, JOICE NUNES FERREIRA, CPATU, ALESSANDRA FIDELIS, (UNESP), RIO CLARO, BRAZIL, BRYAN FINEGAN, CATIE-CENTRO AGRONÓMICO TROPICAL DE INVESTIGACIÓN Y ENSEÑANZA, COSTA RICA, JENNIFER FIRN, QUEENSLAND UNIVERSITY OF TECHNOLOGY (QUT), AUSTRALIA, TIMOTHY J. FLOWERS, UNIVERSITY OF SUSSEX, UK, ESTELLE FOREY, UNIVERSITÉ DE ROUEN, FRANCE, CRISTIANE FORGIARINI, UFRGS, BRAZIL., LOUIS FRANÇOIS, UNIVERSITY OF LIÈGE, BELGIUM., MARCELO FRANGIPANI, UFRGS, BRAZIL, DOROTHEA FRANK, MAX PLANCK INSTITUTE FOR BIOGEOCHEMISTRY, GERMANY, CEDRIC FRENETTE-DUSSAULT, GÉOPOLE DE L'UNIVERSITÉ DE SHERBROOKE, CANADA, GRÉGOIRE T. FRESCHET, PAUL SABATIER UNIVERSITY TOULOUSE, FRANCE, PAUL LEADLEY, UNIVERSITY OF PARIS-SUD, UNIVERSITÉ PARIS-SACLAY, ORSAY, FRANCE, IZABELA ALEIXO, NATIONAL INSTITUTE OF AMAZONIAN RESEARCH (INPA), BRAZIL, SANDRA DÍAZ, UNIVERSIDAD NACIONAL DE CÓRDOBA, ARGENTINA, SANDRA LAVOREL, UNIV. SAVOIE MONT BLANC, LECA, GRENOBLE, FRANCE, IAIN COLIN PRENTICE, IMPERIAL COLLEGE, UK., CAROLYN ANDERSON, UNIVERSITY OF MASSACHUSETTS AMHERST, USA, NIELS ANTEN, WAGENINGEN UNIVERSITY, THE NETHERLANDS, JOSEPH ANTOS, UNIVERSITY OF VICTORIA, CANADA, DEBORAH MATTOS GUIMARÃES APGAUA, JAMES COOK UNIVERSITY, AUSTRALIA, TIA-LYNN ASHMAN, UNIVERSITY OF PITTSBURGH, USA, DEGI HARJA ASMARA, UNIVERSITÉ LAVAL, CANADA, GREGORY P. ASNER, ARIZONA STATE UNIVERSITY, USA., MICHAEL ASPINWALL, UNIVERSITY OF NORTH FLORIDA, USA., OWEN ATKIN, AUSTRALIAN NATIONAL UNIVERSITY, AUSTRALIA., ISABELLE AUBIN, NATURAL RESOURCES CANADA, LARS BAASTRUP-SPOHR, UNIVERSITY OF COPENHAGEN, DENMARK., KHADIJEH BAHALKEH, TARBIAT MODARES UNIVERSITY, IRAN., MICHAEL BAHN, UNIVERSITY OF INNSBRUCK, AUSTRIA., TIMOTHY BAKER, UNIVERSITY OF LEEDS, LEEDS, UK., WILLIAM J. BAKER, ROYAL BOTANIC GARDENS KEW, UK., JAN P. BAKKER, UNIVERSITY OF GRONINGEN, THE NETHERLANDS., DENNIS BALDOCCHI, UNIVERSITY OF CALIFORNIA BERKELEY, USA., JENNIFER BALTZER, WILFRID LAURIER UNIVERSITY, CANADA, ARINDAM BANERJEE, UNIVERSITY OF MINNESOTA, USA., ANNE BARANGER, AGROPARISTECH, FRANCE., JOS BARLOW, LANCASTER UNIVERSITY, UK., DIEGO R. BARNECHE, UNIVERSITY OF EXETER, UK., ZDRAVKO BARUCH, THE UNIVERSITY OF ADELAIDE, AUSTRALIA., DENIS BASTIANELLI, UNIV MONTPELLIER, FRANCE., JOHN BATTLES, UNIVERSITY OF CALIFORNIA AT BERKELEY, USA, WILLIAM BAUERLE, COLORADO STATE UNIVERSITY, USA, SOLVEIG FRANZISKA BUCHER, FRIEDRICH?SCHILLER?UNIVERSITÄT JENA, GERMANY, GAVIN BELFRY, UNIVERSITY OF TENNESSEE, USA., MICHAEL BELLUAU, UNIVERSITÉ DU QUÉBEC À MONTRÉAL, CANADA., MIRELA BELOIU, UNIVERSITY OF BAYREUTH, GERMANY., RAQUEL BENAVIDES, MUSEO NACIONAL DE CIENCIAS NATURALES-CSIC, SPAIN., LAHCEN BENOMAR, UNIVERSITÉ LAVAL, CANADA., MARY LEE BERDUGO-LATTKE, UNIVERSIDAD NACIONAL DE COLOMBIA, COLOMBIA., ERIKA BERENGUER, UNIVERSITY OF OXFORD, UK., RODRIGO BERGAMIN, UFRS, NINA BUCHMANN, ETH ZURICH, ZURICH, SWITZERLAND, ANNE D. BJORKMAN, UNIVERSITY OF GOTHENBURG, SWEDEN., CHRIS BLACKMAN, UNIVERSITÉ CLERMONT-AUVERGNE, FRANCE., CAROLINA BLANCO, UFRGS, BENJAMIN BLONDER, ARIZONA STATE UNIVERSITY, USA., DANA BLUMENTHAL, USDA-ARS RANGELAND RESOURCES & SYSTEMS RESEARCH UNIT, USA., KELLY T. BOCANEGRA-GONZÁLEZ, UNIVERSIDAD DEL TOLIMA, COLOMBIA., PASCAL BOECKX, GHENT UNIVERSITY, BELGIUM., STEPHANIE BOHLMAN, UNIVERSITY OF FLORIDA, USA., KATRIN BÖHNING-GAESE, UNIVERSITÄT FRANKFURT, GERMANY., LAURA BOISVERT-MARSH, UNIVERSITÄT FRANKFURT, GERMANY., WILLIAM BOND, UNIVERSITY OF CAPE TOWN, SOUTH AFRICA., BEN BOND-LAMBERTY, COLLEGE PARK, USA., ARNOUD BOOM, UNIVERSITY OF LEICESTER, UK., COLINE C. F. BOONMAN, RADBOUD UNIVERSITY, THE NETHERLANDS., KAUANE BORDIN, UFRGS, ELIZABETH H. BOUGHTON, ARCHBOLD BIOLOGICAL STATION'S BUCK ISLAND RANCH, USA., VANESSA BOUKILI, UNIVERSITY OF CONNECTICUT, USA, DAVID M. J. S. BOWMAN, UNIVERSITY OF TASMANIA, AUSTRALIA., SANDRA BRAVO, UNIVERSIDAD NACIONAL DE SANTIAGO DEL ESTERO, MARCO RICHARD BRENDEL, UNIVERSITY OF HOHENHEIM, MARTIN R. BROADLEY, UNIVERSITY OF NOTTINGHAM, UK, KERRY A. BROWN, KINGSTON UNIVERSITY, UK., HELGE BRUELHEIDE, MARTIN LUTHER UNIVERSITY HALLE?WITTENBERG, GERMANY, FERNANDO CASANOVES, CATIE-CENTRO AGRONÓMICO TROPICAL DE INVESTIGACIÓN Y ENSEÑANZA, COSTA RICA, F. STUART CHAPIN, UNIVERSITY OF ALASKA FAIRBANKS, USA, STEFANO CHELLI, UNIVERSITY OF CAMERINO, ITALY, SI?CHONG CHEN, ROYAL BOTANIC GARDENS, UK, ANPING CHEN, COLORADO STATE UNIVERSITY, USA, PAOLO CHERUBINI, UNIVERSITY OF BRITISH COLUMBIA, CANADA, FRANCESCO CHIANUCCI, CREA – RESEARCH CENTRE FOR FORESTRY AND WOOD, ITALY, BRENDAN CHOAT, WESTERN SYDNEY UNIVERSITY, AUSTRALIA, GUILHERME G. MAZZOCHINI, UNIVERSITY OF CAMPINAS, CAMPINAS, BRAZIL, SOPHIE GACHET, UNIV AVIGNON, FRANCE, RACHAEL GALLAGHER, MACQUARIE UNIVERSITY, AUSTRALIA, GISLENE GANADE, UFRN, BRAZIL., MARY-CLAIRE GLASENHARDT, THE MORTON ARBORETUM, USA, ALAIN HAMBUCKERS, UNIVERSITY OF LIÈGE, BELGIUM, MASAE ISHIHARA, KYOTO UNIVERSITY, JAPAN, LEONID IVANOV, TYUMEN STATE UNIVERSITY, RUSSIA, LARISSA IVANOVA, TYUMEN STATE UNIVERSITY, RUSSIA., COLLEEN M. IVERSEN, OAK RIDGE NATIONAL LABORATORY, USA, JORDI IZQUIERDO, Universitat Politècnica de Catalunya, Spain, ROBERT B. JACKSON, STANFORD UNIVERSITY, USA, FRANCESCA GANGA, UNIVERSITY OF CAGLIARI, ITALY, PABLO GARCÍA-PALACIOS, UNIVERSIDAD REY JUAN CARLOS, SPAIN, VERÓNICA GARGAGLIONE, UNIVERSIDAD NACIONAL DE LA PATAGONIA AUSTRAL, ARGENTINA, ERIC GARNIER, UNIV. MONTPELLIER, FRANCE, JOSE LUIS GARRIDO, ESTACIÓN EXPERIMENTAL DEL ZAIDÍN, SPAIN, ANDRÉ LUÍS DE GASPER, UNIVERSIDADE REGIONAL DE BLUMENAU, BRAZIL, GUILLERMO GEAIZQUIERDO, INIA?CIFOR, SPAIN, DAVID GIBSON, SOUTHERN ILLINOIS UNIVERSITY CARBONDALE, USA, ANDREW N. GILLISON, CENTER FOR BIODIVERSITY MANAGEMENT, AUSTRALIA, AELTON GIROLDO, INSTITUTO FEDERAL DE EDUCAÇÃO CIÊNCIA E TECNOLOGIA DO CEARÁ, BRAZIL, SEAN GLEASON, WATER MANAGEMENT AND SYSTEMS RESEARCH UNIT, USA, MARIANA GLIESCH, INSTITUTE OF INTEGRATIVE BIOLOGY, SWITZERLAND, EMMA GOLDBERG, UNIVERSITY OF MINNESOTA, USA, BASTIAN GÖLDEL, AARHUS UNIVERSITY, DENMARK, ERIKA GONZALEZ-AKRE, NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY NTNU, NORWAY, JOSE L. GONZALEZ-ANDUJAR, CSIC-INSTITUTE FOR SUSTAINABLE AGRICULTURE (IAS), SPAIN, ANDRÉS GONZÁLEZ-MELO, UNIVERSIDAD DEL ROSARIO, COLOMBIA, ANA GONZÁLEZ-ROBLES, UNIVERSIDAD DE JAÉN, SPAIN, BENTE JESSEN GRAAE, NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY NTNU, NORWAY, ELENA GRANDA, UNIVERSITY OF ALCALÁ, SPAIN, SARAH GRAVES, UNIVERSITY OF FLORIDA, USA, WALTON A. GREEN, HARVARD UNIVERSITY, USA, THOMAS GREGOR, SENCKENBERG RESEARCH INSTITUTE AND NATURAL HISTORY MUSEUM, GERMANY, NICOLAS GROSS, UNIVERSIDAD REY JUAN CARLOS, SPAIN, GREG R. GUERIN, THE UNIVERSITY OF ADELAIDE, AUSTRALIA, ANGELA GÜNTHER, MAX PLANCK INSTITUTE FOR BIOGEOCHEMISTRY, GERMANY, ALVARO G. GUTIÉRREZ, UNIVERSIDAD DE CHILE, CHILE, LILLIE HADDOCK, COLLEGE PARK, USA, ANNA HAINES, THE UNIVERSITY OF MANCHESTER, UK, JEFFERSON HALL, SMITHSONIAN TROPICAL RESEARCH INSTITUTE, REPUBLIC OF PANAMA, WENXUAN HAN, CHINA AGRICULTURAL UNIVERSITY, CHINA, SANDY P. HARRISON, UNIVERSITY OF READING, UK, WESLEY HATTINGH, UNIVERSITY OF THE WITWATERSRAND, SOUTH AFRICA, JOSEPH E. HAWES, ANGLIA RUSKIN UNIVERSITY, UK, TIANHUA HE, CURTIN UNIVERSITY, AUSTRALIA, PENGCHENG HE, CHINESE ACADEMY OF SCIENCES, CHINA, JACOB MASON HEBERLING, CARNEGIE MUSEUM OF NATURAL HISTORY, USA, AVELIINA HELM, UNIVERSITY OF TARTU, ESTONIA, STEFAN HEMPEL, FREIE UNIVERSITÄT BERLIN, GERMANY, JÖRN HENTSCHEL, FRIEDRICH-SCHILLER-UNIVERSITÄT JENA, GERMANY, BRUNO HÉRAULT, UNIVERSITÉ DE MONTPELLIER, FRANCE, ANA-MARIA HERE, TRANSILVANIA UNIVERSITY OF BRASOV, ROMANIA, KATHARINA HERZ, MARTIN LUTHER UNIVERSITY HALLE?WITTENBERG, GERMANY, MYRIAM HEUERTZ, UNIV. BORDEAUX, FRANCE, THOMAS HICKLER, GOETHE UNIVERSITY, GERMANY, PETER HIETZ, UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES, AUSTRIA, PEDRO HIGUCHI, SANTA CATARINA STATE UNIVERSITY, BRAZIL, ANDREW L. HIPP, THE MORTON ARBORETUM, USA, ANDREW HIRONS, UNIVERSITY CENTRE MYERSCOUGH, UK, MARIA HOCK, INSTITUTE FOR ECOSYSTEM RESEARCH/GEOBOTANY, GERMANY, JAMES AARON HOGAN, FLORIDA INTERNATIONAL UNIVERSITY, USA, KAREN HOLL, UNIVERSITY OF CALIFORNIA, USA, OLIVIER HONNAY, PLANT CONSERVATION AND POPULATION BIOLOGY, BELGIUM, KNUT ANDERS HOVSTAD, DEPARTMENT OF LANDSCAPE AND BIODIVERSITY, NORWAY, TOMOAKI ICHIE, KOCHI UNIVERSITY, JAPAN, BORIS IGIC, UNIVERSITY OF ILLINOIS AT CHICAGO, USA, ESTELA ILLA, UNIVERSITAT DE BARCELONA, SPAIN, MARNEY ISAAC, UNIVERSITY OF TORONTO, CANADA, BENJAMIN JACKSON, UNIVERSITY OF EDINBURGH, SCOTLAND, HERVÉ JACTEL, UNIV. BORDEAUX, FRANCE, ANDRZEJ M. JAGODZINSKI, UNIVERSITY OF LIFE SCIENCES, POLAND, UTE JANDT, MARTIN LUTHER UNIVERSITY HALLE-WITTENBERG, GERMANY, STEVEN JANSEN, ULM UNIVERSITY, GERMANY, THOMAS, University of Oxford [Oxford], University of Helsinki, Tarbiat Modaras University, Roma Tre University, Institut National de la Recherche Agronomique (INRA)-Université de Lorraine (UL)-Institut National de la Recherche Agronomique (INRA)-Université de Lorraine (UL), Centre for Biodiversity and Sustainable Land-use, University of Göttingen, Göttingen, Germany, Department of Biology, University of North Florida, Jacksonville, FL, USA, University of Copenhagen = Københavns Universitet (KU)-University of Copenhagen = Københavns Universitet (KU), Department of Range Management, Faculty of Natural Resources and Marine Sciences, Tarbiat Modares University, Noor, Iran, University of Innsbruck, School of Geography, University of Leeds, Leeds, UK, Centre for Ecology and Conservation, College of Life and Environmental Sciences, University of Exeter, Penryn, UK., School of Biological Sciences, The University of Adelaide, Adelaide, SA, Australia, Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), University of California at Berkeley, Berkeley, CA, USA, Department of Green Chemistry and Technology, Ghent University, Gent, Belgium, Department of Environment, Ghent University, Gent, Belgium, Department of Life and Environmental Sciences, Botany Division, University of Cagliari, Cagliari, Italy, Museo Nacional de Ciencias Naturales-CSIC, Madrid, Spain, Environmental Change Institute, University of Oxford, Oxford, UK, Institut für Biologie, Freie Universität Berlin, Berlin, Germany, Department of Biological and Environmental Sciences, University of Gothenburg, Gothenburg, Sweden, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil, Universiteit Gent = Ghent University [Belgium] (UGENT), School of Geography, Geology and Environment, University of Leicester, Leicester, UK, Institute of Landscape and Plant Ecology, University of Hohenheim, Stuttgart, Germany, Institute of Biology/Geobotany and Botanical Garden, Martin Luther University Halle-Wittenberg, Halle, Germany, German Center for Integrative Biodiversity Research (iDiv) Halle-Jena- Leipzig, Leipzig, Germany, University of Toronto [Scarborough, Canada], Faculty of Agricultural and Environmental Sciences, University of Rostock, Rostock, Germany, Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome], Dipartimento di Bioscienze, Università degli Studi di Milano, Milano, Italy, Department of Plant Biology and Ecology, University of the Basque Country UPV/ EHU, Bilbao, Spain, Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parma, Italy, Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy, BIGEA, Department of Biological, Geological and Environmental Sciences, Alma Mater Studiorum – University of Bologna, Bologna, Italy, Escuela de Biología, Universidad de Costa Rica, San José, Costa Rica, The University of Arizona, Tucson, AZ, USA, University of Alaska [Anchorage], Royal Botanic Gardens, Kew, Department of Biology, University of Pisa, Pisa, Italy, Department of Plant Sciences, University of Cambridge, Cambridge, UK, Biotechnical Faculty, University of Ljubljana, Ljubljana, Slovenia, Institut National de la Recherche Agronomique (INRA)-Université de Lorraine (UL)-AgroParisTech, Department of Plant and Soil Sciences, University of Pretoria, Pretoria, South Africa, Department of Landscape Architecture and Rural Systems Engineering, Seoul National University, Seoul, Republic of Korea, Department of Botany and Biodiversity Research, University of Vienna, Department of Environmental and Life Sciences – Biology, Karlstad University, Quantitative Plant Ecology and Biodiversity Research Laboratory, Department of Biology, Faculty of Science, Ferdowsi University of Mashhad, Justus Liebig University, Justus-Liebig-Universität Gießen (JLU), University of Sassari, Consiglio per la Ricerca in Agricoltura e l’analisi dell’economia agraria (CREA), Universidade de São Paulo (USP), Harvard University [Cambridge], Federal University of Rio Grande do Sul, Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Observatoire Midi-Pyrénées (OMP), Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD), Université Paul-Valéry - Montpellier 3 (UPVM)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), University of Campinas [Campinas] (UNICAMP), University of Cagliari, Universidad de Chile, University of Natural Resources and Life Sciences (BOKU), University of California, Norwegian Institute of Bioeconomy Research (NIBIO), Kyoto University [Kyoto], Centre National de la Recherche Scientifique (CNRS)-Observatoire des Sciences de l'Univers de Rennes (OSUR)-Institut Ecologie et Environnement (INEE), Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES), University of Copenhagen = Københavns Universitet (KU), University of Venda, Philipps University of Marburg, Institut National de la Recherche Agronomique (INRA)-École nationale supérieure agronomique de Toulouse [ENSAT]-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, State University of New York, Stonybrook, IT University of Copenhagen, Smithsonian Environmental Research Center, Humboldt University of Berlin, Georg-August-University [Göttingen], Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut de Recherche pour le Développement (IRD)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Nelson Mandela Metropolitan University [Port Elizabeth, South Africa], Netherlands Centre for Biodiversity Naturalis, University of Leipzig [Leipzig, Allemagne], Unité d'Agronomie, University of Debrecen-Research Centre for Molecular Medicine-Medical and Health Science Centre, Global Change Research Institute, University of California [Berkeley], Natural resources institute Finland, Universita degli Studi di Cagliari [Cagliari], Tel Aviv University [Tel Aviv], Oklahoma State University [Stillwater], Kyoto University [Kyoto]-Kyoto University [Kyoto], Universidade Estadual de Campinas (UNICAMP), Universidad Nacional Autónoma de México (UNAM), Vrije universiteit = Free university of Amsterdam [Amsterdam] (VU), Universidad Autonoma de Madrid (UAM), University of Parma = Università degli studi di Parma [Parme, Italie], University of Milan, Forschungszentrum Juelich, Université Nice Sophia Antipolis (... - 2019) (UNS), U.S. Department of Energy [Washington] (DOE)-UT-Battelle, LLC-Stony Brook University [SUNY] (SBU), State University of New York (SUNY)-State University of New York (SUNY), University of Extremadura, University of Göttingen - Georg-August-Universität Göttingen, Universidade de Lisboa (ULISBOA), Federal University of Lavras, Universita degli Studi di Padova, Leiden University, University of California [Riverside] (UCR), Ferdowsi University of Mashhad, Museo Nacional de Ciencias Naturales (MNCN), Departments of Botany and Zoology, Federal University of Para - Universidade Federal do Para [Belem - Brésil], Institut National de la Recherche Agronomique (INRA)-Université d'Orléans (UO), Institut national polytechnique Félix Houphouët-Boigny, Universität Leipzig [Leipzig], Institut National de la Recherche Agronomique (INRA)-Université Clermont Auvergne (UCA), Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut de Recherche pour le Développement (IRD)-Institut National de la Recherche Agronomique (INRA), Consejo Nacional de Investigaciones Científicas y Técnicas, Instituto Multidisciplinario de Biología Vegetal (IMBIV), and Factulad de Ciencias Exactas, Físicas y Naturales, Universidad Nacional de Córdoba, Córdoba, Argentina, Laboratoire d'Ecologie Alpine (LECA), Centre National de la Recherche Scientifique (CNRS)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Université Joseph Fourier - Grenoble 1 (UJF)-Université Grenoble Alpes (UGA), Imperial College London, London SW7 2AZ, UK., Department of Zoology, University of Oxford, Oxford, UK, Balliol College, University of Oxford, Oxford, UK, University of Roma Tre, Rome, Italy, Biodiversity Conservation Laboratory, Department of Environment, University of the Aegean, Mytilene, Greece, Institute of Ecology and Evolution, University of Bern, Bern, Switzerland, Tartu Observatory, University of Tartu, Tartumaa, Estonia, Graduate School of Life Sciences, Tohoku University, Sendai, Japan, Centre National de la Recherche Scientifique (CNRS)-Institut de recherche pour le développement [IRD] : UMR237-Aix Marseille Université (AMU)-Avignon Université (AU), Universidad de Jaén, Jaén, Spain, UMR Nancy-Université- INRA Agronomie et Environnement Nancy-Colmar, Nancy Université, Conicet-Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina, Environmental Sciences, Guelph, University of Massachusetts Amherst, Amherst, MA, USA, Wageningen University and Research Center (WUR), University of Victoria, Victoria, BC, Canada, Department of Ecology, University of Innsbruck, Innsbruck, Austria, Department of Biological Sciences-Lancaster University, Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Helmholtz Centre for Environmental Research (UFZ), School of Informatics, Computing, and Cyber Systems, Northern Arizona University, Flagstaff, AZ, USA, Université Clermont Auvergne (UCA)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Universiteit Gent [Ghent], School of Forest Resources and Conservation, University of Florida, Gainesville, FL, USA, University of Tasmania, Hobart, Tas., Australia, AMAP, IRD, Herbier de Nouvelle-Calédonie, Nouméa, New Caledonia, Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut de Recherche pour le Développement (IRD [France-Sud])-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Friedrich-Schiller-Universität Jena, Jena, Germany, Università degli Studi di Roma 'La Sapienza' [Rome], wiss Federal Institute for Forest, Snow and Landscape Research WSL, Birmensdorf, Switzerland, Consejo Superior de Investigaciones Científicas [Spain] (CSIC), Tropical Agricultural Centre for Research and Higher Education (CATIE), Tropical Agricultural Centre for Research and Higher Education, Univ. Bordeaux, INRAE, BIOGECO, Cestas, France, Department of Ecology, Evolution, and Behavior, University of Minnesota, St. Paul, MN, USA, Royal Botanic Gardens, Kew, West Sussex, UK, Department of Biology, Colorado State University, Fort Collins, CO, USA, Hawkesbury Institute for the Environment, Western Sydney University, Sydney, NSW, Australia, Department of Botany and Zoology, Masaryk University, Brno, Czech Republic, Faculty of Environmental Sciences, University of Life Sciences Prague, Praha-Suchdol, Czech Republic, Institute of Botany, Czech Academy of Sciences, Třeboň, Czech Republic, Department of Wildlife, Fish and Environmental Studies, Swedish University of Agricultural Sciences, Umeå, Sweden, MTA Centre for Ecological Research, Tihany, Hungary, Swedish Species Information Centre, Swedish University of Agricultural Sciences, Uppsala, Sweden, Université des Antilles (UA)-Centre National de la Recherche Scientifique (CNRS)-Université de Guyane (UG)-AgroParisTech-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad), University of Florida [Gainesville], UFZ - Helmholtz Centre for Environmental Research, School of Geography, Earth and Environmental Sciences – University of Birmingham, Universitat Autònoma de Barcelona [Barcelona] (UAB), University of Ordu, Council for Agricultural Research and Economics (CREA), Université de Sherbrooke [Sherbrooke], Université Paul-Valéry - Montpellier 3 (UM3)-Institut National de la Recherche Agronomique (INRA)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-École pratique des hautes études (EPHE)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), United States Department of Agriculture - USDA (USA), Smithsonian Institution, Carnegie Museum of Natural History, Friedrich-Schiller-Universität Jena, Biodiversité, Gènes et Communautés, Goethe-Universität Frankfurt am Main-Senckenberg Gesellschaft für Naturforschung, University of Natural Resources and Applied Life Sciences (BOKU), Florida International University (FIU), Université Catholique de Louvain (UCL), Stanford University [Stanford], Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut Ecologie et Environnement (INEE), Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Observatoire des Sciences de l'Univers de Rennes (OSUR)-Centre National de la Recherche Scientifique (CNRS), University of Tasmania (UTAS), Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Supérieure Agronomique de Toulouse-Institut National Polytechnique (Toulouse) (Toulouse INP), Charles University [Prague], Ghent University [Belgium] (UGENT), Helmholtz Zentrum für Umweltforschung (UFZ), Hokkaido University, Technical University of Munich (TUM), Wageningen University and Research Centre [Wageningen] (WUR), Georg-August-Universität Göttingen, Western Sydney University (UWS), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut de Recherche pour le Développement (IRD)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Département de Biologie, Université de Sherbrooke, Sherbrooke, QC, Canada, Université de Sherbrooke, Masaryk University, Czech Academy of Sciences [Prague] (ASCR), Natural Resources Institute Finland, Landcare Research [Lincoln], Université de Montréal [Montréal], Université Libre de Bruxelles [Bruxelles] (ULB), Centre National de la Recherche Scientifique (CNRS)-Ministère de l'Europe et des Affaires étrangères (MEAE), French Institute of Pondicherry (IFP), Normal Zhejiang University, Estonian University of Life Sciences, Institute of Biology Bucharest, Romanian Academy, VU University Amsterdam, Astronomical Institute of the Czech Academy of Sciences, Technische Universität München [München] (TUM), University of Parma, Cardiff School of Social Sciences, University of Cardiff, University of Minnesota [Twin Cities], Manaaki Whenua Landcare Research, Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Brookhaven National Laboratory [Upton] (BNL), Stony Brook University [SUNY] (SBU), University of Zürich [Zürich] (UZH), Algoma University [Canada], University of Goettingen, University of Wuerzburg, University of Würzburg, AFSSA, Sherbrooke University, University of Lisbon, Department of Biology (University of Florida), Florida Museum of Natural History, Technical University in Zvolen, University of Zvolen, Fac Forestry & Wood Sci, Université du Québec à Montréal (UQAM), Bioversity International, Consultative Group on International Agricultural Research [CGIAR], Université Clermont Auvergne (UCA), Vrije Universiteit [Brussels] (VUB), University of Tsukuba, Kattge, Jen, Bönisch, Gerhard, Díaz, Sandra, Lavorel, Sandra, Prentice, Iain Colin, Leadley, Paul, Tautenhahn, Susanne, Werner, Gijsbert D A, Aakala, Tuoma, Abedi, Mehdi, Acosta, Alicia Teresa Rosario, Adamidis, George C, Adamson, Kairi, Aiba, Masahiro, Albert, Cécile H, Alcántara, Julio M, Alcázar C, Carolina, Aleixo, Izabela, Ali, Hamada, Amiaud, Bernard, Ammer, Christian, Amoroso, Mariano M, Anand, Madhur, Anderson, Carolyn, Anten, Niel, Antos, Joseph, Apgaua, Deborah Mattos Guimarãe, Ashman, Tia-Lynn, Asmara, Degi Harja, Asner, Gregory P, Aspinwall, Michael, Atkin, Owen, Aubin, Isabelle, Baastrup-Spohr, Lar, Bahalkeh, Khadijeh, Bahn, Michael, Baker, Timothy, Baker, William J, Bakker, Jan P, Baldocchi, Denni, Baltzer, Jennifer, Banerjee, Arindam, Baranger, Anne, Barlow, Jo, Barneche, Diego R, Baruch, Zdravko, Bastianelli, Deni, Battles, John, Bauerle, William, Bauters, Marijn, Bazzato, Erika, Beckmann, Michael, Beeckman, Han, Beierkuhnlein, Carl, Bekker, Renee, Belfry, Gavin, Belluau, Michael, Beloiu, Mirela, Benavides, Raquel, Benomar, Lahcen, Berdugo-Lattke, Mary Lee, Berenguer, Erika, Bergamin, Rodrigo, Bergmann, Joana, Bergmann Carlucci, Marco, Berner, Logan, Bernhardt-Römermann, Marku, Bigler, Christof, Bjorkman, Anne D, Blackman, Chri, Blanco, Carolina, Blonder, Benjamin, Blumenthal, Dana, Bocanegra-González, Kelly T, Boeckx, Pascal, Bohlman, Stephanie, Böhning-Gaese, Katrin, Boisvert-Marsh, Laura, Bond, William, Bond-Lamberty, Ben, Boom, Arnoud, Boonman, Coline C F, Bordin, Kauane, Boughton, Elizabeth H, Boukili, Vanessa, Bowman, David M J S, Bravo, Sandra, Brendel, Marco Richard, Broadley, Martin R, Brown, Kerry A, 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Günther, Angela, Gutiérrez, Alvaro G, Haddock, Lillie, Haines, Anna, Hall, Jefferson, Hambuckers, Alain, Han, Wenxuan, Harrison, Sandy P, Hattingh, Wesley, Hawes, Joseph E, He, Tianhua, He, Pengcheng, Heberling, Jacob Mason, Helm, Aveliina, Hempel, Stefan, Hentschel, Jörn, Hérault, Bruno, Hereş, Ana-Maria, Herz, Katharina, Heuertz, Myriam, Hickler, Thoma, Hietz, Peter, Higuchi, Pedro, Hipp, Andrew L, Hirons, Andrew, Hock, Maria, Hogan, James Aaron, Holl, Karen, Honnay, Olivier, Hornstein, Daniel, Hou, Enqing, Hough-Snee, Nate, Hovstad, Knut Ander, Ichie, Tomoaki, Igić, Bori, Illa, Estela, Isaac, Marney, Ishihara, Masae, Ivanov, Leonid, Ivanova, Larissa, Iversen, Colleen M, Izquierdo, Jordi, Jackson, Robert B, Jackson, Benjamin, Jactel, Hervé, Jagodzinski, Andrzej M, Jandt, Ute, Jansen, Steven, Jenkins, Thoma, Jentsch, Anke, Jespersen, Jens Rasmus Plantener, Jiang, Guo-Feng, Johansen, Jesper Liengaard, Johnson, David, Jokela, Eric J, Joly, Carlos Alfredo, Jordan, Gregory J, Joseph, 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Landcare Research, Institut de recherche en biologie végétale, Université de Montréal, Tel Aviv University, The University of Queensland, CSIRO, Manaaki Whenua – Landcare Research, Université Libre de Bruxelles, The Australian National University, The University of Edinburgh, Universidade Federal de Pernambuco (UFPE), ICREA, UEFP, University of Waterloo, Tulipan s/n, Vrije Universiteit Brussel, University of Illinois at Urbana-Champaign, University of Vermont, Centre for Northern Forest Ecosystem Research, Matieland, University of Freiburg, University of Hawai'i, Université Grenoble-Alpes, French Institute of Pondicherry, Oklahoma State University, Charles Darwin Research Station, University of Idaho, Instituto de Investigación de Recursos Biológicos Alexander von Humboldt, Universidad Distrital Francisco José de Caldas, NORD University, NTNU, Gifu University, Romanian Academy, Tercer Circuito s/n de Ciudad Universitaria, Universidad Nacional Autónoma de México, Moscow Lomonosov State University, Universidad de las Américas, Wageningen Environmental Research, Technische Universität München, University of New England, Democritus University of Thrace, Universidad Austral de Chile, Desertification Research Center (CIDE-CSIC), Universidad Autónoma de Madrid, Instituto Nacional de Tecnología Agropecuaria (INTA), National Institute for Research-Development in Forestry, University of Regensburg, McGill University, Morton Arboretum, Université Rennes 1/CNRS, Université Paul Valéry, Southwest University of Science and Technology, Universitat de Lleida, Universidade Federal do Acre, Manaaki Whenua-Landcare Research, Centre for Ecological Research and Forestry Applications (CREAF), Royal Museum for Central-Africa (RMCA), Mississippi State University, Radboud University Nijmegen, Yale University, Brookhaven National Laboratory, Ciudad Universitaria, University of Zurich, Chastè Planta-Wildenberg, Centre for Ecology & Hydrology (CEH), Canadian Forest Service, University of Valladolid-INIA, University of Lausanne, Norwegian Institute for Nature Research, Oxford University, Instituto de Recursos Naturales y Agrobiología de Salamanca (IRNASA-CSIC), Universidade de Coimbra, Senckenberg Biodiversität und Klima Forschungszentrum (SBiK-F), Palmengarten der Stadt Frankfurt am Main, Research Institute for Humanity and Nature, University of Regina, Technische Universität Ilmenau, Università degli Studi di Padova, Gothenburg Botanical Garden, Texas Tech University, Archbold Biological Station, Universidade Federal do Rio Grande do Norte, Slovak Academy of Sciences, Czech University of Life Sciences, Estación Experimental de Zonas Áridas (CSIC), CIRAD-UMR SELMET-PZZS, Hacettepe University, Utrecht University, Canadian Wood Fibre Centre, University of Sheffield, Silwood Park, MTA-DE Lendület Functional and Restoration Ecology Research Group, University of Delaware, UMR PIAF, MTA-TKI Biodiversity and Ecosystem Services Research Group, University of Illinois, Botanical Garden of Ural Branch of Russian Academy of Sciences, University of New Hampshire, National University of Singapore, Edinburgh University, Florida Institute of Technology, University of Konstanz, Taizhou University, University of Erlangen-Nuremberg, Universidad de Concepcion, Bulgarian Academy of Sciences, Museu Paraense Emilio Goeldi, Universidad de las Fuerzas Armadas (ESPE), Goa University, Pondicherry University, Carl von Ossietzky University of Oldenburg, Cambridge Conservation Initiative, Tsinghua University, Chinese Academy of Forestry, Fujian Normal University, Vrije Universiteit Amsterdam, Maritime and Science Technology Academy, University of Winnipeg, King Saud University, University of California – Irvine, U. S. Geological Survey, Duke University, NSW Department of Primary Industries, SUNY-College of Environmental Science and Forestry, Sorbonne-Université, Laboratório de Ecologia Vegetal (LEVEG), George Washington University, National Taiwan University, Institut National Polytechnique Félix Houphouët-Boigny (INP-HB), University Oldenburg, and Biyoloji
Subjects: [SDE] Environmental Sciences, LIFE-HISTORY, Geography & travel, WOOD DENSITY, plant trait, Biodiversity & Conservation, 05 Environmental Sciences, Growth, 580 Plants (Botany), COMMUNITY COMPOSITION, ROOT TRAITS, Biologiska vetenskaper, Ecological modeling, data coverage, data integration, data representativeness, functional diversity, plant traits, TRY plant trait database, Biodiversity, Ecology, Plants, Access to Information, Ecosystem, data representativene, ddc:910, General Environmental Science, Global and Planetary Change, GLOBAL PATTERNS, food and beverages, LEAF PHOTOSYNTHETIC TRAITS, Biological Sciences, CAVElab, Data processing, ddc:580, [SDE]Environmental Sciences, Biodiversity Conservation, Life Sciences & Biomedicine, INCLINATION ANGLE DISTRIBUTION, Environmental Sciences & Ecology, Ecology and Environment, Database, LITTER DECOMPOSITION, ddc:570, Datenintegration, Environmental Chemistry, DDC 004 / Data processing & computer science, Intraspecific competition, Data integration (Computer science), Science & Technology, Biology and Life Sciences, Plant, 06 Biological Sciences, Environmental factor, Nutrient Network, Biology and Microbiology, FUNCTIONAL TRAITS, DDC 580 / Botanical sciences, Earth and Environmental Sciences, ddc:004, [SDE.BE]Environmental Sciences/Biodiversity and Ecology, Environmental Sciences, RELATIVE GROWTH-RATE
Abstract: Plant traits—the morphological, anatomical, physiological, biochemical and phenological characteristics of plants—determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodiversity conservation, ecosystem and landscape management, restoration, biogeography and earth system modelling. Since its foundation in 2007, the TRY database of plant traits has grown continuously. It now provides unprecedented data coverage under an open access data policy and is the main plant trait database used by the research community worldwide. Increasingly, the TRY database also supports new frontiers of trait-based plant research, including the identification of data gaps and the subsequent mobilization or measurement of new data. To support this development, in this article we evaluate the extent of the trait data compiled in TRY and analyse emerging patterns of data coverage and representativeness. Best species coverage is achieved for categorical traits—almost complete coverage for ‘plant growth form’. However, most traits relevant for ecology and vegetation modelling are characterized by continuous intraspecific variation and trait–environmental relationships. These traits have to be measured on individual plants in their respective environment. Despite unprecedented data coverage, we observe a humbling lack of completeness and representativeness of these continuous traits in many aspects. We, therefore, conclude that reducing data gaps and biases in the TRY database remains a key challenge and requires a coordinated approach to data mobilization and trait measurements. This can only be achieved in collaboration with other initiatives., publishedVersion
Published: 2020

38. Primary results from the STARLINER study of disease behaviour in suspected ILD

Author: Frank Gilberg, Syed Anees, Claudia Valenzuela, Carlo Vancheri, Michael T. Henry, Monica Bengus, Elisabeth Bendstrup, Klaus-Uwe Kirchgaessler, Mirela Mirt, Alessandro G. Fois, Marlies S. Wijsenbeek, Stéphane Jouneau, Catharina C. Moor, Onofre Moran, Erasmus University Medical Center [Rotterdam] (Erasmus MC), Aarhus University Hospital, Universidad Autonoma de Madrid (UAM), University College Cork (UCC), Institut de recherche en santé, environnement et travail (Irset), Université d'Angers (UA)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Università degli Studi di Sassari [Sassari] (UNISS), Queen's University [Kingston, Canada], University of Windsor [Ca], F. Hoffmann-La Roche [Basel], University of Catania [Italy], Universidad Autónoma de Madrid (UAM), Université d'Angers (UA)-Université de Rennes (UR)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), and Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS)
Subjects: Spirometry, medicine.medical_specialty, Primary (chemistry), medicine.diagnostic_test, business.industry, [SDV]Life Sciences [q-bio], Idiopathic pulmonary fibrosis, Disease behaviour, medicine.disease, Internal medicine, Diagnosis, medicine, business, ComputingMilieux_MISCELLANEOUS
Abstract: International audience
Published: 2020

39. Ecosystems

Author: Balzan, Mario V, Hassoun, Abed El Rahman, Aroua, Najet, Baldy, Virginie, Dagher, Magda Bou, Branquinho, Cristina, Dutay, Jean-Claude, El Bour, Monia, Médail, Frédéric, Mojtahid, Meryem, Morán-Ordóñez, Alejandra, Roggero, Pier Paolo, Heras, Sergio Rossi, Schatz, Bertrand, Vogiatzakis, Ioannis N., Zaimes, George N., Ziveri, Patrizia, Malta Council for Science and Technology, National Council for Scientific Research = Conseil national de la recherche scientifique du Liban [Lebanon] (CNRS-L), Université Mohamed Khider de Biskra (BISKRA), Institut méditerranéen de biodiversité et d'écologie marine et continentale (IMBE), Avignon Université (AU)-Aix Marseille Université (AMU)-Institut de recherche pour le développement [IRD] : UMR237-Centre National de la Recherche Scientifique (CNRS), Université Saint-Joseph de Beyrouth (USJ), Centre for Ecology, Evolution and Environmental Changes, Faculty of Sciences, University of Lisbon, Lisbon, Portugal, Laboratoire des Sciences du Climat et de l'Environnement [Gif-sur-Yvette] (LSCE), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Modélisation du climat (CLIM), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Institut National des Sciences et Technologies de la Mer [Salammbô] (INSTM), Centre de Ciència i Tecnologia Forestal de Catalunya (CTFC), Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Department of Biological and Environmental Sciences (DiSTeBA), Uniersity of Salento, Salento, Italy, Open University of Cyprus, Nicosia, Cyprus, UNESCO Chair Con-E-Ect, International Hellenic University, Drama, Greece, Universitat Autònoma de Barcelona (UAB), Cramer W, Guiot J, and Marini K
Subjects: [SDE]Environmental Sciences, ComputingMilieux_MISCELLANEOUS
Abstract: International audience
Published: 2020

40. Positive end-expiratory pressure-induced recruited lung volume measured by volume-pressure curves in acute respiratory distress syndrome: a physiologic systematic review and meta-analysis

Author: Emanuele Turbil, Nicolas Terzi, Claude Guérin, Laurent Argaud, Sharon Einav, Martin Cour, CarMeN, laboratoire, Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Unité de soins intensifs médicaux [CHU Grenoble], Centre Hospitalier Universitaire [Grenoble] (CHU), Université Grenoble Alpes (UGA), Hôpital Edouard Herriot [CHU - HCL], Hospices Civils de Lyon (HCL), Université de Lyon, The Hebrew University of Jerusalem (HUJ), Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), and University of Sassari
Subjects: ARDS, medicine.medical_specialty, Respiratory distress syndrome, Alveolar recruitment, [SDV]Life Sciences [q-bio], Lung recruitment, Critical Care and Intensive Care Medicine, Respiratory distress syndrome, adult/physiopathology, Positive-Pressure Respiration, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Tidal Volume, Humans, Lung volumes, adult/therapy, Prospective Studies, Simplified Acute Physiology Score, Respiratory distress syndrome, adult/therapy, Positive end-expiratory pressure, business.industry, 030208 emergency & critical care medicine, Publication bias, respiratory system, medicine.disease, Confidence interval, 3. Good health, adult/mortality, [SDV] Life Sciences [q-bio], 030228 respiratory system, Relative risk, Meta-analysis, Positive-pressure respiration/therapeutic use, Respiratory distress syndrome, adult/mortality, Systematic Review, adult/physiopathology, business, Lung Volume Measurements
Abstract: Purpose Recruitment of lung volume is often cited as the reason for using positive end-expiratory pressure (PEEP) in acute respiratory distress syndrome (ARDS) patients. We performed a systematic review on PEEP-induced recruited lung volume measured from inspiratory volume-pressure (VP) curves in ARDS patients to assess the prevalence of patients with PEEP-induced recruited lung volume and the mortality in recruiters and non-recruiters. Methods We conducted a systematic search of PubMed to identify studies including ARDS patients in which the intervention of an increase in PEEP was accompanied by measurement of the recruited volume (Vrec increase versus no increase) using the VP curve in order to assess the relation between Vrec and mortality at ICU discharge. We first analysed the pooled data from the papers identified and then analysed individual patient level data received from the authors via personal contact. The risk of bias of the included papers was assessed using the quality in prognosis studies tool and the certainty of the evidence regarding the relationship of mortality to Vrec by the GRADE approach. Recruiters were defined as patients with a Vrec > 150 ml. A random effects model was used for the pooled data. Multivariable logistic regression analysis was used for individual patient data. Results We identified 16 papers with a total of 308 patients for the pooled data meta-analysis and 14 papers with a total of 384 patients for the individual data analysis. The quality of the articles was moderate. In the pooled data, the prevalence of recruiters was 74% and the mortality was not significantly different between recruiters and non-recruiters (relative risk 1.20 [95% confidence intervals 0.88–1.63]). The certainty of the evidence regarding this association was very low and publication bias evident. In the individual data, the prevalence of recruiters was 70%. In the multivariable logistic regression, Vrec was not associated with mortality but Simplified Acute Physiology Score II and driving pressure at PEEP of 5 cmH2O were. Conclusion After a PEEP increment, most patients are recruiters. Vrec was not associated with ICU mortality. The presence of similar findings in the individual patient level analysis and the driving pressure at PEEP of 5 cmH2O was associated with mortality as previously reported validate our findings. Publication bias and the lack of prospective studies suggest more research is required. Electronic supplementary material The online version of this article (10.1007/s00134-020-06226-9) contains supplementary material, which is available to authorized users.
Published: 2020

41. The potential antimalarial efficacy of hemocompatible silver nanoparticles from Artemisia species against P. falciparum parasite

Author: Serenella Medici, Alessandra Pinna, Ioannis Tsamesidis, Cristina D’Avino, Antonella Pantaleo, Elisabetta Avitabile, Nina Senes, Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Pharmacochimie et Biologie pour le Développement (PHARMA-DEV), Institut de Recherche pour le Développement (IRD)-Institut de Chimie de Toulouse (ICT), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT), and Imperial College London
Subjects: Plasmodium, Quantitative Parasitology, [SDV]Life Sciences [q-bio], Metal Nanoparticles, MESH: Silver / chemistry, 02 engineering and technology, Pharmacology, Parasitemia, Silver nanoparticle, chemistry.chemical_compound, MESH: Artemisia/ chemistry, Medical Conditions, MEDIATED SYNTHESIS, MESH: Metal Nanoparticles / ultrastructure, ANTIOXIDANT, ANTIBACTERIAL, Zeta potential, Medicine and Health Sciences, Nanotechnology, MESH: Malaria, Falciparum / drug therapy, Artemisinin, Malaria, Falciparum, IN-VIVO, Protozoans, 0303 health sciences, Quinine, Multidisciplinary, PLASMODIUM-FALCIPARUM, biology, Malarial Parasites, Drugs, Eukaryota, MESH: Metal Nanoparticles / chemistry, 021001 nanoscience & nanotechnology, LEAVES EXTRACT, Multidisciplinary Sciences, Chemistry, MESH: Green Chemistry Technology, Physical Sciences, Science & Technology - Other Topics, Engineering and Technology, Medicine, 0210 nano-technology, GREEN SYNTHESIS, medicine.drug, Research Article, Chemical Elements, Silver, General Science & Technology, MESH: Antimalarials / pharmacology, Science, Plasmodium falciparum, Artemisia annua, 03 medical and health sciences, Antimalarials, Parasite Groups, medicine, Parasitic Diseases, Humans, BIOSYNTHESIS, LEAF EXTRACT, MESH: Antimalarials / chemistry, 030304 developmental biology, Science & Technology, MESH: Silver / pharmacology, MESH: Humans, MESH: Plasmodium falciparum / drug effects, Organisms, Biology and Life Sciences, Green Chemistry Technology, biology.organism_classification, Tropical Diseases, Parasitic Protozoans, Malaria, chemistry, Artemisia, Artesunate, Nanoparticles, Parasitology, Apicomplexa
Abstract: International audience; Malaria represents one of the most common infectious diseases which becoming an impellent public health problem worldwide. Antimalarial classical medications include quinine-based drugs, like chloroquine, and artesunate, a derivative of artemisinin, a molecule found in the plant Artemisia annua. Such therapeutics are very effective but show heavy side effects like drug resistance. In this study, “green” silver nanoparticles (AgNPs) have been prepared from two Artemisia species (A. abrotanum and A. arborescens), traditionally used in folk medicine as a remedy for different conditions, and their potential antimalarial efficacy have been assessed. AgNPs have been characterized by UV-Vis, dynamic light scattering and zeta potential, FTIR, XRD, TEM and EDX. The structural characterization has demonstrated the spheroidal shape of nanoparticles and dimensions under 50 nm, useful for biomedical studies. Zeta potential analysis have shown the stability and dispersion of green AgNPs in aqueous medium without aggregation. AgNPs hemocompatibility and antimalarial activity have been studied in Plasmodium falciparum cultures in in vitro experiments. The antiplasmodial effect has been assessed using increasing doses of AgNPs (0.6 to 7.5 μg/mL) on parasitized red blood cells (pRBCs). Obtained data showed that the hemocompatibility of AgNPs is related to their synthetic route and depends on the administered dose. A. abrotanum-AgNPs (1) have shown the lowest percentage of hemolytic activity on pRBCs, underlining their hemocompatibility. These results are in accordance with the lower levels of parasitemia observed after A. abrotanum-AgNPs (1) treatment respect to A. arborescens-AgNPs (2), and AgNPs (3) derived from a classical chemical synthesis. Moreover, after 24 and 48 hours of A. abrotanum-AgNPs (1) treatment, the parasite growth was locked in the ring stage, evidencing the effect of these nanoparticles to hinder the maturation of P. falciparum. The anti-malarial activity of A. abrotanum-AgNPs (1) on pRBCs was demonstrated to be higher than that of A. arborescens-AgNPs (2).
Published: 2020

42. Wildfire burnt area patterns and trends in Western Mediterranean Europe via the application of a concentration index

Author: Raffaella Lovreglio, Javier Martin-Vide, Christophe Bouillon, Fantina Tedim, Jordi Vendrell, Michele Salis, Vittorio Leone, Dominic Royé, Universidade de Santiago de Compostela [Spain] (USC ), CEGOT - Porto, Universidade do Porto = University of Porto, University of Barcelona, Istituto di Biometeorologia [Sassari] (IBIMET), National Research Council of Italy | Consiglio Nazionale delle Ricerche (CNR), Research, Development and Innovation Area, Pau Costa Foundation Taradell Spain, Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Risques, Ecosystèmes, Vulnérabilité, Environnement, Résilience (RECOVER), Aix Marseille Université (AMU)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Università degli studi della Basilicata [Potenza] (UNIBAS), Universidade do Porto, Consiglio Nazionale delle Ricerche [Roma] (CNR), and Università degli Studi di Sassari [Sassari] (UNISS)
Subjects: Mediterranean climate, Index (economics), Fire regime, business.industry, High variability, Soil Science, Distribution (economics), Climate change, 04 agricultural and veterinary sciences, 010501 environmental sciences, 15. Life on land, Development, 01 natural sciences, Key point, Geography, 13. Climate action, [SDE]Environmental Sciences, 040103 agronomy & agriculture, 0401 agriculture, forestry, and fisheries, Environmental Chemistry, Physical geography, business, 0105 earth and related environmental sciences, General Environmental Science, Teleconnection
Abstract: International audience; The most widely used metrics to characterize wildfire regime and estimate the impact of wildfires are total burnt area (BA) and the number of fire events (FE). However, these are insufficient to analyse the threat to society of a new fire regime characterized by a higher occurrence of very large events. To overcome this weakness, we propose the use of a Concentration Index (CIB) which makes it possible to identify spatio‐temporal patterns. The frequency distribution of BA follows a negative exponential distribution almost everywhere, in which a small minority of FE is responsible of the majority of BA. In this article, the spatio‐temporal behaviour of BA is analysed in Western Mediterranean Europe, with particular focus on Portugal, Spain, France and Italy, using data from the European Forest Fire Information System and national wildfire databases. This is the first time that the CI has been applied to wildfire events. This research shows that, in most Mediterranean European countries, the amount of BA is increasingly related with a lower number of fires. The spatio‐temporal distribution of CIB shows high variability in all of the countries analysed in Europe. Portugal and Spain show increasing significant trends of CIB + 7.6% (p‐value = 0.001) and + 1.3% per decade (p‐value = 0.003). Statistically significant correlations for Portugal, Spain and Italy are also found between the annual CIB and several teleconnection indices. The application of the CIB demonstrates its discriminatory ability, which is a key point in detecting vulnerable areas and temporal trends under climate change.
Published: 2019

43. Hematological, biochemical and antioxidant indices variations in regular blood donors among Mediterranean regions

Author: Evgenia Lymperaki, Claudio Fozza, Agostino Satta, Eleni Vagdatli, Athanasios Lettas, Ioannis Tsamesidis, Polyxeni Nikza, Massimiliano Oggiano, Antonella Pantaleo, University of Sassari, Pharmacochimie et Biologie pour le Développement (PHARMA-DEV), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut de Chimie de Toulouse (ICT-FR 2599), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Institut de Chimie du CNRS (INC)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Institut de Chimie du CNRS (INC)-Institut de Recherche pour le Développement (IRD), International Hellenic University, ΓΕΝΙΚΟ ΝΟΣΟΚΟΜΕΙΟ ΝΑΟΥΣΑΣ = Naoussa General Hospital, Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Institut de Recherche pour le Développement (IRD)-Institut de Chimie de Toulouse (ICT), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), and Université de Toulouse (UT)
Subjects: Adult, Male, Biochemical indices, [SDV]Life Sciences [q-bio], Population, Physiology, Blood Donors, 030204 cardiovascular system & hematology, Health benefits, Antioxidants, Mediterranean population, Body iron, 03 medical and health sciences, 0302 clinical medicine, medicine, Increased iron, Regular blood donation, Humans, General hospital, education, Aged, education.field_of_study, medicine.diagnostic_test, Greece, business.industry, Mediterranean Region, Hematology, Middle Aged, 3. Good health, Antioxidant capacity, Italy, Female, Liver function, Lipid profile, business, 030215 immunology
Abstract: International audience; Background & objectives: One of the most important problems in Mediterranean regions is finding blood donors to overcome the high need of its population. Understanding the health benefits of blood donation frequency will activate more volunteers to donate. The aim of this study variations of hematological and biochemical indices in regular male and female donors from Greece and Italy METHODS: A cross-sectional study consisted of 350 voluntary blood donors (VDs)was conducted in two mediterranean Blood Banks, Greece and Italy. The first one from the General Hospital of Naousa, Greece on samples of 90 regular and 60 first-time blood donors. The second one from AOU Sassari, Sardinia, Italy on convenient samples of 100 first-time samples and 100 regular blood donors. Donors' particulars were obtained from blood bank records. The hematological and biochemical parameters were determined for all donors and Total Antioxidant Status (TAS) only for greek VDs.Results: High frequency blood donation of Greek VDs could be associated with evidence of reduction of body iron stores, reduced oxidative stress and improvement of liver function biomarkers in regular groups. Interestingly, Sardinian regular male VDs presented increased iron stores in compare with the first time VDs. In both Mediterranean populations (Greeks and Italians) the lipid profile of the female regular blood donors has been improved in compare with the first timers.Conclusion: Regular blood donation increases antioxidant capacity and affects positively the hematological parameters and biochemical biomarkers in donors. Gender plays an important role in relation to all hematological and biochemical parameters. Further studies in larger population should evaluate the beneficial-effect of blood donation and promote people to donate more frequent.
Published: 2019

44. Extending Architecture Modeling for Signal Processing towards GPUs

Author: Maxime Pelcat, Antoine Morvan, Saman Payvar, Claudio Rubattu, Jani Boutellier, Tampere University of Technology [Tampere] (TUT), Università degli Studi di Sassari [Sassari] (UNISS), Institut d'Électronique et des Technologies du numéRique (IETR), Université de Nantes (UN)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS), 732105 CERBERO, Nantes Université (NU)-Université de Rennes 1 (UR1), Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Université de Nantes (UN)-Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), and Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS)
Subjects: Profiling (computer programming), Signal processing, Multi-core processor, Computer science, business.industry, Design space exploration, Linear system, Modeling, 020206 networking & telecommunications, Symmetric multiprocessor system, 02 engineering and technology, [SPI]Engineering Sciences [physics], Software, Computer architecture, Architecture, 0202 electrical engineering, electronic engineering, information engineering, 020201 artificial intelligence & image processing, business, ComputingMilieux_MISCELLANEOUS, Signal processing systems
Abstract: Efficient usage of heterogeneous computing architectures requires distribution of the workload to available processing elements. Traditionally, this mapping is done based on information acquired from application profiling. To reduce the high amount of manual work related to mapping, statistical application and architecture modeling can be applied for automating mapping exploration. Application modeling has been studied extensively, whereas architecture modeling has received less attention. Originally developed for signal processing systems, Linear System Level Architecture (LSLA) is the first architecture modeling approach that clearly distinguishes the underlying computation hardware from software. Up to now, LSLA has covered the modeling of multicore CPUs. This work proposes extending the LSLA model with GPU support, by including the notion of parallelism. The proposed GPU modeling extension is evaluated by performance estimation of three signal processing applications with various workload distributions on a desktop GPU, and a mobile GPU. The measured average fidelity of the proposed model is 93%.
Published: 2019

45. Mechanical Modeling and First Case Study on ITER TF CICC Loading Cases With Upgraded Finite Element Code Simulations

Author: Rebecca Riccioli, Alexandre Torre, Marco Breschi, Damien Durville, Institut de Recherche sur la Fusion par confinement Magnétique (IRFM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Department of Economics, Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Laboratoire de mécanique des sols, structures et matériaux (MSSMat), CentraleSupélec-Centre National de la Recherche Scientifique (CNRS), University of Sassari, Riccioli R., Torre A., Breschi M., and Durville D.
Subjects: AC losses, Electromagnetics, Materials science, Nuclear engineering, 01 natural sciences, Brittleness, [PHYS.MECA.STRU]Physics [physics]/Mechanics [physics]/Structural mechanics [physics.class-ph], 0103 physical sciences, Thermal, TF coil, Current distribution, Electrical and Electronic Engineering, 010306 general physics, Electrical conductor, ComputingMilieux_MISCELLANEOUS, degradation, Solenoidal vector field, Fusion magnet, ITER project, Condensed Matter Physics, Electronic, Optical and Magnetic Materials, Conductor, Upgrade, Magnet, Nb3Sn strand, CICC
Abstract: The strands of the Cable-In-Conduit Conductors (CICCs) for the ITER magnet system TF coils are made of Nb3Sn, which is a brittle and strain-sensitive superconducting material. The strain distribution in the filaments is driven by the cool-down process and the electromagnetic forces acting on the strands in operation. The impact of electromagnetic and thermal warm-up-cool-down cycles on the conductor performance degradation has been investigated experimentally both on short samples in the SULTAN facility and in the solenoidal configuration of the TF Insert tests in the CSMC facility. A deeper understanding on how cyclic loading of the conductor affects its electrical performance could allow one to identify the best working conditions so as to limit the degradation. In this paper, a mechanical model of one last sub-cable (petal) of the TF CICC is presented. The strain distribution in the strands is simulated via a new version of the MULTIFIL finite element code. The effects of the alternate application of thermal and electromagnetics cyclic loading are tentatively analyzed, similarly to experiments performed in the SULTAN facility in the tests of the TFIO1 conductor sample. An upgrade of the model is implemented, concerning the thermal cycle simulation.
Published: 2019

46. Hardware/Software self-adaptation in CPS The CERBERO project approach

Author: César Sanz, Claudio Rubattu, Francesca Palumbo, Pablo Sanchez de Rojas, Maxime Pelcat, Tiziana Fanni, Alfonso Rodriguez, Eduardo de la Torre, R. Lazcano, Antoine Morvan, Luigi Raffo, Carlo Sau, Eduardo Juarez, D. Madroñal, Karol Desnos, Università degli Studi di Sassari [Sassari] (UNISS), Universita degli Studi di Cagliari [Cagliari], Universidad Politécnica de Madrid (UPM), Institut d'Électronique et des Technologies du numéRique (IETR), Nantes Université (NU)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS), Institut Pascal (IP), SIGMA Clermont (SIGMA Clermont)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020]), Ministry of Education, Culture, Sports, Science and Technology, MEXT732105, Pelcat M.Jung M.Pnevmatikatos D.N., Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Università degli Studi di Cagliari = University of Cagliari (UniCa), Université de Nantes (UN)-Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS), SIGMA Clermont (SIGMA Clermont)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre National de la Recherche Scientifique (CNRS), and Université de Nantes (UN)-Université de Rennes 1 (UR1)
Subjects: Informática, HW monitoring, Cyber-Physical Systems, business.industry, Computer science, Cyber-physical system, 02 engineering and technology, Self adaptivity, Self adaptation, Ingeniería Industrial, 020202 computer hardware & architecture, Hardware software, [SPI]Engineering Sciences [physics], Software deployment, Self-adaptivity, 0202 electrical engineering, electronic engineering, information engineering, 020201 artificial intelligence & image processing, Electrónica, HW reconfiguration, Run-time management, Software engineering, business, ComputingMilieux_MISCELLANEOUS, Project approach
Abstract: Cyber-Physical Systems (CPS) are interconnected devices, reactive and dynamic to sensed external and internal triggers. The H2020 CERBERO EU Project is developing a design environment composed by modelling, deployment and verification tools for adaptive CPS. This paper focuses on its efficient support for run-time self-adaptivity.
Published: 2019

47. De l'outil à la représentation du collectif ?: Le dépôt du macro-outillage de creusement dans les cavités artificielles funéraires au Néolithique

Author: Porqueddu, Marie-Élise, Laboratoire méditerranéen de préhistoire Europe-Afrique (LAMPEA), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)-Ministère de la Culture (MC), Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Universita degli Studi di Sassari, and Universitá degli Studi di Sassari
Subjects: Macro-outillage, Techniques de creusement, Macro-lithic tools, [SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistory, Mobilier funéraire, Digging techniques, Néolithique récent-final, Operational chain, Chaîne opératoire, [SHS.ANTHRO-SE]Humanities and Social Sciences/Social Anthropology and ethnology, Rock-cut tomb, Hypogées, Neolithic & Chalcolithic Archaeology
Abstract: http://journals.openedition.org/tc/10786; International audience; The rock-cut tombs are present in several regions of the western Mediterranean at the end of the Neolithic period. Their architecture can be specific and their large number in some territories question their development and the techniques mobilised in their implementation. Several tools used during the various digging phases of these underground architectures are thus known. They are present in various contexts both in Sardinia and in the South of France. These artefacts are not randomly abandoned within them but deposited in particular forms. The digging material is made of a simple tooling manufactured from an opportunistic shaping operational chain. The presence, in the artificial cavities, of deposits of the instruments used originally to dig them is significant and undoubtedly has different meanings. Several interpretations have been proposed in the literature, generally evolving according to the study cases, ranging from a deposit in connection with the deceased to a collective deposit related to the architecture.We therefore propose a comparative analysis of this practice through the study of several sites and types of data, in order to offer an overview of this phenomenon and to question the symbolic value of this act. The deposit in hypogea, of tools that have been used during the digging process of these structures also focuses the reflection on the digging phase and the setting up of the hypogea to which the tools are related, and likewise, on the importance of the symbolic representation conveyed by the construction of such monuments within the community itself. Digging hypogea requires a significant joint collective endeavour, probably mirrored by a large organization of human groups. The deposit of the tools used for this collective activity, during which a large number of people belonging to the group, or even persons coming from outside, participate can be related to the will, the wish, to represent this aspect of the group. It seals a major moment for the community during which significant efforts are made by it.; Pour consulter l'article intégral : http://journals.openedition.org/tc/10786Les cavités artificielles hypogées sont présentes dans plusieurs régions de Méditerranée occidentale à la fin du Néolithique. Leur architecture pouvant être spécifique et leur nombre important sur certains territoires interrogent quant à leur développement et aux techniques mises en place dans leur élaboration. Plusieurs outils utilisés au cours des différentes phases de creusement de ces architectures souterraines sont ainsi connus. Ils sont présents dans divers contextes aussi bien en Sardaigne que dans le Sud de la France. Ces objets, découverts in situ, ne sont pas abandonnés dans ceux-ci mais bien déposés sous des formes particulières. Le mobilier de creusement est un outillage simple issu d’une chaîne opératoire de façonnage opportuniste. La présence de dépôts, dans les cavités artificielles, d’instruments utilisés pour les creuser n’est pas anodine et revêt sans doute différentes significations. Plusieurs interprétations ont été proposées dans la littérature et ce généralement en fonction des cas, allant du dépôt relatif aux défunts au dépôt collectif lié à l’architecture. Nous proposons donc une analyse comparative de cette pratique grâce à l’étude de plusieurs sites et types de données afin d’offrir une vision d’ensemble de ce phénomène et d’interroger la valeur symbolique de cet acte. Le dépôt d’outils dans les hypogées ayant été utilisés dans le creusement de ceux-ci interpelle en ce qui concerne leur phase de creusement et de mise en place, et quant à l’importance de la représentation symbolique au sein du groupe que la construction de tels monuments devait porter. Le creusement des hypogées nécessite un effort collectif notable, traduit sans doute par une organisation importante des groupes humains. Le dépôt des outils utilisés au cours de cette activité collective, lors de laquelle un grand nombre de personnes appartenant au groupe (voire des personnes venant de l’extérieur) participent, peut être associé à la volonté, le désir, de représenter cet aspect du collectif. Il scelle un moment majeur pour la communauté au cours duquel des efforts importants sont fournis par celle-ci.
Published: 2019

48. Time and age trends in smoking cessation in Europe

Author: Pesce, G, Marcon, A, Calciano, L, Perret, JL, Abramson, MJ, Bono, R, Bousquet, J, Fois, AG, Janson, C, Jarvis, D, Jogi, R, Leynaert, B, Nowak, D, Schlunssen, V, Urrutia-Landa, I, Verlato, G, Villani, S, Zuberbier, T, Minelli, C, Accordini, S, Boezen, M, Elger, B, Gleditsch, BA, Heijmans, B, Romieu, I, Thompson, J, Commission of the European Communities, Salvy-Córdoba, Nathalie, Physiopathologie et Epidémiologie des Maladies Respiratoires (PHERE (UMR_S_1152 / U1152)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), University Hospital of Verona, Università degli studi di Verona = University of Verona (UNIVR), University of Melbourne, Monash University [Melbourne], Università degli studi di Torino = University of Turin (UNITO), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Uppsala University Hospital, MRC Centre for Molecular Microbiology and Infection [Imperial College, London] (CMBI), Imperial College London, University of Tartu, Ludwig Maximilian University [Munich] (LMU), Aarhus University Hospital, Galdakao Hospital, Università degli Studi di Pavia = University of Pavia (UNIPV), Charité - UniversitätsMedizin = Charité - University Hospital [Berlin], Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP), University of Verona (UNIVR), University of Turin, University of Sassari, Università degli Studi di Pavia, Groningen Research Institute for Asthma and COPD (GRIAC), and Life Course Epidemiology (LCE)
Subjects: Male, Pulmonology, IMPACT, medicine.medical_treatment, Maternal Health, Tobacco Smoking / epidemiology, Social Sciences, RELAPSE, [SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract, Geographical Locations, Habits, INITIATION, 0302 clinical medicine, Elderly, Quality of life, Pregnancy, Smoking Habits, Medicine and Health Sciences, Medicine, Psychology, Public and Occupational Health, 030212 general & internal medicine, Young adult, PREDICTORS, 0303 health sciences, Multidisciplinary, Tobacco control, food and beverages, Obstetrics and Gynecology, Public Health, Global Health, Social Medicine and Epidemiology, Middle Aged, 3. Good health, PREVALENCE, Europe, Multidisciplinary Sciences, ALLERGIC RHINITIS, Age trends, Ageing Lungs in European Cohorts (ALEC) study, Europe, smoking cessation, time trends, Science & Technology - Other Topics, Female, Public Health, Europe / epidemiology, Research Article, Adult, medicine.medical_specialty, Tobacco Control, Smoking Cessation / statistics & numerical data, Adolescent, Substance-Related Disorders, General Science & Technology, Science, Health Promotion, Age trends, 03 medical and health sciences, Young Adult, Age Distribution, Sex Factors, Public Health, Tobacco Control, Tobacco Smoking, Smoking Cessation, Time Trends, Pregnancy, Mental Health and Psychiatry, MD Multidisciplinary, Tobacco Smoking, Humans, Risk factor, 030304 developmental biology, time trends, Behavior, Science & Technology, business.industry, Public health, Biology and Life Sciences, Smoking Related Disorders, Retrospective cohort study, ADULTS, Ageing Lungs in European Cohorts (ALEC) study, smoking cessation, Young Adults, Health Care, Retrospective studies, Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi, Health promotion, Age Groups, [SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie, People and Places, Quality of Life, Smoking cessation, Women's Health, [SDV.MHEP.PSR] Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract, ASTHMA, Population Groupings, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, business, Demography
Abstract: BackgroundSmoking is the main risk factor for most of the leading causes of death. Cessation is the single most important step that smokers can take to improve their health. With the aim of informing policy makers about decisions on future tobacco control strategies, we estimated time and age trends in smoking cessation in Europe between 1980 and 2010.MethodsData on the smoking history of 50,228 lifetime smokers from 17 European countries were obtained from six large population-based studies included in the Ageing Lungs in European Cohorts (ALEC) consortium. Smoking cessation rates were assessed retrospectively, and age trends were estimated for three decades (1980-1989, 1990-1999, 2000-2010). The analyses were stratified by sex and region (North, East, South, West Europe).ResultsOverall, 21,735 subjects (43.3%) quit smoking over a total time-at-risk of 803,031 years. Cessation rates increased between 1980 and 2010 in young adults (16-40 years), especially females, from all the regions, and in older adults (41-60 years) from North Europe, while they were stable in older adults from East, South and West Europe. In the 2000s, the cessation rates for men and women combined were highest in North Europe (49.9 per 1,000/ year) compared to the other regions (range: 26.5-32.7 per 1,000/ year). A sharp peak in rates was observed for women around the age of 30, possibly as a consequence of pregnancy-related smoking cessation. In most regions, subjects who started smoking before the age of 16 were less likely to quit than those who started later.ConclusionsOur findings suggest an increasing awareness on the detrimental effects of smoking across Europe. However, East, South and West European countries are lagging behind North Europe, suggesting the need to intensify tobacco control strategies in these regions. Additional efforts should be made to keep young adolescents away from taking up smoking, as early initiation could make quitting more challenging during later life.
Published: 2019

49. Did specialised courts affect the frequency of business bankruptcy petitions in Spain?

Author: Claudio Detotto, Marco Vannini, Laura Serra, Lieux, Identités, eSpaces, Activités (LISA), Université Pascal Paoli (UPP)-Centre National de la Recherche Scientifique (CNRS), Universitat Pompeu Fabra [Barcelona] (UPF), Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), and University of Sassari
Subjects: Economics and Econometrics, Entrepreneurship, 050208 finance, Insolvency, 05 social sciences, Commercial law, [SHS.ECO]Humanities and Social Sciences/Economics and Finance, Market economy, Order (exchange), Bankruptcy, 0502 economics and business, European integration, 050207 economics, Business and International Management, Distortion (economics), Law, ComputingMilieux_MISCELLANEOUS, Public finance
Abstract: Spanish small businesses rarely file for bankruptcy, and Spanish bankruptcy rates are abnormally small. The historical inadequacy of the Spanish insolvency system has led most enterprises to rely on the de facto alternative mortgage system and to overinvest in fixed tangible assets: a distortion that may trigger significant adverse effects, for instance on the enabling environment of novel entrepreneurship. The reform of the bankruptcy law that took place in Spain some 10 years in order to modernise the insolvency system involved, as a main novelty, the establishment of specialised commercial courts (Juzgados de lo Mercantil). Since the net benefits of specialised judicial functions are in principle ambiguous, we study empirically whether these new bodies had any impact, over and above the economic crisis, on the use of the bankruptcy system. Exploiting the staggered timing of the new courts geography, we estimate an endogenous treatment model with a binary policy variable which allows to measure the effect of the reform on bankruptcy rates. The results support the view that the new bankruptcy law took the right path, but the size of the estimated parameters call for further policy efforts in that direction.
Published: 2019

50. COMPARATIVE EFFICIENCY OF AGRICULTURAL COOPERATIVES AND CONVENTIONAL FIRMS IN A SAMPLE OF QUASI-TWIN COMPANIES

Author: Brandano, Maria Giovanna, Detotto, Claudio, Vannini, Marco, University of Sassari, Lieux, Identités, eSpaces, Activités (LISA), Centre National de la Recherche Scientifique (CNRS)-Université Pascal Paoli (UPP), Université Pascal Paoli (UPP)-Centre National de la Recherche Scientifique (CNRS), and Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS)
Subjects: [SHS.ECO]Humanities and Social Sciences/Economics and Finance, ComputingMilieux_MISCELLANEOUS
Abstract: International audience
Published: 2019

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