Author: "Univ Santiago Compostela" - Searchworks@Jio Institute Digital Library Search Results

6 results on '"Univ Santiago Compostela"'

1. HYDROALCOHOLIC SYSTEM FOR NAIL TREATMENT

Author: UNIV SANTIAGO COMPOSTELA

2. Integrating digital pathology with transcriptomic and epigenomic tools for predicting metastatic uterine tumor aggressiveness

Author: Giorgia Sonzini, Sofia Granados-Aparici, Sabina Sanegre, Angel Diaz-Lagares, Juan Diaz-Martin, Carlos de Andrea, Núria Eritja, Aida Bao-Caamano, Nicolás Costa-Fraga, David García-Ros, Carmen Salguero-Aranda, Ben Davidson, Rafael López-López, Ignacio Melero, Samuel Navarro, Santiago Ramon y Cajal, Enrique de Alava, Xavier Matias-Guiu, Rosa Noguera, Instituto de Salud Carlos III, European Commission, Centro de Investigación Biomédica en Red Cáncer (España), Asociación Española Contra el Cáncer, Xunta de Galicia, [Sonzini, Giorgia] Univ Valencia INCLIVA, Med Sch, Dept Pathol, Valencia, Spain, [Granados-Aparici, Sofia] Univ Valencia INCLIVA, Med Sch, Dept Pathol, Valencia, Spain, [Sanegre, Sabina] Univ Valencia INCLIVA, Med Sch, Dept Pathol, Valencia, Spain, [Navarro, Samuel] Univ Valencia INCLIVA, Med Sch, Dept Pathol, Valencia, Spain, [Noguera, Rosa] Univ Valencia INCLIVA, Med Sch, Dept Pathol, Valencia, Spain, [Sanegre, Sabina] Canc CIBER CIBERONC, Madrid, Spain, [Diaz-Lagares, Angel] Canc CIBER CIBERONC, Madrid, Spain, [Diaz-Martin, Juan] Canc CIBER CIBERONC, Madrid, Spain, [de Andrea, Carlos] Canc CIBER CIBERONC, Madrid, Spain, [Eritja, Nuria] Canc CIBER CIBERONC, Madrid, Spain, [Salguero-Aranda, Carmen] Canc CIBER CIBERONC, Madrid, Spain, [Lopez-Lopez, Rafael] Canc CIBER CIBERONC, Madrid, Spain, [Melero, Ignacio] Canc CIBER CIBERONC, Madrid, Spain, [Navarro, Samuel] Canc CIBER CIBERONC, Madrid, Spain, [Ramon y Cajal, Santiago] Canc CIBER CIBERONC, Madrid, Spain, [de Alava, Enrique] Canc CIBER CIBERONC, Madrid, Spain, [Matias-Guiu, Xavier] Canc CIBER CIBERONC, Madrid, Spain, [Noguera, Rosa] Canc CIBER CIBERONC, Madrid, Spain, [Diaz-Lagares, Angel] Univ Clin Hosp Santiago CHUS SERGAS, Hlth Res Inst Santiago IDIS, Epigen Unit, Canc Epigen Translat Med Oncol Grp Oncomet, Santiago De Compostela, Spain, [Bao-Caamano, Aida] Univ Clin Hosp Santiago CHUS SERGAS, Hlth Res Inst Santiago IDIS, Epigen Unit, Canc Epigen Translat Med Oncol Grp Oncomet, Santiago De Compostela, Spain, [Costa-Fraga, Nicolas] Univ Clin Hosp Santiago CHUS SERGAS, Hlth Res Inst Santiago IDIS, Epigen Unit, Canc Epigen Translat Med Oncol Grp Oncomet, Santiago De Compostela, Spain, [Diaz-Martin, Juan] Univ Seville, Virgen Rocio Univ Hosp, Inst BioMed Sevilla, CSIC, Seville, Spain, [Salguero-Aranda, Carmen] Univ Seville, Virgen Rocio Univ Hosp, Inst BioMed Sevilla, CSIC, Seville, Spain, [de Alava, Enrique] Univ Seville, Virgen Rocio Univ Hosp, Inst BioMed Sevilla, CSIC, Seville, Spain, [de Andrea, Carlos] Univ Navarra, Clin Univ Navarra, Pamplona, Spain, [Garcia-Ros, David] Univ Navarra, Clin Univ Navarra, Pamplona, Spain, [Melero, Ignacio] Univ Navarra, Clin Univ Navarra, Pamplona, Spain, [Eritja, Nuria] Univ Barcelona, Univ Lleida, Inst Recerca Biomed LLeida IRBLLEIDA,Dept Pathol, Inst Invest Biomed Bellvitge IDIBELL,Hosp U Arnau, Barcelona, Spain, [Matias-Guiu, Xavier] Univ Barcelona, Univ Lleida, Inst Recerca Biomed LLeida IRBLLEIDA,Dept Pathol, Inst Invest Biomed Bellvitge IDIBELL,Hosp U Arnau, Barcelona, Spain, [Eritja, Nuria] Univ Barcelona, Bellvitge Hosp, Univ Lleida, Barcelona, Spain, [Matias-Guiu, Xavier] Univ Barcelona, Bellvitge Hosp, Univ Lleida, Barcelona, Spain, [Bao-Caamano, Aida] Univ Santiago Compostela USC, Santiago De Compostela, Spain, [Costa-Fraga, Nicolas] Univ Santiago Compostela USC, Santiago De Compostela, Spain, [Davidson, Ben] Univ Oslo, Inst Clin Med, Fac Med, Oslo, Norway, [Davidson, Ben] Univ Oslo, Norwegian Radium Hosp, Dept Pathol, Oslo, Norway, [Lopez-Lopez, Rafael] Hlth Res Inst Santiago IDIS, Translat Med Oncol Grp Oncomet, Roche Chus Joint Unit, Santiago De Compostela, Spain, and [Ramon y Cajal, Santiago] Univ Autonoma Barcelona, Vall Hebron Univ Hosp, Dept Pathol, Barcelona, Spain
Subjects: Cell Biology, Epigenètica, Defines, Multiplex immunofluorescence, Metastasis, Methylomics, Lung metastasis, Càncer d'úter, Invasive tumor front, Metàstasi, Uterine adenocarcinoma, Uterine leiomyosarcoma, Uterine cancer, Digital pathology, Epigenetics, Collagen, Transcriptomics, Developmental Biology, Cancer
Abstract: The incidence of new cancer cases is expected to increase significantly in the future, posing a worldwide problem. In this regard, precision oncology and its diagnostic tools are essential for developing personalized cancer treatments. Digital pathology (DP) is a particularly key strategy to study the interactions of tumor cells and the tumor microenvironment (TME), which play a crucial role in tumor initiation, progression and metastasis. The purpose of this study was to integrate data on the digital patterns of reticulin fiber scaffolding and the immune cell infiltrate, transcriptomic and epigenetic profiles in aggressive uterine adenocarcinoma (uADC), uterine leiomyosarcoma (uLMS) and their respective lung metastases, with the aim of obtaining key TME biomarkers that can help improve metastatic prediction and shed light on potential therapeutic targets. Automatized algorithms were used to analyze reticulin fiber architecture and immune infiltration in colocalized regions of interest (ROIs) of 133 invasive tumor front (ITF), 89 tumor niches and 70 target tissues in a total of six paired samples of uADC and nine of uLMS. Microdissected tissue from the ITF was employed for transcriptomic and epigenetic studies in primary and metastatic tumors. Reticulin fiber scaffolding was characterized by a large and loose reticular fiber network in uADC, while dense bundles were found in uLMS. Notably, more similarities between reticulin fibers were observed in paired uLMS then paired uADCs. Transcriptomic and multiplex immunofluorescence-based immune profiling showed a higher abundance of T and B cells in primary tumor and in metastatic uADC than uLMS. Moreover, the epigenetic signature of paired samples in uADCs showed more differences than paired samples in uLMS. Some epigenetic variation was also found between the ITF of metastatic uADC and uLMS. Altogether, our data suggest a correlation between morphological and molecular changes at the ITF and the degree of aggressiveness. The use of DP tools for characterizing reticulin scaffolding and immune cell infiltration at the ITF in paired samples together with information provided by omics analyses in a large cohort will hopefully help validate novel biomarkers of tumor aggressiveness, develop new drugs and improve patient quality of life in a much more efficient way., This research was supported by grants from the ISCIII and ERDF (PI17/01558), by the CIBERONC (contracts CB16/12/00484, CB16/12/0328, CB16/12/00363, CB16/12/00364, CB16/12/00481, and CB16/12/00231) and Grupos Coordinados Estables from the Asociación Española Contra el Cáncer (AECC). AB-C was funded by a predoctoral contract PFIS from ISCIII (FI19/00240) co-funded by “Fondo Social Europeo” (FSE). NC-F was funded by a predoctoral contract from “Xunta de Galicia” (IN606A-2020/004). AD-L was funded by a “Juan Rodés” contract from the ISCIII (JR17/00016).
Published: 2022

3. Obesity- and gender-dependent role of endogenous somatostatin and cortistatin in the regulation of endocrine and metabolic homeostasis in mice

Author: Manuel D. Gahete, Jose Cordoba-Chacon, Ana I. Pozo-Salas, Justo P. Castaño, Luis de Lecea, Begoña Porteiro, Raúl M. Luque, Rubén Nogueiras, [Luque, Raul M.] Maimonides Inst Biomed Res Cordoba IMIBIC, Cordoba, Spain, [Cordoba-Chacon, Jose] Maimonides Inst Biomed Res Cordoba IMIBIC, Cordoba, Spain, [Pozo-Salas, Ana I.] Maimonides Inst Biomed Res Cordoba IMIBIC, Cordoba, Spain, [Gahete, Manuel D.] Maimonides Inst Biomed Res Cordoba IMIBIC, Cordoba, Spain, [Castano, Justo P.] Maimonides Inst Biomed Res Cordoba IMIBIC, Cordoba, Spain, [Luque, Raul M.] Univ Cordoba, Dept Cell Biol Physiol & Immunol, Cordoba, Spain, [Cordoba-Chacon, Jose] Univ Cordoba, Dept Cell Biol Physiol & Immunol, Cordoba, Spain, [Pozo-Salas, Ana I.] Univ Cordoba, Dept Cell Biol Physiol & Immunol, Cordoba, Spain, [Gahete, Manuel D.] Univ Cordoba, Dept Cell Biol Physiol & Immunol, Cordoba, Spain, [Castano, Justo P.] Univ Cordoba, Dept Cell Biol Physiol & Immunol, Cordoba, Spain, [Luque, Raul M.] HURS, Cordoba, Spain, [Cordoba-Chacon, Jose] HURS, Cordoba, Spain, [Pozo-Salas, Ana I.] HURS, Cordoba, Spain, [Gahete, Manuel D.] HURS, Cordoba, Spain, [Castano, Justo P.] HURS, Cordoba, Spain, [Luque, Raul M.] CIBER Fisiopatol Obesidad & Nutr CIBERobn, Cordoba, Spain, [Cordoba-Chacon, Jose] CIBER Fisiopatol Obesidad & Nutr CIBERobn, Cordoba, Spain, [Pozo-Salas, Ana I.] CIBER Fisiopatol Obesidad & Nutr CIBERobn, Cordoba, Spain, [Porteiro, Begona] CIBER Fisiopatol Obesidad & Nutr CIBERobn, Cordoba, Spain, [Nogueiras, Ruben] CIBER Fisiopatol Obesidad & Nutr CIBERobn, Cordoba, Spain, [Gahete, Manuel D.] CIBER Fisiopatol Obesidad & Nutr CIBERobn, Cordoba, Spain, [Castano, Justo P.] CIBER Fisiopatol Obesidad & Nutr CIBERobn, Cordoba, Spain, [Luque, Raul M.] Campus Excelencia Internac Agroalimentario ceiA3, Cordoba, Spain, [Cordoba-Chacon, Jose] Campus Excelencia Internac Agroalimentario ceiA3, Cordoba, Spain, [Pozo-Salas, Ana I.] Campus Excelencia Internac Agroalimentario ceiA3, Cordoba, Spain, [Gahete, Manuel D.] Campus Excelencia Internac Agroalimentario ceiA3, Cordoba, Spain, [Castano, Justo P.] Campus Excelencia Internac Agroalimentario ceiA3, Cordoba, Spain, [Cordoba-Chacon, Jose] Univ Illinois, Dept Med, Sect Endocrinol Diabet & Metab, Chicago, IL 60607 USA, [Cordoba-Chacon, Jose] Jesse Brown Veteran Affairs Med Ctr, Div Res & Dev, Chicago, IL 60612 USA, [Porteiro, Begona] Univ Santiago Compostela, Inst Invest Sanitaria, CIMUS, Dept Physiol, Santiago De Compostela, Spain, [Nogueiras, Ruben] Univ Santiago Compostela, Inst Invest Sanitaria, CIMUS, Dept Physiol, Santiago De Compostela, Spain, [de Lecea, Luis] Stanford Univ, Sch Med, Dept Psychiat & Behav Sci, Palo Alto, CA 94304 USA, Junta de Andalucia, ISCIII-FIS - European Regional Development Fund/European Social Fund 'Investing in your future', MINECO, 'Miguel Servet' Program, CIBERobn, Ayuda Merck Serono, and Universidade de Santiago de Compostela. Centro de Investigación en Medicina Molecular e Enfermidades Crónicas
Subjects: 0301 basic medicine, System, Male, medicine.medical_specialty, Pituitary gland, endocrine system, Glucose-homeostasis, medicine.medical_treatment, Endogeny, Expression, Biology, Article, Cortistatin (neuropeptide), 03 medical and health sciences, Mice, Internal medicine, Receptors, polycyclic compounds, medicine, Gh output, Endocrine system, Animals, Homeostasis, Obesity, Secretion, Mice, Knockout, Sex Characteristics, Multidisciplinary, Insulin, Neuropeptides, Insulin sensitivity, Dietary Fats, Prolactin, Ghrelin, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, Somatostatin, Endocrinology, Pituitary Gland, Igf-i, Female, hormones, hormone substitutes, and hormone antagonists, Growth-hormone-axis
Abstract: Somatostatin (SST) and cortistatin (CORT) regulate numerous endocrine secretions and their absence [knockout (KO)-models] causes important endocrine-metabolic alterations, including pituitary dysregulations. We have demonstrated that the metabolic phenotype of single or combined SST/CORT KO-models is not drastically altered under normal conditions. However, the biological actions of SST/CORT are conditioned by the metabolic-status (e.g. obesity). Therefore, we used male/female SST- and CORT-KO mice fed low-fat (LF) or high-fat (HF) diet to explore the interplay between SST/CORT and obesity in the control of relevant pituitary-axes and whole-body metabolism. Our results showed that the SST/CORT role in the control of GH/prolactin secretions is maintained under LF- and HF-diet conditions as SST-KOs presented higher GH/prolactin-levels, while CORT-KOs displayed higher GH- and lower prolactin-levels than controls under both diets. Moreover, the impact of lack of SST/CORT on the metabolic-function was gender- and diet-dependent. Particularly, SST-KOs were more sensitive to HF-diet, exhibiting altered growth and body-composition (fat/lean percentage) and impaired glucose/insulin-metabolism, especially in males. Conversely, only males CORT-KO under LF-diet conditions exhibited significant alterations, displaying higher glucose-levels and insulin-resistance. Altogether, these data demonstrate a tight interplay between SST/CORT-axis and the metabolic status in the control of endocrine/metabolic functions and unveil a clear dissociation of SST/CORT roles This work was supported by the following grants: Junta de Andalucía (CTS-1406, BIO-0139), ISCIII-FIS [PI13/00651 and PIE14/00005 (co-funded by European Regional Development Fund/European Social Fund “Investing in your future”)], MINECO (BFU2013–43282-R), “Miguel Servet” Program, CIBERobn and Ayuda Merck Serono 2013 SI
Published: 2016

4. Levosimendan beyond inotropy and acute heart failure: Evidence of pleiotropic effects on the heart and other organs: An expert panel position paper

Author: Farmakis, Dimitrios, Alvarez, Julian, Ben Gal, Tuvia, Brito, Dulce, Fedele, Francesco, Fonseca, Candida, Gordon, Anthony C., Gotsman, Israel, Grossini, Elena, Guarracino, Fabio, Harjola, Veli-Pekka, Hellman, Yaron, Heunks, Leo, Ivancan, Visnja, Karavidas, Apostolos, Kivikko, Matti, Lomivorotov, Vladimir, Longrois, Dan, Masip, Josep, Metra, Marco, Morelli, Andrea, Nikolaou, Maria, Papp, Zoltan, Parkhomenko, Alexander, Poelzl, Gerhard, Pollesello, Piero, Ravn, Hanne Berg, Rex, Steffen, Riha, Hynek, Ricksten, Sven-Erik, Schwinger, Robert H. G., Vrtovec, Bojan, Yilmaz, M. Birhan, Zielinska, Marzenna, Parissis, John, Clinicum, Anestesiologian yksikkö, Department of Diagnostics and Therapeutics, [Farmakis, Dimitrios -- Parissis, John] Univ Athens, Univ Athens, Dept Cardiol, Heart Failure Unit,Univ Attikon, Athens, Greece -- [Alvarez, Julian] Univ Santiago Compostela, Dept Anesthesia, Santiago De Compostela, Spain -- [Alvarez, Julian] Univ Santiago Compostela, Surg ICU, Santiago De Compostela, Spain -- [Ben Gal, Tuvia] Rabin Med Ctr, Cardiol Clin, Petah Tiqwa, Israel -- [Brito, Dulce] Hosp Santa Maria, Dept Cardiol, Ctr Hosp Lisboa Norte, Lisbon, Portugal -- [Fedele, Francesco] Sapienza Univ Rome, Dept Cardiovasc Resp Nephrol Anesthesiol & Geriat, Rome, Italy -- [Fonseca, Candida] Univ Nova Lisboa, Heart Failure Unit, Dept Internal Med,NOVA Med Sch,Fac Ciencias Med, Hosp Sao Francico Xavier,Ctr Hosp Lisbo Ocidental, Lisbon, Portugal -- [Gordon, Anthony C.] Imperial Coll London, Sect Anaesthet Pain Med & Intens Care, London, England -- [Gotsman, Israel] Hadassah Univ Hosp Jerusalem, Inst Heart, Cardiol Clin, Jerusalem, Israel -- [Grossini, Elena] Univ East Piedmont, Physiol Lab, Novara, Italy -- [Guarracino, Fabio] Azienda Osped Univ Pisana, Dept Anaesthesia & Crit Care Med Cardiothorac Ana, Pisa, Italy -- [Harjola, Veli-Pekka] Univ Helsinki, Helsinki Univ Hosp, Emergency Med, Helsinki, Finland -- [Hellman, Yaron] Carmel Hosp, Heart Failure Serv, Haifa, Israel -- [Heunks, Leo] Radboud Univ Nijmegen, Med Ctr, Dept Intens Care, Nijmegen, Netherlands -- [Ivancan, Visnja] Univ Hosp Ctr, Emergency Cardiol Dept, Zagreb, Croatia -- [Karavidas, Apostolos] G Gennimatas Gen Hosp, Dept Cardiol, Athens, Greece -- [Kivikko, Matti -- Pollesello, Piero] Orion Pharma, Crit Care Proprietary Prod, Espoo, Finland -- [Lomivorotov, Vladimir] State Res Inst Circulat Pathol, Dept Anesthesiol & Intens Care, Novosibirsk, Russia -- [Longrois, Dan] Univ Paris Diderot, Hop Uiversitaires Paris Nord Val Seine, Hop Bichat Claude Bernard, Dept Anesthesie Reanimat Chirurg, Paris, France -- [Masip, Josep] Hosp St Joan Despi Moises Broggi, Intens Care Unit, Barcelona, Spain -- [Metra, Marco] Univ & Civil Hosp, Cardiol Clin, Brescia, Italy -- [Morelli, Andrea] Univ Roma La Sapienza, Dept Anesthesiol & Intens Care, Policlin Umberto 1, Rome, Italy -- [Nikolaou, Maria] Sismanoglio & Amalia Fleming Gen Hosp, Dept Cardiol, Athens, Greece -- [Papp, Zoltan] Univ Debrecen, Fac Med, Dept Cardiol, Div Clin Physiol, Debrecen, Hungary -- [Parkhomenko, Alexander] Inst Cardiol, Dept Anesthesiol, Kiev, Ukraine -- [Parkhomenko, Alexander] Inst Cardiol, Intens Care Unit Cardiac Surg Patients, Kiev, Ukraine -- [Poelzl, Gerhard] Univ Klin Innsbruck, Innere Med 3, Innsbruck, Austria -- [Ravn, Hanne Berg] Rigshosp, Ctr Heart, Dept Cardiothorac Anaesthesia, Copenhagen, Denmark -- [Rex, Steffen] Univ Leuven, Dept Cardiovasc Sci, Leuven, Belgium -- [Riha, Hynek] Inst Clin & Expt Med, Dept Anaesthesiol & Intens Care Med, Cardiothorac Anaesthesiol & Intens Care, Prague, Czech Republic -- [Ricksten, Sven-Erik] Univ Gothenburg, Sahlgrenska Univ Hosp, Inst Clin Sci, Dept Anesthesiol & Intens Care Med, Gothenburg, Sweden -- [Schwinger, Robert H. G.] Klinikum Weiden, Med Klin 2, Weiden, Germany -- [Vrtovec, Bojan] Univ Clin Ctr Ljubljana, Dept Cardiol, Ljubljana, Slovenia -- [Yilmaz, M. Birhan] Cumhuriyet Univ, Dept Cardiol, Sivas, Turkey -- [Zielinska, Marzenna] Med Univ Lodz, Dept Intens Cardiac Therapy, Lodz, Poland, Brito, Dulce Alves -- 0000-0003-1278-1847, Lomivorotov, Vladimir -- 0000-0001-8591-6461, Pollesello, Piero -- 0000-0001-6994-768X, YILMAZ, Mehmet Birhan -- 0000-0002-8169-8628, Zielinska, Marzenna -- 0000-0002-0118-8610, Gordon, Anthony -- 0000-0002-0419-547X, YILMAZ, MEHMET BIRHAN -- 0000-0002-8169-8628, Alvarez, Julian -- 0000-0002-2518-0891, MORELLI, ANDREA -- 0000-0001-6065-1006, Riha, Hynek -- 0000-0002-9861-7361, Gotsman, Israel -- 0000-0001-9608-2298, and Rex, Steffen -- 0000-0002-3536-9321
Subjects: Levosimendan, 3121 General medicine, internal medicine and other clinical medicine, Inotropes, education, Heart failure, Cardioprotection, Cardiogenic shock, Organ protection
Abstract: WOS: 000384698300056, PubMed ID: 27498374, Levosimendan is a positive inotrope with vasodilating properties (inodilator) indicated for decompensated heart failure (HF) patients with low cardiac output. Accumulated evidence supports several pleiotropic effects of levosimendan beyond inotropy, the heart and decompensated HF. Those effects are not readily explained by cardiac function enhancement and seem to be related to additional properties of the drug such as anti-inflammatory, anti-oxidative and anti-apoptotic ones. Mechanistic and proof-of-concept studies are still required to clarify the underlying mechanisms involved, while properly designed clinical trials are warranted to translate preclinical or early-phase clinical data into more robust clinical evidence. The present position paper, derived by a panel of 35 experts in the field of cardiology, cardiac anesthesiology, intensive care medicine, cardiac physiology, and cardiovascular pharmacology from 22 European countries, compiles the existing evidence on the pleiotropic effects of levosimendan, identifies potential novel areas of clinical application and defines the corresponding gaps in evidence and the required research efforts to address those gaps. (C) 2016 The Authors. Published by Elsevier Ireland Ltd., Orion Pharma Oyj/Abp (Finland); Medis d.o.o. (Croatia); Biomed JR Ltd. (Israel); TENAX Therapeutics Ltd. (U.S.A.), This project did not receive any financial support, apart from unrestricted grants by Orion Pharma Oyj/Abp (Finland), Medis d.o.o. (Croatia), Biomed JR Ltd. (Israel), and TENAX Therapeutics Ltd. (U.S.A.) that covered the logistic expenses related to the consensus meeting in Athens on Feb. 26-27, 2016. The attendees did not receive any honoraria. P.P. and M.K. are employees of Orion Pharma.
Published: 2016

5. Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: A pooled analysis of 1018 population-based measurement studies with 88.6 million participants

Author: Yiallouros, Panayiotis K., Escobedo-de la Peña, Jorge, Zhou, Bin, Bentham, James, Di Cesare, Mariachiara, Bixby, Honor, Danaei, Goodarz, Hajifathalian, Kaveh, Taddei, Cristina, Carrillo-Larco, Rodrigo M., Djalalinia, Shirin, Khatibzadeh, Shahab, Lugero, Charles, Peykari, Niloofar, Zhang, Wan Zhu, Bennett, James, Bilano, Ver, Stevens, Gretchen A., Cowan, Melanie J., Riley, Leanne M., Chen, Zhengming, Hambleton, Ian R., Jackson, Rod T., Kengne, Andre Pascal, Khang, Young-Ho, Laxmaiah, Avula, Liu, Jing, Malekzadeh, Reza, Neuhauser, Hannelore K., Sorić, Maroje, Starc, Gregor, Sundström, Johan, Woodward, Mark, Ezzati, Majid, Abarca-Gómez, Leandra, Abdeen, Ziad A., Abu-Rmeileh, Niveen M., Acosta-Cazares, Benjamin, Adams, Robert J., Aekplakorn, Wichai, Afsana, Kaosar, Aguilar-Salinas, Carlos A., Agyemang, Charles, Ahmad, Noor Ani, Ahmadvand, Alireza, Ahrens, Wolfgang, Ajlouni, Kamel, Akhtaeva, Nazgul, Al-Raddadi, Rajaa, Ali, Mohamed M., Ali, Osman, Alkerwi, Ala'a, Aly, Eman, Amarapurkar, Deepak N., Amouyel, Philippe, Amuzu, Antoinette, Andersen, Lars Bo, Anderssen, Sigmund A., Ängquist, Lars H., Anjana, Ranjit Mohan, Ansong, Daniel, Aounallah-Skhiri, Hajer, Araújo, Joana, Ariansen, Inger, Aris, Tahir, Arlappa, Nimmathota, Arveiler, Dominique, Aryal, Krishna K., Aspelund, Thor, Assah, Felix K., Assunção, Maria Cecília F., Avdicová, Mária, Azevedo, Ana, Azizi, Fereidoun, Babu, Bontha V., Bahijri, Suhad, Balakrishna, Nagalla, Bamoshmoosh, Mohamed, Banach, Maciej, Bandosz, Piotr, Banegas, José R., Barbagallo, Carlo M., Barceló, Alberto, Barkat, Amina, Barros, Aluisio J. D., Barros, Mauro V., Bata, Iqbal, Batieha, Anwar M., Batyrbek, Assembekov, Baur, Louise A., Beaglehole, Robert, Romdhane, Habiba Ben, Benet, Mikhail, Benson, Lowell S., Bernabe-Ortiz, Antonio, Bernotiene, Gailute, Bettiol, Heloisa, Bhagyalaxmi, Aroor, Bharadwaj, Sumit, Bhargava, Santosh K., Bi, Yufang, Bikbov, Mukharram, Bista, Bihungum, Bjerregaard, Peter, Bjertness, Espen, Bjertness, Marius B., Björkelund, Cecilia, Blokstra, Anneke, Bo, Simona, Bobak, Martin, Boeing, Heiner, Boggia, Jose G., Boissonnet, Carlos P., Bongard, Vanina, Borchini, Rossana, Bovet, Pascal, Braeckman, Lutgart, Brajkovich, Imperia, Branca, Francesco, Breckenkamp, Juergen, Brenner, Hermann, Brewster, Lizzy M., Bruno, Graziella, Bueno-de-Mesquita, H. B(as), Bugge, Anna, Burns, Con, Bursztyn, Michael, de León, Antonio Cabrera, Cacciottolo, Joseph, Cai, Hui, Cameron, Christine, Can, Günay, Cândido, Ana Paula C., Capuano, Vincenzo, Cardoso, Viviane C., Carlsson, Axel C., Carvalho, Maria J., Casanueva, Felipe F., Casas, Juan-Pablo, Caserta, Carmelo A., Chamukuttan, Snehalatha, Chan, Angelique W., Chan, Queenie, Chaturvedi, Himanshu K., Chaturvedi, Nishi, Chen, Chien-Jen, Chen, Fangfang, Chen, Huashuai, Chen, Shuohua, Cheng, Ching-Yu, Dekkaki, Imane Cherkaoui, Chetrit, Angela, Chiolero, Arnaud, Chiou, Shu-Ti, Chirita-Emandi, Adela, Chirlaque, María-Dolores, Cho, Belong, Cho, Yumi, Christofaro, Diego G., Chudek, Jerzy, Cifkova, Renata, Cinteza, Eliza, Claessens, Frank, Clays, Els, Concin, Hans, Cooper, Cyrus, Cooper, Rachel, Coppinger, Tara C., Costanzo, Simona, Cottel, Dominique, Cowell, Chris, Craig, Cora L., Crujeiras, Ana B., Cruz, Juan J., D'Arrigo, Graziella, d'Orsi, Eleonora, Dallongeville, Jean, Damasceno, Albertino, Dankner, Rachel, Dantoft, Thomas M., Dauchet, Luc, Davletov, Kairat, De Backer, Guy, De Bacquer, Dirk, de Gaetano, Giovanni, De Henauw, Stefaan, de Oliveira, Paula Duarte, De Smedt, Delphine, Deepa, Mohan, Dehghan, Abbas, Delisle, Hélène, Deschamps, Valérie, Dhana, Klodian, Di Castelnuovo, Augusto F., Dias-da-Costa, Juvenal Soares, Diaz, Alejandro, Dickerson, Ty T., Do, Ha T. P., Donfrancesco, Chiara, Donoso, Silvana P., Döring, Angela, Dorobantu, Maria, Doua, Kouamelan, Drygas, Wojciech, Dulskiene, Virginija, Džakula, Aleksandar, Dzerve, Vilnis, Dziankowska-Zaborszczyk, Elzbieta, Eggertsen, Robert, Ekelund, Ulf, El Ati, Jalila, Elliott, Paul, Elosua, Roberto, Erasmus, Rajiv T., Erem, Cihangir, Eriksen, Louise, Eriksson, Johan G., Evans, Alun, Faeh, David, Fall, Caroline H., Farzadfar, Farshad, Felix-Redondo, Francisco J., Ferguson, Trevor S., Fernandes, Romulo A., Fernández-Bergés, Daniel, Ferrante, Daniel, Ferrari, Marika, Ferreccio, Catterina, Ferrieres, Jean, Finn, Joseph D., Fischer, Krista, Föger, Bernhard, Foo, Leng Huat, Forslund, Ann-Sofie, Forsner, Maria, Fouad, Heba M., Francis, Damian K., do Carmo Franco, Maria, Franco, Oscar H., Frontera, Guillermo, Fuchs, Flavio D., Fuchs, Sandra C., Fujita, Yuki, Furusawa, Takuro, Gaciong, Zbigniew, Galvano, Fabio, Garcia-de-la-Hera, Manoli, Gareta, Dickman, Garnett, Sarah P., Gaspoz, Jean-Michel, Gasull, Magda, Gates, Louise, Geleijnse, Johanna M., Ghasemian, Anoosheh, Ghimire, Anup, Giampaoli, Simona, Gianfagna, Francesco, Gill, Tiffany K., Giovannelli, Jonathan, Goldsmith, Rebecca A., Gonçalves, Helen, Gonzalez-Gross, Marcela, González-Rivas, Juan P., Gorbea, Mariano Bonet, Gottrand, Frederic, Graff-Iversen, Sidsel, Grafnetter, Dušan, Grajda, Aneta, Grammatikopoulou, Maria G., Gregor, Ronald D., Grodzicki, Tomasz, Grøntved, Anders, Grosso, Giuseppe, Gruden, Gabriella, Grujic, Vera, Gu, Dongfeng, Guan, Ong Peng, Gudmundsson, Elias F., Gudnason, Vilmundur, Guerrero, Ramiro, Guessous, Idris, Guimaraes, Andre L., Gulliford, Martin C., Gunnlaugsdottir, Johanna, Gunter, Marc, Gupta, Prakash C., Gupta, Rajeev, Gureje, Oye, Gurzkowska, Beata, Gutierrez, Laura, Gutzwiller, Felix, Hadaegh, Farzad, Halkjær, Jytte, Hardy, Rebecca, Hari Kumar, Rachakulla, Hata, Jun, Hayes, Alison J., He, Jiang, He, Yuna, Elisabeth, Marleen, Henriques, Ana, Cadena, Leticia Hernandez, Herrala, Sauli, Heshmat, Ramin, Hihtaniemi, Ilpo Tapani, Ho, Sai Yin, Ho, Suzanne C., Hobbs, Michael, Hofman, Albert, Dinc, Gonul Horasan, Horimoto, Andrea R. V. R., Hormiga, Claudia M., Horta, Bernardo L., Houti, Leila, Howitt, Christina, Htay, Thein Thein, Htet, Aung Soe, Than Htike, Maung Maung, Hu, Yonghua, Huerta, José María, Huisman, Martijn, Husseini, Abdullatif S., Huybrechts, Inge, Hwalla, Nahla, Iacoviello, Licia, Iannone, Anna G., Ibrahim, Mohsen M., Wong, Norazizah Ibrahim, Ikeda, Nayu, Ikram, M. Arfan, Irazola, Vilma E., Islam, Muhammad, al-Safi Ismail, Aziz, Ivkovic, Vanja, Iwasaki, Masanori, Jacobs, Jeremy M., Jaddou, Hashem, Jafar, Tazeen, Jamrozik, Konrad, Janszky, Imre, Jasienska, Grazyna, Jelaković, Ana, Jelaković, Bojan, Jennings, Garry, Jeong, Seung-lyeal, Jiang, Chao Qiang, Joffres, Michel, Johansson, Mattias, Jokelainen, Jari J., Jonas, Jost B., Jørgensen, Torben, Joshi, Pradeep, Jóźwiak, Jacek, Juolevi, Anne, Jurak, Gregor, Jureša, Vesna, Kaaks, Rudolf, Kafatos, Anthony, Kajantie, Eero O., Kalter-Leibovici, Ofra, Kamaruddin, Nor Azmi, Karki, Khem B., Kasaeian, Amir, Katz, Joanne, Kauhanen, Jussi, Kaur, Prabhdeep, Kavousi, Maryam, Kazakbaeva, Gyulli, Keil, Ulrich, Boker, Lital Keinan, Keinänen-Kiukaanniemi, Sirkka, Kelishadi, Roya, Kemper, Han C. G., Kengne, Andre P., Kerimkulova, Alina, Kersting, Mathilde, Key, Timothy, Khader, Yousef Saleh, Khalili, Davood, Khateeb, Mohammad, Khaw, Kay-Tee, Kiechl-Kohlendorfer, Ursula, Kiechl, Stefan, Killewo, Japhet, Kim, Jeongseon, Kim, Yeon-Yong, Klumbiene, Jurate, Knoflach, Michael, Kolle, Elin, Kolsteren, Patrick, Korrovits, Paul, Koskinen, Seppo, Kouda, Katsuyasu, Kowlessur, Sudhir, Koziel, Slawomir, Kriemler, Susi, Kristensen, Peter Lund, Krokstad, Steinar, Kromhout, Daan, Kruger, Herculina S., Kubinova, Ruzena, Kuciene, Renata, Kuh, Diana, Kujala, Urho M., Kulaga, Zbigniew, Krishna Kumar, R., Kurjata, Pawel, Kusuma, Yadlapalli S., Kuulasmaa, Kari, Kyobutungi, Catherine, Laatikainen, Tiina, Lachat, Carl, Lam, Tai Hing, Landrove, Orlando, Lanska, Vera, Lappas, Georg, Larijani, Bagher, Laugsand, Lars E., Le Nguyen Bao, Khanh, Le, Tuyen D., Leclercq, Catherine, Lee, Jeannette, Lee, Jeonghee, Lehtimäki, Terho, León-Muñoz, Luz M., Levitt, Naomi S., Li, Yanping, Lilly, Christa L., Lim, Wei-Yen, Lima-Costa, M. Fernanda, Lin, Hsien-Ho, Lin, Xu, Lind, Lars, Linneberg, Allan, Lissner, Lauren, Litwin, Mieczyslaw, Lorbeer, Roberto, Lotufo, Paulo A., Lozano, José Eugenio, Luksiene, Dalia, Lundqvist, Annamari, Lunet, Nuno, Lytsy, Per, Ma, Guansheng, Ma, Jun, Machado-Coelho, George L. L., Machi, Suka, Maggi, Stefania, Magliano, Dianna J., Magriplis, Emmanuella, Majer, Marjeta, Makdisse, Marcia, Malhotra, Rahul, Mallikharjuna Rao, Kodavanti, Malyutina, Sofia, Manios, Yannis, Mann, Jim I., Manzato, Enzo, Margozzini, Paula, Marques-Vidal, Pedro, Marques, Larissa Pruner, Marrugat, Jaume, Martorell, Reynaldo, Mathiesen, Ellisiv B., Matijasevich, Alicia, Matsha, Tandi E., Mbanya, Jean Claude N., Mc Donald Posso, Anselmo J., McFarlane, Shelly R., McGarvey, Stephen T., McLachlan, Stela, McLean, Rachael M., McLean, Scott B., McNulty, Breige A., Mediene-Benchekor, Sounnia, Medzioniene, Jurate, Meirhaeghe, Aline, Meisinger, Christa, Menezes, Ana Maria B., Menon, Geetha R., Meshram, Indrapal I., Metspalu, Andres, Meyer, Haakon E., Mi, Jie, Mikkel, Kairit, Miller, Jody C., Minderico, Cláudia S., Francisco, Juan, Miranda, J. Jaime, Mirrakhimov, Erkin, Mišigoj-Durakovic, Marjeta, Modesti, Pietro A., Mohamed, Mostafa K., Mohammad, Kazem, Mohammadifard, Noushin, Mohan, Viswanathan, Mohanna, Salim, Mohd Yusoff, Muhammad Fadhli, Møllehave, Line T., Møller, Niels C., Molnár, Dénes, Momenan, Amirabbas, Mondo, Charles K., Monyeki, Kotsedi Daniel K., Moon, Jin Soo, Moreira, Leila B., Morejon, Alain, Moreno, Luis A., Morgan, Karen, Moschonis, George, Mossakowska, Malgorzata, Mostafa, Aya, Mota, Jorge, Esmaeel Motlagh, Mohammad, Motta, Jorge, Msyamboza, Kelias P., Mu, Thet Thet, Muiesan, Maria L., Müller-Nurasyid, Martina, Murphy, Neil, Mursu, Jaakko, Musil, Vera, Nabipour, Iraj, Nagel, Gabriele, Naidu, Balkish M., Nakamura, Harunobu, Námešná, Jana, Nang, Ei Ei K., Nangia, Vinay B., Narake, Sameer, Nauck, Matthias, Navarrete-Muñoz, Eva Maria, Ndiaye, Ndeye Coumba, Neal, William A., Nenko, Ilona, Neovius, Martin, Nervi, Flavio, Nguyen, Chung T., Nguyen, Nguyen D., Nguyen, Quang Ngoc, Nguyen, Quang V., Nieto-Martínez, Ramfis E., Niiranen, Teemu J., Ning, Guang, Ninomiya, Toshiharu, Nishtar, Sania, Noale, Marianna, Noboa, Oscar A., Noorbala, Ahmad Ali, Norat, Teresa, Noto, Davide, Al Nsour, Mohannad, O'Reilly, Dermot, Oda, Eiji, Oehlers, Glenn, Oh, Kyungwon, Ohara, Kumiko, Olinto, Maria Teresa A., Oliveira, Isabel O., Omar, Mohd Azahadi, Onat, Altan, Ong, Sok King, Ono, Lariane M., Ordunez, Pedro, Ornelas, Rui, Osmond, Clive, Ostojic, Sergej M., Ostovar, Afshin, Otero, Johanna A., Overvad, Kim, Owusu-Dabo, Ellis, Paccaud, Fred Michel, Padez, Cristina, Pahomova, Elena, Pajak, Andrzej, Palli, Domenico, Palmieri, Luigi, Pan, Wen-Harn, Panda-Jonas, Songhomitra, Panza, Francesco, Papandreou, Dimitrios, Park, Soon-Woo, Parnell, Winsome R., Parsaeian, Mahboubeh, Patel, Nikhil D., Pecin, Ivan, Pednekar, Mangesh S., Peer, Nasheeta, Peeters, Petra H., Peixoto, Sergio Viana, Peltonen, Markku, Pereira, Alexandre C., Peters, Annette, Petersmann, Astrid, Petkeviciene, Janina, Pham, Son Thai, Pigeot, Iris, Pikhart, Hynek, Pilav, Aida, Pilotto, Lorenza, Pitakaka, Freda, Piwonska, Aleksandra, Plans-Rubió, Pedro, Polašek, Ozren, Porta, Miquel, Portegies, Marileen L. P., Pourshams, Akram, Poustchi, Hossein, Pradeepa, Rajendra, Prashant, Mathur, Price, Jacqueline F., Puder, Jardena J., Puiu, Maria, Punab, Margus, Qasrawi, Radwan F., Qorbani, Mostafa, Bao, Tran Quoc, Radic, Ivana, Radisauskas, Ricardas, Rahman, Mahfuzar, Raitakari, Olli, Raj, Manu, Ramachandra Rao, Sudha, Ramachandran, Ambady, Ramos, Elisabete, Rampal, Lekhraj, Rampal, Sanjay, Rangel Reina, Daniel A., Redon, Josep, Reganit, Paul Ferdinand M., Ribeiro, Robespierre, Riboli, Elio, Rigo, Fernando, Rinke de Wit, Tobias F., Ritti-Dias, Raphael M., Robinson, Sian M., Robitaille, Cynthia, Rodríguez-Artalejo, Fernando, del Cristo Rodriguez-Perez, María, Rodríguez-Villamizar, Laura A., Rojas-Martinez, Rosalba, Romaguera, Dora, Ronkainen, Kimmo, Rosengren, Annika, Roy, Joel G. R., Rubinstein, Adolfo, Sandra Ruiz-Betancourt, Blanca, Rutkowski, Marcin, Sabanayagam, Charumathi, Sachdev, Harshpal S., Saidi, Olfa, Sakarya, Sibel, Salanave, Benoit, Salazar Martinez, Eduardo, Salmerón, Diego, Salomaa, Veikko, Salonen, Jukka T., Salvetti, Massimo, Sánchez-Abanto, Jose, Sans, Susana, Santos, Diana A., Santos, Ina S., Nunes dos Santos, Renata, Santos, Rute, Saramies, Jouko L., Sardinha, Luis B., Sarganas, Giselle, Sarrafzadegan, Nizal, Saum, Kai-Uwe, Savva, Savvas, Scazufca, Marcia, Schargrodsky, Herman, Schipf, Sabine, Schmidt, Carsten O., Schöttker, Ben, Schultsz, Constance, Schutte, Aletta E., Sein, Aye Aye, Sen, Abhijit, Senbanjo, Idowu O., Sepanlou, Sadaf G., Sharma, Sanjib K., Shaw, Jonathan E., Shibuya, Kenji, Shin, Dong Wook, Shin, Youchan, Si-Ramlee, Khairil, Siantar, Rosalynn, Sibai, Abla M., Santos Silva, Diego Augusto, Simon, Mary, Simons, Judith, Simons, Leon A., Sjöström, Michael, Skovbjerg, Sine, Slowikowska-Hilczer, Jolanta, Slusarczyk, Przemyslaw, Smeeth, Liam, Smith, Margaret C., Snijder, Marieke B., So, Hung-Kwan, Sobngwi, Eugène, Söderberg, Stefan, Solfrizzi, Vincenzo, Sonestedt, Emily, Song, Yi, Sørensen, Thorkild I. A., Soric, Maroje, Jérome, Charles Sossa, Soumare, Aicha, Staessen, Jan A., Stathopoulou, Maria G., Stavreski, Bill, Steene-Johannessen, Jostein, Stehle, Peter, Stein, Aryeh D., Stergiou, George S., Stessman, Jochanan, Stieber, Jutta, Stöckl, Doris, Stocks, Tanja, Stokwiszewski, Jakub, Stronks, Karien, Strufaldi, Maria Wany, Sun, Chien-An, Sung, Yn-Tz, Suriyawongpaisal, Paibul, Sy, Rody G., Shyong Tai, E., Tammesoo, Mari-Liis, Tamosiunas, Abdonas, Tan, Eng Joo, Tang, Xun, Tanser, Frank, Tao, Yong, Tarawneh, Mohammed Rasoul, Tarqui-Mamani, Carolina B., Tautu, Oana-Florentina, Taylor, Anne, Theobald, Holger, Theodoridis, Xenophon, Thijs, Lutgarde, Thuesen, Betina H., Tjonneland, Anne, Tolonen, Hanna K., Tolstrup, Janne S., Topbas, Murat, Topór-Madry, Roman, Tormo, María José, Torrent, Maties, Traissac, Pierre, Trichopoulos, Dimitrios, Trichopoulou, Antonia, Trinh, Oanh T. H., Trivedi, Atul, Tshepo, Lechaba, Tulloch-Reid, Marshall K., Tullu, Fikru, Tuomainen, Tomi-Pekka, Tuomilehto, Jaakko, Turley, Maria L., Tynelius, Per, Tzourio, Christophe, Ueda, Peter, Ugel, Eunice E., Ulmer, Hanno, Uusitalo, Hannu M. T., Valdivia, Gonzalo, Valvi, Damaskini, van der Schouw, Yvonne T., Van Herck, Koen, Van Minh, Hoang, van Rossem, Lenie, Van Schoor, Natasja M., van Valkengoed, Irene G. M., Vanderschueren, Dirk, Vanuzzo, Diego, Vatten, Lars, Vega, Tomas, Velasquez-Melendez, Gustavo, Veronesi, Giovanni, Monique Verschuren, W. M., Verstraeten, Roosmarijn, Victora, Cesar G., Viet, Lucie, Viikari-Juntura, Eira, Vineis, Paolo, Vioque, Jesus, Virtanen, Jyrki K., Visvikis-Siest, Sophie, Viswanathan, Bharathi, Vlasoff, Tiina, Vollenweider, Peter, Voutilainen, Sari, Wade, Alisha N., Wagner, Aline, Walton, Janette, Wan Bebakar, Wan Mohamad, Wan Mohamud, Wan Nazaimoon, Wanderley, Rildo S., Wang, Ming-Dong, Wang, Qian, Wang, Ya Xing, Wang, Ying-Wei, Wannamethee, S. Goya, Wareham, Nicholas, Wedderkopp, Niels, Weerasekera, Deepa, Whincup, Peter H., Widhalm, Kurt, Widyahening, Indah S., Wiecek, Andrzej, Wijga, Alet H., Wilks, Rainford J., Willeit, Johann, Willeit, Peter, Williams, Emmanuel A., Wilsgaard, Tom, Wojtyniak, Bogdan, Wong-McClure, Roy A., Wong, Justin Y. Y., Wong, Tien Yin, Woo, Jean, Giwercman Wu, Aleksander, Wu, Frederick C., Wu, Shouling, Xu, Haiquan, Yan, Weili, Yang, Xiaoguang, Ye, Xingwang, Yoshihara, Akihiro, Younger-Coleman, Novie O., Yusoff, Ahmad Faudzi, Zainuddin, Ahmad Ali, Zambon, Sabina, Zampelas, Antonis, Zdrojewski, Tomasz, Zeng, Yi, Zhao, Dong, Zhao, Wenhua, Zheng, Wei, Zheng, Yingfeng, Zhu, Dan, Zhussupov, Baurzhan, Zimmermann, Esther, Cisneros, Julio Zuñiga, Imperial Coll London, Univ Kent, Middlesex Univ, Harvard TH Chan, Cleveland Clin, Univ Peruana Cayetano Heredia, Univ Tehran Med Sci, Minist Hlth & Med Educ, Brandeis Univ, Mulago Hosp, Uganda Heart Inst, World Hlth Org, Univ Oxford, Univ West Indies, Univ Auckland, South African Med Res Council, Seoul Natl Univ, Natl Inst Nutr, Capital Med Univ, Robert Koch Inst, German Ctr Cardiovasc Res, Univ Zagreb, Univ Ljubljana, Uppsala Univ, Univ New South Wales, Caja Costarricense Seguro Social, Al Quds Univ, Birzeit Univ, Inst Mexicano Seguro Social, Univ Adelaide, Mahidol Univ, BRAC, Inst Nacl Ciencias Med & Nutr Salvador Zubiran, Univ Amsterdam, Minist Hlth Malaysia, Non Communicable Dis Res Ctr, BIPS, Natl Ctr Diabet & Endocrinol, Kazakh Natl Med Univ, King Abdulaziz Univ, Univ Malaysia Sabah, Luxembourg Inst Hlth, World Hlth Org Reg Off Eastern Mediterranean, Bombay Hosp & Med Res Ctr, Med Res Ctr, Lille Univ & Hosp, London Sch Hyg Trop Med, Western Norway Univ Appl Sci, Norwegian Sch Sport Sci, Bispebjerg Hosp, Frederiksberg Univ Hosp, Madras Diabet Res Fdn, Komfo Anokye Teaching Hosp, Natl Inst Publ Hlth, Univ Porto, Norwegian Inst Publ Hlth, Strasbourg Univ & Hosp, Nepal Hlth Res Council, Univ Iceland, Univ Yaounde I, Univ Fed Pelotas, Reg Author Publ Hlth, Shahid Beheshti Univ Med Sci, Indian Council Med Res, Univ Sci & Technol, Univ Autonoma Madrid, Univ Palermo, Pan Amer Hlth Org, Univ Mohammed V Rabat, Univ Pernambuco, Dalhousie Univ, Jordan Univ Sci & Technol, Univ Sydney, Univ Tunis El Manar, CAFAM Univ Fdn, Univ Utah, Lithuanian Univ Hlth Sci, Universidade de São Paulo (USP), BJ Med Coll, Chirayu Med Coll, SL Jain Hosp, Shanghai Jiao Tong Univ, Ufa Eye Res Inst, Univ Southern, Univ Greenland, Univ Oslo, Univ Gothenburg, Natl Inst Publ Hlth & Environm, Univ Turin, UCL, German Inst Human Nutr, Univ Republica, CEMIC, Toulouse Univ, Univ Hosp Varese, Minist Hlth, Univ Lausanne, Univ Ghent, Univ Cent Venezuela, Bielefeld Univ, German Canc Res Ctr, Univ Southern Denmark, Cork Inst Technol, Hadassah Hebrew Univ, Univ La Laguna, Univ Malta, Vanderbilt Univ, Canadian Fitness & Lifestyle Res Inst, Istanbul Univ, Univ Fed Juiz De Fora, Cardiol Mercato S Severino, Karolinska Inst, Univ Santiago Compostela, Duke NUS Med Sch, Natl Inst Med Stat, Acad Sinica, Capital Inst Pediat, Duke Univ, Kailuan Gen Hosp, Gertner Inst Epidemiol & Hlth Policy Res, Univ Bern, Minist Hlth & Welf, Victor Babes Univ Med & Pharm Timisoara, Murcia Reg Hlth Council, Korea Centers Dis Control & Prevent, Universidade Estadual Paulista (Unesp), Med Univ Silesia, Charles Univ Prague, Carol Davila Univ Med & Pharm, Katholieke Univ Leuven, Agcy Prevent & Social Med, Univ Southampton, IRCCS Ist Neurol Mediterraneo Neuromed, Inst Pasteur, CIBEROBN, Natl Council Res, Universidade Federal de Santa Catarina (UFSC), Eduardo Mondlane Univ, Bispebjerg & Frederiksberg Hosp, Erasmus MC, Univ Montreal, French Publ Hlth Agcy, Univ Do Vale Do Rio Dos Sinos, Natl Council Sci & Tech Res, Univ Queensland, Ist Super Sanita, Univ Cuenca, Helmholtz Zentrum Munchen, Minist Sante & Lutte Contre Sida, Cardinal Wyszynski Inst Cardiol, Univ Latvia, Natl Inst Nutr & Food Technol, Inst Hosp Del Mar dInvest Med, Univ Stellenbosch, Karadeniz Tech Univ, Natl Inst Hlth & Welf, Queens Univ Belfast, Univ Zurich, Centro Salud Villanueva Norte, Hosp Don Benito Villanueva Serena, Council Agr Res & Econ, Pontificia Univ Catolica Chile, Univ Manchester, Univ Tartu, Univ Sains Malaysia, Umea Univ, Dalarna Univ, Universidade Federal de São Paulo (UNIFESP), Hosp Univ Son Espases, Hosp Clin Porto Alegre, Univ Fed Rio Grande, Kindai Univ, Kyoto Univ, Med Univ Warsaw, Univ Catania, CIBER Epidemiol & Salud Publ, Univ KwaZulu Natal, Geneva Univ Hosp, Australian Bur Stat, Wageningen Univ, B P Koirala Inst Hlth Sci, Univ Insubria, Univ Politecn Madrid, Andes Clin Cardio Metab Studies, Natl Inst Hyg Epidemiol & Microbiol, Univ Lille 2, Inst Clin & Expt Med, Childrens Mem Hlth Inst, Alexander Technol Educ Inst, Jagiellonian Univ, Azienda Ospedaliera Univ Policlinico Vittorio Ema, Univ Novi Sad, Natl Ctr Cardiovasc Dis, Singapore Eye Res Inst, Iceland Heart Assoc, Univ Icesi, Univ Estadual Montes Claros, Kings Coll London, Int Agcy Res Canc, Healis Sekhsaria Inst Publ Hlth, Eternal Heart Care Ctr & Res Inst, Univ Ibadan, Inst Clin Effectiveness & Hlth Policy, Danish Canc Soc Res Ctr, Kyushu Univ, Tulane Univ, Chinese Ctr Dis Control & Prevent, Oulu Univ Hosp, Chron Dis Res Ctr, Univ Hong Kong, Chinese Univ Hong Kong, Univ Western Australia, Celal Bayar Univ, Fdn Oftalmol Santander, Univ Oran 1, Independent Publ Hlth Specialist, Peking Univ, Vrije Univ Amsterdam, Amer Univ Beirut, Cairo Univ, Aga Khan Univ, UHC Zagreb, Niigata Univ, Hadassah Univ Med Ctr, Norwegian Univ Sci & Technol, Heart Fdn, Natl Hlth Insurance Serv, Guangzhou 12th Hosp, Simon Fraser Univ, Heidelberg Univ, Res Ctr Prevent & Hlth, World Hlth Org Country Off, Czestochowa Tech Univ, Univ Crete, Univ Kebangsaan Malaysia, Johns Hopkins Bloomberg Sch Publ Hlth, Univ Eastern Finland, Natl Inst Epidemiol, Univ Munster, Israel Ctr Dis Control, Res Inst Primordial Prevent Non communicable Dis, Kyrgyz State Med Acad, Res Inst Child Nutr, Univ Cambridge, Med Univ Innsbruck, Muhimbili Univ Hlth & Allied Sci, Natl Canc Ctr, Inst Trop Med, Tartu Univ Clin, Minist Hlth & Qual Life, Polish Acad Sci, Univ Groningen, North West Univ, Univ Jyvaskyla, Amrita Inst Med Sci, All India Inst Med Sci, African Populat & Hlth Res Ctr, Minist Salud Publ, Sahlgrens Acad, Endocrinol & Metab Res Ctr, Food & Agr Org United Nat, Natl Univ Singapore, Tampere Univ Hosp, Univ Cape Town, West Virginia Univ, Oswaldo Cruz Fdn Rene Rachou Res Inst, Natl Taiwan Univ, Univ Chinese Acad Sci, Univ Med Greifswald, Consejeria Sanidad Junta de Castilla & Leon, Univ Fed Ouro Preto, Jikei Univ, CNR, Baker Heart & Diabet Inst, Agr Univ Athens, Hosp Israelita Albert Einstein, Shiraz Univ Med Sci, Inst Internal & Prevent Med, Harokopio Univ, Univ Otago, Univ Padua, Lausanne Univ Hosp, CIBERCV, Emory Univ, UiT Arctic Univ Norway, Cape Peninsula Univ Technol, Gorgas Mem Inst Hlth Studies, Brown Univ, Univ Edinburgh, Stat Canada, Univ Coll Dublin, INSERM, Lusofona Univ, Univ Firenze, Ain Shams Univ, Hypertens Res Ctr, Univ Pecs, Univ Limpopo, Univ Fed Rio Grande do Sul, Univ Med Sci, Univ Zaragoza, RCSI Dublin, La Trobe Univ, Int Inst Mol & Cell Biol, Ahvaz Jundishapur Univ Med Sci, Gorgas Mem Inst Publ Hlth, WHO, Dept Publ Hlth, Univ Brescia, Bushehr Univ Med Sci, Ulm Univ, Kobe Univ, Suraj Eye Inst, German Ctr Cardiovascular Res, Natl Inst Hyg & Epidemiol, Univ Pharm & Med Ho Chi Minh City, Hanoi Med Univ, Natl Hosp Endocrinol, Miami Vet Affairs Healthcare Syst, Univ Turku Tyks, Heartfile, Eastern Mediterranean Publ Hlth Network, Tachikawa Gen Hosp, Acad Hosp Paramaribo, Korea Ctr Dis Control & Prevent, Univ Vale Rio dos Sinos, Univ Madeira, MRC Lifecourse Epidemiol Unit, Aarhus Univ, Kwame Nkrumah Univ Sci & Technol, Nstitute Social & Prevent Med, Univ Coimbra, Canc Prevent & Res Inst, IRCCS Casa Sollievo Sofferenza, Zayed Univ, Catholic Univ Daegu, Jivandeep Hosp, Univ Hosp Ctr Zagreb, Univ Med Ctr Utrecht, Fundacao Oswaldo Cruz, Vietnam Natl Heart Inst, Leibniz Inst Prevent Res & Epidemiol BIPS, Univ Sarajevo, Cardiovasc Prevent Ctr, Minist Hlth & Med Serv, Publ Hlth Agcy Catalonia, Univ Split, Inst Hosp Mar Invest Med, Digest Oncol Res Ctr, Digest Dis Res Inst, Alborz Univ Med Sci, Univ Turku, India Diabet Res Fdn, Univ Putra Malaysia, Univ Malaya, Univ Valencia, Univ Philippines, Minas Gerais State Secretariat Hlth, Hlth Ctr San Agustin, PharmAccess Fdn, Univ Nove de Julho, Publ Hlth Agcy Canada, Canarian Hlth Serv, Univ Ind Santander, Inst Nacl Salud Publ, Med Univ Gdansk, Sitaram Bhartia Inst Sci & Res, Marmara Univ, Univ Helsinki, Natl Inst Hlth, Catalan Dept Hlth, Univ Lisbon, South Karelia Social & Hlth Care Dist, Isfahan Cardiovasc Res Ctr, Res & Educ Inst Child Hlth, Hosp Italiano Buenos Aires, Lagos State Univ, BP Koirala Inst Hlth Sci, Univ Tokyo, Samsung Med Ctr, St Vincents Hosp, Med Univ Lodz, London Sch Hyg & Trop Med, Acad Med Ctr, Univ Bari, Lund Univ, Univ Copenhagen, Inst Reg Sante Publ, Univ Bordeaux, Univ Leuven, Univ Bonn, Sotiria Hosp, Hadassah Univ, Natl Inst Hyg, Fu Jen Catholic Univ, Hlth Serv Murcia, IB SALUT Area Salut Menorca, Inst Rech Dev, Harvard TH Chan Sch Publ Hlth, Hellen Hlth Fdn, Govt Med Coll, Sefako Makgatho Hlth Sci Univ, Addis Ababa Univ, Dasman Diabet Inst, Univ Centrooccidental Lisandro Alvarado, Univ Tampere, Univ Utrecht, Hanoi Univ Publ Hlth, Amsterdam Publ Hlth Res Inst, Consejeria Sanidad Junta Castilla & Leon, Universidade Federal de Minas Gerais (UFMG), Finnish Inst Occupat Hlth, Univ Miguel Hernandez, North Karelian Ctr Publ Hlth, Univ Witwatersrand, Univ Strasbourg, Inst Med Res, Xinjiang Med Univ, St Georges Univ London, Med Univ Vienna, Univ Indonesia, Minist Agr, Fudan Univ, Univ Cyprus, Univ Teknol MARA, Inner Mongolia Med Univ, Zhou, B., Bentham, J., Di Cesare, M., Bixby, H., Danaei, G., Hajifathalian, K., Taddei, C., Carrillo-Larco, R.M., Djalalinia, S., Khatibzadeh, S., Lugero, C., Peykari, N., Zhang, W.Z., Bennett, J., Bilano, V., Stevens, G.A., Cowan, M.J., Riley, L.M., Chen, Z., Hambleton, I.R., Jackson, R.T., Kengne, A.P., Khang, Y.H., Laxmaiah, A., Liu, J., Malekzadeh, R., Neuhauser, H.K., Sorić, M., Starc, G., Sundström, J., Woodward, M., Ezzati, M., Abarca-Gómez, L., Abdeen, Z.A., Abu-Rmeileh, N.M., Acosta-Cazares, B., Adams, R.J., Aekplakorn, W., Afsana, K., Aguilar-Salinas, C.A., Agyemang, C., Ahmad, N.A., Ahmadvand, A., Ahrens, W., Ajlouni, K., Akhtaeva, N., Al-Raddadi, R., Ali, M.M., Ali, O., Alkerwi, A., Aly, E., Amarapurkar, D.N., Amouyel, P., Amuzu, A., Andersen, L.B., Anderssen, S.A., Ängquist, L.H., Anjana, R.M., Ansong, D., Aounallah-Skhiri, H., Araújo, J., Ariansen, I., Aris, T., Arlappa, N., Arveiler, D., Aryal, K.K., Aspelund, T., Assah, F.K., Assunção, MCF, Avdicová, M., Azevedo, A., Azizi, F., Babu, B.V., Bahijri, S., Balakrishna, N., Bamoshmoosh, M., Banach, M., Bandosz, P., Banegas, J.R., Barbagallo, C.M., Barceló, A., Barkat, A., Barros, AJD, Barros, M.V., Bata, I., Batieha, A.M., Batyrbek, A., Baur, L.A., Beaglehole, R., Romdhane, H.B., Benet, M., Benson, L.S., Bernabe-Ortiz, A., Bernotiene, G., Bettiol, H., Bhagyalaxmi, A., Bharadwaj, S., Bhargava, S.K., Bi, Y., Bikbov, M., Bista, B., Bjerregaard, P., Bjertness, E., Bjertness, M.B., Björkelund, C., Blokstra, A., Bo, S., Bobak, M., Boeing, H., Boggia, J.G., Boissonnet, C.P., Bongard, V., Borchini, R., Bovet, P., Braeckman, L., Brajkovich, I., Branca, F., Breckenkamp, J., Brenner, H., Brewster, L.M., Bruno, G., Bueno-de-Mesquita, HBA, Bugge, A., Burns, C., Bursztyn, M., de León, A.C., Cacciottolo, J., Cai, H., Cameron, C., Can, G., Cândido, APC, Capuano, V., Cardoso, V.C., Carlsson, A.C., Carvalho, M.J., Casanueva, F.F., Casas, J.P., Caserta, C.A., Chamukuttan, S., Chan, A.W., Chan, Q., Chaturvedi, H.K., Chaturvedi, N., Chen, C.J., Chen, F., Chen, H., Chen, S., Cheng, C.Y., Dekkaki, I.C., Chetrit, A., Chiolero, A., Chiou, S.T., Chirita-Emandi, A., Chirlaque, M.D., Cho, B., Cho, Y., Christofaro, D.G., Chudek, J., Cifkova, R., Cinteza, E., Claessens, F., Clays, E., Concin, H., Cooper, C., Cooper, R., Coppinger, T.C., Costanzo, S., Cottel, D., Cowell, C., Craig, C.L., Crujeiras, A.B., Cruz, J.J., D'Arrigo, G., d'Orsi, E., Dallongeville, J., Damasceno, A., Dankner, R., Dantoft, T.M., Dauchet, L., Davletov, K., De Backer, G., De Bacquer, D., de Gaetano, G., De Henauw, S., de Oliveira, P.D., De Smedt, D., Deepa, M., Dehghan, A., Delisle, H., Deschamps, V., Dhana, K., Di Castelnuovo, A.F., Dias-da-Costa, J.S., Diaz, A., Dickerson, T.T., Do, HTP, Donfrancesco, C., Donoso, S.P., Döring, A., Dorobantu, M., Doua, K., Drygas, W., Dulskiene, V., Džakula, A., Dzerve, V., Dziankowska-Zaborszczyk, E., Eggertsen, R., Ekelund, U., El Ati, J., Elliott, P., Elosua, R., Erasmus, R.T., Erem, C., Eriksen, L., Eriksson, J.G., Escobedo-de la Peña, J., Evans, A., Faeh, D., Fall, C.H., Farzadfar, F., Felix-Redondo, F.J., Ferguson, T.S., Fernandes, R.A., Fernández-Bergés, D., Ferrante, D., Ferrari, M., Ferreccio, C., Ferrieres, J., Finn, J.D., Fischer, K., Föger, B., Foo, L.H., Forslund, A.S., Forsner, M., Fouad, H.M., Francis, D.K., do Carmo Franco, M., Franco, O.H., Frontera, G., Fuchs, F.D., Fuchs, S.C., Fujita, Y., Furusawa, T., Gaciong, Z., Galvano, F., Garcia-de-la-Hera, M., Gareta, D., Garnett, S.P., Gaspoz, J.M., Gasull, M., Gates, L., Geleijnse, J.M., Ghasemian, A., Ghimire, A., Giampaoli, S., Gianfagna, F., Gill, T.K., Giovannelli, J., Goldsmith, R.A., Gonçalves, H., Gonzalez-Gross, M., González-Rivas, J.P., Gorbea, M.B., Gottrand, F., Graff-Iversen, S., Grafnetter, D., Grajda, A., Grammatikopoulou, M.G., Gregor, R.D., Grodzicki, T., Grøntved, A., Grosso, G., Gruden, G., Grujic, V., Gu, D., Guan, O.P., Gudmundsson, E.F., Gudnason, V., Guerrero, R., Guessous, I., Guimaraes, A.L., Gulliford, M.C., Gunnlaugsdottir, J., Gunter, M., Gupta, P.C., Gupta, R., Gureje, O., Gurzkowska, B., Gutierrez, L., Gutzwiller, F., Hadaegh, F., Halkjær, J., Hardy, R., Hari Kumar, R., Hata, J., Hayes, A.J., He, J., He, Y., Elisabeth, M., Henriques, A., Cadena, L.H., Herrala, S., Heshmat, R., Hihtaniemi, I.T., Ho, S.Y., Ho, S.C., Hobbs, M., Hofman, A., Dinc, G.H., Horimoto, ARVR, Hormiga, C.M., Horta, B.L., Houti, L., Howitt, C., Htay, T.T., Htet, A.S., Than Htike, M.M., Hu, Y., Huerta, J.M., Huisman, M., Husseini, A.S., Huybrechts, I., Hwalla, N., Iacoviello, L., Iannone, A.G., Ibrahim, M.M., Wong, N.I., Ikeda, N., Ikram, M.A., Irazola, V.E., Islam, M., Al-Safi Ismail, A., Ivkovic, V., Iwasaki, M., Jacobs, J.M., Jaddou, H., Jafar, T., Jamrozik, K., Janszky, I., Jasienska, G., Jelaković, A., Jelaković, B., Jennings, G., Jeong, S.L., Jiang, C.Q., Joffres, M., Johansson, M., Jokelainen, J.J., Jonas, J.B., Jørgensen, T., Joshi, P., Jóźwiak, J., Juolevi, A., Jurak, G., Jureša, V., Kaaks, R., Kafatos, A., Kajantie, E.O., Kalter-Leibovici, O., Kamaruddin, N.A., Karki, K.B., Kasaeian, A., Katz, J., Kauhanen, J., Kaur, P., Kavousi, M., Kazakbaeva, G., Keil, U., Boker, L.K., Keinänen-Kiukaanniemi, S., Kelishadi, R., Kemper, HCG, Kerimkulova, A., Kersting, M., Key, T., Khader, Y.S., Khalili, D., Khateeb, M., Khaw, K.T., Kiechl-Kohlendorfer, U., Kiechl, S., Killewo, J., Kim, J., Kim, Y.Y., Klumbiene, J., Knoflach, M., Kolle, E., Kolsteren, P., Korrovits, P., Koskinen, S., Kouda, K., Kowlessur, S., Koziel, S., Kriemler, S., Kristensen, P.L., Krokstad, S., Kromhout, D., Kruger, H.S., Kubinova, R., Kuciene, R., Kuh, D., Kujala, U.M., Kulaga, Z., Krishna Kumar, R., Kurjata, P., Kusuma, Y.S., Kuulasmaa, K., Kyobutungi, C., Laatikainen, T., Lachat, C., Lam, T.H., Landrove, O., Lanska, V., Lappas, G., Larijani, B., Laugsand, L.E., Le Nguyen Bao, K., Le, T.D., Leclercq, C., Lee, J., Lehtimäki, T., León-Muñoz, L.M., Levitt, N.S., Li, Y., Lilly, C.L., Lim, W.Y., Lima-Costa, M.F., Lin, H.H., Lin, X., Lind, L., Linneberg, A., Lissner, L., Litwin, M., Lorbeer, R., Lotufo, P.A., Lozano, J.E., Luksiene, D., Lundqvist, A., Lunet, N., Lytsy, P., Ma, G., Ma, J., Machado-Coelho, GLL, Machi, S., Maggi, S., Magliano, D.J., Magriplis, E., Majer, M., Makdisse, M., Malhotra, R., Mallikharjuna Rao, K., Malyutina, S., Manios, Y., Mann, J.I., Manzato, E., Margozzini, P., Marques-Vidal, P., Marques, L.P., Marrugat, J., Martorell, R., Mathiesen, E.B., Matijasevich, A., Matsha, T.E., Mbanya, JCN, Mc Donald Posso, A.J., McFarlane, S.R., McGarvey, S.T., McLachlan, S., McLean, R.M., McLean, S.B., McNulty, B.A., Mediene-Benchekor, S., Medzioniene, J., Meirhaeghe, A., Meisinger, C., Menezes, AMB, Menon, G.R., Meshram, I.I., Metspalu, A., Meyer, H.E., Mi, J., Mikkel, K., Miller, J.C., Minderico, C.S., Francisco, J., Miranda, J.J., Mirrakhimov, E., Mišigoj-Durakovic, M., Modesti, P.A., Mohamed, M.K., Mohammad, K., Mohammadifard, N., Mohan, V., Mohanna, S., Mohd Yusoff, M.F., Møllehave, L.T., Møller, N.C., Molnár, D., Momenan, A., Mondo, C.K., Monyeki, KDK, Moon, J.S., Moreira, L.B., Morejon, A., Moreno, L.A., Morgan, K., Moschonis, G., Mossakowska, M., Mostafa, A., Mota, J., Esmaeel Motlagh, M., Motta, J., Msyamboza, K.P., Mu, T.T., Muiesan, M.L., Müller-Nurasyid, M., Murphy, N., Mursu, J., Musil, V., Nabipour, I., Nagel, G., Naidu, B.M., Nakamura, H., Námešná, J., Nang, EEK, Nangia, V.B., Narake, S., Nauck, M., Navarrete-Muñoz, E.M., Ndiaye, N.C., Neal, W.A., Nenko, I., Neovius, M., Nervi, F., Nguyen, C.T., Nguyen, N.D., Nguyen, Q.N., Nguyen, Q.V., Nieto-Martínez, R.E., Niiranen, T.J., Ning, G., Ninomiya, T., Nishtar, S., Noale, M., Noboa, O.A., Noorbala, A.A., Norat, T., Noto, D., Al Nsour, M., O'Reilly, D., Oda, E., Oehlers, G., Oh, K., Ohara, K., Olinto, MTA, Oliveira, I.O., Omar, M.A., Onat, A., Ong, S.K., Ono, L.M., Ordunez, P., Ornelas, R., Osmond, C., Ostojic, S.M., Ostovar, A., Otero, J.A., Overvad, K., Owusu-Dabo, E., Paccaud, F.M., Padez, C., Pahomova, E., Pajak, A., Palli, D., Palmieri, L., Pan, W.H., Panda-Jonas, S., Panza, F., Papandreou, D., Park, S.W., Parnell, W.R., Parsaeian, M., Patel, N.D., Pecin, I., Pednekar, M.S., Peer, N., Peeters, P.H., Peixoto, S.V., Peltonen, M., Pereira, A.C., Peters, A., Petersmann, A., Petkeviciene, J., Pham, S.T., Pigeot, I., Pikhart, H., Pilav, A., Pilotto, L., Pitakaka, F., Piwonska, A., Plans-Rubió, P., Polašek, O., Porta, M., Portegies, MLP, Pourshams, A., Poustchi, H., Pradeepa, R., Prashant, M., Price, J.F., Puder, J.J., Puiu, M., Punab, M., Qasrawi, R.F., Qorbani, M., Bao, T.Q., Radic, I., Radisauskas, R., Rahman, M., Raitakari, O., Raj, M., Ramachandra Rao, S., Ramachandran, A., Ramos, E., Rampal, L., Rampal, S., Rangel Reina, D.A., Redon, J., Reganit, PFM, Ribeiro, R., Riboli, E., Rigo, F., Rinke de Wit, T.F., Ritti-Dias, R.M., Robinson, S.M., Robitaille, C., Rodríguez-Artalejo, F., Del Cristo Rodriguez-Perez, M., Rodríguez-Villamizar, L.A., Rojas-Martinez, R., Romaguera, D., Ronkainen, K., Rosengren, A., Roy, JGR, Rubinstein, A., Sandra Ruiz-Betancourt, B., Rutkowski, M., Sabanayagam, C., Sachdev, H.S., Saidi, O., Sakarya, S., Salanave, B., Salazar Martinez, E., Salmerón, D., Salomaa, V., Salonen, J.T., Salvetti, M., Sánchez-Abanto, J., Sans, S., Santos, D.A., Santos, I.S., Nunes Dos Santos, R., Santos, R., Saramies, J.L., Sardinha, L.B., Sarganas, G., Sarrafzadegan, N., Saum, K.U., Savva, S., Scazufca, M., Schargrodsky, H., Schipf, S., Schmidt, C.O., Schöttker, B., Schultsz, C., Schutte, A.E., Sein, A.A., Sen, A., Senbanjo, I.O., Sepanlou, S.G., Sharma, S.K., Shaw, J.E., Shibuya, K., Shin, D.W., Shin, Y., Si-Ramlee, K., Siantar, R., Sibai, A.M., Santos Silva, D.A., Simon, M., Simons, J., Simons, L.A., Sjöström, M., Skovbjerg, S., Slowikowska-Hilczer, J., Slusarczyk, P., Smeeth, L., Smith, M.C., Snijder, M.B., So, H.K., Sobngwi, E., Söderberg, S., Solfrizzi, V., Sonestedt, E., Song, Y., Sørensen, TIA, Soric, M., Jérome, C.S., Soumare, A., Staessen, J.A., Stathopoulou, M.G., Stavreski, B., Steene-Johannessen, J., Stehle, P., Stein, A.D., Stergiou, G.S., Stessman, J., Stieber, J., Stöckl, D., Stocks, T., Stokwiszewski, J., Stronks, K., Strufaldi, M.W., Sun, C.A., Sung, Y.T., Suriyawongpaisal, P., Sy, R.G., Shyong Tai, E., Tammesoo, M.L., Tamosiunas, A., Tan, E.J., Tang, X., Tanser, F., Tao, Y., Tarawneh, M.R., Tarqui-Mamani, C.B., Tautu, O.F., Taylor, A., Theobald, H., Theodoridis, X., Thijs, L., Thuesen, B.H., Tjonneland, A., Tolonen, H.K., Tolstrup, J.S., Topbas, M., Topór-Madry, R., Tormo, M.J., Torrent, M., Traissac, P., Trichopoulos, D., Trichopoulou, A., Trinh, OTH, Trivedi, A., Tshepo, L., Tulloch-Reid, M.K., Tullu, F., Tuomainen, T.P., Tuomilehto, J., Turley, M.L., Tynelius, P., Tzourio, C., Ueda, P., Ugel, E.E., Ulmer, H., Uusitalo, HMT, Valdivia, G., Valvi, D., van der Schouw, Y.T., Van Herck, K., Van Minh, H., van Rossem, L., Van Schoor, N.M., van Valkengoed, IGM, Vanderschueren, D., Vanuzzo, D., Vatten, L., Vega, T., Velasquez-Melendez, G., Veronesi, G., Monique Verschuren, W.M., Verstraeten, R., Victora, C.G., Viet, L., Viikari-Juntura, E., Vineis, P., Vioque, J., Virtanen, J.K., Visvikis-Siest, S., Viswanathan, B., Vlasoff, T., Vollenweider, P., Voutilainen, S., Wade, A.N., Wagner, A., Walton, J., Wan Bebakar, W.M., Wan Mohamud, W.N., Wanderley, R.S., Wang, M.D., Wang, Q., Wang, Y.X., Wang, Y.W., Wannamethee, S.G., Wareham, N., Wedderkopp, N., Weerasekera, D., Whincup, P.H., Widhalm, K., Widyahening, I.S., Wiecek, A., Wijga, A.H., Wilks, R.J., Willeit, J., Willeit, P., Williams, E.A., Wilsgaard, T., Wojtyniak, B., Wong-McClure, R.A., Wong, JYY, Wong, T.Y., Woo, J., Giwercman Wu, A., Wu, F.C., Wu, S., Xu, H., Yan, W., Yang, X., Ye, X., Yiallouros, P.K., Yoshihara, A., Younger-Coleman, N.O., Yusoff, A.F., Zainuddin, A.A., Zambon, S., Zampelas, A., Zdrojewski, T., Zeng, Y., Zhao, D., Zhao, W., Zheng, W., Zheng, Y., Zhu, D., Zhussupov, B., Zimmermann, E., Cisneros, J.Z., Zhou, Bin, Bentham, Jame, Di Cesare, Mariachiara, Bixby, Honor, Danaei, Goodarz, Hajifathalian, Kaveh, Taddei, Cristina, Carrillo-Larco, Rodrigo M, Djalalinia, Shirin, Khatibzadeh, Shahab, Lugero, Charle, Peykari, Niloofar, Zhang, Wan Zhu, Bennett, Jame, Bilano, Ver, Stevens, Gretchen A, Cowan, Melanie J, Riley, Leanne M, Chen, Zhengming, Hambleton, Ian R, Jackson, Rod T, Kengne, Andre Pascal, Khang, Young-Ho, Laxmaiah, Avula, Liu, Jing, Malekzadeh, Reza, Neuhauser, Hannelore K, Sorić, Maroje, Starc, Gregor, Sundström, Johan, Woodward, Mark, Ezzati, Majid, Abarca-Gómez, Leandra, Abdeen, Ziad A, Abu-Rmeileh, Niveen M, Acosta-Cazares, Benjamin, Adams, Robert J, Aekplakorn, Wichai, Afsana, Kaosar, Aguilar-Salinas, Carlos A, Agyemang, Charle, Ahmad, Noor Ani, Ahmadvand, Alireza, Ahrens, Wolfgang, Ajlouni, Kamel, Akhtaeva, Nazgul, Al-Raddadi, Rajaa, Ali, Mohamed M, Ali, Osman, Alkerwi, Ala'a, Aly, Eman, Amarapurkar, Deepak N, Amouyel, Philippe, Amuzu, Antoinette, Andersen, Lars Bo, Anderssen, Sigmund A, Ängquist, Lars H, Anjana, Ranjit Mohan, Ansong, Daniel, Aounallah-Skhiri, Hajer, Araújo, Joana, Ariansen, Inger, Aris, Tahir, Arlappa, Nimmathota, Arveiler, Dominique, Aryal, Krishna K, Aspelund, Thor, Assah, Felix K, Assunção, Maria Cecília F, Avdicová, Mária, Azevedo, Ana, Azizi, Fereidoun, Babu, Bontha V, Bahijri, Suhad, Balakrishna, Nagalla, Bamoshmoosh, Mohamed, Banach, Maciej, Bandosz, Piotr, Banegas, José R, Barbagallo, Carlo M, Barceló, Alberto, Barkat, Amina, Barros, Aluisio J D, Barros, Mauro V, Bata, Iqbal, Batieha, Anwar M, Batyrbek, Assembekov, Baur, Louise A, Beaglehole, Robert, Romdhane, Habiba Ben, Benet, Mikhail, Benson, Lowell S, Bernabe-Ortiz, Antonio, Bernotiene, Gailute, Bettiol, Heloisa, Bhagyalaxmi, Aroor, Bharadwaj, Sumit, Bhargava, Santosh K, Bi, Yufang, Bikbov, Mukharram, Bista, Bihungum, Bjerregaard, Peter, Bjertness, Espen, Bjertness, Marius B, Björkelund, Cecilia, Blokstra, Anneke, Bo, Simona, Bobak, Martin, Boeing, Heiner, Boggia, Jose G, Boissonnet, Carlos P, Bongard, Vanina, Borchini, Rossana, Bovet, Pascal, Braeckman, Lutgart, Brajkovich, Imperia, Branca, Francesco, Breckenkamp, Juergen, Brenner, Hermann, Brewster, Lizzy M, Bruno, Graziella, Bueno-de-Mesquita, H B(as), Bugge, Anna, Burns, Con, Bursztyn, Michael, de León, Antonio Cabrera, Cacciottolo, Joseph, Cai, Hui, Cameron, Christine, Can, Günay, Cândido, Ana Paula C, Capuano, Vincenzo, Cardoso, Viviane C, Carlsson, Axel C, Carvalho, Maria J, Casanueva, Felipe F, Casas, Juan-Pablo, Caserta, Carmelo A, Chamukuttan, Snehalatha, Chan, Angelique W, Chan, Queenie, Chaturvedi, Himanshu K, Chaturvedi, Nishi, Chen, Chien-Jen, Chen, Fangfang, Chen, Huashuai, Chen, Shuohua, Cheng, Ching-Yu, Dekkaki, Imane Cherkaoui, Chetrit, Angela, Chiolero, Arnaud, Chiou, Shu-Ti, Chirita-Emandi, Adela, Chirlaque, María-Dolore, Cho, Belong, Cho, Yumi, Christofaro, Diego G, Chudek, Jerzy, Cifkova, Renata, Cinteza, Eliza, Claessens, Frank, Clays, El, Concin, Han, Cooper, Cyru, Cooper, Rachel, Coppinger, Tara C, Costanzo, Simona, Cottel, Dominique, Cowell, Chri, Craig, Cora L, Crujeiras, Ana B, Cruz, Juan J, D'Arrigo, Graziella, d'Orsi, Eleonora, Dallongeville, Jean, Damasceno, Albertino, Dankner, Rachel, Dantoft, Thomas M, Dauchet, Luc, Davletov, Kairat, De Backer, Guy, De Bacquer, Dirk, de Gaetano, Giovanni, De Henauw, Stefaan, de Oliveira, Paula Duarte, De Smedt, Delphine, Deepa, Mohan, Dehghan, Abba, Delisle, Hélène, Deschamps, Valérie, Dhana, Klodian, Di Castelnuovo, Augusto F, Dias-da-Costa, Juvenal Soare, Diaz, Alejandro, Dickerson, Ty T, Do, Ha T P, Donfrancesco, Chiara, Donoso, Silvana P, Döring, Angela, Dorobantu, Maria, Doua, Kouamelan, Drygas, Wojciech, Dulskiene, Virginija, Džakula, Aleksandar, Dzerve, Vilni, Dziankowska-Zaborszczyk, Elzbieta, Eggertsen, Robert, Ekelund, Ulf, El Ati, Jalila, Elliott, Paul, Elosua, Roberto, Erasmus, Rajiv T, Erem, Cihangir, Eriksen, Louise, Eriksson, Johan G, Escobedo-de la Peña, Jorge, Evans, Alun, Faeh, David, Fall, Caroline H, Farzadfar, Farshad, Felix-Redondo, Francisco J, Ferguson, Trevor S, Fernandes, Romulo A, Fernández-Bergés, Daniel, Ferrante, Daniel, Ferrari, Marika, Ferreccio, Catterina, Ferrieres, Jean, Finn, Joseph D, Fischer, Krista, Föger, Bernhard, Foo, Leng Huat, Forslund, Ann-Sofie, Forsner, Maria, Fouad, Heba M, Francis, Damian K, do Carmo Franco, Maria, Franco, Oscar H, Frontera, Guillermo, Fuchs, Flavio D, Fuchs, Sandra C, Fujita, Yuki, Furusawa, Takuro, Gaciong, Zbigniew, Galvano, Fabio, Garcia-de-la-Hera, Manoli, Gareta, Dickman, Garnett, Sarah P, Gaspoz, Jean-Michel, Gasull, Magda, Gates, Louise, Geleijnse, Johanna M, Ghasemian, Anoosheh, Ghimire, Anup, Giampaoli, Simona, Gianfagna, Francesco, Gill, Tiffany K, Giovannelli, Jonathan, Goldsmith, Rebecca A, Gonçalves, Helen, Gonzalez-Gross, Marcela, González-Rivas, Juan P, Gorbea, Mariano Bonet, Gottrand, Frederic, Graff-Iversen, Sidsel, Grafnetter, Dušan, Grajda, Aneta, Grammatikopoulou, Maria G, Gregor, Ronald D, Grodzicki, Tomasz, Grøntved, Ander, Grosso, Giuseppe, Gruden, Gabriella, Grujic, Vera, Gu, Dongfeng, Guan, Ong Peng, Gudmundsson, Elias F, Gudnason, Vilmundur, Guerrero, Ramiro, Guessous, Idri, Guimaraes, Andre L, Gulliford, Martin C, Gunnlaugsdottir, Johanna, Gunter, Marc, Gupta, Prakash C, Gupta, Rajeev, Gureje, Oye, Gurzkowska, Beata, Gutierrez, Laura, Gutzwiller, Felix, Hadaegh, Farzad, Halkjær, Jytte, Hardy, Rebecca, Hari Kumar, Rachakulla, Hata, Jun, Hayes, Alison J, He, Jiang, He, Yuna, Elisabeth, Marleen, Henriques, Ana, Cadena, Leticia Hernandez, Herrala, Sauli, Heshmat, Ramin, Hihtaniemi, Ilpo Tapani, Ho, Sai Yin, Ho, Suzanne C, Hobbs, Michael, Hofman, Albert, Dinc, Gonul Horasan, Horimoto, Andrea R V R, Hormiga, Claudia M, Horta, Bernardo L, Houti, Leila, Howitt, Christina, Htay, Thein Thein, Htet, Aung Soe, Than Htike, Maung Maung, Hu, Yonghua, Huerta, José María, Huisman, Martijn, Husseini, Abdullatif S, Huybrechts, Inge, Hwalla, Nahla, Iacoviello, Licia, Iannone, Anna G, Ibrahim, Mohsen M, Wong, Norazizah Ibrahim, Ikeda, Nayu, Ikram, M Arfan, Irazola, Vilma E, Islam, Muhammad, al-Safi Ismail, Aziz, Ivkovic, Vanja, Iwasaki, Masanori, Jacobs, Jeremy M, Jaddou, Hashem, Jafar, Tazeen, Jamrozik, Konrad, Janszky, Imre, Jasienska, Grazyna, Jelaković, Ana, Jelaković, Bojan, Jennings, Garry, Jeong, Seung-lyeal, Jiang, Chao Qiang, Joffres, Michel, Johansson, Mattia, Jokelainen, Jari J, Jonas, Jost B, Jørgensen, Torben, Joshi, Pradeep, Jóźwiak, Jacek, Juolevi, Anne, Jurak, Gregor, Jureša, Vesna, Kaaks, Rudolf, Kafatos, Anthony, Kajantie, Eero O, Kalter-Leibovici, Ofra, Kamaruddin, Nor Azmi, Karki, Khem B, Kasaeian, Amir, Katz, Joanne, Kauhanen, Jussi, Kaur, Prabhdeep, Kavousi, Maryam, Kazakbaeva, Gyulli, Keil, Ulrich, Boker, Lital Keinan, Keinänen-Kiukaanniemi, Sirkka, Kelishadi, Roya, Kemper, Han C G, Kengne, Andre P, Kerimkulova, Alina, Kersting, Mathilde, Key, Timothy, Khader, Yousef Saleh, Khalili, Davood, Khateeb, Mohammad, Khaw, Kay-Tee, Kiechl-Kohlendorfer, Ursula, Kiechl, Stefan, Killewo, Japhet, Kim, Jeongseon, Kim, Yeon-Yong, Klumbiene, Jurate, Knoflach, Michael, Kolle, Elin, Kolsteren, Patrick, Korrovits, Paul, Koskinen, Seppo, Kouda, Katsuyasu, Kowlessur, Sudhir, Koziel, Slawomir, Kriemler, Susi, Kristensen, Peter Lund, Krokstad, Steinar, Kromhout, Daan, Kruger, Herculina S, Kubinova, Ruzena, Kuciene, Renata, Kuh, Diana, Kujala, Urho M, Kulaga, Zbigniew, Krishna Kumar, R, Kurjata, Pawel, Kusuma, Yadlapalli S, Kuulasmaa, Kari, Kyobutungi, Catherine, Laatikainen, Tiina, Lachat, Carl, Lam, Tai Hing, Landrove, Orlando, Lanska, Vera, Lappas, Georg, Larijani, Bagher, Laugsand, Lars E, Le Nguyen Bao, Khanh, Le, Tuyen D, Leclercq, Catherine, Lee, Jeannette, Lee, Jeonghee, Lehtimäki, Terho, León-Muñoz, Luz M, Levitt, Naomi S, Li, Yanping, Lilly, Christa L, Lim, Wei-Yen, Lima-Costa, M Fernanda, Lin, Hsien-Ho, Lin, Xu, Lind, Lar, Linneberg, Allan, Lissner, Lauren, Litwin, Mieczyslaw, Lorbeer, Roberto, Lotufo, Paulo A, Lozano, José Eugenio, Luksiene, Dalia, Lundqvist, Annamari, Lunet, Nuno, Lytsy, Per, Ma, Guansheng, Ma, Jun, Machado-Coelho, George L L, Machi, Suka, Maggi, Stefania, Magliano, Dianna J, Magriplis, Emmanuella, Majer, Marjeta, Makdisse, Marcia, Malhotra, Rahul, Mallikharjuna Rao, Kodavanti, Malyutina, Sofia, Manios, Yanni, Mann, Jim I, Manzato, Enzo, Margozzini, Paula, Marques-Vidal, Pedro, Marques, Larissa Pruner, Marrugat, Jaume, Martorell, Reynaldo, Mathiesen, Ellisiv B, Matijasevich, Alicia, Matsha, Tandi E, Mbanya, Jean Claude N, Mc Donald Posso, Anselmo J, McFarlane, Shelly R, McGarvey, Stephen T, McLachlan, Stela, McLean, Rachael M, McLean, Scott B, McNulty, Breige A, Mediene-Benchekor, Sounnia, Medzioniene, Jurate, Meirhaeghe, Aline, Meisinger, Christa, Menezes, Ana Maria B, Menon, Geetha R, Meshram, Indrapal I, Metspalu, Andre, Meyer, Haakon E, Mi, Jie, Mikkel, Kairit, Miller, Jody C, Minderico, Cláudia S, Francisco, Juan, Miranda, J Jaime, Mirrakhimov, Erkin, Mišigoj-Durakovic, Marjeta, Modesti, Pietro A, Mohamed, Mostafa K, Mohammad, Kazem, Mohammadifard, Noushin, Mohan, Viswanathan, Mohanna, Salim, Mohd Yusoff, Muhammad Fadhli, Møllehave, Line T, Møller, Niels C, Molnár, Déne, Momenan, Amirabba, Mondo, Charles K, Monyeki, Kotsedi Daniel K, Moon, Jin Soo, Moreira, Leila B, Morejon, Alain, Moreno, Luis A, Morgan, Karen, Moschonis, George, Mossakowska, Malgorzata, Mostafa, Aya, Mota, Jorge, Esmaeel Motlagh, Mohammad, Motta, Jorge, Msyamboza, Kelias P, Mu, Thet Thet, Muiesan, Maria L, Müller-Nurasyid, Martina, Murphy, Neil, Mursu, Jaakko, Musil, Vera, Nabipour, Iraj, Nagel, Gabriele, Naidu, Balkish M, Nakamura, Harunobu, Námešná, Jana, Nang, Ei Ei K, Nangia, Vinay B, Narake, Sameer, Nauck, Matthia, Navarrete-Muñoz, Eva Maria, Ndiaye, Ndeye Coumba, Neal, William A, Nenko, Ilona, Neovius, Martin, Nervi, Flavio, Nguyen, Chung T, Nguyen, Nguyen D, Nguyen, Quang Ngoc, Nguyen, Quang V, Nieto-Martínez, Ramfis E, Niiranen, Teemu J, Ning, Guang, Ninomiya, Toshiharu, Nishtar, Sania, Noale, Marianna, Noboa, Oscar A, Noorbala, Ahmad Ali, Norat, Teresa, Noto, Davide, Al Nsour, Mohannad, O'Reilly, Dermot, Oda, Eiji, Oehlers, Glenn, Oh, Kyungwon, Ohara, Kumiko, Olinto, Maria Teresa A, Oliveira, Isabel O, Omar, Mohd Azahadi, Onat, Altan, Ong, Sok King, Ono, Lariane M, Ordunez, Pedro, Ornelas, Rui, Osmond, Clive, Ostojic, Sergej M, Ostovar, Afshin, Otero, Johanna A, Overvad, Kim, Owusu-Dabo, Elli, Paccaud, Fred Michel, Padez, Cristina, Pahomova, Elena, Pajak, Andrzej, Palli, Domenico, Palmieri, Luigi, Pan, Wen-Harn, Panda-Jonas, Songhomitra, Panza, Francesco, Papandreou, Dimitrio, Park, Soon-Woo, Parnell, Winsome R, Parsaeian, Mahboubeh, Patel, Nikhil D, Pecin, Ivan, Pednekar, Mangesh S, Peer, Nasheeta, Peeters, Petra H, Peixoto, Sergio Viana, Peltonen, Markku, Pereira, Alexandre C, Peters, Annette, Petersmann, Astrid, Petkeviciene, Janina, Pham, Son Thai, Pigeot, Iri, Pikhart, Hynek, Pilav, Aida, Pilotto, Lorenza, Pitakaka, Freda, Piwonska, Aleksandra, Plans-Rubió, Pedro, Polašek, Ozren, Porta, Miquel, Portegies, Marileen L P, Pourshams, Akram, Poustchi, Hossein, Pradeepa, Rajendra, Prashant, Mathur, Price, Jacqueline F, Puder, Jardena J, Puiu, Maria, Punab, Margu, Qasrawi, Radwan F, Qorbani, Mostafa, Bao, Tran Quoc, Radic, Ivana, Radisauskas, Ricarda, Rahman, Mahfuzar, Raitakari, Olli, Raj, Manu, Ramachandra Rao, Sudha, Ramachandran, Ambady, Ramos, Elisabete, Rampal, Lekhraj, Rampal, Sanjay, Rangel Reina, Daniel A, Redon, Josep, Reganit, Paul Ferdinand M, Ribeiro, Robespierre, Riboli, Elio, Rigo, Fernando, Rinke de Wit, Tobias F, Ritti-Dias, Raphael M, Robinson, Sian M, Robitaille, Cynthia, Rodríguez-Artalejo, Fernando, del Cristo Rodriguez-Perez, María, Rodríguez-Villamizar, Laura A, Rojas-Martinez, Rosalba, Romaguera, Dora, Ronkainen, Kimmo, Rosengren, Annika, Roy, Joel G R, Rubinstein, Adolfo, Sandra Ruiz-Betancourt, Blanca, Rutkowski, Marcin, Sabanayagam, Charumathi, Sachdev, Harshpal S, Saidi, Olfa, Sakarya, Sibel, Salanave, Benoit, Salazar Martinez, Eduardo, Salmerón, Diego, Salomaa, Veikko, Salonen, Jukka T, Salvetti, Massimo, Sánchez-Abanto, Jose, Sans, Susana, Santos, Diana A, Santos, Ina S, Nunes dos Santos, Renata, Santos, Rute, Saramies, Jouko L, Sardinha, Luis B, Sarganas, Giselle, Sarrafzadegan, Nizal, Saum, Kai-Uwe, Savva, Savva, Scazufca, Marcia, Schargrodsky, Herman, Schipf, Sabine, Schmidt, Carsten O, Schöttker, Ben, Schultsz, Constance, Schutte, Aletta E, Sein, Aye Aye, Sen, Abhijit, Senbanjo, Idowu O, Sepanlou, Sadaf G, Sharma, Sanjib K, Shaw, Jonathan E, Shibuya, Kenji, Shin, Dong Wook, Shin, Youchan, Si-Ramlee, Khairil, Siantar, Rosalynn, Sibai, Abla M, Santos Silva, Diego Augusto, Simon, Mary, Simons, Judith, Simons, Leon A, Sjöström, Michael, Skovbjerg, Sine, Slowikowska-Hilczer, Jolanta, Slusarczyk, Przemyslaw, Smeeth, Liam, Smith, Margaret C, Snijder, Marieke B, So, Hung-Kwan, Sobngwi, Eugène, Söderberg, Stefan, Solfrizzi, Vincenzo, Sonestedt, Emily, Song, Yi, Sørensen, Thorkild I A, Soric, Maroje, Jérome, Charles Sossa, Soumare, Aicha, Staessen, Jan A, Stathopoulou, Maria G, Stavreski, Bill, Steene-Johannessen, Jostein, Stehle, Peter, Stein, Aryeh D, Stergiou, George S, Stessman, Jochanan, Stieber, Jutta, Stöckl, Dori, Stocks, Tanja, Stokwiszewski, Jakub, Stronks, Karien, Strufaldi, Maria Wany, Sun, Chien-An, Sung, Yn-Tz, Suriyawongpaisal, Paibul, Sy, Rody G, Shyong Tai, E, Tammesoo, Mari-Lii, Tamosiunas, Abdona, Tan, Eng Joo, Tang, Xun, Tanser, Frank, Tao, Yong, Tarawneh, Mohammed Rasoul, Tarqui-Mamani, Carolina B, Tautu, Oana-Florentina, Taylor, Anne, Theobald, Holger, Theodoridis, Xenophon, Thijs, Lutgarde, Thuesen, Betina H, Tjonneland, Anne, Tolonen, Hanna K, Tolstrup, Janne S, Topbas, Murat, Topór-Madry, Roman, Tormo, María José, Torrent, Matie, Traissac, Pierre, Trichopoulos, Dimitrio, Trichopoulou, Antonia, Trinh, Oanh T H, Trivedi, Atul, Tshepo, Lechaba, Tulloch-Reid, Marshall K, Tullu, Fikru, Tuomainen, Tomi-Pekka, Tuomilehto, Jaakko, Turley, Maria L, Tynelius, Per, Tzourio, Christophe, Ueda, Peter, Ugel, Eunice E, Ulmer, Hanno, Uusitalo, Hannu M T, Valdivia, Gonzalo, Valvi, Damaskini, van der Schouw, Yvonne T, Van Herck, Koen, Van Minh, Hoang, van Rossem, Lenie, Van Schoor, Natasja M, van Valkengoed, Irene G M, Vanderschueren, Dirk, Vanuzzo, Diego, Vatten, Lar, Vega, Toma, Velasquez-Melendez, Gustavo, Veronesi, Giovanni, Monique Verschuren, W M, Verstraeten, Roosmarijn, Victora, Cesar G, Viet, Lucie, Viikari-Juntura, Eira, Vineis, Paolo, Vioque, Jesu, Virtanen, Jyrki K, Visvikis-Siest, Sophie, Viswanathan, Bharathi, Vlasoff, Tiina, Vollenweider, Peter, Voutilainen, Sari, Wade, Alisha N, Wagner, Aline, Walton, Janette, Wan Bebakar, Wan Mohamad, Wan Mohamud, Wan Nazaimoon, Wanderley, Rildo S, Wang, Ming-Dong, Wang, Qian, Wang, Ya Xing, Wang, Ying-Wei, Wannamethee, S Goya, Wareham, Nichola, Wedderkopp, Niel, Weerasekera, Deepa, Whincup, Peter H, Widhalm, Kurt, Widyahening, Indah S, Wiecek, Andrzej, Wijga, Alet H, Wilks, Rainford J, Willeit, Johann, Willeit, Peter, Williams, Emmanuel A, Wilsgaard, Tom, Wojtyniak, Bogdan, Wong-McClure, Roy A, Wong, Justin Y Y, Wong, Tien Yin, Woo, Jean, Giwercman Wu, Aleksander, Wu, Frederick C, Wu, Shouling, Xu, Haiquan, Yan, Weili, Yang, Xiaoguang, Ye, Xingwang, Yiallouros, Panayiotis K, Yoshihara, Akihiro, Younger-Coleman, Novie O, Yusoff, Ahmad Faudzi, Zainuddin, Ahmad Ali, Zambon, Sabina, Zampelas, Antoni, Zdrojewski, Tomasz, Zeng, Yi, Zhao, Dong, Zhao, Wenhua, Zheng, Wei, Zheng, Yingfeng, Zhu, Dan, Zhussupov, Baurzhan, Zimmermann, Esther, Cisneros, Julio Zuñiga, The State Key Laboratory of Cell Biology [Shanghai, China] (CAS Center for Excellence in Molecular Cell Science), Shanghai Institute of Biochemistry and Cell Biology [Shanghai, China]-University of Chinese Academy of Sciences [Shanghai, China], Imperial College London, University of Kentucky, Middlesex University, Cleveland Clinic, Universidad Peruana Cayetano Heredia (UPCH), Brandeis University, Mulago Hospital [Kampala, Ouganda], Department of Epidemiology and Public Health, Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO), World Health Organisation (WHO), Al-Quds University, Discipline of Medicine, University of South Australia [Adelaide], Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán - National Institute of Medical Science and Nutrition Salvador Zubiran [Mexico], Leibniz Institute for Prevention Research and Epidemiology - BIPS, Leibniz Association, Centre for Industrial Management, Catholic University of Leuven - Katholieke Universiteit Leuven (KU Leuven), Epidémiologie des maladies chroniques : impact des interactions gène environnement sur la santé des populations, Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille, Droit et Santé, Institute of Preventive Medicine, Copenhagen University Hospitals, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Dept. Atherosclerose, University of Iceland [Reykjavik], Institute for Biotechnology and Bioengineering (IBB), Technical University of Lisbon, Medical University of Łódź (MUL), Department of Preventive Medicine and Public Health, Universidad Autónoma de Madrid (UAM), Faculté de Médecine de Tunis, Université de Tunis El Manar (UTM), Sunder Lal Jain Hospital, Ufa Eye Research Institute [Bashkortostan], National Institute of Public Health, Department of Epidemiology, Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke (DifE), Leibniz Association-Leibniz Association, CHU Toulouse [Toulouse], Institute of Social and Preventive Medicine, Lausanne university hospital, Division of Clinical Epidemiology and Aging Research, German Cancer Research Center - Deutsches Krebsforschungszentrum [Heidelberg] (DKFZ), Department of Medical Sciences [Turin, Italy] (DMS), Università degli studi di Torino = University of Turin (UNITO), ASU - School for Engineering of Matter, Transport and Energy, Arizona State University [Tempe] (ASU), Universidade do Porto = University of Porto, University of Oxford [Oxford], Cancer & Radiation Epidemiology Unit, Gertner Institute, Chaim Sheba Medical Center, Consorcio de Investigación Biomédica en Red especializado en Epidemiología y Salud Pública (CIBERESP), Los Centros de Investigación Biomédica en Red (CIBER), 2nd Department of Internal Medicine, Molecular Medicine, Catholic University of Leuven - Katholieke Universiteit Leuven (KU Leuven)-IRC KULAK, Department of Public Health, State University of Ghent, MRC Lifecourse Epidemiology Unit [Southampton, UK], University of Southampton, Réseau International des Instituts Pasteur (RIIP), Institute of Epidemiology [Neuherberg] (EPI), German Research Center for Environmental Health - Helmholtz Center München (GmbH), Sahlgrenska University Hospital [Gothenburg], Institute of Metabolic Science, MRC, Institut National de Nutrition et de Technologie Alimentaire (INNTA), University of Huddersfield, IMIM-Hospital del Mar, Generalitat de Catalunya, Medstar Research Institute, Queen's University [Belfast] (QUB), Medical Research Council, Applied Sciences, National Research Institute on Food and Nutrition, Epidémiologie et analyses en santé publique : risques, maladies chroniques et handicaps (LEASP), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM), Infectious diseases division, Department of internal medicine, Washington University in Saint Louis (WUSTL), Innsbruck Medical University [Austria] (IMU), Department of Epidemiology [Rotterdam], Erasmus University Medical Center [Rotterdam] (Erasmus MC), Laboratoire d'Etude des Mammifères Marins (LEMM), Océanopolis [Brest], Faculté de Médecine Henri Warembourg - Université de Lille, Institute of Sport Science and Clinical Biomechanics, University of Southern Denmark (SDU), Icelandic Heart Association, Heart Preventive Clinic and Research Institute, Centro Investig Quim Aplicada, Coahuila, Mexico, Centro Investigacion en Quimica Aplicada, Coahuila, Mexico, University of Geneva [Switzerland], Department of Civil Engineering [Hamirpur], National Institute of Technology [Hamirpur], Health Services Research Unit, Danish Cancer Society, Institute of Cancer Epidemiology, London School of Hygiene and Tropical Medicine (LSHTM), University College of London [London] (UCL), The Georges Institute for International Health, The University of Sydney, School of Information Technology, Deakin University Waurn Ponds, Faculté de Médecine, Université Djilali Liabès [Sidi-Bel-Abbès], Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), CIBER de Epidemiología y Salud Pública (CIBERESP), VU University Medical Center [Amsterdam], Universiteit Gent = Ghent University [Belgium] (UGENT), Faculty of Agricultural and Food Science, American University of Beirut [Beyrouth] (AUB), Åbo Akademi University [Turku], Department of Public Health Sciences, Karolinska Institutet [Stockholm], Great Lakes Institute for Environmental Research, University of Windsor [Ca], Universität Heidelberg [Heidelberg], Research Center for Prevention and Health, University of Ljubljana, Division of Cancer Epidemiology, University of Crete School of medicine, School of Public Health and Clinical Nutrition, University of Eastern Finland, Institute of Epidemiology and Social Medicine, Westfälische Wilhelms-Universität Münster = University of Münster (WWU), Research Institute of Child Nutrition Dortmund, Rheinische Friedrich-Wilhelms-Universität Bonn, Cancer Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge [UK] (CAM), Department of Oncology, University of Tampere Medical School, University of Tampere, Wageningen University and Research [Wageningen] (WUR), Centre for Environmental Health, National Institue of Public Health, School of Public Health, The University of Hong Kong (HKU), Tehran University of Medical Sciences, Istituto Nazionale di Ricerca per gli Alimenti e la Nutrizione (INRAN), INRAN, National University of Singapore (NUS), Faculty of Medicine and Life Sciences [Tampere], University of Tampere [Finland], Centre Européen de Réalité Virtuelle (CERV), École Nationale d'Ingénieurs de Brest (ENIB), Uppsala Universitet [Uppsala], Department of Public Health and Community Medicine, University of Gothenburg (GU), Institute of Earthquake Science, CEA, Beijing, CEA, Beijing, University of Porto Medical School, Laboratoire de Chimie Physique D'Orsay (LCPO), Université Paris-Sud - Paris 11 (UP11)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Aging Program, National research council, Padua, Italy, Baker IDI Heart and Diabetes Institute, Institute of Internal Medicine, Russian Academy of Medical Sciences, Department of Nutrition and Dietetics, Harokopio University, Emory University [Atlanta, GA], Départment of Biotechnology, Faculty of Science, University of Oran Es-Senia [Oran] | Université d'Oran Es-Senia [Oran], Institut National de la Santé et de la Recherche Médicale (INSERM), University of Tartu, Department of Community, Université Ain Shams-Faculty of Medicine-Environmental and Occupational Medicine, Pécsi Tudemányegyetem, Department of Community, Environmental and Occupational Medicine, Université Ain Shams, Research Centre in Physical Activity, Health and Leisure, Nutrition and Metabolism Section, International Agency for Research on Cancer, Bushehr University of Medical Sciences, Institute of Epidemiology and Medical Biometry [Ulm, Allemagne], Universität Ulm - Ulm University [Ulm, Allemagne], Università degli studi di Palermo - University of Palermo, MRc Environmental Epidemiology Unit, Department of Cardiology and Department of Clinical Epidemiology, Aarhus University Hospital, Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Department of Epidemiology and Population Studies, Jagiellonian University, Uniwersytet Jagielloński w Krakowie = Jagiellonian University (UJ), Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute – ISPO, Social Robotics Laboratory, University of Freiburg, Freiburg im Breisgau, Department of Ophthalmology, Universitätsklinikum Mannheim, Medizinische Fakultät Mannheim der Universität Heidelberg, University of Bari Aldo Moro (UNIBA), Department of Cardiology, Eastbourne General Hospital, Julius Center for Health Sciences and Primary Care, University Medical Center [Utrecht], Laboratoire d'Innovation pour les Technologies des Energies Nouvelles et les nanomatériaux (LITEN), Institut National de L'Energie Solaire (INES), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), King‘s College London, Public Health Sciences, University of Edinburgh, Movement Disorders and Tourette Centre, Genetica medicala, Victor Babeş University of Medicine and Pharmacy (UMFT), Andrology Unit, United Laboratories of Tartu University Clinics, Tampere University Hospital, Department of Hygiene and Epidemiology, Dept of Epidemiology and Public Health, Department of Epidemiology and Biostatistics, Imperial College London-School of public health, The University of Hong Kong (HKU)-The University of Hong Kong (HKU), Department of Emergency and Cardiovascular Medicine, Sahlgrenska Academy, Institut de Veille Sanitaire (INVS), Department of Epidemiology, Murcia Regional Health Council, Murcia, Spain, parent, Department of Chronic Disease Prevention, National Institute for Health and Welfare [Helsinki], University of São Paulo (USP), Institut de Recherche pour le Développement (IRD [France-Sud]), Institute for plasma research, Institute for Plasma Research, Department of Biosciences and Nutrition, Department of Reproductive Endocrinology, Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam UMC - Academic medical center, Central Hospital and Faculty of medicine and biomedical sciences university, University of Yaoundé [Cameroun], Department of Clinical Sciences, Lund University [Lund]-Lund University Diabetes Centre, School of Computing [Leeds], University of Leeds, Copenhagen University Hospital, Neuroépidémiologie, Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Maastricht University [Maastricht], Interactions Gène-Environnement en Physiopathologie Cardio-Vasculaire (IGE-PCV), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Applied Food Science, Department of Surgical and Perioperative Sciences, Urology and Andrology, Umeå University, University of Amsterdam, Dept. of Social Medecine, Department of Medical Sciences and Uppsala Clinical Research Center, Uppsala University Hospital, Africa Centre for Health and Population Studies, University of KwaZulu-Natal [Durban, Afrique du Sud] (UKZN)-Medical Research Council of South Africa, Center for Family and Community Medicine, Department of Neurobiology, Care Sciences and Society, Department of Cardiovascular Sciences [Leuven], Cancer Epidemiology Institute, Department of Epidemiology and Health Promotion (MONICA Data Centre), National Public Health Institute, Nutrition et Alimentation des Populations aux Suds (NutriPass), Université Montpellier 1 (UM1)-Institut de Recherche pour le Développement (IRD)-Université Montpellier 2 - Sciences et Techniques (UM2)-Université de Montpellier (UM)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Havard School of Public Health, Dept of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School [Athens], University of Kuopio, Tampere University, University Medical Centre Utrecht, Department of Social Medicine, Amsterdam, Center for Metabolic Bone Diseases, Catholic University of Leuven, Norwegian University of Science and Technology [Trondheim] (NTNU), Norwegian University of Science and Technology (NTNU), Universidad Miguel Hernández [Elche] (UMH), Institute of Public Health and Clinical Nutrition [Kuopio, Finland], Department of Internal Medicine, Centre Hospitalier Universitaire Vaudois [Lausanne] (CHUV), Fédération de Médecine Translationnelle de Strasbourg (FMTS), Université de Strasbourg (UNISTRA), Laboratoire Chrono-environnement - CNRS - UBFC (UMR 6249) (LCE), Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Division of Community Health Sciences, St George's University of London, Medizinische Universität Wien = Medical University of Vienna, Medical University of Silesia (SUM), National Institute for Public Health and the Environment [Bilthoven] (RIVM), University of Innsbruck, National Institute of Hygiene Warsaw, Johns Hopkins University School of Medicine [Baltimore], Food Science and Technology, Beijing Forestry University, College of Automation Engineering, Nanjing University of Aeronautics and Astronautics (CAE-NUAA), NUAA, Chinese Center for Disease Control and Prevention, Department of Applied Mathematics, School of Science, Northwestern Polytechnical University, Xi’an, Shaanxi 710072, Siemens Corporate Research, Siemens AG [Munich], Franche-Comté Électronique Mécanique, Thermique et Optique - Sciences et Technologies (UMR 6174) (FEMTO-ST), Université de Technologie de Belfort-Montbeliard (UTBM)-Ecole Nationale Supérieure de Mécanique et des Microtechniques (ENSMM)-Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), This work was supported by the Wellcome Trust [101506/Z/13/Z]., NCD Risk Factor Collaboration (NCD-RisC). We thank WHO country and regional offices and the World Heart Federation for support in data identification and access., Universidad Autonoma de Madrid (UAM), University of Turin, Universidade do Porto, Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, Université Lille 2 - Faculté de Médecine, Westfälische Wilhelms-Universität Münster (WWU), Centre National de la Recherche Scientifique (CNRS)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), University of KwaZulu-Natal (UKZN)-Medical Research Council of South Africa, Institut de Recherche pour le Développement (IRD)-Université Montpellier 1 (UM1)-Université Montpellier 2 - Sciences et Techniques (UM2)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Université de Montpellier (UM), Université de Technologie de Belfort-Montbeliard (UTBM)-Ecole Nationale Supérieure de Mécanique et des Microtechniques (ENSMM)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre National de la Recherche Scientifique (CNRS), Lund University Diabetes Centre-Lund University [Lund], Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Medical University of Silesia, Katowice, Apollo - University of Cambridge Repository, University of Kentucky (UK), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Lausanne University Hospital, University of Oxford, Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM), Innsbruck Medical University = Medizinische Universität Innsbruck (IMU), Université de Genève = University of Geneva (UNIGE), Deakin University [Waurn Ponds], Universiteit Gent = Ghent University (UGENT), Universität Heidelberg [Heidelberg] = Heidelberg University, Università degli studi di Bari Aldo Moro = University of Bari Aldo Moro (UNIBA), Universidade de São Paulo = University of São Paulo (USP), Lund University [Lund], Laboratoire Chrono-environnement (UMR 6249) (LCE), Leopold Franzens Universität Innsbruck - University of Innsbruck, National Institute of Public Health - National Institute of Hygiene [Poland], Yiallouros, Panayiotis K. [0000-0002-8339-9285], Giampaoli, Simona [0000-0002-6679-1488], Moschonis, George [0000-0003-3009-6675], Papandreou, Dimitrios [0000-0002-4923-484X], Stathopoulou, Maria G. [0000-0003-4376-2083], Stergiou, George S. [0000-0002-6132-0038], Trichopoulou, Antonia [0000-0002-7204-6396], Valvi, Damaskini [0000-0003-4633-229X], Chen, Z, Woodward, M, Key, T, and Smith, M
Subjects: systolic blood pressure, Settore MED/09 - Medicina Interna, blood pressure measurement, HEALTH EXAMINATION SURVEYS, Blood Pressure, Hypertension, Population Health, Global Health, Non-communicable Disease, Epidemiology, [SDV]Life Sciences [q-bio], global health, South Asia, purl.org/pe-repo/ocde/ford#3.03.09 [https], kohonnut verenpaine, Medicine and Health Sciences, middle income country, measurement method, skin and connective tissue diseases, VDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Kardiologi: 771, Public, Environmental & Occupational Health, adult, Population health, public health, blood pressure regulation, Public Health, Global Health, Social Medicine and Epidemiology, Non-communicable disease, kansainvälinen vertailu, health survey, aged, female, priority journal, Blood pressure, mean arterial pressure, GLOBAL TRENDS, SODIUM-INTAKE, Life Sciences & Biomedicine, survey design, hypertension, prevalence, Global health, UNITED-STATES, URBAN COMMUNITIES, Article, SECULAR TRENDS, Middle East, Central Asia, male, disease prevalence, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, kansanterveys, blood, SYSTEMATIC ANALYSIS, human, verenpainetauti, non-communicable disease, Science & Technology, Pacific Ocean, high income country, diastolic blood pressure, Pacific Rim, Blood Pressure - Epidemiology - Population, North Africa, major clinical study, HYPERTENSION PREVALENCE, verenpaine, Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi, ARTERIAL-HYPERTENSION, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, POTASSIUM INTAKE, sense organs, trend analysis, trend study, population research, population health, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, low income country
Abstract: Background: Change in the prevalence of raised blood pressure could be due to both shifts in the entire distribution of blood pressure (representing the combined effects of public health interventions and secular trends) and changes in its high-blood-pressure tail (representing successful clinical interventions to control blood pressure in the hypertensive population). Our aim was to quantify the contributions of these two phenomena to the worldwide trends in the prevalence of raised blood pressure. Methods: We pooled 1018 population-based studies with blood pressure measurements on 88.6 million participants from 1985 to 2016. We first calculated mean systolic blood pressure (SBP), mean diastolic blood pressure (DBP) and prevalence of raised blood pressure by sex and 10-year age group from 20-29 years to 70-79 years in each study, taking into account complex survey design and survey sample weights, where relevant. We used a linear mixed effect model to quantify the association between (probit-transformed) prevalence of raised blood pressure and age-group-and sex-specific mean blood pressure. We calculated the contributions of change in mean SBP and DBP, and of change in the prevalence-mean association, to the change in prevalence of raised blood pressure. Results: In 2005-16, at the same level of population mean SBP and DBP, men and women in South Asia and in Central Asia, the Middle East and North Africa would have the highest prevalence of raised blood pressure, and men and women in the high-income Asia Pacific and high-income Western regions would have the lowest. In most region-sex-age groups where the prevalence of raised blood pressure declined, one half or more of the decline was due to the decline in mean blood pressure. Where prevalence of raised blood pressure has increased, the change was entirely driven by increasing mean blood pressure, offset partly by the change in the prevalence-mean association. Conclusions: Change in mean blood pressure is the main driver of the worldwide change in the prevalence of raised blood pressure, but change in the high-blood-pressure tail of the distribution has also contributed to the change in prevalence, especially in older age groups., This work was supported by the Wellcome Trust [101506/Z/13/Z].
Published: 2018
Full Text: View/download PDF

6. Genetic Characterization of the Fish Piaractus brachypomus by Microsatellites Derived from Transcriptome Sequencing

Author: Natália J. Mendes, Diogo Teruo Hashimoto, Vito A. Mastrochirico-Filho, Fábio Porto-Foresti, Manuel Vera, Milene Elissa Hata, Raquel B. Ariede, Milena V. Freitas, Paulo Henrique Jorge, Universidade Estadual Paulista (Unesp), Univ Santiago Compostela, Universidade de Santiago de Compostela. Centro de Investigación en Medicina Molecular e Enfermidades Crónicas, and Universidade de Santiago de Compostela. Departamento de Zooloxía, Xenética e Antropoloxía Física
Subjects: 0106 biological sciences, 0301 basic medicine, lcsh:QH426-470, Fish farming, Zoology, Biology, 010603 evolutionary biology, 01 natural sciences, 03 medical and health sciences, Genetic variation, Genetics, genetic structure, Genetic variability, Genetics (clinical), Original Research, Piaractus brachypomus, Genetic diversity, biology.organism_classification, lcsh:Genetics, 030104 developmental biology, aquaculture, Genetic marker, NGS, Genetic structure, Molecular Medicine, Microsatellite, Pirapitinga, Serrasalmidae
Abstract: Made available in DSpace on 2018-11-26T17:48:18Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-02-22 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) PROPE/UNESP The pirapitinga, Piaractus brachypomus (Characiformes, Serrasalmidae), is a fish from the Amazon basin and is considered to be one of the main native species used in aquaculture production in South America. The objectives of this study were: (1) to perform liver transcriptome sequencing of pirapitinga through NGS and then validate a set of microsatellite markers for this species; and (2) to use polymorphic microsatellites for analysis of genetic variability in farmed stocks. The transcriptome sequencing was carried out through the Roche/454 technology, which resulted in 3,696 non-redundant contigs. Of this total, 2,568 contigs had similarity in the non-redundant (nr) protein database (Genbank) and 2,075 sequences were characterized in the categories of Gene Ontology (GO). After the validation process of 30 microsatellite loci, eight markers showed polymorphism. The analysis of these polymorphic markers in farmed stocks revealed that fish farms from North Brazil had a higher genetic diversity than fish farms from Southeast Brazil. AMOVA demonstrated that the highest proportion of variation was presented within the populations. However, when comparing different groups (1: Wild; 2: North fish farms; 3: Southeast fish farms), a considerable variation between the groups was observed. The F-ST values showed the occurrence of genetic structure among the broodstocks from different regions of Brazil. The transcriptome sequencing in pirapitinga provided important genetic resources for biological studies in this non-model species, and microsatellite data can be used as the framework for the genetic management of breeding stocks in Brazil, which might provide a basis for a genetic pre-breeding programme. Sao Paulo State Univ, Univ Estadual Paulista Julio Mesquita Filho, Aquaculture Ctr, Jaboticabal, Brazil Univ Santiago Compostela, Vet Fac, Lugo, Spain Sao Paulo State Univ, Sch Sci, Bauru, Brazil Sao Paulo State Univ, Univ Estadual Paulista Julio Mesquita Filho, Aquaculture Ctr, Jaboticabal, Brazil Sao Paulo State Univ, Sch Sci, Bauru, Brazil FAPESP: 2014/03772-7 FAPESP: 2014/05732-2 CNPq: 446779/2014-8 CNPq: 305916/2015-7
Published: 2018

Catalog

Books, media, physical & digital resources

See catalog results

Searchworks

Select search scope, currently: Articles

Catalog

books, media & more in Jio Institute collections

Articles

journal articles & other e-resources

Refine your results

6 results on '"Univ Santiago Compostela"'

1. HYDROALCOHOLIC SYSTEM FOR NAIL TREATMENT

2. Integrating digital pathology with transcriptomic and epigenomic tools for predicting metastatic uterine tumor aggressiveness

3. Obesity- and gender-dependent role of endogenous somatostatin and cortistatin in the regulation of endocrine and metabolic homeostasis in mice

4. Levosimendan beyond inotropy and acute heart failure: Evidence of pleiotropic effects on the heart and other organs: An expert panel position paper

5. Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: A pooled analysis of 1018 population-based measurement studies with 88.6 million participants

6. Genetic Characterization of the Fish Piaractus brachypomus by Microsatellites Derived from Transcriptome Sequencing

Catalog

Searchworks

Select search scope, currently: Articles Catalog books, media & more in Jio Institute collections Articles journal articles & other e-resources

Search

Search Constraints

Refine your results

Search Limiters

Topic

Publication Year Range

Language

Database

Publisher

6 results on '"Univ Santiago Compostela"'

Search Results

Catalog

Select search scope, currently: Articles

Catalog

books, media & more in Jio Institute collections

Articles

journal articles & other e-resources