38 results on '"Univ Paris VI"'
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2. AGN Outflow Shocks on Bonnor–Ebert Spheres
- Author
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Bieri, Rebekka [Institut d’Astrophysique de Paris, UMR 7095, CNRS, UPMC Univ. Paris VI, 98 bis Boulevard Arago, F-75014 Paris (France)]
- Published
- 2017
- Full Text
- View/download PDF
3. Studies of X(3872) and psi(2S) production in p(p)over-bar collisions at 1.96 TeV
- Author
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Abazov, V. M., Abbott, B., Acharya, B. S., Adams, M., Adams, T., Agnew, J. P., Alexeev, G. D., Alkhazov, G., Alton, A., Askew, A., Atkins, S., Augsten, K., Aushev, V, Aushev, Y., Avila, C., Badaud, F., Bagby, L., Baldin, B., Bandurin, D., Banerjee, S., Barberis, E., Baringer, P., Bartlett, J. F., Bassler, U., Bazterra, V, Bean, A., Begalli, M., Bellantoni, L., Beri, S. B., Bernardi, G., Bernhard, R., Bertram, I, Besancon, M., Beuselinck, R., Bhat, P. C., Bhatia, S., Bhatnagar, V, Blazey, G., Blessing, S., Bloom, K., Boehnlein, A., Boline, D., Boos, E. E., Borissov, G., Borysova, M., Brandt, A., Brandt, O., Brochmann, M., Brock, R., Bross, A., Brown, D., Bu, X. B., Buehler, M., Buescher, V, Bunichev, V, Burdin, S., Buszello, C. P., Camacho-Perez, E., Casey, B. C. K., Castilla-Valdez, H., Caughron, S., Chakrabarti, S., Chan, K. M., Chandra, A., Chapon, E., Chen, G., Cho, S. W., Choi, S., Choudhary, B., Cihangir, S., Claes, D., Clutter, J., Cooke, M., Cooper, W. E., Corcoran, M., Couderc, F., Cousinou, M-C, Cuth, J., Cutts, D., Das, A., Davies, G., Jong, S. J. de, De La Cruz-Burelo, E., Deliot, F., Demina, R., Denisov, D., Denisov, S. P., Desai, S., Deterre, C., DeVaughan, K., Diehl, H. T., Diesburg, M., Ding, P. F., Dominguez, A., Drutskoy, A., Dubey, A., Dudko, L., Duperrin, A., Dutt, S., Eads, M., Edmunds, D., Ellison, J., Elvira, V. D., Enari, Y., Evans, H., Evdokimov, A., Evdokimov, V. N., Faure, A., Feng, L., Ferbel, T., Fiedler, F., Filthaut, F., Fisher, W., Fisk, H. E., Fortner, M., Fox, H., Franc, J., Fuess, S., Garbincius, P. H., Garcia-Bellido, A., Garcia-Gonzalez, J. A., Gavrilov, V, Geng, W., Gerber, C. E., Gershtein, Y., Ginther, G., Gogota, O., Golovanov, G., Grannis, P. D., Greder, S., Greenlee, H., Grenier, G., Gris, Ph, Grivaz, J-F, Grohsjean, A., Grunendahl, S., Grunewald, M. W., Guillemin, T., Gutierrez, G., Gutierrez, P., Haley, J., Han, L., Harder, K., Harel, A., Hauptman, J. M., Hays, J., Head, T., Hebbeker, T., Hedin, D., Hegab, H., Heinson, A. P., Heintz, U., Hensel, C., Heredia-De La Cruz, I, Herner, K., Hesketh, G., Hildreth, M. D., Hirosky, R., Hoang, T., Hobbs, J. D., Hoeneisen, B., Hogan, J., Hohlfeld, M., Holzbauer, J. L., Howley, I, Hubacek, Z., Hynek, V, Iashvili, I., Ilchenko, Y., Illingworth, R., Ito, A. S., Jabeen, S., Jaffre, M., Jayasinghe, A., Jeong, M. S., Jesik, R., Jiang, P., Johns, K., Johnson, E., Johnson, M., Jonckheere, A., Jonsson, P., Joshi, J., Jung, A. W., Juste, A., Kajfasz, E., Karmanov, D., Katsanos, I, Kaur, M., Kehoe, R., Kermiche, S., Khalatyan, N., Khanov, A., Kharchilava, A., Kharzheev, Y. N., Kiselevich, I, Kohli, J. M., Kozelov, A., Kraus, J., Kumar, A., Kupco, A., Kuzmin, V. A., Lammers, S., Lebrun, P., Lee, H. S., Lee, S. W., Lee, W. M., Lei, X., Lellouch, J., Li, D., Li, H., Li, L., Li, Q. Z., Lim, J. K., Lincoln, D., Linnemann, J., Lipaev, V. V., Lipton, R., Liu, H., Liu, Y., Lobodenko, A., Lokajicek, M., Sa, R. Lopes de, Luna-Garcia, R., Lyon, A. L., Maciel, A. K. A., Madar, R., Magana-Villalba, R., Malik, S., Malyshev, V. L., Mansour, J., Martinez-Ortega, J., McCarthy, R., McGivern, C. L., Meijer, M. M., Melnitchouk, A., Menezes, D., Mercadante, P. G., Merkin, M., Meyer, A., Meyer, J., Miconi, F., Mondal, N. K., Mulhearn, M., Nagy, E., Narain, M., Nayyar, R., Neal, H. A., Negret, J. P., Neustroev, P., Nguyen, H. T., Nunnemann, T., Orduna, J., Osman, N., Pal, A., Parashar, N., Parihar, V, Park, S. K., Partridge, R., Parua, N., Patwa, A., Penning, B., Perfilov, M., Peters, Y., Petridis, K., Petrillo, G., Petroff, P., Pleier, M-A, Podstavkov, V. M., Popov, A., Prewitt, M., Price, D., Prokopenko, N., Qian, J., Quadt, A., Quinn, B., Ratoff, P. N., Razumov, I, Ripp-Baudot, I, Rizatdinova, F., Rominsky, M., Ross, A., Royon, C., Rubinov, P., Ruchti, R., Sajot, G., Sanchez-Hernandez, A., Sanders, M. P., Santos, A. S. [UNESP], Savage, G., Savitskyi, M., Sawyer, L., Scanlon, T., Schamberger, R. D., Scheglov, Y., Schellman, H., Schott, M., Schwanenberger, C., Schwienhorst, R., Sekaric, J., Severini, H., Shabalina, E., Shary, V, Shaw, S., Shchukin, A. A., Shkola, O., Simak, V, Skubic, P., Slattery, P., Snow, G. R., Snow, J., Snyder, S., Soldner-Rembold, S., Sonnenschein, L., Soustruznik, K., Stark, J., Stefaniuk, N., Stoyanova, D. A., Strauss, M., Suter, L., Svoisky, P., Titov, M., Tokmenin, V. V., Tsai, Y-T, Tsybychev, D., Tuchming, B., Tully, C., Uvarov, L., Uvarov, S., Uzunyan, S., Van Kooten, R., van Leeuwen, W. M., Varelas, N., Varnes, E. W., Vasilyev, I. A., Verkheev, A. Y., Vertogradov, L. S., Verzocchi, M., Vesterinen, M., Vilanova, D., Vokac, P., Wahl, H. D., Wang, C., Wang, M. H. L. S., Warchol, J., Watts, G., Wayne, M., Weichert, J., Welty-Rieger, L., Williams, M. R. J., Wilson, G. W., Wobisch, M., Wood, D. R., Wyatt, T. R., Xie, Y., Yamada, R., Yang, S., Yasuda, T., Yatsunenko, Y. A., Ye, W., Ye, Z., Yin, H., Yip, K., Youn, S. W., Yu, J. M., Zennamo, J., Zhao, T. G., Zhou, B., Zhu, J., Zielinski, M., Zieminska, D., Zivkovic, L., D0 Collaboration, Ctr Brasileiro Pesquisas Fis, Universidade do Estado do Rio de Janeiro (UERJ), Universidade Federal do ABC (UFABC), Univ Sci & Technol China, Univ Los Andes, Charles Univ Prague, Czech Tech Univ, Acad Sci Czech Republ, Univ San Francisco Quito, Univ Blaise Pascal, Univ Joseph Fourier Grenoble 1, Aix Marseille Univ, Univ Paris Sud, Univ Paris VI, Univ Paris VII, Univ Paris Saclay, Univ Strasbourg, Univ Lyon 1, Univ Lyon, Rhein Westfal TH Aachen, Univ Freiburg, Georg August Univ Gottingen, Johannes Gutenberg Univ Mainz, Ludwig Maximilians Univ Munchen, Panjab Univ, Delhi Univ, Tata Inst Fundamental Res, Univ Coll Dublin, Korea Univ, CINVESTAV, Nikhef, Radboud Univ Nijmegen, Joint Inst Nucl Res, Inst Theoret & Expt Phys, Moscow MV Lomonosov State Univ, Inst High Energy Phys, Petersburg Nucl Phys Inst, Inst Catalana Recerca & Estudis Avancats ICREA, Inst Fis Altes Energies IFAE, Uppsala Univ, Taras Shevchenko Natl Univ Kyiv, Univ Lancaster, Imperial Coll London, Univ Manchester, Univ Arizona, Univ Calif Riverside, Florida State Univ, Fermilab Natl Accelerator Lab, Univ Illinois, Northern Illinois Univ, Northwestern Univ, Indiana Univ, Purdue Univ Calumet, Univ Notre Dame, Iowa State Univ, Univ Kansas, Louisiana Tech Univ, Northeastern Univ, Univ Michigan, Michigan State Univ, Univ Mississippi, Univ Nebraska, Rutgers State Univ, Princeton Univ, SUNY Buffalo, Univ Rochester, SUNY Stony Brook, Brookhaven Natl Lab, Langston Univ, Univ Oklahoma, Oklahoma State Univ, Oregon State Univ, Brown Univ, Univ Texas Arlington, Southern Methodist Univ, Rice Univ, Univ Virginia, Univ Washington, Augustana Univ, Kiev Inst Nucl Res KINR, Univ Liverpool, US DOE, DESY, Russian Acad Sci, CONACyT, UCL, Univ Maryland, Purdue Univ, Ctr Invest Comp IPN, Karlsruher Inst Technol KIT, SLAC, Universidade Estadual Paulista (Unesp), CERN, and Inst Phys
- Abstract
Made available in DSpace on 2021-06-25T11:22:30Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-10-13 Fermi Research Alliance, LLC (FRA) Department of Energy (United States of America) National Science Foundation (United States of America) Alternative Energies and Atomic Energy Commission (France) National Center for Scientific Research/National Institute of Nuclear and Particle Physics (France) Ministry of Education and Science of the Russian Federation (Russia) National Research Center Kurchatov Institute of the Russian Federation (Russia) Russian Foundation for Basic Research (Russia) National Council for the Development of Science and Technology (Brazil) Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ) Department of Atomic Energy (India) Department of Science and Technology (India) Administrative Department of Science, Technology and Innovation (Colombia) National Council of Science and Technology (Mexico) National Research Foundation of Korea (Korea) Foundation for Fundamental Research on Matter (The Netherlands) Science and Technology Facilities Council (United Kingdom) Royal Society (United Kingdom) Ministry of Education, Youth and Sports (Czech Republic) Bundesministerium fur Bildung und Forschung (Federal Ministry of Education and Research) (Germany) Deutsche Forschungsgemeinschaft (German Research Foundation) (Germany) Science Foundation Ireland (Ireland) Swedish Research Council (Sweden) China Academy of Sciences (China) National Natural Science Foundation of China (China) Ministry of Education and Science of Ukraine (Ukraine) We present various properties of the production of the X(3872) and psi(2S) states based on 10.4 fb(-1) collected by the D0 experiment in Tevatron p (p) over bar collisions at root s = 1.96 TeV. For both states, we measure the nonprompt fraction f(NP) of the inclusive production rate due to decays of b-flavored hadrons. We find the f(NP) values systematically below those obtained at the LHC. The f(NP) fraction for psi(2S) increases with transverse momentum, whereas for the X(3872) it is constant within large uncertainties, in agreement with the LHC results. The ratio of prompt to nonprompt psi(2S) production, ( 1 - f(NP))/f(NP), decreases only slightly going from the Tevatron to the LHC, but for the X(3872), this ratio decreases by a factor of about 3. We test the soft-pion signature of the X(3872) modeled as a weakly bound charm-meson pair by studying the production of the X(3872) as a function of the kinetic energy of the X(3872) and the pion in the X(3872)pi center-of-mass frame. For a subsample consistent with prompt production, the results are incompatible with a strong enhancement in the production of the X(3872) at the small kinetic energy of the X(3872) and the pi in the X(3872)pi center-of-mass frame expected for the X + soft-pion production mechanism. For events consistent with being due to decays of b hadrons, there is no significant evidence for the soft-pion effect, but its presence at the level expected for the binding energy of 0.17 MeV and the momentum scale Lambda = M(pi) is not ruled out. Ctr Brasileiro Pesquisas Fis, LAFEX, BR-22290 Rio De Janeiro, RJ, Brazil Univ Estado Rio de Janeiro, BR-20550 Rio De Janeiro, RJ, Brazil Univ Fed ABC, BR-09210 Santo Andre, SP, Brazil Univ Sci & Technol China, Hefei 230026, Peoples R China Univ Los Andes, Bogota 111711, Colombia Charles Univ Prague, Fac Math & Phys, Ctr Particle Phys, Prague 11636 1, Czech Republic Czech Tech Univ, Prague 11636 6, Czech Republic Acad Sci Czech Republ, Inst Phys, Prague 18221, Czech Republic Univ San Francisco Quito, Quito 170157, Ecuador Univ Blaise Pascal, LPC, IN2P3, CNRS, F-63178 Aubiere, France Univ Joseph Fourier Grenoble 1, Inst Natl Polytech Grenoble, IN2P3, CNRS,LPSC, F-38026 Grenoble, France Aix Marseille Univ, IN2P3, CNRS, CPPM, F-13288 Marseille 09, France Univ Paris Sud, Univ Paris Saclay, IN2P3, CNRS,LAL, F-91898 Orsay, France Univ Paris VI, LPNHE, F-75005 Paris, France Univ Paris VII, CNRS, IN2P3, F-75005 Paris, France Univ Paris Saclay, CEA, IRFU, F-91191 Gif Sur Yvette, France Univ Strasbourg, IN2P3, CNRS, IPHC, F-67037 Strasbourg, France Univ Lyon 1, IN2P3, CNRS, IPNL, F-69622 Villeurbanne, France Univ Lyon, F-69361 Lyon 07, France Rhein Westfal TH Aachen, Phys Inst A 3, D-52056 Aachen, Germany Univ Freiburg, Phys Inst, D-79085 Freiburg, Germany Georg August Univ Gottingen, Phys Inst 2, D-37073 Gottingen, Germany Johannes Gutenberg Univ Mainz, Inst Phys, D-55099 Mainz, Germany Ludwig Maximilians Univ Munchen, D-80539 Munich, Germany Panjab Univ, Chandigarh 160014, India Delhi Univ, Delhi 110007, India Tata Inst Fundamental Res, Mumbai 400005, Maharashtra, India Univ Coll Dublin, Dublin 4, Ireland Korea Univ, Korea Detector Lab, Seoul 02841, South Korea CINVESTAV, Mexico City 07360, DF, Mexico Nikhef, Sci Pk, NL-1098 XG Amsterdam, Netherlands Radboud Univ Nijmegen, NL-6525 AJ Nijmegen, Netherlands Joint Inst Nucl Res, Dubna 141980, Russia Inst Theoret & Expt Phys, Moscow 117259, Russia Moscow MV Lomonosov State Univ, Moscow 119991, Russia Inst High Energy Phys, Protvino 142281, Moscow Region, Russia Petersburg Nucl Phys Inst, St Petersburg 188300, Russia Inst Catalana Recerca & Estudis Avancats ICREA, Bellaterra 08193, Barcelona, Spain Inst Fis Altes Energies IFAE, Bellaterra 08193, Barcelona, Spain Uppsala Univ, S-75105 Uppsala, Sweden Taras Shevchenko Natl Univ Kyiv, UA-01601 Kiev, Ukraine Univ Lancaster, Lancaster LA1 4YB, England Imperial Coll London, London SW7 2AZ, England Univ Manchester, Manchester M13 9PL, Lancs, England Univ Arizona, Tucson, AZ 85721 USA Univ Calif Riverside, Riverside, CA 92521 USA Florida State Univ, Tallahassee, FL 32306 USA Fermilab Natl Accelerator Lab, POB 500, Batavia, IL 60510 USA Univ Illinois, Chicago, IL 60607 USA Northern Illinois Univ, De Kalb, IL 60115 USA Northwestern Univ, Evanston, IL 60208 USA Indiana Univ, Bloomington, IN 47405 USA Purdue Univ Calumet, Hammond, IN 46323 USA Univ Notre Dame, Notre Dame, IN 46556 USA Iowa State Univ, Ames, IA 50011 USA Univ Kansas, Lawrence, KS 66045 USA Louisiana Tech Univ, Ruston, LA 71272 USA Northeastern Univ, Boston, MA 02115 USA Univ Michigan, Ann Arbor, MI 48109 USA Michigan State Univ, E Lansing, MI 48824 USA Univ Mississippi, University, MS 38677 USA Univ Nebraska, Lincoln, NE 68588 USA Rutgers State Univ, Piscataway, NJ 08855 USA Princeton Univ, Princeton, NJ 08544 USA SUNY Buffalo, Buffalo, NY 14260 USA Univ Rochester, 601 Elmwood Ave, Rochester, NY 14627 USA SUNY Stony Brook, Stony Brook, NY 11794 USA Brookhaven Natl Lab, Upton, NY 11973 USA Langston Univ, Langston, OK 73050 USA Univ Oklahoma, Norman, OK 73019 USA Oklahoma State Univ, Stillwater, OK 74078 USA Oregon State Univ, Corvallis, OR 97331 USA Brown Univ, Providence, RI 02912 USA Univ Texas Arlington, Arlington, TX 76019 USA Southern Methodist Univ, Dallas, TX 75275 USA Rice Univ, Houston, TX 77005 USA Univ Virginia, Charlottesville, VA 22904 USA Univ Washington, Seattle, WA 98195 USA Augustana Univ, Sioux Falls, SD 57197 USA Kiev Inst Nucl Res KINR, UA-03680 Kiev, Ukraine Univ Liverpool, Liverpool L69 3BX, Merseyside, England US DOE, Off Sci, Washington, DC 20585 USA DESY, Notkestr 85, Hamburg, Germany Russian Acad Sci, PN Lebedev Phys Inst, Moscow 119991, Russia CONACyT, M-03940 Mexico City, DF, Mexico UCL, London WC1E 6BT, England Univ Maryland, College Pk, MD 20742 USA Purdue Univ, W Lafayette, IN 47907 USA Ctr Invest Comp IPN, Mexico City 07738, DF, Mexico Karlsruher Inst Technol KIT, Steinbuch Ctr Comp SCC, D-76128 Karlsruhe, Germany SLAC, Menlo Pk, CA 94025 USA Univ Estadual Paulista, BR-01140 Sao Paulo, SP, Brazil CERN, European Org Nucl Res, CH-1211 Geneva, Switzerland Inst Phys, Belgrade, Serbia Univ Estadual Paulista, BR-01140 Sao Paulo, SP, Brazil Fermi Research Alliance, LLC (FRA): DE-AC02-07CH11359
- Published
- 2020
4. Occupation of Fine-Structure States in Electron Capture and Transport
- Author
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Vernhet, D [Institut des NanoSciences de Paris, Univ. Paris VI]
- Published
- 2008
- Full Text
- View/download PDF
5. Electron Capture and Electron Transport by Fast Ions Penetrating Solids: An Open Quantum System Approach with Sources and Sinks
- Author
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Vernhet, D [Institut des NanoSciences de Paris, Univ. Paris VI]
- Published
- 2007
- Full Text
- View/download PDF
6. Combined Forward-Backward Asymmetry Measurements in Top-Antitop Quark Production at the Tevatron
- Author
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M. Franklin, Gavin Davies, Lorenzo Santi, Y. Scheglov, A. Ruiz, K. Yi, Ping-Kun Teng, Jan Stark, S. Carrillo, Martin Grunewald, Milos Lokajicek, Darien Wood, S. Blessing, P. F. Ding, Scott Snyder, Jonathan Wilson, M. Herndon, Cecilia Elena Gerber, Luigi Marchese, Cecile Deterre, M. Lancaster, Tiehui Ted Liu, Prabhakar Palni, R. St. Denis, A. Fauré, Nikos Varelas, Sally Seidel, C. L. McGivern, Bing Zhou, P. Barria, D. A. Stoyanova, G. Piacentino, L. Brigliadori, Sergey Burdin, Chen Zhou, S. Bhatia, C. Royon, G. Ginther, M. H.L.S. Wang, Taegil Bae, M. C. Cousinou, Pierfrancesco Butti, Y. Seiya, G. Gomez, Christoph Paus, M. Cooke, S. Cihangir, Robert Hirosky, I. Howley, Fumihiko Ukegawa, Kristian Harder, A. Anastassov, Don Lincoln, Erich Varnes, Y. N. Kharzheev, Suyong Choi, P. H. Garbincius, A. Das, P. Svoisky, L. Oakes, S. Fuess, L. Pondrom, Jianming Qian, B. Kilminster, B. Casal, Pietro Marino, Giorgio Bellettini, R. Wallny, Hui Li, M. J. Shochet, Ron Lipton, Y. Sakurai, Virgil E Barnes, John Christian Freeman, K. Devaughan, Andreas Werner Jung, F. Ptohos, A. Elagin, Peter Wagner, Gueorgui Velev, Elliot Lipeles, K. Potamianos, DongHee Kim, S. Rolli, A. Di Canto, Marcelo Vogel, Hugh Williams, M. Iori, Robert Kehoe, Graham Wilson, Massimo Casarsa, W. H. Hopkins, Jongmin Lee, Lidija Zivkovic, Y. D. Oh, A. Kumar, Howard Scott Budd, Christopher Clarke, W. Ketchum, Philip Baringer, Hyun-Chul Kim, T. Kurca, A. Evdokimov, J. Kraus, Matthias Schott, K. Herner, J. Budagov, V. Gavrilov, S. Banerjee, T. Wright, Matthew T Jones, Aliaksandr Pranko, Gordon Watts, Romain Madar, D. Jang, N. Moggi, B. Di Ruzza, Ashutosh Kotwal, N. K. Mondal, Ting Miao, D. Boline, H. T. Diehl, M. Vesterinen, Jieun Kim, Andrew Askew, S. W. Lee, M. M. Deninno, Markus Wobisch, G. Latino, J. Zennamo, A. Dubey, Michael Mulhearn, A. Loginov, L. Feng, G. Golovanov, T. Kamon, Jay Dittmann, S. Amerio, T. Kuhr, A. Simonenko, L. S. Vertogradov, W. Geng, P. Lukens, Boris Tuchming, V. Glagolev, D. Stentz, A. S. Ito, T. Aaltonen, B. Hoeneisen, D. J. Cox, Q. Liu, D. Cruz, C. Bromberg, J. Clutter, Maxim Perfilov, R. McNulty, M. Hare, A. Drutskoy, J. K. Lim, A. Lucà, K. Pitts, Y. T. Tsai, C. Pagliarone, A. Boehnlein, Mark Raymond Adams, D. Karmanov, H. Hegab, V. Parihar, E. De La Cruz-Burelo, Stefano Giagu, John Hobbs, M. Hohlfeld, Antonio Boveia, Gregorio Bernardi, B. Carls, V. Sorin, A. Mazzacane, A. V. Popov, R. D. Schamberger, J. T. Linnemann, U. K. Yang, J. Nachtman, A. S. Santos, E. Brucken, Phillip Gutierrez, Frederic Deliot, G. P. Yeh, Douglas Benjamin, C. S. Moon, D. Menezes, Stanislav Tokár, Kohei Yorita, D. Glenzinski, Hal Evans, T. Head, D.P. Brown, Seo-Young Noh, P. Mazzanti, J. R. Smith, G. B. Yu, J. Ellison, Emanuela Barberis, Yuji Enari, K. Soustruznik, Elemer Nagy, S. Y. Jun, G. Savage, T. G. Zhao, W. Ye, V. Aushev, J. Conway, Thomas Ferbel, M. Prewitt, Nazar Stefaniuk, Yuji Takeuchi, J. Weichert, Song-Ming Wang, Y. Aushev, G. Grenier, F. Miconi, E. Kajfasz, A. P. Heinson, J. Boudreau, Jose Andres Garcia-Gonzalez, Kazuhiro Yamamoto, M. Savitskyi, Andrew Brandt, L. Bellantoni, A. Ivanov, S. Dutt, S. Caughron, C. Galloni, J. Nett, J. Warchol, J. Konigsberg, A. Kasmi, Pavol Bartos, L. Bagby, Oleg Brandt, Bjoern Penning, Franco Rimondi, Maria Rescigno, H. E. Fisk, D. Lucchesi, W. Ashmanskas, Sudhir Malik, L. Ristori, Ia Iashvili, Adrian Buzatu, J. Keung, G. C. Blazey, D. Torretta, L. Nodulman, A. Sukhanov, Andrew Beretvas, Brajesh C Choudhary, V. V. Lipaev, J. Lellouch, M. A. Pleier, A. Alton, T. Nigmanov, A. Mukherjee, R. Forrest, Giovanni Busetto, Y. Sudo, I. Suslov, Maxim Goncharov, Kunitaka Kondo, Richard D Field, V. E. Bazterra, N. Khalatyan, R. Ruchti, Thibault Guillemin, P. D. Grannis, P. Jiang, R. Yamada, P. Mehtala, Sandra Leone, P. Totaro, I. Ripp-Baudot, Hao Song, L. Scodellaro, J. Orduna, T. Yoshida, Manfredi Ronzani, Sinead Farrington, Andrea Bocci, D. Li, V. L. Malyshev, A. Y. Verkheev, Jeffrey A. Appel, S. Lammel, Giovanni Punzi, O. Norniella, Manfred Paulini, Manuela Campanelli, V. A. Kuzmin, H. Wolfmeister, Fabrice Couderc, F. Badaud, F. Happacher, B. Baldin, N. d’Ascenzo, M. Borysova, Sung Keun Park, Guillelmo Gomez-Ceballos, M. Titov, Christopher George Tully, Aran Garcia-Bellido, K. Hatakeyama, Young-Jin Kim, R. Illingworth, D. Mietlicki, Mitchell Wayne, H. Schellman, S. Torre, J. M. Kohli, L. Ortolan, D. Cauz, W. E. Cooper, A. Jayasinghe, P. Slattery, V. Giakoumopoulou, A. Sánchez-Hernández, S. Poprocki, E. Gramellini, William Wester, Adam Aurisano, S. J. De Jong, C. Hensel, P. Skubic, Joey Huston, P. Wittich, Ziqing Hong, Katsufumi Sato, O. Gogota, B. Jayatilaka, Daniel R Claes, R. Vilar, B. Auerbach, Liang Li, M. Corbo, Jean-Arcady Meyer, Davit Chokheli, J. Y. Han, F. Margaroli, O. Gonzalez Lopez, A. Bhatti, D. Hedin, F. Devoto, S. Leo, M. Mussini, V. Rusu, L. Welty-Rieger, Marc Besancon, Stefan Grünendahl, Elizaveta Shabalina, M. J. Morello, S. R. Hou, P. E. Karchin, A. Chapelain, S. Errede, Eugene E. Schmidt, Emily Johnson, D. Yamato, A. Golossanov, Vaia Papadimitriou, Alessandro Cerri, A. Mitra, Marco Verzocchi, G. Flanagan, J. P. Agnew, Dmitri Tsybychev, P. Lebrun, Yongsun Kim, Lev Dudko, Nikos Giokaris, A. Grohsjean, Y. C. Chen, V. Saveliev, Dmitri Denisov, J. Russ, Stephen R. Hahn, M. Kurata, R. Madrak, M. Buehler, J. Naganoma, L. Sonnenschein, L. Demortier, Chris Hays, Seog Oh, J. Sekaric, Michael A. Strauss, Maxwell Chertok, A. Patwa, H. Gerberich, J. Joshi, J. Martínez-Ortega, Yang Yang, Zdenek Hubacek, E. Palencia, Giorgio Chiarelli, R. E. Hughes, J. Antos, B. A. Barnett, Giorgio Apollinari, Pedro G Mercadante, S. Atkins, G. Pauletta, Adam L. Lyon, J. P. Negret, Victor Daniel Elvira, K. R. Bland, K. Takemasa, V. M. Podstavkov, P. F. Shepard, Arnaud Duperrin, Carlos Avila, K. Lannon, Eric B James, E. J. Jeon, F. Vázquez, D. Waters, Kazuhiko Hara, M. Fortner, A. Chandra, Satoru Uozumi, U. Bassler, S. Kim, Mark Edward Mattson, Alberto Annovi, S. Zucchelli, Ulrich Heintz, S. Söldner-Rembold, M. Eads, Kenneth Johns, J. Vizán, Marcia Begalli, M. Jaffré, C. A. Cox, Joseph Haley, H. Miyake, J. L. Holzbauer, Kihyeon Cho, Yoshikazu Nagai, P. N. Ratoff, Y. Peters, J. Franc, R. Luna-Garcia, Mousumi Datta, J. Lueck, Lucio Cerrito, R. Roser, Frank Filthaut, Regina Demina, Meenakshi Narain, J. Yoh, F. Bedeschi, T. Harrington-Taber, Y. Zeng, N. Prokopenko, M. Kambeitz, Mark Richard James Williams, Michael Hildreth, W. M. Lee, H. Greenlee, Claus P. Buszello, Ph Gris, T. Hoang, Yujiro Funakoshi, M. Diesburg, Darren Price, Hang Yin, A. Bross, R. Magaña-Villalba, G. Chen, J. Snow, A. A. Shchukin, E. Gerchtein, Fedor Prokoshin, H. T. Nguyen, M. Hussein, S. Z. Shalhout, R. Nayyar, S. Uzunyan, V. Bhatnagar, Alexander Kupco, Emilien Chapon, V. Simak, P. de Barbaro, T. Okusawa, T. Scanlon, T. Yang, Guennadi Borissov, J. Strologas, Y. A. Yatsunenko, Arnd Meyer, T. Rodriguez, James Nugent Bellinger, M. Cordelli, S. Kermiche, Anthony Ross, Shabnam Jabeen, Savanna Marie Shaw, Suman Bala Beri, Barry Blumenfeld, B. L. Winer, T. Tomura, Frank Fiedler, J. Asaadi, M. Merkin, Pierluigi Catastini, S. Chakrabarti, I. Katsanos, M. Dorigo, I. Heredia-De La Cruz, E. E. Boos, N. Parua, M. Tecchio, D. Toback, Arnulf Quadt, Alexander Khanov, R. Carosi, Alfred Goshaw, V. Hynek, A. Hocker, R. Bernhard, Amnon Harel, C. Schwanenberger, U. Husemann, Heriberto Castilla-Valdez, W. C. Fisher, W. Parker, M. Kaur, V. V. Tokmenin, G. Alkhazov, Charles Plager, Roman Lysak, S. Donati, K. Matera, D. Amidei, J. M. Yu, Karen Ruth Gibson, Antonio Limosani, P. Rubinov, M. Vidal, D. Vilanova, M. Cremonesi, Q. Z. Li, Lev Uvarov, V. M. Abazov, P. Wilson, Naoki Kimura, Mark Kruse, Alison Lister, I. Kiselevich, Bobby Samir Acharya, H. A. Neal, V. Shary, Daniela Bortoletto, S. Wilbur, C.M. Ginsburg, Pushpalatha C Bhat, Raymond Brock, K. Yip, S. H. Kim, D. V. Bandurin, Raymond Lloyd Culbertson, Jeremy Lys, R. Van Kooten, Neeti Parashar, J. Hogan, A. Juste, K. Petridis, T. Nunnemann, R. Beuselinck, W-M. Yao, Todd Adams, Javier Cuevas, V. Thukral, Jason Dhia Mansour, S. Greder, Iain Alexander Bertram, G. Chlachidze, Yanwen Liu, H. Frisch, A. K.A. Maciel, Lee Sawyer, C. Vellidis, S. Moed, K. Goulianos, Y. Xie, Fabrizio Scuri, J. P. Fernández Ramos, P. Giromini, Michal Kreps, A. Artikov, I. Razumov, M. Zielinski, A. Barbaro-Galtieri, M. D. Corcoran, Gianluca Introzzi, W. Badgett, M. Stancari, Arie Bodek, J. Hays, G. Gutierrez, P. Renton, Evelyn Thomson, V. N. Evdokimov, Th. Müller, M. Rominsky, M. Shimojima, K. Sliwa, P. Neustroev, Sabine Lammers, N. Osman, Liyuan Han, Jakub Cúth, A. Driutti, G. Lungu, R. Jesik, Kyung Kwang Joo, D. Edmunds, R. Lopes De Sá, M. J. Kim, Duncan Carlsmith, Thomas J. Phillips, Andrew Mehta, Zhenyu Ye, Yuri Gershtein, S. Lockwitz, Andrea Castro, A. T. Laasanen, G. D. Alexeev, Flera Rizatdinova, E. Camacho-Pérez, I. Yu, Reinhard Schwienhorst, A. M. Zanetti, Stefano Camarda, Jean-Francois Grivaz, G. Manca, J. Pilot, Arthur Barry Wicklund, Michael S. Gold, Kwok Ming Chan, Yuriy Ilchenko, X. Lei, Daniel Whiteson, Paolo Maestro, Michael H Kirby, A. Jonckheere, A. Semenov, F. Ruffini, A. Lobodenko, M. P. Sanders, B. Esham, M. Brochmann, Aidan Robson, A. Melnitchouk, S. Behari, Daria Zieminska, M. D'Errico, Y. Kato, J. Guimaraes Da Costa, D. Tonelli, A. Napier, T. R. Wyatt, I. V. Gorelov, Zhenbin Wu, R. Erbacher, P. Jonsson, Kamil Augsten, A. Pal, S. W. Youn, Thomas Hebbeker, J. M. Hauptman, A. Kharchilava, Siqi Yang, Elisabetta Pianori, I. Shreyber-Tecker, O. Shkola, Federico Sforza, Brad Abbott, Pierre Petroff, Gregory R Snow, Sergey Denisov, Viviana Cavaliere, G. Sajot, Horst Severini, Hakjae Lee, W. M. Van Leeuwen, Junjie Zhu, Joe Kroll, B. C.K. Casey, S. Wolbers, P. Lujan, Monica D'Onofrio, T. R. Junk, G. Petrillo, J. Tang, Jonathan Lewis, S. Uvarov, Marvin Johnson, Philip Schlabach, M. Trovato, A. V. Kozelov, Jonathan L. Rosner, B. Quinn, C. Mesropian, X. B. Bu, K. Ebina, Alice Bean, Willis Kazuo Sakumoto, Ryan Christopher Edgar, Xin Wu, T. A. Schwarz, C. Grosso-Pilcher, Viacheslav Bunichev, Volker Buescher, Peter Bussey, H. D. Wahl, Florencia Canelli, Matteo Bauce, Tara Shears, D. J. Kong, S. Desai, D. Goldin, Petr Vokac, Kirsten Tollefson, J. Thom, Risto Orava, M. M. Meijer, Kevin Burkett, T. Yasuda, P. Garosi, Aaron Dominguez, Jochen Jens Heinrich, I. Redondo Fernández, H. Liu, F. D. Snider, C. Vernieri, Guido Volpi, Itsuo Nakano, Harald Fox, Aurore Savoy-Navarro, S. W. Cho, A. Manousakis-Katsikakis, Allan G Clark, Roger Moore, F. Azfar, David Cutts, M. E. Convery, T. Arisawa, Alan Garfinkel, James G. Bartlett, L. Suter, S. Jindariani, P. Murat, I. A. Vasilyev, A. Calamba, R. Partridge, Kenneth Bloom, R. McCarthy, M. S. Jeong, Gavin Grant Hesketh, R. F. Harr, Aaltonen, T., Abazov, V. M., Abbott, B., Acharya, B. S., Adams, M., Adams, T., Agnew, J. P., Alexeev, G. 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E., Flanagan, G., Forrest, R., Fortner, M., Fox, H., Franc, J., Franklin, M., Freeman, J. C., Frisch, H., Fuess, S., Funakoshi, Y., Galloni, C., Garbincius, P. H., Garcia-Bellido, A., Garcia-Gonzalez, J. A., Garfinkel, A. F., Garosi, P., Gavrilov, V., Geng, W., Gerber, C. E., Gerberich, H., Gerchtein, E., Gershtein, Y., Giagu, S., Giakoumopoulou, V., Gibson, K., Ginsburg, C. M., Ginther, G., Giokaris, N., Giromini, P., Glagolev, V., Glenzinski, D., Gogota, O., Gold, M., Goldin, D., Golossanov, A., Golovanov, G., Gomez, G., Gomez-Ceballos, G., Goncharov, M., Gonzalez Lopez, O., Gorelov, I., Goshaw, A. T., Goulianos, K., Gramellini, E., Grannis, P. D., Greder, S., Greenlee, H., Grenier, G., Gris, Ph., Grivaz, J. -F., Grohsjean, A., Grosso-Pilcher, C., Grunendahl, S., Grunewald, M. W., Guillemin, T., da Costa, J. Guimarae, Gutierrez, G., Gutierrez, P., Hahn, S. R., Haley, J., Han, J. Y., Han, L., Happacher, F., Hara, K., Harder, K., Hare, M., Harel, A., Harr, R. 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E., Karmanov, D., Kasmi, A., Kato, Y., Katsanos, I., Kaur, M., Kehoe, R., Kermiche, S., Ketchum, W., Keung, J., Khalatyan, N., Khanov, A., Kharchilava, A., Kharzheev, Y. N., Kilminster, B., Kim, D. H., Kim, H. S., Kim, J. E., Kim, M. J., Kim, S. H., Kim, S. B., Kim, Y. J., Kim, Y. K., Kimura, N., Kirby, M., Kiselevich, I., Kohli, J. M., Kondo, K., Kong, D. J., Konigsberg, J., Kotwal, A. V., Kozelov, A. V., Kraus, J., Kreps, M., Kroll, J., Kruse, M., Kuhr, T., Kumar, A., Kupco, A., Kurata, M., Kurca, T., Kuzmin, V. A., Laasanen, A. T., Lammel, S., Lammers, S., Lancaster, M., Lannon, K., Latino, G., Lebrun, P., Lee, H. S., Lee, J. S., Lee, S. W., Lee, W. M., Lei, X., Lellouch, J., Leo, S., Leone, S., Lewis, J. D., Li, D., Li, H., Li, L., Li, Q. Z., Lim, J. K., Limosani, A., Lincoln, D., Linnemann, J., Lipaev, V. V., Lipeles, E., Lipton, R., Lister, A., Liu, H., Liu, Q., Liu, T., Liu, Y., Lobodenko, A., Lockwitz, S., Loginov, A., Lokajicek, M., de Sa, R. 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Y., Norniella, O., Nunnemann, T., Oakes, L., Oh, S. H., Oh, Y. D., Okusawa, T., Orava, R., Orduna, J., Ortolan, L., Osman, N., Pagliarone, C., Pal, A., Palencia, E., Palni, P., Papadimitriou, V., Parashar, N., Parihar, V., Park, S. K., Parker, W., Partridge, R., Parua, N., Patwa, A., Pauletta, G., Paulini, M., Paus, C., Penning, B., Perfilov, M., Peters, Y., Petridis, K., Petrillo, G., Petroff, P., Phillips, T. J., Piacentino, G., Pianori, E., Pilot, J., Pitts, K., Plager, C., Pleier, M. -A., Podstavkov, V. M., Pondrom, L., Popov, A. V., Poprocki, S., Potamianos, K., Pranko, A., Prewitt, M., Price, D., Prokopenko, N., Prokoshin, F., Ptohos, F., Punzi, G., Qian, J., Quadt, A., Quinn, B., Ratoff, P. N., Razumov, I., Redondo Fernandez, I., Renton, P., Rescigno, M., Rimondi, F., Ripp-Baudot, I., Ristori, L., Rizatdinova, F., Robson, A., Rodriguez, T., Rolli, S., Rominsky, M., Ronzani, M., Roser, R., Rosner, J. 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Department of Physics, Massachusetts Institute of Technology. Laboratory for Nuclear Science, Gomez-Ceballos, Guillelmo, Goncharov, Maxim, Paus, Christoph M. E., Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Laboratoire de Physique de Clermont ( LPC ), Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Université Clermont Auvergne ( UCA ) -Centre National de la Recherche Scientifique ( CNRS ), Institut de Recherches sur les lois Fondamentales de l'Univers ( IRFU ), Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay, Laboratoire de Physique Nucléaire et de Hautes Énergies ( LPNHE ), Université Pierre et Marie Curie - Paris 6 ( UPMC ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Université Paris Diderot - Paris 7 ( UPD7 ) -Centre National de la Recherche Scientifique ( CNRS ), Centre de Physique des Particules de Marseille ( CPPM ), Centre National de la Recherche Scientifique ( CNRS ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Aix Marseille Université ( AMU ), Institut Pluridisciplinaire Hubert Curien ( IPHC ), Centre National de la Recherche Scientifique ( CNRS ) -Université de Strasbourg ( UNISTRA ), Institut de Physique Nucléaire de Lyon ( IPNL ), Université Claude Bernard Lyon 1 ( UCBL ), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Centre National de la Recherche Scientifique ( CNRS ), Laboratoire de l'Accélérateur Linéaire ( LAL ), Université Paris-Sud - Paris 11 ( UP11 ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Centre National de la Recherche Scientifique ( CNRS ), Laboratoire de Physique Subatomique et de Cosmologie ( LPSC ), Université Joseph Fourier - Grenoble 1 ( UJF ) -Institut polytechnique de Grenoble - Grenoble Institute of Technology ( Grenoble INP ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique ( CNRS ) -Université Grenoble Alpes ( UGA ), Abazov, V.M., Acharya, B.S., Agnew, J.P., Alexeev, G.D., Appel, J.A., Bandurin, D.V., Barnes, V.E., Barnett, B.A., Bartlett, J.F., Beri, S.B., Besançon, M., Bhat, P.C., Bland, K.R., Boos, E.E., Bu, X.B., Budd, H.S., Buszello, C.P., Camacho-Pérez, E., Casey, B.C.K., Chan, K.M., Chen, Y.C., Cho, S.W., Convery, M.E., Cooper, W.E., Cousinou, M.-C., Cox, C.A., Cox, D.J., De Barbaro, P., De Jong, S.J., Déliot, F., Denisov, S.P., Diehl, H.T., Ding, P.F., Dittmann, J.R., Dudko, L.V., Elvira, V.D., Evdokimov, V.N., Fauré, A., Fernández Ramos, J.P., Fisk, H.E., Freeman, J.C., Garbincius, P.H., García-González, J.A., Garfinkel, A.F., Gerber, C.E., Ginsburg, C.M., González López, O., Goshaw, A.T., Grannis, P.D., Grivaz, J.-F., Grünendahl, S., Grünewald, M.W., Guimaraes Da Costa, J., Hahn, S.R., Han, J.Y., Harr, R.F., Hauptman, J.M., Heinson, A.P., Hildreth, M.D., Hobbs, J.D., Holzbauer, J.L., Hughes, R.E., Ito, A.S., Jaffré, M., Jeon, E.J., Jeong, M.S., Joo, K.K., Jun, S.Y., Jung, A.W., Junk, T.R., Karchin, P.E., Kharzheev, Y.N., Kim, D.H., Kim, H.S., Kim, J.E., Kim, M.J., Kim, S.H., Kim, S.B., Kim, Y.J., Kim, Y.K., Kohli, J.M., Kong, D.J., Kotwal, A.V., Kozelov, A.V., Kurča, T., Kuzmin, V.A., Laasanen, A.T., Lee, H.S., Lee, J.S., Lee, S.W., Lee, W.M., Lewis, J.D., Li, Q.Z., Lim, J.K., Lipaev, V.V., Lopes De Sa, R., Lucà, A., Lyon, A.L., Maciel, A.K.A., Magaña-Villalba, R., Malyshev, V.L., Martínez-Ortega, J., Mattson, M.E., McCarthy, R., McGivern, C.L., McNulty, R., Meijer, M.M., Mercadante, P.G., Mondal, N.K., Moon, C.S., Morello, M.J., Neal, H.A., Negret, J.P., Nguyen, H.T., Noh, S.Y., Oh, S.H., Oh, Y.D., Park, S.K., Pétroff, P., Phillips, T.J., Pleier, M.-A., Podstavkov, V.M., Popov, A.V., Ratoff, P.N., Redondo Fernández, I., Rosner, J.L., Sakumoto, W.K., Sánchez-Hernández, A., Sanders, M.P., Santos, A.S., Schamberger, R.D., Schmidt, E.E., Shalhout, S.Z., Shchukin, A.A., Shepard, P.F., Smith, J.R., Snider, F.D., Snow, G.R., Söldner-Rembold, S., St Denis, R., Stoyanova, D.A., Teng, P.K., Tokmenin, V.V., Tsai, Y.-T., Van Leeuwen, W.M., Varnes, E.W., Vasilyev, I.A., Vázquez, F., Verkheev, A.Y., Vertogradov, L.S., Vizán, J., Wahl, H.D., Wang, M.H.L.S., Wang, S.M., Wester, W.C., Wicklund, A.B., Williams, H.H., Williams, M.R.J., Wilson, G.W., Wilson, J.S., Winer, B.L., Wood, D.R., Wyatt, T.R., Yang, U.K., Yang, Y.C., Yao, W.-M., Yatsunenko, Y.A., Yeh, G.P., Youn, S.W., Yu, G.B., Yu, J.M., Zanetti, A.M., Zhao, T.G., Clark, Allan Geoffrey, Lister, Alison, Wu, Xin, and Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)
- Subjects
Top quark ,Tevatron ,General Physics and Astronomy ,pair production [top] ,01 natural sciences ,7. Clean energy ,High Energy Physics - Experiment ,Subatomär fysik ,High Energy Physics - Experiment (hep-ex) ,DZERO ,Subatomic Physics ,ddc:550 ,[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex] ,Quantum Chromodynamics ,Batavia TEVATRON Coll ,GeneralLiterature_REFERENCE(e.g.,dictionaries,encyclopedias,glossaries) ,media_common ,Physics ,scattering [anti-p p] ,Particle properties ,02 Physical Sciences ,rapidity: difference ,CDF ,top-quark ,difference [rapidity] ,asymmetry [angular distribution] ,kinematics ,Physical Sciences ,top: pair production ,Quark ,Particle physics ,General Physics ,angular distribution: asymmetry ,Tevatron Collider ,media_common.quotation_subject ,Physics, Multidisciplinary ,FOS: Physical sciences ,Forward backward ,ddc:500.2 ,Hadron-hadron interactions ,Asymmetry ,Computer Science::Digital Libraries ,114 Physical sciences ,Marie curie ,CDF Collaboration ,anti-p p: colliding beams ,Physics and Astronomy (all) ,[ PHYS.HEXP ] Physics [physics]/High Energy Physics - Experiment [hep-ex] ,0103 physical sciences ,anti-p p: scattering ,media_common.cataloged_instance ,ddc:530 ,High Energy Physics ,European union ,010306 general physics ,Science & Technology ,1960 GeV-cms ,010308 nuclear & particles physics ,hep-ex ,High Energy Physics::Phenomenology ,Q007TFB ,Research council ,Experimental High Energy Physics ,High Energy Physics::Experiment ,colliding beams [anti-p p] ,High Energy Physics, Top quark, Hadron-hadron interactions, Quantum Chromodynamics, Particle properties, Tevatron Collider ,D0 Collaboration ,experimental results - Abstract
The CDF and D0 experiments at the Fermilab Tevatron have measured the asymmetry between yields of forward- and backward-produced top and antitop quarks based on their rapidity difference and the asymmetry between their decay leptons. These measurements use the full data sets collected in proton-antiproton collisions at a center-of-mass energy of √s=1.96 TeV. We report the results of combinations of the inclusive asymmetries and their differential dependencies on relevant kinematic quantities. The combined inclusive asymmetry is At¯tFB=0.128±0.025. The combined inclusive and differential asymmetries are consistent with recent standard model predictions., Physical Review Letters, 120 (4), ISSN:0031-9007, ISSN:1079-7114
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- 2018
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7. On the symmetries of integrability
- Author
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Viallet, C [Lab. de Physique Theorique et de Hautes Energies, Univ. Paris VI, Tour 16, 1 etage, boite 126, 4 Place Jussieu, F-75252 Paris Cedex 05 (FR)]
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- 1992
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8. A model for coupled magnetic-electric circuits in electric machines with skewed slots
- Author
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Razek, a [Laboratoire de Genie Electrique de Paris, L.A. 127 C.N.R.S., Ecole Superieure d'Electricite, Univ. Paris VI et XI, Plateau du Moulon, 91190 Gig/Yvette (FR)]
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- 1990
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9. Combination of D0 measurements of the top quark mass
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Sung Keun Park, Ulrich Heintz, Frank Filthaut, M. Diesburg, W. M. Lee, M. C. Cousinou, J. P. Negret, Pushpalatha C Bhat, Guennadi Borissov, R. Luna-Garcia, Michael Hildreth, I. Heredia-De La Cruz, W. M. Van Leeuwen, Vipin Bhatnagar, B. S. Acharya, W. C. Fisher, J. F. Bartlett, P. N. Ratoff, Graham Wilson, Robert Kehoe, Y. Peters, S. W. Youn, Ruchika Nayyar, Maksym Titov, J. Kraus, Brad Abbott, Pierre Petroff, Neeti Parashar, Xiaowen Lei, J. Hogan, V. V. Tokmenin, V. Aushev, Robert Hirosky, Lidija Zivkovic, H. Hegab, V. Parihar, A. S. Ito, Christopher George Tully, Darren Price, Don Lincoln, Erich Varnes, G. Alkhazov, Y. W. Liu, V. E. Bazterra, I. Razumov, B. Hoeneisen, Lee Sawyer, Marco Verzocchi, J. P. Agnew, R. Lopes De Sá, V. V. Shary, Avto Kharchilava, T. Hoang, Alexander Khanov, R. Partridge, M. Zielinski, G. Gutierrez, Hongfang Liu, Marc Besancon, J. Hays, Emanuela Barberis, S. Cihangir, Fabrice Couderc, Patrick Slattery, H. D. Wahl, G. Bernardi, M. Vesterinen, A. Patwa, D. R. Claes, Gavin Davies, R. Van Kooten, M. D. Corcoran, L. Han, R. Madar, V. V. Lipaev, J. Lellouch, Emily Johnson, H. T. Nguyen, S. Uzunyan, O. Shkola, H. A. Neal, Ashok Kumar, Kenneth Bloom, C. Royon, Thibault Guillemin, M. Borysova, J. K. Lim, D. Edmunds, Y. Scheglov, K. Yip, D. A. Stoyanova, Liang Li, M. M. Meijer, Edouard Boos, A. V. Popov, T. Nunnemann, Angelo De Souza Santos, B. Baldin, V. L. Malyshev, Marcia Begalli, Shangfeng Yang, J. Snow, Amnon Harel, Jason Dhia Mansour, John Hobbs, L. S. Vertogradov, Zhenyu Ye, G. J. Grenier, R. Jesik, Yuri Gershtein, A. Jayasinghe, T. Yasuda, A. P. Heinson, Markus Wobisch, I. Ripp-Baudot, Lev Dudko, O. Gogota, Meenakshi Narain, Y. A. Yatsunenko, M. R. Adams, Cecile Deterre, M. A. Pleier, Aaron Dominguez, A. Meyer, E. Camacho-Pérez, Emilien Chapon, M. S. Jeong, V. M. Abazov, A. Melnitchouk, A. Jonckheere, V. A. Kuzmin, S. J. De Jong, J. Haley, F. Miconi, I. Howley, Sergey Burdin, J. Zennamo, A. Dubey, Reinhard Schwienhorst, Zdenek Hubacek, A. 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Cho, W. Geng, E. De La Cruz-Burelo, Volker Buescher, Nazar Stefaniuk, Jan Stark, D. Vilanova, Randy Ruchti, K. A. Johns, Gianluca Petrillo, P. Skubic, A. Fauré, Nikos Varelas, C. L. McGivern, Bing Zhou, Shabnam Jabeen, G. D. Alexeev, Flera Rizatdinova, S. Atkins, Frederic Deliot, M. Merkin, N. Khalatyan, Hang Yin, D. Denisov, P. H. Garbincius, R. D. Schamberger, Andrew Brandt, K. Devaughan, Martin Grunewald, Andreas Werner Jung, Raymond Brock, L. Feng, M. P. Sanders, D. Hedin, Ji Zhu, Milos Lokajicek, A. Sanchez-Hernandez, Vladimir Gavrilov, Gordon Watts, R. Beuselinck, G. Savage, N. K. Mondal, D. Boline, H. T. Diehl, Savanna Marie Shaw, Heriberto Castilla-Valdez, Hal Evans, Thomas Ferbel, M. Prewitt, Darien Wood, J. Clutter, A. Boehnlein, Y. Xie, Lars Sonnenschein, S. Caughron, Arnulf Quadt, Carsten Hensel, Andrew Askew, Phillip Gutierrez, S. Blessing, J. Weichert, P. Neustroev, Harald Fox, D. Karmanov, J. Ellison, V. Simak, Sabine Lammers, Y. Aushev, S. Fuess, P. F. Ding, Scott Snyder, Maxim Perfilov, T. Kurca, Elemer Nagy, T. G. Zhao, W. Ye, L. Suter, I. A. Vasilyev, Sudhir Malik, Ia Iashvili, M. H.L.S. Wang, Shih-Chang Lee, L. Bellantoni, M. Savitskyi, J. Warchol, N. Osman, Jakub Cúth, Brajesh C Choudhary, P. D. Grannis, S. Greder, Mitchell Wayne, D. Li, H. Schellman, J. M. Kohli, Anthony Ross, Alexander Grohsjean, Stefan Grünendahl, Lev Uvarov, M. Buehler, Q. Z. Li, I. Kiselevich, A. Juste, K. Petridis, J. L. Holzbauer, Mark Richard James Williams, A. K.A. Maciel, D. Menezes, Suneel Dutt, A. Alton, Y. N. Kharzheev, Jean-Arcady Meyer, L. Bagby, J. M. Hauptman, Cecilia Elena Gerber, K. M. Chan, G. Ginther, Jianming Qian, Ph. Lebrun, Elizaveta Shabalina, Y. T. Tsai, U. Bassler, X. B. Bu, Y. Ilchenko, S. Desai, Petr Vokac, Regina Demina, Jose Andres Garcia-Gonzalez, Claus P. Buszello, P. G. Mercadante, B. C.K. Casey, R. Illingworth, G. C. Blazey, P. Jiang, R. Yamada, S. Bhatia, Marvin Johnson, A. L. Lyon, A. V. Kozelov, Jean-Francois Grivaz, S. Chakrabarti, P. Jonsson, A. Pal, Thomas Hebbeker, P. Rubinov, Philip Baringer, Matthias Schott, K. Herner, H. E. Fisk, S. Banerjee, A. Y. Verkheev, Aran Garcia-Bellido, Gavin Grant Hesketh, G. Sajot, Horst Severini, Hakjae Lee, Richard B. Lipton, Kristian Harder, D. Cutts, Manjit Kaur, K. Soustruznik, V. Bunichev, Ctr Brasileiro Pesquisas Fis, Universidade do Estado do Rio de Janeiro (UERJ), Universidade Federal do ABC (UFABC), Univ Sci & Technol China, Univ Los Andes, Charles Univ Prague, Czech Tech Univ, Acad Sci Czech Republ, Univ San Francisco Quito, Univ Blaise Pascal, Univ Joseph Fourier Grenoble 1, Inst Natl Polytech Grenoble, Aix Marseille Univ, Univ Paris Saclay, Univ Paris VI, Universidade de São Paulo (USP), CEA Saclay, Univ Strasbourg, Univ Lyon 1, Univ Lyon, Rhein Westfal TH Aachen, Univ Freiburg, Georg August Univ Gottingen, Johannes Gutenberg Univ Mainz, Ludwig Maximilians Univ Munchen, Panjab Univ, Delhi Univ, Inst Fundamental Res, Univ Coll Dublin, Korea Univ, CINVESTAV, Nikhef, Radboud Univ Nijmegen, Joint Inst Nucl Res, Inst Theoret & Expt Phys, Moscow MV Lomonosov State Univ, Inst High Energy Phys, Petersburg Nucl Phys Inst, ICREA, IFAE, Uppsala Univ, Taras Shevchenko Natl Univ Kyiv, Univ Lancaster, Imperial Coll London, Univ Manchester, Univ Arizona, Univ Calif Riverside, Florida State Univ, Fermilab Natl Accelerator Lab, Univ Illinois, Northern Illinois Univ, Northwestern Univ, Indiana Univ, Purdue Univ Calumet, Univ Notre Dame, Iowa State Univ, Univ Kansas, Louisiana Tech Univ, Northeastern Univ, Univ Michigan, Michigan State Univ, Univ Mississippi, Univ Nebraska, Rutgers State Univ, Princeton Univ, SUNY Buffalo, Univ Rochester, SUNY Stony Brook, Brookhaven Natl Lab, Langston Univ, Univ Oklahoma, Oklahoma State Univ, Oregon State Univ, Brown Univ, Univ Texas Arlington, Southern Methodist Univ, Rice Univ, Univ Virginia, Univ Washington, Augustana Coll, Univ Liverpool, Deutshes Elektronen Synchrotron DESY, CONACyT, SLAC, UCL, IPN, Universidade Estadual Paulista (Unesp), Karlsruher Inst Technol, US DOE, Amer Assoc Advancement Sci, Kiev Inst Nucl Res, Univ Maryland, CERN, Purdue Univ, Inst Phys, Laboratoire de Physique de Clermont (LPC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Clermont Auvergne (UCA)-Centre National de la Recherche Scientifique (CNRS), Département de Physique des Particules (ex SPP) (DPP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Centre de Physique des Particules de Marseille (CPPM), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Aix Marseille Université (AMU), Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Institut de Physique Nucléaire de Lyon (IPNL), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de l'Accélérateur Linéaire (LAL), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), D0, Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre National de la Recherche Scientifique (CNRS), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Rio de Janeiro, University of Science and Technology of China, Universidad de Los Andes, Center for Particle Physics, Czech Technical University in Prague, Academy of Sciences of the Czech Republic, Universidad San Francisco de Quito, Clermont, Institut National Polytechnique de Grenoble, CNRS/IN2P3, Université Paris-Saclay, SPPC, RWTH Aachen University, Universität Freiburg, Georg-August-Universität Göttingen, Universität Mainz, Ludwig-Maximilians-Universität München, Panjab University, Delhi University, Tata Institute of Fundamental Research, University College Dublin, Korea University, Radboud University Nijmegen, Joint Institute for Nuclear Research, Institute for Theoretical and Experimental Physics, Moscow State University, Institute for High Energy Physics, Petersburg Nuclear Physics Institute, Institut de Física d'Altes Energies (IFAE), Uppsala University, Taras Shevchenko National University of Kyiv, Lancaster University, Imperial College London, University of Manchester, University of Arizona, University of California Riverside, Florida State University, Fermi National Accelerator Laboratory, University of Illinois at Chicago, Northern Illinois University, Northwestern University, Indiana University, Purdue University Calumet, University of Notre Dame, Iowa State University, University of Kansas, Louisiana Tech University, Northeastern University, University of Michigan, Michigan State University, University of Mississippi, University of Nebraska, Rutgers University, Princeton University, State University of New York, University of Rochester, Brookhaven National Laboratory, Langston University, University of Oklahoma, Oklahoma State University, Oregon State University, Brown University, University of Texas, Southern Methodist University, Rice University, University of Virginia, University of Washington, Belgrade, Augustana College, University of Liverpool, Deutshes Elektronen-Synchrotron (DESY), University College London, Centro de Investigacion en Computacion IPN, Universidade Estadual Paulista (UNESP), Steinbuch Centre for Computing (SCC), U.S. Department of Energy, American Association for the Advancement of Science, Kiev Institute for Nuclear Research (KINR), University of Maryland, European Organization for Nuclear Research (CERN), Purdue University, Université de Lyon, Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Département de Physique des Particules (ex SPP) (DPhP), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique de Clermont ( LPC ), Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Université Clermont Auvergne ( UCA ) -Centre National de la Recherche Scientifique ( CNRS ), Département de Physique des Particules (ex SPP) ( DPP ), Institut de Recherches sur les lois Fondamentales de l'Univers ( IRFU ), Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay, Laboratoire de Physique Nucléaire et de Hautes Énergies ( LPNHE ), Université Pierre et Marie Curie - Paris 6 ( UPMC ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Université Paris Diderot - Paris 7 ( UPD7 ) -Centre National de la Recherche Scientifique ( CNRS ), Centre de Physique des Particules de Marseille ( CPPM ), Centre National de la Recherche Scientifique ( CNRS ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Aix Marseille Université ( AMU ), Institut Pluridisciplinaire Hubert Curien ( IPHC ), Centre National de la Recherche Scientifique ( CNRS ) -Université de Strasbourg ( UNISTRA ), Institut de Physique Nucléaire de Lyon ( IPNL ), Université Claude Bernard Lyon 1 ( UCBL ), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Centre National de la Recherche Scientifique ( CNRS ), Laboratoire de l'Accélérateur Linéaire ( LAL ), Université Paris-Sud - Paris 11 ( UP11 ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Centre National de la Recherche Scientifique ( CNRS ), Laboratoire de Physique Subatomique et de Cosmologie ( LPSC ), Université Joseph Fourier - Grenoble 1 ( UJF ) -Institut polytechnique de Grenoble - Grenoble Institute of Technology ( Grenoble INP ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique ( CNRS ) -Université Grenoble Alpes ( UGA ), Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA), and Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])
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Top quark ,Q007TP ,top: mass: measured ,((n)jet dilepton) [final state] ,Tevatron ,pair production [top] ,01 natural sciences ,law.invention ,Physics, Particles & Fields ,High Energy Physics - Experiment ,High Energy Physics - Experiment (hep-ex) ,law ,DZERO ,[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex] ,Batavia TEVATRON Coll ,Nuclear Experiment ,Physics ,scattering [anti-p p] ,GLOBAL QCD ANALYSIS ,Detector ,ROOT-S=7 ,ATLAS ,Physical Sciences ,ComputingMethodologies_DOCUMENTANDTEXTPROCESSING ,mass: measured [top] ,top: pair production ,((n)jet lepton) [final state] ,Particle physics ,1800 GeV-cms1960 GeV-cms ,Astrophysics::High Energy Astrophysical Phenomena ,FOS: Physical sciences ,final state: ((n)jet lepton) ,Astronomy & Astrophysics ,anti-p p: colliding beams ,Nuclear physics ,EVENTS ,[ PHYS.HEXP ] Physics [physics]/High Energy Physics - Experiment [hep-ex] ,0103 physical sciences ,anti-p p: scattering ,ddc:530 ,Combined result ,High Energy Physics ,010306 general physics ,Collider ,DETECTOR ,Science & Technology ,PP COLLISIONS ,1960 GeV-cms ,010308 nuclear & particles physics ,final state: ((n)jet dilepton) ,hep-ex ,High Energy Physics::Phenomenology ,D0 experiment ,DIFFERENCE ,PARTON DISTRIBUTIONS ,Experimental High Energy Physics ,Physics::Accelerator Physics ,TEV ,High Energy Physics::Experiment ,1800 GeV-cms ,colliding beams [anti-p p] ,Lepton ,experimental results - Abstract
We present a combination of measurements of the top quark mass by the D0 experiment in the lepton+jets and dilepton channels. We use all the data collected in Run I (1992--1996) at $\sqrt s=1.8$ TeV and Run II (2001--2011) at $\sqrt s=1.96$ TeV of the Tevatron $p \bar{p}$ collider, corresponding to integrated luminosities of 0.1 fb$^{-1}$ and 9.7 fb$^{-1}$, respectively. The combined result is: $m_t = 174.95 \pm0.40\,{\rm(stat)} \pm 0.64\,{\rm(syst)}\,{\rm{GeV}}=174.95 \pm 0.75 \, {\rm{GeV}}$., 12 pages, 2 figure, published in Phys. Rev. D
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- 2017
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10. Disorganized somatotopy in the putamen of patients with focal hand dystonia
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M. Vidailhet, Christine Delmaire, Sophie Sangla, Sabine Meunier, Line Garnero, Emmanuel Gerardin, S. Tezenas du Montcel, Stéphane Lehéricy, J.-F. Mangin, Alexandre Krainik, Neuro-anatomie fonctionnelle du comportement et de ses troubles, Université Pierre et Marie Curie - Paris 6 ( UPMC ) -IFR70-Institut National de la Santé et de la Recherche Médicale ( INSERM ), Departement de neuroradiologie, CHU La Tronche, Neuroimagerie Fonctionnelle et Metabolique, Université Joseph Fourier - Grenoble 1 ( UJF ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ), Grenoble Institut des Neurosciences ( GIN ), Institut National de la Santé et de la Recherche Médicale ( INSERM ) -CHU Grenoble-Université Joseph Fourier - Grenoble 1 ( UJF ), Département de neuro-radiologie, Université Joseph Fourier - Grenoble 1 ( UJF ) -CHU Grenoble, Service de biostatistiques et information médicale [CHU Pitié-Salpêtrière], Assistance publique - Hôpitaux de Paris (AP-HP)-CHU Pitié-Salpêtrière [APHP], Génétique épidémiologique et structures des populations humaines ( Inserm U535 ), Epidémiologie, sciences sociales, santé publique ( IFR 69 ), Université Panthéon-Sorbonne ( UP1 ) -Université Paris-Sud - Paris 11 ( UP11 ) -École des hautes études en sciences sociales ( EHESS ) -Assistance publique - Hôpitaux de Paris (AP-HP)-Université Paris Descartes - Paris 5 ( UPD5 ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Centre National de la Recherche Scientifique ( CNRS ) -Université Panthéon-Sorbonne ( UP1 ) -Université Paris-Sud - Paris 11 ( UP11 ) -École des hautes études en sciences sociales ( EHESS ) -Assistance publique - Hôpitaux de Paris (AP-HP)-Université Paris Descartes - Paris 5 ( UPD5 ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Centre National de la Recherche Scientifique ( CNRS ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ), Institut Européen des membranes ( IEM ), Centre National de la Recherche Scientifique ( CNRS ) -Ecole Nationale Supérieure de Chimie de Montpellier ( ENSCM ) -Université Montpellier 2 - Sciences et Techniques ( UM2 ) -Université de Montpellier ( UM ), Physiologie et physiopathologie de la motricité chez l'homme, Neurobiologie des processus adaptatifs ( NPA ), Université Pierre et Marie Curie - Paris 6 ( UPMC ) -Centre National de la Recherche Scientifique ( CNRS ), Centre de Recherche en Neurobiologie cellulaire et moléculaire, Faculté de Médecine de Liège, Department of Physiology, Transnationale Universiteit Limburg/Limburgs, Center for Cellular and Molecular Neuroscience, Université de Liège, Laboratoire de Physique de l'Université de Bourgogne ( LPUB ), Université de Bourgogne ( UB ) -Centre National de la Recherche Scientifique ( CNRS ), Center for Neuroscience and Behavioral Medicine, Children's National Medical Center, Service de neurologie 1 [CHU Pitié-Salpétrière], Neurosciences cognitives et imagerie cérébrale ( NCIC ), Centre National de la Recherche Scientifique ( CNRS ), Service de neurologie [Univ. Paris VI], Université Pierre et Marie Curie - Paris 6 ( UPMC ) -Assistance publique - Hôpitaux de Paris (AP-HP)-CHU Saint-Antoine [APHP], Neurologie et thérapeutique expérimentale, Service de neuro-radiologie [CHU Pitié-Salpêtrière], Centre de Neuro-Imagerie de Recherche ( CENIR ), Université Pierre et Marie Curie - Paris 6 (UPMC)-IFR70-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Joseph Fourier - Grenoble 1 (UJF)-Institut National de la Santé et de la Recherche Médicale (INSERM), Grenoble Institut des Neurosciences (GIN), Université Joseph Fourier - Grenoble 1 (UJF)-CHU Grenoble, CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Génétique épidémiologique et structures des populations humaines (Inserm U535), Epidémiologie, sciences sociales, santé publique (IFR 69), Université Paris 1 Panthéon-Sorbonne (UP1)-Université Paris-Sud - Paris 11 (UP11)-École des hautes études en sciences sociales (EHESS)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris 1 Panthéon-Sorbonne (UP1)-Université Paris-Sud - Paris 11 (UP11)-École des hautes études en sciences sociales (EHESS)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Européen des membranes (IEM), Université Montpellier 2 - Sciences et Techniques (UM2)-Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Neurobiologie des processus adaptatifs (NPA), Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique de l'Université de Bourgogne (LPUB), Université de Bourgogne (UB)-Centre National de la Recherche Scientifique (CNRS), Neurosciences cognitives et imagerie cérébrale (NCIC), Centre National de la Recherche Scientifique (CNRS), CHU Saint-Antoine [AP-HP], Center for NeuroImaging Research-Human MRI Neuroimaging core facility for clinical research [ICM Paris] (CENIR), Institut du Cerveau = Paris Brain Institute (ICM), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Département de Biostatistique, Santé Publique et Information Médicale [CHU Pitié-Salpêtrière] (BIOSPIM ), Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Centre National de la Recherche Scientifique (CNRS)-Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Université Montpellier 2 - Sciences et Techniques (UM2)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM), Service de Neurologie [CHU Pitié-Salpêtrière], IFR70-CHU Pitié-Salpêtrière [AP-HP], Service de neurologie [Saint-Antoine], Université Pierre et Marie Curie - Paris 6 (UPMC)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Saint-Antoine [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR70-Université Pierre et Marie Curie - Paris 6 (UPMC), Service de Neuroradiologie [CHU Pitié-Salpêtrière], Centre de Neuro-Imagerie de Recherche (CENIR), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), CHU Grenoble-Université Joseph Fourier - Grenoble 1 (UJF), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Université Montpellier 2 - Sciences et Techniques (UM2)-Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service de neurologie [CHU Saint-Antoine], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute (ICM), Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], and Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)
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Male ,MESH : Lip ,MESH : Brain Mapping ,MESH : Aged ,Striatum ,Neurological disorder ,Brain mapping ,Functional Laterality ,MESH: Magnetic Resonance Imaging ,MESH: Putamen ,0302 clinical medicine ,MESH : Neural Pathways ,Neural Pathways ,MESH : Female ,MESH: Arm ,MESH: Brain Mapping ,Dystonia ,Cerebral Cortex ,MESH: Aged ,0303 health sciences ,Brain Mapping ,MESH: Middle Aged ,Putamen ,Anatomy ,MESH: Lip ,MESH : Hand ,Middle Aged ,MESH : Adult ,Magnetic Resonance Imaging ,MESH: Predictive Value of Tests ,medicine.anatomical_structure ,Cerebral cortex ,Dystonic Disorders ,Arm ,MESH : Cerebral Cortex ,Female ,Adult ,MESH : Male ,MESH : Arm ,MESH: Hand ,Central nervous system disease ,03 medical and health sciences ,MESH : Dystonic Disorders ,Predictive Value of Tests ,MESH : Magnetic Resonance Imaging ,medicine ,Humans ,MESH : Middle Aged ,MESH: Functional Laterality ,MESH : Predictive Value of Tests ,MESH : Functional Laterality ,030304 developmental biology ,Aged ,MESH: Humans ,[SDV.BA.MVSA]Life Sciences [q-bio]/Animal biology/Veterinary medicine and animal Health ,business.industry ,MESH: Neural Pathways ,MESH : Humans ,MESH: Dystonic Disorders ,MESH: Adult ,medicine.disease ,Hand ,Lip ,MESH: Male ,MESH: Cerebral Cortex ,nervous system ,MESH : Putamen ,Neurology (clinical) ,[ SDV.BA.MVSA ] Life Sciences [q-bio]/Animal biology/Veterinary medicine and animal Health ,business ,MESH: Female ,030217 neurology & neurosurgery ,Dystonic disorder - Abstract
International audience; OBJECTIVE: To explore the selectivity of neuronal somatotopic representation in the striatum of patients with unilateral task-specific dystonia of the right arm. MATERIALS AND METHODS: The authors used fMRI in 14 right-handed dystonic subjects to examine putaminal organization. Subjects performed flexion/extension of the right and left fingers and toes, and contraction of the lips. RESULTS: Compared to healthy volunteer subjects, dystonic subjects had altered somatotopic organization in the left putamen, contralateral to the affected hand. Disease severity correlated with underactivation and decreased distance between right hand and lip representations. In the right putamen, ipsilateral to the affected hand, the somatotopic organization was not altered but disease severity also correlated with reduced distances between limbs. CONCLUSION: In dystonia there may be a dedifferentiation of the normally segregated cortico-subcortical sensorimotor maps in the putamen, which may contribute to the loss of functional selectivity of muscle activity observed in these dystonic subjects.
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- 2005
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11. LABORATORY SIMULATION FOR HEAVY METAL EVOLUTION IN CSO POLLUTED RIVER SEINE SEDIMENTS AND INTERSTITIAL WATERS
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Comblez, Anne, Bussy, Anne-Laure, Mouchel, Jean-Marie, Thévenot, Daniel R., Laboratoire de Bioélectrochimie et Analyse du Milieu (LABAM), Université Paris-Est Marne-la-Vallée (UPEM)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Université Pierre et Marie Curie - Paris 6 (UPMC), CERGRENE (CERGRENE), Ecole Nationale du Génie Rural, des Eaux et des Forêts (ENGREF)-École des Ponts ParisTech (ENPC), Thevenot, Daniel, and PIREN-Seine, CNRS GDR 1067, LGA, Univ. Paris VI
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[SDE.MCG] Environmental Sciences/Global Changes ,[SDE.MCG]Environmental Sciences/Global Changes ,[CHIM] Chemical Sciences ,[CHIM]Chemical Sciences ,heavy metals ,combined sewer overflow CSO ,river sediment ,diagenesis - Abstract
International audience; The River Seine is a very small stream, compared to the important population and the numerous activities of the district of Paris which have grown within its basin. It is now strongly constrained by anthropogenic influences such as dams, reservoirs, or sewage work outlets. Yet, a notable part of the wastes, produced within the basin is directly discharged into the river.In order to assess the impact of such urban...
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- 1996
12. Re: The Effect of Laser Fiber Cleave Technique and Lithotripsy Time on Power Output.
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Haddad M, Emiliani E, and Traxer O
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- Humans, Lasers, Lithotripsy, Lithotripsy, Laser
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- 2021
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13. Clinical Features and Diagnosis of Anterior Segment Inflammation Related to Cytomegalovirus in Immunocompetent African, Asian, and Caucasian Patients.
- Author
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Leleu I, Jhanji V, Touhami S, Westcott M, Angi M, Titah C, Rousseau A, Hamard P, Brasnu E, Manicom T, Blumen-Ohana E, Rozenberg F, Vauloup-Fellous C, Deback C, Labetoulle M, Sahel JA, Bodaghi B, Merabet L, Kobal A, Brignole-Baudouin F, and Errera MH
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Antiviral Agents therapeutic use, Aqueous Humor virology, Child, Cytomegalovirus genetics, Cytomegalovirus Infections ethnology, Cytomegalovirus Infections immunology, DNA, Viral analysis, Eye Infections, Viral ethnology, Eye Infections, Viral immunology, Female, Follow-Up Studies, France epidemiology, Ganciclovir therapeutic use, Humans, Incidence, Male, Middle Aged, Retrospective Studies, United States epidemiology, Uveitis, Anterior ethnology, Uveitis, Anterior immunology, Valganciclovir therapeutic use, Young Adult, Black or African American, Asian People, Black People, Cytomegalovirus Infections diagnosis, Eye Infections, Viral diagnosis, Immunocompromised Host, Uveitis, Anterior diagnosis, White People
- Abstract
Objective : To report the clinical features and treatment outcomes in immunocompetent patients with anterior segment inflammation (ASI) related to human cytomegalovirus (HCMV) depending on their ethnic origin. Material and Methods : Multicenter retrospective study of 38 patients with at least one test, either HCMV-positive PCR or GWc. Results : Features of Posner-Schlossman syndrome were observed in 50% of the eyes, Fuchs heterochromic iridocyclitis in 13% of the eyes, chronic nonspecific anterior uveitis in 21% of the eyes, and corneal endotheliitis in 18% of the eyes. PCR and GWc were positive for HCMV in 50% and 96.2% of the eyes, respectively. Glaucoma was diagnosed in 50% of eyes. Treatment was oral valganciclovir in about half of the patients. Other treatments were intravenous ganciclovir and/or ganciclovir topical ointment and/or intravitreal ganciclovir. Conclusions : No obvious association of specific clinical features with individual ethnicity could be identified. We found a high rate of glaucoma in all ethnic groups. There was a delay in diagnosis and specific treatment of HCMV in most patients.
- Published
- 2021
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14. A Comparison of the Dexamethasone Implant (Ozurdex®) and Inferior Fornix-Based Sub-Tenon Triamcinolone Acetonide for Treatment of Inflammatory Ocular Diseases.
- Author
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Errera MH, Westcott M, Benesty J, Falah S, Smadja J, Orès R, Pratas AC, Sedira N, Bensemlali A, Héron E, Goldschmidt P, Bodaghi B, and Sahel JA
- Subjects
- Adult, Aged, Drug Implants, Female, Follow-Up Studies, Glucocorticoids administration & dosage, Humans, Injections, Intraocular, Male, Middle Aged, Retrospective Studies, Tenon Capsule, Time Factors, Tomography, Optical Coherence, Treatment Outcome, Uveitis diagnosis, Dexamethasone administration & dosage, Triamcinolone Acetonide administration & dosage, Uveitis drug therapy, Visual Acuity
- Abstract
Purpose: To evaluate the efficacy and safety of dexamethasone (DEX) implant compared with inferior fornix-based sub-Tenon triamcinolone injection (PSTA) for treatment of uveitis., Methods: A total of 48 eyes received DEX and 49 eyes received PSTA as the first treatment., Results: A total of 31 eyes were implanted with DEX relapsed (64.5%) after the first injection, while 32 eyes were injected with PSTA as the first treatment relapsed (65.3%). Kaplan-Meier estimated survival to overall relapse after the first injection was a mean 20 months± 3.6 months for DEX (median,7) and 14 months± 1.9 months (median,9) for the PSTA (P = 0.505). Of 49 eyes receiving the PSTA implant as the first treatment, inflammation persisted in 14.3% after the first injection but persisted in none after the DEX injection (P = 0.005)., Conclusions: DEX implantation achieved a higher rate of disease control in the initial 12 weeks postinjection with a relative equivalence in the duration of effect and relapse rates when compared with PSTA.
- Published
- 2019
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15. Mechanistic basis of an epistatic interaction reducing age at onset in hereditary spastic paraplegia.
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Newton T, Allison R, Edgar JR, Lumb JH, Rodger CE, Manna PT, Rizo T, Kohl Z, Nygren AOH, Arning L, Schüle R, Depienne C, Goldberg L, Frahm C, Stevanin G, Durr A, Schöls L, Winner B, Beetz C, and Reid E
- Subjects
- Adult, Age of Onset, CD8 Antigens genetics, CD8 Antigens metabolism, DNA-Binding Proteins genetics, DNA-Binding Proteins metabolism, Female, Guanine Nucleotide Exchange Factors genetics, Guanine Nucleotide Exchange Factors metabolism, HeLa Cells metabolism, HeLa Cells ultrastructure, Humans, Lysosomal-Associated Membrane Protein 1 metabolism, Lysosomal-Associated Membrane Protein 1 ultrastructure, Lysosomes metabolism, Lysosomes ultrastructure, Male, Membrane Proteins genetics, Membrane Proteins metabolism, Middle Aged, Nuclear Proteins metabolism, Nuclear Proteins ultrastructure, Protein Transport genetics, Transcription Factors genetics, Transcription Factors metabolism, Epistasis, Genetic genetics, Mutation genetics, Nuclear Proteins genetics, Spastic Paraplegia, Hereditary genetics, Spastin genetics
- Abstract
Many genetic neurological disorders exhibit variable expression within affected families, often exemplified by variations in disease age at onset. Epistatic effects (i.e. effects of modifier genes on the disease gene) may underlie this variation, but the mechanistic basis for such epistatic interactions is rarely understood. Here we report a novel epistatic interaction between SPAST and the contiguous gene DPY30, which modifies age at onset in hereditary spastic paraplegia, a genetic axonopathy. We found that patients with hereditary spastic paraplegia caused by genomic deletions of SPAST that extended into DPY30 had a significantly younger age at onset. We show that, like spastin, the protein encoded by SPAST, the DPY30 protein controls endosomal tubule fission, traffic of mannose 6-phosphate receptors from endosomes to the Golgi, and lysosomal ultrastructural morphology. We propose that additive effects on this pathway explain the reduced age at onset of hereditary spastic paraplegia in patients who are haploinsufficient for both genes.
- Published
- 2018
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16. Neuropathology of iatrogenic Creutzfeldt-Jakob disease and immunoassay of French cadaver-sourced growth hormone batches suggest possible transmission of tauopathy and long incubation periods for the transmission of Abeta pathology.
- Author
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Duyckaerts C, Sazdovitch V, Ando K, Seilhean D, Privat N, Yilmaz Z, Peckeu L, Amar E, Comoy E, Maceski A, Lehmann S, Brion JP, Brandel JP, and Haïk S
- Subjects
- Adult, Amyloid beta-Peptides metabolism, Brain metabolism, Cadaver, Cohort Studies, Creutzfeldt-Jakob Syndrome metabolism, France, Humans, Iatrogenic Disease, Immunoassay, Infectious Disease Incubation Period, Prion Proteins genetics, Prion Proteins metabolism, Young Adult, tau Proteins metabolism, Brain pathology, Creutzfeldt-Jakob Syndrome pathology, Creutzfeldt-Jakob Syndrome transmission, Drug Contamination, Human Growth Hormone administration & dosage
- Abstract
Abeta deposits and tau pathology were investigated in 24 French patients that died from iatrogenic Creutzfeldt-Jakob disease after exposure to cadaver-derived human growth hormone (c-hGH) in the 1980s. Abeta deposits were found only in one case that had experienced one of the longest incubation periods. Three cases had also intracellular tau accumulation. The analysis of 24 batches of c-hGH, produced between 1974 and 1988, demonstrated for the first time the presence of Abeta and tau contaminants in c-hGH (in 17 and 6 batches, respectively). The incubation of prion disease was shorter in the French patients than the incubation times reported in two previously published British series. We interpreted the low incidence of Abeta in this French series as a consequence of the shorter incubation period observed in France, as compared to that observed in the United Kingdom. This concept suggested that a mean incubation period for the development of detectable Abeta deposits would be longer than 18 years after the first exposure. Moreover, we hypothesized that tau pathology might also be transmissible in humans.
- Published
- 2018
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17. Iatrogenic Creutzfeldt-Jakob disease with Amyloid-β pathology: an international study.
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Cali I, Cohen ML, Haik S, Parchi P, Giaccone G, Collins SJ, Kofskey D, Wang H, McLean CA, Brandel JP, Privat N, Sazdovitch V, Duyckaerts C, Kitamoto T, Belay ED, Maddox RA, Tagliavini F, Pocchiari M, Leschek E, Appleby BS, Safar JG, Schonberger LB, and Gambetti P
- Subjects
- Adult, Age Factors, Aged, Alzheimer Disease metabolism, Alzheimer Disease pathology, Brain metabolism, Cerebral Amyloid Angiopathy metabolism, Cerebral Amyloid Angiopathy pathology, Cohort Studies, Creutzfeldt-Jakob Syndrome metabolism, Encephalopathy, Bovine Spongiform metabolism, Female, Humans, Iatrogenic Disease, Internationality, Male, Middle Aged, Plaque, Amyloid metabolism, Plaque, Amyloid pathology, PrPSc Proteins metabolism, Severity of Illness Index, Young Adult, tau Proteins metabolism, Amyloid beta-Peptides metabolism, Brain pathology, Creutzfeldt-Jakob Syndrome pathology, Encephalopathy, Bovine Spongiform pathology
- Abstract
The presence of pathology related to the deposition of amyloid-β (Aβ) has been recently reported in iatrogenic Creutzfeldt-Jakob disease (iCJD) acquired from inoculation of growth hormone (GH) extracted from human cadaveric pituitary gland or use of cadaveric dura mater (DM) grafts.To investigate this phenomenon further, a cohort of 27 iCJD cases - 21 with adequate number of histopathological sections - originating from Australia, France, Italy, and the Unites States, were examined by immunohistochemistry, amyloid staining, and Western blot analysis of the scrapie prion protein (PrP
Sc ), and compared with age-group matched cases of sporadic CJD (sCJD), Alzheimer disease (AD) or free of neurodegenerative diseases (non-ND).Cases of iCJD and sCJD shared similar profiles of proteinase K-resistant PrPSc with the exception of iCJD harboring the "MMi" phenotype. Cerebral amyloid angiopathy (CAA), either associated with, or free of, Thioflavin S-positive amyloid core plaques (CP), was observed in 52% of 21 cases of iCJD, which comprised 37.5% and 61.5% of the cases of GH- and DM-iCJD, respectively. If only cases younger than 54 years were considered, Aβ pathology affected 41%, 2% and 0% of iCJD, sCJD and non-ND, respectively. Despite the patients' younger age CAA was more severe in iCJD than sCJD, while Aβ diffuse plaques, in absence of Aβ CP, populated one third of sCJD. Aβ pathology was by far most severe in AD. Tau pathology was scanty in iCJD and sCJD.In conclusion, (i) despite the divergences in the use of cadaveric GH and DM products, our cases combined with previous studies showed remarkably similar iCJD and Aβ phenotypes indicating that the occurrence of Aβ pathology in iCJD is a widespread phenomenon, (ii) CAA emerges as the hallmark of the Aβ phenotype in iCJD since it is observed in nearly 90% of all iCJD with Aβ pathology reported to date including ours, and it is shared by GH- and DM-iCJD, (iii) although the contributions to Aβ pathology of other factors, including GH deficiency, cannot be discounted, our findings increase the mounting evidence that this pathology is acquired by a mechanism resembling that of prion diseases.- Published
- 2018
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18. Ion Channel Trafficking: Control of Ion Channel Density as a Target for Arrhythmias?
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Balse E and Boycott HE
- Abstract
The shape of the cardiac action potential (AP) is determined by the contributions of numerous ion channels. Any dysfunction in the proper function or expression of these ion channels can result in a change in effective refractory period (ERP) and lead to arrhythmia. The processes underlying the correct targeting of ion channels to the plasma membrane are complex, and have not been fully characterized in cardiac myocytes. Emerging evidence highlights ion channel trafficking as a potential causative factor in certain acquired and inherited arrhythmias, and therapies which target trafficking as opposed to pore block are starting to receive attention. In this review we present the current evidence for the mechanisms which underlie precise control of cardiac ion channel trafficking and targeting.
- Published
- 2017
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19. Impact of the Curve Diameter and Laser Settings on Laser Fiber Fracture.
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Haddad M, Emiliani E, Rouchausse Y, Coste F, Doizi S, Berthe L, Butticé S, Somani B, and Traxer O
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- Humans, Laser Therapy, Equipment Design, Lasers, Solid-State therapeutic use, Lithotripsy, Laser instrumentation, Ureteral Calculi therapy, Ureteroscopes
- Abstract
Objective: To analyze the risk factors for laser fiber fractures when deflected to form a curve, including laser settings, size of the laser fiber, and the fiber bending diameter., Materials and Methods: Single-use 272 and 365 μm fibers (Rocamed
® , Monaco) were employed along with a holmium laser (Rocamed). Five different fiber curve diameters were tested: 9, 12, 15, 18, and 20 mm. Fragmentation and dusting settings were used at a theoretical power of 7.5 W. The laser was activated for 5 minutes and the principal judgment criterion was fiber fracture. Every test for each parameter, bending diameter, and fiber size combinations was repeated 10 times., Results: With dusting settings, fibers broke more frequently at a curved diameter of 9 mm for both 272 and 365 μm fibers (p = 0.037 and 0.006, respectively). Using fragmentation settings, fibers broke more frequently at 12 mm for 272 μm and 15 mm for 365 μm (p = 0.007 and 0.033, respectively). Short pulse and high energy were significant risk factors for fiber fracture using the 365 μm fibers (p = 0.02), but not for the 272 μm fibers (p = 0.35). Frequency was not a risk factor for fiber rupture. Fiber diameters also seemed to be involved in the failure with a higher number of broken fibers for the 365 μm fibers, but this was not statistically significant when compared with the 272 μm fibers (p > 0.05)., Conclusion: Small-core fibers are more resistant than large-core fibers as lower bending diameters (<9 mm) are required to break smaller fibers. In acute angles, the use of small-core fibers, at a low energy and long-pulse (dusting) setting, will reduce the risk of fiber rupture.- Published
- 2017
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20. Detection and partial discrimination of atypical and classical bovine spongiform encephalopathies in cattle and primates using real-time quaking-induced conversion assay.
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Levavasseur E, Biacabe AG, Comoy E, Culeux A, Grznarova K, Privat N, Simoneau S, Flan B, Sazdovitch V, Seilhean D, Baron T, and Haïk S
- Subjects
- Animals, Brain pathology, Brain Chemistry, Cattle, Creutzfeldt-Jakob Syndrome diagnosis, Creutzfeldt-Jakob Syndrome pathology, Humans, Recombinant Proteins analysis, Sensitivity and Specificity, Creutzfeldt-Jakob Syndrome veterinary, Encephalopathy, Bovine Spongiform diagnosis, Encephalopathy, Bovine Spongiform pathology, Primate Diseases diagnosis, Prion Proteins analysis
- Abstract
The transmission of classical bovine spongiform encephalopathy (C-BSE) through contaminated meat product consumption is responsible for variant Creutzfeldt-Jakob disease (vCJD) in humans. More recent and atypical forms of BSE (L-BSE and H-BSE) have been identified in cattle since the C-BSE epidemic. Their low incidence and advanced age of onset are compatible with a sporadic origin, as are most cases of Creutzfeldt-Jakob disease (CJD) in humans. Transmissions studies in primates and transgenic mice expressing a human prion protein (PrP) indicated that atypical forms of BSE may be associated with a higher zoonotic potential than classical BSE, and require particular attention for public health. Recently, methods designed to amplify misfolded forms of PrP have emerged as promising tools to detect prion strains and to study their diversity. Here, we validated real-time quaking-induced conversion assay for the discrimination of atypical and classical BSE strains using a large series of bovine samples encompassing all the atypical BSE cases detected by the French Centre of Reference during 10 years of exhaustive active surveillance. We obtained a 100% sensitivity and specificity for atypical BSE detection. In addition, the assay was able to discriminate atypical and classical BSE in non-human primates, and also sporadic CJD and vCJD in humans. The RT-QuIC assay appears as a practical means for a reliable detection of atypical BSE strains in a homologous or heterologous PrP context.
- Published
- 2017
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21. Arsenate reductase from Thermus thermophilus conjugated to polyethylene glycol-stabilized gold nanospheres allow trace sensing and speciation of arsenic ions.
- Author
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Politi J, Spadavecchia J, Fiorentino G, Antonucci I, and De Stefano L
- Subjects
- Enzymes, Immobilized chemistry, Arsenate Reductases chemistry, Arsenic analysis, Bacterial Proteins chemistry, Biosensing Techniques methods, Gold chemistry, Metal Nanoparticles chemistry, Polyethylene Glycols chemistry, Thermus thermophilus enzymology
- Abstract
Water sources pollution by arsenic ions is a serious environmental problem all around the world. Arsenate reductase enzyme (TtArsC) from Thermus thermophilus extremophile bacterium, naturally binds arsenic ions, As(V) and As (III), in aqueous solutions. In this research, TtArsC enzyme adsorption onto hybrid polyethylene glycol-stabilized gold nanoparticles (AuNPs) was studied at different pH values as an innovative nanobiosystem for metal concentration monitoring. Characterizations were performed by UV/Vis and circular dichroism spectroscopies, TEM images and in terms of surface charge changes. The molecular interaction between arsenic ions and the TtArsC-AuNPs nanobiosystem was also monitored at all pH values considered by UV/Vis spectroscopy. Tests performed revealed high sensitivities and limits of detection equal to 10 ± 3 M
-12 and 7.7 ± 0.3 M-12 for As(III) and As(V), respectively., (© 2016 The Author(s).)- Published
- 2016
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22. Atomic and electronic structure of trilayer graphene/SiC(0001): Evidence of Strong Dependence on Stacking Sequence and charge transfer.
- Author
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Pierucci D, Brumme T, Girard JC, Calandra M, Silly MG, Sirotti F, Barbier A, Mauri F, and Ouerghi A
- Abstract
The transport properties of few-layer graphene are the directly result of a peculiar band structure near the Dirac point. Here, for epitaxial graphene grown on SiC, we determine the effect of charge transfer from the SiC substrate on the local density of states (LDOS) of trilayer graphene using scaning tunneling microscopy/spectroscopy and angle resolved photoemission spectroscopy (ARPES). Different spectra are observed and are attributed to the existence of two stable polytypes of trilayer: Bernal (ABA) and rhomboedreal (ABC) staking. Their electronic properties strongly depend on the charge transfer from the substrate. We show that the LDOS of ABC stacking shows an additional peak located above the Dirac point in comparison with the LDOS of ABA stacking. The observed LDOS features, reflecting the underlying symmetry of the two polytypes, were reproduced by explicit calculations within density functional theory (DFT) including the charge transfer from the substrate. These findings demonstrate the pronounced effect of stacking order and charge transfer on the electronic structure of trilayer or few layer graphene. Our approach represents a significant step toward understand the electronic properties of graphene layer under electrical field.
- Published
- 2016
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23. Primary CNS lymphoma at first relapse/progression: characteristics, management, and outcome of 256 patients from the French LOC network.
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Langner-Lemercier S, Houillier C, Soussain C, Ghesquières H, Chinot O, Taillandier L, Soubeyran P, Lamy T, Morschhauser F, Benouaich-Amiel A, Ahle G, Moles-Moreau MP, Moluçon-Chabrot C, Bourquard P, Damaj G, Jardin F, Larrieu D, Gyan E, Gressin R, Jaccard A, Choquet S, Brion A, Casasnovas O, Colin P, Reman O, Tempescul A, Marolleau JP, Fabbro M, Naudet F, Hoang-Xuan K, and Houot R
- Subjects
- Adult, Aged, Aged, 80 and over, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Central Nervous System Neoplasms pathology, Combined Modality Therapy, Disease Progression, Female, Hematopoietic Stem Cell Transplantation, Humans, Lymphoma, Non-Hodgkin pathology, Male, Middle Aged, Neoplasm Recurrence, Local pathology, Neoplasm Staging, Prognosis, Prospective Studies, Survival Rate, Transplantation, Autologous, Central Nervous System Neoplasms therapy, Drug Resistance, Neoplasm, Lymphoma, Non-Hodgkin therapy, Neoplasm Recurrence, Local therapy, Salvage Therapy
- Abstract
Background: Treatment of relapsed/refractory (R/R) primary CNS lymphoma (PCNSL) is poorly defined, because randomized trials and large studies are lacking. The aim of this study was to analyze the characteristics, management, and outcome of R/R PCNSL patients after first-line therapy in a nationwide cohort., Methods: We analyzed R/R PCNSL patients following first-line treatment who had been prospectively registered in the database of the French network for oculocerebral lymphoma (LOC) between 2011 and 2014., Results: Among 563 PCNSL patients treated with first-line therapy, we identified 256 with relapsed (n = 93, 16.5%) or refractory (n = 163, 29.0%) disease. Patients who were asymptomatic at relapse/progression (25.5%), mostly diagnosed on routine follow-up neuroimaging, tended to have a better outcome. Patients who received salvage therapy followed by consolidation (mostly intensive chemotherapy plus autologous hematopoietic stem cell transplantation [ICT + AHSCT]) experienced prolonged survival compared with those who did not receive salvage or consolidation therapy. Independent prognostic factors at first relapse/progression were: KPS ≥ 70 vs KPS < 70), sensitivity to first-line therapy (relapsed vs refractory disease), duration of first remission (progression-free survival [PFS] ≥1 y vs <1 y), and management at relapse/progression (palliative care vs salvage therapy). Patients who relapsed early after first-line therapy (ie, PFS < 1 y) had a poor outcome, comparable to that of refractory patients. Conversely, patients experiencing late relapses (PFS ≥ 1 y) and/or undergoing consolidation with ICT + AHSCT experienced prolonged survival., Conclusions: About a third of PCNSL patients are primary refractory to first line treatment. We identified several independent prognostic factors that can guide the management of R/R PCNSL patients., (© The Author(s) 2016. Published by Oxford University Press on behalf of the Society for Neuro-Oncology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
- Published
- 2016
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24. Tunable Design of Gold(III)-Doxorubicin Complex-PEGylated Nanocarrier. The Golden Doxorubicin for Oncological Applications.
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Moustaoui H, Movia D, Dupont N, Bouchemal N, Casale S, Djaker N, Savarin P, Prina-Mello A, de la Chapelle ML, and Spadavecchia J
- Subjects
- Antineoplastic Agents, Cell Line, Tumor, Doxorubicin, Drug Carriers, Drug Liberation, Humans, Nanostructures, Polyethylene Glycols, Gold chemistry
- Abstract
To date, the translation of Au (III) complexes into chemotherapeutic agents has been hindered by their low stability under physiological conditions, a crucial parameter in drug development. In this study, we report an innovative four-step synthesis of a stable Au (III)-doxorubicin (DOX) complex, acting as a key constitutive component of doxorubicin-loaded PEG-coated nanoparticles (DOX IN-PEG-AuNPs). For therapeutic purposes, such AuNPs were then functionalized with the anti-Kv11.1 polyclonal antibody (pAb), which specifically recognizes the hERG1 channel that is overexpressed on the membrane of human pancreatic cancer cells. The nature of the interactions between DOX and Au (III) ions was probed by various analytical techniques (Raman spectroscopy, UV-vis, and (1)H NMR), which enabled studying the Au (III)-DOX interactions during AuNPs formation. The theoretical characterization of the vibrational bands and the electronic transitions of the Au (III)-DOX complex calculated through computational studies showed significant qualitative agreement with the experimental observations on AuNPs samples. Stability in physiological conditions and efficient drug loading (up to to 85 w/w %) were achieved, while drug release was strongly dependent on the structure of DOX IN-PEG-AuNPs and on the pH. Furthermore, the interactions among DOX, PEG, and Au (III) ions in DOX IN-PEG-AuNPs differed significantly from those found in polymer-modified AuNPs loaded with DOX by covalent linkage, referred to as DOX ON-PEG-AuNPs. In vitro experiments indeed demonstrated that such differences strongly influenced the therapeutic potential of AuNPs in pancreatic cancer treatment, with a significant increase of the DOX therapeutic index when complexed to Au (III) ions. Collectively, our study demonstrated that Au (III)-DOX complexes as building blocks of PEGylated AuNPs constitutes a promising approach to transform promising Au (III) complexes into real chemotherapeutic drugs for the treatment of pancreatic cancer.
- Published
- 2016
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25. Targeted polyethylene glycol gold nanoparticles for the treatment of pancreatic cancer: from synthesis to proof-of-concept in vitro studies.
- Author
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Spadavecchia J, Movia D, Moore C, Maguire CM, Moustaoui H, Casale S, Volkov Y, and Prina-Mello A
- Subjects
- Antibiotics, Antineoplastic chemistry, Apoptosis drug effects, Blotting, Western, Cell Proliferation drug effects, Doxorubicin chemistry, Drug Carriers therapeutic use, Humans, In Vitro Techniques, Metal Nanoparticles chemistry, Pancreatic Neoplasms pathology, Tumor Cells, Cultured, Antibiotics, Antineoplastic administration & dosage, Doxorubicin administration & dosage, Drug Delivery Systems, Gold chemistry, Metal Nanoparticles administration & dosage, Pancreatic Neoplasms drug therapy, Polyethylene Glycols chemistry
- Abstract
The main objective of this study was to optimize and characterize a drug delivery carrier for doxorubicin, intended to be intravenously administered, capable of improving the therapeutic index of the chemotherapeutic agent itself, and aimed at the treatment of pancreatic cancer. In light of this goal, we report a robust one-step method for the synthesis of dicarboxylic acid-terminated polyethylene glycol (PEG)-gold nanoparticles (AuNPs) and doxorubicin-loaded PEG-AuNPs, and their further antibody targeting (anti-Kv11.1 polyclonal antibody [pAb]). In in vitro proof-of-concept studies, we evaluated the influence of the nanocarrier and of the active targeting functionality on the anti-tumor efficacy of doxorubicin, with respect to its half-maximal effective concentration (EC50) and drug-triggered changes in the cell cycle. Our results demonstrated that the therapeutic efficacy of doxorubicin was positively influenced not only by the active targeting exploited through anti-Kv11.1-pAb but also by the drug coupling with a nanometer-sized delivery system, which indeed resulted in a 30-fold decrease of doxorubicin EC50, cell cycle blockage, and drug localization in the cell nuclei. The cell internalization pathway was strongly influenced by the active targeting of the Kv11.1 subunit of the human Ether-à-go-go related gene 1 (hERG1) channel aberrantly expressed on the membrane of pancreatic cancer cells. Targeted PEG-AuNPs were translocated into the lysosomes and were associated to an increased lysosomal function in PANC-1 cells. Additionally, doxorubicin release into an aqueous environment was almost negligible after 7 days, suggesting that drug release from PEG-AuNPs was triggered by enzymatic activity. Although preliminary, data gathered from this study have considerable potential in the application of safe-by-design nano-enabled drug-delivery systems (ie, nanomedicines) for the treatment of pancreatic cancer, a disease with a poor prognosis and one of the main current burdens of today's health care bill of industrialized countries.
- Published
- 2016
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26. Littoral lichens as a novel source of potentially bioactive Actinobacteria.
- Author
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Parrot D, Antony-Babu S, Intertaglia L, Grube M, Tomasi S, and Suzuki MT
- Subjects
- Actinobacteria classification, Actinobacteria isolation & purification, Biodiversity, Cluster Analysis, Lichens classification, Lichens isolation & purification, Phylogeny, Polyketide Synthases genetics, Polyketide Synthases metabolism, Polymerase Chain Reaction, RNA, Ribosomal, 16S genetics, RNA, Ribosomal, 16S metabolism, Sequence Analysis, DNA, Soil Microbiology, Actinobacteria genetics, Lichens genetics
- Abstract
Cultivable Actinobacteria are the largest source of microbially derived bioactive molecules. The high demand for novel antibiotics highlights the need for exploring novel sources of these bacteria. Microbial symbioses with sessile macro-organisms, known to contain bioactive compounds likely of bacterial origin, represent an interesting and underexplored source of Actinobacteria. We studied the diversity and potential for bioactive-metabolite production of Actinobacteria associated with two marine lichens (Lichina confinis and L. pygmaea; from intertidal and subtidal zones) and one littoral lichen (Roccella fuciformis; from supratidal zone) from the Brittany coast (France), as well as the terrestrial lichen Collema auriforme (from a riparian zone, Austria). A total of 247 bacterial strains were isolated using two selective media. Isolates were identified and clustered into 101 OTUs (98% identity) including 51 actinobacterial OTUs. The actinobacterial families observed were: Brevibacteriaceae, Cellulomonadaceae, Gordoniaceae, Micrococcaceae, Mycobacteriaceae, Nocardioidaceae, Promicromonosporaceae, Pseudonocardiaceae, Sanguibacteraceae and Streptomycetaceae. Interestingly, the diversity was most influenced by the selective media rather than lichen species or the level of lichen thallus association. The potential for bioactive-metabolite biosynthesis of the isolates was confirmed by screening genes coding for polyketide synthases types I and II. These results show that littoral lichens are a source of diverse potentially bioactive Actinobacteria.
- Published
- 2015
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27. Interaction of Thermus thermophilus ArsC enzyme and gold nanoparticles naked-eye assays speciation between As(III) and As(V).
- Author
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Politi J, Spadavecchia J, Fiorentino G, Antonucci I, Casale S, and De Stefano L
- Subjects
- Arsenate Reductases genetics, Arsenate Reductases metabolism, Bacterial Proteins genetics, Bacterial Proteins metabolism, Ions chemistry, Microscopy, Electron, Transmission, Particle Size, Polyethylene Glycols chemistry, Recombinant Proteins biosynthesis, Recombinant Proteins chemistry, Recombinant Proteins isolation & purification, Spectrophotometry, Ultraviolet, Spectroscopy, Fourier Transform Infrared, Surface Plasmon Resonance, Arsenate Reductases chemistry, Arsenic chemistry, Bacterial Proteins chemistry, Gold chemistry, Metal Nanoparticles chemistry, Thermus thermophilus enzymology
- Abstract
The thermophilic bacterium Thermus thermophilus HB27 encodes chromosomal arsenate reductase (TtArsC), the enzyme responsible for resistance to the harmful effects of arsenic. We report on adsorption of TtArsC onto gold nanoparticles for naked-eye monitoring of biomolecular interaction between the enzyme and arsenic species. Synthesis of hybrid biological-metallic nanoparticles has been characterized by transmission electron microscopy (TEM), ultraviolet-visible (UV-vis), dynamic light scattering (DLS) and phase modulated infrared reflection absorption (PM-IRRAS) spectroscopies. Molecular interactions have been monitored by UV-vis and Fourier transform-surface plasmon resonance (FT-SPR). Due to the nanoparticles' aggregation on exposure to metal salts, pentavalent and trivalent arsenic solutions can be clearly distinguished by naked-eye assay, even at 85 μM concentration. Moreover, the assay shows partial selectivity against other heavy metals.
- Published
- 2015
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28. An investigation of prior knowledge in Automatic Music Transcription systems.
- Author
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Cazau D, Revillon G, Krywyk J, and Adam O
- Abstract
Automatic transcription of music is a long-studied research field with many operational systems available commercially. In this paper, a generic transcription system able to host various prior knowledge parameters has been developed, followed by an in-depth investigation of their impact on music transcription. Explicit links between musical knowledge and algorithmic formalism have been made. Musical knowledge covers classes of timbre, musicology, and playing style of an instrument repertoire. An evaluation sound corpus gathering musical pieces played by human performers from three different instrument repertoires, namely, classical piano, steel-string acoustic guitar, and the marovany zither from Madagascar, has been developed. The different components of musical knowledge have been successively incorporated in a complete transcription system, consisting mainly of a Probabilistic Latent Component Analysis algorithm post-processed with a Hidden Markov Model, and their impact on transcription results have been comparatively evaluated.
- Published
- 2015
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29. Long-term efficacy and safety of cladribine (2-CdA) in adult patients with mastocytosis.
- Author
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Barete S, Lortholary O, Damaj G, Hirsch I, Chandesris MO, Elie C, Hamidou M, Durieu I, Suarez F, Grosbois B, Limal N, Gyan E, Larroche C, Guillet G, Kahn JE, Casassus P, Amazzough K, Coignard-Biehler H, Georgin-Lavialle S, Lhermitte L, Fraitag S, Canioni D, Dubreuil P, and Hermine O
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Female, Follow-Up Studies, Humans, Kaplan-Meier Estimate, Male, Middle Aged, Retrospective Studies, Treatment Outcome, Young Adult, Antineoplastic Agents therapeutic use, Cladribine therapeutic use, Mastocytosis drug therapy
- Abstract
Mastocytosis (M) is a clonal myeloid-disabling disorder for which no curative therapy is currently available. Cladribine (2-chlorodeoxyadenosine [2-CdA]) is a synthetic purine analog cytoreductive treatment, for which efficacy is mostly reported in advanced M. Here we report, with a long-term follow-up period (>10 years) efficacy and safety in 68 adult patients with M (36 [53%] had indolent M and 32 [47%] had advanced M) treated by 2-CdA (0.14 mg/kg in infusion or subcutaneously, days 1-5; repeated at 4-12 weeks until 1 to 9 courses). Median 2-CdA courses number was 3.7 (1-9). The overall response rate was 72% (complete remission [R]/major/partial R: 0%/47%/25%) and according to indolent/advanced M was 92% (major/partial R: 56%/36%) and 50% (major/partial R: 37.5%/12.5%), respectively. Clinical improvement was observed for 10 of 11 mediator release and 6 of 7 mast cell infiltration-related symptoms including urticaria pigmentosa and organomegaly (P < .02). Serum tryptase levels decreased (P = .01). Median durations of response were 3.71 (0.1-8) and 2.47 (0.5-8.6) years for indolent and aggressive M, respectively. The most frequent grade 3/4 toxicities were lymphopenia (82%), neutropenia (47%), and opportunistic infections (13%). 2-CdA appears to provide a significant efficacy with some toxicity in various M subtypes, mostly in indolent M, refractory to multiple symptomatic therapies., (© 2015 by The American Society of Hematology.)
- Published
- 2015
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30. Tuberculosis in Brazilian prisons: responsibility of the state and double punishment for the inmates.
- Author
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Larouzé B, Ventura M, Sánchez AR, and Diuana V
- Subjects
- Brazil, Human Rights, Humans, Prisoners legislation & jurisprudence, Prisons legislation & jurisprudence, Tuberculosis transmission
- Published
- 2015
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31. Evidence for Flat Bands near the Fermi Level in Epitaxial Rhombohedral Multilayer Graphene.
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Pierucci D, Sediri H, Hajlaoui M, Girard JC, Brumme T, Calandra M, Velez-Fort E, Patriarche G, Silly MG, Ferro G, Soulière V, Marangolo M, Sirotti F, Mauri F, and Ouerghi A
- Abstract
The stacking order of multilayer graphene has a profound influence on its electronic properties. In particular, it has been predicted that a rhombohedral stacking sequence displays a very flat conducting surface state: the longer the sequence, the flatter the band. In such a flat band, the role of electron-electron correlation is enhanced, possibly resulting in high Tc superconductivity, magnetic order, or charge density wave order. Here we demonstrate that rhombohedral multilayers are easily obtained by epitaxial growth on 3C-SiC(111) on a 2° off-axis 6H-SiC(0001). The resulting samples contain rhombohedral sequences of five layers on 70% of the surface. We confirm the presence of the flat band at the Fermi level by scanning tunneling spectroscopy and angle-resolved photoemission spectroscopy, in close agreement with the predictions of density functional theory calculations.
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- 2015
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32. VEGFA SNP rs2010963 is associated with vascular toxicity in recurrent glioblastomas and longer response to bevacizumab.
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Di Stefano AL, Labussiere M, Lombardi G, Eoli M, Bianchessi D, Pasqualetti F, Farina P, Cuzzubbo S, Gallego-Perez-Larraya J, Boisselier B, Ducray F, Cheneau C, Moglia A, Finocchiaro G, Marie Y, Rahimian A, Hoang-Xuan K, Delattre JY, Mokhtari K, and Sanson M
- Subjects
- Bevacizumab, Brain Neoplasms blood, Brain Neoplasms mortality, Disease-Free Survival, Enzyme-Linked Immunosorbent Assay, Genotype, Glioblastoma blood, Glioblastoma mortality, Hemorrhage chemically induced, Hemorrhage epidemiology, Hemorrhage genetics, Humans, Kaplan-Meier Estimate, Neoplasm Recurrence, Local drug therapy, Neoplasm Recurrence, Local genetics, Thrombosis chemically induced, Thrombosis epidemiology, Thrombosis genetics, Vascular Endothelial Growth Factor A blood, Angiogenesis Inhibitors adverse effects, Antibodies, Monoclonal, Humanized adverse effects, Brain Neoplasms drug therapy, Glioblastoma drug therapy, Polymorphism, Single Nucleotide, Vascular Endothelial Growth Factor A genetics
- Abstract
Although anti-VEGF therapy is widely used in high-grade gliomas, no predictor of response or toxicity has been reported yet. We investigated here the association of the functional single nucleotide polymorphism (SNP) rs2010963, located in the 5' untranslated terminal region of the VEGFA gene, with survival, response to bevacizumab (BVZ) and vascular toxicity. The rs2010963 was genotyped by Taqman assay in blood DNA from 954 glioma patients with available survival data, including 225 glioblastoma (GBM) patients treated with BVZ. VEGFA plasma levels were assessed by ELISA in 87 patients before treatment. Thrombo-hemorragic adverse events were recorded during BVZ treatment or not, and in an independent population of 92 GBM patients treated with temozolomide. The CC genotype was associated with the occurrence of thrombo-hemorragic events (CC 25 versus CG 13.5 and GG 5.2 %; P = 0.0044) during BVZ. A similar but weaker and non significant trend was observed in patients not receiving BVZ. A CC genotype was associated with higher levels of plasma VEGFA at baseline (107.6 versus 57.50 pg/mL in heterozygotes (CG) and 52.75 pg/mL in GG patients, P = 0.035 and P = 0.028 respectively). The CC genotype tended to be associated to longer PFS when treated with BVZ (P = 0.05), but not when treated with the temozolomide treatment. Our data suggest that the rs2010963 genotype is associated with longer PFS, higher risk of vascular events in recurrent GBM especially treated with BVZ, and higher plasma VEGFA concentration. It may help to identify patients at risk of vascular adverse events during BVZ treatment.
- Published
- 2015
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33. Prevalence and pathogenicity of binary toxin-positive Clostridium difficile strains that do not produce toxins A and B.
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Eckert C, Emirian A, Le Monnier A, Cathala L, De Montclos H, Goret J, Berger P, Petit A, De Chevigny A, Jean-Pierre H, Nebbad B, Camiade S, Meckenstock R, Lalande V, Marchandin H, and Barbut F
- Abstract
Clostridium difficile causes antibiotic-associated diarrhoea and pseudomembranous colitis. The main virulence factors of C. difficile are the toxins A (TcdA) and B (TcdB). A third toxin, called binary toxin (CDT), can be detected in 17% to 23% of strains, but its role in human disease has not been clearly defined. We report six independent cases of patients with diarrhoea suspected of having C. difficile infection due to strains from toxinotype XI/PCR ribotype 033 or 033-like, an unusual toxinotype/PCR ribotype positive for CDT but negative for TcdA and TcdB. Four patients were considered truly infected by clinicians and were specifically treated with oral metronidazole. One of the cases was identified during a prevalence study of A(-)B(-)CDT(+) strains. In this study, we screened a French collection of 220 nontoxigenic strains and found only one (0.5%) toxinotype XI/PCR ribotype 033 or 033-like strain. The description of such strains raises the question of the role of binary toxin as a virulence factor and could have implications for laboratory diagnostics that currently rarely include testing for binary toxin.
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- 2014
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34. Exome sequencing links corticospinal motor neuron disease to common neurodegenerative disorders.
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Novarino G, Fenstermaker AG, Zaki MS, Hofree M, Silhavy JL, Heiberg AD, Abdellateef M, Rosti B, Scott E, Mansour L, Masri A, Kayserili H, Al-Aama JY, Abdel-Salam GMH, Karminejad A, Kara M, Kara B, Bozorgmehri B, Ben-Omran T, Mojahedi F, El Din Mahmoud IG, Bouslam N, Bouhouche A, Benomar A, Hanein S, Raymond L, Forlani S, Mascaro M, Selim L, Shehata N, Al-Allawi N, Bindu PS, Azam M, Gunel M, Caglayan A, Bilguvar K, Tolun A, Issa MY, Schroth J, Spencer EG, Rosti RO, Akizu N, Vaux KK, Johansen A, Koh AA, Megahed H, Durr A, Brice A, Stevanin G, Gabriel SB, Ideker T, and Gleeson JG
- Subjects
- Animals, Axons physiology, Biological Transport genetics, Cohort Studies, Gene Regulatory Networks, Humans, Mutation, Nucleotides genetics, Nucleotides metabolism, Sequence Analysis, DNA, Synapses physiology, Transcriptome, Zebrafish, Exome genetics, Genetic Association Studies, Motor Neuron Disease genetics, Neurons metabolism, Pyramidal Tracts metabolism, Spastic Paraplegia, Hereditary genetics
- Abstract
Hereditary spastic paraplegias (HSPs) are neurodegenerative motor neuron diseases characterized by progressive age-dependent loss of corticospinal motor tract function. Although the genetic basis is partly understood, only a fraction of cases can receive a genetic diagnosis, and a global view of HSP is lacking. By using whole-exome sequencing in combination with network analysis, we identified 18 previously unknown putative HSP genes and validated nearly all of these genes functionally or genetically. The pathways highlighted by these mutations link HSP to cellular transport, nucleotide metabolism, and synapse and axon development. Network analysis revealed a host of further candidate genes, of which three were mutated in our cohort. Our analysis links HSP to other neurodegenerative disorders and can facilitate gene discovery and mechanistic understanding of disease.
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- 2014
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35. Summer community structure of aerobic anoxygenic phototrophic bacteria in the western Arctic Ocean.
- Author
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Boeuf D, Cottrell MT, Kirchman DL, Lebaron P, and Jeanthon C
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- Alphaproteobacteria classification, Alphaproteobacteria isolation & purification, Bacteria, Aerobic genetics, Bacteria, Aerobic isolation & purification, Betaproteobacteria classification, Betaproteobacteria isolation & purification, Fresh Water microbiology, Oceans and Seas, Photosynthesis genetics, Phylogeny, Bacteria, Aerobic classification, Seasons, Seawater microbiology
- Abstract
Aerobic anoxygenic phototrophic (AAP) bacteria are found in a range of aquatic and terrestrial environments, potentially playing unique roles in biogeochemical cycles. Although known to occur in the Arctic Ocean, their ecology and the factors that govern their community structure and distribution in this extreme environment are poorly understood. Here, we examined summer AAP abundance and diversity in the North East Pacific and the Arctic Ocean with emphasis on the southern Beaufort Sea. AAP bacteria comprised up to 10 and 14% of the prokaryotic community in the bottom nepheloid layer and surface waters of the Mackenzie plume, respectively. However, relative AAP abundances were low in offshore waters. Environmental pufM clone libraries revealed that AAP bacteria in the Alphaproteobacteria and Betaproteobacteria classes dominated in offshore and in river-influenced surface waters, respectively. The most frequent AAP group was a new uncultivated betaproteobacterial clade whose abundance decreased along the salinity gradient of the Mackenzie plume even though its photosynthetic genes were actively expressed in offshore waters. Our data indicate that AAP bacterial assemblages represented a mixture of freshwater and marine taxa mostly restricted to the Arctic Ocean and highlight the substantial influence of riverine inputs on their distribution in coastal environments., (© 2013 Federation of European Microbiological Societies. Published by John Wiley & Sons Ltd. All rights reserved.)
- Published
- 2013
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36. THE LESSONIA NIGRESCENS SPECIES COMPLEX (LAMINARIALES, PHAEOPHYCEAE) SHOWS STRICT PARAPATRY AND COMPLETE REPRODUCTIVE ISOLATION IN A SECONDARY CONTACT ZONE(1).
- Author
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Tellier F, Tapia J, Faugeron S, Destombe C, and Valero M
- Abstract
During secondary contact between phylogenetically closely related species (sibling species) having diverged in allopatry, the maintenance of species integrity depends on intrinsic and extrinsic reproductive barriers. In kelps (Phaeophyceae), the observations of hybrids in laboratory conditions suggest that reproductive isolation is incomplete. However, not all interspecific crosses are successful, and very few hybrids have been observed in nature, despite the co-occurrence of many kelp species in sympatry. This suggests that there are reproductive barriers that maintain species integrity. In this study, we characterized the fine genetic structure of a secondary contact zone to clarify the extent of reproductive isolation between two sister species. In Lessonia nigrescens Bory (Laminariales, Phaeophyta) species complex, two cryptic species have been recently found out from gene phylogenies, and-waiting for a formal taxonomic description-we used their geographic distribution to name them (northern and southern species). We studied 12 populations, distributed along 50 km of coastline, and employed two molecular approaches, assigning individuals to phylogenetic species according to a diagnostic mitochondrial marker (351 individuals analyzed) and quantifying interspecific gene flow with four microsatellite markers (248 individuals analyzed). No hybridization or introgression was revealed, indicating complete reproductive isolation in natural conditions. Unexpectedly, our study demonstrated that the two species were strictly segregated in space. This absence of co-occurrence along the contact zone can partially explain the lack of hybridization, raising new interesting questions as to the mechanisms that limit sympatry at small spatial scales., (© 2011 Phycological Society of America.)
- Published
- 2011
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37. Biogenesis of PSI involves a cascade of translational autoregulation in the chloroplast of Chlamydomonas.
- Author
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Wostrikoff K, Girard-Bascou J, Wollman FA, and Choquet Y
- Subjects
- 5' Untranslated Regions, Animals, Chlamydomonas reinhardtii genetics, Down-Regulation, Gene Expression Regulation, Plant, Genes, Plant, Genes, Reporter, Models, Biological, Photosystem I Protein Complex genetics, Photosystem I Protein Complex isolation & purification, Plant Proteins metabolism, Transformation, Genetic, Chlamydomonas reinhardtii physiology, Chloroplasts metabolism, Organelle Biogenesis, Photosystem I Protein Complex physiology, Protein Biosynthesis, RNA Processing, Post-Transcriptional
- Abstract
Photosystem I comprises 13 subunits in Chlamydomonas reinhardtii, four of which-the major reaction center I subunits PsaA and PsaB, PsaC and PsaJ-are chloroplast genome-encoded. We demonstrate that PSI biogenesis involves an assembly-governed regulation of synthesis of the major chloroplast-encoded subunits where the presence of PsaB is required to observe significant rates of PsaA synthesis and the presence of PsaA is required to observe significant rates of PsaC synthesis. Using chimeric genes expressed in the chloroplast, we show that these regulatory processes correspond to autoregulation of translation for PsaA and PsaC. The downregulation of translation occurs at some early stage since it arises from the interaction between unassembled PsaA and PsaC polypeptides and 5' untranslated regions of psaA and psaC mRNAs, respectively. These assembly-dependent autoregulations of translation represent two new instances of a control by epistasy of synthesis process that turns out to be a general feature of protein expression in the chloroplast of C. reinhardtii.
- Published
- 2004
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38. Nociceptive reflexes and pain sensation in man.
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Willer JC, Dehen H, Boureau F, Cambier J, and Albe-Fessard D
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- Electric Stimulation, Humans, Muscles innervation, Reflex, Sensory Thresholds, Skin innervation, Nociceptors physiology, Pain physiopathology
- Published
- 1981
- Full Text
- View/download PDF
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