887 results on '"Unanue, Emil R."'
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2. Crinophagic granules in pancreatic β cells contribute to mouse autoimmune diabetes by diversifying pathogenic epitope repertoire
3. Role of the afferent lymph as an immunological conduit to analyze tissue antigenic and inflammatory load
4. Pancreatic islets communicate with lymphoid tissues via exocytosis of insulin peptides
5. Cytocidal macrophages in symbiosis with CD4 and CD8 T cells cause acute diabetes following checkpoint blockade of PD-1 in NOD mice
6. TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy
7. The MHC-II peptidome of pancreatic islets identifies key features of autoimmune peptides
8. MHC-II neoantigens shape tumour immunity and response to immunotherapy
9. Direct Recognition by αβ Cytolytic T Cells of Hfe, a MHC Class Ib Molecule without Antigen-Presenting Function
10. The Evolution of Vertebrate Toll-Like Receptors
11. The Primary Mechanism of the IL-10-Regulated Antiinflammatory Response Is to Selectively Inhibit Transcription
12. Activated Antigen-Presenting Cells Select and Present Chemically Modified Peptides Recognized by Unique CD4 T Cells
13. A Hairpin Turn in a Class II MHC-Bound Peptide Orients Residues outside the Binding Groove for T Cell Recognition
14. Essential Role of CD91 in Re-Presentation of gp96-Chaperoned Peptides
15. Resident macrophages of pancreatic islets have a seminal role in the initiation of autoimmune diabetes of NOD mice
16. Specificity of Peptide Selection by Antigen-Presenting Cells Homozygous or Heterozygous for Expression of Class II MHC Molecules: The Lack of Competition
17. TREM2 Maintains Microglial Metabolic Fitness in Alzheimer’s Disease
18. Unique features in the presentation of insulin epitopes in autoimmune diabetes: an update
19. Despite Ubiquitous Autoantigen Expression, Arthritogenic Autoantibody Response Initiates in the Local Lymph Node
20. Distinct Recognition by Two Subsets of T Cells of an MHC Class II-Peptide Complex
21. Hindering Auxiliary Anchors Are Potent Modulators of Peptide Binding and Selection by I-A k Class II Molecules
22. The Lack of Consensus for I-Ag7-Peptide Binding Motifs: Is There a Requirement for Anchor Amino Acid Side Chains?
23. Autoreactivity of T Cells from Nonobese Diabetic Mice: An I-A g7 -dependent Reaction
24. The resident macrophages in murine pancreatic islets are constantly probing their local environment, capturing beta cell granules and blood particles
25. Antigen Receptor Engagement Delivers a Stop Signal to Migrating T Lymphocytes
26. Amino-Terminal Trimming of Peptides for Presentation on Major Histocompatibility Complex Class II Molecules
27. Macrophages and dendritic cells in islets of Langerhans in diabetic autoimmunity: a lesson on cell interactions in a mini-organ
28. Antigen presentation events during the initiation of autoimmune diabetes in the NOD mouse
29. Beta cells transfer vesicles containing insulin to phagocytes for presentation to T cells
30. Immunological Reversal of Autoimmune Diabetes without Hematopoietic Replacement of β Cells
31. CD2-Associated Protein Haploinsufficiency Is Linked to Glomerular Disease Susceptibility
32. A Minor Subset of Batf3-Dependent Antigen-Presenting Cells in Islets of Langerhans Is Essential for the Development of Autoimmune Diabetes
33. The central role of antigen presentation in islets of Langerhans in autoimmune diabetes
34. Embryonic and Adult-Derived Resident Cardiac Macrophages Are Maintained through Distinct Mechanisms at Steady State and during Inflammation
35. A novel pathway of presentation by class II-MHC molecules involving peptides or denatured proteins important in autoimmunity
36. Perspectives on anti-CD47 antibody treatment for experimental cancer
37. Macrophages in Endocrine Glands, with Emphasis on Pancreatic Islets
38. Antigen presentation events in autoimmune diabetes
39. Alloreactivity is limited by the endogenous peptide repertoire
40. Cellular and molecular events in the localization of diabetogenic T cells to islets of Langerhans
41. Entry of diabetogenic T cells into islets induces changes that lead to amplification of the cellular response
42. Evolving concepts of specificity in immune reactions
43. Bidirectional binding of invariant chain peptides to an MHC class II molecule
44. Expansion of human NK-22 cells with IL-7, IL-2, and IL-1β reveals intrinsic functional plasticity
45. NADPH oxidase activity controls phagosomal proteolysis in macrophages through modulation of the lumenal redox environment of phagosomes
46. Peptide antagonism as a mechanism for NK cell activation
47. Targeting Proteins to Distinct Subcellular Compartments Reveals Unique Requirements for MHC Class I and II Presentation
48. Identification of Tumor-Associated, MHC Class II-Restricted Phosphopeptides as Targets for Immunotherapy
49. Cellular Immune Response to Cryptic Epitopes during Therapeutic Gene Transfer
50. Activation of Antibacterial Autophagy by NADPH Oxidases
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