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1. IDENTIFICATION OF Tapr (AN AIRWAY HYPERREACTIVITY REGULATORY LOCUS) AND THE LINKED Tim GENE FAMILY.

Author

McIntire, J.J., Umetsu, S.E., Akbari, O., Thatayatikom, Akaluck, and Liu, Andrew H.

Subjects
*ASTHMA, *GENETICS, *ALLERGIES, *CLONING
Abstract

Presents information on a study featured in the 2001 issue of "Nature Immunology," which identified a central asthma susceptibility gene in the large chromosome 5q23-35 region that has been linked to asthma and atopy, using mouse models of asthma. Congenic inbred mouse strains; Information taken from the positional cloning approach; Identification of a novel gene cluster of Tim genes in mouse and man.

Published
2003

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