114 results on '"Uluğ, Mehmet"'
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2. Examining the impact of clean environmental regulations on load capacity factor to achieve sustainability: Evidence from APEC economies
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Caglar, Abdullah Emre, Pata, Ugur Korkut, Ulug, Mehmet, and Zafar, Muhammad Wasif
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- 2023
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3. A snapshot of geriatric infections in Turkey: ratio of geriatric inpatients in hospitals and evaluation of their infectious diseases: A multicenter point prevalence study
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Aslaner, Hande, Ulu, Aslıhan, Sehmen, Emine, Erol, Serpil, Kızmaz, Yeşim Uygun, Durmuş, Gül, Işık, M Emirhan, Solay, Aslı Haykır, Komur, Suheyla, Azak, Emel, Yavuz, İlknur, Karagöz, Ergenekon, Sayar, Merve Sefa, Naz, Hasan, Demirbaş, Zehra, İnce, Nevin, Korkmaz, Fatime, Armağan, Şule Özdemir, Savaşçı, Ümit, Aktaş, Sabahat, Tigen, Elif Tükenmez, Şengel, Buket Ertürk, Gürsul, Nur Cancan, Acar, Ali, Sarı, Sema, Turan, Sema, Kostakoğlu, Uğur, Evik, Güliz, Arslan, Kader, Kılıç, Esra Kaya, Atilla, Aynur, Ağalar, Canan, Ateş, Selma, Uğurlu, Kenan, Doğan, Mustafa, Bilman, Funda, Kılıçaslan, Nirgül, Okay, Gülay, Altunal, Nilsun, Balkan, Yasemin, Yetik, Mevliye, Uysal, Serhat, Baran, A İrfan, Erben, Nurettin, Aydemir, Hande, Sezer, B Ergüt, Daldal, Abdulkadir, Kadanalı, Ayten, Tartar, Ayşe Sağmak, Şener, Alper, Harman, Rezan, Ceylan, M Reşat, Ürgüdücü, Hatice, Dökmetaş, İlyas, Hamidi, Ahmet, Yıldırım, A Altunçekiç, Kaygusuz, Sedat, Yılmaz, Esmeray Mutlu, Esen, Şaban, Nazik, Selçuk, Koç, Filiz, Özden, Hale Turan, Demirel, Aslıhan, Kürekçi, Yeşim, Erdoğan, Haluk, Göktaş, Emine Fırat, Uluğ, Mehmet, Kuşoğlu, Hülya, Gözüküçük, Ramazan, Elmaslar Mert, Habibe Tülin, Erdem, İlknur, Şahintürk, Hüseyin, Aliravcı, Işıl Deniz, Ali, Rıdvan Kara, Koçak, Funda, Yıldız, İE, Aslan, Emel, Karadağ, Fatma Yılmaz, Inal, A Seza, Tasova, Yesim, Kurtaran, Behice, Kuscu, Ferit, Korkmaz, Pinar, Ozdemir, Burcu, Inan, Dilara, Oztoprak, Nefise, Ozatag, Duru Mistanoglu, Daglı, Ozgur, Birengel, Serhat, and Ozdemir, Kevser
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- 2020
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4. Comparison of brucellar and tuberculous spondylodiscitis patients: results of the multicenter “Backbone-1 Study”
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Erdem, Hakan, Elaldi, Nazif, Batirel, Ayse, Aliyu, Sani, Sengoz, Gonul, Pehlivanoglu, Filiz, Ramosaco, Ergys, Gulsun, Serda, Tekin, Recep, Mete, Birgul, Balkan, Ilker Inanc, Sevgi, Dilek Yildiz, Giannitsioti, Efthymia, Fragou, Archontoula, Kaya, Selcuk, Cetin, Birsen, Oktenoglu, Tunc, DoganCelik, Aygul, Karaca, Banu, Horasan, Elif Sahin, Ulug, Mehmet, Inan, Asuman, Kaya, Safak, Arslanalp, Esra, Ates-Guler, Selma, Willke, Ayse, Senol, Sebnem, Inan, Dilara, Guclu, Ertugrul, Tuncer-Ertem, Gunay, Meric-Koc, Meliha, Tasbakan, Meltem, Senbayrak, Seniha, Cicek-Senturk, Gonul, Sırmatel, Fatma, Ocal, Gulfem, Kocagoz, Sesin, Kusoglu, Hulya, Guven, Tumer, Baran, Ali Irfan, Dede, Behiye, Yilmaz-Karadag, Fatma, Kose, Sukran, Yilmaz, Hava, Aslan, Gonul, ALGallad, D. Ashraf, Cesur, Salih, El-Sokkary, Rehab, Bekiroğlu, Nural, and Vahaboglu, Haluk
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- 2015
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5. Tuberculous and brucellosis meningitis differential diagnosis
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Erdem, Hakan, Senbayrak, Seniha, Gencer, Serap, Hasbun, Rodrigo, Karahocagil, Mustafa Kasim, Sengoz, Gonul, Karsen, Hasan, Kaya, Selçuk, Civljak, Rok, Inal, Ayşe Seza, Pekok, Abdullah Umut, Celen, Mustafa Kemal, Deniz, Secil, Ulug, Mehmet, Demirdal, Tuna, Namiduru, Mustafa, Tekin, Recep, Guven, Tumer, Parlak, Emine, Bolukcu, Sibel, Avci, Meltem, Sipahi, Oğuz Reşat, Nayman-Alpat, Saygin, Yaşar, Kadriye, Pehlivanoğlu, Filiz, Yilmaz, Emel, Ates-Guler, Selma, Mutlu-Yilmaz, Esmeray, Tosun, Selma, Sirmatel, Fatma, Şahin-Horasan, Elif, Akbulut, Ayhan, Johansen, Işik Somuncu, Simeon, Soline, Batirel, Ayşe, Öztoprak, Nefise, Cag, Yasemin, Catroux, Melanie, Hansmann, Yves, Kadanali, Ayten, Turgut, Huseyin, Baran, Ali Irfan, Gul, Hanefi Cem, Karaahmetoglu, Gokhan, Sunnetcioglu, Mahmut, Haykir-Solay, Asli, Denk, Affan, Ayaz, Celal, Kose, Sukran, and Gorenek, Levent
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- 2015
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6. Stevens-Johnson syndrome caused by combined use of lamotrigine and fluoxetine and review of the literature
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Uluğ Mehmet, Uluğ Nuray, Celen Mustafa, Geyik Mehmet, and Ayaz Celal
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stevens — johnson syndrome ,lamotrigine ,fluoxetine ,medical treatment ,Medicine - Published
- 2010
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7. The evaluation of bacteriology in perianal abscesses of 81 adult patients
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Ulug, Mehmet, Gedik, Ercan, Girgin, Sadullah, Kemal Celen, Mustafa, and Ayaz, Celal
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- 2010
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8. The evaluation of microbiology and Fournier's gangrene severity index in 27 patients
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Uluğ, Mehmet, Gedik, Ercan, Girgin, Sadullah, Çelen, Mustafa K., and Ayaz, Celal
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- 2009
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9. A snapshot of geriatric infections in Turkey: ratio of geriatric inpatients in hospitals and evaluation of their infectious diseases: A multicenter point prevalence study
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Kurtaran, Behice, primary, Kuscu, Ferit, additional, Korkmaz, Pinar, additional, Ozdemir, Burcu, additional, Inan, Dilara, additional, Oztoprak, Nefise, additional, Ozatag, Duru Mistanoglu, additional, Daglı, Ozgur, additional, Birengel, Serhat, additional, Ozdemir, Kevser, additional, Aslaner, Hande, additional, Ulu, Aslıhan, additional, Sehmen, Emine, additional, Erol, Serpil, additional, Kızmaz, Yeşim Uygun, additional, Durmuş, Gül, additional, Işık, M Emirhan, additional, Solay, Aslı Haykır, additional, Komur, Suheyla, additional, Azak, Emel, additional, Yavuz, İlknur, additional, Karagöz, Ergenekon, additional, Sayar, Merve Sefa, additional, Naz, Hasan, additional, Demirbaş, Zehra, additional, İnce, Nevin, additional, Korkmaz, Fatime, additional, Armağan, Şule Özdemir, additional, Savaşçı, Ümit, additional, Aktaş, Sabahat, additional, Tigen, Elif Tükenmez, additional, Şengel, Buket Ertürk, additional, Gürsul, Nur Cancan, additional, Acar, Ali, additional, Sarı, Sema, additional, Turan, Sema, additional, Kostakoğlu, Uğur, additional, Evik, Güliz, additional, Arslan, Kader, additional, Kılıç, Esra Kaya, additional, Atilla, Aynur, additional, Ağalar, Canan, additional, Ateş, Selma, additional, Uğurlu, Kenan, additional, Doğan, Mustafa, additional, Bilman, Funda, additional, Kılıçaslan, Nirgül, additional, Okay, Gülay, additional, Altunal, Nilsun, additional, Balkan, Yasemin, additional, Yetik, Mevliye, additional, Uysal, Serhat, additional, Baran, A İrfan, additional, Erben, Nurettin, additional, Aydemir, Hande, additional, Sezer, B Ergüt, additional, Daldal, Abdulkadir, additional, Kadanalı, Ayten, additional, Tartar, Ayşe Sağmak, additional, Şener, Alper, additional, Harman, Rezan, additional, Ceylan, M Reşat, additional, Ürgüdücü, Hatice, additional, Dökmetaş, İlyas, additional, Hamidi, Ahmet, additional, Yıldırım, A Altunçekiç, additional, Kaygusuz, Sedat, additional, Yılmaz, Esmeray Mutlu, additional, Esen, Şaban, additional, Nazik, Selçuk, additional, Koç, Filiz, additional, Özden, Hale Turan, additional, Demirel, Aslıhan, additional, Kürekçi, Yeşim, additional, Erdoğan, Haluk, additional, Göktaş, Emine Fırat, additional, Uluğ, Mehmet, additional, Kuşoğlu, Hülya, additional, Gözüküçük, Ramazan, additional, Elmaslar Mert, Habibe Tülin, additional, Erdem, İlknur, additional, Şahintürk, Hüseyin, additional, Aliravcı, Işıl Deniz, additional, Ali, Rıdvan Kara, additional, Koçak, Funda, additional, Yıldız, İE, additional, Aslan, Emel, additional, Karadağ, Fatma Yılmaz, additional, Inal, A Seza, additional, and Tasova, Yesim, additional
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- 2020
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10. Daptomycin versus glycopeptides in the treatment of osteomyelitis: results of a multi-centre retrospective cohort study
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ERDEM, HÜSEYİN AYTAÇ, KURŞUN, EBRU, suntur, mutay, DEMİRDAL, TUNA, Sipahi, Hilal, NEMLİ, SALİH ATAKAN, DİZBAY, MURAT, ULUSOY, SERCAN, uluğ, mehmet, ARDA, BİLGİN, güliyeva, günel, TAŞBAKAN, MELTEM, uysal, serhat, SİPAHİ, OĞUZ REŞAT, and kahraman, hasip
- Published
- 2018
11. AVRUPA BİRLİĞİ ÜYESİ 13 ÜLKEDE POST-KEYNESYEN PARA ARZININ İÇSELLİĞİ HİPOTEZİNİN TEST EDİLMESİ
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IŞIK, Sayım, ALKIN, Huriye, and ULUĞ, Mehmet
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Post Keynesyenler,Para Arzı,İçsellik - Abstract
Bu çalışmanın amacı Post Keynesyen paranıniçselliği teorisinin 2001-2015 yıllarını kapsayan dönemde 13 Avrupa Birliğiülkesi için analiz edilmesidir. Bu amaç çerçevesinde birim kök testi,eşbütünleşme testleri, Panel ARDL ve ardından Granger nedensellik testleriyapılmıştır. Sonuç olarak çalışmanın genel sonuçları,13 Avrupa Birliği ülkesi için Post-Keynesyen paranın içselliği yaklaşımınıdesteklemektedir. Bu bağlamda ampirik bulgular, bu ülkelerde halkın paratalebini karşılamak için bankalar tarafından yaratılan kredilerin para arzıiçin temel teşkil ettiğini göstermektedir.
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- 2018
12. TESTING OF POST-KEYNESIAN ENDOGENEITY OF MONEY SUPPLY HYPOTHESIS FOR THE 13 MEMBER STATES OF EUROPEAN UNION
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IŞIK, Sayım, primary, ALKIN, Huriye, primary, and ULUĞ, Mehmet, primary
- Published
- 2018
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13. Monetary trsanmission mechanism and determinants of lending channel in the Turkish banking sector: Panel data analysis
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Uluğ, Mehmet, Ekonometri, Mehmet Mert, Sosyal Bilimler Enstitüsü, Mert, Mehmet, and Ekonometri Ana Bilim Dalı
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Economics ,Parasal Aktarım Mekanizması, Banka Kredi Kanalı, Panel Veri Açıklayıcı DeğiĢkenler, Türk Bankacılık Sektörü ,Panel data models ,Bankacılık ,Credits ,Banking ,Bank leading channel ,Banks ,Turkish banking sector ,Ekonometri ,Monetary transmission ,Econometrics ,Bank credits ,Ekonomi ,Banking sector - Abstract
Parasal aktarım mekanizmasında banka kredi kanalının belirleyicilerinin tespit edilmesi ve bu kanalın varlığı hakkında bilgiler ülke deneyimlerine göre şüpheler bulunmaktadır. Buna göre, Türkiye'de banka kredi kanalının belirleyicilerini tespiti amacıyla ampirik bir araştırmaya başvurulacaktır. Böylece, bu tezin ana amaçları olarak bankaların rolü, banka kredi kanalının belirleyicileri ve Türkiye'de parasal aktarım mekanizmasında banka kredi kanalının varlığını analiz etmektir. Banka kredi kanalının belirleyicilerini açıklamak için regresyon analizimiz, Bernanke ve Blinder modelinin (1988) bir versiyonu olan diğer banka içi değişkenlerin ilave edildiği genişletilmiş modeline dayanmaktadır. Bu amaçlara ulaşmak için Türkiye'de faaliyet gösteren 24 özel ve yabancı sermayeli bankanın yıllık verileri 2003-2013 yıllarını kapsayan bir dönemde analiz edilmektedir. Tam model sermaye yeterliliği, aktif kalitesi, likidite, mevduat ve karlılık gibi bankacılığa özgü değişkenlerle birlikte; para politikası göstergesi ve bir makro ekonomik değişken grubunun önemi göz önünde bulundurularak elde edilmiştir. Panel veri analiz sonuçlarına göre, Türkiye'de parasal aktarım mekanizmasında bankaların önemli bir oynadıkları, bankacılığa özgü değişkenlerin yanında kontrol değişkenler olarak modele dâhil edilen makro ekonomik faktörlerin de Türkiye'de banka kredi kanalı için önemli belirleyiciler olduğunu göstermiştir. Bulgular sermaye yeterliliği ve likiditenin banka kredileri ile negatif ilişkili iken bankanın aktif yapısı ve karlılığın banka kredileri ile pozitif ilişkili olduğunu göstermektedir. Bunun yanında para politikası göstergesinin banka kredileri üzerine negatif etkilere sahip olduğu tespit edilmiştir. Makro ekonomik değişkenlerden milli gelir ve enflasyon, banka kredilerini pozitif etkilemektedir. Ana sonuç olarak, bulgularımız Türkiye ekonomisinde bir banka kredi kanalının varlığını destekleyen bulgular sunmaktadır.Anahtar Kelimeler: Parasal Aktarım Mekanizması, Banka Kredi Kanalı, Panel Veri Açıklayıcı DeğiĢkenler, Türk Bankacılık Sektörü There are some doubts about the determinants of bank lending channel transmission of monetary policy in some countries and in some cases about its own existence. Accordingly, we will carry out an empirical research to appreciate these issues. Thus, the main objectives of this thesis to analyze the banks role, the determinants of the bank lending channel and the existence of this channel of monetary transmission mechanism in Turkey. In order to explain the determinants of bank lending channel, our regression analysis is based on a version of a Bernanke and Blinder (1988) model, which was modified by other bank specific variables thus extending the approach of the above mentioned model. In order to reach these objects we analyze a sample with annual data of 24 Turkish private and foreign banks covering a period of 2003-2013. The full model is obtained not only through the bank specific variables, such as, capital adequacy, asset structure, liquidity, deposits and profitability, but also by considering the importance of the monetary policy indicator and a set of macroeconomic variables.According to panel data results, banks play an important role in the Turkish monetary transmission mechanism, and that bank specific characteristics, as well as macroeconomic factors, which are introduced into the model as control variables, are important determinants of the credit channel in Turkey. Findings of this study indicate that asset structure and profitability have a statistically significant and positive relationship, whereas capital adequacy and liquidity have a negative relationship with the bank lending behavior. Besides this the monetary policy indicator is found to have a negative effect on bank loans. Regarding the macroeconomic variables, gross domestic product and inflation have positive and significant effects for the bank loans. As a main conclusion, our findings provide evidence to support that a bank lending channel in the Turkish economy does exist.Keywords: Monetary Transmission Mechanism, Bank Lending Channel, Panel Data, Explicative Factor, Turkish Banking Sector. 63
- Published
- 2016
14. Herpetik Santral Sinir Sistemi Enfeksiyonlarının Yönetimi
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BASTAKOVA, L, KÖMÜR, SÜHEYLA, KORKMAZ, F, Pehlivanoğlu, Filiz, PARLAK, EMİNE, KANJ, S, YAKAN, AH, YILMAZ, H, YILMAZ, GULDEN, SUNBUL, M, ŞENGÖZ, NEFİSE GÖNÜL, KARSEN, H, MARESCA, M, FONTANA, R, SHEHATA, G, BERAUD, G, CHEHRI, M, SİPAHİ, OĞUZ REŞAT, PEKOK, ABDULLAH UMUT, KARABAY, OĞUZ, SOMUNCU JOHANSEN, ISIK, JEREB, M, GUNST, JD, TATTEVIN, P, BOHR, L, MAJ SORENSEN, S, ARGEMI, X, BARSIC, B, ÖZTÜRK ENGİN, DERYA, POLJAK, M, LARSEN, L, KAYA, SELÇUK, DEFRES, S, LEİB, S, ÇAĞ, YASEMİN, ERDEM, HAKAN, KÖSE, ŞÜKRAN, VAHABOĞLU, MUSTAFA HALUK, ELALDI, NAZİF, ŞENBAYRAK, SENİHA, İnan, Asuman, NEMLİ, SALİH ATAKAN, MAHDAWİ, AA, KILIÇOĞLU, ZEYNEP GAMZE, TİRELİ, HÜLYA, ŞAHİN HORASANLI, ELİF, HALAÇ, GÜLİSTAN, AKKOYUNLU, YASEMİN, İNCE, NEVİN, STAHL, JP, COSKUNER, SA, BOLUKÇU, SİBEL, and ULUĞ, MEHMET
- Published
- 2015
15. Kronik osteomiyelitli olgularda kemik doku ve burun sürüntü kültürlerinden izole edilen stafilokok türlerinin değerlendirilmesi
- Author
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ULUĞ, Mehmet, AYAZ, Celal, and ÇELEN, Mustafa Kemal
- Subjects
Chronic osteomyelitis,nasal carriage,Staphylococcus aureus,bone culture ,Konik osteomiyelit,nazal taşıyıcılık,Staphylococcus aureus,kemik kültürü - Abstract
Objective: In this study, it was aimed to determine the prevalence of nasal carriage of S. aureus in chronic osteomyelitis, assessed trends in methicillin resistance with time, and evaluated the bone and nasal cultures in staphylococcal chronic osteomyelitis. Materials and methods: Bone and nasal cultures were performed intra-operative and pre-operatively from 43 patients with chronic osteomyelitis. Inoculation was performed on 5% sheep blood and eosine-methylen-blue agar. The samples were incubated at 37°C for 24 hours. Catalase and coagulase tests were performed on Gram positive coccus strains. Antimicrobial susceptibilities of all S. aureus strains were evaluated by disc diffusion method according to CLSI for oxacillin and other antibiotics. Results: In this study pre-operative nasal cultures and intra-operative bone cultures obtained between May 2005 and September 2006 were evaluated retrospectively. Of the 43 nasal cultures, 31 (72%) yielded staphylococcal strain, of these 18 (58%) were S. aureus. Of the 18 S. aureus strains, 13 (72.2%) have methicilline resistance. On the other hand, of the 43 bone cultures, 29 (67.4%) yielded staphylococci strain, of these 23 (79.3%) were S. aureus. Of the 23 S. aureus strains, 52.1% have methicilline resistance. Overall the similarity rate of staphylococcal strains was 38% (11/29), while considering the status of strains resistant to antibiotics; this ratio was 24% (7/29). Conclusion: Nasal S. aureus carriage rate (58%) in patients with chronic osteomyelitis was higher than the community and the other patient groups. However, the surveillance cultures can give knowledge about the causative pathogen of 25% of the culture negative cases., Amaç: Bu çalışmada, kronik osteomiyelitli olgularda nazal S. aureus taşıyıcılığının sıklığı ile bu türlerde metisilin direncinin araştırılması ve stafilokokkal kronik osteomiyelitli olgularda kemik doku ve burun sürüntü kültürü sonuçlarının değerlendirilmesi amaçlanmıştır. Gereç ve yöntem: Kronik osteomiyelitli 43 olgunun kemik kültürleri operasyon esnasında, burun sürüntü kültürleri ise operasyon öncesinde alındı. Örnekler %5 koyun kanlı ve eosin metilen blue agar plaklarına ekimi yapılarak, 37oC’de 24 saat inkübe edildi. Gram pozitif kok morfolojisi gösteren kolonilere katalaz ve koagülaz testleri uygulandı. Tüm S. aureus izolatlarının oksasilin ve diğer bazı antibiyotiklere duyarlılıkları CLSI önerilerine göre disk difüzyon yöntemi ile araştırıldı. Bulgular: Bu çalışmada, Mayıs 2005 ile Eylül 2006 tarihleri arasındaki döneme ait operasyon öncesi alınan burun kültürleri ile operasyon esnasında alınan kemik doku kültürleri retrospektif olarak değerlendirilmiştir. Burun kültürlerinin %72’sinde (31/43) stafilokok türleri tespit edilirken, bu türlerden %58’i (18/31) S.aureus tanımlanmış ve %72,2’sinde (13/18) metisiline direnç görülmüştür. Kemik doku kültüründen ise 29 hastada (%67,4) stafilokok türleri izole edilmiş, bu türlerin %79,3’ü (23/29) S. aureus olarak tanımlanmış ve %52,1’inde metisiline direnç saptanmıştır. İzole edilen stafilokok türlerinde benzerlik oranı 11/29 (%38) iken türlerin çalışılan antibiyotiklere direnç durumları göz önüne alındığında bu oran 7/29 (%24) bulunmuştur. Sonuç: Kronik osteomiyelitli hastalarda nazal S. aureus taşıyıcılığı oranı (%58) topluma ve diğer hasta gruplarına göre daha yüksek bulundu. Bununla birlikte, bu hastalarda sürveyans kültürleri, etken patojenin tespit edilemediği olguların %25’inde, etken hakkında fikir verebilir.
- Published
- 2015
16. Fetal seyirli fournier gangreni: Bir olgu sunumu
- Author
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Çelen, Mustafa Kemal, Uluğ, Mehmet, Tekin, Recep, Geyik, Mehmet Faruk, Ayaz, Celal, Dicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Ana Bilim Dalı, Çelen, Mustafa Kemal, Uluğ, Mehmet, Tekin, Recep, Geyik, Mehmet Faruk, and Ayaz, Celal
- Subjects
Fournier gangreni ,Komplikasyon ,Tedavi ,Therapy ,Complication - Abstract
Fournier gangreni, genital bölgenin ve perinenin aerobik ve anaerobik bakterilere ba¤l› olarak geliflen ve nadir görülen nekrotizan fasiitidir. Bu sinerjistik infeksiyon multipl organ disfonksiyonu ve ölüm gibi ciddi komplikasyonlara yol açmaktad›r. Bu hastal›¤›n do¤al olarak agressif tedavisi için öncelikli olan tan›n›n erken konmas›d›r. Tedavideki as›l nokta, genifl doku debritman› ile birlikte genifl spektrumlu antibiyoterapinin uygulanmas›d›r. Tedaviye ra¤men mortalite yüksek seyretmektedir. Bu olguda ürosepsis ve genital bölgede mevcut nekrotik lezyonla acile baflvuran yafll› bir erkek hasta irdelenmifltir. Fournier’s gangrene is a rare, necrotising fasciitis of the genitals and perineum caused by a mixture of aerobic and anaerobic microorganisms. The complications of this synergistic infection are multiple organ failure and death. Due to the aggressive nature of this condition, early diagnosis is crucial. Treatment involves extensive soft tissue debridement and broadspectrum antibiotics. Despite appropriate therapy, mortality is high. Here we report a case of an elderly man who applied to Accident and Emergency Unit with ureosepsis and necrotic perineal areas.
- Published
- 2008
17. Comparision of the results of sinus track culture and bone culture in chronic osteomyelitis
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Uluğ, Mehmet, Ayaz, Celal, Klinik Mikrobiyoloji ve Enfeksiyon Hastalıkları Anabilim Dalı, Dicle Üniversitesi, Tıp Fakültesi, Klinik Mikrobiyoloji ve İnfeksiyon Hastalıkları Anabilim Dalı, and Uluğ, Mehmet
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Mikrobiyoloji ,Kronik osteomiyelit ,Clinical Microbiology and Infectious Diseases ,Klinik Bakteriyoloji ve Enfeksiyon Hastalıkları ,Ortopedi ve Travmatoloji ,Orthopedics and Traumatology ,Patogenez - Abstract
ÖZETKRON K OSTEOM YEL TL HASTALARDA F STÜL AĞZI AKINTI KÜLTÜRÜLE KEM K DOKU KÜLTÜRÜ SONUÇLARININ KARŞILAŞTIRILMASIMehmet UluğDÜTF Klinik Mikrobiyoloji ve nfeksiyon HastalıklarıGiriş: Osteomiyelit, farklı mikroorganizmalara bağlı olarak gelişen, kemik ve kemikiliğinin inflamatuvar bir hastalığı olarak tanımlanır. Bu çalışmada, kronik osteomiyelitlihastalardan alınan fistül ağzı ve kemik doku örneklerinde üreyen etkenler karşılaştırılmış oluposteomiyelitin mikrobiyolojik tanısında bu örneklerin ne dereceye kadar yardımcı olduğusaptanmaya çalışılmıştır.Materyal ve Metod: Bu çalışmaya Mayıs 2005 ile Eylül 2006 tarihleri arasında DicleÜniversitesi Tıp Fakültesi Hastanesi'nde yatan, klinik olarak kronik osteomiyelit ile uyumlu43 hasta alındı.Bulgular: Hastaların 29'u (%67) erkek, 14'ü (%33) kadındı. Hastaların yaş ortalaması±SD30,6 ± 3,6 yıl, ESH ortalaması±SD 82,7 mm/saat ± 4,4, CRP değeri ortalaması±SD 122,4mg/dl ± 11, lökosit sayı ortalaması±SD 11099,3/mm3 ± 640 olarak bulundu. ESH ve CRPyüksekliği istatistiksel olarak da anlamlı bulunurken, lökosit sayısı anlamlı bulunmadı. Kemikdoku kültüründe en sık izole edilen mikroorganizmalar, stafilokoklar %72,5 (29/40),Escherichia coli %10 (4/40), P. aeruginosa %10 (4/40), Proteus mirabilis %7,5 (3/40) idi.Tüm hastalar içerisinde her iki kültürde aynı mikroorganizmanın izole edilme oranı %62,7 idi.Bu oran stafilokok osteomiyelitlerinde ise %78 olarak saptandı.Sonuç: Çalışma sonucunda fistül ağzı akıntı örnekleri ile kemik doku örneklerinden izoleedilen infeksiyon etkenleri arasında %37,3 gibi büyük bir uyumsuzluk olduğu görülmüştür.Bu da yaklaşok olarak her 10 hastadan dördünde tedavide başarısızlık anlamına gelmektedir.KOM'da antibiyoterapi başlamadan önce, alınacak kemik doku kültürünün sonucunubeklemek, hem uygun tedavi rejiminin başlanmasına hem de gereksiz antibiyotik kullanımınınönlenmesine neden olur. SUMMARYCOMPARISION OF THE RESULT OF SINUS TRACK CULTURE AND BONECULTURE IN CHRON C OSTEOMYELITISMehmet UluğDepartment of Clinical Microbiology and Infectious Diseases,Dicle University Medical Faculty, DiyarbakirPurpose: The infection of bone that contains bone marrow called osteomyelitis, whichwas caused by different microorganisms. In this study, we aimed to determine the diagnosticvalue and accuracy of cultures of material from a sinus track compared with those of culturesof bone specimens have been controversial.Material and Method: Prospective study conducted at Hospital University of Dicle, a1090-bed university based hospital located in Diyarbakir, Turkey. Between May 2005 andSeptember 2006 sinus track cultures were compared with those of bone cultures from 43patients with chronic osteomyelitis.Results: The patients? mean age was 30,6 ± 3,6 year, and 29 (67%) were male and 14(33%) were female. Their mean ESR, CRP and WBC were found 82,7 mm/hour ± 4.4, 122,4mg/dl ± 11, 11099,3/mm3 ± 640 respectively. The high level of CRP and ESH weredetermined meaningful, but WBC number was not meaningful by statistically. Organismsisolated from bone cultures were staphylococcus 72,5% (29/40), Escherichia coli 10% (4/40),Pseudomonas aeruginosa 10% (4/40), Proteus mirabilis 7,5% (3/40) respectively. Cultures ofsinus track and bone specimens gave identical results in 62,7% of patients, with slightly betterconcordance in chronic osteomyelitis caused by staphylococcus 78% than by all otherbacterial species.Conclusion: The correlation between sinus track and bone cultures was 37,3%. Thatmeans, the failure in the treatment at four patients in 10.The value of bone culture in thetherapy of osteomyelitis must be emphasised; it is the only reliable means of determining theresponsible agent, and then basing antibiotic therapy on this. 69
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- 2006
18. Hastane kökenli gram negatif bakterilerde genişlemiş spektrumlu beta-laktamazlar
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Çelen, Mustafa Kemal, Ayaz, Celal, Geyik, Mehmet Faruk, Hoşoğlu, Salih, Uluğ, Mehmet, Dicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Ana Bilim Dalı, Çelen, Mustafa Kemal, Ayaz, Celal, Geyik, Mehmet Faruk, Hoşoğlu, Salih, and Uluğ, Mehmet
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Genişlemiş spektrumlu beta-laktamazlar ,Extended-spectrum beta-lactamase activity ,E-test ,Rational antibiotic use ,Rasyonel antibiyotik kullanımı ,Gram negatif bakteriler ,Gram negative bacteria - Abstract
Dicle Üniversitesi Hastanesi, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Laboratuvarı ve Merkez laboratuvarında iki yıllık sürede (2003-2004) değişik klinik örneklerden soyutlanan ve Centers for Disease Control kriterlerine göre hastane infeksiyonu etkeni olarak kabul edilen 182 Gram negatif bakteride genişlemiş spektrumlu beta-laktamaz (GSBL) oluşturma E-test yöntemi ile araştırılmıştır. Klebsiella spp.’de 24/51 (% 47), Escherichia coli’de 14/42 (% 33), Pseudomonas spp.’de 13/39 (% 33), Acinetobacter spp.’de 4/17, Enterobacter cloacae’de 4/15, Proteus spp.’de 2/11, Serratia marcescens’de 1/3 oranında GSBL saptanmış, 4 Citrobacter freundii’de GSBL saptanmamıştır. 2001 yılında hastanemizde Gram negatif çomaklarda % 31 olan GSBL oluşturma bu çalışmada da % 34 (62/182) olarak belirlenmiş olmasına karşın istatistiksel olarak anlamlı bir fark saptanmamıştır (p>0.05). Özellikle rasyonel olmayan antibiyotik kullanımı ciddi hastane infeksiyonlarına yol açacak dirençli bakterileri öne çıkarmaktadır. Bu önemli sorun, kontrollü antibiyotik kullanımını sağlayacak stratejilere gereksinim olduğunu göstermektedir. Hundred and eighty-two Gram negative bacterial strains isolated in Dicle University Hospital, Infectious Diseases Laboratory and Central Laboratory in two-years period (2003-2004) and assessed as the etiological agents in nosocomial infections according to the Centers for Disease Control criteria were investigated for extended-spectrum beta-lactamase production (ESBL). ESBL production was detected in 24 of 51 (47 %) Klebsiella spp., in 14 of 42 (33 %) Escherichia coli, in 13 of 39 (33 %) Pseudomonas spp., in 4 of 17 Acinetobacter spp., in 4 of 15 Enterobacter clocae, in 2 of 11 Proteus spp., in 1 of 3 Serratia marcescens and in none of 4 Citrobacter freundii strains. The total number of ESBL producing strains was 62 in 182 (34 %). This ratio was 31 % in the year 2001 (p>0.05). Infections with ESBL producing organisms can pose a therapeutic challenge; leading to treatment failure when wrong class of antibiotics are used. As a result it is very important that each hospital should create their rational antibiotic management strategies.
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- 2006
19. AVRUPA BĠRLĠĞĠ ÜYESĠ 13 ÜLKEDE POST-KEYNESYEN PARA ARZININ ĠÇSELLĠĞĠ HĠPOTEZĠNĠN TEST EDĠLMESĠ.
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IġIK, Sayım, ALKIN, Huriye, and ULUĞ, Mehmet
- Abstract
Copyright of Kafkas University, Journal of Economics & Administrative Sciences Faculty / Kafkas Üniversitesi Iktisadi ve Idari Bilimler Fakültesi Dergisi is the property of University of Kafkas, Faculty of Economics & Administrative Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2018
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20. Kronik osteomiyelitli olgularda kemik doku ve burun sürüntü kültürlerinden izole edilen stafilokok türlerinin değerlendirilmesi
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Uluğ, Mehmet, Ayaz, Celal, Çelen, Mustafa Kemal, Dicle Üniversitesi, Tıp Fakültesi, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, and 0-Belirlenecek
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Staphylococcus aureus ,Nazal taşıyıcılık ,Kemik kültürü ,Nasal carriage ,Konik osteomiyelit ,Chronic osteomyelitis ,Bone culture - Abstract
Amaç: Bu çalışmada, kronik osteomiyelitli olgularda nazal S. aureus taşıyıcılığının sıklığı ile bu türlerde metisilin direncinin araştırılması ve stafilokokkal kronik osteomiyelitli olgularda kemik doku ve burun sürüntü kültürü sonuçlarının değerlendirilmesi amaçlanmıştır. Gereç ve yöntem: Kronik osteomiyelitli 43 olgunun kemik kültürleri operasyon esnasında, burun sürüntü kültürleri ise operasyon öncesinde alındı. Örnekler %5 koyun kanlı ve eosin metilen blue agar plaklarına ekimi yapılarak, 370 C’de 24 saat inkübe edildi. Gram pozitif kok morfolojisi gösteren kolonilere katalaz ve koagülaz testleri uygulandı. Tüm S. aureus izolatlarının oksasilin ve diğer bazı antibiyotiklere duyarlılıkları CLSI önerilerine göre disk difüzyon yöntemi ile araştırıldı. Bulgular: Bu çalışmada, Mayıs 2005 ile Eylül 2006 tarihleri arasındaki döneme ait operasyon öncesi alınan burun kültürleri ile operasyon esnasında alınan kemik doku kültürleri retrospektif olarak değerlendirilmiştir. Burun kültürlerinin %72’sinde (31/43) stafilokok türleri tespit edilirken, bu türlerden %58’i (18/31) S.aureus tanımlanmış ve %72,2’sinde (13/18) metisiline direnç görülmüştür. Kemik doku kültüründen ise 29 hastada (%67,4) stafilokok türleri izole edilmiş, bu türlerin %79,3’ü (23/29) S. aureus olarak tanımlanmış ve %52,1’inde metisiline direnç saptanmıştır. İzole edilen stafilokok türlerinde benzerlik oranı 11/29 (%38) iken türlerin çalışılan antibiyotiklere direnç durumları göz önüne alındığında bu oran 7/29 (%24) bulunmuştur. Sonuç: Kronik osteomiyelitli hastalarda nazal S. aureus taşıyıcılığı oranı (%58) topluma ve diğer hasta gruplarına göre daha yüksek bulundu. Bununla birlikte, bu hastalarda sürveyans kültürleri, etken patojenin tespit edilemediği olguların %25’inde, etken hakkında fikir verebilir Objectives: In this study, it was aimed to determine the prevalence of nasal carriage of S. aureus in chronic osteomyelitis, assessed trends in methicillin resistance with time, and evaluated the bone and nasal cultures in staphylococcal chronic osteomyelitis. Materials and methods: Bone and nasal cultures were performed intra-operative and pre-operatively from 43 patients with chronic osteomyelitis. Inoculation was performed on 5% sheep blood and eosine-methylen-blue agar. The samples were incubated at 37°C for 24 hours. Catalase and coagulase tests were performed on Gram positive coccus strains. Antimicrobial susceptibilities of all S. aureus strains were evaluated by disc diffusion method according to CLSI for oxacillin and other antibiotics. Results: In this study pre-operative nasal cultures and intra-operative bone cultures obtained between May 2005 and September 2006 were evaluated retrospectively. Of the 43 nasal cultures, 31 (72%) yielded staphylococcal strain, of these 18 (58%) were S. aureus. Of the 18 S. aureus strains, 13 (72.2%) have methicilline resistance. On the other hand, of the 43 bone cultures, 29 (67.4%) yielded staphylococci strain, of these 23 (79.3%) were S. aureus. Of the 23 S. aureus strains, 52.1% have methicilline resistance. Overall the similarity rate of staphylococcal strains was 38% (11/29), while considering the status of strains resistant to antibiotics; this ratio was 24% (7/29). Conclusions: Nasal S. aureus carriage rate (58%) in patients with chronic osteomyelitis was higher than the community and the other patient groups. However, the surveillance cultures can give knowledge about the causative pathogen of 25% of the culture negative cases.
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- 2012
21. The evaluation of cultures of endotracheal aspirates and isolated bacteria in the diagnosis of ventilator-associated pneumonia
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Uluğ, Mehmet, Çelen, Mustafa Kemal, Geyik, Mehmet Faruk, Hoşoğlu, Salih, and Ayaz, Celal
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bacterial infections and mycoses ,Antibiotic susceptibility ,Endotracheal aspiration ,Ventilator-associated pneumonia - Abstract
Aim: The aim of this study was to determine the ventilator-associated pneumonia (VAP) agents in isolates from endotracheal aspirate samples obtained from patients in intensive care unit (ICU) on mechanical ventilation and their susceptibility to several antibiotics. Material and Methods: Patients that received mechanical ventilation for longer than 48 hours in the ICU were diagnosed as VAP with the clinical and microbiological criteria, were enrolled in this study. Bacteria isolated from the endotracheal aspiration samples of them were identified by conventional methods and Sceptor systems, and their antibiotic susceptibilities were investigated by the National Committee for Clinical Laboratory Standards (NCCLS). Findings: A total of 72 patients were involved in this study and 84 strains were isolated. Among these patients, 12 (14.3%) had polymicrobial etiologic agent. Most commonly encountered microorganisms were Pseudomonas aeruginosa, Staphylococcus aureus and Acinetobacter spp., respectively. Most of the Gram-negative bacteria were susceptible to imipenem, amikacin and ciprofloxacin. Although methicillin resistant S. aureus rate was found %100, glycopeptides resistance was not found. It was determined that 58 (92%) of the Gram-negative bacteria produced ESBL. Results: As a result, VAP is an important and frequently seen infection in ICU. High resistance rates for antibiotics suggested that the treatment of the empirical antibiotics recommended for VAP cases should be updated according to the surveillance data. © 2011 Düzce Medical Journal.
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- 2011
22. Evaluation of Cat Scratch Disease Cases Reported from Turkey between 1996 and 2013 and Review of the Literature
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Uluğ, Mehmet, primary
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- 2015
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23. The evaluation of gram negative bacilli isolated from inpatiens and its antibiotic resistance
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Özmen, Esen, Geyik, Mehmet Faruk, Uluğ, Mehmet, Çelen, Mustafa Kemal, Hoşoğlu, Salih, and Ayaz, Celal
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Genel ve Dahili Tıp - Abstract
Amaç: Gram negatif bakteri (GNB)’lerde antibiyotik direnci tüm dünyada giderek artmaktadır. Bu çalışmada, yatan hastalardan izole edilen GNB’lerin bazı antibiyotiklere karşı direnç oranlarını belirleyerek, ampirik antibiyotik tedavisi için yol gösterici sonuçlar elde etmek amaçlandı. Materyal ve Metod: Bu çalışmada, Dicle Üniversitesi Tıp Fakültesi Hastanesinde Mayıs 2003 ile Nisan 2005 tarihleri arasında, yatan hastalarda çeşitli klinik örneklerden izole edilen 898 GNB incelendi. Antibiyotik direncini saptamak için mikrodilüsyon yöntemi kullanıldı. Bulgular: En sık izole edilen GNB’ler sırasıyla Escherichia coli (n282), Enterobacter spp. (n215), P. aeruginosa (n101), Klebsiella spp. (n95), S. maltophilia (n69) ve Acinetobacter spp. (n52) idi. Genel antibiyotik direnç oranları seftriakson için %73, sefotaksim için %68, seftazidim için %63, trimetoprim-sulfametaksazol için %60, siprofloksasin için %51, amikasin için %20, imipenem için %3 ve meropenem için %2 olarak tespit edildi. Bu çalışmada, izole edilen GNB’lerin üçüncü kuşak sefalosporinlere, trimetoprim-sulfametaksazole ve siprofloksasine karşı direnç oranları çalışılan diğer antibiyotiklere göre daha yüksek bulundu. Sonuç: Uygun ampirik antibiyotik tedavisi için her hastanenin kendi direnç oranlarını düzenli aralıklarla izlemesi gerekmektedir. Yapılacak sürveyans çalışmaları ampirik tedavi yaklaşımı için yol gösterici olacaktır. Aim: Resistance to gram negative bacilli is increasing all over the world. In this study, the resistance of gram negative bacilli, which were isolated from inpatients, was evaluated for selected antibiotics. The aim of this study was to acquire the significant results for empiric therapy. Material and Method: Eight hundered ninety eight strains which were isolated from inpatients were investigated between May 2003 and April 2005 from clinical speciments at Dicle University Hospital, Diyarbakir. The microdiluation test was used to determine for antibiotics resistance. Findings: Escherichia coli (n282), Enterobacter spp. (n215), Pseudomonas aeruginosa (n101), Klebsiella spp. (n95), Stenotrophomanas maltophilia (n69) and Acinetobacter spp. (n52) were the most frequent isolates. The resistance ratio among whole isolates against ceftriaxone was 73%, cefotaxime 68%, ceftazidime 63%, trimetoprim/sulfamethoxazole 60%, ciprofloksasin 51%, amikasin 20%, imipenem 3% and meropenem 2%. The resistance to the third generation cephalosporins, trimetoprim/sulfamethoxazole and ciprofloxacin was found higher than other antibiotics in this study. Results: In conclusion, antimicrobial resistance must be monitored for each hospital for a reasonable empirical antibiotic therapy. Surveillance studies might be useful for empirical treatment approach.
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- 2010
24. NASOPHARYNGEAL CARCINOMA IN THE ETIOLOGY OF FEVER OF UNKNOWN ORIGIN
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Uluğ, Mehmet, Çelen, Mustafa Kemal, Geyik, Mehmet Faruk, Tekin, Recep, and Ayaz, Celal
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Fever ,lymphadenopathy ,nasopharyngeal carcinoma - Abstract
WOS: 000281404900018, Fever of unknown origin is defined as a temperature higher than 38.3 degrees C lasting three weeks or longer and not beind diagnosed even after one week of study in-hospital settings. Infections and malignancies had been the most common causes of fever of unknown origin overall. Nasopharyngeal carcinoma,constituting less than 0.03% of all malignant tumors and only 2% of all head and neck cancer. Ebstein Barr virus infection consumption of smoked and salted fish and vitamin-C deficient diet have been blamed in its etiology. In this study,we present two cases who were admitted to our clinic with fever of unknown origin initially and later diagnosed with nasopharyngeal carcinoma atypically progressing.
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- 2010
25. The evaluation of geriatric infections: Dicle experience [Geri?atri?k i?nfeksi?yonlarin de?erlendi?ri? lmesi?: Di?cle deneyi?mi?]
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Uluğ, Mehmet, Çelen, Mustafa Kemal, Geyik, Mehmet Faruk, Hoşoğlu, Salih, and Ayaz, Celal
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Elderly patients ,Infection ,Risk factors ,Sepsis - Abstract
• Objective: Although successes have been achieved in the treatment of the infectious diseases with antibiotics in nowadays, infectious diseases are still serious problem in the elderly. This study was conducted in order to determine the pattern of clinical infectious diseases in hospitalized elderly patients. • Material and Method: In this study, the data of all elderly patients aged 65 and older, were hospitalized to our clinic between May 2000 and May 2005 were evaluated retrospectively. We reviewed 301 patients for diagnostic studies, risk factors, isolated microorganisms and morbidity and mortality rates. • Results: Infections as a cause of hospitalization were identified as the following frequency; sepsis (19.2%), pneumonia (17.9%), acute gastroenteritis (16.9%), acute bacterial meningitis (5.3%) and urinary tract infection (3.6%), respectively. E. coli was the most isolated microorganism in these patients. Hypertension, chronic obstructive pulmonary disease and diabetes were seen as risk factors in our patients. Seventy-three patients died during hospital stay due to their infection and chronic diseases. • Conclusion: Under diagnosis of the elderly diseases is very common due to many factors related to elderly, family members and health workers. Prognosis is rather worse especially in sepsis due to pneumonia and urinary tract infections.
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- 2010
26. THE EVALUATION OF GERIATRIC INFECTIONS DICLE EXPERIENCE
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Uluğ, Mehmet, Çelen, Mustafa Kemal, Geyik, Mehmet Faruk, Hoşoğlu, Salih, and Ayaz, Celal
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sepsis ,risk factors ,Infection ,elderly patients - Abstract
WOS: 000285677300007, Objective Although successes have been achieved in the treatment of the infectious diseases with antibiotics in nowadays infectious diseases are still serious problem in the elderly This study was conducted in order to determine the pattern of clinical infectious diseases in hospitalized elderly Patients C. Material and Method In this study the data of all elderly patients aged 65 and older were hospitalized to our clinic between May 2000 and May 2005 were evaluated retrospectively We reviewed 301 patients for diagnostic studies risk factors isolated microorganisms and morbidity and mortality rates Results Infections as a cause of hospitalization were identified as the following frequency sepsis (19 2%) pneumonia (17 9%) acute gastroenteritis (16 9%) acute bacterial meningitis (5 3%) and urinaty tract infection (3 6%) respectively E colt was the most isolated microorganism in these patients Hypertension chronic obstructive pulmonary disease and diabetes were seen as risk factors in our patients Seventy three patients died during hospital stay due to their infection and chronic diseases Conclusion Under diagnosis of the elderly diseases is very common due to many factors related to elderly family members and health workers Prognosis is rather worse especially in sepsis due to pneumonia and urinary tract infections
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- 2010
27. Stevens-johnson syndrome caused by combined use of lamotrigine and fluoxetine and review of the literature
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Uluğ, Mehmet, Uluğ, Nuray Can, Çelen, Mustafa Kemal, Geyik, Mehmet Faruk, and Ayaz, Celal
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Stevens - Johnson syndrome ,stomatognathic diseases ,Fluoxetine ,Lamotrigine ,Medical treatment - Abstract
WOS: 000285419600015, Stevens-Johnson syndrome (SJS) is a rare, life-threatening acute allergic drug reaction presenting with target lesions and blebs of epidermis. Although a variety of etiologies such as infections and underlying malignancies have been implicated as potential causes of SJS, drugs remain the predominant inciting agent. This report presents a SJS case due to combined use of lamotrigine and fluoxetine. A 41-year-old man was admitted to our clinic with fever, skin eruptions (especially on the face and trunk) and lesions around the mouth. The patient's history revealed lamotrigine and fluoxetine use during the previous three weeks for major depression. Dermatological examination revealed a typical clinical picture of SJS; his psychotropic medications were all stopped. While topical and ocular prednisolone (1mg/kg/day) cares were initiated, steroid dosage was reduced within 15 days. The condition of patient rapidly improved through this treatment. Effective management of SJS begins with prompt recognition of the entity, combined with attention to each of the major organs that may be affected, potential comorbidities and withdrawal of all potentially causative drugs. Clinicians should bear in mind the possibility that drugs with potential risk in developing SJS must be used carefully.
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- 2010
28. The evaluation of gram negative bacilli isolated from inpatiens and its antibiotic resistance [Yatan hastalardan i?zole edilen gram negatif bakteriler ve antibiyotik dirençlerinin de?erlendirilmesi]
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Özmen, Esen, Geyik, Mehmet Faruk, Uluğ, Mehmet, Çelen, Mustafa Kemal, Hoşoğlu, Salih, and Ayaz, Celal
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Antibiotic ,Gram negative bacilli ,Inpatient - Abstract
Aim: Resistance to gram negative bacilli is increasing all over the world. In this study, the resistance of gram negative bacilli, which were isolated from inpatients, was evaluated for selected antibiotics. The aim of this study was to acquire the significant results for empiric therapy. Material and Method: Eight hundered ninety eight strains which were isolated from inpatients were investigated between May 2003 and April 2005 from clinical speciments at Dicle University Hospital, Diyarbakir. The microdiluation test was used to determine for antibiotics resistance. Findings: Escherichia coli (n=282), Enterobacter spp. (n=215), Pseudomonas aeruginosa (n=101), Klebsiella spp. (n=95), Stenotrophomanas maltophilia (n=69) and Acinetobacter spp. (n=52) were the most frequent isolates. The resistance ratio among whole isolates against ceftriaxone was 73%, cefotaxime 68%, ceftazidime 63%, trimetoprim/sulfamethoxazole 60%, ciprofloksasin 51%, amikasin 20%, imipenem 3% and meropenem 2%. The resistance to the third generation cephalosporins, trimetoprim/sulfamethoxazole and ciprofloxacin was found higher than other antibiotics in this study. Results: In conclusion, antimicrobial resistance must be monitored for each hospital for a reasonable empirical antibiotic therapy. Surveillance studies might be useful for empirical treatment approach. © 2010 Düzce Medical Journal.
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- 2010
29. Brucellar epididymo-orchitis in southeastern part of Turkey: an 8 year experience
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Celen, Mustafa Kemal, Ulug, Mehmet, Ayaz, Celal, Geyik, Mehmet Faruk, and Hosoglu, Salih
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- 2010
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30. Splenektomi yapılan hastaların aşılanmalarının ve bu konudaki bilgilerinin değerlendirilmesi
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ULUĞ, Mehmet, primary, ASLAN, Vahap, additional, YILMAZ, Namık, additional, and DOLU, İbrahim, additional
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- 2014
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31. In Organizations the effect of the group management on total quality management -an application
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Uluğ, Mehmet, Genç, Nurullah, and İşletme Ana Bilim Dalı
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Organizations ,İşletme ,Groups ,Quality circles ,Total quality management ,Group management ,Quality ,Business Administration - Abstract
ÖZET YÜKSEK LİSANS TEZİ ÖRGÜTLERDE GRUP YÖNETİMİNİN TOPLAM KALİTE YÖNETİMİ ÜZERİNE ETKİSİ -BİR UYGULAMA- Mehmet ULUĞ Danışman : Prof.Dr. Nurullah GENÇ 2002, Sayfa: 179 + XIV Jüri : Prof.Dr. Nurullah GENÇ Prof.Dr. Dursun BİNGÖL Prof.Dr. Muammer YAYLALI Bu çalışmanın amacı, özellikle 1980'li yıllardan başlayarak tüm Dünyada gittikçe önem kazanarak oldukça fazla uygulama alanı bulan Toplam Kalite Yönetimi ve bu anlayışın olmazsa olmazlarından olan grup çalışmalarının önemini ve uygulama düzeyini ortaya koymak, etkin yönetilen grupların örgüte olan katkılarını tespit etmektir. Çalışma üç bölümden oluşmaktadır. İlk iki bölüm teoriyle ilgili bilgilerden, üçüncü bölüm ise teoride ele alınan konuların uygulanma düzeylerinin test edilmesinden ibarettir. Birinci bölümde, genel kavramlar adı altında gruplar ve Toplam Kalite Yönetimi konuları ile ilgili genel bilgiler verilmiştir. İkinci bölümde, Toplam Kalite Yönetiminin temel özelliklerinden biri olan gruplar, grup çalışmaları ve yönetimi, Kalite Çemberleri ve grup çalışma teknikleri -beyin fırtınası vs- incelenmiştir. Üçüncü bölümde ise, yöneticilerin gruplarla ilgili algılarını test etmek amacıyla yapılan uygulama yer almıştır. Çalışmanın sonunda; yöneticilerin Toplam Kalite Yönetiminin özüne uygun hareket ettikleri, başarı için grup çalışmalarından mutlaka yararlanılması gerektiği ve bunlardan gereği gibi faydalandıkları tespit edilmiştir. VI ABSTRACT MASTER THESIS IN ORGANIZATIONS THE EFFECT OF THE GROUP MANAGEMENT ON TOTAL QUALITY MANAGEMENT-AN APPLICATION- Mehmet ULU? Supervisor: Prof.Dr. Nurullah GENÇ 2002, Page: 179 + XIV Jury : Prof.Dr. Nurullah GENÇ Prof.Dr. Dursun BİNGÖL Prof.Dr. Muammer YAYLALI The aim of this study is to put forward the importance and the application level of the total quality management, which have had a considerable application field especially from the 1980's on by gaining importance increasingly all over the world, and group studies that are one of the essentials of that mentality and determine the contributions of the effectively managed groups to the organization. The study consists of three parts. The first two parts include information concerning the theory, and the third part includes information on the testing of application levels of the subjects discussed in the theory. In the first part, general information, under the title of `General Concepts`, on groups and total quality management is given. In the second part; groups that are one of the main characteristics of Total Quality Management, group studies and management, Quality Circles and techniques of group study - brainstorming, etc.- is investigated. In the third part is the application that was performed in order to test the perceptions of the managers about the groups. As a result of the study, it is concluded that managers acted in accordance with the essence of the Total Quality Management; that for success, group studies are to be made use of; and that managers have made use of those properly. 193
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- 2002
32. A viral infection of the hands: Orf
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Uluğ, Mehmet, primary
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- 2013
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33. Evaluation of 44 Kikuchi-Fujimoto Disease Cases Reported from Turkey Between 2000-2010 with Pooled Analysis Method
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ULUĞ, Mehmet, primary
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- 2013
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34. The evaluation of staphylococci strains isolated from nasal and bone cultures in patients with chronic osteomyelitis
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Uluğ, Mehmet, primary
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- 2012
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35. Pulmonary Involvement in Brucellosis
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Uluğ, Mehmet, primary and Can-Uluğ, Nuray, additional
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- 2012
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36. A case report and literature review: osteomyelitis caused by community-associated methicillin resistant Staphylococcus aureus
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Uluğ, Mehmet, primary, Ayaz, Celal, additional, and Celen, Mustafa Kemal, additional
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- 2011
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37. Metoklopramid kullanımına bağlı gelişen akut distoni olgusu / A case report of acute dystonia caused by a therapeutic dose of metoclopramide
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Uluğ, Nuray Can, primary and Uluğ, Mehmet, additional
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- 2011
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38. An unusual presentation of brucellosis: acute hepatitis
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Uluğ, Mehmet, primary, Celen, Mustafa Kemal, additional, and Ayaz, Celal, additional
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- 2010
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39. Acute hepatitis: a rare complication of Epstein-Barr virus (EBV) infection
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Uluğ, Mehmet, primary, Çelen, Mustafa Kemal, additional, Ayaz, Celal, additional, Geyik, Mehmet Faruk, additional, and Hoşoğlu, Salih, additional
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- 2010
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40. Adult-onset Still's Disease in the Etiology of Fever of Unknown Origin and Review of the Literature
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Uluğ, Mehmet, primary and Can Uluğ, Nuray, additional
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- 2010
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41. İki Kedi Tırmığı Hastalığı Olgusu: Nadir Görülen Zoonotik Bir İnfeksiyon Hastalığı.
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Uluğ, Mehmet, Aslan, Vahap, Arık, Deniz, Yılmaz, Namık, and Üstün, Melek
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Cat scratch disease is a zoonotic infectious disease caused by Bartonella henselae. It is usually observed in children and young adults who have a history of contact with cats. It is an important cause of infectious lymphadenopathies and the most common involvement sites are axillary, cervical and inguinal lymph nodes. In this report, we present two male adult cases who complained of axillary and inguinal lymphadenopathy, respectively. Both have a history of contact with cats. The excisional biopsies of the lymphadenopathies were performed. The histopathological examination revealed the granulomatous lymphadenitis, which is consistent with cat scratch disease. Investigation of the patients' serum samples for the presence of specific B. henselae antibodies by indirect immunofluorescence assay revealed B. henselae IgM type antibodies at a titer of 1/40 and 1/320, respectively. The patients were successfully treated with azithromycin. Since, cat scratch disease is a rare infection of adults, it should be taken into consideration in the patients suffering from regional lymphadenopathy with history of direct contact with cats. [ABSTRACT FROM AUTHOR]
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- 2014
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42. Türkiye'de 2000-2010 Yılları Arasında Yayımlanan 44 Kikuchi-Fujimoto Hastalığğ Olgusunun Havuz Analiz Yöntemi ile Değerlendirilmesi.
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ULUĞ, Mehmet
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- 2013
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43. Hematolojik Malignitesi Olan Hastalarda Febril Nötropeni Atakları Sırasında Alınan Burun Kültürlerinin Değerlendirilmesi.
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Uluğ, Mehmet, Ayaz, Celal, and Kemal Çelen, Mustafa
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FEBRILE neutropenia , *STAPHYLOCOCCUS aureus , *STAPHYLOCOCCUS aureus infections , *DISEASE prevalence , *OXACILLIN , *MICROBIAL cultures - Abstract
Aim: Febrile neutropenia is a common complication in patients receiving cancer treatment. According to the results of several investigations, bacterial infections are the most common causes of morbidity and mortality in these patients. In this study, we aimed to determine the prevalence of nasal carriage of S. aureus in patients with febrile neutropenia, to assess the frequency of methicillin resistant S. aureus, and to compare the blood and nasal cultures in these patients. Methods: Nasal and blood cultures were performed in 51 patients with hematological malignancies during febrile neutropenic episodes. Antimicrobial susceptibilities of all S. aureus and Gram-negative strains were evaluated by disc diffusion method according to the National Committee for Clinical Laboratory Standards (NCCLS) for oxacillin and several other antibiotics. Results: In this study, blood and nasal cultures obtained between March 2006 and September 2006 were evaluated retrospectively. The overall nasal S. aureus carriage rate was 23.5%. On the other hand, of all blood cultures performed in 51 patients, nine (17.5%) were positive and the bacteria were not isolated in 87.5% of patients. The overall compliance rate of strains isolated from both blood and nasal cultures was 17.5%, while it was 11.7% when considering the status of strains resistant to antibiotics studied. Conclusion: It is concluded that, the surveillance cultures made occasionally in patients with febrile neutropenia may give an idea to the physicians in cases in which the causative pathogen cannot be determined. [ABSTRACT FROM AUTHOR]
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- 2012
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44. Toplum Kökenli Üriner Sistem İnfeksiyonu Tanısı Alan Yaşlı Hastalarda İdrar Kültürü Sonuçlarının ve Ampirik Antibiyotik Tedavisi Yaklaşımının İrdelenmesi.
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Uluğ, Mehmet and Gül, İsmail
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ANTIBIOTICS , *AMOXICILLIN , *CANDIDA , *CIPROFLOXACIN , *CO-trimoxazole , *DISEASE susceptibility , *DRUG resistance in microorganisms , *ENTEROCOCCUS , *ESCHERICHIA coli , *GENTAMICIN , *GRAM-negative bacteria , *GRAM-positive bacteria , *KLEBSIELLA , *MICROBIAL sensitivity tests , *PROTEOLYTIC enzymes , *PSEUDOMONAS , *PUBLIC health surveillance , *URINARY tract infections , *RETROSPECTIVE studies , *NITROFURANTOIN , *PHARMACODYNAMICS , *OLD age ,URINE collection & preservation - Abstract
Objective: Urinary tract infection is one of the most common bacterial diseases in elderly patients. The objective of this study is to determine the antibiotic resistance rates against first-line antibiotics used for the treatment of community-acquired urinary tract infections in elderly patients at our hospital, and use the results as guidance for empirical antibiotic therapy. Methods: In this study, data on all elderly patients aged 65 and older who were followed and treated in our hospital between March 2010 and March 2012 were evaluated retrospectively. Results: 406 microorganisms were isolated from the urine cultures of 401 patients included in the study, because 5 (1.2%) patients harbored two microorganisms. Of the 406 microorganisms, 320 (78.8%) were Gram-negative bacilli, 72 (17.7%) were Gram-positive cocci and 14 (3.5%) were Candida spp. Escherichia coli (n=262, 64.5%), Klebsiella pneumoniae (n=27, 6.6%), and Pseudomonas aeruginosa (n=17, 4.1%) were the most common among Gram-negatives, and Enterococcus faecalis (n=36, 8.9%) and coagulase-negative staphylococci (n=25, 6.2%) were the most common among Gram-positives. Susceptibility rates of E. coli strains were 89% for nitrofurantoin, 81% for trimethoprim-sulfamethoxazole, 77% for amoxicillin-clavulanic acid, 70% for gentamicin and 66% for ciprofloxacin. Conclusions: Antimicrobial resistance must be monitored at each hospital in order to make correct choices for empirical antibiotic therapy. Surveillance studies are helpful for this purpose. In conclusion, nitrofurantoin and trimethoprim-sulfamethoxazole can safely be used for the empirical treatment of urinary tract infections in elderly patients. [ABSTRACT FROM AUTHOR]
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- 2012
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45. Ameliyathane ve Yoğun Bakım Personelinde Nazal Staphylococcus Aureus Taşıyıcılığının Araştırılması.
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Uluğ, Mehmet
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DISEASE prevalence , *STAPHYLOCOCCUS aureus , *ANTIBIOTICS , *METHICILLIN , *OPERATING rooms , *INTENSIVE care units - Abstract
Aim: In this study, we aimed to investigate the prevalence of nasal carriage of Staphylococcus aureus in our hospital staff, and antibiotic susceptibility of these strains to methicillin and some other antibiotics. Methods: In this study, involving personnel working in operating room, neonatal and intensive care units of our hospital, nose cavity swab samples were taken from 81 subjects using cotton swabs soaked into serum physiologic. Single colony inoculation was performed on 5% sheep blood agar. The samples were incubated at 37oC for 24 hours. The Catalase and coagulase tests were performed on the strains which showed gram-positive cocci. We evaluated antimicrobial susceptibility of all S. aureus strains to oxacillin and several other antibiotics by disc diffusion method according to the Clinical and Laboratory Standards Institute (CLSI) recommendations.. Results: Nasal S. aureus carrier was detected in 21 subjects (25.9%). Among all S. aureus isolated from nasal area, nine (11.1%) were methicillin-resistance and 12 (14.8%) were methicillin-susceptible S. aureus. When the occupation was considered, the carriage rates were 20.8% among doctors, 25% among auxiliary health-care workers and 29.7% among health-care workers other than doctors. There was no significant difference in carriage rate between these groups (p=0.239). The isolated strains showed no resistance to mupirocin and teicoplanin. Intranasal administration of mupirocin to all carriers for five days resulted in elimination of staphylococci with a success rate of 100%. Conclusion: According to these results, we assume that the nasal carriage of methicillin-resistant S. aureus is not an important issue in our hospital. However, it was concluded that topical mupirocin is an effective agent to be used securely in the elimination of S. aureus colonization in nasal carriers. (The Medical Bulletin of Haseki 2012; 50: 48-52) [ABSTRACT FROM AUTHOR]
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- 2012
46. The Efficacy of an Antibiotic Control Team on Rational Antibiotic Use: Cost-Utility Analysis and Achievement in Surgical Prophylaxis.
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Uluğ, Mehmet, Kemeç, Özgül, and Can-Uluğ, Nuray
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Objective: Antibiotics are the most frequently used drugs in our country, as being all over the world. It has been shown that the rate of inappropriate use of antibiotics is around 40% to 60% in hospitals. Excessive and inappropriate use of antibiotics causes emergence of resistant organisms, significant adverse effects, increased costs and increased morbidity and mortality. Methods: This study was carried out at Midyat State Hospital between June 2007 and June 2008. The period of time between June 2006 and June 2007 and between June 2007 and June 2008 are defined as Period I and II, respectively. Antibiotics which were given to inpatients and for surgical prophylaxis were followed up. Subsequently, usage ratios of antibiotics in Period I and II were compared for a cost-utility analysis. Results: The total cost of inappropriate antibiotic use per year was calculated as 55 750.4 TL in our hospital. However, the most frequent cause of inappropriate use in surgical prophylaxis was related to prolonged use of prophylactic antibiotics (16.2%). Conclusions: Several strategies for regulating antimicrobial prescribing practices may be proposed, such as formulary replacement or restriction, healthcare provider education, feedback activities, and approval from an infectious diseases physician. However, a multidisciplinary antibiotic team organized for hospitals to approve the appropriate antibiotic use may be another alternative. [ABSTRACT FROM AUTHOR]
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- 2012
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47. Antibiyotik Kontrol Ekibinin Akılcı Antibiyotik Kullanımına Etkisi: Maliyet Kullanım Analizi ve Cerrahi Profilakside Sağlanan Başarı.
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Uluğ, Mehmet, Kemeç, Özgül, and Can-Uluğ, Nuray
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ANTIBIOTICS , *COST effectiveness , *DRUG prescribing , *OPERATIVE surgery , *PHYSICIAN practice patterns , *ANTIBIOTIC prophylaxis - Abstract
Objective: Antibiotics are the most frequently used drugs in our country, as being all over the world. It has been shown that the rate of inappropriate use of antibiotics is around 40% to 60% in hospitals. Excessive and inappropriate use of antibiotics causes emergence of resistant organisms, significant adverse effects, increased costs and increased morbidity and mortality. Methods: This study was carried out at Midyat State Hospital between June 2007 and June 2008. The period of time between June 2006 and June 2007 and between June 2007 and June 2008 are defined as Period I and II, respectively. Antibiotics which were given to inpatients and for surgical prophylaxis were followed up. Subsequently, usage ratios of antibiotics in Period I and II were compared for a cost-utility analysis. Results: The total cost of inappropriate antibiotic use per year was calculated as 55 750.4 TL in our hospital. However, the most frequent cause of inappropriate use in surgical prophylaxis was related to prolonged use of prophylactic antibiotics (16.2%). Conclusions: Several strategies for regulating antimicrobial prescribing practices may be proposed, such as formulary replacement or restriction, healthcare provider education, feedback activities, and approval from an infectious diseases physician. However, a multidisciplinary antibiotic team organized for hospitals to approve the appropriate antibiotic use may be another alternative. [ABSTRACT FROM AUTHOR]
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- 2012
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48. An unusual cause of cervical lymphadenopathy: Kikuchi-Fujimoto disease.
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Uluğ, Mehmet and Aslan, Vahap
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LYMPHADENITIS , *ETIOLOGY of diseases , *LYMPHATIC diseases , *VIRUS diseases , *PARASITIC diseases - Abstract
Kikuchi-Fujimoto disease (KFD), also known as histiocytic necrotizing lymphadenitis, is an uncommon clinical and pathological self-limited feature of benign prognosis that may mimic many other diseases diagnosed chiefly in young adults. The etiology of the disease is unknown although several investigators postulate viral, parasitic and autoimmune etiologies. The most common symptoms are cervical lymphadenopathy and fever. Diagnosis is usually rendered with excisional biopsy of lymph nodes and through histopathological findings. Non-steroidal anti-inflammatory drugs are used for the treatment. In this report, two cases of KFD without any associated infectious and/or non-infectious conditions were presented. [ABSTRACT FROM AUTHOR]
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- 2012
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49. Kronik hepatit B hastalarında serum total magnezyum düzeyi.
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Uluğ, Mehmet, Çelen, Mustafa Kemal, Ayaz, Celal, and Selek, Şehabettin
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HEPATITIS B treatment , *SERUM albumin , *GRASS tetany , *MAGNESIUM in the body , *BLOOD plasma , *TRACE elements - Abstract
Objective: Magnesium (Mg) is a trace element plays an important role in oxidative stress and redox potentials which were effective in the emergence of liver damage. The aim of this study was to evaluate serum total Mg level in chronic hepatitis B patients because the clinical findings of chronic hepatitis B and hypomagnesemia are similar. Methods: This study was carried out in 32 patients with chronic hepatitis B and asymptomatic HBs Ag carrier (n=37) who were followed at the Departments of Infectious Diseases of Dicle University Medical School and Midyat State Hospital, between April 2007 and August 2008, and in 35 healthy controls. Results: We were not detected significant differences between three groups, included to the study, in serum albumin and total magnesium levels (p=0.06 and p=0.22). Conclusion: In conclusion, the serum total magnesium level was determined within normal limits in chronic hepatitis B patients and asymptomatic HBs Ag carrier. [ABSTRACT FROM AUTHOR]
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- 2011
50. Kene Isırması Nedeniyle Başvuran Olguların Epidemiyolojik, Klinik ve Laboratuvar Bulgularının İrdelenmesi.
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Uluğ, Mehmet
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TICK-borne diseases , *LEG abnormalities , *FEVER , *FATIGUE (Physiology) - Abstract
Objective: Tick-borne diseases including Crimean-Congo haemorrhagic fever (CCHF) pose a serious epidemiological problem all over the world. The aim of this study is to determine the demographic properties of the reported cases with a tick bite and to evaluate their results of follow up and investigations. Methods: Age, sex, complaints at admission and on following days, epidemiological history, information on who, when and how removed the tick, bitten region and laboratory findings of patients seen in the Midyat State Hospital due to tick bites between May 2007 and August 2008 were recorded Results: Mean age of 61 patients admitted to the hospital was 18.2±7.1. Lower extremities (57.1%) were the most common sites bitten. Tick bites were most commonly seen in June, July, and August. Physical and laboratory findings were normal except for fever in four patients. In four patients with fever, a rapid defervescence was observed during follow up. In three patients, another infectious disease was also diagnosed. Their serum samples were found negative for CCHF virus. Conclusions: In the majority of tick bites, no symptoms develop. Asymptomatic patients with tick bite should be informed about CCHF and followed until the end of its presumed incubation period. This study revealed that it is not necessary to hospitalize the patients and perform the laboratory tests after removal of ticks. Instead, it is more appropriate to apply for health care if symptoms such as fever, headache, fatigue, nausea and vomiting develop within 10 days. [ABSTRACT FROM AUTHOR]
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- 2011
- Full Text
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