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Over the past 20 years, we observed an increasing demand of precise and reliable experimental nuclear data in a number of scientific research fields like nuclear astrophysics, basic nuclear physics, nuclear medicine, geoscience, super heavy element research, and others. This demand induces also in an increasing number of requests for high-quality sample material in sufficient amounts and well-known isotopic composition, manufactured in a shape suitable for the specific envisaged application. The desired samples very often represent or contain rare radioactive isotopes, which are very exotic and available in limited amounts only. In dependence on their activity and/or dose rate, the handling of such samples can be extremely challenging. Thus, only a handful of laboratories worldwide are allowed and capable to work with this kind of material. Correspondingly high is the number of requests and waiting lists for sample and target preparation, even if the isotope itself is available in sufficient amounts.

In der modernen Therapie des komplexen regionalen Schmerzsyndroms (CRPS) hat sich ein multimodales Behandlungskonzept durchgesetzt. Neben Medikamenten und Psychotherapie zahlen die Physio- und Ergotherapie (zusammen: Handtherapie) zu den Basistherapieformen. Trotz dieses hohen Stellenwertes in der Behandlung des CRPS sind die einzelnen Anwendungsformen der Handtherapie nur wenig wissenschaftlich untersucht und ihr Einsatz kaum standardisiert.

Die GALERIA Kaufhof GmbH verdankt ihren erfolgreichen Weg vom kleinen Textilgeschaft zum Unternehmen mit Weltruf Menschen mit Ideen und Visionen. Nicht nur durch die Mitarbeiterzahl von rund 21.500, sondern auch durch die komplexen Organisationsstrukturen und der damit einhergehenden Vielzahl an Karriere- und Entwicklungsmoglichkeiten nimmt die Personalarbeit einen besonders hohen Stellenwert im Unternehmen ein. Aufgrund der zunehmenden Komplexitat und Dynamik der Markte und angesichts des demografischen Wandels haben sich allerdings in den letzten Jahren die Anforderungen an die Personalarbeit stark verandert.

Purpose Autologous blood donation is not routinely recommended for all cases of orthognathic surgery. The aim of this study was to evaluate the factors for blood loss during bimaxillary osteotomies that might indicate preoperative blood donation. Patients and Methods In a prospective study, 127 consecutive patients undergoing bimaxillary surgery within a 14-month period were examined for hemoglobin and hematocrit reduction. Possible factors for intraoperative blood loss such as operating time, application of hydroxyethyl starch in segmental osteotomies, experience of the surgeon, and additional procedures (genioplasty, malar osteotomy, iliac crest graft) were statistically analyzed. Results The experience of the surgeon had no influence on the blood loss. Operating time and Quick value correlated significantly with hemoglobin and hematocrit drop after surgery. There was no difference between 1-piece maxilla cases with or without additional procedures and segmental maxilla cases without additional procedures. Only for the group of patients with segmental osteotomies and additional procedures was a significant higher blood loss found. Two patients (1.6%) received 1 unit of blood. Conclusion For patients undergoing bimaxillary osteotomies with segmentation of the maxilla and additional procedures, a preoperative donation of autologous blood should be considered.

The metabolism and excretion of orally administered or injected [14C]chlorphentermine has been studied in man, rhesus monkey, marmoset, rabbit, guinea-pig and rat. These species excreted 55–95% of the administered radioactivity in the urine over 5 days. Two metabolites were characterised by thin-layer and paper chromatography, gas-liquid chromatography and g.c.-m.s. and these were N-hydroxychlorphentermine and 1-(4'-chlorophenyl)-2-methyl-2-nitropropane. There are marked species differences in the excretion of N-oxidation products which were found in the urine of human volunteers. rhesus monkeys, rabbits and guinea-pigs, but not in the urine of marmosets or rats. The rat, rabbit and marmoset also excreted an unidentified unstable acid-labile precursor of chlorphentermine. The results are discussed in relation to the toxicity of the drug and to the metabolism of amphetamines in general.