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Background and aims: The C‐reactive protein to albumin ratio (CAR) is a novel parameter that has been reported as a significant prognostic marker in some diseases. The purpose of the present research was to investigate the predictive value of this ratio with regard to nutritional status in geriatric patients. Methods and results: A total of 154 geriatric patients (age ≥65 years) who consecutively presented to the internal medicine outpatient clinic were included in this cross‐sectional study. The Mini Nutritional Assessment (MNA) was used as a reference to determine the nutritional status of the patients. Based on the MNA results, the patients were divided into two groups: normal nutrition and malnourished or at risk of malnutrition. The median CAR of malnourished patients or those at risk of malnutrition was significantly higher than that of patients with normal nutritional status (p =.012). A significant negative correlation was also observed between the MNA score and the CAR (r = −0.196, p =.015). The receiver operating characteristic curve analysis indicated that the CAR was a significant predictor of malnourishment or the risk of malnutrition (p =.012). Conclusion: The CAR could predict which geriatric patients were malnourished or at risk of malnutrition. CAR may be used as a new tool in the nutritional screening of geriatric patients. [ABSTRACT FROM AUTHOR]

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Purpose: Idiopathic Parkinson's Disease (PD) is a chronic, progressive, neurodegenerative disease affecting basal ganglia, especially the substantia nigra pars compacta, and dopaminergic neurons in the brain stem. Although PD is defined as a movement disorder with motor symptoms, it also affects many systems such as limbic, autonomic, gastrointestinal, and genitourinary systems. The aim of our study is to evaluate the frequency of NMS in PD, which is often overlooked in clinical practice and has serious effects on patients' quality of life. Method: A total of 97 patients were included in the study, 31 of whom were in the mild stage, 30 in the moderate stage, and 36 in the severe stage. REM sleep behavior disorder (RBD), constipation, presence of hyposmia-anosmia, history of appendectomy and excessive daytime sleepiness, depression, orthostatic hypotension, apathy, forgetfulness, hallucinations, sleep problem, pain, fatigue, dizziness, and frequent urination findings have been noted from patients files. Results: There was no significant difference (p >0,05) between the rates of appendectomy, prodromal stage symptoms, and NMS between genders (Table 2). Only forgetfulness, dreaming and fatigue were found to be statistically significantly (p<0,05) lower in mild-stage PD patients than in the moderate and severe stages. Conclusion: In conclusion, NMS consists of many neuropsychiatric, autonomic, and sensory symptoms that can be seen in every stage of PD from the prodromal stage to the severe stage, and they increase the disability caused by the motor findings of PD and decrease the quality of life. [ABSTRACT FROM AUTHOR]

Copyright of Sakarya Tıp Dergisi is the property of Sakarya Tip Dergisi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: This study aimed to evaluate the utility of the CHA2DS2-VASc score for predicting futile recanalization among patients with acute ischemic stroke (AIS) who underwent endovascular treatment (EVT). Methods: A total of 97 AIS patients who achieved complete or near-complete recanalization after EVT were included in our study. Clinical, angiographic, and laboratory data were analyzed retrospectively. Using the modified Rankin Scale (mRS) at 90 days after the intervention, the patients were divided into two groups, the futile recanalization group (mRS =3) and the favorable recanalization group (mRS =2). The receiver-operating characteristics (ROC) curve was used to determine the cut-off value of the CHA2DS2-VASc score for predicting futile recanalization. Multivariate stepwise logistic regression analysis analyzed the association between the CHA2DS2-VASc score and futile recanalization risk after EVT. Results: The CHA2DS2-VASc score was significantly higher in patients with futile recanalization compared to patients with favorable recanalization [4 (3-6) vs. 3 (1-4), p=0.002]. A ROC curve analysis revealed that the cut-off value of CHA2DS2-VASc score for predicting futile recanalization was >3, with sensitivity and specificity of 65% and 72%, respectively (Area under curve (AUC), 0.697; 95% Confidence interval (CI):0.580-0.814). In multivariate analysis;the CHA2DS2-VASc score (Odds ratio (OR)=1.637, 95% CI:1.181-2.334, p=0.004) and baseline National Institutes of Health Stroke Scale score (OR=1.217, 95% CI:0.985-1.503, p=0.039) were found independent predictors for futile recanalization after EVT. Conclusion: The CHA2DS2-VASc score can be used as a simple and effective tool to predict futile recanalization in patients with AIS. [ABSTRACT FROM AUTHOR]