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18 results on '"Ueno, Eiichi"'

3. Development of the salt-reduction and efficacy-maintenance program in Indonesia

Author

Irwan, Andi Masyitha, Kato, Mayumi, Kitaoka, Kazuyo, Ueno, Eiichi, Tsujiguchi, Hiromasa, and Shogenji, Miho

Subjects
Randomized controlled trial, Hypertension, Salt, Patient education, Older people, Self-care, Self-efficacy, Primary health
Abstract

We conducted a randomized, controlled trial to examine the effects of a salt-reduction and efficacy-maintenance program on the improvement and maintenance of self-care and self-efficacy in reducing the salt intake of older people with high blood pressure. A total of 51 participants with hypertension/prehypertension in Indonesia were randomly assigned to a control group or one of two intervention groups: salt-reduction training or salt-reduction and efficacy-maintenance. The salt-reduction and efficacy-maintenance group received educational training and a maintenance meeting; the participants' knowledge, attitudes, self-care practices, and self-efficacy significantly improved after training and were maintained after the maintenance meeting. Participants in the salt-reduction training group showed significant effects for the same variables; however, their food salt concentrations rebounded after the maintenance meeting. No significant improvement was found in the control group. The salt-reduction and efficacy-maintenance group participants reported positive effects of salt reduction and different practices based on who prepared their meals. The salt-reduction and efficacy-maintenance group program was effective in improving and maintaining knowledge, attitudes, and self-efficacy of salt-reduction practices and could be applied with community-dwelling older people with high blood pressure. © 2016 John Wiley & Sons Australia, Ltd., Embargor Period 12 months

Published
2016

6. Development of the salt-reduction and efficacy-maintenance program in Indonesia

Author

Irwan, Andi Masyitha, Kato, Mayumi, Kitaoka, Kazuyo, Ueno, Eiichi, Tsujiguchi, Hiromasa, Shogenji, Miho, Irwan, Andi Masyitha, Kato, Mayumi, Kitaoka, Kazuyo, Ueno, Eiichi, Tsujiguchi, Hiromasa, and Shogenji, Miho

Abstract

We conducted a randomized, controlled trial to examine the effects of a salt-reduction and efficacy-maintenance program on the improvement and maintenance of self-care and self-efficacy in reducing the salt intake of older people with high blood pressure. A total of 51 participants with hypertension/prehypertension in Indonesia were randomly assigned to a control group or one of two intervention groups: salt-reduction training or salt-reduction and efficacy-maintenance. The salt-reduction and efficacy-maintenance group received educational training and a maintenance meeting; the participants' knowledge, attitudes, self-care practices, and self-efficacy significantly improved after training and were maintained after the maintenance meeting. Participants in the salt-reduction training group showed significant effects for the same variables; however, their food salt concentrations rebounded after the maintenance meeting. No significant improvement was found in the control group. The salt-reduction and efficacy-maintenance group participants reported positive effects of salt reduction and different practices based on who prepared their meals. The salt-reduction and efficacy-maintenance group program was effective in improving and maintaining knowledge, attitudes, and self-efficacy of salt-reduction practices and could be applied with community-dwelling older people with high blood pressure. © 2016 John Wiley & Sons Australia, Ltd., Embargor Period 12 months

Published
2017

7. Potential Role of Gab1 and PLC [Gamma] in Osmotic Shock-induced Glucose Uptake

Author

UENO, EIICHI, IWATA, MINORU, KAWAHARA, JUNKO, UNO, TATSUHITO, and HARUTA, TETSURO

Subjects
Diabetes -- Research, Health
Abstract

In 3T3-L 1 adipocytes, osmotic shock induces GLUT4 translocation independently of PI 3-kinase, and tyrosine phosphorylation has been implicated in the mechanism. Tyrosine phosphorylation of several molecular weight species including [...]

Published
1999

8. The Mechanism of Insulin-Induced Clonal Expansion in Adipocyte Differentiation--the Importance of PI3 Kinae-Rapamycin-Sensitive Pathway

Author

USUI, ISAO, HARUTA, TETSURO, UNO, TATSUHITO, TAKANO, ATSUKO, UENO, EIICHI, and KOBAYASHI, MASASHI

Subjects
Diabetes -- Research, Health
Abstract

A transient increase of DNA synthesis in the early phase of adipocyte differentiation, called clonal expansion, is believed to be an essential process for adipocyte differentiation. In this study, we [...]

Published
1999

9. Degradation of Phosphorylated IRS-1 by Proteasome After Long-term Insulin Stimulation

Author

JUNKO, KAWAHARA, MINORU, IWATA, TATSUHITO, UNO, EIICHI, UENO, MASASHI, KOBAYASHI KAWAHARA, JUNKO, IWATA, MINORU, UNO, TATSUHITO, UENO, EIICHI, and KOBAYASHI, MASASHI

Subjects
Diabetes -- Research, Health
Abstract

Prolonged insulin treatment decreases the amount of IRS-l, and thereby insulin desensitization occurs. To clarify the mechanism and the functional consequences of IRS-1 degradation after prolonged treatment with insulin, we [...]

Published
1999

12. Relative Involvement of Shc Tyrosine 239/240 and Tyrosine 317 on Insulin Induced Mitogenic Signaling in Rat1 Fibroblasts Expressing Insulin Receptors

Author

Ishihara, Hajime, primary, Sasaoka, Toshiyasu, additional, Wada, Tsutomu, additional, Ishiki, Manabu, additional, Haruta, Tetsuro, additional, Usui, Isao, additional, Iwata, Minoru, additional, Takano, Atsuko, additional, Uno, Tatsuhito, additional, Ueno, Eiichi, additional, and Kobayashi, Masashi, additional

Published
1998
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16. Pioglitazone ameliorates tumor necrosis factor-alpha-induced insulin resistance by a mechanism independent of adipogenic activity of peroxisome proliferator--activated receptor-gamma.

Author

Iwata, Minoru, Haruta, Tetsuro, Usui, Isao, Takata, Yasumitsu, Takano, Atsuko, Uno, Tatsuhito, Kawahara, Junko, Ueno, Eiichi, Sasaoka, Toshiyasu, Ishibashi, Osamu, Kobayashi, Masashi, Iwata, M, Haruta, T, Usui, I, Takata, Y, Takano, A, Uno, T, Kawahara, J, Ueno, E, and Sasaoka, T

Subjects
TUMOR necrosis factors, INSULIN resistance, FAT cells
Abstract

Tumor necrosis factor (TNF)-alpha is one of the candidate mediators of insulin resistance associated with obesity, a major risk factor for the development of type 2 diabetes. The insulin resistance induced by TNF-alpha is antagonized by thiazolidinediones (TZDs), a new class of insulin-sensitizing drugs. The aim of the current study was to dissect the mechanism whereby pioglitazone, one of the TZDs, ameliorates TNF-alpha-induced insulin resistance in 3T3-L1 adipocytes. Pioglitazone restored insulin-stimulated 2-deoxyglucose (DOG) uptake, which was reduced by TNF-alpha, with concomitant restorations in tyrosine phosphorylation and protein levels of insulin receptor (IR) and insulin receptor substrate (IRS)-1, as well as association of the p85 regulatory subunit of phosphatidylinositol (PI) 3-kinase with IRS-1 and PI 3-kinase activity. Adenovirus-mediated gene transfer of either wild-type human peroxisome proliferator-activated receptor (PPAR)-gamma2 or a mutant carrying a replacement at the consensus mitogen-activated protein kinase phosphorylation site (hPPAR-gamma2-S112A) promoted adipogenesis of 3T3-L1 fibroblasts and restored TNF-alpha-induced decrease of triglyceride in adipocytes as effectively as pioglitazone. Overexpression of the PPAR-gamma proteins in TNF-alpha-treated adipocytes restored protein levels of IR/IRS-1, but did not improve insulin-stimulated tyrosine phosphorylation of IR/IRS-1 or insulin-stimulated 2-DOG uptake. These results indicate that the ability of pioglitazone to restore insulin-stimulated tyrosine phosphorylation of IR/IRS-1, which is necessary for amelioration of TNF-alpha-induced insulin resistance, may be independent of the adipogenic activity of PPAR-gamma that regulates protein levels of IR/IRS-1. [ABSTRACT FROM AUTHOR]

Published
2001
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17. A case of cardiac resynchronization therapy in a patient with coronary sinus ostial atresia and persistent left superior vena cava.

Author

Fujibayashi K, Saeki Y, Sawaguchi J, Yasuda Y, Ueno E, Takano S, Fujioka N, Kawai Y, and Kajinami K

Abstract

Coronary sinus ostial atresia is rare and usually not clinically relevant, but it should be noted in cases of cardiac resynchronization therapy. A rare case of successful left ventricular lead implantation for cardiac resynchronization therapy via the left superior vena cava in a patient with coronary sinus ostial atresia is reported. The persistent left superior vena cava associated with these cases tends to be smaller than usual in its diameter and difficult to identify, since the direction of venous drainage is reversed. Therefore, in the present case, it was useful to use a small-diameter, soft inner catheter as a guiding catheter to perform selective imaging and avoid vascular injury. In addition, it appeared to be important to plan the surgical strategy using prior imaging information, since it would be difficult to obtain the backup needed for lead insertion., 〈: Learning objective: Cardiac resynchronization therapy via the left superior vena cava with coronary sinus ostial atresia is generally possible without problems if prior imaging information is available, such as three-dimensional computed tomography and the venous phase of coronary angiography. It is important to determine whether there is a persistent left superior vena cava before the procedure. Thromboprophylaxis remains controversial in this situation.〉., (© 2019 Japanese College of Cardiology. Published by Elsevier Ltd.)

Published
2019
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18. [Regional Comparison on Recognition of Tasks for a Home Care System-Analysis of Medical Plans of 47 Prefectures by Text Mining and GIS].

Author

Itatani T, Horiike R, Taira K, and Ueno E

Subjects
Data Mining, Humans, Japan, Research Report, Geographic Information Systems, Home Care Services
Abstract

A medical plan reflectsthe current state of a region. The purpose of thisres earch isto analyze medical plansby text mining and examine geographical features using a geographic information system. From the medical plans of 47 prefectures, nationwide, 6 regional divisions', and four age groups' text fileswere prepared. Further, wordswere extracted and subsequently, their relevance wasanalyzed. Additionally, we examined the geographical featuresus ing a color-dividing Japanese map by the word appearance rate of"Mitori"(end-of-life care), which is an important task. In the aggregate nationwide text files, 214,716 words were extracted. The top frequent words were medical care, home, support, nursing care, visit, medical treatment, and cooperation. In the co-occurrence network, medical care- home- nursing care- cooperation were connected with organization- construction. There was a link between human resources- training in Kanto and Kinki."Mitori"frequently occurred in areaswith a high aging rate, and there wasa human resources- training- securing connection in areas with a low aging rate. The frequency of"Mitori"was high in western Japan. The results suggested that collaboration between medical care and nursing care is emphasized in medical planning. Further,"Mitori"was emphasized in western Japan or areas with a high aging rate while human resourcesdevelopment wasemphas ized in areaswith a low aging rate.

Published
2019

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