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131 results on '"Uchida, Katsuya"'

2. Dual action of serotonin on local excitatory and inhibitory neural circuits regulating the corticotropin‐releasing factor neurons in the paraventricular nucleus of the hypothalamus

Author

Sato, Takayuki, primary, Sugaya, Takuma, additional, Talukder, Ashraf Hossain, additional, Tsushima, Yuki, additional, Sasaki, Shotaro, additional, Uchida, Katsuya, additional, Sato, Tatsuya, additional, Ikoma, Yoko, additional, Sakimura, Kenji, additional, Fukuda, Atsuo, additional, Matsui, Ko, additional, and Itoi, Keiichi, additional

Published
2023
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3. Establish Security Psychology – How to Educate and Training for End Users

Author

Uchida, Katsuya, Diniz Junqueira Barbosa, Simone, Series editor, Chen, Phoebe, Series editor, Du, Xiaoyong, Series editor, Filipe, Joaquim, Series editor, Kara, Orhun, Series editor, Kotenko, Igor, Series editor, Liu, Ting, Series editor, Sivalingam, Krishna M., Series editor, Washio, Takashi, Series editor, and Stephanidis, Constantine, editor

Published
2017
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4. Vasopressin Expressed in Hypothalamic CRF Neurons Causes Impaired Water Diuresis in Secondary Adrenal Insufficiency

Author

Yamagata, Satoshi, primary, Talukder, Ashraf H, additional, Murasawa, Shingo, additional, Niioka, Kanako, additional, Kumagai, Naoya, additional, Takagi, Mao, additional, Kawamura, Meiko, additional, Natsume, Rie, additional, Abe, Manabu, additional, Uchida, Katsuya, additional, Sato, Tatsuya, additional, Kurose, Akira, additional, Kageyama, Kazunori, additional, Daimon, Makoto, additional, Sakimura, Kenji, additional, and Itoi, Keiichi, additional

Published
2023
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5. A Psychological Approach to Information Security : Some Ideas for Establishing Information Security Psychology

Author

Uchida, Katsuya, Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Weikum, Gerhard, Series editor, and Kurosu, Masaaki, editor

Published
2015
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9. Energy fluctuations in recorder pipes during transient sound attacks and steady state sound

Author

Hirofumi Onitsuka, Uchida Katsuya, Tetsuro Shoji, and Akira Miki

Subjects
Physics, geography, Steady state (electronics), geography.geographical_feature_category, Mechanics, Transient (oscillation), Energy (signal processing), Sound (geography)
Abstract

The evaluation of temporal and spatial fluctuations of energy using compressible fluid analysis is proposed as an effective method to clarify the fundamental mechanism of the self-sustained oscilla-tions in a actual recorder. The main factors of the self-sustained oscillations are investigated in more detail by evaluating not only the steady state of the sound where the flow field and the sound field are completely coupled, but also the characteristics at the attack transient of the sound before the coupling is established. By analyzing the large energy fluctuations that occur just below the edge of the labium in the attack transient, it was shown that this phenomenon may be one of the main causes of the self-sustained oscillations. And the characteristics of the energy fluctuations and sound power generation during the steady state of the sound are discussed. It was also focused on the energy variations in another region that is near the exit of the windway.

Published
2021

23. Distribution of corticotropin-releasing factor neurons in the mouse brain: a study using corticotropin-releasing factor-modified yellow fluorescent protein knock-in mouse

Author

Kono, Junko, primary, Konno, Kohtarou, additional, Talukder, Ashraf Hossain, additional, Fuse, Toshimitsu, additional, Abe, Manabu, additional, Uchida, Katsuya, additional, Horio, Shuhei, additional, Sakimura, Kenji, additional, Watanabe, Masahiko, additional, and Itoi, Keiichi, additional

Published
2016
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24. Genome-Wide Analysis of Glucocorticoid-Responsive Transcripts in the Hypothalamic Paraventricular Region of Male Rats.

Author

Itoi, Keiichi, Motoike, Ikuko, Liu, Ying, Clokie, Sam, Iwasaki, Yasumasa, Uchida, Katsuya, Sato, Tatsuya, and Aguilera, Greti

Abstract

Glucocorticoids (GCs) are essential for stress adaptation, acting centrally and in the periphery. Corticotropin-releasing factor (CRF), a major regulator of adrenal GC synthesis, is produced in the paraventricular nucleus of the hypothalamus (PVH), which contains multiple neuroendocrine and preautonomic neurons. GCs may be involved in diverse regulatory mechanisms in the PVH, but the target genes of GCs are largely unexplored except for the CRF gene (Crh), a well-known target for GC negative feedback. Using a genome-wide RNA-sequencing analysis, we identified transcripts that changed in response to either high-dose corticosterone (Cort) exposure for 12 days (12-day high Cort), corticoid deprivation for 7 days (7-day ADX), or acute Cort administration. Among others, canonical GC target genes were upregulated prominently by 12-day high Cort. Crh was upregulated or downregulated most prominently by either 7-day ADX or 12-day high Cort, emphasizing the recognized feedback effects of GC on the hypothalamic-pituitary-adrenal (HPA) axis. Concomitant changes in vasopressin and apelin receptor gene expression are likely to contribute to HPA repression. In keeping with the pleotropic cellular actions of GCs, 7-day ADX downregulated numerous genes of a broad functional spectrum. The transcriptome response signature differed markedly between acute Cort injection and 12-day high Cort. Remarkably, six immediate early genes were upregulated 1 hour after Cort injection, which was confirmed by quantitative reverse transcription PCR and semiquantitative in situ hybridization. This study may provide a useful database for studying the regulatory mechanisms of GC-dependent gene expression and repression in the PVH.

Published
2019
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29. Selective ablation of locus coeruleus noradrenergic neurons expressing human interleukin-2 receptor α-subunit in transgenic mice by a recombinant immunotoxin: Exploring noradrenergic influence upon anxiety-like and depression-like behaviors

Author

Itoi, Keiichi, primary, Sugimoto, Naoya, additional, Suzuki, Saya, additional, Sawada, Keisuke, additional, Das, Gopal, additional, Uchida, Katsuya, additional, Fuse, Toshimitsu, additional, Ohara, Shinji, additional, and Kobayashi, Kazuto, additional

Published
2011
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31. Identification of novel transcription factors for catecholamine gene expression based upon the comprehensive analyses of transcripts in fetal pontine noradrenergic neurons using trasngenic mice expressing green fluorescent protein under the promoter of tyrosine hydroxylase

Author

Yokohashi, Haruka, primary, Uchida, Katsuya, additional, Fuse, Toshimitsu, additional, Iwasaki, Yasumasa, additional, Kinoshita, Kengo, additional, Okazaki, Akira, additional, Das, Gopal, additional, Sawada, Keisuke, additional, Tanaka, Chiaki, additional, Tomita, Hiroaki, additional, Ohara, Shinji, additional, Kobayashi, Kazuto, additional, and Itoi, Keiichi, additional

Published
2011
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46. Targeting of Locus Ceruleus Noradrenergic Neurons Expressing Human Interleukin-2 Receptor α-Subunit in Transgenic Mice by a Recombinant Immunotoxin anti-Tac(Fv)-PE38: A Study for Exploring Noradrenergic Influence upon Anxiety-Like and Depression-Like Behaviors

Author

Itoi, Keiichi, Sugimoto, Naoya, Suzuki, Saya, Sawada, Keisuke, Das, Gopal, Uchida, Katsuya, Fuse, Toshimitsu, Ohara, Shinji, and Kobayashi, Kazuto

Subjects
NORADRENERGIC neurons, LOCUS (Genetics), INTERLEUKIN-2, TRANSGENIC mice, ANTIBODY-toxin conjugates, CELL receptors, PROMOTERS (Genetics)
Abstract

The noradrenergic (NA) neurons in the locus ceruleus (LC) were ablated with a high degree of selectivity by immunotoxin-mediated neuronal targeting. Transgenic mice were used in which the human interleukin-2 receptor-α subunit (hIL-2Rα; Tac) is expressed under the promoter of dopamine β-hydroxylase. The recombinant immunotoxin, which is composed of the Fv fragment of an anti-hIL-2Rα monoclonal antibody fused to a truncated form of Pseudomonas exotoxin [anti-Tac(Fv)-PE38], was injected bilaterally into the LC of the mouse. As a result, the LC-NA neurons disappeared almost completely, and tissue noradrenaline was depleted in brain regions that receive NA inputs from the LC. The decrement of tissue noradrenaline content was more profound compared with that in mice treated with N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4), a neurotoxin capable of ablating axons originating from the LC-NA neurons. Mice treated with either the immunotoxin or DSP-4 presented increased anxiety-like behaviors; in contrast, only the immunotoxintreated mice, and not the DSP-4-treated mice, showed increased depression-like behavior. The immunotoxin-mediated neuronal targetingmayprovide a means for further unraveling the links between the LC and pathological manifestations of neurological disorders. [ABSTRACT FROM AUTHOR]

Published
2011
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47. Basic properties and annual changes of follicle-stimulating hormone receptors in the testis of horseshoe bats, <TOGGLE>Rhinolophus ferrumequinum</TOGGLE>

Author

Hayashi, Toshiyuki, Uchida, Katsuya, and Kawamoto, Keiichi

Abstract

The unique reproductive patterns, delayed fertilization in females, and asynchrony between spermatogenesis and mating behavior in males are well documented in bats living in temperate latitudes. The present study was undertaken to examine follicle-stimulating hormone (FSH) receptors in the testis of bats, Rhinolophus ferrumequinum, during the annual reproductive cycle. Male bats were captured at natural roosting sites and testicular preparations were subjected to a radioligand binding assay for FSH receptors. The weight of paired testes increased considerably in the spermatogenic period and decreased from the mating to hibernation periods. Meiotic division in the testis was observed in the spermatogenic period but not the mating period. Serum testosterone concentrations increased in the spermatogenic period and rapidly decreased in the mating period. The binding of FSH was specific for mammalian FSHs and detected primarily in the testis. Scatchard plot analyses of the binding of FSH to bat testicular preparations showed straight lines, suggesting the presence of a single class of binding sites. The affinities (equilibrium association constant) of FSH receptors were consistent throughout the annual reproductive cycle. The specific binding per unit weight of testis and total binding in the paired testes were highest in the mating period and in the spermatogenic period, respectively, among reproductive periods. The accumulation of cyclic adenosine 3', 5'-monophosphate to FSH stimulation was higher in the spermatogenic period than in the hibernation period. These findings suggest that testicular function of bats is associated with seasonal changes in the number of binding sites, while the number per target cell and the activation of adenylate cyclase led by FSH-receptor complex considerably decreases in the hibernation period. J. Exp. Zool. 292:304–313, 2002. © 2002 Wiley-Liss, Inc.

Published
2002
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49. Temperature distribution in Li2O pellets under neutron irradiation

Author

Nasu, Shoichi, primary, Tanifuji, Takaaki, additional, Uchida, Katsuya, additional, Noda, Kenji, additional, Kurasawa, Toshimasa, additional, Takahashi, Tadashi, additional, Isshiki, Masahiko, additional, Miyauchi, Takejiro, additional, Tanuma, Kohji, additional, and Sasajima, Fumio, additional

Published
1980
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