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13 results on '"Uchi, Sho-Hei"'

3. Efficacy of ripasudil in reducing intraocular pressure and medication score for ocular hypertension with inflammation and corticosteroid

Author

Yanai, Ryoji, Uchi, Sho-Hei, Kobayashi, Masaaki, Nagai, Tomohiko, Teranishi, Shinichiro, Wakuta, Makiko, and Kimura, Kazuhiro

Subjects
Clinical Research
Abstract

AIM: To investigate the efficacy of ripasudil, a Rho kinase inhibitor, in reducing intraocular pressure (IOP) and medication scores of anti-glaucoma drugs in patients with ocular hypertension with inflammation and corticosteroid. METHODS: The study included 11 patients diagnosed with ocular hypertension with inflammation and corticosteroid, all of whom were prescribed ripasudil eye drops and followed up for at least 2y after the initiation of treatment. IOP was measured using a non-contact tonometer before enrollment and at each follow-up visit. The medication score of glaucoma eye drops was calculated for each patient. RESULTS: The mean IOP (26.4±2.9 mm Hg before treatment) significantly decreased after ripasudil therapy (13.7±3.3 mm Hg at 3mo) and remained stable in the low-teens during the 2-year follow-up period (P

Published
2023

5. Correction: Dendritic cells mediate the anti-inflammatory action of omega-3 long-chain polyunsaturated fatty acids in experimental autoimmune uveitis

Author

Uchi, Sho-Hei, primary, Yanai, Ryoji, additional, Kobayashi, Masaaki, additional, Hatano, Makoto, additional, Kobayashi, Yuka, additional, Yamashiro, Chiemi, additional, Nagai, Tomohiko, additional, Tokuda, Kazuhiro, additional, Connor, Kip M., additional, Sonoda, Koh-Hei, additional, and Kimura, Kazuhiro, additional

Published
2020
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7. Dendritic cells mediate the anti-inflammatory action of omega-3 long-chain polyunsaturated fatty acids in experimental autoimmune uveitis

Author

Uchi, Sho-Hei, primary, Yanai, Ryoji, additional, Kobayashi, Masaaki, additional, Hatano, Makoto, additional, Kobayashi, Yuka, additional, Yamashiro, Chiemi, additional, Nagai, Tomohiko, additional, Tokuda, Kazuo, additional, Connor, Kip M., additional, Sonoda, Koh-Hei, additional, and Kimura, Kazuhiro, additional

Published
2019
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12. Efficacy of ripasudil in reducing intraocular pressure and medication score for ocular hypertension with inflammation and corticosteroid.

Author

Yanai R, Uchi SH, Kobayashi M, Nagai T, Teranishi S, Wakuta M, and Kimura K

Abstract

Aim: To investigate the efficacy of ripasudil, a Rho kinase inhibitor, in reducing intraocular pressure (IOP) and medication scores of anti-glaucoma drugs in patients with ocular hypertension with inflammation and corticosteroid., Methods: The study included 11 patients diagnosed with ocular hypertension with inflammation and corticosteroid, all of whom were prescribed ripasudil eye drops and followed up for at least 2y after the initiation of treatment. IOP was measured using a non-contact tonometer before enrollment and at each follow-up visit. The medication score of glaucoma eye drops was calculated for each patient., Results: The mean IOP (26.4±2.9 mm Hg before treatment) significantly decreased after ripasudil therapy (13.7±3.3 mm Hg at 3mo) and remained stable in the low-teens during the 2-year follow-up period ( P <0.0001). A significant decrease in the medication score was observed at 12mo or later after the initiation of ripasudil therapy ( P <0.05). Both baseline medication scores and glaucomatous optic disc change rates were significantly higher in the five eyes that required glaucoma surgery during the 2-year observation period than the 10 eyes that did not require surgery., Conclusion: Our results demonstrate the efficacy of ripasudil, in reducing IOP and the medication score over a 2-year treatment period in patients with ocular hypertension with inflammation and corticosteroid. Our findings also suggest that ripasudil could reduce the IOP in uveitic glaucoma patients with both lower baseline medication score and lower glaucomatous optic disc change rate., (International Journal of Ophthalmology Press.)

Published
2023
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13. A CASE OF CAT SCRATCH DISEASE DIAGNOSED BY INDIRECT FLUORESCENT ANTIBODY ASSAY OF IgM SPECIFIC FOR A JAPANESE STRAIN OF Bartonella henselae.

Author

Uchi SH, Yanai R, Tsuneoka H, Otsuyama KI, Sonoda KH, and Kimura K

Subjects
Bartonella henselae immunology, Female, Fluorescent Antibody Technique, Humans, Immunoglobulin M isolation & purification, Japan, Pregnancy, Pregnancy Complications, Infectious diagnosis, Retinitis etiology, Young Adult, Cat-Scratch Disease complications, Cat-Scratch Disease diagnosis
Abstract

Purpose: To report a case of cat scratch disease-associated retinitis diagnosed with an indirect fluorescent antibody (IFA) assay for immunoglobulin M (IgM) specific for a strain (YH-01) of Bartonella henselae recently identified in Japan., Methods: Case report of a 24-year-old pregnant woman presented with general fever, fatigue, as well as blurred vision, and a central visual field deficiency in her right eye and was suspected as cat scratch disease because she had started to feed a feral dog a month ago., Results: The patient's serum tested negative, however, with an IFA assay for IgG or IgM specific for the Houston-1, common strain of B. henselae. Further testing with an IFA assay for IgM specific for the YH-01 strain yielded a positive result. On the basis of the clinical findings and the IFA results, we were thus able to make a definitive diagnosis of cat scratch disease., Conclusion: An IFA assay based on the YH-01 or combination of both YH-01 and Houston-1 strains of B. henselae may show increased sensitivity for the diagnosis of cat scratch disease in Japan., (Copyright © 2019 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the Opthalmic Communications Society, Inc.)

Published
2021
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