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1. Parkin deficiency exacerbates particulate matter-induced injury by enhancing airway epithelial necroptosis.

2. Tripartite motif 25 inhibits protein aggregate degradation during PRRSV infection by suppressing p62-mediated autophagy.

3. Cyclophilin A facilitates HIV-1 integration.

4. GPRC5A promotes lung colonization of esophageal squamous cell carcinoma.

5. Germline pathogenic variants in RNF43 in patients with and without serrated polyposis syndrome.

6. Structural basis for C-degron selectivity across KLHDCX family E3 ubiquitin ligases.

7. Parkin paves the path to antitumor immunity: Expanding Parkin's role as a tumor suppressor.

8. HSP70 promotes amino acid-dependent mTORC1 signaling by mediating CHIP-induced NPRL2 ubiquitination and degradation.

9. MARCH8 Mediates K27-Linked Polyubiquitination of IL-7 Receptor α to Negatively Regulate IL-7-Triggered T Cell Homeostasis.

10. Selenomethionine supplementation mitigates fluoride-induced liver apoptosis and inflammatory reactions by blocking Parkin-mediated mitophagy in mice.

11. Saturation mutagenesis-reinforced functional assays for disease-related genes.

12. XAF1 antagonizes TRIM28 activity through the assembly of a ZNF313-mediated destruction complex to suppress tumor malignancy.

13. Enhanced CFTR modulator efficacy in ΔF508 CFTR mouse organoids by ablation of RFFL ubiquitin ligase.

14. The ubiquitin-proteasome system degrades fatty acid synthase under nitrogen starvation when autophagy is dysfunctional in Saccharomyces cerevisiae.

15. Synergistic involvement of the NZF domains of the LUBAC accessory subunits HOIL-1L and SHARPIN in the regulation of LUBAC function.

16. PI3K p85α/HIF-1α accelerates the development of pulmonary arterial hypertension by regulating fatty acid uptake and mitophagy.

17. Deletion of MAPL ameliorates septic cardiomyopathy by mitigating mitochondrial dysfunction.

18. The E3 ubiquitin ligase RNF220 maintains hindbrain Hox expression patterns through regulation of WDR5 stability.

19. Structural mechanisms of SLF1 interactions with Histone H4 and RAD18 at the stalled replication fork.

20. [Genetic analysis of a pedigree affected with Intellectual disability due to variants of two different genes].

21. TRIM47 drives gastric cancer cell proliferation and invasion by regulating CYLD protein stability.

22. Endosomes serve as signaling platforms for RIG-I ubiquitination and activation.

23. Pharmacologic or genetic interference with atrogene signaling protects against glucocorticoid-induced musculoskeletal and cardiac disease.

24. Purkinje cell-specific deficiency in SEL1L-hrd1 endoplasmic reticulum-associated degradation causes progressive cerebellar ataxia in mice.

25. The rs6576457 G > A variant in the MKRN3 gene promoter significantly increases the risk of central precocious puberty and lung cancer in Hubei Chinese population.

26. UBR7 E3 Ligase Suppresses Interferon-β Mediated Immune Signaling by Targeting Sp110 in Hepatitis B Virus-Induced Hepatocellular Carcinoma.

27. RNF13 protects neurons against ischemia-reperfusion injury via stabilizing p62-mediated Nrf2/HO-1 signaling pathway.

28. ZIP7 contributes to the pathogenesis of diabetic cardiomyopathy by suppressing mitophagy in mouse hearts.

29. Mechanism of phospho-Ubls' specificity and conformational changes that regulate Parkin activity.

30. AMFR-mediated Flavivirus NS2A ubiquitination subverts ER-phagy to augment viral pathogenicity.

31. RNF19A inhibits bladder cancer progression by regulating ILK ubiquitination and inactivating the AKT/mTOR signalling pathway.

32. Evidence for a hydrogen sulfide-sensing E3 ligase in yeast.

33. AAV vector-derived elements integrate into Cas9-generated double-strand breaks and disrupt gene transcription.

34. STUB1 suppresses paclitaxel resistance in ovarian cancer through mediating HOXB3 ubiquitination to inhibit PARK7 expression.

35. Artificial selection of two antagonistic E3 ubiquitin ligases finetunes soybean photoperiod adaptation and grain yield.

36. Protection of Ndrg2 deficiency on renal ischemia-reperfusion injury via activating PINK1/Parkin-mediated mitophagy.

37. Exposure to BaA inhibits trophoblast cell invasion and induces miscarriage by regulating the DEC1/ARHGAP5 axis and promoting ubiquitination-mediated degradation of MMP2.

38. RNF213 in moyamoya disease: Genotype-phenotype association and the underlying mechanism.

39. PINK1/Parkin-Mediated Mitophagy Ameliorates Mitochondrial Dysfunction in Lacrimal Gland Acinar Cells During Aging.

40. CXCL12/CXCR4 pathway as a novel therapeutic target for RNF213-associated pulmonary arterial hypertension.

41. Lactylation stabilizes TFEB to elevate autophagy and lysosomal activity.

42. ACSL1 improves pulmonary fibrosis by reducing mitochondrial damage and activating PINK1/Parkin mediated mitophagy.

43. Black carp RNF135 enhances RIG-I-mediated antiviral signaling by facilitating its oligomerization.

44. UBE3A: Bridging the gap between neurodevelopment, neural function, and neurodegenerative woes.

45. CARD9 protein SUMOylation regulates HOXB5 nuclear translocation and Parkin-mediated mitophagy in myocardial I/R injury.

46. Inhibition of mitochondrial OMA1 ameliorates osteosarcoma tumorigenesis.

47. Genetic Variations in TP53, RB1 , and PTEN in a Selected Sample of Slovak Patients With Metastatic Castration-resistant Prostate Cancer.

48. STAT6 promotes innate immunity against BEFV and VSV by inhibiting STUB1 and NIX-mediated MAVS degradation.

49. Distinct Regions within SAP25 Recruit O-Linked Glycosylation, DNA Demethylation, and Ubiquitin Ligase and Hydrolase Activities to the Sin3/HDAC Complex.

50. The PINK1/Parkin signaling pathway-mediated mitophagy: a forgotten protagonist in myocardial ischemia/reperfusion injury.

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