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365 results on '"U. Valente"'

1. Optimization of Electromagnetic Design After Winding Tests for the Nb3Sn Cos-Theta Dipole Model for FCC-hh

Author

R. U. Valente, A. Ballarino, A. Bersani, M. Bracco, S. Burioli, B. Caiffi, S. Coelli, E. De Matteis, S. Farinon, A. Gagno, F. Levi, S. Mariotto, R. Musenich, A. Palmisano, A. Pampaloni, D. Perini, M. Prioli, N. Sala, M. Sorbi, S. Sorti, M. Statera, and G. Vernassa

Subjects
Superconducting magnets, Settore FIS/01 - Fisica Sperimentale, Nb3Sn, FCC, accelerator dipoles, finite element analysis, Electrical and Electronic Engineering, Condensed Matter Physics, Electronic, Optical and Magnetic Materials
Published
2023

2. Experience on Series Production of the HL-LHC Superferric High Order Corrector Magnets

Author

M. Statera, M. Prioli, F. Broggi, E. De Matteis, L. Imeri, A. Leone, S. Mariotto, A. Paccalini, A. Pasini, D. Pedrini, L. Rossi, M. Sorbi, S. Sorti, M. Todero, R. U. Valente, E. Gautheron, E. Todesco, M. Campaniello, M. Canetti, F. Gangini, P. Manini, C. Santini, and A. Zanichelli

Subjects
Electrical and Electronic Engineering, Condensed Matter Physics, Electronic, Optical and Magnetic Materials
Published
2023

5. Design of a 4 T Curved Demonstrator Magnet for a Superconducting Ion Gantry

Author

M. Prioli, E. De Matteis, S. Farinon, E. Felcini, A. Gagno, S. Mariotto, R. Musenich, M. Pullia, L. Rossi, M. Sorbi, S. Sorti, M. Statera, and R. U. Valente

Subjects
Magnetic domains, Ions, Accelerator magnets, Settore FIS/01 - Fisica Sperimentale, Coils, Superconducting magnets, Cooling, Magnetic separation, Three-dimensional displays, gantry, hadrontherapy, superconducting magnets, Condensed Matter Physics, Electronic, Optical and Magnetic Materials, Electrical and Electronic Engineering
Published
2023

6. FCC Physics Opportunities

Author

A. Abada, M. Abbrescia, S. S. AbdusSalam, I. Abdyukhanov, J. Abelleira Fernandez, A. Abramov, M. Aburaia, A. O. Acar, P. R. Adzic, P. Agrawal, J. A. Aguilar-Saavedra, J. J. Aguilera-Verdugo, M. Aiba, I. Aichinger, G. Aielli, A. Akay, A. Akhundov, H. Aksakal, J. L. Albacete, S. Albergo, A. Alekou, M. Aleksa, R. Aleksan, R. M. Alemany Fernandez, Y. Alexahin, R. G. Alía, S. Alioli, N. Alipour Tehrani, B. C. Allanach, P. P. Allport, M. Altınlı, W. Altmannshofer, G. Ambrosio, D. Amorim, O. Amstutz, L. Anderlini, A. Andreazza, M. Andreini, A. Andriatis, C. Andris, A. Andronic, M. Angelucci, F. Antinori, S. A. Antipov, M. Antonelli, M. Antonello, P. Antonioli, S. Antusch, F. Anulli, L. Apolinário, G. Apollinari, A. Apollonio, D. Appelö, R. B. Appleby, Ara. Apyan, Arm. Apyan, A. Arbey, A. Arbuzov, G. Arduini, V. Arı, S. Arias, N. Armesto, R. Arnaldi, S. A. Arsenyev, M. Arzeo, S. Asai, E. Aslanides, R. W. Aßmann, D. Astapovych, M. Atanasov, S. Atieh, D. Attié, B. Auchmann, A. Audurier, S. Aull, S. Aumon, S. Aune, F. Avino, G. Avrillaud, G. Aydın, A. Azatov, G. Azuelos, P. Azzi, O. Azzolini, P. Azzurri, N. Bacchetta, E. Bacchiocchi, H. Bachacou, Y. W. Baek, V. Baglin, Y. Bai, S. Baird, M. J. Baker, M. J. Baldwin, A. H. Ball, A. Ballarino, S. Banerjee, D. P. Barber, D. Barducci, P. Barjhoux, D. Barna, G. G. Barnaföldi, M. J. Barnes, A. Barr, J. Barranco García, J. Barreiro Guimarães da Costa, W. Bartmann, V. Baryshevsky, E. Barzi, S. A. Bass, A. Bastianin, B. Baudouy, F. Bauer, M. Bauer, T. Baumgartner, I. Bautista-Guzmán, C. Bayındır, F. Beaudette, F. Bedeschi, M. Béguin, I. Bellafont, L. Bellagamba, N. Bellegarde, E. Belli, E. Bellingeri, F. Bellini, G. Bellomo, S. Belomestnykh, G. Bencivenni, M. Benedikt, G. Bernardi, J. Bernardi, C. Bernet, J. M. Bernhardt, C. Bernini, C. Berriaud, A. Bertarelli, S. Bertolucci, M. I. Besana, M. Besançon, O. Beznosov, P. Bhat, C. Bhat, M. E. Biagini, J.-L. Biarrotte, A. Bibet Chevalier, E. R. Bielert, M. Biglietti, G. M. Bilei, B. Bilki, C. Biscari, F. Bishara, O. R. Blanco-García, F. R. Blánquez, F. Blekman, A. Blondel, J. Blümlein, T. Boccali, R. Boels, S. A. Bogacz, A. Bogomyagkov, O. Boine-Frankenheim, M. J. Boland, S. Bologna, O. Bolukbasi, M. Bomben, S. Bondarenko, M. Bonvini, E. Boos, B. Bordini, F. Bordry, G. Borghello, L. Borgonovi, S. Borowka, D. Bortoletto, D. Boscherini, M. Boscolo, S. Boselli, R. R. Bosley, F. Bossu, C. Botta, L. Bottura, R. Boughezal, D. Boutin, G. Bovone, I. Božović Jelisavc̆ić, A. Bozbey, C. Bozzi, D. Bozzini, V. Braccini, S. Braibant-Giacomelli, J. Bramante, P. Braun-Munzinger, J. A. Briffa, D. Britzger, S. J. Brodsky, J. J. Brooke, R. Bruce, P. Brückman De Renstrom, E. Bruna, O. Brüning, O. Brunner, K. Brunner, P. Bruzzone, X. Buffat, E. Bulyak, F. Burkart, H. Burkhardt, J.-P. Burnet, F. Butin, D. Buttazzo, A. Butterworth, M. Caccia, Y. Cai, B. Caiffi, V. Cairo, O. Cakir, R. Calaga, S. Calatroni, G. Calderini, G. Calderola, A. Caliskan, D. Calvet, M. Calviani, J. M. Camalich, P. Camarri, M. Campanelli, T. Camporesi, A. C. Canbay, A. Canepa, E. Cantergiani, D. Cantore-Cavalli, M. Capeans, R. Cardarelli, U. Cardella, A. Cardini, C. M. Carloni Calame, F. Carra, S. Carra, A. Carvalho, S. Casalbuoni, J. Casas, M. Cascella, P. Castelnovo, G. Castorina, G. Catalano, V. Cavasinni, E. Cazzato, E. Cennini, A. Cerri, F. Cerutti, J. Cervantes, I. Chaikovska, J. Chakrabortty, M. Chala, M. Chamizo-Llatas, H. Chanal, D. Chanal, S. Chance, A. Chancé, P. Charitos, J. Charles, T. K. Charles, S. Chattopadhyay, R. Chehab, S. V. Chekanov, N. Chen, A. Chernoded, V. Chetvertkova, L. Chevalier, G. Chiarelli, G. Chiarello, M. Chiesa, P. Chiggiato, J. T. Childers, A. Chmielińska, A. Cholakian, P. Chomaz, M. Chorowski, W. Chou, M. Chrzaszcz, E. Chyhyrynets, G. Cibinetto, A. K. Ciftci, R. Ciftci, R. Cimino, M. Ciuchini, P. J. Clark, Y. Coadou, M. Cobal, A. Coccaro, J. Cogan, E. Cogneras, F. Collamati, C. Colldelram, P. Collier, J. Collot, R. Contino, F. Conventi, C. T. A. Cook, L. Cooley, G. Corcella, A. S. Cornell, G. H. Corral, H. Correia-Rodrigues, F. Costanza, P. Costa Pinto, F. Couderc, J. Coupard, N. Craig, I. Crespo Garrido, A. Crivellin, J. F. Croteau, M. Crouch, E. Cruz Alaniz, B. Curé, J. Curti, D. Curtin, M. Czech, C. Dachauer, R. T. D’Agnolo, M. Daibo, A. Dainese, B. Dalena, A. Daljevec, W. Dallapiazza, L. D’Aloia Schwartzentruber, M. Dam, G. D’Ambrosio, S. P. Das, S. DasBakshi, W. da Silva, G. G. da Silveira, V. D’Auria, S. D’Auria, A. David, T. Davidek, A. Deandrea, J. de Blas, C. J. Debono, S. De Curtis, N. De Filippis, D. de Florian, S. Deghaye, S. J. de Jong, C. Del Bo, V. Del Duca, D. Delikaris, F. Deliot, A. Dell’Acqua, L. Delle Rose, M. Delmastro, E. De Lucia, M. Demarteau, D. Denegri, L. Deniau, D. Denisov, H. Denizli, A. Denner, D. d’Enterria, G. de Rijk, A. De Roeck, F. Derue, O. Deschamps, S. Descotes-Genon, P. S. B. Dev, J. B. de Vivie de Régie, R. K. Dewanjee, A. Di Ciaccio, A. Di Cicco, B. M. Dillon, B. Di Micco, P. Di Nezza, S. Di Vita, A. Doblhammer, A. Dominjon, M. D’Onofrio, F. Dordei, A. Drago, P. Draper, Z. Drasal, M. Drewes, L. Duarte, I. Dubovyk, P. Duda, A. Dudarev, L. Dudko, D. Duellmann, M. Dünser, T. du Pree, M. Durante, H. Duran Yildiz, S. Dutta, F. Duval, J. M. Duval, Ya. Dydyshka, B. Dziewit, S. Eisenhardt, M. Eisterer, T. Ekelof, D. El Khechen, S. A. Ellis, J. Ellis, J. A. Ellison, K. Elsener, M. Elsing, Y. Enari, C. Englert, H. Eriksson, K. J. Eskola, L. S. Esposito, O. Etisken, E. Etzion, P. Fabbricatore, A. Falkowski, A. Falou, J. Faltova, J. Fan, L. Fanò, A. Farilla, R. Farinelli, S. Farinon, D. A. Faroughy, S. D. Fartoukh, A. Faus-Golfe, W. J. Fawcett, G. Felici, L. Felsberger, C. Ferdeghini, A. M. Fernandez Navarro, A. Fernández-Téllez, J. Ferradas Troitino, G. Ferrara, R. Ferrari, L. Ferreira, P. Ferreira da Silva, G. Ferrera, F. Ferro, M. Fiascaris, S. Fiorendi, C. Fiorio, O. Fischer, E. Fischer, W. Flieger, M. Florio, D. Fonnesu, E. Fontanesi, N. Foppiani, K. Foraz, D. Forkel-Wirth, S. Forte, M. Fouaidy, D. Fournier, T. Fowler, J. Fox, P. Francavilla, R. Franceschini, S. Franchino, E. Franco, A. Freitas, B. Fuks, K. Furukawa, S. V. Furuseth, E. Gabrielli, A. Gaddi, M. Galanti, E. Gallo, S. Ganjour, Jia. Gao, Jie. Gao, V. Garcia Diaz, M. García Pérez, L. García Tabarés, C. Garion, M. V. Garzelli, I. Garzia, S. M. Gascon-Shotkin, G. Gaudio, P. Gay, S.-F. Ge, T. Gehrmann, M. H. Genest, R. Gerard, F. Gerigk, H. Gerwig, P. Giacomelli, S. Giagu, E. Gianfelice-Wendt, F. Gianotti, F. Giffoni, S. S. Gilardoni, M. Gil Costa, M. Giovannetti, M. Giovannozzi, P. Giubellino, G. F. Giudice, A. Giunta, L. K. Gladilin, S. Glukhov, J. Gluza, G. Gobbi, B. Goddard, F. Goertz, T. Golling, D. Gonçalves, V. P. Goncalves, R. Gonçalo, L. A. Gonzalez Gomez, S. Gorgi Zadeh, G. Gorine, E. Gorini, S. A. Gourlay, L. Gouskos, F. Grancagnolo, A. Grassellino, A. Grau, E. Graverini, H. M. Gray, Ma. Greco, Mi. Greco, J.-L. Grenard, O. Grimm, C. Grojean, V. A. Gromov, J. F. Grosse-Oetringhaus, A. Grudiev, K. Grzanka, J. Gu, D. Guadagnoli, V. Guidi, S. Guiducci, G. Guillermo Canton, Y. O. Günaydin, R. Gupta, R. S. Gupta, J. Gutierrez, J. Gutleber, C. Guyot, V. Guzey, C. Gwenlan, Ch. Haberstroh, B. Hacışahinoğlu, B. Haerer, K. Hahn, T. Hahn, A. Hammad, C. Han, M. Hance, A. Hannah, P. C. Harris, C. Hati, S. Haug, J. Hauptman, V. Haurylavets, H-J. He, A. Hegglin, B. Hegner, K. Heinemann, S. Heinemeyer, C. Helsens, Ana. Henriques, And. Henriques, P. Hernandez, R. J. Hernández-Pinto, J. Hernandez-Sanchez, T. Herzig, I. Hiekkanen, W. Hillert, T. Hoehn, M. Hofer, W. Höfle, F. Holdener, S. Holleis, B. Holzer, D. K. Hong, C. G. Honorato, S. C. Hopkins, J. Hrdinka, F. Hug, B. Humann, H. Humer, T. Hurth, A. Hutton, G. Iacobucci, N. Ibarrola, L. Iconomidou-Fayard, K. Ilyina-Brunner, J. Incandela, A. Infantino, V. Ippolito, M. Ishino, R. Islam, H. Ita, A. Ivanovs, S. Iwamoto, A. Iyer, S. Izquierdo Bermudez, S. Jadach, D. O. Jamin, P. Janot, P. Jarry, A. Jeff, P. Jenny, E. Jensen, M. Jensen, X. Jiang, J. M. Jiménez, M. A. Jones, O. R. Jones, J. M. Jowett, S. Jung, W. Kaabi, M. Kado, K. Kahle, L. Kalinovskaya, J. Kalinowski, J. F. Kamenik, K. Kannike, S. O. Kara, H. Karadeniz, V. Karaventzas, I. Karpov, S. Kartal, A. Karyukhin, V. Kashikhin, J. Katharina Behr, U. Kaya, J. Keintzel, P. A. Keinz, K. Keppel, R. Kersevan, K. Kershaw, H. Khanpour, S. Khatibi, M. Khatiri Yanehsari, V. V. Khoze, J. Kieseler, A. Kilic, A. Kilpinen, Y.-K. Kim, D. W. Kim, U. Klein, M. Klein, F. Kling, N. Klinkenberg, S. Klöppel, M. Klute, V. I. Klyukhin, M. Knecht, B. Kniehl, F. Kocak, C. Koeberl, A. M. Kolano, A. Kollegger, K. Kołodziej, A. A. Kolomiets, J. Komppula, I. Koop, P. Koppenburg, M. Koratzinos, M. Kordiaczyńska, M. Korjik, O. Kortner, P. Kostka, W. Kotlarski, C. Kotnig, T. Köttig, A. V. Kotwal, A. D. Kovalenko, S. Kowalski, J. Kozaczuk, G. A. Kozlov, S. S. Kozub, A. M. Krainer, T. Kramer, M. Krämer, M. Krammer, A. A. Krasnov, F. Krauss, K. Kravalis, L. Kretzschmar, R. M. Kriske, H. Kritscher, P. Krkotic, H. Kroha, M. Kucharczyk, S. Kuday, A. Kuendig, G. Kuhlmann, A. Kulesza, Mi. Kumar, Mu. Kumar, A. Kusina, S. Kuttimalai, M. Kuze, T. Kwon, F. Lackner, M. Lackner, E. La Francesca, M. Laine, G. Lamanna, S. La Mendola, E. Lançon, G. Landsberg, P. Langacker, C. Lange, A. Langner, A. J. Lankford, J. P. Lansberg, T. Lari, P. J. Laycock, P. Lebrun, A. Lechner, K. Lee, S. Lee, R. Lee, T. Lefevre, P. Le Guen, T. Lehtinen, S. B. Leith, P. Lenzi, E. Leogrande, C. Leonidopoulos, I. Leon-Monzon, G. Lerner, O. Leroy, T. Lesiak, P. Lévai, A. Leveratto, E. Levichev, G. Li, S. Li, R. Li, D. Liberati, M. Liepe, D. A. Lissauer, Z. Liu, A. Lobko, E. Locci, E. Logothetis Agaliotis, M. P. Lombardo, A. J. Long, C. Lorin, R. Losito, A. Louzguiti, I. Low, D. Lucchesi, M. T. Lucchini, A. Luciani, M. Lueckhof, A. J. G. Lunt, M. Luzum, D. A. Lyubimtsev, M. Maggiora, N. Magnin, M. A. Mahmoud, F. Mahmoudi, J. Maitre, V. Makarenko, A. Malagoli, J. Malclés, L. Malgeri, P. J. Mallon, F. Maltoni, S. Malvezzi, O. B. Malyshev, G. Mancinelli, P. Mandrik, P. Manfrinetti, M. Mangano, P. Manil, M. Mannelli, G. Marchiori, F. Marhauser, V. Mariani, V. Marinozzi, S. Mariotto, P. Marquard, C. Marquet, T. Marriott-Dodington, R. Martin, O. Martin, J. Martin Camalich, T. Martinez, H. Martinez Bruzual, M. I. Martínez-Hernández, D. E. Martins, S. Marzani, D. Marzocca, L. Marzola, S. Masciocchi, I. Masina, A. Massimiliano, A. Massironi, T. Masubuchi, V. A. Matveev, M. A. Mazzoni, M. McCullough, P. A. McIntosh, P. Meade, L. Medina, A. Meier, J. Meignan, B. Mele, J. G. Mendes Saraiva, F. Menez, M. Mentink, E. Meoni, P. Meridiani, M. Merk, P. Mermod, V. Mertens, L. Mether, E. Métral, M. Migliorati, A. Milanese, C. Milardi, G. Milhano, B. L. Militsyn, F. Millet, I. Minashvili, J. V. Minervini, L. S. Miralles, D. Mirarchi, S. Mishima, D. P. Missiaen, G. Mitselmakher, T. Mitsuhashi, J. Mnich, M. Mohammadi Najafabadi, R. N. Mohapatra, N. Mokhov, J. G. Molson, R. Monge, C. Montag, G. Montagna, S. Monteil, G. Montenero, E. Montesinos, F. Moortgat, N. Morange, G. Morello, M. Moreno Llácer, M. Moretti, S. Moretti, A. K. Morley, A. Moros, I. Morozov, V. Morretta, M. Morrone, A. Mostacci, S. Muanza, N. Muchnoi, M. Mühlegger, M. Mulder, M. Mulders, B. Müller, F. Müller, A.-S. Müller, J. Munilla, M. J. Murray, Y. Muttoni, S. Myers, M. Mylona, J. Nachtman, T. Nakamoto, M. Nardecchia, G. Nardini, P. Nason, Z. Nergiz, A. V. Nesterenko, A. Nettsträter, C. Neubüser, J. Neundorf, F. Niccoli, O. Nicrosini, Y. Nie, U. Niedermayer, J. Niedziela, A. Niemi, S. A. Nikitin, A. Nisati, J. M. No, M. Nonis, Y. Nosochkov, M. Novák, A. Novokhatski, J. M. O’Callaghan, C. Ochando, S. Ogur, K. Ohmi, K. Oide, V. A. Okorokov, Y. Okumura, C. Oleari, F. I. Olness, Y. Onel, M. Ortino, J. Osborne, P. Osland, T. Otto, K. Y. Oyulmaz, A. Ozansoy, V. Özcan, K. Özdemir, C. E. Pagliarone, H. F. Pais da Silva, E. Palmieri, L. Palumbo, A. Pampaloni, R.-Q. Pan, M. Panareo, O. Panella, G. Panico, G. Panizzo, A. A. Pankov, V. Pantsyrny, C. G. Papadopoulos, A. Papaefstathiou, Y. Papaphilippou, M. A. Parker, V. Parma, M. Pasquali, S. K. Patra, R. Patterson, H. Paukkunen, F. Pauss, S. Peggs, J.-P. Penttinen, G. Peón, E. E. Perepelkin, E. Perez, J. C. Perez, G. Perez, F. Pérez, E. Perez Codina, J. Perez Morales, M. Perfilov, H. Pernegger, M. Peruzzi, C. Pes, K. Peters, S. Petracca, F. Petriello, L. Pezzotti, S. Pfeiffer, F. Piccinini, T. Pieloni, M. Pierini, H. Pikhartova, G. Pikurs, E. Pilicer, P. Piminov, C. Pira, R. Pittau, W. Płaczek, M. Plagge, T. Plehn, M.-A. Pleier, M. Płoskoń, M. Podeur, H. Podlech, T. Podzorny, L. Poggioli, A. Poiron, G. Polesello, M. Poli Lener, A. Polini, J. Polinski, S. M. Polozov, L. Ponce, M. Pont, L. Pontecorvo, T. Portaluri, K. Potamianos, C. Prasse, M. Prausa, A. Preinerstorfer, E. Premat, T. Price, M. Primavera, F. Prino, M. Prioli, J. Proudfoot, A. Provino, T. Pugnat, N. Pukhaeva, S. Puławski, D. Pulikowski, G. Punzi, M. Putti, A. Pyarelal, H. Quack, M. Quispe, A. Racioppi, H. Rafique, V. Raginel, M. Raidal, N. S. Ramírez-Uribe, M. J. Ramsey-Musolf, R. Rata, P. Ratoff, F. Ravotti, P. Rebello Teles, M. Reboud, S. Redaelli, E. Renner, A. E. Rentería-Olivo, M. Rescigno, J. Reuter, A. Ribon, A. M. Ricci, W. Riegler, S. Riemann, B. Riemann, T. Riemann, J. M. Rifflet, R. A. Rimmer, R. Rinaldesi, L. Rinolfi, O. Rios Rubiras, T. Risselada, A. Rivetti, L. Rivkin, T. Rizzo, T. Robens, F. Robert, A. J. Robson, E. Rochepault, C. Roda, G. Rodrigo, M. Rodríguez-Cahuantzi, C. Rogan, M. Roig, S. Rojas-Torres, J. Rojo, G. Rolandi, G. Rolando, P. Roloff, A. Romanenko, A. Romanov, F. Roncarolo, A. Rosado Sanchez, G. Rosaz, L. Rossi, A. Rossi, R. Rossmanith, B. Rousset, C. Royon, X. Ruan, I. Ruehl, V. Ruhlmann-Kleider, R. Ruiz, L. Rumyantsev, R. Ruprecht, A. I. Ryazanov, A. Saba, R. Sadykov, D. Saez de Jauregui, M. Sahin, B. Sailer, M. Saito, F. Sala, G. P. Salam, J. Salfeld-Nebgen, C. A. Salgado, S. Salini, J. M. Sallese, T. Salmi, A. Salzburger, O. A. Sampayo, S. Sanfilippo, J. Santiago, E. Santopinto, R. Santoro, A. Sanz Ull, X. Sarasola, I. H. Sarpün, M. Sauvain, S. Savelyeva, R. Sawada, G. F. R. Sborlini, A. Schaffer, M. Schaumann, M. Schenk, C. Scheuerlein, I. Schienbein, K. Schlenga, H. Schmickler, R. Schmidt, D. Schoerling, A. Schoning, T. Schörner-Sadenius, M. Schott, D. Schulte, P. Schwaller, C. Schwanenberger, P. Schwemling, N. Schwerg, L. Scibile, A. Sciuto, E. Scomparin, C. Sebastiani, B. Seeber, M. Segreti, P. Selva, M. Selvaggi, C. Senatore, A. Senol, L. Serin, M. Serluca, N. Serra, A. Seryi, L. Sestini, A. Sfyrla, M. Shaposhnikov, E. Shaposhnikova, B. Yu. Sharkov, D. Shatilov, J. Shelton, V. Shiltsev, I. P. Shipsey, G. D. Shirkov, A. Shivaji, D. Shwartz, T. Sian, S. Sidorov, A. Siemko, L. Silvestrini, N. Simand, F. Simon, B. K. Singh, A. Siódmok, Y. Sirois, E. Sirtori, R. Sirvinskaite, B. Sitar, T. Sjöstrand, P. Skands, E. Skordis, K. Skovpen, M. Skrzypek, E. Slade, P. Slavich, R. Slovak, V. Smaluk, V. Smirnov, W. Snoeys, L. Soffi, P. Sollander, O. Solovyanov, H. K. Soltveit, H. Song, P. Sopicki, M. Sorbi, L. Spallino, M. Spannowsky, B. Spataro, P. Sphicas, H. Spiesberger, P. Spiller, M. Spira, T. Srivastava, J. Stachel, A. Stakia, J. L. Stanyard, E. Starchenko, A. Yu. Starikov, A. M. Staśto, M. Statera, R. Steerenberg, J. Steggemann, A. Stenvall, F. Stivanello, D. Stöckinger, L. S. Stoel, M. Stöger-Pollach, B. Strauss, M. Stuart, G. Stupakov, S. Su, A. Sublet, K. Sugita, L. Sulak, M. K. Sullivan, S. Sultansoy, T. Sumida, K. Suzuki, G. Sylva, M. J. Syphers, A. Sznajder, M. Taborelli, N. A. Tahir, E. Tal Hod, M. Takeuchi, C. Tambasco, J. Tanaka, K. Tang, I. Tapan, S. Taroni, G. F. Tartarelli, G. Tassielli, L. Tavian, T. M. Taylor, G. N. Taylor, A. M. Teixeira, G. Tejeda-Muñoz, V. I. Telnov, R. Tenchini, H. H. J. ten Kate, K. Terashi, A. Tesi, M. Testa, C. Tetrel, D. Teytelman, J. Thaler, A. Thamm, S. Thomas, M. T. Tiirakari, V. Tikhomirov, D. Tikhonov, H. Timko, V. Tisserand, L. M. Tkachenko, J. Tkaczuk, J. Ph. Tock, B. Todd, E. Todesco, R. Tomás Garcia, D. Tommasini, G. Tonelli, F. Toral, T. Torims, R. Torre, Z. Townsend, R. Trant, D. Treille, L. Trentadue, A. Tricoli, A. Tricomi, W. Trischuk, I. S. Tropin, B. Tuchming, A. A. Tudora, B. Turbiarz, I. Turk Cakir, M. Turri, T. Tydecks, J. Usovitsch, J. Uythoven, R. Vaglio, A. Valassi, F. Valchkova, M. A. Valdivia Garcia, P. Valente, R. U. Valente, A.-M. Valente-Feliciano, G. Valentino, L. Vale Silva, J. M. Valet, R. Valizadeh, J. W. F. Valle, S. Vallecorsa, G. Vallone, M. van Leeuwen, U. H. van Rienen, L. van Riesen-Haupt, M. Varasteh, L. Vecchi, P. Vedrine, G. Velev, R. Veness, A. Ventura, W. Venturini Delsolaro, M. Verducci, C. B. Verhaaren, C. Vernieri, A. P. Verweij, O. Verwilligen, O. Viazlo, A. Vicini, G. Viehhauser, N. Vignaroli, M. Vignolo, A. Vitrano, I. Vivarelli, S. Vlachos, M. Vogel, D. M. Vogt, V. Völkl, P. Volkov, G. Volpini, J. von Ahnen, G. Vorotnikov, G. G. Voutsinas, V. Vysotsky, U. Wagner, R. Wallny, L.-T. Wang, R. Wang, K. Wang, B. F. L. Ward, T. P. Watson, N. K. Watson, Z. Wa̧s, C. Weiland, S. Weinzierl, C. P. Welsch, J. Wenninger, M. Widorski, U. A. Wiedemann, H.-U. Wienands, G. Wilkinson, P. H. Williams, A. Winter, A. Wohlfahrt, T. Wojtoń, D. Wollmann, J. Womersley, D. Woog, X. Wu, A. Wulzer, M. K. Yanehsari, G. Yang, H. J. Yang, W.-M. Yao, E. Yazgan, V. Yermolchik, Ay. Yilmaz, Al. Yilmaz, H.-D. Yoo, S. A. Yost, T. You, C. Young, T.-T. Yu, F. Yu, A. Zaborowska, S. G. Zadeh, M. Zahnd, M. Zanetti, L. Zanotto, L. Zawiejski, P. Zeiler, M. Zerlauth, S. M. Zernov, G. Zevi Dell Porta, Z. Zhang, Y. Zhang, C. Zhang, H. Zhang, Z. Zhao, Y.-M. Zhong, J. Zhou, D. Zhou, P. Zhuang, G. Zick, F. Zimmermann, J. Zinn-Justin, L. Zivkovic, A. V. Zlobin, M. Zobov, J. Zupan, J. Zurita, and The FCC Collaboration

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract We review the physics opportunities of the Future Circular Collider, covering its e+e-, pp, ep and heavy ion programmes. We describe the measurement capabilities of each FCC component, addressing the study of electroweak, Higgs and strong interactions, the top quark and flavour, as well as phenomena beyond the Standard Model. We highlight the synergy and complementarity of the different colliders, which will contribute to a uniquely coherent and ambitious research programme, providing an unmatchable combination of precision and sensitivity to new physics.

Published
2019
Full Text
View/download PDF

10. Mechanical Design of FalconD, a Nb$_3$Sn Cos$\theta$ Short Model Dipole for the FCC

Author

A. Pampaloni, G. Bellomo, S. Burioli, B. Caiffi, E. De Matteis, P. Fabbricatore, S. Farinon, H. Felice, F. Lackner, F. Levi, S. Mariotto, R. Musenich, M. Prioli, M. Sorbi, M. Statera, D. Tommasini, and R. U. Valente

Subjects
Electrical and Electronic Engineering, Condensed Matter Physics, Electronic, Optical and Magnetic Materials
Published
2022

12. Blood Cyclosporine Level Soon After Kidney Transplantation is a Major Determinant of Rejection: Insights From the Mycophenolate Steroid-Sparing Trial

Author

D. Donati, G. Segoloni, Borislav D. Dimitrov, S. Sandrini, Bogdan Ene Iordache, G. Remuzzi, G. Mourad, Flavio Gaspari, Mariadomenica Lesti, Dario Cattaneo, S. Federico, P. Rigotti, J.-L. Bosmans, V. Sparacino, N. Perico, Eliana Gotti, Piero Ruggenenti, U. Valente, M. Salvadori, Gotti, E, Perico, N, Gaspari, F, Cattaneo, D, Lesti, Md, Ruggenenti, P, Segoloni, G, Salvadori, M, Rigotti, P, Valente, U, Donati, D, Sandrini, S, Federico, Stefano, Sparacino, V, Mourad, G, Bosmans, Jl, Dimitrov, Bd, Iordache, Be, and Remuzzi, G.

Subjects
Graft Rejection, Male, Mycophenolate Mofetil, medicine.medical_specialty, medicine.drug_class, Biopsy, T-Lymphocytes, Urinary system, Urology, Rejection, Statistics, Nonparametric, Mycophenolic acid, Humans, Kidney Transplantation, Cyclosporine, Mycophenolate Steroid Sparing Trial, Pharmacokinetics, Adrenal Cortex Hormones, medicine, Kidney transplantation, Analysis of Variance, Clinical Trials as Topic, Transplantation, Kidney, business.industry, Mycophenolic Acid, medicine.disease, Ciclosporin, Treatment Outcome, medicine.anatomical_structure, Area Under Curve, Creatinine, Multivariate Analysis, Immunology, cyclosporine level, Regression Analysis, Corticosteroid, Female, Surgery, Drug Monitoring, business, Immunosuppressive Agents, medicine.drug
Abstract

Target organs express antigens directly recognized by antigen-specific T cells, thereby precipitating rejection. When early T-cell activation is inhibited, there is a low risk of rejection. We sought to determine the predictive values of serial posttransplant blood cyclosporine trough (C(0)) concentrations to minimize the risk for a first rejection episode compared with 2-hour postdose (C(2)) drug concentrations. The final aim of the study was to identify a concentration range for the best predictive pharmacokinetic parameter that should be targeted to reduce the risk of rejection. This possibility was explored in 334 de novo kidney transplant recipients who participated in the prospective, multicenter Mycophenolate Steroid-Sparing Trial. Among measurements performed during the first 6 months postsurgery, cyclosporine C(0) levels measured early after transplantation were the strongest predictor of acute graft rejection. Levels within 300 to 440 ng/mL were associated with the lowest risk of rejection, while patients with levels lower than 300 ng/mL showed a more than double risk. Cyclosporine trough values predicted allograft rejection with an accuracy of 74%, while C(2) levels had no predictive value. These findings underline the need to target cyclosporine therapy early posttransplant to modulate T-cell activation.

Published
2005

13. Modifications of cerebral vascular resistance and autoregulation after graft reperfusion during human orthotopic liver transplantation

Author

G, Ardizzone, A, Arrigo, F, Panaro, M, Centanaro, M, Demartini, A, Pellizzari, A, Cifelli, T M, Jarzembowski, T M, Jarzembowsky, U, Valente, and C, Siani

Subjects
Male, Orthotopic liver transplantation, Cerebral autoregulation, Monitoring, Intraoperative, Cerebral Autoregulation, Homeostasis, Humans, Medicine, Autoregulation, Phenylephrine, Transplantation, business.industry, Transcranial Doppler, Cerebral Vascular Resistance, Middle Aged, Liver Transplantation, medicine.anatomical_structure, Blood pressure, Cerebral blood flow, Cerebrovascular Circulation, Anesthesia, Reperfusion, Vascular resistance, Female, Vascular Resistance, Surgery, business, Blood Flow Velocity, medicine.drug
Abstract

We have studied cerebral blood flow velocity (CBFV) and cerebral autoregulation (CA) in 23 orthotopic liver transplantation (OLT) patients using transcranial doppler. CBFV was continuously recorded using a fixed (helmet) 2-Mz probe through the trans-temporal window. CA changes were studied using a linear regression analysis of percentile changes in CBFV and mean arterial blood pressure (MABP) after phenylephrine infusion compared with baseline. Pearson's “r” coefficient was considered an index of CA. In case of autoregulation is lost “r” tends to 1, thus representing complete dependence of CBFV on MABP. We regarded the slope coefficient parameter “S” as an index of cerebral vascular resistance (CVR), namely, the ratio of the corresponding variations of CBFV to MABP. Wilcoxon test showed a significant increase in both “r” and “S” between the anhepatic versus postreperfusion phases (within the first hour) and versus recovery in the neohepatic phase (end of surgery). A decreased CVR was observed within the first hour after graft reperfusion producing a loss of CA. These phenomena lead to an increase of CBFV and exposed the brain to hyperperfusion.

Published
2004

14. A Bayesian methodology to improve prediction of early graft loss after liver transplantation derived from the Liver Match study

Author

Mario Angelico, Alessandra Nardi, Renato Romagnoli, Tania Marianelli, Stefano Ginanni Corradini, Francesco Tandoi, Caius Gavrila, Mauro Salizzoni, Antonio D. Pinna, Umberto Cillo, Bruno Gridelli, Luciano G. De Carlis, Michele Colledan, Giorgio E. Gerunda, Alessandro Nanni Costa, Mario Strazzabosco, M. Angelico, U. Cillo, S. Fagiuoli, M. Strazzabosco, P. Caraceni, P.L. Toniutto, A. Nanni Costa, Torino M. Salizzoni, R. Romagnoli, G. Bertolotti, D. Patrono, L. De Carlis, A. Slim, J.M.E. Mangoni, G. Rossi, L. Caccamo, B. Antonelli, V. Mazzaferro, E. Regalia, C. Sposito, M. Colledan, V. Corno, F. Tagliabue, S. Marin, A. Vitale, E. Gringeri, M. Donataccio, D. Donataccio, U. Baccarani, D. Lorenzin, D. Bitetto, U. Valente, M. Gelli, P. Cupo, G.E. Gerunda, G. Rompianesi, A.D. Pinna, G.L. Grazi, A. Cucchetti, C. Zanfi, A. Risaliti, M.G. Faraci, G. Tisone, A. Anselmo, I. Lenci, D. Sforza, S. Agnes, M. Di Mugno, A.W. Avolio, G.M. Ettorre, L. Miglioresi, G. Vennarecci, P. Berloco, M. Rossi, S. Ginanni Corradini, A. Molinaro, F. Calise, V. Scuderi, O. Cuomo, C. Migliaccio, L. Lupo, G. Notarnicola, B. Gridelli, R. Volpes, S. Li Petri, F. Zamboni, G. Carbotta, S. Dedola, A. Nardi, T. Marianelli, C. Gavrila, A. Ricci, F. Vespasiano, Angelico, M., Nardi, A., Romagnoli, R., Marianelli, T., Corradini, S. G., Tandoi, F., Gavrila, C., Salizzoni, M., Pinna, A. D., Cillo, U., Gridelli, B., De Carlis, L. G., Colledan, M., Gerunda, G. E., Costa, A. N., Strazzabosco, M., Fagiuoli, S., Caraceni, P., Toniutto, P. L., Sal-izzoni, T. M., Bertolotti, G., Patrono, D., Decarlis, L., Slim, A., Mangoni, J. M. E., Rossi, G., Caccamo, L., Antonelli, B., Mazzaferro, V., Regalia, E., Sposito, C., Corno, V., Marin, S., Vitale, A., Gringeri, E., Donataccio, M., Donataccio, D., Baccarani, U., Lorenzin, D., Bitetto, D., Valente, U., Gelli, M., Cupo, P., Rompianesi, G., Grazi, G. L., Cucchetti, A., Zanfi, C., Risaliti, A., Faraci, M. G., Tisone, G., Anselmo, A., Lenci, I., Sforza, D., Agnes, S., Di Mugno, M., Avolio, A. M., Ettorre, G. M., Miglioresi, L., Vennarecci, G., Berloco, P., Rossi, M., Corradini, G., Molinaro, A., Calise, F., Scuderi, V., Cuomo, O., Migliaccio, C., Lupo, L., Notarnicola, G., Volpes, R., Lipetri, S., Zamboni, G., Carbotta, G., Dedola, S., Angelico, M, Nardi, A, Romagnoli, R, Marianelli, T, Corradini, S, Tandoi, F, Gavrila, C, Salizzoni, M, Pinna, A, Cillo, U, Gridelli, B, DE CARLIS, L, Colledan, M, Gerunda, G, Costa, A, Strazzabosco, M, and Fagiuoli, S

Subjects
Graft Rejection, Male, liver match, Multivariate analysis, medicine.medical_treatment, Settore MED/18 - CHIRURGIA GENERALE, Disease, Liver transplantation, Body Mass Index, Cohort Studies, MED/12 - GASTROENTEROLOGIA, Risk Factors, liver transplantation, early graft loss, Age Factor, Prospective Studies, Multivariate Analysi, hepatitis c, donor risk index, donor-recipient match, graft failure, transplantation outcome, risk factors, Donor Risk Index, Donor-recipient match, Graft failure, Hepatitis C, Risk factors, Transplantation outcome, Settore MED/12 - Gastroenterologia, Cold Ischemia, Graft Survival, Age Factors, Gastroenterology, Middle Aged, Tissue Donors, Treatment Outcome, Italy, Cohort, Female, Human, Adult, United Network for Organ Sharing, medicine.medical_specialty, Tissue Donor, Delayed Graft Function, Bayesan methodology, Risk Assessment, End Stage Liver Disease, medicine, Humans, Aged, Proportional Hazards Models, Hepatology, business.industry, Proportional hazards model, Risk Factor, Bayes Theorem, medicine.disease, Surgery, Prospective Studie, Multivariate Analysis, Proportional Hazards Model, Cohort Studie, Primary Graft Dysfunction, business, Body mass index, Transplantation Outcome
Abstract

Background: To generate a robust predictive model of Early (3 months) Graft Loss after liver transplantation, we used a Bayesian approach to combine evidence from a prospective European cohort (Liver-Match) and the United Network for Organ Sharing registry. Methods: Liver-Match included 1480 consecutive primary liver transplants performed from 2007 to 2009 and the United Network for Organ Sharing a time-matched series of 9740 transplants. There were 173 and 706 Early Graft Loss, respectively. Multivariate analysis identified as significant predictors of Early Graft Loss: donor age, donation after cardiac death, cold ischaemia time, donor body mass index and height, recipient creatinine, bilirubin, disease aetiology, prior upper abdominal surgery and portal thrombosis. Results: A Bayesian Cox model was fitted to Liver-Match data using the United Network for Organ Sharing findings as prior information, allowing to generate an Early Graft Loss-Donor Risk Index and an Early Graft Loss-Recipient Risk Index. A Donor-Recipient Allocation Model, obtained by adding Early Graft Loss-Donor Risk Index to Early Graft Loss-Recipient Risk Index, was then validated in a distinct United Network for Organ Sharing (year 2010) cohort including 2964 transplants. Donor-Recipient Allocation Model updating using the independent Turin Transplant Centre dataset, allowed to predict Early Graft Loss with good accuracy (c-statistic: 0.76). Conclusion: Donor-Recipient Allocation Model allows a reliable donor and recipient-based Early Graft Loss prediction. The Bayesian approach permits to adapt the original Donor-Recipient Allocation Model by incorporating evidence from other cohorts, resulting in significantly improved predictive capability. © 2013 Editrice Gastroenterologica Italiana S.r.l.

Published
2014

15. Alcohol Abstinence and Orthotopic Liver Transplantation in Alcoholic Liver Cirrhosis

Author

F. Piaggio, U. Valente, N. Morelli, C. Ferrari, Maximiliano Gelli, M. Sturdevant, R. Ferrante, G. Immordino, G. Bottino, D. Ghinolfi, M. Casaccia, and E Andorno

Subjects
Adult, Male, Alcoholic liver disease, medicine.medical_specialty, Cirrhosis, medicine.medical_treatment, media_common.quotation_subject, Alcoholic hepatitis, Liver transplantation, Gastroenterology, Liver Cirrhosis, Alcoholic, Internal medicine, medicine, Humans, Liver, Liver Transplantation, Alcoholic Hepatitis, Alcohol Abstinence, Aged, media_common, Transplantation, Ethanol, business.industry, Middle Aged, Abstinence, medicine.disease, Substance Withdrawal Syndrome, Survival Rate, surgical procedures, operative, Female, Surgery, Acute Alcoholic Hepatitis, business
Abstract

Patients diagnosed with acute alcoholic hepatitis (AAH) are routinely managed medically and not considered suitable for orthotopic liver transplantation (OLT). The eligibility for OLT in these patients has been questioned due to the social stigma associated with alcohol abuse, based on the fact that AAH is "self-induced" with an unacceptably high recidivism rate. Many centers in Europe and the United States require abstinence periods between 6 and 12 months before OLT listing. AAH outcomes in the literature are poor, in particular due to patient noncompliance during the immediate 3 months preceeding OLT. Between January 1997 and December 2007, 246 patients were evaluated in our center for alcoholic liver disease: 133 (54%) were listed for OLT (I-OLT), including 110 (83%) who underwent transplantation and 8 (6%) still listed as well as 15 (11%) removed from consideration. One hundred thirteen (46%) patients had no indication for OLT (NO I-OLT), including 18 (16%) who died, 81 (71%) still monitored, and 14 (12%) lost to follow-up. Patient survival rates post-OLT were 79%, 74%, 68%, and 64% at 1, 3, 5, and 10 years, respectively. Explant (native liver) pathologic examination revealed AAH in 8 (7.2%) patients who underwent OLT. In this group, patient survival and the post-OLT recidivism rate were statistically identical to the overall group of transplant recipients.

Published
2009

16. Hepatitis B-core Antibody Positive Donors in Liver Transplantation and Their Impact on Graft Survival: Evidence From The Liver Match Cohort Study

Author

Angelico M, Nardi A, Marianelli T, Caccamo L, Romagnoli R, Tisone G, Pinna AD, Avolio AW, Fagiuoli S, Burra P, Strazzabosco M, Nanni Costa A, U Cillo, P Caraceni, P L Toniutto, M Salizzoni, G Bertolotti, D Patrono, L De Carlis, A Slim, J M E Mangoni, G Rossi, B Antonelli, V Mazzaferro, E Regalia, C Sposito, M Colledan, V Corno, F Tagliabue, S Marin, A Vitale, E Gringeri, M Donataccio, D Donataccio, U Baccarani, D Lorenzin, D Bitetto, U Valente, M Gelli, P Cupo, G E Gerunda, G Rompianesi, G L Grazi, A Cucchetti, C Zanfi, A Risaliti, M G Faraci, A Anselmo, I Lenci, D Sforza, S Agnes, M Di Mugno, G M Ettorre, L Miglioresi, G Vennarecci, Roma Sapienza, P Berloco, M Rossi, S Ginanni-Corradini, A Molinaro, F Calise, V Scuderi, O Cuomo, C Migliaccio, L Lupo, G Notarnicola, B Gridelli, R Volpes, S Li Petri, F Zamboni, G Carbotta, S Dedola, C Gavrila, A Ricci, F Vespasiano, Angelico, M, Nardi, A, Marianelli, T, Caccamo, L, Romagnoli, R, Tisone, G, Pinna, A, Avolio, A, Fagiuoli, S, Burra, P, Strazzabosco, M, Costa, A, M, Angelico, A, Nardi, T, Marianelli, L, Caccamo, R, Romagnoli, G, Tisone, Ad, Pinna, Aw, Avolio, S, Fagiuoli, P, Burra, M, Strazzabosco, A, Nanni Costa, Cillo, U, Caraceni, P, L Toniutto, P, Salizzoni, M, Bertolotti, G, Patrono, D, De Carlis, L, Slim, A, E Mangoni, J M, Rossi, G, Antonelli, B, Mazzaferro, V, Regalia, E, Sposito, C, Colledan, M, Corno, V, Tagliabue, F, Marin, S, Vitale, A, Gringeri, E, Donataccio, M, Donataccio, D, Baccarani, U, Lorenzin, D, Bitetto, D, Valente, U, Gelli, M, Cupo, P, E Gerunda, G, Rompianesi, G, L Grazi, G, Cucchetti, A, Zanfi, C, Risaliti, A, G Faraci, M, Anselmo, A, Lenci, I, Sforza, D, Agnes, S, Di Mugno, M, M Ettorre, G, Miglioresi, L, Vennarecci, G, Sapienza, Roma, Berloco, P, Rossi, M, Ginanni-Corradini, S, Molinaro, A, Calise, F, Scuderi, V, Cuomo, O, Migliaccio, C, Lupo, L, Notarnicola, G, Gridelli, B, Volpes, R, Li Petri, S, Zamboni, F, Carbotta, G, Dedola, S, Gavrila, C, Ricci, A, Vespasiano, F, Mario Angelico, Alessandra Nardi, Tania Marianelli, Lucio Caccamo, Renato Romagnoli, Giuseppe Tisone, Antonio D. Pinna, Alfonso W. Avolio, Stefano Fagiuoli, Patrizia Burra, Mario Strazzabosco, Alessandro Nanni Costa, For the Liver Match Investigators [.., Paolo Caraceni, and ]

Subjects
Male, HBsAg, medicine.medical_treatment, Settore MED/18 - CHIRURGIA GENERALE, graft survival, De novo HBV infection, Donor Risk Index, Donor-recipient matching, HBcAb positive donors, Liver transplantation, medicine.disease_cause, Gastroenterology, Cohort Studies, Model for End-Stage Liver Disease, MED/12 - GASTROENTEROLOGIA, HBcAb positive donor, liver transplantation, Prospective Studies, Prospective cohort study, Settore MED/12 - Gastroenterologia, Hepatitis B Core Antigen, Hazard ratio, Middle Aged, Hepatitis B, Hepatitis B Core Antigens, Tissue Donors, Italy, Hepatocellular carcinoma, HCV, outcome, Female, Human, hbcab positive donors, Adult, medicine.medical_specialty, donor risk index, HBcAb positive, Tissue Donor, survival, donor-recipient matching, Donor Selection, Hepatitis B Antibodie, HBV, liver transplantation, Internal medicine, medicine, Humans, de novo hbv infection, Hepatitis B Antibodies, Donor-recipient matching, HBcAb positive donors, De novo HBV infection, Donor Risk Index, Aged, Hepatitis B virus, Hepatitis, Hepatology, business.industry, LIVER TRANSPLANTATION, medicine.disease, Surgery, Prospective Studie, Liver Transplantation, Graft Survival, Cohort Studie, business
Abstract

Background & Aims: The appropriate allocation of grafts from HBcAb positive donors in liver transplantation is crucial, yet a consensus is still lacking. Methods: We evaluated this issue within Liver Match, a prospective observational Italian study. Data from 1437 consecutive, first transplants performed in 2007-2009 using grafts from deceased heart beating donors were analyzed (median follow-up: 1040 days). Of these, 219 (15.2%) were HBcAb positive. Sixty-six HBcAb positive grafts were allocated to HBsAg positive and 153 to HBsAg negative recipients. Results: 329 graft losses occurred (22.9%): 66 (30.1%) among 219 recipients of HBcAb positive grafts, and 263 (21.6%) among 1218 recipients of HBcAb negative grafts. Graft survival was lower in recipients of HBcAb positive compared to HBcAb negative donors, with unadjusted 3-year graft survival of 0.69 (s.e. 0.032) and 0.77 (0.013), respectively (log-rank, p = 0.0047). After stratifying for recipient HBsAg status, this difference was only observed among HBsAg negative recipients (log rank, p = 0.0007), 3-year graft survival being excellent (0.88, s.e. 0.020) among HBsAg positive recipients, regardless of the HBcAb donor status (log rank, p = 0.4478). Graft loss due to de novo HBV hepatitis occurred only in one patient. At Cox regression, hazard ratios for graft loss were: MELD (1.30 per 10 units, p = 0.0002), donor HBcAb positivity (1.56, p = 0.0015), recipient HBsAg positivity (0.43, p

Published
2012

17. Giant mid-esophageal diverticulum. Conservative treatment of postoperative leakage

Author

S, Dallatomasina, M, Casaccia, M, Chessa, J, Serrano, I, Nardi, B, Troilo, M, Miggino, and U, Valente

Subjects
Male, Reoperation, Thoracic Surgery, Video-Assisted, Jejunostomy, Postoperative Hemorrhage, Abscess, Esophageal Fistula, Postoperative Complications, Thoracotomy, Mediastinal Diseases, Diverticulum, Esophageal, Drainage, Humans, Tomography, X-Ray Computed, Intubation, Gastrointestinal, Aged
Abstract

Mid-esophageal diverticula are rare entities. Only symptomatic patients usually receive surgical treatment. Esophageal leakage is one of the most common complications after these procedures. Though in literature, operative management is the preferred treatment for esophageal fistula, conservative approach is described in case of small leaks. We report a case of an operated giant mid-esophageal diverticulum complicated with an esophageal fistula. The patient underwent a surgical treatment and recovered completely.

Published
2010

18. Split liver transplantation for acute Wilson's disease: new option for urgent recipient?

Author

E, Andorno, M, Miggino, F, Panaro, N, Morelli, G, Bottino, M, Casaccia, T M, Jarzembowski, and U, Valente

Subjects
Adult, Hepatolenticular Degeneration, Acute Disease, Humans, Female, Emergency Treatment, Liver Transplantation
Abstract

Wilson's disease is a rare metabolic disorder that may lead to fulminant hepatitis and subsequent liver failure. Herein, we present a case of split liver transplantation performed on a patient with acute Wilson's disease. A 27-year-old female with acute presentation of Wilson's disease and advanced neurological impairment, received a Right Split liver Graft (Segments: IV, V, VI, VII and VIII) transplant. The graft was obtained by an in situ splitting technique. The graft implantation was performed in a standard fashion. No acute rejection episodes of the organ occurred. The postoperative course was uneventful. The graft function, ceruloplasmine level and copper levels progressively normalized. The patient totally recovered from neurological symptoms and the Kayser-Fleischer rings disappeared within one month. At 13 months of follow-up, the patient presented with no symptoms and in good condition. The current literature reports high preoperative mortality rate in patients that underwent partial liver graft for acute hepatic failure. However, our experience indicates that in situ split technique of liver may be a feasible and effective alternative to whole graft transplantation in urgent cases. Moreover, to our knowledge, this is the first successfully case of in situ split liver transplantation for acute Wilson's disease described in literature.

Published
2007

19. A randomized study comparing three cyclosporine-based regimens in cadaveric renal transplantation: results at 7 years

Author

F Mastrangelo, Marco Castagneto, P Altieri, V. Cambi, G.B Piredda, A Tarantino, U. Valente, C Ponticelli, G P Segoloni, Stefano Federico, F Pisani, M Salvadori, G Rizzo, M Messina, Mario Carmellini, L. Arisi, G. Montagnino, and Maria Laura Cossu

Subjects
Adult, medicine.medical_specialty, Time Factors, Adolescent, medicine.medical_treatment, Azathioprine, law.invention, Pharmacotherapy, Randomized controlled trial, law, medicine, Humans, Survival rate, Aged, Transplantation, business.industry, Graft Survival, Immunosuppression, Middle Aged, Ciclosporin, Kidney Transplantation, Surgery, Survival Rate, Clinical trial, Creatinine, Cyclosporine, Drug Therapy, Combination, Steroids, business, Immunosuppressive Agents, Follow-Up Studies, medicine.drug
Abstract

AFTER the worldwide adoption of cyclosporine (CsA) for maintenance immunosuppression, a striking improvement in renal transplant survival has been obtained. Recipients of first cadaver allografts commonly achieve 1-year graft survival approaching 90% with low patient mortality. Yet, in spite of the large experience accumulated with CsA, we still do not know which CsA-based protocol is better in the long-term. Although CsA was administered alone in clinical transplantation at the beginning of its use, steroid-free immunosuppression has not been accepted in most transplant centers because of the risk of nephrotoxicity associated with the large dose of CsA required for successful immunosuppresion and the increased risk of acute rejection, which could expose patients to chronic graft dysfunction in the long term. The results obtained using an association between CsA and steroids (double therapy) or CsA, steroids, and azathioprine (triple therapy) did not show any significant differences in either the patient or graft survival rates or in the incidence of drug-related complications. We recently reported the results of a randomized trial simultaneously comparing the three treatment schemes. We have now reanalyzed the data by extending the follow-up at 7 years after transplantation.

Published
1998

20. Precision electroweak measurements on the Z resonance

Author

Schael, S Barate, R Bruneliere, R Buskulic, D De Bonis, I Decamp, D Ghez, P Goy, C Jezequel, S Lees, JP and Lucotte, A Martin, F Merle, E Minard, MN Nief, JY and Odier, P Pietrzyk, B Trocme, B Bravo, S Casado, MP and Chmeissani, M Comas, P Crespo, JM Fernandez, E and Fernandez-Bosman, M Garrido, L Grauges, E Juste, A and Martinez, M Merino, G Miquel, R Mir, LM Orteu, S and Pacheco, A Park, IC Perlas, J Riu, I Ruiz, H and Sanchez, F Colaleo, A Creanza, D De Filippis, N de Palma, M Iaselli, G Maggi, G Maggi, M Nuzzo, S and Ranieri, A Raso, G Ruggieri, F Selvaggi, G Silvestris, L and Tempesta, P Tricomi, A Zito, G Huang, X Lin, J and Ouyang, Q Wang, T Xie, Y Xu, R Xue, S Zhang, J and Zhang, L Zhao, W Abbaneo, D Bazarko, A Becker, U and Boix, G Bird, F Blucher, E Bonvicini, B Bright-Thomas, P and Barklow, T Buchmuller, O Cattaneo, M Cerutti, F and Ciulli, V Clerbaux, B Drevermann, H Forty, RW Frank, M and Greening, TC Hagelberg, R Halley, AW Gianotti, F and Girone, M Hansen, JB Harvey, J Jacobsen, R Hutchcroft, DE Janot, R Jost, B Knobloch, J Kado, M Lehraus, I and Lazeyras, P Maley, R Mato, P May, J Moutussi, A and Pepe-Altarelli, M Ranjard, F Rolandi, L Schlatter, D and Schmitt, B Schneider, O Tejessy, W Teubert, F Tomalin, IR Tournefier, E Veenhof, R Valassi, A Wiedenmann, W and Wright, AE Ajaltouni, Z Badaud, F Chazelle, G Deschamps, O Dessagne, S Falvard, A Ferdi, C Fayolle, D Gay, P and Guicheney, C Henrard, P Jousset, J Michel, B and Monteil, S Montret, JC Pallin, D Pascolo, JM Perret, P and Podlyski, F Bertelsen, H Fernley, T Hansen, JD and Hansen, JR Hansen, PH Kraan, AC Lindahl, A Mollerud, R and Nilsson, BS Rensch, B Waananen, A Daskalakis, G and Kyriakis, A Markou, C Simopoulou, E Siotis, I Vayaki, A and Zachariadou, K Blondel, A Bonneaud, G Brient, JC and Machefert, E Rouge, A Rumpf, M Swynghedauw, M Tanaka, R and Verderi, M Videau, H Ciulli, V Focardi, E Parrini, G and Zachariadou, K Corden, M Georgiopoulos, C Antonelli, A and Antonelli, M Bencivenni, G Bologna, G Bossi, F and Campana, P Capon, G Cerutti, F Chiarella, V Felici, G and Laurelli, P Mannocchi, G Murtas, GP Passalacqua, L and Picchi, P Colrain, P Ten Have, I Hughes, IS Kennedy, J and Knowles, IG Lynch, JG Morton, WT Negus, P O'Shea, V and Raine, C Reeves, P Scarr, JM Smith, K Thompson, AS and Turnbull, RM Wasserbaech, S Buchmuller, O Cavanaugh, R and Dhamotharan, S Geweniger, C Hanke, P Hansper, G and Hepp, V Kluge, EE Putzer, A Sommer, J Stenzel, H and Tittel, K Werner, W Wunsch, M Beuselinck, R Binnie, DM and Cameron, W Davies, G Dornan, PJ Goodsir, S and Marinelli, N Martin, EB Nash, J Nowell, J Rutherford, SA and Sedgbeer, JK Thompson, JC White, R Williams, MD and Ghete, VM Girtler, P Kneringer, E Kuhn, D Rudolph, G and Bouhova-Thacker, E Bowdery, CK Buck, PG Clarke, DP and Ellis, G Finch, AJ Foster, F Hughes, G Jones, RWL and Keemer, NR Pearson, MR Robertson, NA Sloan, T Smizanska, M Snow, SW Williams, MI van der Aa, O Delaere, C and Leibenguth, G Lemaitre, V Bauerdick, LAT Blumenschein, U and van Gemmeren, P Giehl, I Holldorfer, F Jakobs, K and Kasemann, M Kayser, F Kleinknecht, K Muller, AS Quast, G and Renk, B Rohne, E Sander, HG Schmeling, S Wachsmuth, H Wanke, R Zeitnitz, C Ziegler, T Aubert, JJ and Benchouk, C Bonissent, A Carr, J Coyle, P Curtil, C and Ealet, A Etienne, F Fouchez, D Motsch, F Payre, P and Rousseau, D Tilquin, A Talby, M Thulasides, M Aleppo, M and Antonelli, M Ragusa, F Buscher, V David, A Dietl, H and Ganis, G Huttmann, K Lutjens, G Mannert, C Manner, W and Moser, HG Settles, R Seywerd, H Stenzel, H Villegas, M Wiedenmann, W Wolf, G Azzurri, P Boucrot, J and Callot, O Chen, S Cordier, A Davier, M Duflot, L and Grivaz, JF Heusse, P Jacholkowska, A Le Diberder, F and Lefrancois, J Mutz, AM Schune, MH Serin, L Veillet, JJ and Videau, I Zerwas, D Azzurri, P Bagliesi, G and Bettarini, S Boccali, T Bozzi, C Calderini, G Dell'Orso, R Fantechi, R Ferrante, I Fidecaro, F Foa, L and Giammanco, A Giassi, A Gregorio, A Ligabue, F Lusiani, A and Marrocchesi, PS Messineo, A Palla, F Rizzo, G and Sanguinetti, G Sciaba, A Sguazzoni, G Spagnolo, P and Steinberger, J Tenchini, R Venturi, A Vannini, C and Venturi, A Verdini, PG Awunor, O Blair, GA Cowan, G and Garcia-Bellido, A Green, MG Medcalf, T Misiejuk, A and Strong, JA Teixeira-Dias, P Botterill, DR Clifft, RW and Edgecock, TR Edwards, M Haywood, SJ Norton, PR Tomalin, IR Ward, JJ Bloch-Devaux, B Boumediene, D Colas, P and Emery, S Fabbro, B Kozanecki, W Lancon, E Lemaire, MC and Locci, E Perez, P Rander, J Renardy, JF Roussarie, A and Schuller, JP Schwindling, J Tuchming, B Vallage, B and Black, SN Dann, JH Kim, HY Konstantinidis, N Litke, AM and McNeil, MA Taylor, G Booth, CN Cartwright, S and Combley, F Hodgson, PN Lehto, M Thompson, LF and Affholderbach, K Barberio, E Bohrer, A Brandt, S and Burkhardt, H Feigl, E Grupen, C Hess, J Lutters, G and Meinhard, H Minguet-Rodriguez, J Mirabito, L Misiejuk, A and Neugebauer, E Ngac, A Prange, G Rivera, F Saraiva, P and Schafer, U Sieler, U Smolik, L Stephan, F Trier, H and Apollonio, M Borean, C Bosisio, L Della Marina, R and Giannini, G Gobbo, B Musolino, G Pitis, L He, H Kim, H Putz, J Rothberg, J Armstrong, SR Bellantoni, L and Berkelman, K Cinabro, D Conway, JS Cranmer, K Elmer, P and Feng, Z Ferguson, DPS Gao, Y Gonzalez, S Grahl, J and Harton, JL Hayes, OJ Hu, H Jin, S Johnson, RP and Kile, J McNamara, PA Nielsen, J Orejudos, W Pan, Y and Saadi, Y Scott, IJ Sharma, V Walsh, AM Walsh, J and Wear, J von Wimmersperg-Toeller, JH Wiedenmann, W Wu, J and Wu, SL Wu, X Yamartino, JM Zobernig, G Dissertori, G and Abdallah, J Abreu, P Adam, W Adye, T Adzic, P and Ajinenko, I Albrecht, T Alderweireld, T Alekseev, GD and Alemany-Fernandez, R Allmendinger, T Allport, PP Almehed, S and Amaldi, U Amapane, N Amato, S Anashkin, E and Anassontzis, EG Andersson, P Andreazza, A Andringa, S and Anjos, N Antilous, P Apel, WD Arnoud, Y Ask, S and Asman, B Augustin, JE Augustinus, A Baillon, P and Ballestrero, A Bambade, P Barao, F Barbiellini, G and Barbier, R Bardin, D Barker, G Baroncelli, A Battaglia, M Baubillier, M Becks, KH Begalli, M Behrmann, A and Beilliere, P Belokopytov, Y Belous, K Ben-Haim, E and Benekos, N Benvenuti, A Berat, C Berggren, M Berntzon, L and Bertini, D Bertrand, D Besancon, M Besson, N and Bianchi, F Bigi, M Bilenky, MS Bizouard, MA Bloch, D and Blom, M Bluj, M Bonesini, M Bonivento, W Boonekamp, M and Booth, PSL Borgland, AW Borisov, G Bosio, C Botner, O Boudinov, E Bouquet, B Bourdarios, C Bowcock, TJV and Boyko, I Bozovic, I Bozzo, M Bracko, M Branchini, P and Brenke, T Brenner, R Brodet, E Bruckman, P Brunet, JM and Bugge, L Buran, T Burgsmueller, T Buschbeck, B and Buschmann, P Cabrera, S Caccia, M Calvi, M Rozas, AJC and Camporesi, T Canale, V Canepa, M Carena, F Carroll, L Caso, C Gimenez, MVC Castro, N Cattai, A Cavallo, F Cerruti, C Chabaud, V Chapkin, M Charpentier, P and Chaussard, L Checchia, P Chelkov, GA Chen, M Chierici, R and Chliapnikov, R Chochula, P Chorowicz, V Chudoba, J and Chung, SU Cieslik, K Collins, P Colomer, M Contri, R and Cortina, E Cosme, G Cossuti, F Costa, MJ Cowell, JH and Crawley, HB Crennell, D Crepe, S Crosetti, G Cuevas, J and Czellar, S D'Hondt, J Dalmagne, B Dalmau, J and Damgaard, G Davenport, M da Silva, T Da Silva, W and Deghorain, A Della Ricca, G Delpierre, P Demaria, N De Angelis, A De Boer, W de Brabandere, S De Clercq, C De Lotto, B De Maria, N De Min, A de Paula, L Dijkstra, H and Di Ciaccio, L Di Diodato, A Di Simone, A Djannati, A and Dolbeau, J Doroba, K Dracos, M Drees, J Drees, KA and Dris, M Duperrin, A Durand, JD Ehret, R Eigen, G and Ekelof, T Ekspong, G Ellert, M Elsing, M Engel, JP and Erzen, B Santo, MCE Falk, E Fanourakis, G Fassouliotis, D Fayot, J Feindt, M Fenyuk, A Fernandez, J Ferrari, P Ferrer, A Ferrer-Ribas, E Ferro, F Fichet, S and Firestone, A Fischer, PA Flagmeyer, U Foeth, H Fokitis, E Fontanelli, F Franek, B Frodesen, AG Fruhwirth, R and Fulda-Quenzer, F Fuster, J Galloni, A Gamba, D Gamblin, S Gandelman, M Garcia, C Garcia, J Gaspar, C Gaspar, M Gasparini, U Gavillet, P Gazis, E Gele, D Gerber, JP Gerdyukov, L Ghodbane, N Gil, I Glege, F Gokieli, R Golob, B Gomez-Ceballos, G Goncalves, P Caballero, IG and Gopal, G Gorn, L Gorski, M Gouz, Y Gracco, V and Grahl, J Graziani, E Green, C Grefrath, A Grimm, HJ and Gris, P Grosdidier, G Grzelak, K Gunther, M Guy, J and Haag, C Hahn, F Hahn, S Hallgren, A Hamacher, K and Hamilton, K Hansen, J Harris, FJ Haug, S Hauler, F and Hedberg, V Heising, S Hennecke, M Henriques, R and Hernandez, JJ Herquet, P Herr, H Hessing, TL Heuser, JM and Higon, E Hoffman, J Holmgren, SO Holt, PJ and Holthuizen, D Hoorelbeke, S Houlden, MA Hrubec, J Huber, M Huet, K Hughes, GJ Hultqvist, K Jackson, JN and Jacobsson, R Jalocha, P Janik, R Jarlskog, C Jarlskog, G and Jarry, P Jean-Marie, B Jeans, D Johansson, EK and Johansson, PD Jonsson, P Joram, C Juillot, P Jungermann, L Kapusta, F Karafasoulis, K Katsanevas, S Katsoufis, E and Keranen, R Kernel, G Kersevan, BP Kerzel, U and Khomenko, BA Khovanski, NN Kiiskinen, A King, BT Kinvig, A Kjaer, NJ Klapp, O Klein, H Kluit, P Knoblauch, D and Kokkinias, P Konopliannikov, A Koratzinos, M and Kostioukhine, V Kourkoumelis, C Kouznetsov, O Krammer, M and Kreuter, C Kriznic, E Krstic, J Krumstein, Z Kubinec, P and Kucewicz, W Kucharczyk, M Kurowska, J Kurvinen, K and Lamsa, J Lanceri, L Lane, DW Langefeld, P Lapin, V and Laugier, JP Lauhakangas, R Leder, G Ledroit, F Lefebure, V Leinonen, L Leisos, A Leitner, R Lemonne, J and Lenzen, G Lepeltier, V Lesiak, T Lethuillier, M Libby, J and Liebig, W Liko, D Lipniacka, A Lippi, I Loerstad, B and Lokajicek, M Loken, JG Lopes, JH Lopez, JM and Lopez-Femandez, R Loukas, D Lutz, P Lyons, L and MacNaughton, J Mahon, JR Maio, A Malek, A Malmgren, TGM and Maltezos, S Malychev, V Mandl, F Marco, J Marco, R and Marechal, B Margoni, M Marin, JC Mariotti, C Markou, A Martinez-Rivero, C Martinez-Vidal, F Garcia, SMI and Masik, J Mastroyiannopoulos, N Matorras, F Matteuzzi, C and Matthiae, G Mazik, J Mazzucato, F Mazzucato, M McCubbin, M McKay, R McNulty, R Meroni, C Meyer, WT Miagkov, A and Migliore, E Mirabito, L Mitaroff, W Mjoernmark, U and Moa, T Moch, M Moeller, R Moenig, K Monge, R and Montenegro, J Moraes, D Moreau, X Moreno, S Morettini, P and Morton, G Mueller, U Muenich, K Mulders, M and Mulet-Marquis, C Mundim, L Muresan, R Murray, W Muryn, B and Myatt, G Myklebust, T Naraghi, F Nassiakou, M and Navarria, F Navas, S Nawrocki, K Negri, P Neufeld, N and Neumann, W Neumeister, N Nicolaidou, R Nielsen, BS and Nieuwenhuizen, M Niezurawski, P Nikolaenko, V Nikolenko, M and Nomokonov, V Normand, A Nygren, A Oblakowska-Mucha, A and Obraztsov, V Olshevski, A Onofre, A Orava, R Orazi, G Osterberg, K Ouraou, A Oyanguren, A Paganini, P and Paganoni, M Paiano, S Pain, R Paiva, R Palacios, JP and Palka, H Papadopoulou, TD Papageorgiou, K Pape, L and Parkes, C Parodi, F Parzefall, U Passeri, A Passon, O and Pavel, T Pegoraro, M Peralta, L Perepelitsa, V and Pernicka, M Perrotta, A Petridou, C Petrolini, A and Philips, HT Piana, G Piedra, J Pieri, L Pierre, F and Pimenta, M Piotto, E Podobnik, T Poireau, V Pol, ME and Polok, G Polycarpo, E Poropat, P Pozdniakov, V and Privitera, R Pukhaeva, N Pullia, A Radojicic, D Ragazzi, S Rahmani, H Rakoczy, D Rames, J Ramler, L Ratoff, PN Read, A Rebecchi, P Redaelli, NG Regler, M Rehn, J Reid, D Reinhardt, R Renton, P Resvanis, LK and Richard, F Ridky, J Rinaudo, G Ripp-Baudot, I Rivero, M and Rodriguez, D Rohne, O Romero, A Ronchese, P and Rosenberg, EI Rosinsky, P Roudeau, R Rovelli, T Royon, C and Ruhlmann-Kleider, V Ruiz, A Ryabtchikov, D Saarikko, H and Sacquin, Y Sadovsky, A Sajot, G Salmi, L Salt, J and Sampsonidis, D Sannino, M Savoy-Navarro, A Scheidle, T and Schneider, H Schwemling, P Schwering, B Schwickerath, U and Schyns, MAE Scuri, F Seager, P Sedykh, Y Segar, A and Seibert, N Sekulin, R Shellard, RC Sheridan, A Siebel, M and Silvestre, R Simard, L Simonetto, F Sisakian, A and Skaali, TB Smadja, G Smirnov, N Smirnova, O Smith, GR and Sokolov, A Sopczak, A Sosnowski, R Spassov, T and Spiriti, E Sponholz, P Squarcia, S Stampfer, D Stanescu, C Stanic, S Stanitzki, M Stapnes, S Stevenson, K and Stocchi, A Strauss, J Strub, R Stugu, B Szczekowski, M and Szeptycka, M Szumlak, T Tabarelli, T Taffard, AC and Tegenfeldt, F Terranova, F Thomas, J Tilquin, A and Timmermans, J Tinti, N Tkatchev, L Tobin, M Todorov, T and Todorovova, S Toet, DZ Tomaradze, A Tome, B Tonazzo, A Tortora, L Tortosa, P Transtromer, G Travnicek, P and Treille, D Tristram, G Trochimczuk, M Trombini, A and Troncon, C Tsirou, A Turluer, ML Tyapkin, IA Tyapkin, P and Tzamarias, S Ullaland, O Uvarov, V Valenti, G and Vallazza, E Vander Velde, C Van Apeldoorn, GW Van Dam, P and Van den Boeck, W Van Doninck, WK Van Eldik, J Van Lysebetten, A van Remortel, N Van Vulpen, I Vassilopoulos, N and Vegni, G Velos, F Ventura, L Venus, W Verbeure, F and Verdier, P Verlato, M Vertogradov, LS Verzi, V and Vilanova, D Vitale, L Vlasov, E Vodopyanov, AS Vollmer, C Voulgaris, G Vrba, V Wahlen, H Walck, C Washbrook, AJ Weiser, C Wetherell, AM Wicke, D Wickens, J and Wilkinson, G Winter, M Witek, M Wlodek, T Wolf, G and Yi, J Yushchenko, O Zaitsev, A Zalewska, A Zalewski, P and Zavrtanik, D Zevgolatakos, E Zhuravlov, V Zimin, NI and Zintchenko, A Zoller, P Zucchelli, GC Zumerle, G Zupan, M Acciarri, M Achard, P Adriani, O Aguilar-Benitez, M and Alcaraz, J Alemanni, G Allaby, J Aloisio, A Alviggi, MG Ambrosi, G Anderhub, H Andreev, VP Angelescu, T and Anselmo, F Arefiev, A Azemoon, T Aziz, T Bagnaia, P and Bajo, A Baksay, G Baksay, L Balandras, A Baldew, SV and Ball, RC Banerjee, S Banerjee, S Barczyk, A Barillere, R and Barone, L Bartalini, P Basile, M Batalova, N and Battiston, R Bay, A Becattini, F Becker, U Behner, F and Bellucci, L Berbeco, R Berdugo, J Berges, P Bertucci, B and Betev, BL Bhattacharya, S Biasini, M Biglietti, M and Biland, A Blaising, JJ Blyth, SC Bobbink, BJ Bohm, A and Boldizsar, L Borgia, B Bottai, S Bourilkov, D Bourquin, M Braccini, S Branson, JG Brigljevic, V Brochu, F and Brock, IC Buffini, A Buijs, A Burger, JD Burger, WJ and Button, A Cai, XD Campanelli, M Capell, M Romeo, GC and Carlino, G Cartacci, A Casaus, J Castellini, G and Cavallari, E Cavallo, N Cecchi, C Cerrada, M Cesaroni, F and Chamizo, M Chang, YH Chaturvedi, UK Chemarin, M and Chen, A Chen, G Chen, GM Chen, HF Chen, HS Chiefari, G Cifarelli, L Cindolo, F Civinini, C Clare, I and Clare, R Coignet, G Colijn, AP Colino, N Costantini, S and Cotorobai, F Cozzoni, B de la Cruz, B Csilling, A and Cucciarelli, S Dai, TS van Dalen, JA D'Alessandro, R de Asmundis, R Debreczeni, J Deglon, P Degre, P Dehmelt, K and Deiters, K della Volpe, D Delmeire, E Denes, P and DeNotaristefani, F De Salvo, A Diemoz, M Dierckxsens, M and van Dierendonck, D Di Lodovico, F Dionisi, C Dittmar, M and Dominguez, A Doria, A Dova, MT Duchesneau, D Dufournaud, D Duda, M Duinker, P Duran, I Dutta, S Echenard, B and Eline, A El Hage, A El Mamouni, H Engler, A Eppling, FJ Erne, FC Extermann, P Fabre, M Faccini, R and Falagan, MA Falciano, S Favara, A Fay, J Fedin, O and Felcini, M Ferguson, T Ferroni, F Fesefeldt, H and Fiandrini, E Field, JH Filthaut, F Fisher, PH Fisher, W and Fisk, I Forconi, G Fredj, L Freudenreich, K Furetta, C Galaktionov, Y Ganguli, SN Garcia-Abia, P Gataullin, M and Gau, SS Gentile, S Gheordanescu, N Giagu, S Gong, ZF and Grenier, G Grimm, O Gruenewald, MW Guida, M van Gulik, R van Gupta, VK Gurtu, A Gutay, LJ Haas, D and Hasan, A Hatzifotiadou, D Hebbeker, T Herve, A Hidas, P and Hirschfelder, J Hofer, H Hohlmann, M Holzner, G and Hoorani, H Hou, SR Lashvili, I Innocente, V Jin, BN and Jindal, P Jones, LW deJong, P Josa-Mutuberria, I Khan, RA Kaur, M Kienzle-Focacci, MN Kim, D Kim, JK and Kirkby, J Kiss, D Kittel, W Klimentov, A Konig, AC and Koffeman, E Kopal, M Kopp, A Koutsenko, V Kraber, M and Kraemer, RW Krenz, W Kruger, A Kuijten, H Kunin, A and de Guevara, PL Laktineh, I Landi, G Lassila-Perini, K and Lebeau, M Lebedev, A Lebrun, P Lecomte, P Lecoq, P and Le Coultre, P Lee, HJ Le Goff, JM Leiste, R Leonardi, E and Levtchenko, M Levtchenko, P Li, C Likhoded, S Lin, CH Lin, WT Linde, FL Lista, L Liu, ZA Lohmann, W and Longo, E Lu, YS Lu, W Lubelsmeyer, K Luci, C Luckey, D Luminari, L Lugnier, L Lustermann, W Ma, WG Maity, M Malgeri, L Malinin, A Mana, C Mangeol, D Mans, J and Marchesini, P Marian, G Martin, JP Marzano, F and Massaro, GGG Mazumdar, K McNeil, RR Mele, S Merola, L and Merk, M Meschini, M Metzger, WJ von der Mey, M and Mihul, A Milcent, H Mirabelli, G Mnich, J Mohanty, GB and Molnar, P Monteleoni, B Moulik, T Muanza, GS Muheim, F Muijs, AJM Musicar, B Musy, M Nagy, S Natale, S and Napolitano, M Nessi-Tedaldi, F Newman, H Niessen, T and Nisati, A Novak, I Nowak, H Ofierzynski, R Organtini, G and Oulianov, A Pal, I Palomares, C Pandoulas, D and Paoletti, S Paoloni, A Paolucci, P Paramatti, R Park, HK and Park, IH Pascale, G Passaleva, G Patricelli, S Paul, T Pauluzzi, M Paus, C Pauss, F Peach, D Pedace, M and Pensotti, S Perret-Gallix, D Petersen, B Piccolo, D and Pierella, F Pieri, M Pioppi, M Piroue, PA Pistolesi, E and Plyaskin, V Pohl, M Pojidaev, V Postema, H Pothier, J Produit, N Prokofiev, DO Prokofiev, D Quartieri, J and Rahal-Callot, G Rahaman, MA Raics, P Raja, N Ramelli, R and Rancoita, PG Ranieri, R Raspereza, A Razis, P Ren, D and Rescigno, M Reucroft, S van Rhee, T Riemann, S and Riles, K Robohm, A Rodin, J Roe, BP Romero, L Rosca, A Rosemann, C Rosenbleck, C Rosier-Lees, S Roth, S and Rubio, JA Ruggiero, G Ruschmeier, D Rykaczewski, H and Sakharov, A Saremi, S Sarkar, S Salicio, J Sanchez, E and Sanders, MP Sarakinos, ME Schafer, C Schegelsky, V and Schmidt-Kaerst, S Schmitz, D Schopper, H Schotanus, DJ and Schwering, G Sciacca, C Sciarrino, D Seganti, A Servoli, L Shevchenko, S Shivarov, N Shoutko, V Shumilov, E and Shvorob, A Siedenburg, T Son, D Smith, B Souga, C and Spillantini, P Steuer, M Stickland, DP Stone, A Stone, H and Stoyanov, B Straessner, A Sudhakar, K Sultanov, G and Sun, LZ Sushkov, S Suter, H Swain, JD Szillasi, Z and Sztaricskai, T Tang, XW Tarjan, P Tauscher, L Taylor, L and Tellili, B Teyssier, D Timmermans, C Ting, SCC Ting, SM Tonwar, SC Toth, J Tully, C Tung, KL Uchida, Y and Ulbricht, J Uwer, U Valente, E Van de Walle, RT and Vasquez, R Veszpremi, V Vesztergombi, G Vetlitsky, I and Vicinanza, D Viertel, G Villa, S Vivargent, M Vlachos, S and Vodopianov, I Vogel, H Vogt, H Vorobiev, I Vorobyov, AA Vorvolakos, A Wadhwa, M Wallraff, W Wang, Q Wang, XL Wang, ZM Weber, A Weber, M Wienemann, P Wilkens, H Wu, SX Wynhoff, S Xia, L Xu, ZZ Yamamoto, J and Yang, BZ Yang, CG Yang, HJ Yang, M Ye, JB Yeh, SC and You, JM Zalite, A Zalite, Y Zhang, ZP Zhao, J and Zhu, GY Zhu, RY Zhuang, HL Zichichi, A Zilizi, G and Zimmermann, B Zoller, M Abbiendi, G Acton, PD Ainsley, C and Akesson, PF Alexander, G Allison, J Allport, PP and Altekamp, N Amaral, P Ametewee, K Anagnostou, G and Anderson, KJ Anderson, S Arcelli, S Armitage, JC Asai, S and Ashby, SF Ashton, P Astbury, A Axen, D Azuelos, G and Bahan, GA Bailey, I Baines, JTM Ball, AH Banks, J and Barberio, E Barillari, T Barker, GJ Barlow, RJ and Barnett, S Bartoldus, R Batley, RJ Beaudoin, G Bechtle, P Bechtluft, J Beck, A Becker, J Beeston, C Behnke, T Bell, AN Bell, KW Bell, PJ Bella, G Bellerive, A and Benelli, G Bentvelsen, S Berlich, P Bethke, S and Biebel, O Binder, U Blobel, V Bloodworth, IJ Bloomer, JE and Bock, P Boden, B Bohme, J Boeriu, O Bonacorsi, D and Bosch, HM Bougerolle, S Bouterneur, M Bouwens, BT and Brabson, BB Braibant, S Breuker, H Bright-Thomas, P and Brigliadori, L Brown, RM Brun, R Burgin, R Buesser, K and Buijs, A Burckhart, HJ Burgard, C Cammin, J Campana, S Capiluppi, P Carnegie, RK Caron, B Carter, AA and Carter, JR Chang, CY Charlesworth, C Charlton, DG Chrin, JTM Chrisman, D Chu, SL Ciocca, C Clarke, PEL Clay, E Clayton, JC Cohen, I Collins, WJ Conboy, JE Cooke, OC Cooper, M Couch, M Couchman, J Coupland, M Silva, ED Coxe, RL Csilling, A Cuffiani, M Dado, S and Dallapiccola, C Dallavalle, GM Dallison, S Darling, C De Jong, S De Roeck, A De Wolf, EA Debu, P Deng, H and Deninno, MM Dervan, P Desch, K Dieckmann, A Dienes, B and Dittmar, M Dixit, MS Donkers, M Doucet, M Dubbert, J and Duboscq, JE Duchovni, E Duckeck, G Duerdoth, IP and Dumas, DJP Eckerlin, G Edwards, JEG Elcombe, PA and Estabrooks, PG Etzion, E Evans, HG Evans, M Fabbri, F and Fanti, M Fath, P Feld, L Ferrari, P Fiedler, F and Fierro, M Fincke-Keeler, M Fischer, HM Fleck, I Folman, R Fong, DG Ford, M Foucher, M Frey, A Furtjes, A and Fukui, H Fukunaga, C Futyan, DI Gagnon, P Gaidot, A and Ganel, O Gary, JW Gascon, J Gascon-Shotkin, SM Gaycken, G Geddes, NI Geich-Gimbel, C Gensler, SW Gentit, FX and Geralis, T Giacomelli, G Giacomelli, P Giacomelli, R and Gibson, V Gibson, WR Gillies, JD Gingrich, DM Giunta, M and Glenzinski, D Goldberg, J Goodrick, MJ Gorn, W and Graham, K Grandi, C Grant, FC Gross, E Grunhaus, J and Gruwe, M Gunther, PO Gupta, A Hagemann, J Hajdu, C and Hamann, M Hanson, GG Hansroul, M Hapke, M Harder, K and Harel, A Hargrovet, CK Harin-Dirac, M Harrison, PF Hart, PA Hartmann, C Hattersley, PM Hauschild, M Hawkes, CM and Hawkings, R Heflin, E Hemingway, RJ Hensel, C and Herten, G Heuer, RD Hildreth, MD Hill, JC Hillier, SJ and Hilse, T Hinshaw, DA Ho, C Hoare, J Hobbs, JD and Hobson, PR Hochman, D Hocker, A Hoffman, K Holl, B and Homer, RJ Honma, AK Horvath, D Hossain, KR Hou, SR and Howard, R Howarth, CP Huntemeyer, P Hughes-Jones, RE and Humbert, R Hutchcroft, DE Igo-Kemenes, P Ihssen, H and Imrie, DC Ingram, M Ishii, K Jacob, FR Janissen, AC and Jawahery, A Jeffreys, PW Jeremie, H Jimack, M Jobes, M and Joly, T Jones, CR Jones, G Jones, M Jones, RWL and Jost, U Jovanovic, P Jui, C Jobes, M Joly, A Jones, CR Jones, G Jones, M Jones, RWL Jost, U Jovanovic, P and Jui, C Junk, TR Kanaya, N Kanzaki, J Karapetian, G and Karlen, D Kartvelishvili, V Kawagoe, K Kawamoto, T and Keeler, RK Kellogg, RG Kennedy, BW Kim, DH King, BJ and Kirk, J Klein, K Kleinwort, C Klem, DE Klier, A and Kluth, S Kobayashi, T Kobel, M Kopke, L Koetke, DS and Kokott, TP Komamiya, S Kormos, L Kowalewski, R Kramer, T and Kral, JF Kress, T Kreutzmann, H Krieger, P von Krogh, J Kroll, J Krop, D Kruger, K Kuhl, T Kupper, M Kuwano, M Kyberd, P Lafferty, GD Lafoux, H and Lahmann, R Lai, WP Lamarche, F Landsman, H Lanske, D and Larson, WJ Lauber, J Lautenschlager, SR Lawson, I and Layter, JG Lazic, D Le Du, P Leblanc, P Lee, AM and Lefebvre, E Lehto, MH Leins, A Lellouch, D Lennert, P and Leroy, C Lessard, L Letts, J Levegrun, S Levinson, L and Lewis, C Liebisch, R Lillich, J Littlewood, C Lloyd, AW Lloyd, SL Loebinger, FK Long, GD Lorah, JM and Lorazo, B Losty, MJ Lou, XC Lu, J Ludwig, A Ludwig, J Luig, A Macchiolo, A Macpherson, A Mader, W and Mattig, P Malik, A Mannelli, M Marcellini, S Marchant, TE Maringer, G Markus, C Martin, A Martin, JP and Martinez, G Masetti, G Mashimo, T Matthews, W Maur, U and McDonald, WJ McGowan, RF McKenna, J Mckigney, EA and McMahon, TJ McNab, AI McNutt, J McPherson, AC McPherson, RA Meijers, F Mendez-Lorenzo, P Menges, W Menke, S and Menszner, D Merritt, FS Mes, H Meyer, J Meyer, N and Michelini, A Middleton, RP Mihara, S Mikenberg, G and Mildenberger, J Miller, DJ Milstene, C Mir, R Moed, S and Mohr, W Moisan, C Montanari, A Mori, T Morii, M and Moss, MW Mouthuy, T Muller, U Murphy, PG Mutter, A and Nagai, K Nakamura, I Nanjo, H Neal, HA Nellen, B and Nguyen, HH Nijjhar, B Nisius, R Nozaki, M Oakham, FG and Odorici, F Ogg, M Ogren, HO Oh, A Oh, H Okpara, A and Oldershaw, NJ Omori, T O'Neale, SW O'Neill, BP Oram, CJ Oreglia, MJ Orito, S Pahl, C Palinkas, J and Palmonari, F Pansart, JP Panzer-Steindel, B Paschievici, P and Pasztor, G Pater, JR Patrick, GN Pawley, SJ and Paz-Jaoshvili, N Pearce, MJ Petzold, S Pfeifenschneider, P and Pfister, P Pilcher, JE Pinfold, J Pitman, D Plane, DE Poffenberger, P Poli, B Polok, J Pooth, O and Posthaus, A Pouladdej, A del Poz, LA Prebys, E and Pritchard, TW Przybycien, M Przysiezniak, H Quadt, A and Quast, G Rabbertz, K Raith, B Redmond, MW Rees, DL and Rembser, C Renkel, P Richards, GE Rick, H Rigby, D and Riles, K Robins, SA Robinson, D Rodning, N Rollnik, A and Roney, JM Rooke, A Ros, E Rosati, S Roscoe, K and Rossberg, S Rossi, AM Rosvick, M Routenburg, P Rozen, Y and Runge, K Runolfsson, O Ruppel, U Rust, DR Rylko, R and Sachs, K Saeki, T Sahr, O Sanghera, S Sarkisyan, EKG and Sasaki, M Sbarra, C Schaile, AD Schaile, O and Schappert, W Scharf, F Scharff-Hansen, P Schenk, P and Schieck, J Schmitt, B von der Schmitt, H Schmitt, S and Schorner-Sadenius, T Schreiber, S Schroder, M Schutz, P and Schultz-Coulon, HC Schulz, M Schumacher, M Schwarz, J and Schwick, C Schwiening, J Scott, WG Settles, M Seuster, R and Shears, TG Shen, BC Shepherd-Themistocleous, CH and Sherwood, P Shypit, R Simon, A Singh, P Siroli, GP and Sittler, A Skillman, A Skuja, A Smith, AM Smith, TJ and Snow, GA Sobie, R Soldner-Rembold, S Spagnolo, S Spano, F Springer, RW Sproston, M Stahl, A Starks, M and Steiert, M Stephens, K Steuerer, J Stier, HE and Stockhausen, B Stoll, K Strohmer, R Strom, D Strumia, F and Stumpf, L Surrow, B Szymanski, P Tafirout, R Takeda, H Takeshita, T Talbot, SD Tanaka, S Taras, P Tarem, S Tasevsky, M Taylor, RJ Tecchio, M Teixeira-Dias, P and Tesch, N Teuscher, R Thackray, NJ Thiergen, M Thomas, J and Thomson, MA von Torne, E Torrence, E Towers, S Toya, D Trocsanyi, Z Tran, P Transtromer, G Trefzger, T and Tresilian, NJ Trigger, I Tscheulin, M Tsukamoto, T Tsur, E Turcot, AS Tumer-Watson, MF Tysarczyk-Niemeyer, G and Ueda, I Ujvari, B Utzat, P Vachon, B Van den Plas, D and Van Kooten, R VanDalen, GJ Vannerem, P Vasseur, G and Vertesi, R Verzocchi, M Vikas, P Vincter, M Virtue, CJ and Vokurka, EH Vollmer, CF Voss, H Vossebeld, J and Wackerle, F Wagner, A Wagner, DL Wahl, C Walker, JP and Waller, D Ward, CP Ward, DR Ward, JJ Watkins, PM and Watson, AT Watson, NK Weber, M Weber, P Weisz, S and Wels, PS Wengler, T Wermes, N Wetterling, D Weymann, M and Whalley, MA White, JS Wilkens, B Wilson, JA Wilson, GW Wingerter, I Winterer, VH Wlodek, T Wolf, G Wood, NC Wotton, S Wyatt, TR Yaari, R Yamashita, S Yang, Y and Yeaman, A Yekutieli, G Yurko, M Zacek, V Zacharov, I and Zer-Zion, D Zeuner, W Zivkovic, L Zorn, GT Abe, K and Abe, K Abe, T Abt, I Acton, PD Adam, I Agnew, G and Akagi, T Akimoto, H Allen, NJ Ash, WW Aston, D and Bacchetta, N Baird, KG Baltay, C Band, HR Barakat, MB and Baranko, GJ Bardon, O Barklow, TL Bashindzhagian, GL and Battiston, R Bauer, JM Bazarko, AO Bean, A Bellodi, G and Ben-David, R Benvenuti, AC Berger, R Biasini, M and Bienz, T Bilei, GM Bisello, D Blaylock, G Bogart, J and Bolen, B Bolton, T Bower, GR Brau, JE Breidenbach, M and Bugg, WM Burke, D Burnett, TH Burrows, PN Busza, W and Calcaterra, A Caldwell, DO Camanzi, B Carpinelli, M and Carr, J Cassell, R Castaldi, R Castro, A Cavalli-Sforza, M Chadwick, GB Chou, A Church, E Claus, R Cohn, HO and Coller, JA Convery, MR Cook, V Cotton, R Cowan, RF and Coyle, PA Coyne, DG Crawford, G D'Oliveira, A and Damerell, CJS Daoudi, M Dasu, S de Groot, N de Sangro, R and De Simone, P De Simone, S Dell'Orso, R Dervan, PJ and Dima, M Dong, DN Doser, M Du, PYC Dubois, R Duboscq, JE Eigen, G Eisenstein, BI Elia, R Erdos, E and Erofeeva, I Eschenburg, V Etzion, E Fahey, S Falciai, D and Fan, C Fernandez, JP Fero, MJ Flood, K Frey, R and Friedman, JI Furuno, K Garwin, EL Gillman, T Gladding, G and Gonzalez, S Hallewell, GD Hart, EL Harton, JL Hasan, A Hasegawa, Y Hasuko, K Hedges, S Hertzbach, SS and Hildreth, MD Hitlin, DG Honma, A Huber, JS Huffer, ME and Hughes, EW Huynh, X Hwang, H Iwasaki, M Iwasaki, Y and Izen, JM Jackson, DJ Jacques, P Jaros, JA Jiang, ZY and Johnson, AS Johnson, JR Johnson, RA Junk, T and Kajikawa, R Kalelkar, M Kamyshkov, YA Kang, HJ Karliner, I Kawahara, H Kelsey, MH Kendall, HW Kim, YD King, M and King, R Kofler, R Krishna, NM Kwon, Y Labs, JF and Kroeger, RS Langston, M Lath, A Lauber, JA Leith, DWG and Lia, V Lin, C Liu, MX Loreti, M Lu, A Lynch, HL and Ma, J Mancinelli, G Manly, S Mantovani, G and Markiewicz, TW Maruyama, T Masuda, H Mazzucato, H and McGowan, JF McKemey, AK Meadows, BT Messner, R Mockett, PM Moffeit, KC Moore, TB Morii, M Mours, B Muller, D and Mueller, G Murzin, V Nagamine, T Narita, S and Nauenberg, U Neal, H Nesom, G Nussbaum, M Ohnishi, Y and Oishi, N Onoprienko, D Osborne, LS Panvini, RS Park, CH and Park, H Pavel, TJ Peruzzi, I Pescara, L Piccolo, M and Piemontese, L Pieroni, E Pitts, KT Plano, RJ and Prepost, R Prescott, CY Punkar, G Quigley, J Ratcliff, BN Reeves, K Reeves, TW Reidy, J Reinertsen, PL and Rensing, PE Rochester, LS Rothberg, JE Rowson, PC and Russell, JJ Saxton, OH Schalk, T Schindler, RH and Schneekloth, U Schumm, BA Schwiening, J Seiden, A Sen, S and Serbo, VV Servoli, L Shaevitz, MH Shank, JT Shapiro, G Sherden, DJ Shmakov, KD Simopoulos, C Sinev, NB and Smith, SR Smy, MB Snyder, JA Sokoloff, MD Staengle, H and Stahl, A Starner, P Steiner, H Steiner, R Strauss, MG Su, D Suekane, F Sugiyama, A Suzuki, A Suzuki, S and Swartz, M Szumilo, A Takahashi, T Taylor, FE Thaler, JJ Thom, J Torrence, E Trandafir, AI Turk, JD Usher, T Va'vra, J Vannini, C Vella, E Venuti, JP Verdier, R Verdini, PG Wagner, DL Wagner, SR Waite, AP and Walston, S Wang, J Watts, SJ Weidemann, AW Weiss, ER and Whitaker, JS White, SL Wickens, FJ Williams, DA and Williams, DC Williams, SH Willocq, S Wilson, RJ and Wisniewski, WJ Wittlin, JL Woods, M Word, GB Wright, TR and Wyss, J Yamamoto, RK Yamartino, JM Yang, XQ Yashima, J Yellin, SJ Young, CC Yuta, H Zapalac, G Zdarko, RW and Zeitlin, C Zhou, J ALEPH Collaborat DELPHI Collaborat and L3 Collaborat OPAL Collaborat SLD Collaborat

Subjects
High Energy Physics::Phenomenology, High Energy Physics::Experiment
Abstract

We report on the final electroweak measurements performed with data taken at the Z resonance by the experiments operating at the electron-positron colliders SLC and LEP. The data consist of 17 million Z decays accumulated by the ALEPH, DELPHI, L3 and OPAL experiments at LEP, and 600 thousand Z decays by the SLID experiment using a polarised beam at SLC. The measurements include cross-sections, forward-backward asymmetries and polarised asymmetries. The mass and width of the Z boson, m(Z) and Gamma(Z), and its couplings to fermions, for example the p parameter and the effective electroweak mixing angle for leptons, are precisely measured: m(Z) = 91.1875 +/- 0.0021 GeV, Gamma(Z) = 2.4952 +/- 0.0023 GeV, rho(l) = 1.0050 +/- 0.0010, sin(2)theta(eff)(lept) = 0.23153 +/- 0.00016. The number of light neutrino species is determined to be 2.9840 +/- 0.0082, in agreement with the three observed generations of fundamental fermions. The results are compared to the predictions of the Standard Model (SM). At the Z-pole, electroweak radiative corrections beyond the running of the QED and QCD coupling constants are observed with a significance of five standard deviations, and in agreement with the Standard Model. Of the many Z-pole measurements, the forward-backward asymmetry in b-quark production shows the largest difference with respect to its SM expectation, at the level of 2.8 standard deviations. Through radiative corrections evaluated in the framework of the Standard Model, the Z-pole data are also used to predict the mass of the top quark, m(t) = 173(+10)(+13) GeV, and the mass of the W boson, m(W) = 80.363 +/- 0.032 GeV. These indirect constraints are compared to the direct measurements, providing a stringent test of the SM. Using in addition the direct measurements of m(t) and m(W), the mass of the as yet unobserved SM Higgs boson is predicted with a relative uncertainty of about 50% and found to be less than 285 GeV at 95% confidence level. (c) 2006 Elsevier B.V. All rights reserved.

Published
2006

21. [Total splenectomy for a recurrent giant splenic cyst]

Author

M, Casaccia, L, Saltalamacchia, F, Panaro, D, Cavaliere, D, Ghinolfi, S, Di Domenico, A, Savelli, and U, Valente

Subjects
Adult, Cysts, Splenectomy, Humans, Female, Splenic Diseases
Abstract

Primary splenic cysts are a rare finding. Some are large and require surgical removal. The Authors report a case of a recurrent huge splenic cyst in a 41-year-old female patient. A marsupialization was performed at another hospital 6 years before. Ultrasonography and computed tomography imaging revealed a cystic lesion in the spleen measuring approximately 20 cm in diameter. A total open splenectomy was performed. Postoperative course was uneventful. The histologic diagnosis was an epithelial cyst of the spleen with no atypical cells in the cyst wall, as previously found at the first operation. The epidermoid cysts have an epidermal lining, and prevention of recurrence is dependent on complete resection of the cyst wall preserving, whenever possible, the splenic tissue. Recurrence can be avoided with partial splenectomy in polar localization of the cyst, or complete removal of the cyst by "peeling" it off the splenic parenchyma. Marsupialization of the cyst, either via a laparoscopic or an open approach, is often ineffective.

Published
2005

22. [Cystic lymphangioma of the adult: our experience and review of literature]

Author

D, Cavaliere, D, Ghinolfi, G V, Tommasi, F, Panaro, S, Di Domenico, M, Miggino, S, Dallatomasina, B, Troilo, I, Nardi, L, Chessa, and U, Valente

Subjects
Adult, Male, Head and Neck Neoplasms, Age Factors, Humans, Female, Radiography, Thoracic, Lymphangioma, Cystic, Middle Aged, Tomography, X-Ray Computed
Abstract

Cystic lymphangioma is an uncommon benign pathology, usually reported in children, rarely in adult. Its embryopathogenesis is still controversial: it seems to arise from the lymphatic vessels, mainly in the cervico-cranial district. It is macroscopically characterised by multiple cystic non-communicating concamerations. Definitive diagnosis used to be intraoperative and was usually an unexpected finding. Nowadays, with modern imaging technologies, CT and MRI, diagnosis can be assumed before intervention even though certain diagnosis can still be reached only with histological examination. Imaging techniques can help for a precise mapping of the lesion and definition of its limits with the other structures, improving therapeutic success. Various therapeutical options are reported in literature, but complete surgical excision is still considered the best approach and the most successful. The Authors report their experience and review the literature on cystic lymphangioma in adult.

Published
2004

23. Laparoscopic physiological hiatoplasty for hiatal hernia: new composite 'A'-shaped mesh. Physical and geometrical analysis and preliminary clinical results

Author

M, Casaccia, P, Torelli, F, Panaro, D, Cavaliere, A, Ventura, and U, Valente

Subjects
Adult, Male, Diaphragm, Reproducibility of Results, Prostheses and Implants, Middle Aged, Models, Theoretical, Surgical Mesh, Hernia, Hiatal, Implants, Experimental, Recurrence, Cadaver, Humans, Female, Laparoscopy, Polytetrafluoroethylene, Aged, Follow-Up Studies
Abstract

We analyzed, using a theoretical model, the modality of recurrence after a simple cruroplasty for large hiatal hernias, and on the basis of physical and geometrical principles, we conceived a new shaped mesh for a "tension-free" repair.We performed a physical and geometrical analysis of the hiatal region on a theoretical model. We also performed an anatomic study on 20 fresh cadavers to verify the reproducibility of the theoretical model and to study the most suitable shape for mesh and its adaptability to the hiatal region. Between September 2000 and October 2001, eight patients received laparoscopic reparation of large (type II or III) hiatal hernias by means of a composite "A"-shaped polytetrafluoroethylene (PTFE)-polypropylene mesh. There were two men and six women; mean age was 65 years (range, 35-78 years). Concomitant esophagitis was found in five patients and impaired esophageal peristalsis in two patients. A total or a partial fundoplication was associated in these cases.The physical and geometrical analysis of the hiatal region explained the reasons for the recurrence after hiatoplasty. The anatomical study on fresh cadavers resulted in a mesh tailored in an "A" shape and permitted to verify the adaptability of such a shaped mesh composed of two layers, polypropylene and PTFE. In the clinical series no conversions occurred; the mortality rate was null. Persistent dysphagia was present in two patients and disappeared after 3 months of treatment. No recurrence was observed at an 8-month average follow-up.The preliminary clinical study confirms the feasibility of this tension-free repair and the effectiveness of this composite A-shaped mesh.

Published
2002

24. [The national program of pediatric transplantation]

Author

G, Frustagli, P, Chistolini, V, Macellari, D A, Mattucci, A, Sargentini, and U, Valente

Subjects
Adult, Italy, Waiting Lists, Humans, Organ Transplantation, Child, Program Evaluation
Abstract

The national programme for paediatric transplants currently implemented at the Istituto Superiore di Sanità is one of the first results of the efforts devoted to the definition of an efficient co-ordination policy of the transplantation activity in Italy. Since 1997 the programme has allowed all transplant centres throughout Italy to share unified waiting lists for kidney, heart, lung and liver, which gives paediatric patients a much better possibility than with local waiting lists. We present the regulations, criteria and operative solutions adopted to make the programme work, and the analysis of the data collected in these three years. The analysis gives statistical information on the composition and evolution of waiting lists and transplants done, which may be useful in the continuous process of revision and improvement of the criteria for recipient selection.

Published
2001

25. Split liver transplantation: need for arterial reconstruction in adult patients

Author

R Mondello, A. Antonucci, G Bottino, F Ravazzoni, A Genzone, N Morelli, E Andorno, and U. Valente

Subjects
Adult, medicine.medical_specialty, Split Liver Transplantation, Humans, Liver Transplantation, Arterial reconstruction, Surgical anastomosis, Text mining, Hepatic Artery, Postoperative Complications, medicine, Cadaver, Transplantation, Adult patients, business.industry, Thrombosis, Surgery, medicine.anatomical_structure, Liver, Split liver transplantation, Circulatory system, Tissue and Organ Harvesting, business, Blood vessel
Published
2001

26. Split liver transplantation in adult patients: hepatic and portal vein division and reconstruction

Author

N Morelli, A. Antonucci, A Genzone, U. Valente, F Ravazzoni, R Mondello, G Bottino, and E Andorno

Subjects
Adult, medicine.medical_specialty, medicine.medical_treatment, Split Liver Transplantation, Portal vein, Anastomosis, Liver transplantation, Hepatic Veins, Surgical anastomosis, SLT, Medicine, Humans, Liver Transplantation, Hepatic Vein, Portal Vein, Reconstruction, Transplantation, Adult patients, business.industry, Anastomosis, Surgical, Surgery, medicine.anatomical_structure, Split liver transplantation, Tissue and Organ Harvesting, business, Blood vessel
Published
2001

27. Tauroursodeoxycholic acid administration as adjuvant therapy in cirrhotic patients on transplantation waiting lists

Author

S, Caglieris, E, Giannini, G, Dardano, L, Mondello, U, Valente, and R, Testa

Subjects
Liver Cirrhosis, Male, Taurochenodeoxycholic Acid, Cholagogues and Choleretics, Treatment Outcome, Liver Function Tests, Waiting Lists, Chemotherapy, Adjuvant, Case-Control Studies, Humans, Female, Middle Aged, Liver Transplantation
Abstract

The lack of organ availability and an increased number of end-stage cirrhotic patients has led to the lengthening of liver transplantation waiting lists. The progressive worsening of clinical and functional performance in patients awaiting the graft is one of the factors implicated in the increased mortality during the wait and in poor transplantation outcome. In this work our aim was to evaluate the effects of tauroursodeoxycholic acid administration on biochemical, clinical and functional parameters in a group of cirrhotic patients consecutively placed onto our liver transplantation waiting list.Ten cirrhotic patients underwent biochemical, clinical and functional evaluation at the time of entering on our liver transplantation waiting list, then tauroursodeoxycholic acid was administered until liver transplantation. Complete evaluation was repeated every 2 months. The results were compared to those of a comparable historical control group that had undergone liver transplantation the year before the study.All patients were transplanted within 6 months from insertion on the waiting list. Longitudinal analysis of the treated group showed that cholestasis and cytolisis parameters constantly decreased and that gamma-glutamyl transpeptidase was significantly lower compared to baseline values at the 4th month of therapy. Clinical and functional parameters remained stable during follow-up. Comparison with the control group showed that gamma-glutamyl transpeptidase, alkaline phosphatase and both aminotransferases were reduced at the 4th month of therapy. Fewer days of hospital stay and less intensive care were required in the treated group.Treatment of end-stage cirrhotic patients awaiting liver transplantation with tauroursodeoxycholic acid improves biochemical parameters of cytolisis and cholestasis, and furthermore helps to maintain clinical and functional stability during the wait. Improved biochemical conditions and steady clinical-functional performance may promote better short-term transplant outcome.

Published
2000

28. De novo cancers in paediatric renal transplant recipients: a multicentre analysis within the North Italy Transplant programme (NITp), Italy

Author

G. F. Zanon, M. Scalamogna, Luisa Berardinelli, M. Cardillo, A. Nocera, U. Valente, Luciana Ghio, Graziella Zacchello, I. Fontana, Roberto Dall'Amico, and F. Ginevri

Subjects
Male, Pediatric Patients, Cancer Research, medicine.medical_specialty, Adolescent, medicine.medical_treatment, Humans, Kidney, Kidney Transplantation, Cancer, North Italy Transplant, NITp, Immunosuppression, Lymphoproliferative disorders, Cohort Studies, Postoperative Complications, Risk Factors, hemic and lymphatic diseases, Internal medicine, Neoplasms, medicine, Dysgerminoma, Child, Kidney transplantation, business.industry, Infant, medicine.disease, Surgery, Transplantation, surgical procedures, operative, Oncology, Italy, Child, Preschool, Female, Complication, business, Kidney disease
Abstract

The purpose of this study was to determine the frequency and the outcome of de novo malignancies in a cohort of renal transplant paediatric patients. The records of 493 kidney transplants, carried out in 454 paediatric recipients at the three paediatric transplant centres of the North Italy Transplant programme (NITp, Italy) were reviewed. 10 cases of malignancies (2.2%) comprising both PTLD (post-transplant lymphoproliferative disorders) (6 cases, 1.3%) and non-PTLD malignancies (4 cases, 0.88%) were reported. Non-PTLD included one urothelial carcinoma and one Wilms' tumour of the recipient's left native kidney, one abdominal dysgerminoma and one optic nerve glioma of the left eye. The PTLD consisted of localised or disseminated Epstein–Barr virus (EBV)—associated B-lymphocyte monoclonal (5 cases) and polyclonal (1 case) proliferations. All patients suffering from PTLD had been EBV-negative at the time of transplantion, but developed EBV primary infection after transplantion. All PTLD patient donors were EBV-positive. In addition, all but 1 patient received, before and/or after transplantation, a range of immunosuppressive drugs in addition to the baseline prophylactic immunosuppressive regimen. Moreover, 3 patients suffered from syndromes associated with a genetic predisposition to cancer. Finally, the malignancies reported here were associated with 20% graft failure and 20% mortality rates.

Published
2000

29. Effects of ischemia-reperfusion on hepatic glutathione and plasmatic markers of graft function during in situ split-liver transplantation in adult recipients

Author

G, Santori, E, Andorno, I, Fontana, D, Cottalasso, and U, Valente

Subjects
Adult, Male, Hepatic Glutathione, Split Liver Transplantation, Organ Preservation, Middle Aged, Prognosis, Glutathione, Tissue Donors, Liver Transplantation, Italy, Liver Function Tests, Humans, SLT, Liver, Ischemia, Reperfusion, GSH, HPLC, Reperfusion Injury, Hepatectomy, Female
Abstract

In situ split-liver transplantation is a new surgical technique where the bipartition of a single liver allows procurement of a right graft (segments I, IV, V-VIII) for an adult recipient (75% of the total liver volume), and a left graft (segments II and III) for a child recipient. The present study was designed to assess the effects of ischemia-reperfusion on right grafts obtained by in situ split-liver transplantation. To this aim, hepatic glutathione and conventional plasmatic markers of allograft function (alanine and aspartate aminotransferase, total bilirubin, prothrombin time, lactate dehydrogenase, gamma-glutamyltranspeptidase, and alkaline phosphatase) were evaluated in four adult recipients. At the time of reperfusion, a marked glutathione decrease was found in the segment VI in three cases, whereas the amount of glutathione in segment IV was related to the duration of cold ischemia in all cases. Upon reperfusion, a marked increase in plasmatic alanine aminotransferase, aspartate aminotransferase, and lactate dehydrogenase was found. A recovery in prothrombin time was observed from the first day in three cases. An increasing trend in total bilirubin, gamma-glutamyltranspeptidase, and alkaline phosphatase was noted from the second day after transplant. This preliminary study suggests a possible relationship between the duration of cold ischemia, amount of glutathione in segment IV of the right graft, and the trend in plasmatic markers of allograft damage during in situ split-liver transplantation in adult recipients.

Published
2000

30. [Jejunal adenocarcinoma: case report and review of the literature]

Author

G V, Tommasi, G, Dardano, A, Antonucci, A, Carisetto, M, Pittaluga, F, Panaro, L, Saltalamacchia, M T, Nobile, and U, Valente

Subjects
Male, Jejunal Neoplasms, Humans, Adenocarcinoma, Middle Aged
Abstract

Adenocarcinoma of the jejunum is a rare tumor. The diagnosis is often difficult and not early. The Authors report a case recently observed in their clinical practice and successfully operated, reporting also what's in the literature about.

Published
1999

31. Correlation between angiotensin-converting enzyme gene insertion/deletion polymorphism and kidney graft long-term outcome in pediatric recipients: a single-center analysis

Author

S, Barocci, F, Ginevri, U, Valente, F, Torre, R, Gusmano, and A, Nocera

Subjects
Male, Renin-Angiotensin System, Polymorphism, Genetic, Adolescent, Genotype, Angiotensin II, Child, Preschool, Humans, Angiotensin-Converting Enzyme Inhibitors, Female, Peptidyl-Dipeptidase A, Child, Kidney Transplantation
Abstract

Despite numerous advances in the areas of organ preservation, histocompatibility, and immunosuppression, chronic deterioration of organ allograft function, referred to as "chronic rejection," still remains the main obstacle to long-term graft survival. The common feature of chronic rejection is a concentric generalized graft arteriosclerosis associated with interstitial fibrosis that reflects an allogeneic injury to graft arteries, possibly worsened by other alloantigen-independent risk factors. The presence of the angiotensin I-converting enzyme (ACE) gene-deleted (D) allele has been associated, when in homozygosity, with increased risk of cardiovascular diseases and with an accelerated progression of organ damage in a variety of kidney diseases. In this study, we analyzed whether the insertion/deletion polymorphism of the ACE gene, because of its negative prognostic impact on cardiovascular and renal pathology, could have any influence on kidney graft survival in pediatric recipients.DNA was isolated from peripheral blood mononuclear cells from 146 pediatric dialysis patients (mean age: 12.9 years) who received a first kidney graft at our center between December 1985 and July 1997. To rule out any bias due to acute graft losses, only 119 patients who reached a minimum of 12 months of graft survival were considered for statistical analysis. The insertion/deletion polymorphism of the ACE gene was detected using a polymerase chain reaction technique with two flanking primers.The results demonstrated that (i) the distribution of DD and non-DD (ID + II) genotypes was 36.1% (43 patients) and 63.8% (76 patients), respectively; (ii) actuarial graft survival at 7, 8, 9, and 10 years in patients with non-DD genotype was significantly higher than that in patients with DD genotype (7 years: 94.6% vs. 72.4%, P0.05; 8 years: 94.6% vs. 62%, P0.025; 9 years: 87.3% vs. 51.4%, P0.025; 10 years: 76.3% vs. 25.7%, P0.01).In conclusion, the above data indicate that DD genotype is associated in pediatric kidney graft recipients with a shorter long-term kidney graft survival and suggest a possible role of this genotype as a cofactor in the progression of nonimmunological injuries leading to chronic kidney graft failure.

Published
1999

32. Cytomegalovirus infection is a trigger for monoclonal immunoglobulins in paediatric kidney transplant recipients

Author

S Mangraviti, U. Valente, Fabrizio Ginevri, G Rossi, A. Nocera, G. Losurdo, G. Basile, L Bonato, A. M. Rabagliati, I Fontana, S Barocci, and Rosanna Gusmano

Subjects
Human cytomegalovirus, Male, Time Factors, Adolescent, Paraproteinemias, Immunoglobulins, medicine.disease_cause, Antiviral Agents, Herpesviridae, Virus, Postoperative Complications, Betaherpesvirinae, medicine, Humans, Risk factor, Child, Ganciclovir, Retrospective Studies, Transplantation, Kidney, biology, Antibodies, Monoclonal, biology.organism_classification, medicine.disease, Virology, Kidney Transplantation, medicine.anatomical_structure, Immunoglobulin M, Immunoglobulin G, Immunology, Cytomegalovirus Infections, Surgery, Female, Viral disease, Follow-Up Studies
Published
1998

33. [Retrorectal hamartomatous cysts or 'tail gut syndrome': a case report and review of the literature]

Author

G V, Tommasi, V, Arcuri, P, Ceppa, F, Ermili, V, Casolino, C, Bottino, A, Carisetto, C, Biancardi, F, Dondero, G, Paraluppi, and U, Valente

Subjects
Diagnosis, Differential, Male, Biopsy, Hamartoma, Buttocks, Humans, Middle Aged
Abstract

Retrorectal cyst hamartomas or so called tail gut syndrome are dystopic lesions, rarely reported in Literature, characterized by the presence of cysts lined by mucous-producing ciliated epithelium. The Authors report a case, recently observed and surgically treated, in a 55 year old male, hospitalized because of an abscess and fistula in the right buttock diagnosed to be a cyst hamartoma. The Literature is reviewed as well.

Published
1998

34. [Severe infections after orthotopic hepatic transplant]

Author

M R, Germi, R, Pellicci, C, Viscoli, G, Ardizzone, D, Dodi, M, Bertocchi, C, Siani, U, Valente, and D, Civalleri

Subjects
Adult, Male, Infection Control, Humans, Female, Bacterial Infections, Middle Aged, Infections, Immunosuppressive Agents, Anti-Bacterial Agents, Liver Transplantation
Abstract

The authors analysed severe infections in 43 consecutive patients undergoing orthotopic liver transplant. Prophylaxis and full anti-infection monitoring was performed in all cases. Immunosuppressive therapy was administered in the form of primary cyclosporine in 27 cases and primary OKT3 in 16 cases.Twenty-seven patients are still alive (median 8 months, range 2-40) and 16 died (median 22 days, range 10-92) of whom 4 without and 12 with infection, including two deaths owing to non-correlated causes with infection after recovery. Twenty-three patients underwent 33 episodes of severe infection (plus four with inconclusive positive cultures) without any case of protozoal or viral infection. All episodes occurred within two months of surgery and affected the lung (10), abdomen (7), lung + abdomen (1), urinary tract (1), lung + urinary tract (1), as well as two diffused cases and 7 cases of isolated bacteremia deriving from the donor (1), venous catheters (3), mild otorhinolaryngeal infection (1) and two unknown sources (2). Eighteen infective agents were identified in 45 cases. The bacteria involved in single-agent episodes were: 11 Gram+, 9 Gram- and five fungi. Polymicrobic and bacterial/fungal episodes were repeatedly observed in two and two cases. Postoperative renal insufficiency significantly influenced both the incidence of and mortality due to infection. Overall mortality was also influenced by early graft function, postoperative complications and reoperations, and the incidence of infections by the portal clamping stage, reject and prolonged coma.The absence of severe viral infections and the gradual reduction of mortality caused by infection appear to be parallel to the aggressive antiviral prophylaxis, the gradual improvement of intra- and postoperative management and primary immunosuppression with OKT3.

Published
1997

35. [Abdominal tuberculous lymphadenitis simulating pancreatis cancer]

Author

V, Casolino, V, Arcuri, I, Fontana, G V, Tommasi, O, Manolitsi, R, Valente, and U, Valente

Subjects
Diagnosis, Differential, Pancreatic Neoplasms, Tuberculin Test, Abdomen, Humans, Female, Mycobacterium tuberculosis, Tuberculosis, Lymph Node, Tomography, X-Ray Computed, Aged, Ultrasonography
Abstract

The Authors report the case of a patient symptomatic for fever, weight loss and abdominal pain submitted to abdominal sonography and CT which identified a mass of the pancreatic head. The patient underwent laparotomy plus biopsy; the istologic and bacteriological diagnosis demonstrated a tuberculous lymphoadenitis in spite of a normal cutaneous tuberculin test. Abdominal localization of TBC infection therefore is increasing in epidemiological studies, and thus it must be included in the differential diagnosis of subdiaphragmatic disease.

Published
1997

36. [Renal transplantation in patients over 60 years of age. An increasing clinical reality]

Author

G V, Tommasi, V, Arcuri, M, Beatini, I, Fontana, O, Manolitsi, G L, Paraluppi, V, Casolino, and U, Valente

Subjects
Male, Age Factors, Humans, Female, Kidney Diseases, Middle Aged, Kidney Transplantation, Aged
Abstract

The elevation of the uremic population age, the longer survival of dialysis, the increasing number of elderly donors, together with the safer surgical, anesthesiological and immunological procedures have led all over the word to an improvement of over 60s patients transplantation program, with very good results. The authors present their own experience of renal transplantation in elderly recipients and a review of what is reported in the literature on the question.

Published
1997

37. [Vascular bench surgery in renal transplant]

Author

V, Casolino, G, Paraluppi, O, Manolitsi, I, Fontana, A, Antonucci, G V, Tommasi, V, Arcuri, and U, Valente

Subjects
Humans, Kidney, Kidney Transplantation, Vascular Surgical Procedures, Renal Circulation
Abstract

The development in the number of patients for renal transplants has not been matched to the kidneys supplied. On this subject the authors think that this chronic deficit could be improved by making use of all the organs by using a series of technical means during bench surgery; which enable optimisation of use of kidneys with vascular abnormalities or those injured upon removal. The authors report their experience of 450 renal transplants operated between January 1981 and December 1985 and of the evolution vascular bench surgical techniques which enable use of a considerable number of kidneys which would otherwise have been discarded. Moreover, it helped the implant, shortened surgery time without prolonging hot ischemia, and did not increase the number of complications.

Published
1997

38. A randomized study comparing cyclosporine alone vs double and triple therapy in renal transplants. The Italian Multicentre Study Group for Renal Transplantation (SIMTRe)

Author

C, Ponticelli, A, Tarantino, G P, Segoloni, V, Cambi, G, Rizzo, P, Altieri, F, Mastrangelo, M, Castagneto, M, Salvadori, U, Valente, M, Cossu, S, Federico, F, Pisani, G, Montagnino, M, Messina, L, Arisi, M, Carmellini, G, Piredda, and G, Corbetta

Subjects
Adult, Graft Rejection, Reoperation, Adolescent, Hypercholesterolemia, Middle Aged, Kidney Transplantation, Methylprednisolone, Postoperative Complications, Creatinine, Azathioprine, Cyclosporine, Humans, Drug Therapy, Combination, Steroids, Immunosuppressive Agents, Aged
Published
1997

39. [Pregnancy in women undergoing a kidney transplant. Our experience and a review of the literature]

Author

G V, Tommasi, V, Casolino, I, Fontana, M, Beatini, A, Semino, O, Manolitsi, F, Dondero, and U, Valente

Subjects
Time Factors, Pregnancy, Renal Dialysis, Humans, Female, Postoperative Period, Kidney Transplantation, Uremia
Abstract

The chances of pregnancy for uremic women are usually very low, because of hormonal balance changes which determine a strong reduction in fertility. Epidemiological studies reveal that pregnancy in hemodialyzed women in fertile patients 4.6-6 months after a well functioning kidney transplant, one fertile transplanted woman over 50 can become pregnant. In the first transplant era, pregnancy after kidney transplant was considered "a big hazard", especially because of the possible side-effects of immunosuppression drugs on foetus development, and the risk of a worsening in the mother's renal function. Therefore, women were strongly recommended to avoid pregnancy. More recently, several reported papers have shown that pregnancy can be safely carried on also by transplanted women, under careful criteria and monitoring. Our experience too, even if limited in number (4 patients) reported in this article confirms this conviction.

Published
1996

40. [Technique of vascular reconstructive bench surgery in pancreas transplantation]

Author

V, Arcuri, G V, Tommasi, I, Fontana, O, Manolitsi, S, Vassallo, V, Casolino, G L, Paraluppi, and U, Valente

Subjects
Adult, Postoperative Complications, Mesenteric Artery, Superior, Humans, Thrombosis, Pancreas Transplantation, Middle Aged, Iliac Artery, Splenic Artery, Vascular Surgical Procedures
Abstract

Vascular reconstructive bench surgery has become a basic step in pancreas transplantation, in order to prevent vascular thrombosis. The Authors describe their experience, also reporting literature results.

Published
1996

41. HLA matching in pediatric recipients of a first kidney graft. A single center analysis

Author

S, Barocci, U, Valente, R, Gusmano, F, Torre, G, Basile, I, Fontana, V, Arcuri, F, Olmi, G, Angelini, and A, Nocera

Subjects
Adolescent, HLA Antigens, Child, Preschool, Histocompatibility Testing, Graft Survival, Humans, Child, Kidney Transplantation
Abstract

We retrospectively examined the effect of HLA-A, -B, and -DR serological matching on graft survival in 88 pediatric end-stage renal disease patients who underwent primary renal transplantation. Actuarial graft survivals (GS) at 2 and 6 years in patients with zero DR mismatches (MM) (12 patients) or 1 DR MM (58 patients) were significantly higher than those in patients with 2 DR MM (18 patients) (2-year GS: 100% vs. 90% vs. 59%; 6-year GS: 100% vs. 79% vs. 59%, respectively). Because of the low number of patients in the zero DR MM group, only the GS difference between 1 DR MM and 2 DR MM had a significant result at 1 year (92% vs. 68%). No clear HLA matching effect was obtained in the HLA-A and -B loci. When DR were combined with A or B antigens (0-2 MM vs. 3-4 MM), significantly higher GS at 1, 2, and 6 years persisted for patients with 0-2 MM only in the A, DR group (96%, 94%, and 85% vs. 68%, 63%, and 56%, respectively). It is suggested that avoidance of mismatching for DR alleles at the serological level, in the selection of pediatric recipients of first cadaveric renal transplantation, leads to an improvement of both short- and longterm graft outcome.

Published
1996

44. [Interstitial radiotherapy with 125I in non-resectable pancreatic carcinoma]

Author

V, Arcuri, G V, Tommasi, V, Casolino, P, Ceppa, R, Colacino, and U, Valente

Subjects
Iodine Radioisotopes, Male, Pancreatic Neoplasms, Survival Rate, Brachytherapy, Humans, Female, Adenocarcinoma, Middle Aged, Aged, Neoplasm Staging
Abstract

The authors analyze results of 220 patients suffering from pancreatic cancer treated in their department from 1982 to 1992. Among these patients 24 of them underwent surgical operation for positioning of radioactive pills. The discussion is on indication and results of this technique, considering also what's reported in scientific literature on the argument.

Published
1995

46. Long-term follow-up of human islet autotransplantation

Author

I, Fontana, V, Arcuri, G V, Tommasi, G L, Viviani, R, Pellicci, R, Bottino, V, Casolino, R, Stubinski, and U, Valente

Subjects
Adult, Male, Time Factors, Transplantation, Heterotopic, Islets of Langerhans Transplantation, Cell Separation, Middle Aged, Transplantation, Autologous, Pancreatectomy, Liver, Pancreatitis, Chronic Disease, Humans, Female, Follow-Up Studies, Retrospective Studies
Published
1994

47. Tapered bowel segment for ureteral replacement in renal transplantation

Author

I, Fontana, V, Arcuri, E, Verrina, G, Basile, G V, Tommasi, V, Casolino, R, Stubinski, E, Podesta, R, Gusmano, and U, Valente

Subjects
Polycystic Kidney Diseases, Postoperative Complications, Ileum, Ischemia, Urinary Bladder, Methods, Humans, Kidney Failure, Chronic, Ureter, Child, Fibrosis, Kidney Transplantation
Published
1994

48. Arterial hypertension in the transplanted child: frequency and analysis of the causes

Author

I, Fontana, E, Verrina, G, Basile, V, Arcuri, R, Pellicci, G V, Tommasi, F, Perfumo, R, Gusmano, and U, Valente

Subjects
Graft Rejection, Hypertension, Renal, Adolescent, Infant, Thrombosis, Renal Artery Obstruction, Kidney Transplantation, Hypertension, Renovascular, Adrenal Cortex Hormones, Risk Factors, Child, Preschool, Hypertension, Cyclosporine, Humans, Child, Ultrasonography
Published
1994

49. [Malignant neoplasms arising 'de novo' after a kidney transplant. Our experience and a review of the literature]

Author

G V, Tommasi, V, Arcuri, I, Fontana, M, Barabino, S, Vassallo, V, Casolino, and U, Valente

Subjects
Adult, Male, Time Factors, Adolescent, Incidence, Middle Aged, Kidney Transplantation, Postoperative Complications, Italy, Child, Preschool, Neoplasms, Humans, Female, Child, Aged, Follow-Up Studies
Abstract

The incidence of "de novo" cancers in kidney transplanted patients, especially because of immunosuppressive treatment, seems to be increased. The authors analyse their experience and review the literature.

Published
1994

50. [Update on laparoscopic surgery: on the treatment of hydatid cyst of the liver and peritonitis caused by a perforated duodenal ulcer]

Author

A, Sansonetti, S, Baghini, G, Lai, V, Zeno, U, Valente, D, Nardi, M, Pochini, and C U, Casciani

Subjects
Male, Echinococcosis, Hepatic, Duodenal Ulcer, Peptic Ulcer Perforation, Humans, Laparoscopy, Middle Aged, Peritonitis
Abstract

Laparoscopic surgery represents a real innovation with respect to the traditional laparotomic way of access, owing to its undeniable advantages, both intraoperative and postoperative. This new technique reduces the complications connected with the surgical wound and with forced allerement. Therefore it allows the patient's fast recovery. Laparoscopic surgery application ground get's wider and wider every day: in fact, the authors report two medical cases, one of elective surgery (treatment of a hidatid cyst of the liver) and the other in emergency surgery (peritonitis due to perforated duodenal ulcer), both obtaining a positive result about the clinical and the postoperative timing of recovery.

Published
1993

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