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Introduction and Aim:Pregnancy is a normal physiological state during which women experience a lot of internal bodily changes. Gestational diabetes mellitus (GDM) is a complication of pregnancy which is characterized by hyperglycemia due to an error in carbohydrate metabolism. During pregnancy changes in metabolism may induce oxidant stress and it may increase in GDM. The present study was done to compare serum calcium, magnesium and total antioxidant activity in pregnant women with and without hyperglycemia. Materials and Methods: The study was conducted for a period of one year. Total 67 participants were included and their serum samples were analyzed for serum calcium magnesium and total antioxidant activity. Among these 29 were GDM (43%) and 38 were non-GDM (57%). All study subjects were on supplementation of calcium, iron and folic acid. Results: In our study, there were no significant difference in serum calcium, magnesium and antioxidant activity between GDM and non GDM women. Conclusion: Calcium, magnesium and antioxidant activitywere maintained well both in pregnant women GDM and non GDM, this may be due to beneficial effect of calcium, iron, folic acid supplementation.

Zinc oxide is a preferred choice for several optoelectronic applications owing to their unique properties, such as wider band gaps combined with high exciton binding energies. A zinc oxide thin film was grown on glass substrates through sol-gel depositing method followed by heat treatments. We prepared the zinc oxide thin films using zinc acetate dihydrate, 2-methoxy ethanol and diethanolamine as zinc alkoxide precursor, solvent and sol stabilizer respectively. Structural and optical characterizations were carried out that included X-ray diffraction, Atomic force microscopy, Profilometry and UV-Visible spectrophotometry. A coplanar configuration of device has been chosen where the structure has Zinc oxide thin film on which metal contacts of 100 nm thickness were deposited onto the films via thermal evaporation. A two probe source meter was used for I-V measurements in dark environment. I-V measurements have been done for various concentrations of biomolecules (Vitamin B6). It is found that there are variations in current for increasing concentrations.

Introduction: Inborn errors of metabolism (IEM) are a group of disorders due to deficiency of the enzyme. The symptoms are due to the accumulation of toxic substances or deficiency of products. Organic aciduria is a group of IEM which is due to errors in the metabolism of branched chain amino acids and lysine. Studies showed that methylmalonicaciduria (MMA), glutaric aciduria, branched chain aminoacidurias are more common organicaciduria. Many methods are used for detection of methylmalonic acid some of them are not affordable by developing countries. Objective: To study the role of thin layer chromatography in detection of methylmalonic aciduria in children with suspected inborn errors of metabolism. Method: Untimed urine samples were collected from 385 children with clinically suspected inborn errors of metabolism and analyzed for MMA by colour reaction and thin layer chromatography (TLC). Bromocresol green and Ortho dianisidine were the dye used for spotting MMA on TLC. Result: Among 385 children who presented with developmental delay, seizures, hypotonia were worked up for underlying inborn errors of metabolism. Of them 52 children showed positive result for MMA by thin layer chromatography. Discussion: Significant number of children showed positive result for MMA by thin layer chromatography hence the method may be useful for screening methylmalonicaciduria. Further studies required to confirm the diagnosis