1. Evaluation of Outcomes of Peritoneal Dialysis Patients in the Post-COVID-19 Period: A National Multicenter Case-Control Study from Turkey
- Author
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Savas Ozturk, Meltem Gursu, Mustafa Arici, Idris Sahin, Necmi Eren, Murvet Yilmaz, Sumeyra Koyuncu, Semahat Karahisar Sirali, Zeynep Ural, Belda Dursun, Enver Yuksel, Sami Uzun, Savaş Sipahi, Elbis Ahbap, Halil Yazici, Orcun Altunoren, Onur Tunca, Yavuz Ayar, Ebru Gok Oguz, Zulfukar Yilmaz, Serdar Kahvecioglu, Ebru Asicioglu, Aysegul Oruc, Rezzan Ataman, Zeki Aydin, Bulent Huddam, Murside Esra Dolarslan, Alper Azak, Serkan Bakırdogen, Ahmet Uğur Yalcin, Serhat Karadag, Memnune Sena Ulu, Ozkan Gungor, Elif Ari Bakir, Ali Rıza Odabas, Nurhan Seyahi, Alaattin Yildiz, Kenan Ates, GÜRSU, Meltem, Ozturk S., GÜRSU M., ARICI M., Sahin I., EREN N., Yilmaz M., Koyuncu S., Karahisar Sirali S., Ural Z., Dursun B., et al., MÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, and Huddam, Bülent
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Internal Diseases ,Fizyoloji (tıbbi) ,A NATIONAL MULTICENTER CASE-CONTROL STUDY FROM TURKEY-, NEPHROLOGY DIALYSIS TRANSPLANTATION, cilt.37, 2022 [ÖZTÜRK S., Gursu M., Arici M., Sahin I., Eren N., Yilmaz M., Ozberk S., Sirali S. K. , Ural Z., Dursun B., et al., -EVALUATION OF OUTCOMES OF PERITONEAL DIALYSIS PATIENTS IN THE POST-COVID-19 PERIOD] ,Physiology ,Urology ,Peritoneal dialysis ,Temel Tıp Bilimleri ,Life Sciences (LIFE) ,Sağlık Bilimleri ,Fundamental Medical Sciences ,Biochemistry ,BIOLOGY & BIOCHEMISTRY ,İç Hastalıkları ,Clinical Medicine (MED) ,Biyokimya ,UROLOGY & NEPHROLOGY ,Physiology (medical) ,Yaşam Bilimleri ,Health Sciences ,Biyoloji ve Biyokimya ,Klinik Tıp (MED) ,FİZYOLOJİ ,ÜROLOJİ VE NEFROLOJİ ,Outcome ,Fizyoloji ,Internal Medicine Sciences ,Klinik Tıp ,Temel Bilimler ,Life Sciences ,COVID-19 ,Dahili Tıp Bilimleri ,CLINICAL MEDICINE ,Tıp ,Nefroloji ,Human Physiology ,Nephrology ,Yaşam Bilimleri (LIFE) ,Üroloji ,Medicine ,Natural Sciences ,Complication - Abstract
Introduction: There are not enough data on the post-CO-VID-19 period for peritoneal dialysis (PD) patients affected from COVID-19. We aimed to compare the clinical and laboratory data of PD patients after COVID-19 with a control PD group. Methods: This study, supported by the Turkish Society of Nephrology, is a national, multicenter retrospective case-control study involving adult PD patients with confirmed COVID-19, using data collected from April 21, 2021, to June 11, 2021. A control PD group was also formed from each PD unit, from patients with similar characteristics but without COVID-19. Patients in the active period of COVID-19 were not included. Data at the end of the first month and within the first 90 days, as well as other outcomes, including mortality, were investigated. Results: A total of 223 patients (COVID-19 group: 113, control group: 110) from 27 centers were included. The duration of PD in both groups was similar (median [IQR]: 3.0 [1.88-6.0] years and 3.0 [2.0-5.6]), but the patient age in the COVID-19 group was lower than that in the control group (50 [IQR: 40-57] years and 56 [IQR: 46-64] years, p < 0.001). PD characteristics and baseline laboratory data were similar in both groups, except serum albumin and hemoglobin levels on day 28, which were significantly lower in the COVID-19 group. In the COVID-19 group, respiratory symptoms, rehospitalization, lower respiratory tract infection, change in PD modality, UF failure, and hypervolemia were significantly higher on the 28th day. There was no significant difference in laboratory parameters at day 90. Only 1 (0.9%) patient in the COVID-19 group died within 90 days. There was no death in the control group. Respiratory symptoms, malnutrition, and hypervolemia were significantly higher at day 90 in the COVID-19 group. Conclusion: Mortality in the first 90 days after COVID-19 in PD patients with COVID-19 was not different from the control PD group. However, some patients continued to experience significant problems, especially respiratory system symptoms, malnutrition, and hypervolemia. © 2022 S. Karger AG, Basel. Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
- Published
- 2022