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4 results on '"Tzong-Shang Yang"'

1. Subject Index Vol. 11, 2004

Author

Lee-Young Chau, Nan-Chi A. Chang, Irene Oi-Lin Ng, Li-Ling Chiu, Sheau-Fen Lee, Xiangyang Gong, Wen-Gang Chou, Marcelle Carolina Colhone, Chin-Chen Chu, Chiu-Hui Huang, Tanuja Singh, Nian-Chung Yang, Kuan-Hung Lin, Tseng-Long Yang, Yung-Hsi Kao, Alice Y.W. Chang, Qun Zhou, Pei-Ling Kang, Gong-Jhe Wu, Jerry M. Farley, Hsin-Yi Ho, Yuan Yao, Sebely Pal, Els J.M. Van Damme, Robin W. Rockhold, Eagle Yi-Kung Huang, Liang-Huei Lu, T.M. Wong, Ning-Sun Yang, Chien-Huang Lin, Yen-Bin Liu, Chia-Hua Kuo, Vijay Narayanasamy, Shao Hua Chen, Hui-Ling Chen, Jianzhong Sun, Wei-Tsung Chen, Alice Chien Chang, Yen-Mei Lee, Kuo-Long Chang, Tangen Ma, Sheue-Mei Wu, Tzu-Yang Lin, Joaquim Chan-Wang Lio, Yi-Jen Hsueh, George Hsiao, Yen-Hwa Chang, M. Chen, Kang-Chuang Chu, Chen-Yang Shen, Chau-Chung Wu, John C.L. Mamo, M.C.Y. Wong, Albert M. Wu, Steve S.-L. Chen, William Wei, Dong-Yan Jin, Desmond Hunt, C.H. Cho, Chiu-Ping Lo, Chi-Meng Tzeng, Lie-Fen Shyur, Mathew J. Palakal, Fu-Chan Wei, Andrew M. Thomson, Yah-Luen Lin, Paulus S. Wang, Fur-Jiang Leu, Wen-Kwei Chen, Shinn-Chih Wu, W.H. Kwong, Chien-Chuan Wang, Shen-Kou Tsai, David Potter, Li-Man Hung, Hong Zhu, Adriana Degrossoli, Ta-Liang Chen, Ing K. Ho, Jin Wang, Tzong-Shang Yang, Li-Shaung Ai, Yuan-Teh Lee, June H. Wu, Ming-Jai Su, Yen-Hsuan Ni, Jyh-Cherng Yu, Lai-Fa Sheu, Yi Chang, S. Wu, Wing-Keung Chu, Duen-Suey Chou, Shian-ling Ding, Chih-Huai Chen, Joen Rong Sheu, Snehasis Mukhopadhyay, Xizheng Zhang, Rodney C. Baker, Shih-Wei Chou, Samuel H.H. Chan, Xiao R. Li, Hsiao-Ping Wei, Wan-Jr Syu, Willy J. Peumans, Raymond T.F. Cheung, Wagner Welber Arrais-Silva, BeFong Chen, Chi Chang, Yi-Fan Yang, Shung-Tai Ho, Tsai-Yueh Luo, Ming-Yi Shen, Mao-Hsiung Yen, Marong Fang, Emma Allister, Jyh-Lyh Juang, Selma Giorgio, Pierre Rougé, Erik Helmerhorst, Solveig G. Ericson, Pao-Luh Tao, Chun-Hsien Yu, Mei-Hwei Chang, John L. Ivy, Abulkhair M. Mamoon, Wu Zhou, Yick-Pang Ching, Show-Jane Sun, C. Allen Chang, Yu-Min Cho, Hsiu-Chuan Liang, Sheng-Yang Wang, Fang Liao, David T. Yew, Karen Man-Fong Sze, and Lok-Hi Chow

Subjects
Index (economics), Endocrinology, Diabetes and Metabolism, Biochemistry (medical), Clinical Biochemistry, Statistics, Pharmacology (medical), Subject (documents), Cell Biology, General Medicine, Molecular Biology, Mathematics
Published
2004
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2. Contents Vol. 11, 2004

Author

Sheau-Fen Lee, Andrew M. Thomson, Yah-Luen Lin, Xizheng Zhang, Paulus S. Wang, Fur-Jiang Leu, Shao Hua Chen, Kang-Chuang Chu, C.H. Cho, Yen-Bin Liu, Chia-Hua Kuo, Chiu-Ping Lo, Gong-Jhe Wu, Eagle Yi-Kung Huang, Sebely Pal, Els J.M. Van Damme, Liang-Huei Lu, T.M. Wong, Lai-Fa Sheu, Yi Chang, Karen Man-Fong Sze, Chau-Chung Wu, Lok-Hi Chow, Hsiao-Ping Wei, Albert M. Wu, W.H. Kwong, John L. Ivy, Abulkhair M. Mamoon, Willy J. Peumans, Chiu-Hui Huang, Tanuja Singh, Nian-Chung Yang, S. Wu, Lee-Young Chau, Tsai-Yueh Luo, Robin W. Rockhold, Ta-Liang Chen, Wan-Jr Syu, Jyh-Cherng Yu, Yick-Pang Ching, Yi-Jen Hsueh, Chien-Huang Lin, Desmond Hunt, Wei-Tsung Chen, Chien-Chuan Wang, Raymond T.F. Cheung, Alice Chien Chang, Shian-ling Ding, Fang Liao, Wing-Keung Chu, William Wei, John C.L. Mamo, Wagner Welber Arrais-Silva, BeFong Chen, Jianzhong Sun, Mao-Hsiung Yen, Chin-Chen Chu, Nan-Chi A. Chang, Yen-Hwa Chang, Joen Rong Sheu, David T. Yew, Ming-Yi Shen, Wen-Gang Chou, M.C.Y. Wong, Duen-Suey Chou, Snehasis Mukhopadhyay, Ing K. Ho, Jerry M. Farley, Hsin-Yi Ho, Adriana Degrossoli, Chih-Huai Chen, Kuan-Hung Lin, Alice Y.W. Chang, Xiangyang Gong, Marong Fang, Chi Chang, Vijay Narayanasamy, Hong Zhu, Qun Zhou, Pei-Ling Kang, Shinn-Chih Wu, Yuan Yao, Irene Oi-Lin Ng, Yi-Fan Yang, Shen-Kou Tsai, Emma Allister, Shih-Wei Chou, Yung-Hsi Kao, Yuan-Teh Lee, Shung-Tai Ho, Li-Man Hung, Tzu-Yang Lin, Ming-Jai Su, Li-Ling Chiu, June H. Wu, Show-Jane Sun, Tangen Ma, C. Allen Chang, Yu-Min Cho, Fu-Chan Wei, Tseng-Long Yang, Wen-Kwei Chen, Sheng-Yang Wang, Ning-Sun Yang, George Hsiao, Yen-Mei Lee, Kuo-Long Chang, Jyh-Lyh Juang, Sheue-Mei Wu, Chun-Hsien Yu, Selma Giorgio, Chen-Yang Shen, Yen-Hsuan Ni, Chi-Meng Tzeng, Mei-Hwei Chang, Hsiu-Chuan Liang, Rodney C. Baker, Jin Wang, Samuel H.H. Chan, Pierre Rougé, Erik Helmerhorst, Solveig G. Ericson, Mathew J. Palakal, Xiao R. Li, Pao-Luh Tao, David Potter, Wu Zhou, Steve S.-L. Chen, Tzong-Shang Yang, Li-Shaung Ai, Dong-Yan Jin, Joaquim Chan-Wang Lio, Hui-Ling Chen, M. Chen, Lie-Fen Shyur, and Marcelle Carolina Colhone

Subjects
Endocrinology, Diabetes and Metabolism, Biochemistry (medical), Clinical Biochemistry, Pharmacology (medical), Cell Biology, General Medicine, Molecular Biology
Published
2004
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3. Characterization of the regulatory region of Adra2c, the gene encoding the murine alpha2C adrenoceptor subtype

Author

Wen-Kwei Chen, Shinn-Chih Wu, Tzong-Shang Yang, Kuo-Long Chang, Alice Chien Chang, Nan-Chi A. Chang, Yen-Hwa Chang, and Sheue-Mei Wu

Subjects
Central Nervous System, Transcription, Genetic, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, Amino Acid Motifs, Polymerase Chain Reaction, Mice, Start codon, Transcription (biology), Genes, Reporter, Pharmacology (medical), Tissue Distribution, Transgenes, Cloning, Molecular, Promoter Regions, Genetic, Reverse Transcriptase Polymerase Chain Reaction, Gene Transfer Techniques, Brain, Nucleic Acid Hybridization, General Medicine, Blotting, Southern, CpG site, Lac Operon, Molecular Sequence Data, Mice, Transgenic, Biology, Transfection, Islets of Langerhans, Open Reading Frames, Receptors, Adrenergic, alpha-2, Animals, Humans, Northern blot, Codon, Molecular Biology, Gene, Gene Library, Reporter gene, Base Sequence, Models, Genetic, Biochemistry (medical), Computational Biology, Promoter, Cell Biology, Blotting, Northern, beta-Galactosidase, Molecular biology, Open reading frame, CpG Islands, Transcription Factors
Abstract

The 5' flanking sequence (3,227 base pairs, bp) of the mouse Adra2c subtype gene was determined and characterized. The transcription start site was mapped to nucleotide 'A' of two initiator motifs in tandem array, i.e. 1,159 and 1,153 bp upstream from the initiation codon of the open reading frame (ORF) of Adra2c, respectively. One structural feature salient to the 5' regulatory region of Adra2c is present in the sequence 1 kb immediately upstream from the receptor ORF, which is highly enriched in GC content (76%) and CpG island counts (i.e. CpG/GpC, 146:177), and thus rich in Sp1-binding motifs. At the 3' flanking region, the polyadenylation signal was mapped to 481 bp downstream from the termination codon. The transcript defined by sequence data thereby is consistent with a size of 3 kb (brain form) determined by Northern blot analysis. The transgene, Adra2c-NN- lacZ, which links the promoter region of Adra2c to the lacZ reporter gene, was constructed in order to evaluate the functional capacity of the promoter and the putative motifs residing within the defined regulatory region (1.9 kb upstream from the ORF) in directing the reporter gene expression in vitro in transiently transfected cells and in vivo in transgenic (Tg) mice. Permissive cell types to Adra2c-NN include those derived from neural and kidney lineages. Significant Adra2c-NN-driven reporter expression in Tg mice established suggests that alpha2C adrenoceptor expression is permissive under Adra2c-NN in central (cerebral cortex, hippocampus, subthalamus, hypothalamus, superior colliculus, cerebellum, and brain stem) and peripheral (pancreatic beta-islets) tissues.

Published
2004

4. Characterization of the Regulatory Region of Adra2c, the Gene Encoding the Murine α2C Adrenoceptor Subtype.

Author

Wen-Kwei Chen, Nan-Chi A. Chang, Yen-Hwa Chang, Kuo-Long Chang, Shinn-Chih Wu, Tzong-Shang Yang, Sheue-Mei Wu, and Chien Chang, Alice

Subjects
ALPHA adrenoceptors, GENETIC transcription, TRANSGENE expression, NEURONS, LABORATORY mice
Abstract

The 5′ flanking sequence (3,227 base pairs, bp) of the mouse Adra2c subtype gene was determined and characterized. The transcription start site was mapped to nucleotide ‘A’ of two initiator motifs in tandem array, i.e. 1,159 and 1,153 bp upstream from the initiation codon of the open reading frame (ORF) of Adra2c, respectively. One structural feature salient to the 5′ regulatory region of Adra2c is present in the sequence 1 kb immediately upstream from the receptor ORF, which is highly enriched in GC content (76%) and CpG island counts (i.e. CpG/GpC, 146:177), and thus rich in Sp1-binding motifs. At the 3′ flanking region, the polyadenylation signal was mapped to 481 bp downstream from the termination codon. The transcript defined by sequence data thereby is consistent with a size of 3 kb (brain form) determined by Northern blot analysis. The transgene, Adra2c-NN- lacZ, which links the promoter region of Adra2c to the lacZ reporter gene, was constructed in order to evaluate the functional capacity of the promoter and the putative motifs residing within the defined regulatory region (1.9 kb upstream from the ORF) in directing the reporter gene expression in vitro in transiently transfected cells and in vivo in transgenic (Tg) mice. Permissive cell types to Adra2c-NN include those derived from neural and kidney lineages. Significant Adra2c-NN-driven reporter expression in Tg mice established suggests that α2C adrenoceptor expression is permissive under Adra2c-NN in central (cerebral cortex, hippocampus, subthalamus, hypothalamus, superior colliculus, cerebellum, and brain stem) and peripheral (pancreatic β-islets) tissues. Copyright © 2004 National Science Council, ROC and S. Karger AG, Basel [ABSTRACT FROM AUTHOR]

Published
2004
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