466 results on '"Turville, Stuart"'
Search Results
2. Infection and Vaccine Induced Spike Antibody Responses Against SARS-CoV-2 Variants of Concern in COVID-19-Naïve Children and Adults
- Author
-
Pillay, Aleha, Yeola, Avani, Tea, Fiona, Denkova, Martina, Houston, Samuel, Burrell, Rebecca, Merheb, Vera, Lee, Fiona X. Z., Lopez, Joseph A., Moran, Lilly, Jadhav, Ajay, Sterling, Katrina, Lai, Catherine L., Vitagliano, Tennille L., Aggarwal, Anupriya, Catchpoole, Dan, Wood, Nicholas, Phan, Tri Giang, Nanan, Ralph, Hsu, Peter, Turville, Stuart G., Britton, Philip N., and Brilot, Fabienne
- Published
- 2023
- Full Text
- View/download PDF
3. SARS-CoV-2 Omicron variant escapes neutralizing antibodies and T cell responses more efficiently than other variants in mild COVID-19 convalescents
- Author
-
Garcia-Valtanen, Pablo, Hope, Christopher M, Masavuli, Makutiro G, Yeow, Arthur Eng Lip, Balachandran, Harikrishnan, Mekonnen, Zelalem A, Al-Delfi, Zahraa, Abayasingam, Arunasingam, Agapiou, David, Stella, Alberto Ospina, Aggarwal, Anupriya, Bouras, George, Gummow, Jason, Ferguson, Catherine, O’Connor, Stephanie, McCartney, Erin M, Lynn, David J, Maddern, Guy, Gowans, Eric J, Reddi, Benjamin AJ, Shaw, David, Kok-Lim, Chuan, Beard, Michael R, Weiskopf, Daniela, Sette, Alessandro, Turville, Stuart G, Bull, Rowena A, Barry, Simon C, and Grubor-Bauk, Branka
- Subjects
Infectious Diseases ,Pneumonia & Influenza ,Pneumonia ,Prevention ,Biodefense ,Lung ,Immunization ,Vaccine Related ,Emerging Infectious Diseases ,Infection ,Good Health and Well Being ,Antibodies ,Neutralizing ,Antibodies ,Viral ,COVID-19 ,Humans ,Reinfection ,SARS-CoV-2 ,Spike Glycoprotein ,Coronavirus ,T-Lymphocytes ,T cell immunity ,Variant of Concern ,antibody response ,antigen drift ,memory B cells ,virus neutralization - Abstract
Coronavirus disease 2019 (COVID-19) convalescents living in regions with low vaccination rates rely on post-infection immunity for protection against re-infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We evaluate humoral and T cell immunity against five variants of concern (VOCs) in mild-COVID-19 convalescents at 12 months after infection with ancestral virus. In this cohort, ancestral, receptor-binding domain (RBD)-specific antibody and circulating memory B cell levels are conserved in most individuals, and yet serum neutralization against live B.1.1.529 (Omicron) is completely abrogated and significantly reduced for other VOCs. Likewise, ancestral SARS-CoV-2-specific memory T cell frequencies are maintained in >50% of convalescents, but the cytokine response in these cells to mutated spike epitopes corresponding to B.1.1.529 and B.1.351 (Beta) VOCs were impaired. These results indicate that increased antigen variability in VOCs impairs humoral and spike-specific T cell immunity post-infection, strongly suggesting that COVID-19 convalescents are vulnerable and at risk of re-infection with VOCs, thus stressing the importance of vaccination programs.
- Published
- 2022
4. Rapid spread of the SARS-CoV-2 JN.1 lineage is associated with increased neutralization evasion
- Author
-
Zhang, Lu, Dopfer-Jablonka, Alexandra, Cossmann, Anne, Stankov, Metodi V., Graichen, Luise, Moldenhauer, Anna-Sophie, Fichter, Christina, Aggarwal, Anupriya, Turville, Stuart G., Behrens, Georg M.N., Pöhlmann, Stefan, and Hoffmann, Markus
- Published
- 2024
- Full Text
- View/download PDF
5. Early trajectories of virological and immunological biomarkers and clinical outcomes in patients admitted to hospital for COVID-19: an international, prospective cohort study
- Author
-
Sahner, David, Tierney, John, Vogel, Susan E., Herpin, Betsey R., Smolskis, Mary C., McKay, Laura A., Cahill, Kelly, Crew, Page, Sardana, Ratna, Raim, Sharon Segal, Hensely, Lisa, Lorenzo, Johsua, Mock, Rebecca, Zuckerman, Judith, Atri, Negin, Miller, Mark, Vallee, David, Chung, Lucy, Kang, Nayon, Barrett, Kevin, Adam, Stacey J., Read, Sarah, Draghia-Akli, Ruxandra, Currier, Judy, Hughes, Eric, Harrigan, Rachel H., Amos, Laura, Carlsen, Amy, Carter, Anita, Collins, Gary, Davis, Bionca, Denning, Eileen, DuChene, Alain, Eckroth, Kate, Engen, Nicole, Frase, Alex, Gandits, Greg, Grund, Birgit, Harrison, Merrie, Hurlbut, Nancy, Kaiser, Payton, Koopmeiners, Joseph, Larson, Gregg, Meger, Sue, Mistry, Shweta Sharma, Murray, Thomas, Nelson, Ray, Quan, Kien, Quan, Siu Fun, Reilly, Cavan, Siegel, Lianne, Thompson, Greg, Vock, David, Walski, Jamie, Gelijns, Annetine C., Moskowitz, Alan J., Bagiella, Emilia, Moquete, Ellen, O'Sullivan, Karen, Marks, Mary E., Accardi, Evan, Kinzel, Emily, Burris, Sarah, Bedoya, Gabriela, Gupta, Lola, Overbey, Jessica R., Santos, Milerva, Gillinov, Marc A., Miller, Marissa A., Taddei-Peters, Wendy C., Fenton, Kathleen, Sandkovsky, Uriel, Gottlieb, Robert L., Mack, Michael, Berhe, Mezgebe, Haley, Clinton, Dishner, Emma, Bettacchi, Christopher, Golden, Kevin, Duhaime, Erin, Ryan, Madison, Tallmadge, Catherine, Estrada, Lorie, Jones, Felecia, Villa, Samatha, Wang, Samatha, Robert, Raven, Coleman, Tanquinisha, Clariday, Laura, Baker, Rebecca, Hurutado-Rodriguez, Mariana, Iram, Nazia, Fresnedo, Michelle, Davis, Allyson, Leonard, Kiara, Ramierez, Noelia, Thammavong, Jon, Duque, Krizia, Turner, Emma, Fisher, Tammy, Robinson, Dianna, Ransom, Desirae, Maldonado, Nicholas, Lusk, Erica, Killian, Aaron, Palacious, Adriana, Solis, Edilia, Jerrow, Janet, Watts, Matthew, Whitacre, Heather, Cothran, Elizabeth, Smith, Peter K., Barkauskas, Christina E., Vekstein, Andrew M., Ko, Emily R., Dreyer, Grace R., Stafford, Neil, Brooks, Megan, Der, Tatyana, Witte, Marie, Gamarallage, Ruwan, Franzone, John, Ivey, Noel, Lumsden, Rebecca H., Mosaly, Nilima, Mourad, Ahmaad, Holland, Thomas L., Motta, Mary, Lane, Kathleen, McGowan, Lauren M., Stout, Jennifer, Aloor, Heather, Bragg, Kennesha M., Toledo, Barvina, McLendon-Arvik, Beth, Bussadori, Barbara, Hollister, Beth A., Griffin, Michelle, Giangiacomo, Dana M., Rodriguez, Vicente, Bokhart, Gordon, Eichman, Sharon M., Parrino, Patrick E., Spindel, Stephen, Bansal, Aditya, Baumgarten, Katherine, Hand, Johnathan, Vonderhaar, Derek, Nossaman, Bobby, Sylvia Laudun, Ames, DeAnna, Broussard, Shane, Hernandez, Nilmo, Isaac, Geralyn, Dinh, Huan, Zheng, Yiling, Tran, Sonny, McDaniel, Hunter, Crovetto, Nicolle, Perin, Emerson, Costello, Briana, Manian, Prasad, Sohail, M. Rizwan, Postalian, Alexander, Hinsu, Punit, Watson, Carolyn, Chen, James, Fink, Melyssa, Sturgis, Lydia, Walker, Kim, Mahon, Kim, Parenti, Jennifer, Kappenman, Casey, Knight, Aryn, Sturek, Jeffrey M., Barros, Andrew, Enfield, Kyle B., Kadl, Alexandra, Green, China J., Simon, Rachel M., Fox, Ashley, Thornton, Kara, Adams, Amy, Badhwar, Vinay, Sharma, Sunil, Peppers, Briana, McCarthy, Paul, Krupica, Troy, Sarwari, Arif, Reece, Rebecca, Fornaresico, Lisa, Glaze, Chad, Evans, Raquel, Di, Fang, Carlson, Shawn, Aucremanne, Tanja, Tennant, Connie, Sutton, Lisa Giblin, Buterbaugh, Sabrina, Williams, Roger, Bunner, Robin, Traverse, Jay H., Rhame, Frank, Huelster, Joshua, Kethireddy, Rajesh, Davies, Irena, Salamanca, Julianne, Majeski, Christine, Skelton, Paige, Zarambo, Maria, Sarafolean, Andrea, Bowdish, Michael E., Borok, Zea, Wald-Dickler, Noah, Hutcheon, Douglass, Towfighi, Amytis, Lee, Mary, Lewis, Meghan R., Spellberg, Brad, Sher, Linda, Sharma, Aniket, Olds, Anna P., Justino, Chris, Loxano, Edward, Romero, Chris, Leong, Janet, Rodina, Valentina, Quesada, Christine, Hamilton, Luke, Escobar, Jose, Leshnower, Brad, Bender, William, Sharifpour, Milad, Miller, Jeffrey, Farrington, Woodrow, Baio, Kim T., McBride, Mary, Fielding, Michele, Mathewson, Sonya, Porte, Kristina, Maton, Missy, Ponder, Chari, Haley, Elisabeth, Spainhour, Christine, Rogers, Susan, Tyler, Derrick, Madathil, Ronson J., Rabin, Joseph, Levine, Andrea, Saharia, Kapil, Tabatabai, Ali, Lau, Christine, Gammie, James S., Peguero, Maya-Loren, McKernan, Kimberly, Audette, Mathew, Fleischmann, Emily, Akbari, Kreshta, Lee, Myounghee, Chi, Andrew, Salehi, Hanna, Pariser, Alan, Nyguyen, Phuong Tran, Moore, Jessica, Gee, Adrienne, Vincent, Shelika, Zuckerman, Richard A., Iribarne, Alexander, Metzler, Sara, Shipman, Samantha, Johnson, Haley, Newton, Crystallee, Parr, Doug, Miller, Leslie, Schelle, Beth, McLean, Sherry, Rothbaum, Howard R., Alvarez, Michael S., Kalan, Shivam P., Germann, Heather H., Hendershot, Jennifer, Moroney, Karen, Herring, Karen, Cook, Sharri, Paul, Pam, Walker-Ignasiak, Rebecca, North, Crystal, Oldmixon, Cathryn, Ringwood, Nancy, Muzikansky, Ariela, Morse, Richard, Fitzgerald, Laura, Morin, Haley D., Brower, Roy G., Reineck, Lora A., Bienstock, Karen, Steingrub, Jay H., Hou, Peter K., Steingrub, Jay S., Tidswell, Mark A., Kozikowski, Lori-Ann, Kardos, Cynthia, DeSouza, Leslie, Romain, Sarah, Thornton-Thompson, Sherell, Talmor, Daniel, Shapiro, Nathan, Andromidas, Konstantinos, Banner-Goodspeed, Valerie, Bolstad, Michael, Boyle, Katherine L., Cabrera, Payton, deVilla, Arnaldo, Ellis, Joshua C., Grafals, Ana, Hayes, Sharon, Higgins, Conor, Kurt, Lisa, Kurtzman, Nicholas, Redman, Kimberly, Rosseto, Elinita, Scaffidi, Douglas, Filbin, Michael R., Hibbert, Kathryn A., Parry, Blair, Margolin, Justin, Hillis, Brooklynn, Hamer, Rhonda, Brait, Kelsey, Beakes, Caroline, McKaig, Brenna, Kugener, Eleonore, Jones, Alan E., Galbraith, James, Nandi, Utsav, Peacock, Rebekah, Hendey, Gregory, Kangelaris, Kirsten, Ashktorab, Kimia, Gropper, Rachel, Agrawal, Anika, Yee, Kimberley J., Jauregui, Alejandra E., Zhuo, Hanjing, Almasri, Eyad, Fayed, Mohamed, Hubel, Kinsley A., Hughes, Alyssa R., Garcia, Rebekah L., Lim, George W., Chang, Steven Y., Lin, Michael Y., Vargas, Julia, Sihota, Hena, Beutler, Rebecca, Agarwal, Trisha, Wilson, Jennifer G., Vojnik, Rosemary, Perez, Cynthia, McDowell, Jordan H., Roque, Jonasel, Wang, Henry, Huebinger, Ryan M., Patel, Bela, Vidales, Elizabeth, Albertson, Timothy, Hardy, Erin, Harper, Richart, Moss, Marc A., Baduashvili, Amiran, Chauhan, Lakshmi, Douin, David J., Martinez, Flora, Finck, Lani L., Bastman, Jill, Howell, Michelle, Higgins, Carrie, McKeehan, Jeffrey, Finigan, Jay, Stubenrauch, Peter, Janssen, William J., Griesmer, Christine, VerBurg, Olivia, Hyzy, Robert C., Park, Pauline K., Nelson, Kristine, McSparron, Jake I., Co, Ivan N., Wang, Bonnie R., Jimenez, Jose, Olbrich, Norman, McDonough, Kelli, Jia, Shijing, Hanna, Sinan, Gong, Michelle N., Richardson, Lynne D., Nair, Rahul, Lopez, Brenda, Amosu, Omowunmi, Offor, Obiageli, Tzehaie, Hiwet, Nkemdirim, William, Boujid, Sabah, Mosier, Jarrod M., Hypes, Cameron, Campbell, Elizabeth Salvagio, Bixby, Billie, Gilson, Boris, Lopez, Anitza, Bime, Christian, Parthasarathy, Sairam, Cano, Ariana M., Hite, R. Duncan, Terndrup, Thomas E., Wiedemann, Herbert P., Hudock, Kristin, Tanzeem, Hammad, More, Harshada, Martinkovic, Jamie, Sellers, Susan, Houston, Judy, Burns, Mary, Kiran, Simra, Roads, Tammy, Kennedy, Sarah, Duggal, Abhijit, Thiruchelvam, Nirosshan, Ashok, Kiran, King, Alexander H., Mehkri, Omar, Dugar, Siddharth, Sahoo, Debasis, Yealy, Donald M., Angus, Derek C., Weissman, Alexandra J., Vita, Tina M., Berryman, Emily, Hough, Catherine L., Khan, Akram, Krol, Olivia F., Mills, Emmanuel, Kinjal, Mistry, Briceno, Genesis, Reddy, Raju, Hubel, Kinsley, Jouzestani, Milad K., McDougal, Madeline, Deshmukh, Rupali, Johnston, Nicholas J., Robinson, Bryce H., Gundel, Staphanie J., Katsandres, Sarah C., Chen, Peter, Torbati, Sam S., Parimon, Tanyalak, Caudill, Antonina, Mattison, Brittany, Jackman, Susan E., Chen, Po-En, Bayoumi, Emad, Ojukwu, Cristabelle, Fine, Devin, Weissberg, Gwendolyn, Isip, Katherine, Choi-Kuaea, Yunhee, Mehdikhani, Shaunt, Dar, Tahir B., Fleury Augustin, Nsole Biteghe, Tran, Dana, Dukov, Jennifer Emilow, Matusov, Yuri, Choe, June, Hindoyan, Niree A., Wynter, Timothy, Pascual, Ethan, Clapham, Gregg J., Herrera, Lisa, Caudill, Antonia, O’Mahony, D. Shane, Nyatsatsang, Sonam T., Wilson, David M., Wallick, Julie A., Duven, Alexandria M., Fletcher, Dakota D., Miller, Chadwick, Files, D. Clark, Gibbs, Kevin W., Flores, Lori S., LaRose, Mary E., Landreth, Leigha D., Palacios, D. Rafael, Parks, Lisa, Hicks, Madeline, Goodwin, Andrew J., Kilb, Edward F., Lematty, Caitlan T., Patti, Kerilyn, Grady, Abigail, Rasberry, April, Morris, Peter E., Sturgill, Jamie L., Cassity, Evan P., Dhar, Sanjay, Montgomery-Yates, Ashley A., Pasha, Sarah N., Mayer, Kirby P., Pharm.D., Brittany Bissel, Trott, Terren, Rehman, Shahnaz, de Wit, Marjolein, Mason, Jessica, Bledsoe, Joseph, Knowlton, Kirk U., Brown, Samuel, Lanspa, Michael, Leither, Lindsey, Pelton, Ithan, Armbruster, Brent P., Montgomery, Quinn, Kumar, Naresh, Fergus, Melissa, Imel, Karah, Palmer, Ghazal, Webb, Brandon, Klippel, Carolyn, Jensen, Hannah, Duckworth, Sarah, Gray, Andrew, Burke, Tyler, Knox, Dan, Lumpkin, Jenna, Aston, Valerie T., Applegate, Darrin, Serezlic, Erna, Brown, Katie, Merril, Mardee, Harris, Estelle S., Middleton, Elizabeth A., Barrios, Macy A.G., Greer, Jorden, Schmidt, Amber D., Webb, Melissa K., Paine, Roert, Callahan, Sean J., Waddoups, Lindsey J., Yamane, Misty B., Self, Wesley H., Rice, Todd W., Casey, Jonathan D., Johnson, Jakea, Gray, Christopher, Hays, Margaret, Roth, Megan, Menon, Vidya, Kasubhai, Moiz, Pillai, Anjana, Daniel, Jean, Sittler, Daniel, Kanna, Balavenkatesh, Jilani, Nargis, Amaro, Francisco, Santana, Jessica, Lyakovestsky, Aleksandr, Madhoun, Issa, Desroches, Louis Marie, Amadon, Nicole, Bahr, Alaa, Ezzat, Imaan, Guerrero, Maryanne, Padilla, Joane, Fullmer, Jessie, Singh, Inderpreet, Ali Shah, Syed Hamad, Narang, Rajeev, Mock, Polly, Shadle, Melissa, Hernandez, Brenda, Welch, Kevin, Payne, Andrea, Ertl, Gabriela, Canario, Daniel, Barrientos, Isabel, Goss, Danielle, DeVries, Mattie, Folowosele, Ibidolapo, Garner, Dorothy, Gomez, Mariana, Price, Justin, Bansal, Ekta, Wong, Jim, Faulhaber, Jason, Fazili, Tasaduq, Yeary, Brian, Ndolo, Ruth, Bryant, Christina, Smigeil, Bridgette, Robinson, Philip, Najjar, Rana, Jones, Patrice, Nguyen, Julie, Chin, Christina, Taha, Hassan, Najm, Salah, Smith, Christopher, Moore, Jason, Nassar, Talal, Gallinger, Nick, Christian, Amy, Mauer, D’Amber, Phipps, Ashley, Waters, Michael, Zepeda, Karla, Coslet, Jordan, Landazuri, Rosalynn, Pineda, Jacob, Uribe, Nicole, Garcia, Jose Ruiz, Barbabosa, Cecilia, Sandler, Kaitlyn, Overcash, J. Scott, Marquez, Adrienna, Chu, Hanh, Lee, Kia, Quillin, Kimberly, Garcia, Andrea, Lew, Pauline, Rogers, Ralph, Shehadeh, Fadi, Mylona, Evangelia K., Kaczynski, Matthew, Tran, Quynh-Lam, Benitez, Gregorio, Mishra, Biswajit, Felix, Lewis Oscar, Vafea, Maria Tsikala, Atalla, Eleftheria, Davies, Robin, Hedili, Salma, Monkeberg, Maria Andrea, Tabler, Sandra, Harrington, Britt, Meegada, Sreenath, Koripalli, Venkata Sandeep, Muddana, Prithvi, Jain, Lakshay, Undavalli, Chaitanya, Kavya, Parasa, Ibiwoye, Mofoluwaso, Akilo, Hameed, Lovette, Bryce D., Wylie, Jamie-Crystal, Smith, Diana M., Poon, Kenneth, Eckardt, Paula, Heysu, Rubio-Gomez, Sundararaman, Nithya, Alaby, Doris, Sareli, Candice, Sánchez, Adriana, Popielski, Laura, Kambo, Amy, Viens, Kimberley, Turner, Melissa, Vjecha, Michael J., Weintrob, Amy, Brar, Indira, Markowitz, Norman, Pastor, Erika, Corpuz, Roweena, Alangaden, George, McKinnon, John, Ramesh, Mayur, Herc, Erica, Yared, Nicholas, Lanfranco, Odaliz Abreu, Rivers, Emanuel, Swiderek, Jennifer, Gupta, Ariella Hodari, Pabla, Pardeep, Eliya, Sonia, Jazrawi, Jehan, Delor, Jeremy, Desai, Mona, Cook, Aaron, Jaehne, Anja Kathrina, Gill, Jasreen Kaur, Renaud, Sheri, Sarveswaran, Siva, Gardner, Edward, Scott, James, Bianchini, Monica, Melvin, Casey, Kim, Gina, Wyles, David, Kamis, Kevin, Miller, Rachel, Douglas, Ivor, Haukoos, Jason, Hicks, Carrie, Lazarte, Susana, Marines-Price, Rubria, Osuji, Alice, Agbor Agbor, Barbine Tchamba, Petersen, Tianna, Kamel, Dena, Hansen, Laura, Garcia, Angie, Cha, Christine, Mozaffari, Azadeh, Hernandez, Rosa, Cutrell, James, Kim, Mina, DellaValle, Natalie, Gonzales, Sonia, Somboonwit, Charurut, Oxner, Asa, Guerra, Lucy, Hayes, Michael, Nguyen, Thi, Tran, Thanh, Pinto, Avenette, Hatlen, Timothy, Anderson, Betty, Zepeda-Gutierrez, Ana, Martin, Dannae, Temblador, Cindi, Cuenca, Avon, Tanoviceanu, Roxanne, Prieto, Martha, Guerrero, Mario, Daar, Eric, Correa, Ramiro, Hartnell, Gabe, Wortmann, Glenn, Doshi, Saumil, Moriarty, Theresa, Gonzales, Melissa, Garman, Kristin, Baker, Jason V., Frosch, Anne, Goldsmith, Rachael, Driver, Brian, Frank, Christine, Leviton, Tzivia, Prekker, Matthew, Jibrell, Hodan, Lo, Melanie, Klaphake, Jonathan, Mackedanz, Shari, Ngo, Linh, Garcia-Myers, Kelly, Kunisaki, Ken M., Wendt, Chris, Melzer, Anne, Wetherbee, Erin, Drekonja, Dimitri, Pragman, Alexa, Hamel, Aimee, Thielen, Abbie, Hassler, Miranda, Walquist, Mary, Augenbraun, Michael, George, Jensen, Demeo, Lynette, Mishko, Motria, Thomas, Lorraine, Tatem, Luis, Dehovitz, Jack, Abassi, Mahsa, Leuck, Anne-Marie, Rao, Via, Pullen, Matthew, Luke, Darlette, LaBar, Derek, Christiansen, Theresa, Howard, Diondra, Biswas, Kousick, Harrington, Cristin, Garcia, Amanda, Bremer, Tammy, Burke, Tara, Koker, Brittany, Davis-Karim, Anne, Pittman, David, Vasudeva, Shikha S., Johnstone, Jaylynn R., Agnetti, Kate, Davis, Ruby, Trautner, Barbara, Hines-Munson, Casey, Van, John, Dillon, Laura, Wang, Yiqun, Nagy-Agren, Stephanie, Vasudeva, Shikha, Ochalek, Tracy, Caldwell, Erin, Humerickhouse, Edward, Boone, David, McGraw, William, Looney, David J., Mehta, Sanjay R., Johns, Scott Thompson, St. John, Melissa, Raceles, Jacqueline, Sear, Emily, Funk, Stephen, Cesarini, Rosa, Fang, Michelle, Nicalo, Keith, Drake, Wonder, Jones, Beatrice, Holtman, Teresa, Nguyen, Hien H., Maniar, Archana, Johnson, Eric A., Nguyen, Lam, Tran, Michelle T., Barrett, Thomas W., Johnston, Tera, Huggins, John T., Beiko, Tatsiana Y., Hughes, Heather Y., McManigle, William C., Tanner, Nichole T., Washburn, Ronald G., Ardelt, Magdalena, Tuohy, Patricia A., Mixson, Jennifer L., Hinton, Charles G., Thornley, Nicola, Allen, Heather, Elam, Shannon, Boatman, Barry, Baber, Brittany J., Ryant, Rudell, Roller, Brentin, Nguyen, Chinh, Mikail, Amani Morgan, Research, Marivic Hansen, Lichtenberger, Paola, Baracco, Gio, Ramos, Carol, Bjork, Lauren, Sueiro, Melyssa, Tien, Phyllis, Freasier, Heather, Buck, Theresa, Nekach, Hafida, Holodniy, Mark, Chary, Aarthi, Lu, Kan, Peters, Theresa, Lopez, Jessica, Tan, Susanna Yu, Lee, Robert H., Asghar, Aliya, Karyn Isip, Tasadduq Karim, Le, Katherine, Nguyen, Thao, Wong, Shinn, Raben, Dorthe, Murray, Daniel D., Jensen, Tomas O., Peters, Lars, Aagaard, Bitten, Nielsen, Charlotte B., Krapp, Katharina, Nykjær, Bente Rosdahl, Olsson, Christina, Kanne, Katja Lisa, Grevsen, Anne Louise, Joensen, Zillah Maria, Bruun, Tina, Bojesen, Ane, Woldbye, Frederik, Normand, Nick E., Esman, Frederik V.L., Benfield, Thomas, Clausen, Clara Lundetoft, Hovmand, Nichlas, Israelsen, Simone Bastrup, Iversen, Katrine, Leding, Caecilie, Pedersen, Karen Brorup, Thorlacius-Ussing, Louise, Tinggaard, Michaela, Tingsgard, Sandra, Krohn-Dehli, Louise, Pedersen, Dorthe, Villadsen, Signe, Staehr Jensen, Jens-Ulrik, Overgaard, Rikke, Rastoder, Ema, Heerfordt, Christian, Hedsund, Caroline, Ronn, Christian Phillip, Kamstrup, Peter Thobias, Hogsberg, Dorthe Sandbaek, Bergsoe, Christina, Søborg, Christian, Hissabu, Nuria M.S., Arp, Bodil C., Ostergaard, Lars, Staerke, Nina Breinholt, Yehdego, Yordanos, Sondergaard, Ane, Johansen, Isik S., Pedersen, Andreas Arnholdt, Knudtzen, Fredrikke C., Larsen, Lykke, Hertz, Mathias A., Fabricius, Thilde, Holden, Inge K., Lindvig, Susan O., Helleberg, Marie, Gerstoft, Jan, Kirk, Ole, Jensen, Tomas Ostergaard, Madsen, Birgitte Lindegaard, Pedersen, Thomas Ingemann, Harboe, Zitta Barrella, Roge, Birgit Thorup, Hansen, Thomas Michael, Glesner, Matilde Kanstrup, Lofberg, Sandra Valborg, Nielsen, Ariella Denize, Leicht von Huth, Sebastian, Nielsen, Henrik, Thisted, Rikke Krog, Petersen, Kristine Toft, Juhl, Maria Ruwald, Podlekareva, Daria, Johnsen, Stine, Andreassen, Helle Frost, Pedersen, Lars, Clara Ellinor Lindnér, Cecilia Ebba, Wiese, Lothar, Knudsen, Lene Surland, Skrøder Nytofte, Nikolaj Julian, Havmøller, Signe Ravn, Expósito, Maria, Badillo, José, Martínez, Ana, Abad, Elena, Chamorro, Ana, Figuerola, Ariadna, Mateu, Lourdes, España, Sergio, Lucero, Maria Constanza, Santos, José Ramón, Lladós, Gemma, Lopez, Cristina, Carabias, Lydia, Molina-Morant, Daniel, Loste, Cora, Bracke, Carmen, Siles, Adrian, Fernández-Cruz, Eduardo, Di Natale, Marisa, Padure, Sergiu, Gomez, Jimena, Ausin, Cristina, Cervilla, Eva, Balastegui, Héctor, Sainz, Carmen Rodríguez, Lopez, Paco, Carbone, Javier, Escobar, Mariam, Balerdi, Leire, Legarda, Almudena, Roldan, Montserrat, Letona, Laura, Muñoz, José, Camprubí, Daniel, Arribas, Jose R., Sánchez, Rocio Montejano, Díaz-Pollán, Beatriz, Stewart, Stefan Mark, Garcia, Irene, Borobia, Alberto, Mora-Rillo, Marta, Estrada, Vicente, Cabello, Noemi, Nuñez-Orantos, M.J., Sagastagoitia, I., Homen, J.R., Orviz, E., Montalvá, Adrián Sánchez, Espinosa-Pereiro, Juan, Bosch-Nicolau, Pau, Salvador, Fernando, Burgos, Joaquin, Morales-Rull, Jose Luis, Moreno Pena, Anna Maria, Acosta, Cristina, Solé-Felip, Cristina, Horcajada, Juan P., Sendra, Elena, Castañeda, Silvia, López-Montesinos, Inmaculada, Gómez-Junyent, Joan, Gonzáles, Carlota Gudiol, Cuervo, Guilermo, Pujol, Miquel, Carratalà, Jordi, Videla, Sebastià, Günthard, Huldrych, Braun, Dominique L., West, Emily, M’Rabeth-Bensalah, Khadija, Eichinger, Mareile L., Grüttner-Durmaz, Manuela, Grube, Christina, Zink, Veronika, pharmacist, Goes pharmacist, Josefine, Fätkenheuer, Gerd, Malin, Jakob J., Tsertsvadze, Tengiz, Abutidze, Akaki, Chkhartishvili, Nikoloz, Metchurtchlishvili, Revaz, Endeladze, Marina, Paciorek, Marcin, Bursa, Dominik, Krogulec, Dominika, Pulik, Piotr, Ignatowska, Anna, Horban, Andrzej, Bakowska, Elzbieta, Kowaska, Justyna, Bednarska, Agnieszka, Jurek, Natalia, Skrzat-Klapaczynska, Agata, Bienkowski, Carlo, Hackiewicz, Malgorzata, Makowiecki, Michal, Platowski, Antoni, Fishchuk, Roman, Kobrynska, Olena, Levandovska, Khrystyna, Kirieieva, Ivanna, Kuziuk, Mykhailo, Naucler, Pontus, Perlhamre, Emma, Mazouch, Lotta, Kelleher, Anthony, Polizzotto, Mark, Carey, Catherine, Chang, Christina C., Hough, Sally, Virachit, Sophie, Davidson, Sarah, Bice, Daniel J., Ognenovska, Katherine, Cabrera, Gesalit, Flynn, Ruth, Young, Barnaby E., Chia, Po Ying, Lee, Tau Hong, Lin, Ray J., Lye, David C., Ong, Sean W.X., Puah, Ser Hon, Yeo, Tsin Wen, Diong, Shiau Hui, Ongko, Juwinda, Yeo, He Ping, Eriobu, Nnakelu, Kwaghe, Vivian, Zaiyad, Habib, Idoko, Godwin, Uche, Blessing, Selvamuthu, Poongulali, Kumarasamy, Nagalingeswaran, Beulah, Faith Ester, Govindarajan, Narayan, Mariyappan, Kowsalya, Losso, Marcelo H., Abela, Cecilia, Moretto, Renzo, Belloc, Carlos G., Ludueña, Jael, Amar, Josefina, Toibaro, Javier, Macias, Laura Moreno, Fernandez, Lucia, Frare, Pablo S., Chaio, Sebastian R., Pachioli, Valeria, Timpano, Stella M., Sanchez, Marisa del Lujan, de Paz Sierra, Mariana, Stanek, Vanina, Belloso, Waldo, Cilenti, Flavia L., Valentini, Ricardo N., Stryjewski, Martin E., Locatelli, Nicolas, Soler Riera, Maria C., Salgado, Clara, Baeck, Ines M., Di Castelnuovo, Valentina, Zarza, Stella M., Hudson, Fleur, Parmar, Mahesh K.B., Goodman, Anna L., Dphil, Badrock, Jonathan, Gregory, Adam, Goodall, Katharine, Harris, Nicola, Wyncoll, James, Bhagani, S., Rodger, A., Luntiel, A., Patterson, C., Morales, J., Witele, E., Preston, A.-M., Nandani, A., Price, D.A., Hanrath, Aiden, Nell, Jeremy, Patel, Bijal, Hays, Carole, Jones, Geraldine, Davidson, Jade, Bawa, T., Mathews, M., Mazzella, A., Bisnauthsing, K., Aguilar-Jimenez, L., Borchini, F., Hammett, S., Touloumi, Giota, Pantazis, Nikos, Gioukari, Vicky, Souliou, Tania, Antoniadou, A., Protopapas, K., Kavatha, D., Grigoropoulou, S., Oikonomopoulo, C., Moschopoulos, C., Koulouris, N.G., Tzimopoulos, K., Koromilias, A., Argyraki, K., Lourida, P., Bakakos, P., Kalomenidis, I., Vlachakos, V., Barmparessou, Z., Balis, E., Zakynthinos, S., Sigala, I., Gianniou, N., Dima, E., Magkouta, S., Synolaki, E., Konstanta, S., Vlachou, M., Stathopoulou, P., Panagopoulos, P., Petrakis, V., Papazoglou, D., Tompaidou, E., Isaakidou, E., Poulakou, G., Rapti, V., Leontis, K., Nitsotolis, T., Athanasiou, K., Syrigos, K., Kyriakoulis, K., Trontzas, I., Arfara-Melanini, M., Kolonis, V., Kityo, Cissy, Mugerwa, Henry, Kiweewa, Francis, Kimuli, Ivan, Lukaakome, Joseph, Nsereko, Christoher, Lubega, Gloria, Kibirige, Moses, Nakahima, William, Wangi, Deus, Aguti, Evelyne, Generous, Lilian, Massa, Rosemary, Nalaki, Margaret, Magala, Felix, Nabaggala, Phiona Kaweesi, Kidega, Robert, Faith, Oryem Daizy, Florence, Apio, Emmanuel, Ocung, Beacham, Mugoonyi Paul, Geoffrey, Amone, Nakiboneka, Dridah, Apiyo, Paska, Kirenga, Bruce, Atukunda, Angella, Muttamba, Winters, Remmy, Kyeyume, Segawa, Ivan, Pheona, Nsubuga, Kigere, David, Mbabazi, Queen Lailah, Boersalino, Ledra, Nyakoolo, Grace, Fred, Aniongo, Alupo, Alice, Ebong, Doryn, Monday, Edson, Nalubwama, Ritah Norah, Kainja, Milton, Ambrose, Munu, Kwehayo, Vanon, Nalubega, Mary Grace, Ongoli, Augustine, Obbo, Stephen, Sebudde, Nicholus, Alaba, Jeniffer, Magombe, Geoffrey, Tino, Harriet, Obonya, Emmanuel, Lutaakome, Joseph, Kitonsa, Jonathan, Onyango, Martin, Naboth, Tukamwesiga, Naluyinda, Hadijah, Nanyunja, Regina, Irene, Muttiibwa, Jane, Biira, Wimfred, Kyobejja, Leonard, Ssemazzi, Deus, Tkiinomuhisha, Babra, Namasaba, Taire, Paul, Nabankema, Evelyn, Ogavu, Joseph, Mugerwa, Oscar, Okoth, Ivan, Mwebaze, Raymond, Mugabi, Timothy, Makhoba, Anthony, Arikiriza, Phiona, Theresa, Nabuuma, Nakayima, Hope, Frank, Kisuule, Ramgi, Patrícia, Pereira, Kássia, Osinusi, Anu, Cao, Huyen, Klekotka, Paul, Price, Karen, Nirula, Ajay, Osei, Suzette, Tipple, Craig, Wills, Angela, Peppercorn, Amanda, Watson, Helen, Gupta, Rajesh, Alexander, Elizabeth, Mogalian, Erik, Lin, Leo, Ding, Xiao, Margolis, David, Yan, Li, Girardet, Jean-Luc, Ma, Ji, Hong, Zhi, Zhu, Quing, Seegobin, Seth, Gibbs, Michael, Latchman, Mickel, Hasior, Katarzyna, Bouquet, Jerome, Wei, Jianxin, Streicher, Katie, Schmelzer, Albert, Brooks, Dennis, Butcher, Jonny, Tonev, Dimitar, Arbetter, Douglas, Damstetter, Philippe, Legenne, Philippe, Stumpp, Michael, Goncalves, Susana, Ramanathan, Krishnan, Chandra, Richa, Baseler, Beth, Teitelbaum, Marc, Schechner, Adam, Holley, H. Preston, Jankelevich, Shirley, Becker, Nancy, Dolney, Suzanne, Hissey, Debbie, Simpson, Shelly, Kim, Mi Ha, Beeler, Joy, Harmon, Liam, Asomah, Mabel, Jato, Yvonne, Stottlemyer, April, Tang, Olivia, Vanderpuye, Sharon, Yeon, Lindsey, Buehn, Molly, Eccard-Koons, Vanessa, Frary, Sadie, MacDonald, Leah, Cash, Jennifer, Hoopengardner, Lisa, Linton, Jessica, Schaffhauser, Marylu, Nelson, Michaela, Spinelli-Nadzam, Mary, Proffitt, Calvin, Lee, Christopher, Engel, Theresa, Fontaine, Laura, Osborne, C.K., Hohn, Matt, Galcik, Michael, Thompson, DeeDee, Kopka, Stacey, Shelley, Denise M., Mendez, Gregg, Brown, Shawn, Albert, Sara, Balde, Abby, Baracz, Michelle, Bielica, Mona, Billouin-Frazier, Shere, Choudary, Jay, Dixon, Mary, Eyler, Carolyn, Frye, Leanne, Gertz, Jensen, Giebeig, Lisa, Gulati, Neelam, Hankinson, Liz, Hogarty, Debi, Huber, Lynda, Krauss, Gary, Lake, Eileen, Manandhar, Meryan, Rudzinski, Erin, Sandrus, Jen, Suders, Connie, Natarajan, Ven, Rupert, Adam W., Baseler, Michael, Lynam, Danielle, Imamichi, Tom, Laverdure, Sylvain, McCormack, Ashley, Paudel, Sharada, Cook, Kyndal, Haupt, Kendra, Khan, Ayub, Hazen, Allison, Badralmaa, Yunden, Smith, Kenneth, Patel, Bhakti, Kubernac, Amanda, Kubernac, Robert, Hoover, Marie L., Solomon, Courtney, Rashid, Marium, Murphy, Joseph, Brown, Craig, DuChateau, Nadine, Ellis, Sadie, Flosi, Adam, Fox, Lisa, Johnson, Les, Nelson, Rich, Stojanovic, Jelena, Treagus, Amy, Wenner, Christine, Williams, Richard, Jensen, Tomas O, Murray, Thomas A, Grandits, Greg A, Jain, Mamta K, Shaw-Saliba, Kathryn, Matthay, Michael A, Baker, Jason V, Dewar, Robin L, Goodman, Anna L, Hatlen, Timothy J, Highbarger, Helene C, Lallemand, Perrine, Leshnower, Bradley G, Looney, David, Moschopoulos, Charalampos D, Murray, Daniel D, Mylonakis, Eleftherios, Rehman, M Tauseef, Rupert, Adam, Stevens, Randy, Turville, Stuart, Wick, Katherine, Lundgren, Jens, and Ko, Emily R
- Published
- 2024
- Full Text
- View/download PDF
6. Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients
- Author
-
Rouet, Romain, Henry, Jake Y., Johansen, Matt D., Sobti, Meghna, Balachandran, Harikrishnan, Langley, David B., Walker, Gregory J., Lenthall, Helen, Jackson, Jennifer, Ubiparipovic, Stephanie, Mazigi, Ohan, Schofield, Peter, Burnett, Deborah L., Brown, Simon H. J., Martinello, Marianne, Hudson, Bernard, Gilroy, Nicole, Post, Jeffrey J., Kelleher, Anthony, Jäck, Hans-Martin, Goodnow, Christopher C., Turville, Stuart G., Rawlinson, William D., Bull, Rowena A., Stewart, Alastair G., Hansbro, Philip M., and Christ, Daniel
- Published
- 2023
- Full Text
- View/download PDF
7. Humoral and cellular immunity to SARS-CoV-2 Ancestral and Omicron BA.5 variants following vaccination in myelofibrosis patients
- Author
-
Alcheikh, Ahmad, Perkins, Griffith B., Pucar, Phillippa A., Cecchin, Amelia, Chai, Cheng Sheng, Tunbridge, Matthew, Akerman, Anouschka, Aggarwal, Anupriya, Milogiannakis, Vanessa, Turville, Stuart, Allen, Sharon, Hissaria, Pravin, Banovic, Tatjana, Coates, P. Toby, and Ross, David M.
- Published
- 2023
- Full Text
- View/download PDF
8. The HIV-1 proviral landscape reveals Nef contributes to HIV-1 persistence in effector memory CD4+ T-cells
- Author
-
Duette, Gabriel, Hiener, Bonnie, Morgan, Hannah, Mazur, Fernando G, Mathivanan, Vennila, Horsburgh, Bethany A, Fisher, Katie, Tong, Orion, Lee, Eunok, Ahn, Haelee, Shaik, Ansari, Fromentin, Rémi, Hoh, Rebecca, Bacchus-Souffan, Charline, Nasr, Najla, Cunningham, Anthony, Hunt, Peter W, Chomont, Nicolas, Turville, Stuart G, Deeks, Steven G, Kelleher, Anthony D, Schlub, Timothy E, and Palmer, Sarah
- Subjects
HIV/AIDS ,Infectious Diseases ,Clinical Research ,Aetiology ,2.1 Biological and endogenous factors ,Infection ,CD4-Positive T-Lymphocytes ,DNA ,Viral ,HIV Infections ,HIV-1 ,Humans ,Proviruses ,Viral Load ,nef Gene Products ,Human Immunodeficiency Virus ,AIDS/HIV ,Adaptive immunity ,Infectious disease ,Molecular genetics ,T cells ,Medical and Health Sciences ,Immunology - Abstract
Despite long-term antiretroviral therapy (ART), HIV-1 persists within a reservoir of CD4+ T cells that contribute to viral rebound if treatment is interrupted. Identifying the cellular populations that contribute to the HIV-1 reservoir and understanding the mechanisms of viral persistence are necessary to achieve an effective cure. In this regard, through Full-Length Individual Proviral Sequencing, we observed that the HIV-1 proviral landscape was different and changed with time on ART across naive and memory CD4+ T cell subsets isolated from 24 participants. We found that the proportion of genetically intact HIV-1 proviruses was higher and persisted over time in effector memory CD4+ T cells when compared with naive, central, and transitional memory CD4+ T cells. Interestingly, we found that escape mutations remained stable over time within effector memory T cells during therapy. Finally, we provided evidence that Nef plays a role in the persistence of genetically intact HIV-1. These findings posit effector memory T cells as a key component of the HIV-1 reservoir and suggest Nef as an attractive therapeutic target.
- Published
- 2022
9. Immunoglobulin repertoire restriction characterizes the serological responses of patients with predominantly antibody deficiency
- Author
-
Troelnikov, Alexander, Armour, Bridie, Putty, Trishni, Aggarwal, Anupriya, Akerman, Anouschka, Milogiannakis, Vanessa, Chataway, Tim, King, Jovanka, Turville, Stuart G., Gordon, Tom P., and Wang, Jing Jing
- Published
- 2023
- Full Text
- View/download PDF
10. Novel siRNA therapeutics demonstrate multi-variant efficacy against SARS-CoV-2
- Author
-
Bowden-Reid, Ellen, Ledger, Scott, Zhang, Yuan, Di Giallonardo, Francesca, Aggarwal, Anupriya, Stella, Alberto Ospina, Akerman, Anouschka, Milogiannakis, Vanessa, Walker, Gregory, Rawlinson, William, Turville, Stuart, Kelleher, Anthony D., and Ahlenstiel, Chantelle
- Published
- 2023
- Full Text
- View/download PDF
11. Exploiting Hydrophobic Amino Acid Scanning to Develop Cyclic Peptide Inhibitors of the SARS‐CoV‐2 Main Protease with Antiviral Activity
- Author
-
Harrison, Katriona, primary, Carlos, Patrick, additional, Ullrich, Sven, additional, Aggarwal, Anupriya, additional, Johansen-Leete, Jason, additional, Mini Sasi, Vishnu, additional, Barter, Isabel, additional, Maxwell, Joshua, additional, Bedding, Max, additional, Larance, Mark, additional, Turville, Stuart, additional, Jackson, Colin, additional, Norman, Alexander, additional, Nitsche, Christoph, additional, and Payne, Richard J, additional
- Published
- 2024
- Full Text
- View/download PDF
12. Platform for isolation and characterization of SARS-CoV-2 variants enables rapid characterization of Omicron in Australia
- Author
-
Aggarwal, Anupriya, Stella, Alberto Ospina, Walker, Gregory, Akerman, Anouschka, Esneau, Camille, Milogiannakis, Vanessa, Burnett, Deborah L., McAllery, Samantha, Silva, Mariana Ruiz, Lu, Yonghui, Foster, Charles S. P., Brilot, Fabienne, Pillay, Aleha, Van Hal, Sabastiaan, Mathivanan, Vennila, Fichter, Christina, Kindinger, Andrea, Hoppe, Alexandra Carey, Munier, Mee Ling, Amatayakul-Chantler, Supavadee, Roth, Nathan, Coppola, Germano, Symonds, Geoff P., Schofield, Peter, Jackson, Jennifer, Lenthall, Helen, Henry, Jake Y., Mazigi, Ohan, Jäck, Hans-Martin, Davenport, Miles P., Darley, David R., Matthews, Gail V., Khoury, David S., Cromer, Deborah, Goodnow, Christopher C., Christ, Daniel, Robosa, Roselle, Starck, Damien J., Bartlett, Nathan W., Rawlinson, William D., Kelleher, Anthony D., and Turville, Stuart G.
- Published
- 2022
- Full Text
- View/download PDF
13. Multiple COVID-19 vaccine doses in CLL and MBL improve immune responses with progressive and high seroconversion
- Author
-
Shen, Yandong, Freeman, Jane A., Holland, Juliette, Naidu, Kartik, Solterbeck, Ann, Van Bilsen, Nenna, Downe, Paul, Kerridge, Ian, Wallman, Lucinda, Akerman, Anouschka, Aggarwal, Anupriya, Milogiannakis, Vanessa, Martins Costa Gomes, Gabriela, Doyle, Chloe M., Sandgren, Kerrie J., Turville, Stuart, Cunningham, Anthony L., and Mulligan, Stephen P.
- Published
- 2022
- Full Text
- View/download PDF
14. Mucosal TLR2-activating protein-based vaccination induces potent pulmonary immunity and protection against SARS-CoV-2 in mice
- Author
-
Ashhurst, Anneliese S., Johansen, Matt D., Maxwell, Joshua W. C., Stockdale, Skye, Ashley, Caroline L., Aggarwal, Anupriya, Siddiquee, Rezwan, Miemczyk, Stefan, Nguyen, Duc H., Mackay, Joel P., Counoupas, Claudio, Byrne, Scott N., Turville, Stuart, Steain, Megan, Triccas, James A., Hansbro, Philip M., Payne, Richard J., and Britton, Warwick J.
- Published
- 2022
- Full Text
- View/download PDF
15. Protocol for SARS-CoV-2 post-vaccine surveillance study in Australian adults and children with cancer: an observational study of safety and serological and immunological response to SARS-CoV-2 vaccination (SerOzNET)
- Author
-
Body, Amy, Ahern, Elizabeth, Lal, Luxi, Gillett, Karen, Abdulla, Hesham, Opat, Stephen, O’Brien, Tracey, Downie, Peter, Turville, Stuart, Munier, C. Mee Ling, Smith, Corey, MacIntyre, C. Raina, and Segelov, Eva
- Published
- 2022
- Full Text
- View/download PDF
16. Virtual screening and in vitro validation of natural compound inhibitors against SARS-CoV-2 spike protein
- Author
-
Power, Helen, Wu, Jiadai, Turville, Stuart, Aggarwal, Anupriya, Valtchev, Peter, Schindeler, Aaron, and Dehghani, Fariba
- Published
- 2022
- Full Text
- View/download PDF
17. Boosting immunity: synergistic antiviral effects of luteolin, vitamin C, magnesium and zinc against SARS-CoV-2 3CLpro.
- Author
-
Ferreira, Juliana C., Fadl, Samar, Cardoso, Thyago H. S., Andrade, Bruno Silva, Melo, Tarcisio S., de Andrade Silva, Edson Mario, Agarwal, Anupriya, Turville, Stuart J., Saksena, Nitin K., and Rabeh, Wael M.
- Subjects
COVID-19 ,VITAMIN C ,FLAVONOIDS ,LUTEOLIN ,COVID-19 vaccines - Abstract
SARS-CoV-2 was first discovered in 2019 and has disseminated throughout the globe to pandemic levels, imposing significant health and economic burdens. Although vaccines against SARS-CoV-2 have been developed, their long-term efficacy and specificity have not been determined, and antiviral drugs remain necessary. Flavonoids, which are commonly found in plants, fruits, and vegetables and are part of the human diet, have attracted considerable attention as potential therapeutic agents due to their antiviral and antimicrobial activities and effects on other biological activities, such as inflammation. The present study uses a combination of biochemical, cellular, molecular dynamics, and molecular docking experiments to provide compelling evidence that the flavonoid luteolin (2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one) has antiviral activity against SARS-CoV-2 3-chymotrypsin-like protease (3CLpro) that is synergistically enhanced by magnesium, zinc, and vitamin C. The IC50 of luteolin against 2 μM 3CLpro is 78 μM and decreases 10-fold to 7.6 μM in the presence of zinc, magnesium, and vitamin C. Thermodynamic stability analyses revealed that luteolin has minimal effects on the structure of 3CLpro, whereas metal ions and vitamin C significantly alter the thermodynamic stability of the protease. Interactome analysis uncovered potential host-virus interactions and functional clusters associated with luteolin activity, supporting the relevance of this flavone for combating SARS-CoV-2 infection. This comprehensive investigation sheds light on luteolin's therapeutic potential and provides insights into its mechanisms of action against SARS-CoV-2. The novel formulation of luteolin, magnesium, zinc, and vitamin C may be an effective avenue for treating COVID-19 patients. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
18. Immunisation of ferrets and mice with recombinant SARS-CoV-2 spike protein formulated with Advax-SM adjuvant protects against COVID-19 infection
- Author
-
Li, Lei, Honda-Okubo, Yoshikazu, Huang, Ying, Jang, Hyesun, Carlock, Michael A., Baldwin, Jeremy, Piplani, Sakshi, Bebin-Blackwell, Anne G., Forgacs, David, Sakamoto, Kaori, Stella, Alberto, Turville, Stuart, Chataway, Tim, Colella, Alex, Triccas, Jamie, Ross, Ted M., and Petrovsky, Nikolai
- Published
- 2021
- Full Text
- View/download PDF
19. 314.2: MTOR Inhibitors Promote Highly Functional T Cell Immunity in Kidney Transplant Recipients Vaccinated Against COVID-19
- Author
-
Perkins, Griffith, Tunbridge, Matthew, Salehi, Tania, Sheng Chai, Cheng, Hope, Christopher M, Garcia-Valtanen, Pablo, Singer, Julian J, Hurtado, Plinio R, Turville, Stuart, Hissaria, Pravin, Grubor-Bauk, Branka, Barry, Simon C, Chadban, Steven J, and Coates AO, Toby
- Published
- 2022
- Full Text
- View/download PDF
20. Virus isolation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) for diagnostic and research purposes
- Author
-
Stelzer-Braid, Sacha, Walker, Gregory J., Aggarwal, Anupriya, Isaacs, Sonia R., Yeang, Malinna, Naing, Zin, Ospina Stella, Alberto, Turville, Stuart G., and Rawlinson, William D.
- Published
- 2020
- Full Text
- View/download PDF
21. Dietary Inulin to Improve SARS-CoV-2 Vaccine Response in Kidney Transplant Recipients: The RIVASTIM-Inulin Randomised Controlled Trial.
- Author
-
Singer, Julian, Tunbridge, Matthew J., Shi, Bree, Perkins, Griffith B., Chai, Cheng Sheng, Salehi, Tania, Sim, Beatrice Z., Kireta, Svjetlana, Johnston, Julie K., Akerman, Anouschka, Milogiannakis, Vanessa, Aggarwal, Anupriya, Turville, Stuart, Hissaria, Pravin, Ying, Tracey, Wu, Huiling, Grubor-Bauk, Branka, Coates, P. Toby, and Chadban, Steven J.
- Subjects
VACCINE effectiveness ,COVID-19 vaccines ,KIDNEY transplantation ,INULIN ,SHORT-chain fatty acids - Abstract
Kidney transplant recipients are at an increased risk of hospitalisation and death from SARS-CoV-2 infection, and standard two-dose vaccination schedules are typically inadequate to generate protective immunity. Gut dysbiosis, which is common among kidney transplant recipients and known to effect systemic immunity, may be a contributing factor to a lack of vaccine immunogenicity in this at-risk cohort. The gut microbiota modulates vaccine responses, with the production of immunomodulatory short-chain fatty acids by bacteria such as Bifidobacterium associated with heightened vaccine responses in both observational and experimental studies. As SCFA-producing populations in the gut microbiota are enhanced by diets rich in non-digestible fibre, dietary supplementation with prebiotic fibre emerges as a potential adjuvant strategy to correct dysbiosis and improve vaccine-induced immunity. In a randomised, double-bind, placebo-controlled trial of 72 kidney transplant recipients, we found dietary supplementation with prebiotic inulin for 4 weeks before and after a third SARS-CoV2 mRNA vaccine to be feasible, tolerable, and safe. Inulin supplementation resulted in an increase in gut Bifidobacterium, as determined by 16S RNA sequencing, but did not increase in vitro neutralisation of live SARS-CoV-2 virus at 4 weeks following a third vaccination. Dietary fibre supplementation is a feasible strategy with the potential to enhance vaccine-induced immunity and warrants further investigation. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
22. Cross-Sectional and Longitudinal Genotype to Phenotype Surveillance of SARS-CoV-2 Variants Over the First Four Years of the COVID-19 Pandemic
- Author
-
Akerman, Anouschka, primary, Fitcher, Christina, additional, Milogiannakis, Vanessa, additional, Esneu, Camille, additional, Ruiz Silva, Mariana, additional, Ison, Timothy, additional, Lopez, Joseph A., additional, Naing, Zin, additional, Caguicla, Joanna, additional, Amatayakul-Chantler, Supavadee, additional, Roth, Nathan, additional, Manni, Sandro, additional, Hauser, Thomas, additional, Barnes, Thomas, additional, Boss, Tino, additional, Condylios, Anna, additional, Yeang, Malinna, additional, Sato, Kenta, additional, Bartlett, Nathan Wylie, additional, Darley, David R., additional, Matthews, Gail, additional, Starck, Damian, additional, Promsri, Susan, additional, Rawlinson, William, additional, Murrel, Ben, additional, Kelleher, Anthony, additional, Dwyer, Dominic, additional, Sintchenko, Vitali, additional, Kok, Jen, additional, Ellis, Sally, additional, Marris, Kelsi, additional, Knight, Elizabeth, additional, Hoad, Veronica H., additional, Irving, David, additional, Gosbell, Ian, additional, Wood, James, additional, Brilot, Fabienne, additional, Aggarwal, Anupriya, additional, and Turville, Stuart, additional
- Published
- 2024
- Full Text
- View/download PDF
23. Discovery of High Affinity Cyclic Peptide Ligands for Human ACE2 with SARS-CoV-2 Entry Inhibitory Activity
- Author
-
Bedding, Max J., primary, Franck, Charlotte, additional, Johansen-Leete, Jason, additional, Aggarwal, Anupriya, additional, Maxwell, Joshua W. C., additional, Patel, Karishma, additional, Hawkins, Paige M. E., additional, Low, Jason K. K., additional, Siddiquee, Rezwan, additional, Sani, Hakimeh Moghaddas, additional, Ford, Daniel J., additional, Turville, Stuart, additional, Mackay, Joel P., additional, Passioura, Toby, additional, Christie, Mary, additional, and Payne, Richard J., additional
- Published
- 2023
- Full Text
- View/download PDF
24. Immune profiling of COVID-19 vaccine responses in people with multiple sclerosis on B cell-depleting therapy
- Author
-
Perkins, Griffith B., primary, Hope, Christopher M., additional, Chai, Cheng Sheng, additional, Tunbridge, Matthew J., additional, Sterling, Sebastian, additional, Webb, Kevin, additional, Yap, Joey, additional, Yeow, Arthur Eng Lip, additional, Masavuli, Makutiro G., additional, Kireta, Svjetlana, additional, Zuiani, James D., additional, Akerman, Anouschka, additional, Aggarwal, Anupriya, additional, Milogiannakis, Vanessa, additional, Roberts, Matthew B., additional, Wilson, William, additional, Hurtado, Plinio R., additional, Turville, Stuart, additional, Grubor-Bauk, Branka, additional, Barry, Simon C., additional, Coates, P. Toby, additional, Ravindran, Janakan, additional, and Hissaria, Pravin, additional
- Published
- 2023
- Full Text
- View/download PDF
25. Upper Respiratory Tract OC43 Infection Model for Investigating Airway Immune-Modifying Therapies
- Author
-
Girkin, Jason L. N., primary, Bryant, Nathan E., additional, Loo, Su-Ling, additional, Hsu, Alan, additional, Kanwal, Amama, additional, Williams, Teresa C., additional, Maltby, Steven, additional, Turville, Stuart G., additional, Wark, Peter A. B., additional, and Bartlett, Nathan W., additional
- Published
- 2023
- Full Text
- View/download PDF
26. Long-term serial passaging of SARS-CoV-2 reveals signatures of convergent evolution
- Author
-
Foster, Charles S.P., primary, Walker, Gregory J, additional, Jean, Tyra, additional, Wong, Maureen, additional, Brassil, Levent, additional, Isaacs, Sonia, additional, Lu, Yonghui, additional, Turville, Stuart Grant, additional, Kelleher, Anthony, additional, and Rawlinson, William D, additional
- Published
- 2023
- Full Text
- View/download PDF
27. A single dose, BCG-adjuvanted COVID-19 vaccine provides sterilising immunity against SARS-CoV-2 infection
- Author
-
Counoupas, Claudio, Johansen, Matt D., Stella, Alberto O., Nguyen, Duc H., Ferguson, Angela L., Aggarwal, Anupriya, Bhattacharyya, Nayan D., Grey, Alice, Hutchings, Owen, Patel, Karishma, Siddiquee, Rezwan, Stewart, Erica L., Feng, Carl G., Hansbro, Nicole G., Palendira, Umaimainthan, Steain, Megan C., Saunders, Bernadette M., Low, Jason K. K., Mackay, Joel P., Kelleher, Anthony D., Britton, Warwick J., Turville, Stuart G., Hansbro, Philip M., and Triccas, James A.
- Published
- 2021
- Full Text
- View/download PDF
28. Pharmacologic hyperstabilisation of the HIV-1 capsid lattice induces capsid failure.
- Author
-
Faysal, K. M. Rifat, Walsh, James C., Renner, Nadine, Márquez, Chantal L., Shah, Vaibhav B., Tuckwell, Andrew J., Christie, Michelle P., Parker, Michael W., Turville, Stuart G., Towers, Greg J., James, Leo C., Jacques, David A., and Böcking, Till
- Published
- 2024
- Full Text
- View/download PDF
29. TMPRSS2 activation of Omicron lineage Spike glycoproteins is regulated by TMPRSS2 cleavage of ACE2
- Author
-
Aggarwal, Anupriya, primary, Fichter, Christina, additional, Milogiannakis, Vanessa, additional, Akerman, Anouschka, additional, Ison, Timothy, additional, Ruiz Silva, Mariana, additional, Esneau, Camille, additional, Bartlett, Nathan, additional, Burrell, Louise, additional, Patel, Sheila, additional, Churchill, Melissa, additional, Angelovich, Thomas, additional, Parry, Rhys, additional, Sng, Julian D, additional, Neely, Greg G, additional, Moreno, Cesar L, additional, Loo, Lipin, additional, Kelleher, Anthony D, additional, Brilot, Fabienne, additional, Khromykh, Alexander, additional, and Turville, Stuart Grant, additional
- Published
- 2023
- Full Text
- View/download PDF
30. The HIV-1 proviral landscape reveals that Nef contributes to HIV-1 persistence in effector memory [CD4.sup.+] T cells
- Author
-
Duette, Gabriel, Hiener, Bonnie, Morgan, Hannah, Mazur, Fernando G., Mathivanan, Vennila, Horsburgh, Bethany A., Fisher, Katie, Tong, Orion, Lee, Eunok, Ahn, Haelee, Shaik, Ansari, Fromentin, Remi, Hoh, Rebecca, Bacchus-Souffan, Charline, Nasr, Najla, Cunningham, Anthony L., Hunt, Peter W., Chomont, Nicolas, Turville, Stuart G., Deeks, Steven G., Kelleher, Anthony D., Schlub, Timothy E., and Palmer, Sarah
- Subjects
HIV (Viruses) -- Genetic aspects ,Immunologic memory -- Health aspects -- Genetic aspects ,T cells -- Health aspects -- Genetic aspects ,Antiviral agents -- Patient outcomes ,Viral proteins -- Health aspects -- Genetic aspects ,HIV infection -- Development and progression -- Care and treatment -- Genetic aspects ,Health care industry - Abstract
Despite long-term antiretroviral therapy (ART), HIV-1 persists within a reservoir of [CD4.sup.+] T cells that contribute to viral rebound if treatment is interrupted. Identifying the cellular populations that contribute to the HIV-1 reservoir and understanding the mechanisms of viral persistence are necessary to achieve an effective cure. In this regard, through Full-Length Individual Proviral Sequencing, we observed that the HIV-1 proviral landscape was different and changed with time on ART across naive and memory [CD4.sup.+] T cell subsets isolated from 24 participants. We found that the proportion of genetically intact HIV-1 proviruses was higher and persisted over time in effector memory [CD4.sup.+] T cells when compared with naive, central, and transitional memory [CD4.sup.+] T cells. Interestingly, we found that escape mutations remained stable over time within effector memory T cells during therapy. Finally, we provided evidence that Nef plays a role in the persistence of genetically intact HIV-1. These findings posit effector memory T cells as a key component of the HIV-1 reservoir and suggest Nef as an attractive therapeutic target., Introduction Genetic characterization of HIV-1 proviruses isolated from individuals on suppressive antiretroviral therapy (ART) has revealed that 2%-8% of persistent HIV-1 is genetically intact and potentially replication competent (1-6). Replication-competent [...]
- Published
- 2022
- Full Text
- View/download PDF
31. REGIONAL ANALYSIS OF INTACT AND DEFECTIVE HIV PROVIRUSES IN THE BRAIN OF VIREMIC AND VIRALLY SUPPRESSED PEOPLE WITH HIV
- Author
-
Angelovich, Thomas A., primary, Cochrane, Catherine R., additional, Zhou, Jingling, additional, Tumpach, Carolin, additional, Byrnes, Sarah J., additional, Jamal Eddine, Janna, additional, Waring, Emily, additional, Busman‐Sahay, Kathleen, additional, Deleage, Claire, additional, Jenkins, Trisha A., additional, Hearps, Anna C., additional, Turville, Stuart, additional, Gorry, Paul R, additional, Lewin, Sharon R., additional, Brew, Bruce J., additional, Estes, Jacob D, additional, Roche, Michael, additional, and Churchill, Melissa J., additional
- Published
- 2023
- Full Text
- View/download PDF
32. Durable reprogramming of neutralizing antibody responses following Omicron breakthrough infection
- Author
-
Lee, Wen Shi, primary, Tan, Hyon-Xhi, additional, Reynaldi, Arnold, additional, Esterbauer, Robyn, additional, Koutsakos, Marios, additional, Nguyen, Julie, additional, Amarasena, Thakshila, additional, Kent, Helen E., additional, Aggarwal, Anupriya, additional, Turville, Stuart G., additional, Taiaroa, George, additional, Kinsella, Paul, additional, Liew, Kwee Chin, additional, Tran, Thomas, additional, Williamson, Deborah A., additional, Cromer, Deborah, additional, Davenport, Miles P., additional, Kent, Stephen J., additional, Juno, Jennifer A., additional, Khoury, David S., additional, and Wheatley, Adam K., additional
- Published
- 2023
- Full Text
- View/download PDF
33. A broad-spectrum macrocyclic peptide inhibitor of the SARS-CoV-2 spike protein
- Author
-
Thijssen, Vito, primary, Hurdiss, Daniel L., additional, Debski-Antoniak, Oliver J., additional, Spence, Matthew A., additional, Franck, Charlotte, additional, Norman, Alexander, additional, Aggarwal, Anupriya, additional, Mokiem, Nadia J., additional, van Dongen, David A. A., additional, Vermeir, Stein W., additional, Liu, Minglong, additional, Li, Wentao, additional, Chatziandreou, Marianthi, additional, Donselaar, Tim, additional, Du, Wenjuan, additional, Drulyte, Ieva, additional, Bosch, Berend-Jan, additional, Snijder, Joost, additional, Turville, Stuart G., additional, Payne, Richard J., additional, Jackson, Colin J., additional, van Kuppeveld, Frank J. M., additional, and Jongkees, Seino A. K., additional
- Published
- 2023
- Full Text
- View/download PDF
34. Enhanced stability of the SARS CoV-2 spike glycoprotein following modification of an alanine cavity in the protein core
- Author
-
Poumbourios, Pantelis, primary, Langer, Christine, additional, Boo, Irene, additional, Zakir, Tasnim, additional, Center, Rob J., additional, Akerman, Anouschka, additional, Milogiannakis, Vanessa, additional, Aggarwal, Anupriya, additional, Johnstone, Bronte A., additional, Ha, Jungmin, additional, Coulibaly, Fasséli, additional, Turville, Stuart G., additional, and Drummer, Heidi E., additional
- Published
- 2023
- Full Text
- View/download PDF
35. Discovery of High Affinity Cyclic Peptide Ligands for Human ACE2 with SARS-CoV‑2 Entry Inhibitory Activity.
- Author
-
Bedding, Max J., Franck, Charlotte, Johansen-Leete, Jason, Aggarwal, Anupriya, Maxwell, Joshua W. C., Patel, Karishma, Hawkins, Paige M. E., Low, Jason K. K., Siddiquee, Rezwan, Sani, Hakimeh Moghaddas, Ford, Daniel J., Turville, Stuart, Mackay, Joel P., Passioura, Toby, Christie, Mary, and Payne, Richard J.
- Published
- 2024
- Full Text
- View/download PDF
36. Mechanisms for Controlling HIV-1 Infection: A Gene Therapy Approach
- Author
-
Ognenovska, Katherine, primary, Klemm, Vera, additional, Ledger, Scott, additional, Turville, Stuart, additional, Symonds, Geoff, additional, D. Kelleher, Anthony, additional, and L. Ahlenstiel, Chantelle, additional
- Published
- 2019
- Full Text
- View/download PDF
37. SARS-CoV-2 neutralizing antibodies: Longevity, breadth, and evasion by emerging viral variants
- Author
-
Tea, Fiona, Ospina Stella, Alberto, Aggarwal, Anupriya, Ross Darley, David, Pilli, Deepti, Vitale, Daniele, Merheb, Vera, Lee, Fiona X. Z., Cunningham, Philip, Walker, Gregory J., Fichter, Christina, Brown, David A., Rawlinson, William D., Isaacs, Sonia R., Mathivanan, Vennila, Hoffmann, Markus, Pöhlman, Stefan, Mazigi, Ohan, Christ, Daniel, Dwyer, Dominic E., Rockett, Rebecca J., Sintchenko, Vitali, Hoad, Veronica C., Irving, David O., Dore, Gregory J., Gosbell, Iain B., Kelleher, Anthony D., Matthews, Gail V., Brilot, Fabienne, and Turville, Stuart G.
- Subjects
Diseases -- Relapse ,Viral antibodies -- Health aspects ,Immune response -- Health aspects ,Antibodies -- Health aspects ,Biological sciences - Abstract
The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) antibody neutralization response and its evasion by emerging viral variants and variant of concern (VOC) are unknown, but critical to understand reinfection risk and breakthrough infection following vaccination. Antibody immunoreactivity against SARS-CoV-2 antigens and Spike variants, inhibition of Spike-driven virus-cell fusion, and infectious SARS-CoV-2 neutralization were characterized in 807 serial samples from 233 reverse transcription polymerase chain reaction (RT-PCR)-confirmed Coronavirus Disease 2019 (COVID-19) individuals with detailed demographics and followed up to 7 months. A broad and sustained polyantigenic immunoreactivity against SARS-CoV-2 Spike, Membrane, and Nucleocapsid proteins, along with high viral neutralization, was associated with COVID-19 severity. A subgroup of 'high responders' maintained high neutralizing responses over time, representing ideal convalescent plasma donors. Antibodies generated against SARS-CoV-2 during the first COVID-19 wave had reduced immunoreactivity and neutralization potency to emerging Spike variants and VOC. Accurate monitoring of SARS-CoV-2 antibody responses would be essential for selection of optimal responders and vaccine monitoring and design., Author(s): Fiona Tea 1, Alberto Ospina Stella 2, Anupriya Aggarwal 2, David Ross Darley 3,4, Deepti Pilli 1, Daniele Vitale 5, Vera Merheb 1, Fiona X. Z. Lee 1, Philip [...]
- Published
- 2021
- Full Text
- View/download PDF
38. Emergence and antibody evasion of BQ, BA.2.75 and SARS-CoV-2 recombinant sub-lineages in the face of maturing antibody breadth at the population level
- Author
-
Akerman, Anouschka, primary, Milogiannakis, Vanessa, additional, Jean, Tyra, additional, Esneau, Camille, additional, Silva, Mariana Ruiz, additional, Ison, Timothy, additional, Fichter, Christina, additional, Lopez, Joseph A., additional, Chandra, Deborah, additional, Naing, Zin, additional, Caguicla, Joanna, additional, Li, Daiyang, additional, Walker, Gregory, additional, Amatayakul-Chantler, Supavadee, additional, Roth, Nathan, additional, Manni, Sandro, additional, Hauser, Thomas, additional, Barnes, Thomas, additional, Condylios, Anna, additional, Yeang, Malinna, additional, Wong, Maureen, additional, Foster, Charles S.P., additional, Sato, Kenta, additional, Lee, Sharon, additional, Song, Yang, additional, Mao, Lijun, additional, Sigmund, Allison, additional, Phu, Amy, additional, Vande More, Ann Marie, additional, Hunt, Stephanie, additional, Douglas, Mark, additional, Caterson, Ian, additional, Britton, Warwick, additional, Sandgren, Kerrie, additional, Bull, Rowena, additional, Lloyd, Andrew, additional, Triccas, Jamie, additional, Tangye, Stuart, additional, Bartlett, Nathan W., additional, Darley, David, additional, Matthews, Gail, additional, Stark, Damien J., additional, Petoumenos, Kathy, additional, Rawlinson, William D., additional, Murrell, Ben, additional, Brilot, Fabienne, additional, Cunningham, Anthony L., additional, Kelleher, Anthony D., additional, Aggarwal, Anupriya, additional, and Turville, Stuart G., additional
- Published
- 2023
- Full Text
- View/download PDF
39. Layer-by-Layer Particles Deliver Epigenetic Silencing siRNA to HIV-1 Latent Reservoir Cell Types
- Author
-
Czuba-Wojnilowicz, Ewa, primary, Klemm, Vera, additional, Cortez-Jugo, Christina, additional, Turville, Stuart, additional, Aggarwal, Anupriya, additional, Caruso, Frank, additional, Kelleher, Anthony D., additional, and Ahlenstiel, Chantelle L., additional
- Published
- 2023
- Full Text
- View/download PDF
40. Durable reprogramming of neutralising antibody responses following breakthrough Omicron infection
- Author
-
Lee, Wen Shi, primary, Tan, Hyon-Xhi, additional, Reynaldi, Arnold, additional, Esterbauer, Robyn, additional, Koutsakos, Marios, additional, Nguyen, Julie, additional, Amarasena, Thakshila, additional, Kent, Helen E, additional, Aggarwal, Anupriya, additional, Turville, Stuart G, additional, Taiaroa, George, additional, Kinsella, Paul, additional, Liew, Kwee Chin, additional, Tran, Thomas, additional, Williamson, Deborah A, additional, Cromer, Deborah, additional, Davenport, Miles P, additional, Kent, Stephen J, additional, Juno, Jennifer A, additional, Khoury, David S, additional, and Wheatley, Adam K, additional
- Published
- 2023
- Full Text
- View/download PDF
41. P-Selectin promotes SARS-CoV-2 interactions with platelets and the endothelium
- Author
-
Moreno, Cesar L., primary, Castanheira, Fernanda V. S., additional, Stella, Alberto Ospina, additional, Chung, Felicity, additional, Aggarwal, Anupriya, additional, Cole, Alexander J., additional, Loo, Lipin, additional, Dupuy, Alexander, additional, Kong, Yvonne, additional, Hagimola, Lejla, additional, Fenwick, Jemma, additional, Coleman, Paul, additional, Willson, Michelle, additional, Bui-Marinos, Maxwell, additional, Hesselson, Daniel, additional, Gamble, Jennifer, additional, Passam, Freda, additional, Turville, Stuart, additional, Kubes, Paul, additional, and Neely, G. Gregory, additional
- Published
- 2023
- Full Text
- View/download PDF
42. Fibroblast-expressed LRRC15 is a receptor for SARS-CoV-2 spike and controls antiviral and antifibrotic transcriptional programs
- Author
-
Loo, Lipin, primary, Waller, Matthew A., additional, Moreno, Cesar L., additional, Cole, Alexander J., additional, Stella, Alberto Ospina, additional, Pop, Oltin-Tiberiu, additional, Jochum, Ann-Kristin, additional, Ali, Omar Hasan, additional, Denes, Christopher E., additional, Hamoudi, Zina, additional, Chung, Felicity, additional, Aggarwal, Anupriya, additional, Low, Jason K. K., additional, Patel, Karishma, additional, Siddiquee, Rezwan, additional, Kang, Taeyoung, additional, Mathivanan, Suresh, additional, Mackay, Joel P., additional, Jochum, Wolfram, additional, Flatz, Lukas, additional, Hesselson, Daniel, additional, Turville, Stuart, additional, and Neely, G. Gregory, additional
- Published
- 2023
- Full Text
- View/download PDF
43. Imprinted repertoire restriction in immunodeficiency
- Author
-
Troelnikov, Alexander, primary, Armour, Bridie, additional, Putty, Trishni, additional, Aggarwal, Anupriya, additional, Akerman, Anouschka, additional, Milogiannakis, Vanessa, additional, Chataway, Tim, additional, King, Jovanka, additional, Turville, Stuart, additional, Gordon, Tom P., additional, and Wang, Jing Jing, additional
- Published
- 2023
- Full Text
- View/download PDF
44. A broad-spectrum macrocyclic peptide inhibitor of the SARS-CoV-2 spike protein
- Author
-
Afd Chemical Biology and Drug Discovery, Virologie, Sub Biomol.Mass Spectrometry & Proteom., Infectious Diseases and Immunology - Virology, Thijssen, Vito, Hurdiss, Daniel L, Debski-Antoniak, Oliver J, Spence, Matthew A, Franck, Charlotte, Norman, Alexander, Aggarwal, Anupriya, Mokiem, Nadia J, van Dongen, David A A, Vermeir, Stein W, Liu, Minglong, Li, Wentao, Chatziandreou, Marianthi, Donselaar, Tim, Du, Wenjuan, Drulyte, Ieva, Bosch, Berend-Jan, Snijder, Joost, Turville, Stuart G, Payne, Richard J, Jackson, Colin J, van Kuppeveld, Frank J M, Jongkees, Seino A K, Afd Chemical Biology and Drug Discovery, Virologie, Sub Biomol.Mass Spectrometry & Proteom., Infectious Diseases and Immunology - Virology, Thijssen, Vito, Hurdiss, Daniel L, Debski-Antoniak, Oliver J, Spence, Matthew A, Franck, Charlotte, Norman, Alexander, Aggarwal, Anupriya, Mokiem, Nadia J, van Dongen, David A A, Vermeir, Stein W, Liu, Minglong, Li, Wentao, Chatziandreou, Marianthi, Donselaar, Tim, Du, Wenjuan, Drulyte, Ieva, Bosch, Berend-Jan, Snijder, Joost, Turville, Stuart G, Payne, Richard J, Jackson, Colin J, van Kuppeveld, Frank J M, and Jongkees, Seino A K
- Published
- 2023
45. Delivery of gene therapy to resting immune cells for an HIV cure
- Author
-
Ahlenstiel, Chantelle L. and Turville, Stuart G.
- Published
- 2019
- Full Text
- View/download PDF
46. Immune response to COVID‐19 vaccination in patients with Waldenström macroglobulinaemia who pause their BTKi therapy.
- Author
-
Rankin, Katherine, Hastak, Priyanka, Wong, Alexander, Sasson, Sarah C., Beaton, Brendan, Yeola, Avani, Warden, Andrew, Turville, Stuart, Kelleher, Anthony D., Brilot, Fabienne, and Trotman, Judith
- Published
- 2023
- Full Text
- View/download PDF
47. Emergence and antibody evasion of BQ, BA.2.75 and SARS-CoV-2 recombinant sublineages in the face of maturing antibody breadth at the population level
- Author
-
Akerman, Anouschka, primary, Milogiannakis, Vanessa, additional, Jean, Tyra, additional, Esneau, Camille, additional, Silva, Mariana Ruiz, additional, Ison, Timothy, additional, Fitcher, Christina, additional, Lopez, Joseph A, additional, Chandra, Deborah, additional, Naing, Zin, additional, Caguicla, Joanna, additional, Li, Daiyang, additional, Walker, Gregory, additional, Amatayakul-Chantler, Supavadee, additional, Roth, Nathan, additional, Manni, Sandro, additional, Hauser, Thomas, additional, Barnes, Thomas, additional, Condylios, Anna, additional, Yeang, Malinna, additional, Wong, Maureen, additional, Foster, Charles S.P., additional, Sato, Kenta, additional, Lee, Sharon, additional, Song, Yang, additional, Mao, Lijun, additional, Sigmund, Allison, additional, Phu, Amy, additional, Vande More, Ann Marie, additional, Hunt, Stephanie, additional, Douglas, Mark, additional, Caterson, Ian, additional, Sandgren, Kerrie, additional, Bull, Rowena, additional, Lloyd, Andrew, additional, Triccas, Jamie, additional, Tangye, Stuart, additional, Bartlett, Nathan W, additional, Darley, David, additional, Matthews, Gail, additional, Stark, Damien J., additional, Rawlinson, William D., additional, Murrell, Ben, additional, Brilot, Fabienne, additional, Cunningham, Anthony L, additional, Kelleher, Anthony D., additional, Aggarwal, Anupriya, additional, and Turville, Stuart G., additional
- Published
- 2022
- Full Text
- View/download PDF
48. Infection and vaccine induced Spike antibody responses against SARS-CoV-2 Variants of concern in immune naïve children and adults
- Author
-
Pillay, Aleha, primary, Yeola, Avani, additional, Tea, Fiona, additional, Denkova, Martina, additional, Houston, Samuel, additional, Burrell, Rebecca, additional, Merheb, Vera, additional, Lee, Fiona X. Z., additional, Moran, Lilly, additional, Jadhav, Ajay, additional, Sterling, Katrina, additional, Lai, Catherine L, additional, Vitagliano, Tennille L., additional, Aggarwal, Anupriya, additional, Catchpoole, Daniel, additional, Wood, Nicholas, additional, Phan, Tri Giang, additional, Nanan, Ralph, additional, Hsu, Peter, additional, Turville, Stuart G, additional, Britton, Philip N, additional, and Brilot, Fabienne, additional
- Published
- 2022
- Full Text
- View/download PDF
49. High titre neutralizing antibodies in response to SARS–CoV–2 infection require RBD–specific CD4 T cells that include proliferative memory cells
- Author
-
Phetsouphanh, Chansavath, primary, Khoo, Weng Hua, additional, Jackson, Katherine, additional, Klemm, Vera, additional, Howe, Annett, additional, Aggarwal, Anupriya, additional, Akerman, Anouschka, additional, Milogiannakis, Vanessa, additional, Stella, Alberto Ospina, additional, Rouet, Romain, additional, Schofield, Peter, additional, Faulks, Megan L., additional, Law, Hannah, additional, Danwilai, Thidarat, additional, Starr, Mitchell, additional, Munier, C. Mee Ling, additional, Christ, Daniel, additional, Singh, Mandeep, additional, Croucher, Peter I., additional, Brilot-Turville, Fabienne, additional, Turville, Stuart, additional, Phan, Tri Giang, additional, Dore, Gregory J., additional, Darley, David, additional, Cunningham, Philip, additional, Matthews, Gail V., additional, Kelleher, Anthony D., additional, and Zaunders, John J., additional
- Published
- 2022
- Full Text
- View/download PDF
50. Author response: Pharmacologic hyperstabilisation of the HIV-1 capsid lattice induces capsid failure
- Author
-
Faysal, KM Rifat, primary, Walsh, James C, primary, Renner, Nadine, primary, Márquez, Chantal L, primary, Shah, Vaibhav B, additional, Tuckwell, Andrew J, additional, Christie, Michelle P, additional, Parker, Michael W, additional, Turville, Stuart G, additional, Towers, Greg J, additional, James, Leo C, additional, Jacques, David A, additional, and Böcking, Till, additional
- Published
- 2022
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.