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4. Long term follow-up of “full metal jacket” of de novo coronary lesions with new generation Zotarolimus-eluting stents

Author

Durante, Alessandro, Foglia Manzillo, Giovanni, Burzotta, Francesco, Trani, Carlo, Aurigemma, Cristina, Summaria, Francesco, Patrizi, Roberto, Talarico, Giovanni Paolo, Latib, Azeem, Figini, Filippo, Romagnoli, Enrico, De Vita, Mariarosaria, Fantoni, Cecilia, My, Luigi, Larosa, Claudio, Manzoli, Alessandro, Turturo, Maurizio, Berni, Andrea, and Corrado, Giovanni

Published
2016
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7. Acute Kidney Injury After Radial or Femoral Access for Invasive Acute Coronary Syndrome Management: AKI-MATRIX

Author

Andã², Giuseppe, Cortese, Bernardo, Russo, Filippo, Rothenbã¼hler, Martina, Frigoli, Enrico, Briguori, Carlo, Vranckx, Pascal, Leonardi, Sergio, Guiducci, Vincenzo, Belloni, Flavia, Ferrari, Fabio, De La Torre Hernandez, Jose Maria, Curello, Salvatore, Liistro, Francesco, Perkan, Andrea, De Servi, Stefano, Casu, Gavino, Dellavalle, Antonio, Fischetti, Dionigi, Micari, Antonio, Loi, Bruno, Mangiacapra, Fabio, Russo, Nunzio, Tarantino, Fabio, Saia, Francesco, Heg, Dik, Windecker, Stephan, Jã¼ni, Peter, Valgimigli, Marco, Salomone, Maria, Occhilupo, Pierpaolo, Lodolini, Veronica, Monti, Monia, Mazzone, Maria Grazia, Delos, Erika, Caruso, Maria Teresa, Testa, Maggie, Ciociano, Nestor, Lazzero, Maurizio, Gazzotti, Davide, Cagliari, Lorenzo, Shahmohammadi, Leila, Caiazza, Martina, Virga, Vittorio, Guerra, Elena, Michalska, Eva, Castellini, Sara, Serino, Vincenzo, Visconti, Gabriella, Pendenza, Gianluca, Portolan, Monica, Anzini, Marco, Silvetti, Elisa, Coco, Tiziana, Costa, Francesco, Ariotti, Sara, Valli, Linda, Adamo, Marianna, Marino, Marcello, Tricoci, Pierluigi, Gagnor, Andrea, Calabrã, Paolo, Rubartelli, Paolo, Garducci, Stefano, Santarelli, Andrea, Galli, Mario, Garbo, Roberto, Bramucci, Ezio, Ierna, Salvatore, Limbruno, Ugo, Violini, Roberto, Presbitero, Patrizia, De Cesare, Nicoletta, Sganzerla, Paolo, Ausiello, Arturo, Tosi, Paolo, Sardella, Gennaro, Sabate, Manel, Brugaletta, Salvatore, Saccone, Giovanni, Vandoni, Pietro, Zingarelli, Antonio, Liso, Armando, Rigattieri, Stefano, Di Lorenzo, Emilio, Vigna, Carlo, Palmieri, Cataldo, Falcone, Camillo, De Caterina, Raffaele, Caputo, Marcello, Lupi, Alessandro, Mazzarotto, Pietro, Varbella, Fernando, Zaro, Tiziana, Nazzaro, Marco, Rao, Sunil V., Van‘t Hof, Arnoud W. J., Omerovic, Elmir, Calabrã², Paolo, Campo, Gianluca, Uguccioni, Lucia, Tamburino, Corrado, Zavalloni parenti, Dennis, Ceravolo, Roberto, Pasquetto, Giampaolo, Esposito, Giovanni, Mameli, Stefano, Stochino, Maria Letizia, Cremonesi, Alberto, Abate, Fabio, Picchi, Andrea, Colangelo, Salvatore, Boccuzzi, Giacomo, Varbella, Ferdinando, Tresoldi, Stefano, Contarini, Marco, Evola, Rosario, Creaco, Manuela, Colombo, Antonio, Chieffo, Alaide, Sciahbasi, Alessandro, Pucci, Edoardo, Romagnoli, Enrico, Moretti, Claudio, Moretti, Luciano, Zimmarino, Marco, Ferrario, Maurizio, Turturo, Maurizio, Bonmassari, Roberto, Penzo, Carlo, Mauro, Ciro, Petronio, Anna Sonia, Gabrielli, Gabriele, Amico, Francesco, Comeglio, Marco, Fresco, Claudio, Van Mieghem, Nicolas, Diletti, Roberto, Regar, Evelyn, Sabatã©, Manel, Gã³mez Hospital, Joan Antoni, Dã­az Fernã¡ndez, Josã© Francisco, Mainar, Vicente, GARGIULO, GIUSEPPE, ESPOSITO, GIOVANNI, Andã², Giuseppe, Cortese, Bernardo, Russo, Filippo, Rothenbã¼hler, Martina, Frigoli, Enrico, Gargiulo, Giuseppe, Briguori, Carlo, Vranckx, Pascal, Leonardi, Sergio, Guiducci, Vincenzo, Belloni, Flavia, Ferrari, Fabio, De La Torre Hernandez, Jose Maria, Curello, Salvatore, Liistro, Francesco, Perkan, Andrea, De Servi, Stefano, Casu, Gavino, Dellavalle, Antonio, Fischetti, Dionigi, Micari, Antonio, Loi, Bruno, Mangiacapra, Fabio, Russo, Nunzio, Tarantino, Fabio, Saia, Francesco, Heg, Dik, Windecker, Stephan, Jã¼ni, Peter, Valgimigli, Marco, Salomone, Maria, Occhilupo, Pierpaolo, Lodolini, Veronica, Monti, Monia, Mazzone, Maria Grazia, Delos, Erika, Caruso, Maria Teresa, Testa, Maggie, Ciociano, Nestor, Lazzero, Maurizio, Gazzotti, Davide, Cagliari, Lorenzo, Shahmohammadi, Leila, Caiazza, Martina, Virga, Vittorio, Guerra, Elena, Michalska, Eva, Castellini, Sara, Serino, Vincenzo, Visconti, Gabriella, Pendenza, Gianluca, Portolan, Monica, Anzini, Marco, Silvetti, Elisa, Coco, Tiziana, Costa, Francesco, Ariotti, Sara, Valli, Linda, Adamo, Marianna, Marino, Marcello, Tricoci, Pierluigi, Gagnor, Andrea, Calabrã, Paolo, Rubartelli, Paolo, Garducci, Stefano, Santarelli, Andrea, Galli, Mario, Garbo, Roberto, Bramucci, Ezio, Ierna, Salvatore, Limbruno, Ugo, Violini, Roberto, Presbitero, Patrizia, De Cesare, Nicoletta, Sganzerla, Paolo, Ausiello, Arturo, Tosi, Paolo, Sardella, Gennaro, Sabate, Manel, Brugaletta, Salvatore, Saccone, Giovanni, Vandoni, Pietro, Zingarelli, Antonio, Liso, Armando, Rigattieri, Stefano, Di Lorenzo, Emilio, Vigna, Carlo, Palmieri, Cataldo, Falcone, Camillo, De Caterina, Raffaele, Caputo, Marcello, Esposito, Giovanni, Lupi, Alessandro, Mazzarotto, Pietro, Varbella, Fernando, Zaro, Tiziana, Nazzaro, Marco, Rao, Sunil V., Vanâ t Hof, Arnoud W. J., Omerovic, Elmir, Calabrã², Paolo, Campo, Gianluca, Uguccioni, Lucia, Tamburino, Corrado, Zavalloni parenti, Denni, Ceravolo, Roberto, Pasquetto, Giampaolo, Mameli, Stefano, Stochino, Maria Letizia, Cremonesi, Alberto, Abate, Fabio, Picchi, Andrea, Colangelo, Salvatore, Boccuzzi, Giacomo, Varbella, Ferdinando, Tresoldi, Stefano, Contarini, Marco, Evola, Rosario, Creaco, Manuela, Colombo, Antonio, Chieffo, Alaide, Sciahbasi, Alessandro, Pucci, Edoardo, Romagnoli, Enrico, Moretti, Claudio, Moretti, Luciano, Zimmarino, Marco, Ferrario, Maurizio, Turturo, Maurizio, Bonmassari, Roberto, Penzo, Carlo, Mauro, Ciro, Petronio, Anna Sonia, Gabrielli, Gabriele, Amico, Francesco, Comeglio, Marco, Fresco, Claudio, Van Mieghem, Nicola, Diletti, Roberto, Regar, Evelyn, Sabatã©, Manel, Gã³mez Hospital, Joan Antoni, Dã­az Fernã¡ndez, Josã© Francisco, and Mainar, Vicente

Subjects
estimated glomerular filtration rate, creatinine, coronary intervention, ST-segment elevation, bleeding, Cardiology and Cardiovascular Medicine
Published
2017

8. Radial versus femoral access and bivalirudin versus unfractionated heparin in invasively managed patients with acute coronary syndrome (MATRIX): final 1-year results of a multicentre, randomised controlled trial

Author

Valgimigli, Marco, primary, Frigoli, Enrico, additional, Leonardi, Sergio, additional, Vranckx, Pascal, additional, Rothenbühler, Martina, additional, Tebaldi, Matteo, additional, Varbella, Ferdinando, additional, Calabrò, Paolo, additional, Garducci, Stefano, additional, Rubartelli, Paolo, additional, Briguori, Carlo, additional, Andó, Giuseppe, additional, Ferrario, Maurizio, additional, Limbruno, Ugo, additional, Garbo, Roberto, additional, Sganzerla, Paolo, additional, Russo, Filippo, additional, Nazzaro, Marco, additional, Lupi, Alessandro, additional, Cortese, Bernardo, additional, Ausiello, Arturo, additional, Ierna, Salvatore, additional, Esposito, Giovanni, additional, Ferrante, Giuseppe, additional, Santarelli, Andrea, additional, Sardella, Gennaro, additional, de Cesare, Nicoletta, additional, Tosi, Paolo, additional, van 't Hof, Arnoud, additional, Omerovic, Elmir, additional, Brugaletta, Salvatore, additional, Windecker, Stephan, additional, Heg, Dik, additional, Jüni, Peter, additional, Campo, Gianluca, additional, Uguccioni, Lucia, additional, Tamburino, Corrado, additional, Presbitero, Patrizia, additional, Zavalloni-Parenti, Dennis, additional, Ferrari, Fabio, additional, Ceravolo, Roberto, additional, Tarantino, Fabio, additional, Pasquetto, Giampaolo, additional, Casu, Gavino, additional, Mameli, Stefano, additional, Stochino, Maria Letizia, additional, Mazzarotto, Pietro, additional, Cremonesi, Alberto, additional, Saia, Francesco, additional, Saccone, Giovanni, additional, Abate, Fabio, additional, Picchi, Andrea, additional, Violini, Roberto, additional, Colangelo, Salvatore, additional, Boccuzzi, Giacomo, additional, Guiducci, Vincenzo, additional, Vigna, Carlo, additional, Zingarelli, Antonio, additional, Gagnor, Andrea, additional, Zaro, Tiziana, additional, Tresoldi, Simone, additional, Vandoni, Pietro, additional, Contarini, Marco, additional, Liso, Armando, additional, Dellavalle, Antonio, additional, Curello, Salvatore, additional, Mangiacapra, Fabio, additional, Evola, Rosario, additional, Palmieri, Cataldo, additional, Falcone, Camillo, additional, Liistro, Francesco, additional, Creaco, Manuela, additional, Colombo, Antonio, additional, Chieffo, Alaide, additional, Perkan, Andrea, additional, De Servi, Stefano, additional, Fischetti, Dionigi, additional, Rigattieri, Stefano, additional, Sciahbasi, Alessandro, additional, Pucci, Edoardo, additional, Romagnoli, Enrico, additional, Moretti, Claudio, additional, Moretti, Luciano, additional, De Caterina, Raffaele, additional, Caputo, Marcello, additional, Zimmarino, Marco, additional, Bramucci, Ezio, additional, Di Lorenzo, Emilio, additional, Turturo, Maurizio, additional, Bonmassari, Roberto, additional, Penzo, Carlo, additional, Loi, Bruno, additional, Mauro, Ciro, additional, Petronio, Anna Sonia, additional, Gabrielli, Gabriele, additional, Micari, Antonio, additional, Belloni, Flavia, additional, Amico, Francesco, additional, Comeglio, Marco, additional, Fresco, Claudio, additional, Klinieken, Isala, additional, Van Mieghem, Nicolas, additional, Diletti, Roberto, additional, Regar, Evelyn, additional, Sabaté, Manel, additional, Gómez Hospital, Joan Antoni, additional, Díaz Fernández, José Francisco, additional, Mainar, Vicente, additional, and de la Torre Hernandez, Jose Maria, additional

Published
2018
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9. TCT-509 Eighteen-month results of high-risk patients treated with ultrathin-strut biodegradable-polymer Orsiro DES. The Bioflow-III Satellite Italy Subgroups analysis.

Author

Galli, Stefano, primary, Versaci, Francesco, additional, Briguori, Carlo, additional, Tomai, Fabrizio, additional, Poli, Arnaldo, additional, Vigna, Carlo, additional, My, Luigi, additional, Masi, Filippo, additional, Turturo, Maurizio, additional, and Bartorelli, Antonio, additional

Published
2018
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10. Acute Kidney Injury After Radial or Femoral Access for Invasive Acute Coronary Syndrome Management

Author

Andò, Giuseppe, primary, Cortese, Bernardo, additional, Russo, Filippo, additional, Rothenbühler, Martina, additional, Frigoli, Enrico, additional, Gargiulo, Giuseppe, additional, Briguori, Carlo, additional, Vranckx, Pascal, additional, Leonardi, Sergio, additional, Guiducci, Vincenzo, additional, Belloni, Flavia, additional, Ferrari, Fabio, additional, de la Torre Hernandez, Jose Maria, additional, Curello, Salvatore, additional, Liistro, Francesco, additional, Perkan, Andrea, additional, De Servi, Stefano, additional, Casu, Gavino, additional, Dellavalle, Antonio, additional, Fischetti, Dionigi, additional, Micari, Antonio, additional, Loi, Bruno, additional, Mangiacapra, Fabio, additional, Russo, Nunzio, additional, Tarantino, Fabio, additional, Saia, Francesco, additional, Heg, Dik, additional, Windecker, Stephan, additional, Jüni, Peter, additional, Valgimigli, Marco, additional, Salomone, Maria, additional, Occhilupo, Pierpaolo, additional, Lodolini, Veronica, additional, Monti, Monia, additional, Mazzone, Maria Grazia, additional, Delos, Erika, additional, Caruso, Maria Teresa, additional, Testa, Maggie, additional, Ciociano, Nestor, additional, Lazzero, Maurizio, additional, Gazzotti, Davide, additional, Cagliari, Lorenzo, additional, Shahmohammadi, Leila, additional, Caiazza, Martina, additional, Virga, Vittorio, additional, Guerra, Elena, additional, Michalska, Eva, additional, Castellini, Sara, additional, Serino, Vincenzo, additional, Visconti, Gabriella, additional, Pendenza, Gianluca, additional, Portolan, Monica, additional, Anzini, Marco, additional, Silvetti, Elisa, additional, Coco, Tiziana, additional, Costa, Francesco, additional, Ariotti, Sara, additional, Valli, Linda, additional, Adamo, Marianna, additional, Marino, Marcello, additional, Tricoci, Pierluigi, additional, Gagnor, Andrea, additional, Calabrò, Paolo, additional, Rubartelli, Paolo, additional, Garducci, Stefano, additional, Andò, Giuseppe, additional, Santarelli, Andrea, additional, Galli, Mario, additional, Garbo, Roberto, additional, Bramucci, Ezio, additional, Ierna, Salvatore, additional, Limbruno, Ugo, additional, Violini, Roberto, additional, Presbitero, Patrizia, additional, de Cesare, Nicoletta, additional, Sganzerla, Paolo, additional, Ausiello, Arturo, additional, Tosi, Paolo, additional, Sardella, Gennaro, additional, Sabate’, Manel, additional, Brugaletta, Salvatore, additional, Saccone, Giovanni, additional, Vandoni, Pietro, additional, Zingarelli, Antonio, additional, Liso, Armando, additional, Rigattieri, Stefano, additional, Di Lorenzo, Emilio, additional, Vigna, Carlo, additional, Palmieri, Cataldo, additional, Falcone, Camillo, additional, De Caterina, Raffaele, additional, Caputo, Marcello, additional, Esposito, Giovanni, additional, Lupi, Alessandro, additional, Mazzarotto, Pietro, additional, Varbella, Fernando, additional, Zaro, Tiziana, additional, Nazzaro, Marco, additional, Rao, Sunil V., additional, van‘t Hof, Arnoud W.J., additional, Omerovic, Elmir, additional, Campo, Gianluca, additional, Uguccioni, Lucia, additional, Tamburino, Corrado, additional, Zavalloni-Parenti, Dennis, additional, Ceravolo, Roberto, additional, Pasquetto, Giampaolo, additional, Mameli, Stefano, additional, Stochino, Maria Letizia, additional, Cremonesi, Alberto, additional, abate, Fabio, additional, Picchi, Andrea, additional, Colangelo, Salvatore, additional, Boccuzzi, Giacomo, additional, Varbella, Ferdinando, additional, Tresoldi, Stefano, additional, Contarini, Marco, additional, Evola, Rosario, additional, Creaco, Manuela, additional, Colombo, Antonio, additional, Chieffo, Alaide, additional, Sciahbasi, Alessandro, additional, Pucci, Edoardo, additional, Romagnoli, Enrico, additional, Moretti, Claudio, additional, Moretti, Luciano, additional, Zimmarino, Marco, additional, Ferrario, Maurizio, additional, Turturo, Maurizio, additional, Bonmassari, Roberto, additional, Penzo, Carlo, additional, Mauro, Ciro, additional, Petronio, Anna Sonia, additional, Gabrielli, Gabriele, additional, Amico, Francesco, additional, Comeglio, Marco, additional, Fresco, Claudio, additional, Van Mieghem, Nicolas, additional, Diletti, Roberto, additional, Regar, Evelyn, additional, Sabaté, Manel, additional, Gómez Hospital, Joan Antoni, additional, Díaz Fernández, José Francisco, additional, and Mainar, Vicente, additional

Published
2017
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11. Prospective multicentre clinical performance evaluation of second and third generation zotarolimus-eluting stents to treat patients with bifurcated coronary lesions

Author

Burzotta, Francesco, Summaria, Francesco, Latib, Azeem, De Vita, Maria, Fantoni, Cecilia, Benedetto, Stefano, Turturo, Maurizio, Larosa, Claudio, Manzoli, Alessandro, and Trani, Carlo

Subjects
Male, Sirolimus, Time Factors, Drug-Eluting Stents, bifurcation lesions, provisional approach, Resolute Integrity stent, Resolute stent, Aged, Coronary Angiography, Coronary Artery Disease, Coronary Vessels, Female, Follow-Up Studies, Humans, Immunosuppressive Agents, Percutaneous Coronary Intervention, Prospective Studies, Prosthesis Design, Treatment Outcome, Radiology, Nuclear Medicine and Imaging, Cardiology and Cardiovascular Medicine, Nuclear Medicine and Imaging, Settore MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARE, Radiology
Abstract

To assess the "real world" clinical outcome of patients with bifurcated lesions undergoing percutaneous coronary intervention with implantation of second and third generations of zotarolimus-eluting stent.Nine Italian centres participated in a prospective multicentre clinical project evaluating the outcome of patients receiving zotarolimus-eluting Resolute stent and Resolute Integrity stents. Patients with bifurcated lesions entered this evaluation. Clinical characteristics and angiographic and procedural details were prospectively recorded. Clinical outcome was prospectively assessed to evaluate the occurrence of major adverse cardiac events (MACE). A total of 577 patients were enrolled. The target lesion was distal left main in 11.1% and left anterior descending artery in 52.8%, and 30.3% of lesions were Medina 1,1,1. At a mean follow-up time of 27.0 ± 13.5 months, the survival free from MACE was 91.8%. Survival free from MACE was similar in patients grouped according to different bifurcated lesion complexity. On the contrary, patients receiving a single stent had better survival free from MACE as compared with those with double stent (P = 0.005). At multivariable analysis, double stenting (but not bifurcated lesion complexity) was found to be a significant predictor of MACE (hazard ratio, 2.52; 95% confidence interval, 1.28-4.94; P = 0.007). Of note, patients receiving the second stent as a bail-out had worse survival free from MACE compared with those who received it as a planned technique (P = 0.045).The treatment of patients with bifurcated lesions with second and third generation zotarolimus-eluting stents is associated with good long-term clinical outcomes. Clinical outcome seems to be independent of lesion complexity, but may be influenced by the stenting technique (single or double stenting as well as elective or bail-out double stenting). © 2015 Wiley Periodicals, Inc.

Published
2014

12. Association of acute kidney injury and bleeding events with mortality after radial or femoral access in patients with acute coronary syndrome undergoing invasive management: secondary analysis of a randomized clinical trial.

Author

Rothenbühler, Martina, Valgimigli, Marco, Odutayo, Ayodele, Frigoli, Enrico, Leonardi, Sergio, Vranckx, Pascal, Turturo, Maurizio, Moretti, Luciano, Amico, Francesco, Uguccioni, Lucia, Contarini, Marco, Gómez-Hospital, Joan Antoni, Mainar, Vicente, Creaco, Manuela, Petronio, Anna Sonia, Cremonesi, Alberto, Tamburino, Corrado, Fresco, Claudio, Bonmassari, Roberto, and Fernández, José Francisco Díaz

Abstract

Aims In the Minimizing Adverse Haemorrhagic Events by TRansradial Access Site and Systemic Implementation of angioX (MATRIX) trial, adults with acute coronary syndrome undergoing coronary intervention who were allocated to radial access had a lower risk of bleeding, acute kidney injury (AKI), and all-cause mortality, as compared with those allocated to femoral access. The mechanism of the mortality benefit of radial access remained unclear. Methods and results We used multistate and competing risk models to determine the effects of radial and femoral access on bleeding, AKI and all-cause mortality in the MATRIX trial and to disentangle the relationship between these different types of events. There were large relative risk reductions in mortality for radial compared with femoral access for the transition from AKI to death [hazard ratio (HR) 0.55, 95% confidence interval (CI) 0.31–0.97] and for the pathway from coronary intervention to AKI to death (HR 0.49, 95% CI 0.26–0.92). Conversely, there was little evidence for a difference between radial and femoral groups for the transition from bleeding to death (HR 1.05, 95% CI 0.42–2.64) and the pathway from coronary intervention to bleeding to death (HR 0.84, 95% CI 0.28–2.49). Conclusion The prevention of AKI appeared predominantly responsible for the mortality benefit of radial as compared with femoral access in the MATRIX trial. There was little evidence for an equally important, independent role of bleeding. View large Download slide View large Download slide [ABSTRACT FROM AUTHOR]

Published
2019
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13. Ticagrelor in patients with diabetes and stable coronary artery disease with a history of previous percutaneous coronary intervention (THEMIS-PCI): a phase 3, placebo-controlled, randomised trial

Author

Bhatt, Deepak L, Steg, Philippe Gabriel, Mehta, Shamir R, Leiter, Lawrence A, Simon, Tabassome, Fox, Kim, Held, Claes, Andersson, Marielle, Himmelmann, Anders, Ridderstråle, Wilhelm, Chen, Jersey, Song, Yang, Diaz, Rafael, Goto, Shinya, James, Stefan K, Ray, Kausik K, Parkhomenko, Alexander N, Kosiborod, Mikhail N, McGuire, Darren K, Harrington, Robert A, Santos, Vladimir, Jain, Ashit, Lendel, Irina, Russo, Michael, Haught, W H, Bouza, Manuel, Gogia, Harinder, Banerjee, Supratim, Kichura, George, Kantaros, Louis, Padron, Francisco, Passi, Rakesh, Stone, Jay, Pursley, Michael, D'Urso, Michael, Gardner, Timothy, Bennett, James, Nour, Khaled, Saini, Satinder, Zhang, Wenwu, Kumbhani, Dharam, Thomas, Dustin, Angiolillo, Dominick, Bertolet, Barry, Roman-Miranda, Amaury, Black, Robert, Manshadi, Ramin, Vaca, Carlos, Blanco, Antonio, Napoli, Mark, Brabham, David, Akyea-Djamson, Ayim, Desai, Pratik, Prasada, Sudhir, Khaira, Ajit, Forgosh, Leslie, Lieber, Ira, Umpierrez, Guillermo, Singal, Dinesh, Londono, Juan, Fraser, Neil, Ruiz, Jose, Vega, Damaris, Rodriguez, Lilia, Brown, Christopher, Syed, Faizullah, Aggarwala, Guarav, Eaves, William, Foster, Michael, Gupta, Dinesh, Avino, David, Asfour, Wail, Tonnessen, Glen, Zhao, Xue-Qiao, Singh, Narendra, Brockmyre, Andrew, Lepor, Norman, Shammas, Nicolas, Blick, David, Hearne, Steven, Prodafikas, John, Carell, Edgar, Izzo, Mark, Karim, Amin, Zakhary, Bosh, Atieh, Mahmoud, Leichter, Steven, Meadows, Charles, Hotchkiss, David, Abu-Fadel, Mazen, Wiseman, Alan, Bander, Jeffrey, Shah, Mahesh, Banerjee, Subhash, Ganim, Ricky, Sopko, Karen, Khan, Misal, Lloret, Ramon, Weirick, Troy, Mehta, Rajendra, Thadani, Udho, Bhargava, Anuj, Kosiborod, Mikhail, Moya, Jaynier, Staniloae, Cezar, Guerra, Yamirka D, Chhabra, Anil, Kosmicki, Douglas, Shaheen, Wassim, Mohammed, Akber, Bitters, J'Cinda, Pattanayak, Jan, Javier, Julian, Srivastava, Sunny, Phillips, Roland, Al-Amin, Jessie, Lillestol, Michael, Simpson, Patrick, Hazan, Lydie, Amin, Amit, Shah, Gopi, Korpas, Denes, Platt, Bruce, Dickert, Jim, Puente, Orlando, Hiotis, Louis, Doyle, Timothy, Rajan, Raj, Meholick, Alan, Gring, Christian, Hage-Korban, Elie, Feldman, Robert, Colfer, Harry, Butman, Samuel, Foster, Malcolm, Hart, Terence, Huling, Randall, Eshaghian, Shervin, Quintana, Ofsman, Cheung, Deanna, Handel, Franklin, Rodriguez, Mara, Suh, David, Gordon, Paul, Pressman, Gregg, Bauer, Michael, French, William, Barettella, Mark, Chatrathi, Sridhar, Suresh, Damodhar, Goldberg, Ronald, Huth, Mark, Younis, Liwa, Rahman, Aref, Mascolo, Richard, Welch, Michelle, Suneja, Randeep, Smith, Stephen, Shurmur, Scott, Agaiby, John, Jingo, Ahmad, Johnston, Janice, Beth, Mary, Vlastaris, Anthony, Kemp, Susan, Taheri, Hamid, Pereira, Edward, Deyoung, Michael, Hawa, Zafir, Smith, Ray, Galski, Thomas, Garas, Samer, Reddy, M, Sharma, Susheel, Hargrove, Joeseph, Treasure, Charles, Emerson, Ronald, Haddad, Tariq, Rohr, Kathryn, Levinson, Larry, Gaona, Raul, Uretsky, Barry, Maheshwari, Hiralal, Lee, Denny, Kinnaman, Stephanie, Singal, Robert, Geohas, Jeffrey, Gigliotti, Osvaldo, Raisinghani, Ajit, Khurana, Charanjit, Hella, Brent, Kelberman, Michael, Voyce, Steven, Singh, Sanjay, Lo, Eric, Singh, Pradeep, Goodfellow, Ross, Fischer, Stuart, Lorraine, Richard, Turner, Traci, Shanes, Jeffrey, Busch, Robert, Broker, Robert, Zaniewski, Michelle, Pounds, Kevin, Debs-Perez, Giselle, Ong, Stephen, Frandsen, Brad, Fullington, Douglas, Jaffrani, Naseem, Khan, Ahtaram, Lee, Marcus, Pouzar, Joe, Revtyak, George, Gonzalez, Julian, Nakhle, Samer, Murillo, Abel, Young, Douglas, Makam, Sashi, Syed, Mushtaq, Woolf, Kevin, Grena, Paul, Alfata, Sarab, Mahal, Sharan, Hoffman, David, Kizhakekuttu, Tinoy, Deering, Joseph, Bhavsar, Janak, Mikesell, Scott, Wilson, William, Wilson, Vance, El, Salah, Spinale, Francis, Kannarkat, Vinod, Rao, Sunder, Hanson, Lenita, Bertsch, John, Gonzalez-Ortiz, Elena, Severino, Norma, Willis, John, Schock, Joel, Bakhtari, Ladan, Gazmuri, Raul, Ansari, Saadat, Hall, Jason, Mehta, Arvind, Shealy, Neal, Zarich, Stuart, Singh, Deovrat, Vora, Kishor, Andrawis, Nabil, Molter, Darron, Maron, David, Cardona, Jose, D'Agostino, Ronald, Arshad, Tamjeed, Samaan, Rodney, Jones, David, Presser, Dale, Heath, John, Green, Sandy, Bittar, George, Henry, Sheldon, Korn, David, Schmedtje, John, Nadar, Venkatesh, Graham, Bruce, Labroo, Ajay, Clavijo, Leonardo, Roseman, Hal, Ledesma, Gilbert, Rosen, Robert, Dor, Isaac, Kirby, William, Sutton, Jennefer, Eder, Frank, Iteld, Bruce, Gomez-Cortes, Jose, Buchbinder, Maurice, Kasper, Joseph, Terrelonge, Antonio, Torres, Gustavo, Jagielo, Ted, Alvarez, Jose, Handelsman, Yehuda, Guillen, Mario, Richwine, Randall, Lewy-Alterbaum, Lorena, Corder, Clinton, Arvind, Moogali, Bolshoun, David, Mikhail, Magdy, Minton, Stephen, Alvarado, Odilon, Abbott, J, Cauthen, Brett, Welter, Ryan, Mintz, Randy, Cox, John, Quick, Annette, Weiss, Melvin, Dy, Johnny, Zebrack, James, Gandelman, Glenn, Hegde, Vinayak, Silver, Marc, DeGregorio, Michele, Lawson, William, Paa, Christopher, Bortnick, Anna, Krolick, Merrill, Sotolongo, Rodolfo, Cheirif, Jorge, Kumar, Priya, Nadar, Venkatesh, Jetty, Preetham, Patel, Ambar, Kruk, Mariusz, Kobielusz-Gembala, Iwona, Rewerska, Barbara, Madrzejewski, Adam, Milewski, Krzysztof, Cygler, Jerzy, Petryka-Mazurkiewicz, Joanna, Jastrzebski, Waldemar, Korecki, Janusz, Fil, Wojciech, Prokopczuk, Janusz, Bochenek, Anna, Wujkowski, Marek, Witek, Robert, Konczakowski, Piotr, Miekus, Pawel, Szczasny, Marcin, Musial, Wlodzimierz, Cymerman, Krzysztof, Lampart, Jacek, Mikosinski, Jacek, Szynal, Slawomir, Fares, Issa, Opolski, Grzegorz, Mazur, Stanislaw, Wozakowska-Kaplon, Beata, Bijata-Bronisz, Renata, Wierucki, Lukasz, Losa, Beata, Drelich, Grzegorz, Konieczny, Marek, Starczewski, Pawel, Pawlowicz, Lidia, Jesionowski, Pawel, Jurowiecki, Jaroslaw, Gniot, Jacek, Czyzycki, Mariusz, Stania, Karol, Kucharczyk-Bauman, Izabela, Busz-Papiez, Benita, Karczmarczyk, Agnieszka, Sudnik, Wanda, Koszek, Alina, Kolodziej, Piotr, Skwarna, Bartosz, Jaramillo, Nicolás, Jankowski, Maciej, Czochra, Wojciech, Kinasz, Leszek, Miklaszewicz, Beata, Stasinska, Teresa, Pluta, Wladyslaw, Basiak, Marcin, Rusicka, Teresa, Niedbal-Yahfouf, Izabela, Popenda, Grazyna, Korzeniak, Romuald, Mirek, Agnieszka, Mariankowski, Rafal, Wojnowski, Lukasz, Korol, Marek, Baszak, Jacek, Podolec, Piotr, Piesiewicz, Wojciech, Zurakowski, Aleksander, Luengas, Carlos, Skura, Marek, Pilecki, Piotr, Majchrzak, Piotr, Krzyzagórska, Ewa, Drozd, Marcin, Kaczmarek, Barbara, Sliwinska, Teresa, Zelazowska, Katarzyna, Sztembis, Rafal, Landa, Katarzyna, Matyszczak-Toniak, Lidia, Strojek, Krzysztof, Piepiorka, Marek, Malinowski, Robert, Górska, Maria, Stolarczyk-Sowa, Edyta, Romanowski, Leszek, Zinka, Elzbieta, Reszka, Zygfryd, Skierkowska, Joanna, Uzunow, Anna, Laskowska-Derlaga, Ewa, Puntus, Ekaterina, Kosmacheva, Elena D, Koziolova, Natalia, Pavlov, Prokhor, Supryadkina, Tatiana, Didenko, Yury, Kopylov, Philipp, Kazakov, Andrei, Aksentiev, Sergei, Vishneva, Elena, Repin, Alexey, Smolenskaya, Olga, Mantserova, Olga, Khrustalev, Oleg, Privalova, Elena, Konstantinov, Vladimir, Boldueva, Svetlana, Ezhov, Andrey, Chernyavsky, Alexander, Kamalov, Gadel, Galyavich, Albert, Zubeeva, Galina, Nechaeva, Galina, Shustov, Sergey, Dzhaiani, Nino, Treshkur, Tatiana, Osokina, Nataliya, Panov, Alexey, Shutemova, Elena, Makukhin, Valeriy, Kropotina, Tatiana, Tsyba, Larisa, Karpov, Yuri, Sizova, J M, Ballyuzek, Marina, Tarasov, Nikolay, Demchenko, Elena, Barbarash, Olga, Moiseev, Valentin, Markov, Valentin, Kuznetsov, Vadim, Viktorova, Inna, Sergienko, Igor, Ermoshkina, Lyudmila, Khasanov, Niyaz, Khlevchuk, Tatiana, Baglikov, Andrey, Shalaev, Sergey, Zonova, Elena, Reznik, Elena, Haisheva, Larisa, Morugova, Tatyana, Lomakin, Nikita, Vishnevsky, Alexander, Shvarts, Yuri, Magnitskaya, Olga, Mikhailusova, Marina, Pavlysh, Elena, Libov, Igor, Zateyschikova, Anna, Kostenko, Victor, Edin, Anton, Khovaeva, Yaroslava, Zakharov, Konstantin, Stryuk, Raisa, Khirmanov, Vladimir, Kanorskiy, Sergey, Yakushin, Sergey, Barabashkina, Anna, Li, Hongwei, Zhao, Qiang, Zhang, Jian, Ma, Jianhua, He, Yong, Luo, Ming, Zhang, Aidong, Zhang, Ningru, Chai, Yingru, Ma, Genshan, Wang, Hao, Liu, Zhigang, He, Lanjie, Song, Zhifang, Dong, Xiaolin, Tao, Liang, Li, Zhanquan, Su, Xi, Kong, Xiangqing, Niu, Heping, Ge, Junbo, Luo, Zhurong, Huang, Wenjun, Peng, Daoquan, Yuan, Zuyi, Milanova, Maria, Tenev, Doncho, Gogov, Antoni, Karageorgiev, Dimitar, Kolchev, Todor, Rusev, Nikolay, Georgieva, Nikolina, Kondov, Rumen, Rusinov, Veselin, Petrov, Ivo, Stanchev, Georgi, Konteva, Mariana, Dincheva, Adriana, Yaneva, Zdravka, Vatova, Ralitsa, Ilieva, Katya, Runev, Nikolai, Kolomanov, Borislav, Petrov, Ivan, Iliev, Nikolay, Tisheva, Snezhanka, Chompalova, Boryana, Tokmakova, Maria, Raev, Dimitar, Byanov, Kolyo, Markov, Dimitar, Mihov, Lenko, Mihov, Atanas, Milcheva, Nora, Minchev, Milen, Mollov, Mihail, Borisov, Borislav, Tihchev, Tihomir, Karakolev, Venelin, Dimov, Bojidar, Georgiev, Svetoslav, Smilov, Lachezar, Koo, Bon K, Ahn, Taehoon, Hong, Soon J, Yoon, Junghan, Oh, Seok K, Jeong, Myung H, Kim, Doo-Il, Chang, Kiyuk, Kim, Weon, Hahn, Joo-Yong, Cha, Kwang S, Lee, Jung-Hee, Choi, Si-Wan, Nam, Chang-Wook, Chae, In-Ho, Park, Yong H, Tahk, Seung-Jea, Shin, Won-Yong, Chae, Jei-Keon, Kim, Byung J, Bae, Jang-Whan, Park, Woo J, Rha, Seung W, Choi, Young J, Hwang, Jin-Yong, Park, Hun S, Baracioli, Luciano, Guimaraes, Fabio, Vasconcellos, Eduardo, Saraiva, José, Pereira, Adamastor, Santos, Queulla, Rossi, Paulo, Maia, Lilia, Madeira, Miguel, Pereira, Marcio, Botelho, Roberto, Reis, Gilmar, Eliaschewitz, Freddy, Borges, Joao, Nascimento, Carlos, Fortes, Jose A, de Souza, Weimar, Pimentel, Pedro, Hissa, Miguel, Franchetti, Marcos, Precoma, Dalton, Ortiz, Costantino, Hernandes, Mauro, Saporito, Wladmir, dos Santos, Fabio R, Kormann, Adrian, Neuenschwander, Fernando, Dutra, Oscar, Rassi, Nelson, Tanajura, Luiz, Souza, Juliana, Junior, Delcio S, Leaes, Paulo, Forte, Adriana, Bonansea, Teresa C, Marin, Jose, Machado, Bruno, Cerqueira, Maria J, Silva, Frederico, Michalaros, Yorghos, Manenti, Euler, Cercato, Cintia, Figueiredo, Estevao, Liu, Ming-En, Wang, Yi-Chih, Lee, Tsung-Ming, Fang, Chih, Wu, Yen-Wen, Ueng, Kwo-Chang, Sheu, Huey-Herng, Lai, Wen T, Hsieh, I-Chang, Chen, Zhih-Cherng, Lee, Mu-Jang, Chiang, Chern, Shyu, Kou-Gi, Hsia, Chien-Hsun, Mar, Guang-Yuan, Chan, Shih-Hung, Wu, Chih-Cheng, Tseng, Wei-Kung, Chang, Kuan-Cheng, Yeh, Hung-I, Wang, Ji-Hung, Hou, Charles, Sorokina, Inna, Dolzhenko, Maryna, Horoshko, Olha, Karpenko, Oleksandr, Rudenko, Leonid, Vakaliuk, Igor, Kulyk, Anna, Levchenko, Olena, Prokhorov, Oleksandr, Reshotko, Dmytro, Sorokivskyy, Mykhaylo, Velichko, Nataliia, Maslovskyi, Valentyn, Teliatnikova, Zinaida, Dotsenko, Sergiy, Krakhmalova, Olena, Kraiz, Igor, Zharinova, Viktoria, Bula, Larysa, Kaydashev, Igor, Molodtsov, Valeriy, Rasputina, Lesya, Pidlisna, Viktoriya, Lysunets, Olena, Kravchenko, Anatoliy, Glushko, Liubomyr, Khomazyuk, Tetyana, Svyshchenko, Yevgeniya, Parkhomenko, Oleksandr, Mankovsky, Boris, Abrahamovych, Orest, Yagensky, Andriy, Stanislavchuk, Mykola, Vasilyeva, Larisa, Sokolova, Liubov, Sychov, Oleg, Tseluyko, Vira, Kyrychenko, Igor, Rishko, Mykola, Furkalo, Sergiy, Gallo, Richard, Bertrand, Olivier, Mehta, Shamir, Constance, Christian, Sussex, Bruce, Zadra, Remo, Kouz, Simon, Chehayeb, Raja, Pandey, Amritanshu, Dion, Danielle, Bailey, Gordon, Hill, Laurie, Ramanathan, Krishnan, Dorsch, Micha, Nanji, Alykhan, Babapulle, Mohan, Montigny, Martine, Gosselin, Gilbert, Dehghani, Payam, Rupka, Dennis, Le May, Michel, Pichette, Francis, St-Maurice, Francois, Teefy, Patrick, Mansour, Samer, Kassam, Saleem, Cheung, Stephen, Siega, Anthony D, O'Keefe, Dennis, Sabbah, Eric, Bell, Alan, Chouinard, Guy, Wong, Brian, Miller, Mark, Gaudet, Daniel, Lachance, Pierre, Bata, Iqbal, Petrella, Robert, Gossard, Denis, Dumas, Richard, Ing, Douglas, Boyrazian, Hagop, Bessoudo, Ricardo, Huynh, Thao T, Hart, Randy, Belle-Isle, Jasmin, Shukla, Dinkar, Kelly, Allan, Mazza, Giuseppe, Cha, James, Henein, Sam, Frechette, Andre, Vizel, Saul, Liutkus, Joanne F, O'Mahony, Michael, Halperin, Frank, Kooy, Jacobus, Graham, John, Bailey, Allan, Wojcik, Ronald, Wilderman, Igor, Turi, Tibor, Motyovszki, Ákos, Merkely, Béla, Király, Csaba, Andrássy, Péter, Sárszegi, Zsolt, Fülöp, Tibor, Zilahi, Zsolt, Édes, István, Papp, Andras, Müller, Gábor, Czigány, Anna, Zólyomi, Szilárd, Korányi, László, Takács, János, Juhász, Ferenc, Benczur, Bela, Kancz, Sándor, Földi, András, Nagy, András C, Bakai, Judit, Greschik, István, Püski, László, Nagy, László, Kirschner, Róbert, Kuchar, Roman, Hajek, Petr, Busak, Ladislav, Michalik, Daniel, Matyasek, Ivo, Marusincova, Ivana, Kucera, Dusan, Jerabek, Ondrej, Honkova, Michaela, Dedek, Vratislav, Rihacek, Ivan, Kos, Pavel, Slaby, Josef, Machkova, Martina, Zidkova, Eva, Elbl, Lubomir, Grunfeldova, Hana, Carda, Jiri, Mrozek, Vladimir, Maly, Jiri, Milkovic, Richard, Malecha, Jan, Skalicka, Hana, Oral, Ivo, Krcova, Eva, Lisa, Libor, Belohlavek, Jan, Miklik, Roman, Cermak, Ondrej, Bednarova, Jana, Peroutka, Zdenek, Spinar, Jindrich, Wilke, Andreas, Appel, Karl-Friedrich, Taggeselle, Jens, Förster, Andreas, Toursarkissian, Nicole, Schmidt, Ekkehard, Bott, Jochen, Al-Zoebi, Ayham, Hennig, Dirk, Fischer, Sabine, Schön, Norbert, Sauter, Joachim, Simonis, Gregor, Nischik, Ruth, Rieker, Werner, Schenkenberger, Isabelle, Behnke, Thomas, Klausmann, Gerhard, Jeserich, Michael, Trenk, Dietmar, Weigmann, Ingo, Reuter, Hannes, Rummel, Reinhard, von Münchhausen, Candy, von Engelhardt, Charlotte, Horibe, Eishun, Shibasaki, Taro, Sato, Tomohiko, Kakuta, Tsunekazu, Michishita, Ichiro, Tan, Michinao, Ishiki, Ryoji, Aoyama, Takahiko, Higashiue, Shinichi, Niijima, Yawara, Idogaki, Akira, Hasegawa, Toru, Kiyosue, Arihiro, Tomobuchi, Yoshiaki, Kawamitsu, Katsunori, Kawasaki, Satsuki, Hata, Yoshiki, Fukui, Kazuki, Seki, Kozaburo, Takenaka, Takashi, Abe, Mitsuru, Utsu, Noriaki, Oono, Atsuyuki, Mitsuo, Kazuhisa, Sueyoshi, Atsushi, Hirohata, Atsushi, Tsujimoto, Mitsuru, Ueda, Osamu, Takase, Shinichi, Suzuki, Masahiro, Sakuragi, Satoru, Yamamoto, Fumi, Fujimoto, Noritaka, Kakinoki, Shigeo, Sugiura, Tatsushi, Sugino, Hiroshi, Nakamura, Toshihiro, Goto, Shinya, Kadokami, Toshiaki, Uehara, Hiroki, Ono, Masahiro, Yokoya, Koichi, Koike, Akihiro, Komatsu, Sei, Sonoda, Masahiro, Ueno, Hideki, Doi, Tomofumi, Takagi, Yuichiro, Fujimoto, Kazuteru, Eki, Yutaka, Okubo, Munenori, Sasaki, Kenichiro, van Eck, Martijn, Ronner, Eelko, The, Salem, van de Wal, Ruud, Nierop, Pieter, de Nooijer, Cornelis, The, Salem, The, Salem, Werner, Henri, Westendorp, Iris, van der Zwaan, Coen, Crijns, Hendrikus, Cornel, Jan H, Strikwerda, Sipke, Bos, Robert, de Melker, Edwin, Kuijper, Adrianus, Louwerenburg, Hans, Plomp, Jacobus, Dantzig, Jan-Melle, Prins, Francisco, van Kesteren, Henricus, Willems, Frank, Amoroso, Giovanni, Carnero, Gabriela, Duronto, Ernesto, Besada, Diego, Chacon, Carolina, Zangroniz, Pedro, Solis, Silvana, Liberman, Alberto, Sernia, Virginia, Alvarisqueta, Andres, Maffei, Laura, Vilamajo, Oscar G, García, Celso, Sicer, Maximiliano, Muntaner, Juan, Bordonava, Anselmo, Albisu, Juan, Zanini, Alejandra, Rista, Lucas, Hominal, Miguel, Estrada, José N, Prado, Aldo, Gosparini, Diego M, Schiavi, Beatriz, Castillo, Armando G, Ruíz, José G, Martinez, Guillermo R, López, Víctor G, Rosas, Enrique L, Lopez, Gabriel R, Cantu, Elias G, de los Ríos Ibarra, Manuel, Padilla, Francisco P, Carrasco, Jose P, Carrillo, Luis V, García, Joel D, Askar, Alfredo N, Salinas, Carlos A, Gamba, Marco A, Sanchez, Carlos G, Cantú, Arnulfo G, Sánchez, Raul V, Madrigal, Jaime C, Urbano, Rafael H, Romo, Andrés Í, González Juanatey, José R, Racugno, Paolo, Fillat, Angel C, de la Torre Hernández, José M, Peláez, Juan A, Cortada, Jorge B, Pavia, Pablo G, Navarro, Manuel J, Asenjo, Roberto M, Díaz, Francisco F, Peligero, Eduard B, Manterola, Fernando A, Ortiz, Antonio F, Mediavilla García, Juan D, Ortuño, Francisco M, Vera, Tomás R, González, Alfonso S, Viñas, Jaime A, Fernández Portales, Francisco J, Mayordomo, Petra S, Ojeda, Francisco B, Domínguez, Antonio R, González, Rosa S, Guerrero, Diego B, Ruiz Nodar, Juan M, Marimon, Xavier G, Margáez, José G, Aguilera, Roberto M, Díaz Fernández, José F, Zamorano Gómez, José L, González, Vicente B, del Blanco, Bruno G, Pérez, Ignacio P, Moreno, Mercé R, Ereño, Ainhoa R, García Lledó, José A, Prieto, Juan, Villablanca, Alex, Raffo, Carlos, Pincetti, Christian, Conejeros, Carlos, Roman, Oscar, Rodriguez, Manuel, Varleta, Paola, Goldberg, Cindy, Sandoval, Jorge, Arriagada, German, Leon, Lucio, Potthoff, Sergio, Cobos, Jorge, Figueroa, Christian, Makotoko, Ellen, Fourie, Nyda, Burgess, Lesley, Nortje, Hendrik, Theron, Rust, Pillai, Perumal, Ranjith, Naresh, Trokis, Julien, Pillay, Soobramoney, Reddy, Jeevren, Nunkoo, Theema, Kapp, Cornelia, Urbach, Dorothea, Distiller, Lawrence, Horak, Adrian, van Zyl, Louis, Coetzee, Kathleen, Punt, Zelda, Bayat, Junaid, Dawood, Saleem, Mitha, Ismail, Padayachee, Trevenesan, Hoosen, Farzana, Dalby, Anthony, Prabhavathi, Gowdaiah, Prakash, Mehta, Vimal, Chag, Milan, Gadkari, Milind, Ramamurthee, Kannaiyan, Das, Asit, Sawhney, Jitendra S, Banerjee, Suvro, Sathe, Prachee, Adhyapak, Srilakshmi, Nguyen, Tuan, Pham, Vinh, Do, Huan, Nguyen, Anh, Nguyen, Hien, Truong, Binh, Jamil-Copley, Shahnaz, Lang, Chim, Pell, Alastair, Zaman, Azfar, Storey, Robert, Swanson, Neil, Smith, Simon, Sharman, David, Braganza, Denise, Hammond, Peter, Moriarty, Andrew, Bain, Stephen, Pye, Maurice, Sharp, Andrew, Blagden, Mark, Randeva, Harpal, Myhill, Timothy, Viswanathan, Girish, Keeling, Philip, Clifford, Piers, Saxena, Manish, Lyons, Kristopher, McMurray, John, Jaafar, Feeroz, Murphy, Clare, Cartwright, Simon, Abouglila, Kamal, Antalik, Lubomir, Krajci, Peter, Urban, Miroslav, Fazekas, Frantisek, Pella, Daniel, Koleny, Daniel, Vykoukalova, Tatiana, Macek, Vladimir, Vinanska, Daniela, Jamriskova, Livia, Such, Slavomir, Fulop, Peter, Farsky, Stefan, Bugan, Viliam, Strbova, Jaroslava, Micko, Karol, Palka Jr, Juraj, Sivak, Vladimir, Kristensen, Dalby, Refsgaard, Jens, Holmvang, Lene, Dixen, Ulrik, Nielsen, Henrik, Egstrup, Kenneth, Jensen, Lisette O, Sykulski, Roman, Rasmussen, Ole, Andries, Alin, Luckow, Anders, Nielsen, Gitte, Sørensen, Torben, Wongvipaporn, Chaiyasith, Chamnarnphol, Noppadol, Srimahachota, Suphot, Sansanayudh, Nakarin, Kuanprasert, Srun, Tresukosol, Damras, Sookananchai, Bancha, Kanadasi, Mehmet, Ozcan, Turkay, Kucuk, Murathan, Ongen, Zeki, Okuyan, Ertugrul, Arat, Alev, Acikel, Sadik, Yalcin, Ahmet, Guray, Umit, Ceyhan, Ceyhun, Ozer, Necla, Arslan, Sakir, Angerås, Oskar, Johnston, Nina, Weiderman, Ann-Charlotte, Bandh, Stellan, Hansen, Ole, Larnefeldt, Hans, Kusiak, Dawid, Lindholm, Carl-Johan, Hedman, Anders, Erlinge, David, Curiac, Dan, Lundman, Pia, Zucconi-Mazzini, Roberto, Aladellie, Layth, Jensen, Jens, Verwerft, Jan, Vrolix, Mathias, Faes, Dirk, Striekwold, Harry, Sinnaeve, Peter, Timmermans, Patrick, Guedes, Antoine, Delforge, Marc, Nimmegeers, Jan, Stammen, Francis, Buysschaert, Ian, Hoffer, Etienne, Hollanders, Geert, Vervoort, Geert, Coussement, Patrick, de Maeseneire, Stefan, Janssens, Luc, Gravdal, Stein A, Risberg, Knut, Gullestad, Lars, Hofseth, Ola D, Nilsen, Dennis, Lappegård, Knut T, van den Heuvel, Christian, Gibbs, Charlotte, Khusrawi, Alamdar, Arora, Satish, Tomala, Tadeusz, Kjærnli, Thorbjørn, Berg-Johansen, Jan, Hagemeier, Robert, Skjelvan, Gunnar, Colquhoun, David, Amerena, John, Morbey, Claire, Hammett, Christopher, Dart, Anthony, Lehman, Ronald, Hamilton, Andrew, Worthley, Matthew, Purnell, Peter, Whelan, Alan, MacIsaac, Richard, Arya, Ktut, Linjawi, Sultan, Proietto, Joseph, Prasad, Lakshman, Rodriguez, Aldo, Godoy, Armando, Rodriguez, Victor, Berrospi, Percy, Chavez, Carlos, Negron, Sandra, Heredia, Javier, Medina, Felix, Manrique, Helard, Cabrera, Walter, Cordova, Fernando, Quinteros, Trinidad, Haro, Jaime M, Regalado, Susana, Guitton, Javier, Arbanil, Hugo, Pansieri, Michel, Decoulx, Eric, Goube, Pascal, de Labriolle, Axel, Labeque, Jean N, Range, Gregoire, Cottin, Yves, Montalescot, Gilles, Cayla, Guillaume, Danchin, Nicolas, Angoulvant, Denis, Ferrario, Emile, Elbaz, Meyer, Dubreuil, Olivier, Steg, Philippe G, Fontaine, Caroline, Sorbets, Emmanuel, Omer, Hafiz, Al-Saif, Shukri, Al-Faleh, Hussam, Al-Shehri, Abdullah, Alshehri, Halia, Bazari, Rasha, Hei, Pak, Ying, Man, Chan, Michael, Wong, Michelle, Ma, Ronald, Siu, Shing C, Tsang, Chiu C, Ferrario, Maurizio, Assanelli, Emilio, Senni, Michele, Piatti, Piermarco, Calabrò, Paolo, Urbinati, Stefano, Michisanti, Massimo, Varbella, Ferdinando, de Cosmo, Salvatore, Trevisan, Roberto, Bellotti, Sandro, Di Pasquale, Giuseppe, Bongo, Angelo S, Uguccioni, Massimo, Mannucci, Edoardo, Mauro, Ciro, Ragonese, Mauro, Fresco, Claudio, Turturo, Maurizio, Marcucci, Rossella, Lievano Triana, Manuel J, Arana, Camilo, Accini, Jose, Botero, Rodrigo, Muzyk-Osikowicz, Marlena, Dada, Fredy T, Vallejo, Gregorio S, Manzur, Fernando, Isaza, Daniel, Molina, Dora, Mesa, Juan G, Quintero, Alvaro, Nyman, Kai, Mäkelä, Jyrki, Strand, Jorma, Nieminen, Sakari, Taurio, Jyrki, Kuusela, Matti, Valle, Timo, Pietilä, Mikko, Kekki, Sakari, Strandberg, Timo, Klutstein, Marc, Greenberg, Gabriel, Rozenman, Yoseph, Chorin, Ehud, Roguin, Ariel, Lewis, Basil, Bashkin, Amir, Tan, Edgar, Prado, Jose P, Ferrolino, Arthur, Babilonia, Noe, Barbas, Benny, Matiga, Generoso, Coching, Raul M, Drexel, Heinz, Brath, Helmut, Schnack, Christoph, Hanusch, Ursula, Fließer-Görzer, Evelyn, Paulweber, Bernhard, Ebenbichler, Christoph, Prager, Rudolf, Huber, Kurt, Wolzt, Michael, Auer, Johann, Berger, Rudolf, Schernthaner, Gerit-Holger, Stanciulescu, Gabriela, Creteanu, Mihai, Spiridon, Marilena, Dobreanu, Viorica, Vinereanu, Dragos, Iosipescu, Laura C, Istratoaie, Octavian, Coman, Ioan, Militaru, Constantin, Cinteza, Mircea, Bhatt, Deepak L, Fox, Kim, Harrington, Robert A, Leiter, Lawrence A, Mehta, Shamir R, Simon, Tabassome, Andersson, Marielle, Himmelmann, Anders, Steg, Philippe G, Diaz, Rafael, Amerena, John, Huber, Kurt, Sinnaeve, Peter R, Nicolau, José C, Kerr Saraiva, José F, Petrov, Ivo, Leiter, Lawrence A, Mehta, Shamir R, Corbalán, Ramón, Ge, Junbo, Zhao, Qiang, Botero, Rodrigo, Widimský, Petr, Kristensen, Steen D, Hartikainen, Juha, Danchin, Nicolas, Darius, Harald, Tse, Hung F, Kiss, Robert G, Pais, Prem, Lev, Eli, de Luca, Leonardo, Goto, Shinya, Ramos López, Gabriel A, Cornel, Jan H, Kontny, Frederic, Medina, Felix, Babilonia, Noe A, Opolski, Grzegorz, Vinereanu, Dragos, Zateyshchikov, Dmitry A, Ruda, Mikhail, Elamin, Omer, Kovář, František, Dalby, Anthony J, Jeong, Myung H, Bueno, Héctor, James, Stefan K, Chiang, Chern-En, Tresukosol, Damras, Ongen, Zeki, Ray, Kausik K, Parkhomenko, Alexander, McGuire, Darren K, Kosiborod, Mikhail N, Nguyen, Tuan Q, Andersson, Marielle, Chen, Jersey, Himmelmann, Anders, Leonsson-Zachrisson, Maria, and Ridderstråle, Wilhelm

Abstract

Patients with stable coronary artery disease and diabetes with previous percutaneous coronary intervention (PCI), particularly those with previous stenting, are at high risk of ischaemic events. These patients are generally treated with aspirin. In this trial, we aimed to investigate if these patients would benefit from treatment with aspirin plus ticagrelor.

Published
2019
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14. Prospective multicentre clinical performance evaluation of second and third generation zotarolimus-eluting stents to treat patients with bifurcated coronary lesions

Author

Burzotta, Francesco, primary, Summaria, Francesco, additional, Latib, Azeem, additional, De Vita, Maria, additional, Fantoni, Cecilia, additional, Benedetto, Stefano, additional, Turturo, Maurizio, additional, Larosa, Claudio, additional, Manzoli, Alessandro, additional, and Trani, Carlo, additional

Published
2015
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16. TCT-286 Rates of Percutaneous Coronary Revascularization in Morphological- vs Functional-Guided Arms of the INTERCLIMA (Interventional Strategy for Non-Culprit Lesions With Major Vulnerability Criteria Identified by OCT in Patients With ACS) Randomized Controlled Trial: Preliminary Data

Author

Biccirè, Flavio Giuseppe, carmine musto, ugo limbruno, Fabbiocchi, Franco, Turturo, Maurizio, Boi, Alberto, Cassano, Francesco, Calligaris, Giuseppe, Benenati, Stefano, Budassi, Simone, Cesario, Vincenzo, Bortone, Alessandro, Porto, Italo, Arbustini, Eloisa, Kedhi, Elvin, Alfonso, Fernando, Raber, Lorenz, and Prati, Francesco

Subjects
*INTRA-abdominal hypertension, *PATIENTS, *MYOCARDIAL infarction
Published
2022
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17. Radial versus femoral access and bivalirudin versus unfractionated heparin in invasively managed patients with acute coronary syndrome (MATRIX): final 1-year results of a multicentre, randomised controlled trial

Author

Marco Valgimigli, Enrico Frigoli, Sergio Leonardi, Pascal Vranckx, Martina Rothenbühler, Matteo Tebaldi, Ferdinando Varbella, Paolo Calabrò, Stefano Garducci, Paolo Rubartelli, Carlo Briguori, Giuseppe Andó, Maurizio Ferrario, Ugo Limbruno, Roberto Garbo, Paolo Sganzerla, Filippo Russo, Marco Nazzaro, Alessandro Lupi, Bernardo Cortese, Arturo Ausiello, Salvatore Ierna, Giovanni Esposito, Giuseppe Ferrante, Andrea Santarelli, Gennaro Sardella, Nicoletta de Cesare, Paolo Tosi, Arnoud van 't Hof, Elmir Omerovic, Salvatore Brugaletta, Stephan Windecker, Dik Heg, Peter Jüni, Gianluca Campo, Lucia Uguccioni, Corrado Tamburino, Patrizia Presbitero, Dennis Zavalloni-Parenti, Fabio Ferrari, Roberto Ceravolo, Fabio Tarantino, Giampaolo Pasquetto, Gavino Casu, Stefano Mameli, Maria Letizia Stochino, Pietro Mazzarotto, Alberto Cremonesi, Francesco Saia, Giovanni Saccone, Fabio Abate, Andrea Picchi, Roberto Violini, Salvatore Colangelo, Giacomo Boccuzzi, Vincenzo Guiducci, Carlo Vigna, Antonio Zingarelli, Andrea Gagnor, Tiziana Zaro, Simone Tresoldi, Pietro Vandoni, Marco Contarini, Armando Liso, Antonio Dellavalle, Salvatore Curello, Fabio Mangiacapra, Rosario Evola, Cataldo Palmieri, Camillo Falcone, Francesco Liistro, Manuela Creaco, Antonio Colombo, Alaide Chieffo, Andrea Perkan, Stefano De Servi, Dionigi Fischetti, Stefano Rigattieri, Alessandro Sciahbasi, Edoardo Pucci, Enrico Romagnoli, Claudio Moretti, Luciano Moretti, Raffaele De Caterina, Marcello Caputo, Marco Zimmarino, Ezio Bramucci, Emilio Di Lorenzo, Maurizio Turturo, Roberto Bonmassari, Carlo Penzo, Bruno Loi, Ciro Mauro, Anna Sonia Petronio, Gabriele Gabrielli, Antonio Micari, Flavia Belloni, Francesco Amico, Marco Comeglio, Claudio Fresco, Isala Klinieken, Nicolas Van Mieghem, Roberto Diletti, Evelyn Regar, Manel Sabaté, Joan Antoni Gómez Hospital, José Francisco Díaz Fernández, Vicente Mainar, Jose Maria de la Torre Hernandez, Valgimigli, Marco, Frigoli, Enrico, Leonardi, Sergio, Vranckx, Pascal, Rothenbühler, Martina, Tebaldi, Matteo, Varbella, Ferdinando, Calabrò, Paolo, Garducci, Stefano, Rubartelli, Paolo, Briguori, Carlo, Andó, Giuseppe, Ferrario, Maurizio, Limbruno, Ugo, Garbo, Roberto, Sganzerla, Paolo, Russo, Filippo, Nazzaro, Marco, Lupi, Alessandro, Cortese, Bernardo, Ausiello, Arturo, Ierna, Salvatore, Esposito, Giovanni, Ferrante, Giuseppe, Santarelli, Andrea, Sardella, Gennaro, de Cesare, Nicoletta, Tosi, Paolo, van 't Hof, Arnoud, Omerovic, Elmir, Brugaletta, Salvatore, Windecker, Stephan, Heg, Dik, Jüni, Peter, Cardiologie, RS: CARIM - R2.01 - Clinical atrial fibrillation, MUMC+: MA Med Staf Spec Cardiologie (9), Campo, Gianluca, Uguccioni, Lucia, Tamburino, Corrado, Presbitero, Patrizia, Zavalloni-Parenti, Denni, Ferrari, Fabio, Ceravolo, Roberto, Tarantino, Fabio, Pasquetto, Giampaolo, Casu, Gavino, Mameli, Stefano, Stochino, Maria Letizia, Mazzarotto, Pietro, Cremonesi, Alberto, Saia, Francesco, Saccone, Giovanni, Abate, Fabio, Picchi, Andrea, Violini, Roberto, Colangelo, Salvatore, Boccuzzi, Giacomo, Guiducci, Vincenzo, Vigna, Carlo, Zingarelli, Antonio, Gagnor, Andrea, Zaro, Tiziana, Tresoldi, Simone, Vandoni, Pietro, Contarini, Marco, Liso, Armando, Dellavalle, Antonio, Curello, Salvatore, Mangiacapra, Fabio, Evola, Rosario, Palmieri, Cataldo, Falcone, Camillo, Liistro, Francesco, Creaco, Manuela, Colombo, Antonio, Chieffo, Alaide, Perkan, Andrea, De Servi, Stefano, Fischetti, Dionigi, Rigattieri, Stefano, Sciahbasi, Alessandro, Pucci, Edoardo, Romagnoli, Enrico, Moretti, Claudio, Moretti, Luciano, De Caterina, Raffaele, Caputo, Marcello, Zimmarino, Marco, Bramucci, Ezio, Di Lorenzo, Emilio, Turturo, Maurizio, Bonmassari, Roberto, Penzo, Carlo, Loi, Bruno, Mauro, Ciro, Petronio, Anna Sonia, Gabrielli, Gabriele, Micari, Antonio, Belloni, Flavia, Amico, Francesco, Comeglio, Marco, Fresco, Claudio, Klinieken, Isala, Van Mieghem, Nicola, Diletti, Roberto, Regar, Evelyn, Sabaté, Manel, Gómez Hospital, Joan Antoni, Díaz Fernández, José Francisco, Mainar, Vicente, and de la Torre Hernandez, Jose Maria

Subjects
Male, Prasugrel, medicine.medical_treatment, MONOTHERAPY, Myocardial Infarction, 030204 cardiovascular system & hematology, Coronary Angiography, ANGIOGRAPHY, law.invention, 0302 clinical medicine, Randomized controlled trial, law, Bivalirudin, ARTERY-DISEASE, 030212 general & internal medicine, Myocardial infarction, 610 Medicine & health, Medicine (all), SITE, 2017 ESC, PCI, General Medicine, Hirudins, Middle Aged, Clopidogrel, Recombinant Proteins, Prosthesis Failure, Stroke, Femoral Artery, Acute Coronary Syndrome, Aged, Anticoagulants, Antithrombins, Female, Hemorrhage, Heparin, Humans, Mortality, Peptide Fragments, Percutaneous Coronary Intervention, Perioperative Care, Platelet Glycoprotein GPIIb-IIIa Complex, Stents, Radial Artery, Cardiology, Ticagrelor, INTERVENTION, medicine.drug, Acute coronary syndrome, medicine.medical_specialty, ACUTE MYOCARDIAL-INFARCTION, 03 medical and health sciences, Internal medicine, medicine, METAANALYSIS, business.industry, Percutaneous coronary intervention, medicine.disease, business
Abstract

Summary Background The Minimizing Adverse Haemorrhagic Events by Transradial Access Site and Systemic Implementation of Angiox (MATRIX) programme was designed to assess the comparative safety and effectiveness of radial versus femoral access and of bivalirudin versus unfractionated heparin with optional glycoprotein IIb/IIIa inhibitors in patients with the whole spectrum of acute coronary syndrome undergoing invasive management. Here we describe the prespecified final 1-year outcomes of the entire programme. Methods MATRIX was a programme of three nested, randomised, multicentre, open-label, superiority trials in patients with acute coronary syndrome in 78 hospitals in Italy, the Netherlands, Spain, and Sweden. Patients with ST-elevation myocardial infarction were simultaneously randomly assigned (1:1) before coronary angiography to radial or femoral access and to bivalirudin, with or without post-percutaneous coronary intervention infusion or unfractionated heparin (one-step inclusion). Patients with non-ST-elevation acute coronary syndrome were randomly assigned (1:1) before coronary angiography to radial or femoral access and, only if deemed eligible to percutaneous coronary intervention after angiography (two-step inclusion), entered the antithrombin type and treatment duration programmes. Randomisation sequences were computer generated, blocked, and stratified by intended new or current use of P2Y12 inhibitor (clopidogrel vs ticagrelor or prasugrel), and acute coronary syndrome type (ST-elevation myocardial infarction, troponin-positive, or troponin-negative non-ST-elevation acute coronary syndrome). Bivalirudin was given as a bolus of 0·75 mg/kg, followed immediately by an infusion of 1·75 mg/kg per h until completion of percutaneous coronary intervention. Heparin was given at 70–100 units per kg in patients not receiving glycoprotein IIb/IIIa inhibitors, and at 50–70 units per kg in patients receiving glycoprotein IIb/IIIa inhibitors. Clinical follow-up was done at 30 days and 1 year. Co-primary outcomes for MATRIX access and MATRIX antithrombin type were major adverse cardiovascular events, defined as the composite of all-cause mortality, myocardial infarction, or stroke up to 30 days; and net adverse clinical events, defined as the composite of non-coronary artery bypass graft-related major bleeding, or major adverse cardiovascular events up to 30 days. The primary outcome for MATRIX treatment duration was the composite of urgent target vessel revascularisation, definite stent thrombosis, or net adverse clinical events up to 30 days. Analyses were done according to the intention-to-treat principle. This trial is registered with ClinicalTrials.gov, number NCT01433627. Findings Between Oct 11, 2011, and Nov 7, 2014, we randomly assigned 8404 patients to receive radial (4197 patients) or femoral (4207 patients) access. Of these 8404 patients, 7213 were included in the MATRIX antithrombin type study and were randomly assigned to bivalirudin (3610 patients) or heparin (3603 patients). Patients assigned to bivalirudin were included in the MATRIX treatment duration study, and were randomly assigned to post-procedure infusion (1799 patients) or no post-procedure infusion (1811 patients). At 1 year, major adverse cardiovascular events did not differ between patients assigned to radial access compared with those assigned to femoral access (14·2% vs 15·7%; rate ratio 0·89, 95% CI 0·80–1·00; p=0·0526), but net adverse clinical events were fewer with radial than with femoral access (15·2% vs 17·2%; 0·87, 0·78–0·97; p=0·0128). Compared with heparin, bivalirudin was not associated with fewer major adverse cardiovascular (15·8% vs 16·8%; 0·94, 0·83–1·05; p=0·28) or net adverse clinical events (17·0% vs 18·4%; 0·91, 0·81–1·02; p=0·10). The composite of urgent target vessel revascularisation, stent thrombosis, or net adverse clinical events did not differ with or without post-procedure bivalirudin infusion (17·4% vs 17·4%; 0·99, 0·84–1·16; p=0·90). Interpretation In patients with acute coronary syndrome, radial access was associated with lower rates of net adverse clinical events compared with femoral access, but not major adverse cardiovascular events at 1 year. Bivalirudin with or without post-procedure infusion was not associated with lower rates of major adverse cardiovascular events or net adverse clinical events. Radial access should become the default approach in acute coronary syndrome patients undergoing invasive management. Funding Italian Society of Invasive Cardiology, The Medicines Company, Terumo, amd Canada Research Chairs Programme.

Published
2018

18. FFR prediction model based on conventional quantitative coronary angiography and the amount of myocardium subtended by an intermediate coronary artery stenosis

Author

Carlo D'Agostino, Bruno Trimarco, Luigi Di Serafino, Saverio Lanzone, Maurizio Turturo, Riccardo Savastano, Gabriella Scognamiglio, Giovanni Esposito, DI SERAFINO, Luigi, Scognamiglio, Gabriella, Turturo, Maurizio, Esposito, Giovanni, Savastano, Riccardo, Lanzone, Saverio, Trimarco, Bruno, and D'Agostino, Carlo

Subjects
Coronary angiography, Male, medicine.medical_specialty, Hemodynamics, Coronary stenosis, Fractional flow reserve, 030204 cardiovascular system & hematology, Coronary Angiography, FFR, Severity of Illness Index, 03 medical and health sciences, 0302 clinical medicine, Predictive Value of Tests, Internal medicine, medicine, Humans, Jeopardy score, 030212 general & internal medicine, Retrospective Studies, Myocardial Stunning, business.industry, Coronary Stenosis, iFR, Gold standard (test), Middle Aged, medicine.disease, Prognosis, Vessel diameter, Fractional Flow Reserve, Myocardial, Stenosis, medicine.anatomical_structure, Heart Function Tests, Cardiology, Disease Progression, Female, Radiology, Cardiology and Cardiovascular Medicine, business, Artery, Follow-Up Studies
Abstract

Background Coronary angiography has poor predictive value for functionally significant coronary artery stenosis. The Fractional Flow Reserve (FFR) currently represents the gold standard to define the ischemic potential of epicardial stenosis and, recently, the instantaneous wave-free ratio (iFR), has also been introduced as alternative to the FFR, but it still remains an invasive procedure. We aimed this study in order to evaluate the accuracy of the “Angiography-DeriveD hEmoDynamic index” (ADDED index) to predict the FFR as compared with the iFR. Methods and results Consecutive patients with at least one equivocal stenosis in one major coronary artery were enrolled. Both the FFR and iFR were measured. The amount of jeopardized myocardium was evaluated using the Duke Jeopardy Score (DJS). Two-dimensional quantitative coronary angiography (QCA) was used to assess the angiographic features of the coronary stenosis and both the reference vessel diameter (RVD) and minimal lumen diameter (MLD) were calculated. The ADDED index was defined as the ratio between DJS and MLD. We evaluated 100 intermediate coronary artery stenoses in 83 patients. Both FFR and iFR inversely correlated with the ADDED index (respectively, r2 = 0.59, p < 0.001 and r2 = 0.61, p < 0.001). This latter also showed high accuracy in predicting the FFR value (ROC analysis: 0.94[0.90–0.99], p < 0.001) as well as the iFR (0.91[0.86–0.97], p < 0.001, difference: 0.03 SD 0.04, p = 0.52). Conclusions The ADDED index, taking into account both the MLD and DJS, showed high accuracy to predict FFR and it might be used to detect functionally significant coronary artery stenosis.

Published
2016

19. A comparison between radial artery compression devices for patent hemostasis after transradial percutaneous interventions.

Author

Di Serafino L, Turturo M, Larosa C, Scalamogna M, Cirillo P, Vito Alessandro A, Lanzone S, Bartolomucci F, Granata R, Rea FS, Piccolo R, Franzone A, Gargiulo G, Spaccarotella CAM, Stabile E, and Esposito G

Subjects
Humans, Male, Female, Aged, Middle Aged, Arterial Occlusive Diseases prevention & control, Arterial Occlusive Diseases etiology, Arterial Occlusive Diseases diagnosis, Hemostatic Techniques instrumentation, Hemostatic Techniques adverse effects, Incidence, Hemostasis physiology, Italy epidemiology, Treatment Outcome, Equipment Design, Radial Artery, Percutaneous Coronary Intervention methods, Percutaneous Coronary Intervention adverse effects
Abstract

Objectives: Patent hemostasis (PH) is essential for preventing radial artery occlusion (RAO) after trans-radial procedures; however, it remains unclear how it should be obtained. The aim of this multicenter randomized study was to evaluate whether the use of an adjustable device (AD), inflated with a pre-determined amount of air (AoA), was more effective than a non-adjustable device (non-AD) for achieving PH, thereby reducing the incidence of RAO., Methods: We enrolled a total of 480 patients undergoing transradial procedure at 3 Italian institutions. Before the procedure, a modified Reverse Barbeau Test (mRBT) was performed in all patients to evaluate the AoA to be eventually inflated in the AD. After the procedure, patients were randomized into 2 groups: (1) AD Group, using TR-Band (Terumo) inflated with the pre-determined AoA; and 2) non-AD Group, using RadiStop (Abbott). An RBT was performed during compression to demonstrate the achievement of PH, as well as 24 hours later to evaluate the occurrence of RAO., Results: PH was more often obtained in the AD Group compared with the non-AD Group (90% vs 64%, respectively, P less than .001), with no difference in terms of bleedings. RAO occurred more often in the non-AD Group compared with the AD Group (10% vs 3%, respectively, P less than .001). Of note, mRBT was effective at guiding AD inflation and identifying high-risk patients in whom PH was more difficult to obtain., Conclusions: The use of AD, filled with a predetermined AoA, allowed PH significantly more often compared with non-AD, providing a significantly reduced incidence of RAO.

Published
2024
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