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Your search keyword '"Tucci, Joseph M."' showing total 5 results
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5 results on '"Tucci, Joseph M."'

1. A study of regional gut endoderm potency by analysis of Cdx2 null mutant chimaeric mice

Author

Beck, Felix, Chawengsaksophak, Kallayanne, Luckett, Jenni, Giblett, Susan, Tucci, Joseph M., Brown, Jane, Poulsom, Richard, Jeffery, Rosemary, and Wright, Nicholas A.

Subjects
Developmental biology -- Research, Genetic recombination -- Analysis, Intestines -- Genetic aspects, Intestines -- Physiological aspects, Cloning -- Genetic aspects, Epithelium -- Genetic aspects, Epithelium -- Physiological aspects, Y chromosome -- Genetic aspects, Y chromosome -- Physiological aspects, Gene expression -- Physiological aspects, Biological sciences
Abstract

Inactivation of Cdx2 by homologous recombination results in the development of forestomach epithelium at ectopic sites in pericaecal areas of the midgut of heterozygote mice. Local factors subsequently result in the secondary induction of tissues exhibiting an orderly sequence of tissue types between the ectopic forestomach tissue and the surrounding colon. Clonal analysis of this secondarily generated tissue using Y chromosome painting in chimaeric mice indicates that once differentiated to express Cdx2, host colonic epithelium can only form small intestinal-type epithelium, while Cdx2 mutant cells give rise to a succession of gastric-type tissue but never to a small intestine morphology. Our results indicate a difference in potency between forestomach and midgut precursor endodermal cells. Keywords: Cdx2; Homeobox; Intercalation; Gut development

Published
2003

2. FOLLOWING a legend

Author

Tucci, Joseph M.

Subjects
Computer peripherals industry -- Management, Executives -- Management, EMC Corp. (Hopkinton, Massachusetts) -- Management
Abstract

WHEN JOE TUCCI TOOK the CEO chair at data storage powerhouse EMC, he inherited a healthy company with an enviable track record. Under his predecessor, Mike Ruettgers, the $8.87 billion […]

Published
2001

3. EMC: EMC is the Leader in Helping Oracle Customers Redefine IT

Author

Tucci, Joseph M.

Subjects
DBMS software, Computers
Abstract

WITH CLOUD-ENABLED infrastructure EMC helps Oracle customers consolidate databases and standardize IT infrastructure, while maximizing quality of service for Oracle database environments. Through EMC and Oracle integration, IT organizations can [...]

Published
2015

4. Lessons From the Diamond

Author

Tucci, Joseph M.

Abstract

I'M a pretty good baseball player and a really terrible guitarist. What I've learned from baseball has had a great impact on the kind of manager I've become, but it […]

Published
2007

5. Out of School And Unemployed.

Author

Freeland, Richard M. and Tucci, Joseph M.

Subjects
*SCHOOL dropouts, *UNITED States education system, *INTERNAL revenue
Abstract

The No Child Left Behind Act of 2001 holds the promise of transforming the U.S. education, in large measure by providing new resources and holding schools accountable for the success of their students. The U.S. is experiencing an enormous student-dropout crisis. Dropout problems tend to be more severe among men than among women, are greater among African-Americans and Hispanics than among whites and are particularly acute in many of the nation's large central cities. Without work or access to jobs-skills training and employment programs, these young people are statistically more likely to engage in petty crime and gang activity. Dropouts also contribute little to the tax revenues of federal and state governments and receive a flow of cash and in-kind transfers that far outweighs their tax contributions over their lifetimes.

Published
2003

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