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18 results on '"Tsutsumi, Takanobu"'

1. IgG4-related disease in the Japanese population: a genome-wide association study

Author

Kanno, Atsushi, Okabe, Yoshihiro, Katsushima, Shinji, Inokuma, Tetsuro, Yamashita, Yukitaka, Nakai, Yoshitaka, Nishino, Takayoshi, Kajimura, Kozo, Shibatoge, Mitsushige, Kanda, Naoki, Ido, Akio, Ohana, Masaya, Moriyama, Ichiro, Tatsuta, Hiroshi, Matsumura, Kazuyoshi, Fujikawa, Keita, Gotoh, Norimoto, Tsutsumi, Takanobu, Shimizu, Masakazu, Setoh, Kazuya, Takahashi, Meiko, Tabara, Yasuharu, Mimura, Jun, Nakamura, Takefumi, Kimura, Toshiyuki, Kawanami, Chiharu, Terao, Chikashi, Ota, Masao, Iwasaki, Takeshi, Shiokawa, Masahiro, Kawaguchi, Shuji, Kuriyama, Katsutoshi, Kawaguchi, Takahisa, Kodama, Yuzo, Yamaguchi, Izumi, Uchida, Kazushige, Higasa, Koichiro, Yamamoto, Motohisa, Kubota, Kensuke, Yazumi, Shujiro, Hirano, Kenji, Masaki, Yasufumi, Maguchi, Hiroyuki, Origuchi, Tomoki, Matsui, Shoko, Nakazawa, Takahiro, Shiomi, Hideyuki, Kamisawa, Terumi, Hasebe, Osamu, Iwasaki, Eisuke, Inui, Kazuo, Tanaka, Yoshiya, Ohshima, Koh-ichi, Akamizu, Takashi, Nakamura, Shigeo, Nakamura, Seiji, Saeki, Takako, Umehara, Hisanori, Shimosegawa, Tooru, Mizuno, Nobumasa, Kawano, Mitsuhiro, Azumi, Atsushi, Takahashi, Hiroki, Mimori, Tsuneyo, Kamatani, Yoichiro, Okazaki, Kazuichi, Chiba, Tsutomu, Kawa, Shigeyuki, and Matsuda, Fumihiko

Published
2019
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3. Exome Sequencing Landscape Analysis in Ovarian Clear Cell Carcinoma Shed Light on Key Chromosomal Regions and Mutation Gene Networks

Author

Murakami, Ryusuke, Matsumura, Noriomi, Brown, J.B., Higasa, Koichiro, Tsutsumi, Takanobu, Kamada, Mayumi, Abou-Taleb, Hisham, Hosoe, Yuko, Kitamura, Sachiko, Yamaguchi, Ken, Abiko, Kaoru, Hamanishi, Junzo, Baba, Tsukasa, Koshiyama, Masafumi, Okuno, Yasushi, Yamada, Ryo, Matsuda, Fumihiko, Konishi, Ikuo, and Mandai, Masaki

Published
2017
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4. Sleep disordered breathing and haemoglobin A1c levels within or over normal range and ageing or sex differences: the Nagahama study

Author

Matsumoto, Takeshi, primary, Murase, Kimihiko, additional, Tabara, Yasuharu, additional, Minami, Takuma, additional, Kanai, Osamu, additional, Takeyama, Hirofumi, additional, Sunadome, Hironobu, additional, Nagasaki, Tadao, additional, Takahashi, Naomi, additional, Nakatsuka, Yoshinari, additional, Hamada, Satoshi, additional, Handa, Tomohiro, additional, Tanizawa, Kiminobu, additional, Nakamoto, Isuzu, additional, Wakamura, Tomoko, additional, Komenami, Naoko, additional, Setoh, Kazuya, additional, Kawaguchi, Takahisa, additional, Tsutsumi, Takanobu, additional, Morita, Satoshi, additional, Takahashi, Yoshimitsu, additional, Nakayama, Takeo, additional, Sato, Susumu, additional, Hirai, Toyohiro, additional, Matsuda, Fumihiko, additional, and Chin, Kazuo, additional

Published
2022
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5. Sleep disordered breathing and haemoglobin A1c levels within or over normal range and ageing or sex differences: the Nagahama study.

Author

Matsumoto, Takeshi, Murase, Kimihiko, Tabara, Yasuharu, Minami, Takuma, Kanai, Osamu, Takeyama, Hirofumi, Sunadome, Hironobu, Nagasaki, Tadao, Takahashi, Naomi, Nakatsuka, Yoshinari, Hamada, Satoshi, Handa, Tomohiro, Tanizawa, Kiminobu, Nakamoto, Isuzu, Wakamura, Tomoko, Komenami, Naoko, Setoh, Kazuya, Kawaguchi, Takahisa, Tsutsumi, Takanobu, and Morita, Satoshi

Subjects
AGE differences, SLEEP disorders, SLEEP apnea syndromes, SLEEP duration, PULSE oximeters, SLEEP interruptions, AGE
Abstract

Summary: Recently an association between blood glucose dysregulation and sleep disruption was suggested. The association between sleep disordered breathing, most of which is due to obstructive sleep apnea (OSA) in the general population, and diabetic severity, as well as the impact of antidiabetic treatment, remains unclear. This study aimed to investigate these associations as well as age and sex differences. This cross‐sectional study evaluated 7,680 community participants as the main cohort (population‐based cohort). OSA was assessed by the 3% oxygen desaturation index from pulse oximetry, which was corrected for sleep duration obtained by wrist actigraphy. For arguing the limitations for using pulse oximetry, 597 hospitalised patients, who were assessed by the apnea–hypopnea index from attended polysomnography, were also evaluated as the validation cohort (hospital‐based cohort). Moderate‐to‐severe OSA was more prevalent as haemoglobin A1c (HbA1c) levels increased (<5.6%/5.6%–<6.5%/6.5%–<7.5%/≥7.5%, respectively) in both cohorts (p < 0.001), but only in those without antidiabetic treatment. The HbA1c level was an independent factor for moderate‐to‐severe OSA (population‐based cohort, odds ratio [OR] 1.26, 95% confidence interval [CI] 1.10–1.45; hospital‐based cohort, OR 1.69, 95% CI 1.22–2.33, per 1% increase). These associations were more prominent in the middle‐aged (aged <60 years) than in the elderly (aged ≥60 years) and in women than in men in both cohorts. The prevalence of moderate‐to‐severe OSA in patients with antidiabetic treatment in the hospital‐based cohort was ≥75% regardless of HbA1c levels. In conclusion, an association between the prevalence of OSA and HbA1c level even within or over the normal range was found only in patients without antidiabetic treatment and was more prominent in the middle‐aged and in women. [ABSTRACT FROM AUTHOR]

Published
2023
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6. Association of Sleep-disordered Breathing and Blood Pressure with Albuminuria: The Nagahama Study

Author

Murase, Kimihiko, primary, Matsumoto, Takeshi, additional, Tabara, Yasuharu, additional, Ohler, Adrienne, additional, Gozal, David, additional, Minami, Takuma, additional, Kanai, Osamu, additional, Takeyama, Hirofumi, additional, Takahashi, Naomi, additional, Hamada, Satoshi, additional, Tanizawa, Kiminobu, additional, Wakamura, Tomoko, additional, Komenami, Naoko, additional, Setoh, Kazuya, additional, Kawaguchi, Takahisa, additional, Tsutsumi, Takanobu, additional, Morita, Satoshi, additional, Takahashi, Yoshimitsu, additional, Nakayama, Takeo, additional, Yanagita, Motoko, additional, Hirai, Toyohiro, additional, Matsuda, Fumihiko, additional, and Chin, Kazuo, additional

Published
2022
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7. Sleep disordered breathing and metabolic comorbidities across gender and menopausal status in East Asians; the Nagahama Study

Author

Matsumoto, Takeshi, Murase, Kimihiko, Tabara, Yasuharu, Minami, Takuma, Kanai, Osamu, Takeyama, Hirofumi, Takahashi, Naomi, Hamada, Satoshi, Tanizawa, Kiminobu, Wakamura, Tomoko, Komenami, Naoko, Setoh, Kazuya, Kawaguchi, Takahisa, Tsutsumi, Takanobu, Morita, Satoshi, Takahashi, Yoshimitsu, Nakayama, Takeo, Hirai, Toyohiro, Matsuda, Fumihiko, and Chin, Kazuo

Subjects
obesity, hypertension, diabetes, Sleep disordered breathing, sex difference, mental disorders, dyslipidemia, menopause, cardiovascular diseases, general population, metabolic syndrome, nervous system diseases, respiratory tract diseases
Abstract

It is well known that the prevalence of sleep disordered breathing (SDB) is increased in patients with obesity or metabolic comorbidities. However, the way in which the prevalence of SDB increases in relation to comorbidities according to the severity of obesity remains unclear. This cross-sectional study evaluated 7713 community participants with nocturnal oximetry ≥2 nights. SDB was assessed by the 3% oxygen desaturation index corrected for sleep duration obtained by wrist actigraphy (Acti-ODI3%). SDB severity was defined by Acti-ODI3%. Obesity was defined as body mass index ≥25 kg·/m−2. The prevalence of SDB was 41.0% (95% CI 39.9–42.1), 46.9% (45.8–48.0), 10.1% (9.5–10.8), and 2.0% (1.7–2.3) in normal, mild, moderate, and severe SDB, respectively, with notable sex differences evident (men >post-menopausal women >pre-menopausal women). Comorbidities such as hypertension, diabetes, and metabolic syndrome were independently associated with the prevalence of moderate-to-severe SDB, and coincidence of any one of these with obesity was associated with a higher probability of moderate-to-severe SDB (OR 8.2, 95% CI 6.6–10.2; 7.8, 5.6–10.9; 6.7, 5.2–8.6, respectively). Dyslipidemia in addition to obesity was not additively associated with the prevalence of moderate to-severe SDB. The number of antihypertensive drugs was associated with SDB (p for trend, 生活習慣病に睡眠時無呼吸症候群がひそむことを解明 --アジア最大資料数のながはまコホートより--. 京都大学プレスリリース. 2020-05-19.

Published
2020

8. Changes in the difference between subjective and objective sleep duration according to sleep duration or sleep disordered breathing: The Nagahama Study

Author

Takahashi, Naomi, primary, Matsumoto, Takeshi, additional, Nakatsuka, Yoshinari, additional, Murase, Kimihiko, additional, Tabara, Yasuharu, additional, Takeyama, Hirofumi, additional, Minami, Takuma, additional, Hamada, Satoshi, additional, Kanai, Osamu, additional, Tanizawa, Kiminobu, additional, Nakamoto, Isuzu, additional, Kawaguchi, Takahisa, additional, Setoh, Kazuya, additional, Tsutsumi, Takanobu, additional, Takahashi, Yoshimitsu, additional, Handa, Tomohiro, additional, Wakamura, Tomoko, additional, Komenami, Naoko, additional, Hirai, Toyohiro, additional, Matsuda, Fumihiko, additional, Nakayama, Takeo, additional, and Chin, Kazuo, additional

Published
2020
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9. Sleep disordered breathing and metabolic comorbidities across sex and menopausal status in East Asians: the Nagahama Study

Author

Matsumoto, Takeshi, primary, Murase, Kimihiko, additional, Tabara, Yasuharu, additional, Minami, Takuma, additional, Kanai, Osamu, additional, Takeyama, Hirofumi, additional, Takahashi, Naomi, additional, Hamada, Satoshi, additional, Tanizawa, Kiminobu, additional, Wakamura, Tomoko, additional, Komenami, Naoko, additional, Setoh, Kazuya, additional, Kawaguchi, Takahisa, additional, Tsutsumi, Takanobu, additional, Morita, Satoshi, additional, Takahashi, Yoshimitsu, additional, Nakayama, Takeo, additional, Hirai, Toyohiro, additional, Matsuda, Fumihiko, additional, and Chin, Kazuo, additional

Published
2020
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10. IgG4-related disease in the Japanese population: a genome-wide association study

Author

Terao, Chikashi, primary, Ota, Masao, additional, Iwasaki, Takeshi, additional, Shiokawa, Masahiro, additional, Kawaguchi, Shuji, additional, Kuriyama, Katsutoshi, additional, Kawaguchi, Takahisa, additional, Kodama, Yuzo, additional, Yamaguchi, Izumi, additional, Uchida, Kazushige, additional, Higasa, Koichiro, additional, Yamamoto, Motohisa, additional, Kubota, Kensuke, additional, Yazumi, Shujiro, additional, Hirano, Kenji, additional, Masaki, Yasufumi, additional, Maguchi, Hiroyuki, additional, Origuchi, Tomoki, additional, Matsui, Shoko, additional, Nakazawa, Takahiro, additional, Shiomi, Hideyuki, additional, Kamisawa, Terumi, additional, Hasebe, Osamu, additional, Iwasaki, Eisuke, additional, Inui, Kazuo, additional, Tanaka, Yoshiya, additional, Ohshima, Koh-ichi, additional, Akamizu, Takashi, additional, Nakamura, Shigeo, additional, Nakamura, Seiji, additional, Saeki, Takako, additional, Umehara, Hisanori, additional, Shimosegawa, Tooru, additional, Mizuno, Nobumasa, additional, Kawano, Mitsuhiro, additional, Azumi, Atsushi, additional, Takahashi, Hiroki, additional, Mimori, Tsuneyo, additional, Kamatani, Yoichiro, additional, Okazaki, Kazuichi, additional, Chiba, Tsutomu, additional, Kawa, Shigeyuki, additional, Matsuda, Fumihiko, additional, Kanno, Atsushi, additional, Okabe, Yoshihiro, additional, Katsushima, Shinji, additional, Inokuma, Tetsuro, additional, Yamashita, Yukitaka, additional, Nakai, Yoshitaka, additional, Nishino, Takayoshi, additional, Kajimura, Kozo, additional, Shibatoge, Mitsushige, additional, Kanda, Naoki, additional, Ido, Akio, additional, Ohana, Masaya, additional, Moriyama, Ichiro, additional, Tatsuta, Hiroshi, additional, Matsumura, Kazuyoshi, additional, Fujikawa, Keita, additional, Gotoh, Norimoto, additional, Tsutsumi, Takanobu, additional, Shimizu, Masakazu, additional, Setoh, Kazuya, additional, Takahashi, Meiko, additional, Tabara, Yasuharu, additional, Mimura, Jun, additional, Nakamura, Takefumi, additional, Kimura, Toshiyuki, additional, and Kawanami, Chiharu, additional

Published
2019
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11. Impact of sleep characteristics and obesity on diabetes and hypertension across genders and menopausal status: the Nagahama study

Author

Matsumoto, Takeshi, primary, Murase, Kimihiko, additional, Tabara, Yasuharu, additional, Gozal, David, additional, Smith, Dale, additional, Minami, Takuma, additional, Tachikawa, Ryo, additional, Tanizawa, Kiminobu, additional, Oga, Toru, additional, Nagashima, Shunsuke, additional, Wakamura, Tomoko, additional, Komenami, Naoko, additional, Setoh, Kazuya, additional, Kawaguchi, Takahisa, additional, Tsutsumi, Takanobu, additional, Takahashi, Yoshimitsu, additional, Nakayama, Takeo, additional, Hirai, Toyohiro, additional, Matsuda, Fumihiko, additional, and Chin, Kazuo, additional

Published
2018
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17. Differences between subjective and objective sleep duration according to actual sleep duration and sleep-disordered breathing: the Nagahama Study.

Author

Takahashi N, Matsumoto T, Nakatsuka Y, Murase K, Tabara Y, Takeyama H, Minami T, Hamada S, Kanai O, Tanizawa K, Nakamoto I, Kawaguchi T, Setoh K, Tsutsumi T, Takahashi Y, Handa T, Wakamura T, Komenami N, Morita S, Hirai T, Matsuda F, Nakayama T, and Chin K

Subjects
Actigraphy, Cross-Sectional Studies, Female, Humans, Male, Oxygen, Sleep, Sleep Apnea Syndromes complications, Sleep Apnea Syndromes epidemiology
Abstract

Study Objectives: Since subjective sleep duration (SSD) is considered to be longer than objective sleep duration (OSD), results of SSD minus OSD (SSD-OSD) might always be thought to be positive. Some recent reports showed different results, but exact results have not been obtained. The difference between SSD and OSD may change according to OSD. We investigated this difference and its association with sleep-disordered breathing (SDB) or nonrestorative sleep., Methods: This cross-sectional study evaluated 6,908 community residents in Nagahama, Japan. SSD was determined by self-administered questionnaire. OSD was measured by wrist actigraphy and sleep diary. SDB was assessed according to the 3% oxygen desaturation index adjusted for OSD., Results: Worthy of notice was that SSD was shorter than OSD for those with SSD longer than 6.98 hours in all participants, 7.36 hours in males, and 6.80 hours in females. However, SSD was longer than OSD (mean ± SD: 6.49 ± 1.07 vs 6.01 ± 0.96; P < .001) overall, as SSD is considered to be longer than OSD. In patients with SDB, the difference between SSD-OSD was greater when OSD was s horter. The difference also depended on SDB severity. The degree of positivity between OSD and SSD was a significant factor in nonrestorative sleep (odds ratio: 2.691; P < .001)., Conclusions: When OSD was slightly less than 7 (6.98) hours, participants reported or perceived SSD > OSD. When OSD was > 6.98 hours, participants reported or perceived SSD < OSD. Patients with SDB reported longer SSD than OSD according to severity of SDB. Evaluating SSD, OSD, and their differences may be useful for managing sleep disturbances, including nonrestorative sleep., Citation: Takahashi N, Matsumoto T, Nakatsuka Y, et al. Differences between subjective and objective sleep duration according to actual sleep duration and sleep-disordered breathing: the Nagahama Study. J Clin Sleep Med . 2022;18(3):851-859., (© 2022 American Academy of Sleep Medicine.)

Published
2022
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18. Impact of sleep-disordered breathing on glucose metabolism among individuals with a family history of diabetes: the Nagahama study.

Author

Minami T, Matsumoto T, Tabara Y, Gozal D, Smith D, Murase K, Tanizawa K, Takahashi N, Nakatsuka Y, Hamada S, Handa T, Takeyama H, Oga T, Nakamoto I, Wakamura T, Komenami N, Setoh K, Tsutsumi T, Kawaguchi T, Kamatani Y, Takahashi Y, Morita S, Nakayama T, Hirai T, Matsuda F, and Chin K

Subjects
Female, Glucose, Humans, Male, Middle Aged, Oximetry, Prevalence, Risk Factors, Diabetes Mellitus, Type 2 complications, Diabetes Mellitus, Type 2 epidemiology, Sleep Apnea Syndromes complications, Sleep Apnea Syndromes epidemiology
Abstract

Study Objectives: It is well known that a family history of diabetes (FHD) is a definitive risk factor for type 2 diabetes. It has not been known whether sleep-disordered breathing (SDB) increases the prevalence of diabetes in those with an FHD., Methods: We assessed SDB severity in 7,477 study participants by oximetry corrected by objective sleep duration determined by wrist actigraphy. Glycated hemoglobin ≥6.5% and/or current medication for diabetes indicated the presence of diabetes. In addition to the overall prevalence, the prevalence of recent-onset diabetes during the nearly 5 years before the SDB measurements were made was investigated., Results: Of the 7,477 participants (mean age: 57.9; range: 34.2-80.7; SD: 12.1 years; 67.7% females), 1,569 had an FHD. The prevalence of diabetes in FHD participants with moderate-to-severe SDB (MS-SDB) was higher than in those without SDB (MS-SDB vs without SDB: all, 29.3% vs 3.3% [P < .001]; females, 32.6% vs 1.9% [P < .001]; males, 26.2% vs 11.7% [P = .037]). However, multivariate analysis showed that MS-SDB was significantly associated with a higher prevalence of diabetes only in FHD-positive females (odds ratio [95% confidence interval]: females, 7.43 [3.16-17.45]; males, 0.92 [0.37-2.31]). Among the FHD-positive participants, the prevalence of recent-onset diabetes was higher in those with MS-SDB than those without SDB, but only in females (MS-SDB vs without SDB: 21.4% vs 1.1%; P < 0.001)., Conclusions: MS-SDB was associated with diabetes risk in females with an FHD, and future studies are needed on whether treatment of SDB in females with an FHD would prevent the onset of diabetes., (© 2021 American Academy of Sleep Medicine.)

Published
2021
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