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25 results on '"Tsutsumi, Ryo"'

4. Autologous Platelet-Rich Plasma Improves Pregnancy Outcomes of Patients with Thin Endometrium Regardless Endometrial Thickening: Multicenter Retrospective Study with Elimination of Embryonic Confounders

Author

Suzuki, Satoshi, primary, Kusumi, Maki, additional, Maeda, Tomoko, additional, Kawai, Kiyotaka, additional, Kawamura, Toshihiro, additional, Okamoto, Eri, additional, Jo, Toushun, additional, Tsutsumi, Ryo, additional, Takamizawa, Satoru, additional, Nakayama, Takahiro, additional, Nabeta, Motowo, additional, Nishiyama, Yukio, additional, Nomiyama, Mari, additional, Furui, Kenji, additional, Morimoto, Yoshiharu, additional, and Tsutsumi, Osamu, additional

Published
2022
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10. Autologous Platelet-Rich Plasma Improves Pregnancy Outcomes of Patients with Thin Endometrium Regardless Endometrial Thickening: Multicenter Retrospective Study with Elimination of Embryonic Confounders

Author

Suzuki, Satoshi, Kusumi, Maki, Maeda, Tomoko, Kawai, Kiyotaka, Kawamura, Toshihiro, Okamoto, Eri, Jo, Toushun, Tsutsumi, Ryo, Takamizawa, Satoru, Nakayama, Takahiro, Nabeta, Motowo, Nishiyama, Yukio, Nomiyama, Mari, Furui, Kenji, Morimoto, Yoshiharu, and Tsutsumi, Osamu

Abstract

Objective:To determine whether endometrial thickening is an important factor for pregnancy outcomes in platelet-rich plasma (PRP) treatment for patients with thin endometrium.Methods:Data from the registry database of the Japan Gynecologic PRP Study Group from April 2019 to October 2021 were analyzed retrospectively. A total of 208 patients who underwent single blastocyst transfer (SBT) after PRP due to thin endometrium (¡8 mm) in their previous cycle were included in the study. Their pregnancy outcomes were compared with their own historical data before PRP infusion. The same patient group was then divided into 136 patients whose endometrium thickened after PRP and 72 patients whose endometrium did not, and the pregnancy outcomes of the two groups were compared. Furthermore, to eliminate embryonic confounding, 28 patients who had single euploid blastocyst transfer (SEBT) with preimplantation genetic testing for aneuploidy (PGT-A) were selected from the same patient group and divided into two groups of 22 patients whose endometrium thickened and 6 patients whose endometrium did not, and the pregnancy outcomes were compared in the same method.Results:After PRP administration, the clinical pregnancy rate, live birth rate, and miscarriage rate were all significantly improved compared with the historical controls (34.1 vs 20.0, P<0.01; 22.6 vs 3.9, P<0.01; 33.8 vs 73.4, P<0.01). There were no statistically significant differences in the respective rates between the “thickened endometrium” group and the “unthickened endometrium” group in SBT group (36.0 vs 30.5%, P=0.43; 25.7 vs 16.7%, P=0.11; 28.5 vs 45.4%, P=0.16, respectively). Likewise, in the SEBT with PGT-A group, there were no statistically significant differences in results between the two groups (36.4 vs 50%, P=0.30; 36.4 vs 50%, P=0.30; 0 vs 0%, respectively).Conclusions:PRP administration to patients with thin endometrium improves pregnancy outcomes even when endometrial thickening is not achieved.

Published
2023
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16. Parasitic Myomas developing after a Laparoscopic Myomectomy: Case Report

Author

Oki, Shinya, primary, Hirata, Tetsuya, additional, Takamura, Masashi, additional, Kojima, Machiko, additional, Sanada, Yuko, additional, Saitou, Ako, additional, Tsutsumi, Ryo, additional, Harada, Miyuki, additional, Koga, Kaori, additional, Hiraike, Osamu, additional, Osuga, Yutaka, additional, and Fujii, Tomoyuki, additional

Published
2014
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17. The progesterone-responsive gene 14-3-3τ enhances the transcriptional activity of progesterone receptor in uterine cells

Author

Ito, Masanori, primary, Urano, Tomohiko, additional, Hiroi, Hisahiko, additional, Momoeda, Mikio, additional, Saito, Mayuko, additional, Hosokawa, Yumi, additional, Tsutsumi, Ryo, additional, Zenri, Fumiko, additional, Koizumi, Minako, additional, Nakae, Hanako, additional, Horie-Inoue, Kuniko, additional, Fujii, Tomoyuki, additional, Yano, Tetsu, additional, Kozuma, Shiro, additional, Inoue, Satoshi, additional, and Taketani, Yuji, additional

Published
2012
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23. Increased risk of placenta previa is associated with endometriosis and tubal factor infertility in assisted reproductive technology pregnancy.

Author

Takemura, Yuri, Osuga, Yutaka, Fujimoto, Akihisa, Oi, Nagisa, Tsutsumi, Ryo, Koizumi, Minako, Yano, Tetsu, and Taketani, Yuji

Subjects
HUMAN reproductive technology research, PLACENTA praevia, ENDOMETRIOSIS, FEMALE reproductive organ diseases, CESAREAN section, MATERNAL age, LOGISTIC regression analysis
Abstract

Although assisted reproductive technology (ART) is suspected to increase the risk of placenta previa, a life-threatening complication of pregnancy, the reason is poorly understood. We recruited consecutive 318 pregnancies conceived by ART in our clinic and examined relation of ten variables, i.e. maternal age, gravidity, parity, male or female fetus, previous abortion, previous cesarean delivery, endometriosis, ovulatory disorder, tubal disease, and male infertility, to placenta previa, by logistic regression analysis. As a result, we found that endometriosis (odds ratio = 15.1; 95% CI = 7.6-500.0) and tubal disease (odds ratio = 4.4; 95% CI = 1.1-26.3) were significantly associated with placenta previa. It would be preferable to take the increased risk of placenta previa into account in treating ART pregnancy with endometriosis and tubal disease. [ABSTRACT FROM AUTHOR]

Published
2013
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24. Successful pregnancy following low-dose hCG administration in addition to hMG in a patient with hypothalamic amenorrhea due to weight loss.

Author

Tsutsumi, Ryo, Fujimoto, Akihisa, Osuga, Yutaka, Harada, Miyuki, Takemura, Yuri, Koizumi, Minako, Yano, Tetsu, and Taketani, Yuji

Subjects
*OVULATION, *AMENORRHEA, *HYPOTHALAMIC hormones, *INTRACYTOPLASMIC sperm injection, *GONADOTROPIN, *LUTEINIZING hormone
Abstract

We describe successful ovulation induction with low-dose hCG administration in addition to hMG in a patient with refractory hypothalamic amenorrhea. A 24-year-old woman with weight loss-related amenorrhea underwent ovulation induction and intracytoplasmic sperm injection (ICSI). Administration of exogenous gonadotropins was ineffective in ovulation induction. Supplementation with low-dose hCG in order to increase luteinizing hormone (LH) activity in the late follicular phase produced late folliculogenesis and steroidogenesis, and ovulation was then successfully induced. This report reacknowledges the critical role that LH plays cooperatively with follicle-stimulating hormone in both folliculogenesis and steroidogenesis. [ABSTRACT FROM AUTHOR]

Published
2012
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