106 results on '"Tsur N"'
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2. Posttraumatic orientation to bodily signals: The engraving of trauma in bodily perceptions
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Tsur, N., primary and Solomon, Z., additional
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- 2023
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3. Intergenerational transmission of childhood maltreatment and eating disorder behaviors: Shedding light on the mother-daughter dyad and grandmother-mother-daughter triad
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Talmon, A., primary and Tsur, N., additional
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- 2023
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4. Significance of tibial MRI findings of special forces recruits at the onset of their training
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Milgrom, Charles, Tsur, N, Eshed, I, Milgrom, Y, Beyth, S, Spitzer, E, Gofman, I, and Finestone, A S
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IntroductionMRI is commonly used to evaluate medial tibial stress syndrome (MTSS), based on grading assessments developed in civilian populations. When MTSS represents stress fracture, rest is required to allow for bone remodelling to occur. False positive evaluations can lead to unnecessary recruit attrition.MethodsThirty randomly selected new recruits to a special forces training unit underwent MRI of their tibias using the T2-Dixon sequence at the onset of training. Evaluation was according to the Fredericson MTSS grading system. Prior to undergoing MRI, anthropomorphic measurements, a survey of sports history and an orthopaedic examination of subject tibias were performed. Orthopaedic follow-up was through 11 weeks of training.ResultsMedial periosteal oedema without the presence of bone marrow oedema, corresponding to a grade 1 stress reaction, was present on MRI in 10 recruits (17 tibias). In only one case did the periosteal oedema include the posterior aspect of the medial cortex where medial tibial stress fractures usually occur. Tibial tenderness was present in seven tibias on examination done just prior to the MRI studies, but none were symptomatic and only one had periosteal oedema present on MRI, but without anatomical correlation between the site of the tenderness and the periosteal oedema. During subsequent training, five tibias in four recruits developed pain and tenderness. Two had periosteal oedema in their prior MRIs, but the location did not coincide anatomically with that of the tibial tenderness. The time from stopping sports before induction and the presence of periosteal oedema was not significant.ConclusionPeriosteal oedema, one of the hallmarks used in MRI grading systems to evaluate MTSS, was found to have a 37.7% false positive rate for anatomically corresponding tibial tenderness at the time of the examination and during subsequent training, indicating the grading systems’ low utility for the military.
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- 2024
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5. Significance of tibial MRI findings of special forces recruits at the onset of their training
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Milgrom, Charles, primary, Tsur, N, additional, Eshed, I, additional, Milgrom, Y, additional, Beyth, S, additional, Spitzer, E, additional, Gofman, I, additional, and Finestone, A S, additional
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- 2022
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6. Composition and morphology changes in olive fruit as indication of maturation
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Avidan, B., Meni, Y., and Tsur, N.
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- 2007
7. Response of patients with melanoma to immune checkpoint blockade – insights gleaned from analysis of a new mathematical mechanistic model
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Tsur, N., primary, Kogan, Y., additional, Rehm, M., additional, and Agur, Z., additional
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- 2020
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8. Pain and Anxiety: The Difference between Monitoring and Sensitivity to Bodily Signals
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Ginzburg, K., primary, Tsur, N., additional, Barak-Nahum, A., additional, and Defrin, R., additional
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- 2014
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9. The Saint Bartholomew's Day Massacre and Baroque Tendencies in France: The Impact of Religious Turmoils on the Aesthetics of the French Renaissance
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Kuperty-Tsur, N., primary
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- 2007
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10. Pain and Anxiety: The Difference between Monitoring and Sensitivity to Bodily Signals.
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Ginzburg, K., Tsur, N., Barak-Nahum, A., and Defrin, R.
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- 2014
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11. Intergenerational Transmission of Posttraumatic Orientation to Bodily Signals Following Child Maltreatment.
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Talmon A and Tsur N
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Recent studies have indicated that CM (child maltreatment) may influence individuals' perception of their bodies, often resulting in a posttraumatic orientation to bodily signals (OBS). Given the intricate relationship between bodily and interpersonal experiences, it is hypothesized that posttraumatic OBS may be intergenerationally transmitted. However, knowledge regarding this phenomenon, and its underlying mechanisms, remains limited. Two studies tested (a) the link between CM and posttraumatic OBS, mediated by posttraumatic stress (PTS) symptoms and attachment security, and (b) the intergenerational transmission of a posttraumatic OBS following CM among dyads of parents and their young adult offspring. The first study included 445 young adults (mean age = 352, SD = 10.2), and the second study included 393 dyads (parents' mean age = 58, SD = 5.91; offspring's mean age = 27, SD = 3.91). The participants completed self-reported questionnaires. Study 1 found that posttraumatic OBS was associated with CM, through the mediation of PTS symptoms (indirect effect = 0.15, p = .005), and insecure attachment (indirect effects between 0.132 and 1.44, p < .006). The second study found two pathways of intergenerational transmission. The first pathway showed indirect paths between parents' CM exposure and offspring's posttraumatic OBS, through parents' reaction to CM (PTS symptoms, anxious attachment, and avoidant attachment) and posttraumatic OBS (indirect effects between 0.006 and 0.013, p < .039). The second pathway revealed indirect links between parents' CM exposure and offspring's posttraumatic OBS, through parents' and offspring's reaction to CM (indirect effects between 0.006 and 0.56, p < .015). The study's findings add empirical evidence that posttraumatic OBS is a significant implication of CM. The second study illuminates the intergenerational transmission of a posttraumatic OBS following parental CM exposure, uncovering PTS symptoms, and insecure attachment styles as potential underlying mechanisms., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interests with respect to the authorship and/or publication of this article.
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- 2024
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12. "No one wants you back, you will stay here forever": Exploring the story of the Israeli children who were held in captivity by Hamas.
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Katz C, Jacobson M, Friedman-Hauser G, Aviad M, Levin I, and Tsur N
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- Humans, Israel, Child, Male, Female, Adolescent, Qualitative Research, Interviews as Topic, Armed Conflicts psychology
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Background: Recent armed conflicts around the world have highlighted that child abduction and hostage-taking are pervasive, and of high concern for child rights, child development, and well-being. Little research exists on child hostages in specific conflict contexts., Objective: This study was designed to examine child hostage stories conveyed by the Israeli children who were released from captivity in Gaza, post the October 7, 2023, Hamas-led attack on Israel. Child hostage stories, as published in Israeli media, were based on recorded interviews with the children., Participants and Setting: Fifty-seven child interviews were identified, based on 18 children and youth who were aged 8 to 18. The child interviews in the media were in Hebrew., Methods: Child interviews were gathered from popular Israeli news channels, which were manually searched using systematic keywords. A search was also conducted through Google and YouTube. All of the included recorded interviews with the released child hostages were analyzed qualitatively, using inductive thematic analysis., Results: Three main themes were generated: 1) the event of being kidnapped from Israel, with three sub-themes, including the kidnapping experience, atrocities witnessed, and entering the territory of Gaza; 2) the story of captivity, with four sub-themes including experiencing harsh environmental conditions, emotional abuse, medical neglect, physical and sexual abuse; and 3) the release from captivity, including experiencing the release, being put into a media show, separating from other hostages, experiencing fear during the exiting, and experiencing disbelief about their freedom., Conclusions: The Israeli children held captive by Hamas in 2023 endured horrific experiences. Researching these children's experiences through their own words is essential for validating their stories, bearing witness, and deepening our current understanding of the trauma and the violation of these children's rights. This study acknowledges the limitations in its methodology, while also demonstrating the viability of collecting children's testimonies from the media when done ethically. This research advocates for future studies to examine children held captive in such contexts around the globe, and urges the implementation of children's rights paradigm and trauma-informed policy and practice in supporting these children., Competing Interests: Declaration of competing interest None., (Copyright © 2024 Elsevier Ltd. All rights reserved.)
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- 2024
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13. Gender-Related Aspects of Laryngeal Squamous Cell Carcinoma: A Retrospective Cohort Study.
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Tsur N, Zloczower E, Tunik M, Amir I, Yosefof E, Havakuk HS, Hamzany Y, and Kurman N
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- Humans, Male, Female, Retrospective Studies, Middle Aged, Aged, Sex Factors, Survival Rate, Neoplasm Staging, Adult, Disease-Free Survival, Laryngeal Neoplasms mortality, Laryngeal Neoplasms pathology, Laryngeal Neoplasms therapy, Carcinoma, Squamous Cell pathology, Carcinoma, Squamous Cell mortality, Carcinoma, Squamous Cell therapy
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Objectives: Laryngeal squamous cell carcinoma (SCC) is a predominantly male illness. Although the rate of female patients increased, a knowledge gap exists in the medical literature regarding gender-based differences., Design: Retrospective cohort study., Setting: Adult patients treated for laryngeal SCC in a tertiary medical centre between 2006 and 2020. Data were collected on demographics, clinical presentation, treatment modalities, disease recurrence and survival status., Participants: Two hundred ninety-one patients with laryngeal SCC, 50 (17.2%) females and 241 (82.8%) males., Main Outcome Measures: Disease-specific survival (DSS), overall survival (OS) and disease-free survival (DFS), as well as differences in disease characteristics and treatment modalities., Results: Tumour subsites differed significantly between females and males (36% vs. 19.5% supraglottic, 62% vs. 80.5% glottic and 2% vs. 0% subglottic, respectively; p = 0.006). Females were diagnosed at younger ages (61.7 ± 10.58 vs. 65.87 ± 11.11 years, p = 0.016) and advanced-stage disease (58% vs. 39.4%, p = 0.018). Females were treated with combined modalities at higher rates (36% vs. 54.8% for single modality, p = 0.031). DSS rates did not differ between genders (log-rank p = 0.12). Despite being diagnosed at more advanced disease stages, females demonstrated prolonged median OS compared to males (130.17 vs. 106.17 months, log-rank p = 0.017). No significant differences in DFS were observed (log-rank p = 0.32). In a multivariate Cox proportional hazards model, male gender remained an independent negative OS predictor (HR = 2.08; CI, 1.10-3.96; p = 0.025), along with increasing age (HR = 1.06; CI, 1.04-1.09; p < 0.001) and advanced disease stage (HR = 1.7; CI, 1.08-2.67; p = 0.023)., Conclusions: Our findings suggest the importance of considering gender-specific factors in the management of laryngeal SCC., (© 2024 The Author(s). Clinical Otolaryngology published by John Wiley & Sons Ltd.)
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- 2024
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14. Association between the number of individuals injured in a traumatic event and posttraumatic stress disorder among hospitalized trauma patients.
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Talmy T, Bulis S, Radomislensky I, Bushinsky S, Tsur N, Gelman D, Paulman O, Gendler S, Tsur AM, Almog O, and Benov A
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Posttraumatic stress disorder (PTSD) often occurs following mass casualty events, yet the connection between the number of individuals injured in an event and PTSD risk in smaller-scale events (i.e., involving one or several injured persons) remains unclear. We conducted a registries-based study cross-referencing three databases across the continuum of care for military trauma patients hospitalized for traumatic injuries. The study population was categorized into three groups based on the number of injured individuals involved (i.e., single injured person, two to four [2-4] injured people, and five or more [≥ 5] injured people), and PTSD prevalence was assessed using long-term disability claim diagnoses. Overall, 4,030 military personnel were included (age at injury: Mdn = 20 years), and 18.3% were subsequently diagnosed with PTSD, with the highest prevalence in events involving ≥ 5 injured individuals (35.8%). Regression analyses adjusted for potential confounders revealed that being injured in an event with 2-4 injured persons, OR = 1.68, 95% CI [1.31, 2.15], or ≥ 5 injured persons, OR = 2.36, 95% CI [1.79, 3.13], was associated with increased odds of developing PTSD compared to being the sole injured person. The findings suggest a direct association between the number of injured individuals in an event and PTSD prevalence among traumatic injury survivors. The results underscore the importance of early diagnosis and interventions to prevent PTSD in individuals injured in multicasualty and mass casualty events., (© 2024 The Author(s). Journal of Traumatic Stress published by Wiley Periodicals LLC on behalf of International Society for Traumatic Stress Studies.)
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- 2024
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15. A Nationwide, Population-Based Study of Intelligence and Hearing Loss among 3,104,670 Adolescents.
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Tsur N, Reuven Y, Rittblat M, Abuhasira S, Lubarski A, Hilly O, and Beer Z
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Purpose: Epidemiological studies have demonstrated a relationship between general intelligence (GI) in youth and hearing loss (HL). However, no large-scale study assessed the relations of GI in late adolescence with conductive HL (CHL) and sensorineural HL (SNHL), stratified by severity. This study examined the connection between HL and GI in late adolescence., Methods: Cross-sectional study on mandatory premilitary recruitment data recorded during 1967-2019 of patients aged 17-19. We compared GI between SNHL, CHL, and those with normal hearing. In addition, we used logistic regression to measure the associations between HL and GI after adjuring for age, sex, education, and socioeconomic status., Results: Among 3,104,851 adolescents assessed, 20,075 (0.6%) exhibited HL. We categorized GI into three levels for analysis: low (lowest category), medium, and high (reference category). Adjusted odds ratios (ORs) revealed that SNHL was associated with lower GI levels, with ORs ranging from 1.3 (95% confidence interval [CI] 1.4-1.2) for the lowest GI category to 1.1 (95% CI 1.15-0.04) for the medium category. CHL (CHL) also demonstrated significant associations, with ORs from 1.8 (95% CI 1.9-1.6) for the lowest GI level to 1.1 (95% CI 1.2-0.9) for medium. Further analysis revealed a statistically significant, severity-dependent relationship between SNHL and the odds of being in the lowest GI quartile (Q1). Specifically, the ORs for SNHL ranged from 1.2 (95% CI 1.1-1.3) to 1.3 (95% CI 1.1-1.5) as severity increased, indicating a strong link between greater SNHL severity and reduced cognitive performance. In contrast, CHL did not show a consistent correlation between its severity and GI outcomes, with an OR of 1.6 (95% CI 1.2-2.3) across severity levels., Conclusion: We report a strong relationship between HL and GI in late adolescence. SNHL, but not CHL, demonstrated a severity-based decline in GI. The results highlight the value of early, specifically targeted therapies for HL that consider its etiology and degree., (© 2024 The Author(s). Published by S. Karger AG, Basel.)
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- 2024
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16. When to choose intraosseous access in prehospital trauma care: A registry-based study from the Israel Defense Forces.
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Rittblat M, Tsur N, Karas A, Gendler S, Beer Z, Radomislensky I, Almog O, Tsur AM, Avital G, and Talmy T
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Purpose: Prompt vascular access is crucial for resuscitating bleeding trauma casualties in prehospital settings but achieving peripheral intravenous (PIV) access can be challenging during hemorrhagic shock due to peripheral vessel collapse. Early intraosseous (IO) device use is suggested as an alternative. This study examines injury characteristics and factors linked to IO access requirements., Methods: A registry-based cohort study from the Israel Defense Forces Trauma Registry (2010 - 2023) included trauma casualties receiving PIV or IO access prehospital. Casualties who had at least one documented PIV or IO access attempt were included, while those without vascular access were excluded. Casualties requiring both PIV and IO were classified in the IO group. Univariable logistic regression assessed the factors associated with IO access. Results were reported as odds ratios (OR) with 95% confidence intervals (CI), and significant difference was set at p < 0.05., Results: Of 3462 casualties (86.3% male, the median age: 22 years), 3287 (94.9%) received PIV access and 175 (5.1%) had IO access attempts. In the IO group, 30.3% received freeze-dried plasma and 23.4% received low titer group O whole blood, significantly higher than that in the PIV group. Prehospital mortality was 35.0% in the IO group. Univariable analysis showed significant associations with IO access for increased PIV attempts (OR = 1.69; 95% CI: 1.34 - 2.13) and signs of profound shock (OR = 11.0; 95% CI: 5.5 - 23.3)., Conclusion: Profound shock signs are strongly linked to the need for IO access in prehospital settings with each successive PIV attempt increasing the likelihood of requiring IO conversion. IO access often accompanies low titer group O whole blood or freeze-dried plasma administration and higher prehospital mortality, indicating its use in emergent resuscitation situations. Early IO consideration is advised for trauma casualties with profound shock., Competing Interests: Declaration of competing interest There are no conflicts of interest to declare., (Copyright © 2024 Chinese Medical Association. Published by Elsevier B.V. All rights reserved.)
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- 2024
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17. Utilizing the glucose challenge test during pregnancy as a predictor of future diabetes risk.
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Frankel M, Tsur N, Pollack R, and Tsur A
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- Humans, Female, Pregnancy, Adult, Retrospective Studies, Israel epidemiology, Young Adult, Blood Glucose analysis, Risk Factors, Adolescent, Middle Aged, Risk Assessment methods, Diabetes, Gestational diagnosis, Diabetes, Gestational blood, Diabetes, Gestational epidemiology, Glucose Tolerance Test, Predictive Value of Tests
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Background: Gestational Diabetes Mellitus (GDM) presents a significant health concern during pregnancy, predisposing individuals to future diabetes. Despite established postpartum diabetes screening guidelines, adherence to follow-up remains inadequate., Aims: This study aimed to assess the predictive value of the 50-gram glucose challenge test (GCT) for post-pregnancy diabetes development., Materials and Methods: A population-based retrospective cohort study was conducted on pregnant women aged 18-45 who underwent GCT screening between November 2007 and July 2017 in a large Israeli community medical organization. Baseline characteristics, GCT results, and diabetes development during follow-up were analyzed using univariate and multivariate Cox regression analyses., Results: Among 8,675 women included, 2.4% developed diabetes over a median follow-up of 73.23 months. Elevated GCT results correlated with a higher risk of future diabetes, with a 4% rise in risk per 1 mg/dL increase in glucose above 140 mg/dL. Multivariate analysis revealed a 60-fold rise in the risk of future diabetes in women with GCT results ≥ 200 mg/dL compared to those with GCT < 140 mg/dL, adjusting for age, body mass index, pre-pregnancy glucose, cholesterol, and triglycerides. A GCT result between 140 and 199 mg/dL was a predictor of future diabetes, even when adjusted for GDM based on a subsequent GTT if performed., Conclusions: GCT results during pregnancy strongly predict future diabetes development, with higher GCT values significantly increasing risk. Recognizing abnormal GCT results as indicative of a prediabetic state offers a practical approach for risk stratification, facilitating early diagnosis, and intervention in post-pregnancy care., (© 2024. The Author(s).)
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- 2024
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18. Factors associated with failure of intraosseous access in prehospital trauma treatment by military medical personnel.
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Rittblat M, Kotovich D, Tsur N, Beer Z, Radomislensky I, Gendler S, Almog O, Tsur AM, Avital G, and Talmy T
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Introduction: Intraosseous devices have become an alternative to peripheral intravenous (PIV) access. Despite the established success of intraosseous devices in laboratory and simulator studies, there is a lack of data regarding their real-world utilisation in prehospital settings. Therefore, this study aims to evaluate the success rates of intraosseous access in a prehospital military context and identify factors associated with failure., Methods: Using the Israel Defense Forces (IDF) Trauma Registry, we retrospectively collected data from 2010 to 2023. The primary outcome was the first pass success rate of intraosseous access, and logistic regression models were applied to identify variables associated with first pass failure., Results: The study included 172 trauma patients who underwent attempted intraosseous access with 46.5% cases which were classified as military events. The median age was 22 years, and 17.3% were paediatric patients. First pass success was achieved in 67.4% of cases, with a cumulative success rate of 80.8% after multiple attempts. Moreover, significant differences were noted when examining the success rate of the three intraosseous devices used by the IDF teams, with the highest success rate being documented for the NIO Adult versus the EZ-IO or the BIG (81.4%; 76.7%; 62.4%). However, logistic regression analysis revealed that the number of PIV access attempts was the only variable significantly associated with decreased odds of achieving first pass intraosseous access., Conclusion: These findings suggest that intraosseous devices are a viable alternative for establishing vascular access in prehospital military settings. However, success rates were slightly lower than previous reports, potentially due to the severity of injuries in the study cohort. Our analyses revealed a higher number of PIV access attempts correlated with reduced first pass intraosseous success, possibly stemming from caregiver proficiency in obtaining vascular access. Further research is needed to explore additional factors affecting intraosseous access success rates., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2024. No commercial re-use. See rights and permissions. Published by BMJ.)
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- 2024
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19. Intergenerational associations between childhood maltreatment, post-traumatic stress symptoms, and chronic pain in young adult offspring and their parents.
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Talmon A, Shilo G, and Tsur N
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- Humans, Female, Male, Adult, Middle Aged, Young Adult, Adult Children psychology, Intergenerational Relations, Surveys and Questionnaires, Chronic Pain psychology, Chronic Pain epidemiology, Stress Disorders, Post-Traumatic epidemiology, Stress Disorders, Post-Traumatic psychology, Parents psychology, Adult Survivors of Child Abuse psychology, Adult Survivors of Child Abuse statistics & numerical data
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Findings have revealed a strong link between exposure to child maltreatment (CM) and later chronic pain. Concurrently, other findings have been grounded in the understanding that CM consequences may not end with the exposed individual, rather, they extend to their offspring. However, little is known regarding the possible intergenerational transmission of chronic pain following CM. This study examines whether chronic pain among parents and their young adult offspring may be associated with parental exposure to CM. Three hundred ninety-three parent-offspring dyads (parents' mean age = 58, SD = 5.91 years; offspring's mean age = 27, SD = 3.91 years) completed self-report questionnaires, assessing CM (CTQ), posttraumatic stress (PTS) and disturbances in self-organisation (DSO) symptoms (ITQ), and chronic pain. CM was associated with chronic pain mediated by DSO symptoms among parents (indirect effect = 0.77; p = 0.007) and PTS symptoms among offspring (indirect effect = 0.285; p = 0.005). Offspring chronic pain was significantly associated with parental CM through two intergenerational paths: the mediation of parents' DSO symptoms and chronic pain (indirect effect = 0.298; p = 0.011), and through parents' PTS symptoms and offspring's PTS symptoms (indirect effect = 0.077; p = 0.004). This study's findings support the relevance of the intergenerational transmission of chronic pain following parental exposure to CM. Furthermore, the findings reveal complex PTS symptoms as a possible underlying mechanism for the intergenerational associations of chronic pain following CM., (© 2024 John Wiley & Sons Ltd.)
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- 2024
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20. Perioperative and postoperative management of tympanostomy tube insertion: a survey of otorhinolaryngologists in Israel.
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Dudkiewicz D, Bismuth EM, Tsur N, Gilony D, and Hod R
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Background: Tympanostomy tube insertion is a standard surgical procedure in children to address middle ear infections and effusion-related hearing and speech development issues. Perioperative treatments like ear drops containing antibiotics, steroids, and tube irrigation with saline aim to prevent complications, yet no universal gold standard treatment exists. Despite guidelines, practice preferences among ENT specialists vary, motivating this study to investigate perioperative management practices in Israel., Method: A survey was distributed among ENT surgeons, collecting data on their main workplace, sub-specialty, preoperative hearing test requirements, tube irrigation practices, tube selection criteria, and timing of tube removal. Distribution and association with main workplaces were examined., Results: The survey achieved a response rate of 27.33%. Most participants routinely required preoperative hearing tests, with a preference for conducting them within three months prior to surgery (62.2%). Tube irrigation during the procedure was less common among surgeons in the public system (p = 0.007). In response to the COVID-19 pandemic, the majority of respondents maintained their established practices (96.3%), while a small proportion (3.7%) adapted by replacing two in-person meetings with one virtual session. Variations in tube removal timing based on the main workplace were noted, with private practitioners opting for earlier removal (p = 0.002) and were less permissive in water deprivation practices (p = 0.053)., Conclusion: This study provides insights into the practices and preferences of ENT surgeons in tympanostomy tube insertion procedures in Israel. Adherence to standardized practices was observed, with variations influenced by the primary workplace. Despite the COVID-19 pandemic, minimal changes were made to established practices. Further research and consensus are necessary to optimize patient outcomes and develop tailored guidelines in this field., (© 2024. The Author(s).)
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- 2024
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21. Corrigendum to "Long-term outcomes of cricothyroidotomy versus endotracheal intubation in military personnel: A retrospective comparative analysis cohort study" Volume 300, August 2024, Pages 416-424/YJSRE18737.
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Tsur N, Talmy T, Rittblat M, Radomislensky I, Meizosod JP, Almog O, and Gendler S
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- 2024
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22. Subacute Thyroiditis Following COVID-19 and COVID-19 Vaccination.
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Duskin-Bitan H, Robenshtok E, Peretz A, Beckenstein T, Tsur N, Netzer D, Cohen AD, Saliba W, Shimon I, and Gorshtein A
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- Humans, Female, Male, Middle Aged, Adult, Aged, Vaccination statistics & numerical data, Case-Control Studies, SARS-CoV-2, Thyroiditis, Subacute epidemiology, Thyroiditis, Subacute etiology, COVID-19 prevention & control, COVID-19 epidemiology, COVID-19 complications, COVID-19 Vaccines adverse effects
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Objective: COVID-19 infection and immunizations have been implicated in developing a range of thyroid diseases, including subacute thyroiditis (SAT). This study aimed to evaluate the association between COVID-19 infection and/or COVID-19 vaccination with SAT., Methods: A population of 3 million adults insured by Clalit Health Services was evaluated from March 2020 to September 2022. Patients with a new diagnosis of SAT were identified and matched in a 1:10 ratio to a control group. Each control was assigned an index date that was identical to that of their matched case, defined as the date of SAT diagnosis. Multivariate conditional logistic regression models were used to evaluate the association between COVID-19 infection, vaccine, and thyroiditis., Results: A total of 3221 patients with SAT were matched with 32 210 controls. Rates of COVID-19 vaccination (first, second, or third dose) and COVID-19 infection were evaluated prior to the date of SAT diagnosis (disease group) or index date (control group) to detect a possible association. No difference was detected between the groups in relation to vaccinations at the 30 days, 60 days, and 90 days of time points (P = .880/0.335/0.174, respectively). No difference was found between groups in relation to COVID-19 infection at these time points (P = .735/0.362/0.956, respectively). There was higher use of medications for the treatment of thyroiditis, including nonsteroidal anti-inflammatory drugs (28.6% vs 7.9%, P < .01), steroids (10.3% vs 1.8%, P < .01), and beta-blockers (18.3% vs 5.4%, P < .01)., Conclusion: Based on this large population study, no association was found between COVID-19 infection and/or the COVID-19 vaccine and SAT., Competing Interests: Disclosure The authors have no conflicts of interest to disclose., (Copyright © 2024 AACE. Published by Elsevier Inc. All rights reserved.)
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- 2024
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23. Long-Term Outcomes of Cricothyroidotomy Versus Endotracheal Intubation in Military Personnel: A Retrospective Comparative Analysis Cohort Study.
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Tsur N, Talmy T, Rittblat M, Radomislensky I, Almog O, and Gendler S
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- Humans, Retrospective Studies, Male, Adult, Female, Israel epidemiology, Airway Management methods, Airway Management statistics & numerical data, Treatment Outcome, Young Adult, Thyroid Cartilage surgery, Emergency Medical Services statistics & numerical data, Registries statistics & numerical data, Middle Aged, Follow-Up Studies, Intubation, Intratracheal statistics & numerical data, Intubation, Intratracheal adverse effects, Intubation, Intratracheal methods, Military Personnel statistics & numerical data, Cricoid Cartilage surgery
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Introduction: Emergency airway management is critical in trauma care. Cricothyroidotomy (CRIC) is a salvage procedure commonly used in failed endotracheal intubation (ETI) or difficult airway cases. However, more data is needed regarding the short and long-term complications associated with CRIC. This study aimed to evaluate the Israel Defense Forces experience with CRIC over the past 2 decades and compare the short-term and long-term sequelae of prehospital CRIC and ETI., Methods: Data on patients undergoing either CRIC or ETI in the prehospital setting between 1997 and 2021 were extracted from the Israel Defense Forces trauma registry. Patient data was then cross-referenced with the Israel national trauma registry, documenting in-hospital care, and the Israel Ministry of Defense rehabilitation department registry, containing long-term disability files of military personnel., Results: Of the 122 patients with short-term follow-up through initial hospitalization, 81% underwent prehospital ETI, while 19% underwent CRIC. There was a higher prevalence of military-related and explosion injuries among the CRIC patients (96% versus 65%, P = 0.02). Patients who underwent CRIC more frequently exhibited oxygen saturations below 90% (52% versus 29%, P = 0.002). Injury Severity Score was comparable between groups.No significant difference was found in intensive care unit length of stay and need for tracheostomy. Regarding long-term complications, with a median follow-up time of 15 y, CRIC patients had more upper airway impairment, with most suffering from hoarseness alone. One patient in the CRIC group suffered from esophageal stricture., Conclusions: This retrospective comparative analysis did not reveal significant short or long-term sequelae among military personnel who underwent prehospital CRIC. The long-term follow-up did not indicate severe aerodigestive impairments, thus suggesting that this technique is safe. Along with the high success rates attributed to this procedure, we recommend that CRIC remains in the armamentarium of trauma care providers. The findings of this study could provide valuable insights into managing difficult airway in trauma care and inform clinical decision-making in emergency settings., (Copyright © 2024 Elsevier Inc. All rights reserved.)
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- 2024
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24. [A 3-YEAR COMPARATIVE COHORT - TRENDS IN OTOLARYNGOLOGY CONSULTATIONS IN THE PEDIATRIC EMERGENCY DEPARTMENT DURING THE COVID-19 PANDEMIC].
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Tsur N, Frig O, Eyal Y, Kohlberg G, Hod R, Zloczower E, and Reuven Y
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- Humans, Child, Retrospective Studies, Female, Child, Preschool, Male, Adolescent, Infant, Otorhinolaryngologic Diseases therapy, Otorhinolaryngologic Diseases epidemiology, SARS-CoV-2, Israel epidemiology, Hospitals, Pediatric statistics & numerical data, Pandemics, COVID-19 epidemiology, Emergency Service, Hospital statistics & numerical data, Referral and Consultation statistics & numerical data, Otolaryngology trends, Otolaryngology statistics & numerical data, Otolaryngology methods, Otolaryngology organization & administration
- Abstract
Aims: The SARS-CoV-2 (COVID-19) pandemic has changed emergency department (ED) referral trends worldwide., Objectives: We aim to investigate inpatient consultation in the ED of a pediatric otolaryngology-head and neck surgery service during the COVID-19 pandemic compared to two preceding years., Methods: A retrospective chart review of children under 18 years who had an otolaryngology consultation in Schneider Children's Hospital ED from 2018-2020., Results: Of the 4,213 patients who underwent otolaryngology consultations in the ED, infection pathogenesis was the leading cause, presenting in 51.1% of the patients during the three-year study period. During the year 2020, the proportion of patients admitted to the ED who were referred to otolaryngology-head and neck consultations was significantly higher than in previous years (p<0.001), especially during the summer (p=0.001). In addition, increased rates were observed of trauma, foreign body pathogenesis, and mastoiditis (16% vs. 13%, p=0.03; 13% vs. 8%, p<0.001; and 2.4% vs. 0.9%, p = 0.01, respectively)., Conclusions: During the COVID-19 pandemic, otolaryngology consultations in the emergency department increased substantially. Improvements in community clinics service may alleviate this increased burden.
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- 2024
25. Peritraumatic Pain in Child Maltreatment: A Systematic Literature Review.
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Tsur N, Talmon A, and Shemesh N
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- Humans, Child, Chronic Pain psychology, Chronic Pain etiology, Stress Disorders, Post-Traumatic psychology, Female, Male, Child Abuse psychology
- Abstract
Extensive research has been conducted on the link between trauma, child maltreatment (CM), and chronic pain. Although the risk of suffering from chronic pain among CM survivors has been established, much less is known about the experience of pain during CM incidents or whether such peritraumatic pain sensations are associated with later chronic pain. This scoping review was conducted to synthesize the existing literature on pain during and a short time following CM (i.e., peritraumatic pain). Utilizing the preferred reporting items for systematic reviews and meta-analyses guidelines, the current review included 11 manuscripts, which met the following criteria: (a) refer to physical pain experienced during or a short time after CM, (b) were published in peer-reviewed journals, and (c) were written in English. The review demonstrated that most of the included studies were not intentionally focused on peritraumatic pain, the majority used qualitative research methods, and all were cross-sectional. Furthermore, although validated questionnaires are available, most of the studies did not utilize such measures. Those that intentionally reported pain demonstrated its high intensity and prevalence in CM incidents, indicating that pain is inherently embedded in the experience of maltreatment. The findings spotlight an underdeveloped research realm on a phenomenon that may hold significant empirical, clinical, and legal implications. Research endeavors should initiate interdisciplinary bodies of knowledge to establish well-validated research methodologies that properly quantify peritraumatic pain in trauma and CM., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
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- 2024
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26. Intelligence among ear deformities and cleft lip and/or alveolus and/or cleft palate patients during 50 years in Israel.
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Tsur N, Beer Z, Rittblat M, Yaacobi D, Elmograbi A, and Reuven Y
- Subjects
- Humans, Cross-Sectional Studies, Female, Male, Adolescent, Israel epidemiology, Hearing Loss epidemiology, Child, Cleft Palate epidemiology, Cleft Lip epidemiology, Intelligence
- Abstract
Purpose: We evaluated hearing loss and general intelligence among persons with auricle anomalies and cleft lip and/or alveolus and/or cleft palate (CLAP)., Methods: A nationwide cross-sectional study of data recorded during 1966-2019, as mandatory pre-military recruitment of individuals., Results: Of 3 182 892 adolescents, 548 were diagnosed with auricle anomalies and 2072 with CLAP. For the latter, the adjusted odds ratios for the low, low to medium and medium general intelligence categories compared to the highest category were 1.4 [95% CI 1.5-1.2], 1.2 [95% CI 1.4-1.1] and 1.1 [95% CI 1.2-0.9] respectively. The corresponding values for the auricle anomalies were not significant., Conclusions: General intelligence was impaired among individuals with CLAP, but no significant correlation was found among individuals suffering from auricle anomalies., (© 2023 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)
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- 2024
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27. Opioids and Cancer: Current Understanding and Clinical Considerations.
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Sah D, Shoffel-Havakuk H, Tsur N, Uhelski ML, Gottumukkala V, and Cata JP
- Subjects
- Humans, Pain Management methods, Quality of Life, Analgesics, Opioid therapeutic use, Analgesics, Opioid adverse effects, Neoplasms drug therapy, Cancer Pain drug therapy
- Abstract
Pain is one of the most common symptoms in patients with cancer. Pain not only negatively affects the quality of life of patients with cancer, but it has also been associated with reduced survival. Pain management is therefore a critical component of cancer care. Prescription opioids remain the first-line approach for the management of moderate-to-severe pain associated with cancer. However, there has been increasing interest in understanding whether these analgesics could impact cancer progression. Furthermore, epidemiological data link a possible association between prescription opioid usage and cancer development. Until more robust evidence is available, patients with cancer with moderate-to-severe pain may receive opioids to decrease suffering. However, future studies should be conducted to evaluate the role of opioids and opioid receptors in specific cancers.
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- 2024
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28. The Transition of Resident Surgeons to Special Forces Resident Surgeons During Wartime - Preparedness Above all.
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Tsur N, Rittblat M, and Wiesel O
- Abstract
Competing Interests: The authors declare that they have no conflict of interest
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- 2024
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29. Prognostic Significance of Regional Disease in Young Patients with Oral Cancer: A Comparative Study.
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Yosefof E, Tsur N, Zavdy O, Kurman N, Dudkiewicz D, Yehuda M, Bachar G, Shpitzer T, Mizrachi A, and Tzelnick S
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- Humans, Male, Middle Aged, Aged, Aged, 80 and over, Adult, Female, Prognosis, Retrospective Studies, Disease-Free Survival, Neoplasm Staging, Carcinoma, Squamous Cell pathology, Mouth Neoplasms pathology
- Abstract
Background: Regional metastases are considered the most important prognostic factor in OSCC patients. We aimed to investigate the impact of regional disease among different age groups with OSCC., Methods: A retrospective comparison between patients 40 years old or younger, 41-69 years old, and 70 years or older treated for OSCC between 2000 and 2020 in a tertiary-care center., Results: 279 patients were included. The mean age was 65 ± 17.7 and 133 were male (47.7%). Thirty-six (12.9%) were 40 years old or younger, 101 (36.2%) were 41-69 years and 142 (50.9%) were 70 years or older. Five-year overall survival and disease-specific survival (DSS) were significantly better among patients younger than 40 compared to the mid-age group and patients 70 years or older (76.7% vs. 69.4% vs.48.2%, Log-rank p < 0.001, and 76.7% vs. 75.3% vs. 46.5%, Log-rank p < 0.001, respectively). While an association between regional spread and overall survival and DSS was demonstrated among all age groups, the odds ratio (OR) for death of any cause and death of disease regarding cervical metastasis was much higher among patients younger than 40 compared with the 41-69 and 70+ age groups (death of any cause-OR = 23, p-value = 0.008, OR = 2.6, p-value = 0.026, OR = 2.4, p-value = 0.13, respectively. Death of disease-OR = 23, p-value = 0.008, OR = 2.3, p-value = 0.082, OR = 4.1, p-value = 0.001, respectively). In univariate analysis, regional metastasis was associated with disease-free survival only among patients younger than 40 (p-value = 0.04)., Conclusions: Regional metastases correspond with worse prognosis in young patients compared to older patients. These patients may benefit from a comprehensive treatment approach with close post-treatment follow-up., Level of Evidence: 3 Laryngoscope, 134:2212-2220, 2024., (© 2023 The Authors. The Laryngoscope published by Wiley Periodicals LLC on behalf of The American Laryngological, Rhinological and Otological Society, Inc.)
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- 2024
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30. Gestational diabetes and risk of future diabetes in a multi-ethnic population.
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Tsur N, Frankel M, Cahn A, and Tsur A
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- Pregnancy, Female, Humans, Ethnicity, Retrospective Studies, Glucose Tolerance Test, Risk Factors, Diabetes, Gestational epidemiology
- Abstract
Aim: To investigate ethnic disparities in risk of gestational diabetes-mellitus (GDM) and future diabetes., Methods: A population-based retrospective cohort study of women who underwent a 100-g oral glucose-tolerance-test (oGTT) during pregnancy between 2007 and 2017 in Clalit-Health-Services of the Jerusalem district. Univariate and multivariate logistic regression analyses were used to compare the risk of GDM in Arab versus Jewish women. Further, Cox-regression analysis was used to establish the risk of future diabetes., Results: A total of 9875 women, 71 % of Jewish ethnicity and 29 % of Arab ethnicity were included. Arab women had a higher incidence of GDM compared to Jewish women (17.3 % vs. 10.6 %, p < 0.001), which persisted after adjusting for age, BMI, and metabolic profile (aOR 1.7; CI 1.48-2.0, P < 0.001). Additionally, Arab ethnicity was associated with an increased risk of future diabetes, even after adjusting for GDM status (aHR 5.9; 95 % CI 3.7-9.4, P < 0.001)., Conclusions: Women of Arab ethnicity have a higher risk for both GDM and future diabetes, a risk that is beyond the initial increased risk associated with GDM. These findings highlight the need for increased focus on preventing diabetes in women of Arab ethnicity, especially those with a history of GDM., Competing Interests: Declaration of competing interest The authors have no relevant financial or non-financial interests to disclose. The authors have no conflicts of interest to declare that are relevant to the content of this article., (Copyright © 2024. Published by Elsevier Inc.)
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- 2024
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31. Hearing Impairment and Severe Attention Deficit/Hyperactivity Disorder: A Nationwide Study.
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Tsur N, Zloof Y, Rittblat M, Reuven Y, Simchoni M, Derazne E, Yitzchaki Z, Adler L, Shlaifer A, Manuva O, and Beer Z
- Subjects
- Male, Adolescent, Humans, Female, Cross-Sectional Studies, Social Class, Attention Deficit Disorder with Hyperactivity complications, Attention Deficit Disorder with Hyperactivity epidemiology, Attention Deficit Disorder with Hyperactivity diagnosis, Disabled Persons, Hearing Loss complications, Hearing Loss epidemiology
- Abstract
Background: The association between hearing impairment and attention-deficit/hyperactivity disorder (ADHD) is unclear. Therefore, we aimed to assess this association in Israel's national sample of over 1.1 million adolescents., Methods: We conducted a nationwide, population-based, cross-sectional study of all Israeli adolescents (n = 1,175,534, 58% males; mean age, 17 yrs) who were examined before mandatory military service during 2004 to 2020. Board-certified specialists confirmed diagnoses of hearing impairment and severe ADHD., Main Outcomes and Measures: We compared the prevalence of severe ADHD in adolescents with and without hearing impairment. Associations were analyzed using logistic regression models and sensitivity analyses accounting for hearing impairment type (sensorineural vs. conductive) and severity., Results: Of the 8,769 adolescents with hearing impairment, 57 were diagnosed with severe ADHD (prevalence = 0.65%). Of the 1,166,765 adolescents without hearing impairment, 3,936 were diagnosed with severe ADHD (prevalence = 0.29%). We found a significant association between hearing impairment and severe ADHD (odds ratio = 1.93 [95% confidence interval, 1.47-2.49]), which persisted in a multivariable model adjusted to age, sex, socioeconomic status, educational status, cognitive performance, and immigration status (odds ratio = 1.70 [95% confidence interval, 1.29-2.20]). The association also persisted when stratified by hearing impairment type (sensorineural vs. conductive) and severity., Conclusions: Adolescents with hearing impairment had 70% increased odds of severe ADHD. Study findings suggest that active screening of patients with hearing impairment for ADHD should be considered., Competing Interests: Conflict of interest disclosures: The authors have no conflicts of interest relevant to this article to disclose., (Copyright © 2024, Otology & Neurotology, Inc.)
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- 2024
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32. Future diabetes risk can be predicted by the number of abnormal oral glucose tolerance test values during pregnancy.
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Tsur N, Pollack R, Frankel M, and Tsur A
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- Female, Pregnancy, Humans, Glucose Tolerance Test, Retrospective Studies, Blood Glucose metabolism, Glucose, Glucose Intolerance complications, Glucose Intolerance diagnosis, Glucose Intolerance epidemiology, Diabetes Mellitus, Type 2 complications, Diabetes Mellitus, Type 2 diagnosis, Diabetes Mellitus, Type 2 epidemiology, Diabetes, Gestational diagnosis, Diabetes, Gestational epidemiology
- Abstract
Aim: To quantify the future risk of type 2 diabetes (T2D) in women with gestational diabetes (GD) based on baseline metabolic characteristics and the number of abnormal values during a 3-hour 100-g oral glucose tolerance test (OGTT)., Materials and Methods: We conducted a population-based retrospective cohort study of 10 023 pregnant women who underwent testing for GD in a large health maintenance organization in Israel using a 100-g OGTT. Glucose values were obtained at four time points, 0, 60, 120 and 180 minutes., Results: We identified 9939 women who met the study criteria. Median follow-up was 3.25 (interquartile range 1.5-5.1; maximum 10.1) years. Using women without GD as reference, women with GD were at an increased risk of future T2D (hazard ratio [HR] 5.33 [95% confidence interval {CI} 3.86-7.34]). This risk increased with a greater number of abnormal OGTT values, with the highest risk seen in women with four abnormal values (HR 16.67 [95% CI 7.94-35.01]). In a multivariate model, a higher number of abnormal values, Arab ethnicity, higher body mass index, triglycerides and prepregnancy glucose were significantly associated with increased risk. Future T2D risk was also affected by the type of OGTT abnormality; an abnormal fasting value had the greatest risk, whereas an abnormal 3-hour value had the lowest risk (HR 3.61 [95% CI 2.42-5.38] vs. 1.50 [95% CI 0.93-2.43], respectively)., Conclusions: GD is a heterogenous disease, with varying degrees of glucose intolerance and subsequent T2D risk. Targeting interventions to women at the highest risk may help to improve postpartum adherence and effective long-term follow-up strategies., (© 2023 The Authors. Diabetes, Obesity and Metabolism published by John Wiley & Sons Ltd.)
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- 2024
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33. Foregoing elective neck dissection for elderly patients with oral cavity squamous cell carcinoma.
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Tsur N, Yosefof E, Dudkiewicz D, Edri N, Stern S, Shpitzer T, Mizrachi A, and Najjar E
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- Humans, Aged, Neck Dissection methods, Squamous Cell Carcinoma of Head and Neck surgery, Retrospective Studies, Neoplasm Staging, Mouth Neoplasms surgery, Mouth Neoplasms pathology, Carcinoma, Squamous Cell pathology, Head and Neck Neoplasms surgery
- Abstract
Objective: Elective neck dissection (END) improves outcomes among clinically node-negative patients with oral cavity squamous cell carcinoma (OCSCC). However, END is of questionable value, considering the potentially higher comorbidities and operative risks in elderly patients., Methods: A retrospective review of all patients older than 65 years of age who were treated for OCSCC at a tertiary care centre between 2005 and 2020 was conducted., Results: Fifty-three patients underwent primary tumour resection alone, and 71 had simultaneous END. Most primary tumours were located on the mobile tongue. The patients who did not undergo END had a higher mean age (81.2 vs. 75.1 years, P < 0.00001), significantly shorter surgeries, and shorter hospitalizations. Occult cervical metastases were found in 24% of the patients who underwent END. The two groups showed no significant differences in overall survival or recurrence rates. Similar results were shown in a subpopulation analysis of patients older than 75 years., Conclusion: Foregoing END in elderly patients with no clinical evidence of neck metastases did not result in lower survival rates or higher recurrence rates., (© 2023 Royal Australasian College of Surgeons.)
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- 2024
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34. Extended cervical approach for retrosternal multinodular goiter.
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Tsur N, Levi L, Frig O, Koch N, Eshel Y, Bachar G, Shpitzer T, Yehuda M, Pescovitz Y, Wiesel O, Dudkiewicz D, and Mizrachi A
- Subjects
- Humans, Male, Retrospective Studies, Thyroidectomy adverse effects, Sternotomy, Postoperative Complications etiology, Goiter, Substernal surgery, Goiter, Substernal etiology, Goiter etiology, Goiter surgery
- Abstract
Objective: Partial or total sternotomy is required for 10% of retrosternal goiter. This study reviewed our experience with an extended cervicotomic approach as an alternative surgical solution for retrosternal goiter., Methods: A retrospective study was performed on patients who underwent partial or total thyroidectomy for retrosternal goiter between 2014 and 2019 at a tertiary medical centre. Data on clinical, radiologic, and pathologic factors were analysed. Peri- and postoperative outcomes were compared between extended and standard cervical approaches to predict the need for an extended cervical approach., Results: The cohort included 265 patients, of whom 245 (92.4%) were treated by standard thyroidectomy. In 17 (6.4%), the standard approach proved insufficient, and the horizontal incision was extended to a T-shape to improve access. The remaining 3 patients required a sternotomy. Use of the extended cervical approach was significantly associated with clinical features such as male gender, diabetes, high body mass index and postoperative hypocalcaemia., Conclusions: The extended cervicotomic approach is an alternative surgical solution for retrosternal goiter, with no increased risk of significant post-operative complications., (Copyright © 2024 Società Italiana di Otorinolaringoiatria e Chirurgia Cervico-Facciale, Rome, Italy.)
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- 2024
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35. Significance of tibial MRI findings of special forces recruits at the onset of their training.
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Milgrom C, Tsur N, Eshed I, Milgrom Y, Beyth S, Spitzer E, Gofman I, and Finestone AS
- Subjects
- Humans, Magnetic Resonance Imaging methods, Edema diagnostic imaging, Tibia diagnostic imaging, Military Personnel
- Abstract
Introduction: MRI is commonly used to evaluate medial tibial stress syndrome (MTSS), based on grading assessments developed in civilian populations. When MTSS represents stress fracture, rest is required to allow for bone remodelling to occur. False positive evaluations can lead to unnecessary recruit attrition., Methods: Thirty randomly selected new recruits to a special forces training unit underwent MRI of their tibias using the T2-Dixon sequence at the onset of training. Evaluation was according to the Fredericson MTSS grading system. Prior to undergoing MRI, anthropomorphic measurements, a survey of sports history and an orthopaedic examination of subject tibias were performed. Orthopaedic follow-up was through 11 weeks of training., Results: Medial periosteal oedema without the presence of bone marrow oedema, corresponding to a grade 1 stress reaction, was present on MRI in 10 recruits (17 tibias). In only one case did the periosteal oedema include the posterior aspect of the medial cortex where medial tibial stress fractures usually occur. Tibial tenderness was present in seven tibias on examination done just prior to the MRI studies, but none were symptomatic and only one had periosteal oedema present on MRI, but without anatomical correlation between the site of the tenderness and the periosteal oedema. During subsequent training, five tibias in four recruits developed pain and tenderness. Two had periosteal oedema in their prior MRIs, but the location did not coincide anatomically with that of the tibial tenderness. The time from stopping sports before induction and the presence of periosteal oedema was not significant., Conclusion: Periosteal oedema, one of the hallmarks used in MRI grading systems to evaluate MTSS, was found to have a 37.7% false positive rate for anatomically corresponding tibial tenderness at the time of the examination and during subsequent training, indicating the grading systems' low utility for the military., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2024. No commercial re-use. See rights and permissions. Published by BMJ.)
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- 2024
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36. Management of first branchial anomalies in children: 20 years of experience.
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Tsur N, Elmograbi A, Levi L, Shpitzer T, Bachar G, Hod R, Sokolov M, and Raveh E
- Subjects
- Child, Humans, Child, Preschool, Retrospective Studies, Postoperative Complications epidemiology
- Abstract
Purpose: Branchial cleft anomalies (BCAs) are common pediatric head and neck lesions; however, only 1-4% involve the first branchial cleft. The rare occurrence of first BCAs, their presentation at a young age, and the possible facial nerve involvement make diagnosis and treatment challenging., Methods: A retrospective chart review was conducted for children diagnosed with their first BCA between 2000 and 2020. Data on demographics, presenting symptoms, physical findings, imaging features, previous surgery, and treatment outcomes were collected and analyzed., Results: The cohort included 17 patients with a median age of 5 years at presentation. Seven (41%) had undergone previous surgical intervention before definitive surgery. Eight were classified as Work Type II anomalies, and nine as Work Type I. Sixteen patients (94%) underwent definitive surgical excision at a median age of 6.9. A parotid approach was used in 10 (62%), with dissection of the mass from the facial nerve, and a retro-auricular or end-aural approach was used in 6 (38%). Complete excision was achieved in 14/16 patients (88%). Three patients had transient facial nerve paresis postoperatively. Recurrence was noted in 3/16 patients (18%). Enhancement in imaging was positively correlated with post-operative complications (R = 0.463, P = 0.018)., Conclusions: First, BCA poses a diagnostic and surgical challenge; thus, definitive surgical treatment is often delayed. The surgical approach should be tailored to the type of anomaly (Work type I or II) and possible facial nerve involvement. Risk factors for post-operative complications are a history of recurrent infections and previous surgical interventions. The presence of contrast enhancement in preoperative imaging should alert surgeons to perioperative challenges and the risk of post-operative complications., (© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
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- 2024
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37. Maltreatment in Daycare Settings: A Review of Empirical Studies in the Field.
- Author
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Talmon A, Ditzer J, Talmon A, and Tsur N
- Subjects
- Humans, Child, Female, Empirical Research, Parents, Family, Child Abuse psychology, Crime Victims psychology
- Abstract
Daycare maltreatment refers to abusive and/or neglectful acts perpetrated by teachers, directors, non-professionals or volunteers, family members of staff, and peers in a daycare setting. Despite growing evidence of its occurrence, the prevalence and consequences of daycare maltreatment for the child, the parent(s), and their dyad are largely unknown. This qualitative systematic literature review was conducted to synthesize the existing literature referring to daycare maltreatment, using Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. In order to be included in the analysis, the manuscripts needed to report empirical findings regarding maltreatment in daycare settings, be written in English, be published in a peer-reviewed journal or a dissertation, and be accessible by our research team. In all, 25 manuscripts met the above criteria and were included in the review. Our results indicate that reports of daycare maltreatment are characterized by early age of abused children, inferring mainly to sexual, physical, and emotional abuse. The majority of these manuscripts reported caregivers' and teachers' abuse, while peer victimization was reported much less. In addition, the findings demonstrated a higher representation of female perpetrators compared to abuse in other scenarios. Although some indications of long-term implications are reported in the manuscripts, a well-validated measure for assessment of daycare maltreatment seems to be lacking. These findings contribute to a more nuanced understanding of the complex experience and ramifications of daycare maltreatment, providing insight into its multi-faceted implications., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
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- 2024
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38. The Long-Term Implications of Rhinitis and Chronic Rhinosinusitis in Young Adults.
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Shopen Y, Tsur N, and Soudry E
- Subjects
- Humans, Young Adult, Adult, Case-Control Studies, Chronic Disease, Rhinitis complications, Rhinitis epidemiology, Rhinitis diagnosis, Sinusitis complications, Sinusitis epidemiology, Sinusitis diagnosis, Asthma complications
- Abstract
Background: The long-term impact of rhinitis and chronic rhinosinusitis (CRS) on general health and medical services utilization in young adults have been limitedly studied., Methods: A case-control study in the Israeli Defense Forces, between the years 2005 and 2019, of all individuals with either rhinitis or CRS and a matched cohort of healthy individuals with a minimum of 5 years of consecutive follow-up., Results: The study groups included 617 patients with rhinitis and 296 patients with CRS and 2739 healthy controls with an average age of 28 years. During a mean follow-up of 8 years, a significant fraction of patients in both study groups were diagnosed with asthma compared to the control group, (26.1% and 23.3% vs. 3.7%, respectively; CI 95%: 12.1%-14.9%, p < 0.0001). 7.6% of patients with rhinitis developed CRS. Significantly increased loss of productivity and medical system utilization were noted in the study groups compared to controls (p < 0.0001). Moreover, deterioration in general health, manifested as loss of physical fitness for combative service was observed in a third of patients during follow-up., Conclusions: Rhinitis and CRS significantly impact productivity and medical service utilization in young adults, as well as general health associated with development of asthma and impairment of physical fitness. A minority of rhinitis patients develop CRS overtime, further affecting this patient group. These patients should be followed up and managed to improve disease control and associated outcomes., Level of Evidence: 3 Laryngoscope, 133:3299-3303, 2023., (© 2023 The American Laryngological, Rhinological and Otological Society, Inc.)
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- 2023
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39. "Many bad things had been happening to me": Children's perceptions and experiences of polyvictimization in the context of child physical abuse.
- Author
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Klebanov B, Tsur N, and Katz C
- Subjects
- Child, Humans, Forensic Medicine, Parents, Social Perception, Physical Abuse, Child Abuse
- Abstract
Background: The association between child maltreatment and polyvictimization has received growing attention since being identified by Finkelhor and colleagues in 2005., Objective: The current study was designed to explore the experiences and perceptions of children who reported polyvictimization during forensic interviews., Methods: This mixed-methods study sample comprised 117 children aged 5-14, referred for the first time to forensic interviews following suspected physical abuse by a parent. More than one-third of the children reported polyvictimization. A thematic analysis was carried out to spotlight these children's experiences., Results: The analysis identified three main themes: the way children comprehend the polyvictimization, the consequences of the polyvictimization regarding the children's negative self-attribution, and the way the polyvictimization was constructed through the dynamic with the forensic interviewers., Conclusions: The findings pointed to the importance of the forensic interview platform in assessing children's maltreatment burden. The current study also provided a glance into the possible involvement of the mechanics of self-blame among maltreated children. These findings have the potential to enhance our understanding of the excessive psychological toll taken on polyvictimized children., (Copyright © 2023 Elsevier Ltd. All rights reserved.)
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- 2023
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40. Post-radiotherapy osteomyelitis of the cervical spine in head and neck cancer patients.
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Tsur N, Segal E, Kurman N, Tzelnick S, Wiesel O, Wilk L, Hamzany Y, Bachar G, and Shoffel-Havakuk H
- Abstract
Objective: To evaluate patient characteristics, risk factors, disease course, and management of cervical vertebral osteomyelitis in patients who had radiation for head and neck cancers., Methods: A retrospective cohort study (case series) of patients diagnosed with post-radiation osteomyelitis of the cervical spine between 2012 and 2021. Data were collected from the patient's medical files., Results: Seven patients (71% male) with post-radiation cervical osteomyelitis were reviewed. The median patient age was 64 years. The mean interval between diagnosis of osteomyelitis and the first and last radiotherapy course was 8.3 and 4.0 years, respectively. A medical or surgical event preceded the diagnosis in four patients (57%) by a mean of 46.25 days. Common imaging findings were free air within the cervical structures and fluid collection. Four patients recovered from osteomyelitis during the follow-up within an average of 65 days., Conclusion: Post-radiation osteomyelitis is characterized by a subtle presentation, challenging diagnosis, prolonged treatment, and poor outcome. Clinicians should maintain a high index of suspicion for the long-term after radiotherapy. Multidisciplinary evaluation and management are warranted., Advances in Knowledge: The study describes post-radiotherapy osteomyelitis of the cervical spine, a rare and devastating complication. Literature data regarding this complication are sparse., (© 2023 The Authors. Published by the British Institute of Radiology.)
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- 2023
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41. Implications for future humanitarian aid missions: Lessons from point-of injury and hospital care for Syrian refugees.
- Author
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Talmy T, Cohen-Manheim I, Radomislensky I, Gelikas S, Tsur N, Benov A, Koler T, Glassberg E, Almog O, and Gendler S
- Subjects
- Male, Humans, Young Adult, Adult, Adolescent, Female, Retrospective Studies, Syria epidemiology, Hospitals, Refugees, Relief Work
- Abstract
Background: Warzone humanitarian medical aid missions are infrequent and applying lessons from these missions is vital to ensuring preparedness for future crises. Between 2013-2018, the Israel Defense Forces Medical Corps (IDF-MC) provided humanitarian medical aid to individuals injured in the Syrian Civil War who chose to seek medical assistance at the Israeli-Syrian border. Patients requiring care surgical or advanced care were transferred to civilian medical centers within Israel. This study aims to describe the injury characteristics and management of hospitalized Syrian Civil War trauma patients over a five-year period., Methods: Retrospective cohort analysis cross-referencing data from the IDF trauma registry, documenting prehospital care, and the Israel National Trauma Registry, documenting in-hospital care, between 2013 and 2018. Syrian trauma patients hospitalized in Israeli hospitals were cross-referenced between the two registries. Multivariable logistic regression was applied to identify independent factors associated with in-hospital mortality., Results: Overall, 856 hospitalized trauma patients were included following definitive cross-matching. The median age was 23 years, and 93.3% were males. Blast (n = 532; 62.1%) and gunshot (n = 241; 28.2%) were the most common injury mechanisms. Injury Severity Score was ≥25 for 28.8% of patients and most common body regions with severe injury (Abbreviated Injury Scale≥3) were the head (30.7%) and thorax (25.0%). Intensive care unit admission was required for 40.1% of patients, and the median hospital stay was 13 days. In-hospital mortality was recorded for 73 (8.5%). Signs of shock upon emergency department admission and severe head injury were significantly associated with mortality in the adjusted model whereas age of <18 years was associated with decreased odds for in-hospital mortality., Conclusions: Trauma patients hospitalized in Israel following injuries sustained in the Syrian Civil War were characterized by a high prevalence of blast injuries with concomitant involvement of several body regions. Future missions should ensure preparedness for complex multi-trauma, often involving the head, and ensure high intensive care and surgical capacities., Competing Interests: Declaration of Competing Interest The authors declare no conflicts of interest. This study was performed as part of the Israel Defense Forces Trauma and Combat Medicine Branch efforts to improve the quality of combat casualty care and received no external funding or support., (Copyright © 2023 Elsevier Ltd. All rights reserved.)
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- 2023
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42. Spinal Backboard-Necessity or Hazard? The IDF Clinical Practice Guidelines and Policy.
- Author
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Eyal Y, Tsur N, Gendler S, Almog O, and Beer Z
- Subjects
- Humans, Practice Guidelines as Topic, Immobilization methods, Immobilization instrumentation, Immobilization standards, Emergency Medical Services methods, Emergency Medical Services standards, Transportation of Patients methods, Transportation of Patients standards, Spinal Cord Injuries therapy
- Abstract
Introduction: Prehospital spinal immobilization using a cervical collar and a backboard has been standard practice for suspected spinal cord injuries (SCIs) since the 1960s. Multiple studies have shown that the disadvantages of the spinal backboard outweigh its advantages. This report aims to present a review of the current literature along with the revised IDF protocol regarding patients with suspected SCI., Methods: In 2019, the IDF Medical Corps (IDFMC) convened a multidisciplinary expert committee to revise the IDFMC protocols regarding the use of spinal backboards. Prior to convening the committee, a review of the pertinent literature was done by conducting a thorough clinical evaluation in "PubMed" and "Google Scholar" databases to identify recent studies investigating traumatic SCI and the prehospital military use of spinal backboards., Results: There were no documented studies that have managed to prove the efficacy of spinal backboards to prevent exacerbation of spinal injuries during mobilization. Despite being a good tool for extraction from vehicles and combat arenas, more than 11 studies have shown that backboards may even result in adverse outcomes such as pain due to the contact between board and skin, the formation of decubitus ulcers, hypothermia, and inadequate ventilation., Conclusion: In light of the evidence showing the potential harmful effects of the routine use of spinal backboards, the IDF guidelines have been revised and now recommends avoiding the routine use of spinal backboards and using a standard stretcher for transporting potential SCI patients. Current IDF guidelines recommend using a backboard for the extraction of an entrapped patient and for obtunded or unconscious patients with obvious deformity or mechanism for spinal trauma., (© The Association of Military Surgeons of the United States 2022. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
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- 2023
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43. The Predictors of Persistent Posttracheostomy Tracheocutaneous Fistula and Successful Surgical Closure.
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Yosefof E, Tsur N, Boldes T, Najjar E, Mizrachi A, Shpitzer T, Hamzany Y, and Bachar G
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- Adult, Humans, Retrospective Studies, Trachea, Tracheostomy adverse effects, Postoperative Complications epidemiology, Postoperative Complications surgery, Postoperative Complications etiology, Cutaneous Fistula etiology, Cutaneous Fistula surgery, Tracheal Diseases etiology, Tracheal Diseases surgery
- Abstract
Objective: Persistent tracheocutaneous fistula is a well-described complication of prolonged tracheostomy, with a prevalence of about 70% when decannulation is performed after more than 16 weeks. Predictors of its occurrence and outcome of treatment in adults remain unclear. The aim of the study was to describe our experience with the treatment of persistent posttracheostomy tracheocutaneous fistula in adults and to investigate factors associated with its formation and with the success of surgical closure., Study Design: Retrospective cohort., Setting: Tertiary medical center., Methods: Patients who underwent open-approach tracheostomy between 2000 and 2020 were identified by database review. Data on background, need for surgical closure, and the surgical outcome was collected from the medical files and analyzed statistically between groups., Results: Of 516 patients identified, 127 with sufficient long-term follow-up data were included in the study. Compared to patients whose fistula closed spontaneously (n = 85), patients who required surgical closure (n = 42) had significantly higher rates of smoking, laryngeal or thyroid malignancy, and airway obstruction as the indication for tracheostomy, on both univariate and multivariate analysis. In a comparison of patients with successful (n = 29) or failed (n = 11) surgical closure, factors significantly associated with failure were prior radiotherapy and lower preoperative albumin level, on univariate analysis., Conclusion: Smoking, thyroid or laryngeal malignancy, and airway obstruction indication are risk factors for persistent posttracheostomy tracheocutaneous fistula. Patients should be closely followed after tracheostomy and referred for surgery if the fistula fails to close. Before surgery, careful evaluation of the patient's nutritional status and consideration of prior radiation treatment is mandatory., (© 2023 The Authors. Otolaryngology-Head and Neck Surgery published by Wiley Periodicals LLC on behalf of American Academy of Otolaryngology-Head and Neck Surgery Foundation.)
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- 2023
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44. The Personification of Chronic Pain: An Examination Using the Ben-Gurion University Illness Personification Scale (BGU-IPS).
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Tsur N, Noyman-Veksler G, Elbaz I, Weisman L, Brill S, Shalev H, Rudich Z, and Shahar G
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- Humans, Universities, Cross-Sectional Studies, Chronic Pain
- Abstract
Objective: Relying on anthropomorphism research, Illness Personification Theory (ILL-PERF) posits that individuals living with a chronic illness ascribe human-like characteristics to their illness. Herein we examine the personification of chronic pain using a new measure: the Ben-Gurion University Illness Personification Scale (BGU-IPS). Method: Three samples of chronic pain patients (Sample 1 and 2 are distinct samples sharing similar characteristics, collected in the context of a cross-sectional design, Ns = 259, 263; Sample 3: a 2-waves longitudinal, N =163) completed the 12-item BGU-IPS, and measures of pain and related factors. Results: An orthogonal, two-factor structure was revealed for the BGU-IPS pertaining to negative vs. positive personifications. Negative personification was associated with pain intensity and illness-related distress (e.g., depression and low adjustment to pain). Positive personification was correlated with hope, pain-related sense of control, and low depression. However, positive personification also augmented the associations between negative personification and several risk factors. Conclusions : Pain personification, particularly as assessed via the BGU-IPS, plays a major role in (mal)adaptation to chronic pain.
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- 2023
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45. Predictors of residual disease following pediatric thyroglossal duct cyst excision.
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Gilony D, Shaked O, Tsur N, Raveh E, and Hod R
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- Child, Humans, Retrospective Studies, Reoperation, Postoperative Complications epidemiology, Postoperative Complications surgery, Thyroglossal Cyst surgery, Thyroglossal Cyst diagnosis, Cutaneous Fistula surgery
- Abstract
Objectives: Residual thyroglossal duct cyst (TGDC) following surgical excision is not uncommon. This study aimed to search for risk factors for residual disease that either required revision surgery or were resolved with only conservative treatment and follow up., Methods: A retrospective study of consecutive children who underwent surgical excision for thyroglossal duct cysts between 2008 and 2021 at Schneider Children's Medical Center of Israel, a tertiary referral center in Israel., Results: Out of 102 children, 54 (53 %) had an uneventful recovery, 32 (31 %) had post-operative complications which were managed without revision surgery, and 16 (16 %) underwent revision surgery. A comparison of the three groups showed that children who had early post-operative complications (up to one month) were more likely to respond to conservative treatment (57 %). In contrast children with late complications had a higher probability (59 %) of undergoing revision surgery. The presence of a pre-operative cutaneous fistula was significantly associated with revision surgery (p = 0.012). In addition, children with no prior history of neck infection were more likely to have an uneventful recovery (p = 0.005)., Conclusions: TGDC disease has a wide range of clinical presentations both before and after surgery. A significant percentage of children with persistent post-operative symptoms may resolve without revision surgery. The presence of a pre-operative cutaneous fistula and late post-operative complications are the main risk factors for revision surgery., (Copyright © 2023. Published by Elsevier Inc.)
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- 2023
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46. Ultrasonographic Features of Salivary Glands after Radioiodine Therapy in Patients with Thyroid Cancer.
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Tsur N, Avishai G, Alkan U, Hod R, Shpitzer T, Bitton E, and Gilat H
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- Humans, Iodine Radioisotopes adverse effects, Retrospective Studies, Salivary Glands diagnostic imaging, Thyroid Cancer, Papillary diagnostic imaging, Thyroid Cancer, Papillary radiotherapy, Thyroid Cancer, Papillary surgery, Thyroidectomy, Thyroid Neoplasms diagnostic imaging, Thyroid Neoplasms radiotherapy, Thyroid Neoplasms surgery
- Abstract
Objective: Chronic sialadenitis is the most common complication of radioactive iodine (RAI) treatment. The aim of the study was to ascertain sonographic features of the major salivary glands in patients with papillary thyroid cancer (PTC) treated with RAI., Methods: The database of a tertiary medical center was retrospectively searched for consecutive patients who underwent total thyroidectomy for PTC in 2011-2020 with ultrasound follow-up after 1 year. Changes in ultrasound features of the major salivary glands were compared between patients treated or not treated with RAI postoperatively., Results: The cohort included 158 patients, of whom 109 (69%) were treated postoperatively with RAI (mean dose, 131 mCi) and 49 were not (control group). Sonographic changes were observed in the major salivary glands in 43% of the study group and 18% of the control group (p = 0.002), including coarse echotexture, decreased echogenicity, fibrosis, and atrophy. Higher RAI doses were significantly correlated with the prevalence and severity of glandular changes (p < 0.0001)., Conclusion: RAI treatment following thyroidectomy is associated with a dose-response effect and adverse changes in the major salivary glands and should be prescribed carefully., Level of Evidence: 4 Laryngoscope, 133:1271-1275, 2023., (© 2022 The American Laryngological, Rhinological and Otological Society, Inc.)
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- 2023
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47. Thyroid-split tracheostomy: short- and long-term outcomes.
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Tsur N, Segal E, Yosefof E, Koch N, Zeeman I, Reifen E, Wiesel O, Bachar G, and Najjar E
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- Humans, Adolescent, Adult, Treatment Outcome, Postoperative Complications epidemiology, Postoperative Complications etiology, Reoperation, Retrospective Studies, Tracheostomy adverse effects, Thyroid Gland
- Abstract
Objective: Compare long-term outcomes of thyroid-split and standard thyroid-retraction tracheostomy in a large cohort., Methods: The healthcare database of a university-affiliated hospital was searched for past patients over 18 years of age from all of the hospital's wards on whom an ear, nose, and throat specialist performed a tracheostomy in the operating room between 2010 and 2020. Clinical data were extracted from the hospital and outpatient medical records. Life-threatening and non-life-threatening intra-operative and early and late post-operative adverse events in patients who underwent split-thyroid tracheostomy were compared with those who underwent standard tracheostomy., Results: There was no significant difference in intra-operative and early post-operative complications, hospitalisation length, or early reoperation and death rates between the 140 (28%) thyroid-split tracheostomy patients and the 354 (72%) standard tracheostomy patients, although the thyroid-split group had more non-decannulated patients and a longer operative time., Conclusions: Thyroid-split tracheostomy is safe and feasible. Compared to the standard procedure, it provides better exposure and a similar rate of complications, although its de-cannulation success rate is lower., (Copyright © 2023 Società Italiana di Otorinolaringoiatria e Chirurgia Cervico-Facciale, Rome, Italy.)
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- 2023
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48. Traumatic maxillofacial injuries: Patterns, outcomes, and long-term follow-up of a military cohort.
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Tsur N, Talmy T, Radomislensky I, Almog O, and Gendler S
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- Humans, Follow-Up Studies, Hospitalization, Retrospective Studies, Military Personnel, Maxillofacial Injuries, Skull Fractures
- Abstract
Background/aims: Maxillofacial trauma poses a distinct challenge on the modern battlefield, and data on its long-term implications are scarce. The aim of this study was to investigate maxillofacial injury characteristics, outcomes, and complications along the continuum of care among hospitalized military personnel from the pre-hospital setting through long-term rehabilitation., Materials and Methods: A registry-based study was undertaken of three national trauma and rehabilitation registries: The Israel Defense Forces Trauma Registry (IDF-TR), which records pre-hospital data. The Israeli National Trauma Registry for in-hospital data and the Israel Ministry of Defense Rehabilitation Department (MOD-RD) registry contain long-term disability data. The cohort comprised IDF soldiers who suffered maxillofacial injuries between 1997 and 2020., Results: A total of 672 patients with maxillofacial injuries were included in the study, and 6.4% of all trauma admissions were related to maxillofacial injuries. Of these, 366 (54%) were injured in non-military (NMC) circumstances, and 306 (46%) were wounded in military circumstances (MC). The mechanisms of injury were mainly traffic-related among the NMC group compared with an explosion in the MC group. Maxillofacial fractures were frequently associated with traumatic brain injuries with higher rates in the NMC group than in the MC group (55% vs. 30%, p < .001). In a multivariate analysis, zygomatic and orbital fractures were associated with higher odds of concomitant head injury. The most common categories of long-term disability included central nervous system disorders, skull injuries, epilepsy, hearing impairment, ophthalmologic conditions, and post-traumatic stress disorder., Conclusions: Maxillofacial injuries are often associated with concomitant traumatic brain injury. Long-term disabilities associated with these injuries included the central nervous system, hearing, ophthalmologic impairments, and post-traumatic stress disorder., (© 2022 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)
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- 2023
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49. "When I was a child, the doctor advised me to have sex more gently": The perceptions and experiences with the healthcare system as conveyed by adult survivors of child sexual abuse.
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Tsur N, Najjar AA, and Katz C
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- Adult, Humans, Child, Female, Survivors, Health Personnel, Delivery of Health Care, Child Abuse, Sexual, Physicians, Adult Survivors of Child Abuse, Child Abuse
- Abstract
Rationale: Extensive findings have illuminated the implications of child sexual abuse (CSA) for mental and physical health. Attention has been dedicated to the discrepancy between the high prevalence of CSA, and the lack of adequate CSA screening and trauma-informed care within healthcare systems., Objective: This study was designed to examine this discrepancy by providing CSA survivors' perspectives. Specifically, this study aims to uncover the perceptions and experiences of female survivors of CSA concerning their encounters with the healthcare system., Methods: Written narratives were collected from 53 female survivors of CSA as part of the Israeli Independent Public Inquiry into CSA, which were analyzed guided by an inductive thematic analysis., Results: This study's findings portrayed a complex scenery in which female survivors of CSA are concurrently dependent on healthcare services due to the CSA-related morbidity, yet they are hesitant and have difficulty approaching healthcare services. Additionally, the findings showed that the survivors of CSA described being perceived as mentally ill and distrustful; they also were encouraged to take excessive medication by healthcare providers, which resulted in many survivors of CSA avoiding further treatment. Furthermore, the survivors of CSA conveyed several clear messages to the healthcare system, all of which called for the urgent need to implement trauma-informed care., Conclusions: These findings underline the necessity of a paradigm shift in which health and illness are viewed in light of personal, interpersonal, and social contexts. Simply put, it is time for trauma-informed care to be extensively implemented in healthcare services., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2023. Published by Elsevier Ltd.)
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- 2023
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50. Post-Traumatic Orientation to Bodily Signals: A Systematic Literature Review.
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Tsur N and Talmon A
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- Humans, Stress Disorders, Post-Traumatic
- Abstract
Theoretical literature suggests that trauma and (PTSD) may instigate changes in the interpretation of bodily signals. Some findings support these inquiries, revealing that exposure to traumatic events and PTSD are associated with pain catastrophizing, body vigilance, fear of pain, and other manifestations of bodily perceptions and interpretations. However, these findings are not integrated into an inclusive empirically based conceptualization, thus leading to a limited comprehension of this phenomenon. This systematic literature review was conducted to synthesize the existing literature referring to orientation to bodily signals. Using Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, the review included a final of 48 manuscripts that addressed orientation to bodily signals among participants (aged 18 and above) and its potential associations with PTSD. The review revealed that most studies assessed one orientation manifestation, which was tested for its link to PTSD. The majority of the manuscripts were cross-sectional and included participants who faced combat, vehicle accidents, or various types of traumas. Only five manuscripts focused on interpersonal trauma and abuse. Most manuscripts reported significant correlations, revealing that trauma and PTSD are associated with a negative, catastrophic and frightful interpretation of bodily signals. These findings emphasize the need to encapsulate the various manifestations of orientation to bodily signals under a unified construct, as proposed by the term post-traumatic orientation to bodily signals . Further research is needed to illuminate the circumstances and processes by which trauma is implicated in post-traumatic orientation to bodily signals.
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- 2023
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