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1. Tensor-to-scalar ratio forecasts for extended LiteBIRD frequency configurations

Author

Fuskeland, U., Aumont, J., Aurlien, R., Baccigalupi, C., Banday, A. J., Eriksen, H. K., Errard, J., Génova-Santos, R. T., Hasebe, T., Hubmayr, J., Imada, H., Krachmalnicoff, N., Lamagna, L., Pisano, G., Poletti, D., Remazeilles, M., Thompson, K. L., Vacher, L., Wehus, I. K., Azzoni, S., Ballardini, M., Barreiro, R. B., Bartolo, N., Basyrov, A., Beck, D., Bersanelli, M., Bortolami, M., Brilenkov, M., Calabrese, E., Carones, A., Casas, F. J., Cheung, K., Chluba, J., Clark, S. E., Clermont, L., Columbro, F., Coppolecchia, A., D'Alessandro, G., de Bernardis, P., de Haan, T., de la Hoz, E., De Petris, M., Della Torre, S., Diego-Palazuelos, P., Finelli, F., Franceschet, C., Galloni, G., Galloway, M., Gerbino, M., Gervasi, M., Ghigna, T., Giardiello, S., Gjerløw, E., Gruppuso, A., Hargrave, P., Hattori, M., Hazumi, M., Hergt, L. T., Herman, D., Herranz, D., Hivon, E., Hoang, T. D., Kohri, K., Lattanzi, M., Lee, A. T., Leloup, C., Levrier, F., Lonappan, A. I., Luzzi, G., Maffei, B., Martínez-González, E., Masi, S., Matarrese, S., Matsumura, T., Migliaccio, M., Montier, L., Morgante, G., Mot, B., Mousset, L., Nagata, R., Namikawa, T., Nati, F., Natoli, P., Nerval, S., Novelli, A., Pagano, L., Paiella, A., Paoletti, D., Pascual-Cisneros, G., Patanchon, G., Pelgrims, V., Piacentini, F., Piccirilli, G., Polenta, G., Puglisi, G., Raffuzzi, N., Ritacco, A., Rubino-Martin, J. A., Savini, G., Scott, D., Sekimoto, Y., Shiraishi, M., Signorelli, G., Stever, S. L., Stutzer, N., Sullivan, R. M., Takakura, H., Terenzi, L., Thommesen, H., Tristram, M., Tsuji, M., Vielva, P., Weller, J., Westbrook, B., Weymann-Despres, G., Wollack, E. J., and Zannoni, M.

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

LiteBIRD is a planned JAXA-led CMB B-mode satellite experiment aiming for launch in the late 2020s, with a primary goal of detecting the imprint of primordial inflationary gravitational waves. Its current baseline focal-plane configuration includes 15 frequency bands between 40 and 402 GHz, fulfilling the mission requirements to detect the amplitude of gravitational waves with the total uncertainty on the tensor-to-scalar ratio, $\delta r$, down to $\delta r<0.001$. A key aspect of this performance is accurate astrophysical component separation, and the ability to remove polarized thermal dust emission is particularly important. In this paper we note that the CMB frequency spectrum falls off nearly exponentially above 300 GHz relative to the thermal dust SED, and a relatively minor high frequency extension can therefore result in even lower uncertainties and better model reconstructions. Specifically, we compare the baseline design with five extended configurations, while varying the underlying dust modeling, in each of which the HFT (High-Frequency Telescope) frequency range is shifted logarithmically towards higher frequencies, with an upper cutoff ranging between 400 and 600 GHz. In each case, we measure the tensor-to-scalar ratio $r$ uncertainty and bias using both parametric and minimum-variance component-separation algorithms. When the thermal dust sky model includes a spatially varying spectral index and temperature, we find that the statistical uncertainty on $r$ after foreground cleaning may be reduced by as much as 30--50 % by extending the upper limit of the frequency range from 400 to 600 GHz, with most of the improvement already gained at 500 GHz. We also note that a broader frequency range leads to better ability to discriminate between models through higher $\chi^2$ sensitivity. (abridged), Comment: 18 pages, 13 figures. Published in A&A

Published
2023
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3. Probing Cosmic Inflation with the LiteBIRD Cosmic Microwave Background Polarization Survey

Author

LiteBIRD Collaboration, Allys, E., Arnold, K., Aumont, J., Aurlien, R., Azzoni, S., Baccigalupi, C., Banday, A. J., Banerji, R., Barreiro, R. B., Bartolo, N., Bautista, L., Beck, D., Beckman, S., Bersanelli, M., Boulanger, F., Brilenkov, M., Bucher, M., Calabrese, E., Campeti, P., Carones, A., Casas, F. J., Catalano, A., Chan, V., Cheung, K., Chinone, Y., Clark, S. E., Columbro, F., D'Alessandro, G., de Bernardis, P., de Haan, T., de la Hoz, E., De Petris, M., Della Torre, S., Diego-Palazuelos, P., Dobbs, M., Dotani, T., Duval, J. M., Elleflot, T., Eriksen, H. K., Errard, J., Essinger-Hileman, T., Finelli, F., Flauger, R., Franceschet, C., Fuskeland, U., Galloway, M., Ganga, K., Gerbino, M., Gervasi, M., Génova-Santos, R. T., Ghigna, T., Giardiello, S., Gjerløw, E., Grain, J., Grupp, F., Gruppuso, A., Gudmundsson, J. E., Halverson, N. W., Hargrave, P., Hasebe, T., Hasegawa, M., Hazumi, M., Henrot-Versillé, S., Hensley, B., Hergt, L. T., Herman, D., Hivon, E., Hlozek, R. A., Hornsby, A. L., Hoshino, Y., Hubmayr, J., Ichiki, K., Iida, T., Imada, H., Ishino, H., Jaehnig, G., Katayama, N., Kato, A., Keskitalo, R., Kisner, T., Kobayashi, Y., Kogut, A., Kohri, K., Komatsu, E., Komatsu, K., Konishi, K., Krachmalnicoff, N., Kuo, C. L., Lamagna, L., Lattanzi, M., Lee, A. T., Leloup, C., Levrier, F., Linder, E., Luzzi, G., Macias-Perez, J., Maciaszek, T., Maffei, B., Maino, D., Mandelli, S., Martínez-González, E., Masi, S., Massa, M., Matarrese, S., Matsuda, F. T., Matsumura, T., Mele, L., Migliaccio, M., Minami, Y., Moggi, A., Montgomery, J., Montier, L., Morgante, G., Mot, B., Nagano, Y., Nagasaki, T., Nagata, R., Nakano, R., Namikawa, T., Nati, F., Natoli, P., Nerval, S., Noviello, F., Odagiri, K., Oguri, S., Ohsaki, H., Pagano, L., Paiella, A., Paoletti, D., Passerini, A., Patanchon, G., Piacentini, F., Piat, M., Pisano, G., Polenta, G., Poletti, D., Prouvé, T., Puglisi, G., Rambaud, D., Raum, C., Realini, S., Reinecke, M., Remazeilles, M., Ritacco, A., Roudil, G., Rubino-Martin, J. A., Russell, M., Sakurai, H., Sakurai, Y., Sasaki, M., Scott, D., Sekimoto, Y., Shinozaki, K., Shiraishi, M., Shirron, P., Signorelli, G., Spinella, F., Stever, S., Stompor, R., Sugiyama, S., Sullivan, R. M., Suzuki, A., Svalheim, T. L., Switzer, E., Takaku, R., Takakura, H., Takase, Y., Tartari, A., Terao, Y., Thermeau, J., Thommesen, H., Thompson, K. L., Tomasi, M., Tominaga, M., Tristram, M., Tsuji, M., Tsujimoto, M., Vacher, L., Vielva, P., Vittorio, N., Wang, W., Watanuki, K., Wehus, I. K., Weller, J., Westbrook, B., Wilms, J., Winter, B., Wollack, E. J., Yumoto, J., and Zannoni, M.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

LiteBIRD, the Lite (Light) satellite for the study of B-mode polarization and Inflation from cosmic background Radiation Detection, is a space mission for primordial cosmology and fundamental physics. The Japan Aerospace Exploration Agency (JAXA) selected LiteBIRD in May 2019 as a strategic large-class (L-class) mission, with an expected launch in the late 2020s using JAXA's H3 rocket. LiteBIRD is planned to orbit the Sun-Earth Lagrangian point L2, where it will map the cosmic microwave background (CMB) polarization over the entire sky for three years, with three telescopes in 15 frequency bands between 34 and 448 GHz, to achieve an unprecedented total sensitivity of 2.2$\mu$K-arcmin, with a typical angular resolution of 0.5$^\circ$ at 100 GHz. The primary scientific objective of LiteBIRD is to search for the signal from cosmic inflation, either making a discovery or ruling out well-motivated inflationary models. The measurements of LiteBIRD will also provide us with insight into the quantum nature of gravity and other new physics beyond the standard models of particle physics and cosmology. We provide an overview of the LiteBIRD project, including scientific objectives, mission and system requirements, operation concept, spacecraft and payload module design, expected scientific outcomes, potential design extensions and synergies with other projects., Comment: 155 pages, accepted for publication in PTEP

Published
2022
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4. Search for dark matter annihilation signals from unidentified Fermi-LAT objects with H.E.S.S

Author

Collaboration, H. E. S. S., Abdallah, H., Aharonian, F., Benkhali, F. Ait, Angüner, E. O., Arcaro, C., Armand, C., Armstrong, T., Ashkar, H., Backes, M., Baghmanyan, V., Martins, V. Barbosa, Barnacka, A., Barnard, M., Becherini, Y., Berge, D., Bernlöhr, K., Bi, B., Böttcher, M., Boisson, C., Bolmont, J., de Lavergne, M. de Bony, Breuhaus, M., Brose, R., Brun, F., Bulik, T., Bylund, T., Cangemi, F., Caroff, S., Casanova, S., Chambery, P., Chand, J. Catalano T., Chen, A., Cotter, G., Curylo, M., Dalgleish, H., Mbarubucyeye, J. Damascene, Davids, I. D., Davies, J., Devin, J., Djannati-Ataï, A., Dmytriiev, A., Donath, A., Doroshenko, V., Dreyer, L., Plessis, L. Du, Duffy, C., Egberts, K., Einecke, S., Emery, G., Ernenwein, J. -P., Feijen, K., Fegan, S., Fiasson, A., de Clairfontaine, G. Fichet, Fontaine, G., Funk, S., Füßling, M., Gabici, S., Gallant, Y. A., Giavitto, G., Giunti, L., Glawion, D., Glicenstein, J. F., Grondin, M. -H., Hattingh, S., Haupt, M., Hermann, G., Hinton, J. A., Hofmann, W., Hoischen, C., Holch, T. L., Holler, M., Hörbe, M., Horns, D., Huang, Z., Huber, D., Jamrozy, M., Jankowsky, D., Jankowsky, F., Joshi, V., Jung-Richardt, I., Kasai, E., Katarzyński, K., Katz, U., Khangulyan, D., Khèlifi, B., Klepser, S., Kluzniak, W., Komin, Nu., Konno, R., Kosack, K., Kostunin, D., Kreter, M., Mezek, G. Kukec, Kundu, A., Lamanna, G., Stum, S. Le, Lemière, A., Lemoine-Goumard, M., Lenain, J. -P., Leuschner, F., Levy, C., Lohse, T., Luashvili, A., Lypova, I., Mackey, J., Majumdar, J., Malyshev, D., Marandon, V., Marchegiani, P., Marcowith, A., Mares, A., Martì-Devesa, G., Marx, R., Maurin, G., Meintjes, P. J., Meyer, M., Mitchell, A., Moderski, R., Mohrmann, L., Montanari, A., Moore, C., Morris, P., Moulin, E., Muller, J., Murach, T., Nakashima, K., Nayerhoda, A., de Naurois, M., Ndiyavala, H., Niemiec, J., Noel, A., Oberholzer, L., O'Brien, P., Ohm, S., Olivera-Nieto, L., Wilhelmi, E. de Ona, Ostrowski, M., Panter, M., Panny, S., Parsons, R. D., Peron, G., Pita, S., Poireau, V., Prokhorov, D. A., Prokoph, H., Pühlhofer, G., Punch, M., Quirrenbach, A., Reichherzer, P., Reimer, A., Reimer, O., Remy, Q., Renaud, M., Rieger, F., Romoli, C., Rowell, G., Rudak, B., Ricarte, H. Rueda, Ruiz-Velasco, E., Sahakian, V., Sailer, S., Salzmann, H., Sanchez, D. A., Santangelo, A., Sasaki, M., Schüssler, F., Schutte, H. M., Schwanke, U., Senniappan, M., Seyffert, A. S., Shapopi, J. N. S., Shiningayamwe, K., Simoni, R., Sinha, A., Sol, H., Spackman, H., Specovius, A., Spencer, S., Spir-Jacob, M., Stawarz, L., Sun, L., Steenkamp, R., Stegmann, C., Steinmassl, S., Steppa, C., Takahashi, T., Tanaka, T., Tavernier, T., Taylor, A. M., Terrier, R., Morgan, C. Thorpe, Thiersen, J. H. E., Tluczykont, M., Tomankova, L., Trichard, C., Tsirou, M., Tsuji, M., Tuffs, R., Uchiyama, Y., van der Walt, D. J., van Eldik, C., van Rensburg, C., van Soelen, B., Vasileiadis, G., Veh, J., Venter, C., Viana, A., Vincent, P., Vink, J., Völk, H. J., Wagner, S. J., Werner, F., White, R., Wierzcholska, A., Wong, Yu Wun, Yassin, H., Yusafzai, A., Zacharias, M., Zanin, R., Zargaryan, D., Zdziarski, A. A., Zech, A., Zhu, S., Zmija, A., Zorn, J., Zouari, S., and Zywucka, N.

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

Cosmological $N$-body simulations show that Milky Way-sized galaxies harbor a population of unmerged dark matter subhalos. These subhalos could shine in gamma-rays and be eventually detected in gamma-ray surveys as unidentified sources. We performed a thorough selection among unidentified Fermi-LAT Objects (UFOs) to identify them as possible TeV-scale dark matter subhalo candidates. We search for very-high-energy (E $\gtrsim$ 100 GeV) gamma-ray emissions using H.E.S.S. observations towards four selected UFOs. Since no significant very-high-energy gamma-ray emission is detected in any dataset of the four observed UFOs nor in the combined UFO dataset, strong constraints are derived on the product of the velocity-weighted annihilation cross section $\langle \sigma v \rangle$ by the $J$-factor for the dark matter models. The 95% C.L. observed upper limits derived from combined H.E.S.S. observations reach $\langle \sigma v \rangle J$ values of 3.7$\times$10$^{-5}$ and 8.1$\times$10$^{-6}$ GeV$^2$cm$^{-2}$s$^{-1}$ in the $W^+W^-$ and $\tau^+\tau^-$ channels, respectively, for a 1 TeV dark matter mass. Focusing on thermal WIMPs, the H.E.S.S. constraints restrict the $J$-factors to lie in the range 6.1$\times$10$^{19}$ - 2.0$\times$10$^{21}$ GeV$^2$cm$^{-5}$, and the masses to lie between 0.2 and 6 TeV in the $W^+W^-$ channel. For the $\tau^+\tau^-$ channel, the $J$-factors lie in the range 7.0$\times$10$^{19}$ - 7.1$\times$10$^{20}$ GeV$^2$cm$^{-5}$ and the masses lie between 0.2 and 0.5 TeV. Assuming model-dependent predictions from cosmological N-body simulations on the $J$-factor distribution for Milky Way-sized galaxies, the dark matter models with masses greater than 0.3 TeV for the UFO emissions can be ruled out at high confidence level., Comment: 11 pages, 7 figures, matches accepted version in The Astrophysical Journal

Published
2021
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5. In-flight polarization angle calibration for LiteBIRD: blind challenge and cosmological implications

Author

collaboration, The LiteBIRD, Krachmalnicoff, N, Matsumura, T, de la Hoz, E, Basak, S, Gruppuso, A, Minami, Y, Baccigalupi, C, Komatsu, E, Martínez-González, E, Vielva, P, Aumont, J, Aurlien, R, Azzoni, S, Banday, AJ, Barreiro, RB, Bartolo, N, Bersanelli, M, Calabrese, E, Carones, A, Casas, FJ, Cheung, K, Chinone, Y, Columbro, F, de Bernardis, P, Diego-Palazuelos, P, Errard, J, Finelli, F, Fuskeland, U, Galloway, M, Genova-Santos, RT, Gerbino, M, Ghigna, T, Giardiello, S, Gjerløw, E, Hazumi, M, Henrot-Versillé, S, Kisner, T, Lamagna, L, Lattanzi, M, Levrier, F, Luzzi, G, Maino, D, Masi, S, Migliaccio, M, Montier, L, Morgante, G, Mot, B, Nagata, R, Nati, F, Natoli, P, Pagano, L, Paiella, A, Paoletti, D, Patanchon, G, Piacentini, F, Polenta, G, Poletti, D, Puglisi, G, Remazeilles, M, Rubino-Martin, J, Sasaki, M, Shiraishi, M, Signorelli, G, Stever, S, Tartari, A, Tristram, M, Tsuji, M, Vacher, L, Wehus, IK, and Zannoni, M

Subjects
Astronomical and Space Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Nuclear & Particles Physics
Abstract

We present a demonstration of the in-flight polarization angle calibration for the JAXA/ISAS second strategic large class mission, LiteBIRD, and estimate its impact on the measurement of the tensor-to-scalar ratio parameter, r, using simulated data. We generate a set of simulated sky maps with CMB and polarized foreground emission, and inject instrumental noise and polarization angle offsets to the 22 (partially overlapping) LiteBIRD frequency channels. Our in-flight angle calibration relies on nulling the EB cross correlation of the polarized signal in each channel. This calibration step has been carried out by two independent groups with a blind analysis, allowing an accuracy of the order of a few arc-minutes to be reached on the estimate of the angle offsets. Both the corrected and uncorrected multi-frequency maps are propagated through the foreground cleaning step, with the goal of computing clean CMB maps. We employ two component separation algorithms, the Bayesian-Separation of Components and Residuals Estimate Tool (B-SeCRET), and the Needlet Internal Linear Combination (NILC). We find that the recovered CMB maps obtained with algorithms that do not make any assumptions about the foreground properties, such as NILC, are only mildly affected by the angle miscalibration. However, polarization angle offsets strongly bias results obtained with the parametric fitting method. Once the miscalibration angles are corrected by EB nulling prior to the component separation, both component separation algorithms result in an unbiased estimation of the r parameter. While this work is motivated by the conceptual design study for LiteBIRD, its framework can be broadly applied to any CMB polarization experiment. In particular, the combination of simulation plus blind analysis provides a robust forecast by taking into account not only detector sensitivity but also systematic effects.

Published
2022

6. Overview of the Medium and High Frequency Telescopes of the LiteBIRD satellite mission

Author

Montier, L., Mot, B., de Bernardis, P., Maffei, B., Pisano, G., Columbro, F., Gudmundsson, J. E., Henrot-Versillé, S., Lamagna, L., Montgomery, J., Prouvé, T., Russell, M., Savini, G., Stever, S., Thompson, K. L., Tsujimoto, M., Tucker, C., Westbrook, B., Ade, P. A. R., Adler, A., Allys, E., Arnold, K., Auguste, D., Aumont, J., Aurlien, R., Austermann, J., Baccigalupi, C., Banday, A. J., Banerji, R., Barreiro, R. B., Basak, S., Beall, J., Beck, D., Beckman, S., Bermejo, J., Bersanelli, M., Bonis, J., Borrill, J., Boulanger, F., Bounissou, S., Brilenkov, M., Brown, M., Bucher, M., Calabrese, E., Campeti, P., Carones, A., Casas, F. J., Challinor, A., Chan, V., Cheung, K., Chinone, Y., Cliche, J. F., Colombo, L., Cubas, J., Cukierman, A., Curtis, D., D'Alessandro, G., Dachlythra, N., De Petris, M., Dickinson, C., Diego-Palazuelos, P., Dobbs, M., Dotani, T., Duband, L., Duff, S., Duval, J. M., Ebisawa, K., Elleflot, T., Eriksen, H. K., Errard, J., Essinger-Hileman, T., Finelli, F., Flauger, R., Franceschet, C., Fuskeland, U., Galloway, M., Ganga, K., Gao, J. R., Genova-Santos, R., Gerbino, M., Gervasi, M., Ghigna, T., Gjerløw, E., Gradziel, M. L., Grain, J., Grupp, F., Gruppuso, A., de Haan, T., Halverson, N. W., Hargrave, P., Hasebe, T., Hasegawa, M., Hattori, M., Hazumi, M., Herman, D., Herranz, D., Hill, C. A., Hilton, G., Hirota, Y., Hivon, E., Hlozek, R. A., Hoshino, Y., de la Hoz, E., Hubmayr, J., Ichiki, K., Iida, T., Imada, H., Ishimura, K., Ishino, H., Jaehnig, G., Kaga, T., Kashima, S., Katayama, N., Kato, A., Kawasaki, T., Keskitalo, R., Kisner, T., Kobayashi, Y., Kogiso, N., Kogut, A., Kohri, K., Komatsu, E., Komatsu, K., Konishi, K., Krachmalnicoff, N., Kreykenbohm, I., Kuo, C. L., Kushino, A., Lanen, J. V., Lattanzi, M., Lee, A. T., Leloup, C., Levrier, F., Linder, E., Louis, T., Luzzi, G., Maciaszek, T., Maino, D., Maki, M., Mandelli, S., Martinez-Gonzalez, E., Masi, S., Matsumura, T., Mennella, A., Migliaccio, M., Minami, Y., Mitsuda, K., Morgante, G., Murata, Y., Murphy, J. A., Nagai, M., Nagano, Y., Nagasaki, T., Nagata, R., Nakamura, S., Namikawa, T., Natoli, P., Nerval, S., Nishibori, T., Nishino, H., O'Sullivan, C., Ogawa, H., Oguri, S., Ohsaki, H., Ohta, I. S., Okada, N., Pagano, L., Paiella, A., Paoletti, D., Patanchon, G., Peloton, J., Piacentini, F., Polenta, G., Poletti, D., Puglisi, G., Rambaud, D., Raum, C., Realini, S., Reinecke, M., Remazeilles, M., Ritacco, A., Roudil, G., Rubino-Martin, J. A., Sakurai, H., Sakurai, Y., Sandri, M., Sasaki, M., Scott, D., Seibert, J., Sekimoto, Y., Sherwin, B., Shinozaki, K., Shiraishi, M., Shirron, P., Signorelli, G., Smecher, G., Stompor, R., Sugai, H., Sugiyama, S., Suzuki, A., Suzuki, J., Svalheim, T. L., Switzer, E., Takaku, R., Takakura, H., Takakura, S., Takase, Y., Takeda, Y., Tartari, A., Taylor, E., Terao, Y., Thommesen, H., Thorne, B., Toda, T., Tomasi, M., Tominaga, M., Trappe, N., Tristram, M., Tsuji, M., Ullom, J., Vermeulen, G., Vielva, P., Villa, F., Vissers, M., Vittorio, N., Wehus, I., Weller, J., Wilms, J., Winter, B., Wollack, E. J., Yamasaki, N. Y., Yoshida, T., Yumoto, J., Zannoni, M., and Zonca, A.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

LiteBIRD is a JAXA-led Strategic Large-Class mission designed to search for the existence of the primordial gravitational waves produced during the inflationary phase of the Universe, through the measurements of their imprint onto the polarization of the cosmic microwave background (CMB). These measurements, requiring unprecedented sensitivity, will be performed over the full sky, at large angular scales, and over 15 frequency bands from 34GHz to 448GHz. The LiteBIRD instruments consist of three telescopes, namely the Low-, Medium- and High-Frequency Telescope (respectively LFT, MFT and HFT). We present in this paper an overview of the design of the Medium-Frequency Telescope (89-224GHz) and the High-Frequency Telescope (166-448GHz), the so-called MHFT, under European responsibility, which are two cryogenic refractive telescopes cooled down to 5K. They include a continuous rotating half-wave plate as the first optical element, two high-density polyethylene (HDPE) lenses and more than three thousand transition-edge sensor (TES) detectors cooled to 100mK. We provide an overview of the concept design and the remaining specific challenges that we have to face in order to achieve the scientific goals of LiteBIRD., Comment: SPIE Conference

Published
2021
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7. LiteBIRD: JAXA's new strategic L-class mission for all-sky surveys of cosmic microwave background polarization

Author

Hazumi, M., Ade, P. A. R., Adler, A., Allys, E., Arnold, K., Auguste, D., Aumont, J., Aurlien, R., Austermann, J., Baccigalupi, C., Banday, A. J., Banjeri, R., Barreiro, R. B., Basak, S., Beall, J., Beck, D., Beckman, S., Bermejo, J., de Bernardis, P., Bersanelli, M., Bonis, J., Borrill, J., Boulanger, F., Bounissou, S., Brilenkov, M., Brown, M., Bucher, M., Calabrese, E., Campeti, P., Carones, A., Casas, F. J., Challinor, A., Chan, V., Cheung, K., Chinone, Y., Cliche, J. F., Colombo, L., Columbro, F., Cubas, J., Cukierman, A., Curtis, D., D'Alessandro, G., Dachlythra, N., De Petris, M., Dickinson, C., Diego-Palazuelos, P., Dobbs, M., Dotani, T., Duband, L., Duff, S., Duval, J. M., Ebisawa, K., Elleflot, T., Eriksen, H. K., Errard, J., Essinger-Hileman, T., Finelli, F., Flauger, R., Franceschet, C., Fuskeland, U., Galloway, M., Ganga, K., Gao, J. R., Genova-Santos, R., Gerbino, M., Gervasi, M., Ghigna, T., Gjerløw, E., Gradziel, M. L., Grain, J., Grupp, F., Gruppuso, A., Gudmundsson, J. E., de Haan, T., Halverson, N. W., Hargrave, P., Hasebe, T., Hasegawa, M., Hattori, M., Henrot-Versillé, S., Herman, D., Herranz, D., Hill, C. A., Hilton, G., Hirota, Y., Hivon, E., Hlozek, R. A., Hoshino, Y., de la Hoz, E., Hubmayr, J., Ichiki, K., Iida, T., Imada, H., Ishimura, K., Ishino, H., Jaehnig, G., Kaga, T., Kashima, S., Katayama, N., Kato, A., Kawasaki, T., Keskitalo, R., Kisner, T., Kobayashi, Y., Kogiso, N., Kogut, A., Kohri, K., Komatsu, E., Komatsu, K., Konishi, K., Krachmalnicoff, N., Kreykenbohm, I., Kuo, C. L., Kushino, A., Lamagna, L., Lanen, J. V., Lattanzi, M., Lee, A. T., Leloup, C., Levrier, F., Linder, E., Louis, T., Luzzi, G., Maciaszek, T., Maffei, B., Maino, D., Maki, M., Mandelli, S., Martinez-Gonzalez, E., Masi, S., Matsumura, T., Mennella, A., Migliaccio, M., Minami, Y., Mitsuda, K., Montgomery, J., Montier, L., Morgante, G., Mot, B., Murata, Y., Murphy, J. A., Nagai, M., Nagano, Y., Nagasaki, T., Nagata, R., Nakamura, S., Namikawa, T., Natoli, P., Nerval, S., Nishibori, T., Nishino, H., Noviello, F., O'Sullivan, C., Ogawa, H., Oguri, S., Ohsaki, H., Ohta, I. S., Okada, N., Pagano, L., Paiella, A., Paoletti, D., Patanchon, G., Peloton, J., Piacentini, F., Pisano, G., Polenta, G., Poletti, D., Prouvé, T., Puglisi, G., Rambaud, D., Raum, C., Realini, S., Reinecke, M., Remazeilles, M., Ritacco, A., Roudil, G., Rubino-Martin, J. A., Russell, M., Sakurai, H., Sakurai, Y., Sandri, M., Sasaki, M., Savini, G., Scott, D., Seibert, J., Sekimoto, Y., Sherwin, B., Shinozaki, K., Shiraishi, M., Shirron, P., Signorelli, G., Smecher, G., Stever, S., Stompor, R., Sugai, H., Sugiyama, S., Suzuki, A., Suzuki, J., Svalheim, T. L., Switzer, E., Takaku, R., Takakura, H., Takakura, S., Takase, Y., Takeda, Y., Tartari, A., Taylor, E., Terao, Y., Thommesen, H., Thompson, K. L., Thorne, B., Toda, T., Tomasi, M., Tominaga, M., Trappe, N., Tristram, M., Tsuji, M., Tsujimoto, M., Tucker, C., Ullom, J., Vermeulen, G., Vielva, P., Villa, F., Vissers, M., Vittorio, N., Wehus, I., Weller, J., Westbrook, B., Wilms, J., Winter, B., Wollack, E. J., Yamasaki, N. Y., Yoshida, T., Yumoto, J., Zannoni, M., and Zonca, A.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - Cosmology and Nongalactic Astrophysics, General Relativity and Quantum Cosmology, High Energy Physics - Experiment, High Energy Physics - Phenomenology
Abstract

LiteBIRD, the Lite (Light) satellite for the study of B-mode polarization and Inflation from cosmic background Radiation Detection, is a space mission for primordial cosmology and fundamental physics. JAXA selected LiteBIRD in May 2019 as a strategic large-class (L-class) mission, with its expected launch in the late 2020s using JAXA's H3 rocket. LiteBIRD plans to map the cosmic microwave background (CMB) polarization over the full sky with unprecedented precision. Its main scientific objective is to carry out a definitive search for the signal from cosmic inflation, either making a discovery or ruling out well-motivated inflationary models. The measurements of LiteBIRD will also provide us with an insight into the quantum nature of gravity and other new physics beyond the standard models of particle physics and cosmology. To this end, LiteBIRD will perform full-sky surveys for three years at the Sun-Earth Lagrangian point L2 for 15 frequency bands between 34 and 448 GHz with three telescopes, to achieve a total sensitivity of 2.16 micro K-arcmin with a typical angular resolution of 0.5 deg. at 100GHz. We provide an overview of the LiteBIRD project, including scientific objectives, mission requirements, top-level system requirements, operation concept, and expected scientific outcomes., Comment: 20 pages, 9 figures

Published
2021
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8. Concept Design of Low Frequency Telescope for CMB B-mode Polarization satellite LiteBIRD

Author

Sekimoto, Y., Ade, P. A. R., Adler, A., Allys, E., Arnold, K., Auguste, D., Aumont, J., Aurlien, R., Austermann, J., Baccigalupi, C., Banday, A. J., Banerji, R., Barreiro, R. B., Basak, S., Beall, J., Beck, D., Beckman, S., Bermejo, J., de Bernardis, P., Bersanelli, M., Bonis, J., Borrill, J., Boulanger, F., Bounissou, S., Brilenkov, M., Brown, M., Bucher, M., Calabrese, E., Campeti, P., Carones, A., Casas, F. J., Challinor, A., Chan, V., Cheung, K., Chinone, Y., Cliche, J. F., Colombo, L., Columbro, F., Cubas, J., Cukierman, A., Curtis, D., D'Alessandro, G., Dachlythra, N., De Petris, M., Dickinson, C., Diego-Palazuelos, P., Dobbs, M., Dotani, T., Duband, L., Duff, S., Duval, J. M., Ebisawa, K., Elleflot, T., Eriksen, H. K., Errard, J., Essinger-Hileman, T., Finelli, F., Flauger, R., Franceschet, C., Fuskeland, U., Galloway, M., Ganga, K., Gao, J. R., Genova-Santos, R., Gerbino, M., Gervasi, M., Ghigna, T., Gjerløw, E., Gradziel, M. L., Grain, J., Grupp, F., Gruppuso, A., Gudmundsson, J. E., de Haan, T., Halverson, N. W., Hargrave, P., Hasebe, T., Hasegawa, M., Hattori, M., Hazumi, M., Henrot-Versillé, S., Herman, D., Herranz, D., Hill, C. A., Hilton, G., Hirota, Y., Hivon, E., Hlozek, R. A., Hoshino, Y., de la Hoz, E., Hubmayr, J., Ichiki, K., iida, T., Imada, H., Ishimura, K., Ishino, H., Jaehnig, G., Kaga, T., Kashima, S., Katayama, N., Kato, A., Kawasaki, T., Keskitalo, R., Kisner, T., Kobayashi, Y., Kogiso, N., Kogut, A., Kohri, K., Komatsu, E., Komatsu, K., Konishi, K., Krachmalnicoff, N., Kreykenbohm, I., Kuo, C. L., Kushino, A., Lamagna, L., Lanen, J. V., Lattanzi, M., Lee, A. T., Leloup, C., Levrier, F., Linder, E., Louis, T., Luzzi, G., Maciaszek, T., Maffei, B., Maino, D., Maki, M., Mandelli, S., Martinez-Gonzalez, E., Masi, S., Matsumura, T., Mennella, A., Migliaccio, M., Minanmi, Y., Mitsuda, K., Montgomery, J., Montier, L., Morgante, G., Mot, B., Murata, Y., Murphy, J. A., Nagai, M., Nagano, Y., Nagasaki, T., Nagata, R., Nakamura, S., Namikawa, T., Natoli, P., Nerval, S., Nishibori, T., Nishino, H., O'Sullivan, C., Ogawa, H., Oguri, S., Ohsaki, H., Ohta, I. S., Okada, N., Pagano, L., Paiella, A., Paoletti, D., Patanchon, G., Peloton, J., Piacentini, F., Pisano, G., Polenta, G., Poletti, D., Prouvé, T., Puglisi, G., Rambaud, D., Raum, C., Realini, S., Reinecke, M., Remazeilles, M., Ritacco, A., Roudil, G., Rubino-Martin, J. A., Russell, M., Sakurai, H., Sakurai, Y., Sandri, M., Sasaki, M., Savini, G., Scott, D., Seibert, J., Sherwin, B., Shinozaki, K., Shiraishi, M., Shirron, P., Signorelli, G., Smecher, G., Stever, S., Stompor, R., Sugai, H., Sugiyama, S., Suzuki, A., Suzuki, J., Svalheim, T. L., Switzer, E., Takaku, R., Takakura, H., Takakura, S., Takase, Y., Takeda, Y., Tartari, A., Taylor, E., Terao, Y., Thommesen, H., Thompson, K. L., Thorne, B., Toda, T., Tomasi, M., Tominaga, M., Trappe, N., Tristram, M., Tsuji, M., Tsujimoto, M., Tucker, C., Ullom, J., Vermeulen, G., Vielva, P., Villa, F., Vissers, M., Vittorio, N., Wehus, I., Weller, J., Westbrook, B., Wilms, J., Winter, B., Wollack, E. J., Yamasaki, N. Y., Yoshida, T., Yumoto, J., Zannoni, M., and Zonca, A.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

LiteBIRD has been selected as JAXA's strategic large mission in the 2020s, to observe the cosmic microwave background (CMB) $B$-mode polarization over the full sky at large angular scales. The challenges of LiteBIRD are the wide field-of-view (FoV) and broadband capabilities of millimeter-wave polarization measurements, which are derived from the system requirements. The possible paths of stray light increase with a wider FoV and the far sidelobe knowledge of $-56$ dB is a challenging optical requirement. A crossed-Dragone configuration was chosen for the low frequency telescope (LFT : 34--161 GHz), one of LiteBIRD's onboard telescopes. It has a wide field-of-view ($18^\circ \times 9^\circ$) with an aperture of 400 mm in diameter, corresponding to an angular resolution of about 30 arcminutes around 100 GHz. The focal ratio f/3.0 and the crossing angle of the optical axes of 90$^\circ$ are chosen after an extensive study of the stray light. The primary and secondary reflectors have rectangular shapes with serrations to reduce the diffraction pattern from the edges of the mirrors. The reflectors and structure are made of aluminum to proportionally contract from warm down to the operating temperature at $5\,$K. A 1/4 scaled model of the LFT has been developed to validate the wide field-of-view design and to demonstrate the reduced far sidelobes. A polarization modulation unit (PMU), realized with a half-wave plate (HWP) is placed in front of the aperture stop, the entrance pupil of this system. A large focal plane with approximately 1000 AlMn TES detectors and frequency multiplexing SQUID amplifiers is cooled to 100 mK. The lens and sinuous antennas have broadband capability. Performance specifications of the LFT and an outline of the proposed verification plan are presented., Comment: 21 pages, 14 figures

Published
2021
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9. Updated design of the CMB polarization experiment satellite LiteBIRD

Author

Sugai, H., Ade, P. A. R., Akiba, Y., Alonso, D., Arnold, K., Aumont, J., Austermann, J., Baccigalupi, C., Banday, A. J., Banerji, R., Barreiro, R. B., Basak, S., Beall, J., Beckman, S., Bersanelli, M., Borrill, J., Boulanger, F., Brown, M. L., Bucher, M., Buzzelli, A., Calabrese, E., Casas, F. J., Challinor, A., Chan, V., Chinone, Y., Cliche, J. -F., Columbro, F., Cukierman, A., Curtis, D., Danto, P., de Bernardis, P., de Haan, T., De Petris, M., Dickinson, C., Dobbs, M., Dotani, T., Duband, L., Ducout, A., Duff, S., Duivenvoorden, A., Duval, J. -M., Ebisawa, K., Elleflot, T., Enokida, H., Eriksen, H. K., Errard, J., Essinger-Hileman, T., Finelli, F., Flauger, R., Franceschet, C., Fuskeland, U., Ganga, K., Gao, J. -R., Génova-Santos, R., Ghigna, T., Gomez, A., Gradziel, M. L., Grain, J., Grupp, F., Gruppuso, A., Gudmundsson, J. E., Halverson, N. W., Hargrave, P., Hasebe, T., Hasegawa, M., Hattori, M., Hazumi, M., Henrot-Versille, S., Herranz, D., Hill, C., Hilton, G., Hirota, Y., Hivon, E., Hlozek, R., Hoang, D. -T., Hubmayr, J., Ichiki, K., Iida, T., Imada, H., Ishimura, K., Ishino, H., Jaehnig, G. C., Jones, M., Kaga, T., Kashima, S., Kataoka, Y., Katayama, N., Kawasaki, T., Keskitalo, R., Kibayashi, A., Kikuchi, T., Kimura, K., Kisner, T., Kobayashi, Y., Kogiso, N., Kogut, A., Kohri, K., Komatsu, E., Komatsu, K., Konishi, K., Krachmalnicoff, N., Kuo, C. L., Kurinsky, N., Kushino, A., Kuwata-Gonokami, M., Lamagna, L., Lattanzi, M., Lee, A. T., Linder, E., Maffei, B., Maino, D., Maki, M., Mangilli, A., Martínez-González, E., Masi, S., Mathon, R., Matsumura, T., Mennella, A., Migliaccio, M., Minami, Y., Mistuda, K., Molinari, D., Montier, L., Morgante, G., Mot, B., Murata, Y., Murphy, J. A., Nagai, M., Nagata, R., Nakamura, S., Namikawa, T., Natoli, P., Nerva, S., Nishibori, T., Nishino, H., Nomura, Y., Noviello, F., O'Sullivan, C., Ochi, H., Ogawa, H., Ohsaki, H., Ohta, I., Okada, N., Pagano, L., Paiella, A., Paoletti, D., Patanchon, G., Piacentini, F., Pisano, G., Polenta, G., Poletti, D., Prouvé, T., Puglisi, G., Rambaud, D., Raum, C., Realini, S., Remazeilles, M., Roudil, G., Rubiño-Martín, J. A., Russell, M., Sakurai, H., Sakurai, Y., Sandri, M., Savini, G., Scott, D., Sekimoto, Y., Sherwin, B. D., Shinozaki, K., Shiraishi, M., Shirron, P., Signorelli, G., Smecher, G., Spizzi, P., Stever, S. L., Stompor, R., Sugiyama, S., Suzuki, A., Suzuki, J., Switzer, E., Takaku, R., Takakura, H., Takakura, S., Takeda, Y., Taylor, A., Taylor, E., Terao, Y., Thompson, K. L., Thorne, B., Tomasi, M., Tomida, H., Trappe, N., Tristram, M., Tsuji, M., Tsujimoto, M., Tucker, C., Ullom, J., Uozumi, S., Utsunomiya, S., Van Lanen, J., Vermeulen, G., Vielva, P., Villa, F., Vissers, M., Vittorio, N., Voisin, F., Walker, I., Watanabe, N., Wehus, I., Weller, J., Westbrook, B., Winter, B., Wollack, E., Yamamoto, R., Yamasaki, N. Y., Yanagisawa, M., Yoshida, T., Yumoto, J., Zannoni, M., and Zonca, A.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

Recent developments of transition-edge sensors (TESs), based on extensive experience in ground-based experiments, have been making the sensor techniques mature enough for their application on future satellite CMB polarization experiments. LiteBIRD is in the most advanced phase among such future satellites, targeting its launch in Japanese Fiscal Year 2027 (2027FY) with JAXA's H3 rocket. It will accommodate more than 4000 TESs in focal planes of reflective low-frequency and refractive medium-and-high-frequency telescopes in order to detect a signature imprinted on the cosmic microwave background (CMB) by the primordial gravitational waves predicted in cosmic inflation. The total wide frequency coverage between 34GHz and 448GHz enables us to extract such weak spiral polarization patterns through the precise subtraction of our Galaxy's foreground emission by using spectral differences among CMB and foreground signals. Telescopes are cooled down to 5Kelvin for suppressing thermal noise and contain polarization modulators with transmissive half-wave plates at individual apertures for separating sky polarization signals from artificial polarization and for mitigating from instrumental 1/f noise. Passive cooling by using V-grooves supports active cooling with mechanical coolers as well as adiabatic demagnetization refrigerators. Sky observations from the second Sun-Earth Lagrangian point, L2, are planned for three years. An international collaboration between Japan, USA, Canada, and Europe is sharing various roles. In May 2019, the Institute of Space and Astronautical Science (ISAS), JAXA selected LiteBIRD as the strategic large mission No. 2., Comment: Journal of Low Temperature Physics, in press

Published
2020
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10. Sensitivity Modeling for LiteBIRD

Author

Hasebe, T., Ade, P. A. R., Adler, A., Allys, E., Alonso, D., Arnold, K., Auguste, D., Aumont, J., Aurlien, R., Austermann, J., Azzoni, S., Baccigalupi, C., Banday, A. J., Banerji, R., Barreiro, R. B., Bartolo, N., Basak, S., Battistelli, E., Bautista, L., Beall, J., Beck, D., Beckman, S., Benabed, K., Bermejo-Ballesteros, J., Bersanelli, M., Bonis, J., Borrill, J., Bouchet, F., Boulanger, F., Bounissou, S., Brilenkov, M., Brown, M. L., Bucher, M., Calabrese, E., Calvo, M., Campeti, P., Carones, A., Casas, F. J., Catalano, A., Challinor, A., Chan, V., Cheung, K., Chinone, Y., Cliche, J., Columbro, F., Coulton, W., Cubas, J., Cukierman, A., Curtis, D., D’Alessandro, G., Dachlythra, K., de Bernardis, P., de Haan, T., de la Hoz, E., De Petris, M., Torre, S. Della, Dickinson, C., Diego-Palazuelos, P., Dobbs, M., Dotani, T., Douillet, D., Duband, L., Ducout, A., Duff, S., Duval, J. M., Ebisawa, K., Elleflot, T., Eriksen, H. K., Errard, J., Essinger-Hileman, T., Finelli, F., Flauger, R., Franceschet, C., Fuskeland, U., Galli, S., Galloway, M., Ganga, K., Gao, J. R., Genova-Santos, R. T., Gerbino, M., Gervasi, M., Ghigna, T., Giardiello, S., Gjerløw, E., Gradziel, M. L., Grain, J., Grandsire, L., Grupp, F., Gruppuso, A., Gudmundsson, J. E., Halverson, N. W., Hamilton, J., Hargrave, P., Hasegawa, M., Hattori, M., Hazumi, M., Henrot-Versillé, S., Hergt, L. T., Herman, D., Herranz, D., Hill, C. A., Hilton, G., Hivon, E., Hlozek, R. A., Hoang, T. D., Hornsby, A. L., Hoshino, Y., Hubmayr, J., Ichiki, K., Iida, T., Imada, H., Ishimura, K., Ishino, H., Jaehnig, G., Jones, M., Kaga, T., Kashima, S., Katayama, N., Kato, A., Kawasaki, T., Keskitalo, R., Kisner, T., Kobayashi, Y., Kogiso, N., Kogut, A., Kohri, K., Komatsu, E., Komatsu, K., Konishi, K., Krachmalnicoff, N., Kreykenbohm, I., Kuo, C. L., Kushino, A., Lamagna, L., Lanen, J. V., Laquaniello, G., Lattanzi, M., Lee, A. T., Leloup, C., Levrier, F., Linder, E., Louis, T., Luzzi, G., Macias-Perez, J., Maciaszek, T., Maffei, B., Maino, D., Maki, M., Mandelli, S., Maris, M., Martínez-González, E., Masi, S., Massa, M., Matarrese, S., Matsuda, F. T., Matsumura, T., Mele, L., Mennella, A., Migliaccio, M., Minami, Y., Mitsuda, K., Moggi, A., Monfardini, A., Montgomery, J., Montier, L., Morgante, G., Mot, B., Murata, Y., Murphy, J. A., Nagai, M., Nagano, Y., Nagasaki, T., Nagata, R., Nakamura, S., Nakano, R., Namikawa, T., Nati, F., Natoli, P., Nerval, S., Nishibori, T., Nishino, H., Noviello, F., O’Sullivan, C., Odagiri, K., Ogawa, H., Ogawa, H., Oguri, S., Ohsaki, H., Ohta, I. S., Okada, N., Okada, N., Pagano, L., Paiella, A., Paoletti, D., Passerini, A., Patanchon, G., Pelgrim, V., Peloton, J., Piacentini, F., Piat, M., Pisano, G., Polenta, G., Poletti, D., Prouvé, T., Puglisi, G., Rambaud, D., Raum, C., Realini, S., Reinecke, M., Remazeilles, M., Ritacco, A., Roudil, G., Rubino-Martin, J., Russell, M., Sakurai, H., Sakurai, Y., Sandri, M., Sasaki, M., Savini, G., Scott, D., Seibert, J., Sekimoto, Y., Sherwin, B., Shinozaki, K., Shiraishi, M., Shirron, P., Signorelli, G., Smecher, G., Spinella, F., Stever, S., Stompor, R., Sugiyama, S., Sullivan, R., Suzuki, A., Suzuki, J., Svalheim, T. L., Switzer, E., Takaku, R., Takakura, H., Takakura, S., Takase, Y., Takeda, Y., Tartari, A., Tavagnacco, D., Taylor, A., Taylor, E., Terao, Y., Thermeau, J., Thommesen, H., Thompson, K. L., Thorne, B., Toda, T., Tomasi, M., Tominaga, M., Trappe, N., Tristram, M., Tsuji, M., Tsujimoto, M., Tucker, C., Ullom, J., Vacher, L., Vermeulen, G., Vielva, P., Villa, F., Vissers, M., Vittorio, N., Wandelt, B., Wang, W., Watanuki, K., Wehus, I. K., Weller, J., Westbrook, B., Wilms, J., Winter, B., Wollack, E. J., Yamasaki, N. Y., Yoshida, T., Yumoto, J., Zacchei, A., Zannoni, M., and Zonca, A.

Published
2022
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12. Optical Characterization of OMT-Coupled TES Bolometers for LiteBIRD

Author

Hubmayr, J., Ade, P. A. R., Adler, A., Allys, E., Alonso, D., Arnold, K., Auguste, D., Aumont, J., Aurlien, R., Austermann, J. E., Azzoni, S., Baccigalupi, C., Banday, A. J., Banerji, R., Barreiro, R. B., Bartolo, N., Basak, S., Battistelli, E., Bautista, L., Beall, J. A., Beck, D., Beckman, S., Benabed, K., Bermejo-Ballesteros, J., Bersanelli, M., Bonis, J., Borrill, J., Bouchet, F., Boulanger, F., Bounissou, S., Brilenkov, M., Brown, M. L., Bucher, M., Calabrese, E., Calvo, M., Campeti, P., Carones, A., Casas, F. J., Catalano, A., Challinor, A., Chan, V., Cheung, K., Chinone, Y., Chiocchetta, C., Clark, S. E., Clermont, L., Clesse, S., Cliche, J., Columbro, F., Connors, J. A., Coppolecchia, A., Coulton, W., Cubas, J., Cukierman, A., Curtis, D., Cuttaia, F., D’Alessandro, G., Dachlythra, K., de Bernardis, P., de Haan, T., de la Hoz, E., De Petris, M., Della Torre, S., Daz Garca, J. J., Dickinson, C., Diego-Palazuelos, P., Dobbs, M., Dotani, T., Douillet, D., Doumayrou, E., Duband, L., Ducout, A., Duff, S. M., Duval, J. M., Ebisawa, K., Elleflot, T., Eriksen, H. K., Errard, J., Essinger-Hileman, T., Farrens, S., Finelli, F., Flauger, R., Fleury-Frenette, K., Franceschet, C., Fuskeland, U., Galli, L., Galli, S., Galloway, M., Ganga, K., Gao, J. R., Genova-Santos, R. T., Georges, M., Gerbino, M., Gervasi, M., Ghigna, T., Giardiello, S., Gjerlw, E., Gonzles, R. Gonzlez, Gradziel, M. L., Grain, J., Grandsire, L., Grupp, F., Gruppuso, A., Gudmundsson, J. E., Halverson, N. W., Hamilton, J., Hargrave, P., Hasebe, T., Hasegawa, M., Hattori, M., Hazumi, M., Henrot-Versill, S., Hensley, B., Herman, D., Herranz, D., Hilton, G. C., Hivon, E., Hlozek, R. A., Hoang, D., Hornsby, A. L., Hoshino, Y., Ichiki, K., Iida, T., Ikemoto, T., Imada, H., Ishimura, K., Ishino, H., Jaehnig, G., Jones, M., Kaga, T., Kashima, S., Katayama, N., Kato, A., Kawasaki, T., Keskitalo, R., Kintziger, C., Kisner, T., Kobayashi, Y., Kogiso, N., Kogut, A., Kohri, K., Komatsu, E., Komatsu, K., Konishi, K., Krachmalnicoff, N., Kreykenbohm, I., Kuo, C. L., Kushino, A., Lamagna, L., Lanen, J. V., Laquaniello, G., Lattanzi, M., Lee, A. T., Leloup, C., Levrier, F., Linder, E., Link, M. J., Lonappan, A. I., Louis, T., Luzzi, G., Macias-Perez, J., Maciaszek, T., Maffei, B., Maino, D., Maki, M., Mandelli, S., Maris, M., Marquet, B., Martnez-Gonzlez, E., Martire, F. A., Masi, S., Massa, M., Masuzawa, M., Matarrese, S., Matsuda, F. T., Matsumura, T., Mele, L., Mennella, A., Migliaccio, M., Minami, Y., Mitsuda, K., Moggi, A., Monelli, M., Monfardini, A., Montgomery, J., Montier, L., Morgante, G., Mot, B., Murata, Y., Murphy, J. A., Nagai, M., Nagano, Y., Nagasaki, T., Nagata, R., Nakamura, S., Nakano, R., Namikawa, T., Nati, F., Natoli, P., Nerval, S., Neto Godry Farias, N., Nishibori, T., Nishino, H., Noviello, F., O’Neil, G. C., O’Sullivan, C., Odagiri, K., Ochi, H., Ogawa, H., Ogawa, H., Oguri, S., Ohsaki, H., Ohta, I. S., Okada, N., Pagano, L., Paiella, A., Paoletti, D., Pascual Cisneros, G., Passerini, A., Patanchon, G., Pelgrim, V., Peloton, J., Pettorino, V., Piacentini, F., Piat, M., Piccirilli, G., Pinsard, F., Pisano, G., Plesseria, J., Polenta, G., Poletti, D., Prouv, T., Puglisi, G., Rambaud, D., Raum, C., Realini, S., Reinecke, M., Reintsema, C. D., Remazeilles, M., Ritacco, A., Rosier, P., Roudil, G., Rubino-Martin, J., Russell, M., Sakurai, H., Sakurai, Y., Sandri, M., Sasaki, M., Savini, G., Scott, D., Seibert, J., Sekimoto, Y., Sherwin, B., Shinozaki, K., Shiraishi, M., Shirron, P., Shitvov, A., Signorelli, G., Smecher, G., Spinella, F., Starck, J., Stever, S., Stompor, R., Sudiwala, R., Sugiyama, S., Sullivan, R., Suzuki, A., Suzuki, J., Suzuki, T., Svalheim, T. L., Switzer, E., Takaku, R., Takakura, H., Takakura, S., Takase, Y., Takeda, Y., Tartari, A., Tavagnacco, D., Taylor, A., Taylor, E., Terao, Y., Terenzi, L., Thermeau, J., Thommesen, H., Thompson, K. L., Thorne, B., Toda, T., Tomasi, M., Tominaga, M., Trappe, N., Tristram, M., Tsuji, M., Tsujimoto, M., Tucker, C., Ueki, R., Ullom, J. N., Umemori, K., Vacher, L., Van Lanen, J., Vermeulen, G., Vielva, P., Villa, F., Vissers, M. R., Vittorio, N., Wandelt, B., Wang, W., Wehus, I. K., Weller, J., Westbrook, B., Weymann-Despres, G., Wilms, J., Winter, B., Wollack, E. J., Yamasaki, N. Y., Yoshida, T., Yumoto, J., Watanuki, K., Zacchei, A., Zannoni, M., and Zonca, A.

Published
2022
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13. Real-world Effectiveness of Mepolizumab in the Treatment of Asthma in Japan: A Multicenter Retrospective Observational Study: J-Real-Mepo

Author

Nagase, H., primary, Kobayashi, K., additional, Suzukawa, M., additional, Masaki, K., additional, Miyata, Y., additional, Tsuji, M., additional, Terada, J., additional, Komatsuzaki, K., additional, Sugihara, N., additional, Kihara, T., additional, Ishikawa, N., additional, Koya, T., additional, Miyazaki, Y., additional, Hojo, M., additional, Tagaya, E., additional, Tanaka, A., additional, Harada, N., additional, Fukunaga, K., additional, and Gon, Y., additional

Published
2024
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14. Right Heart Reserve Function Assessed with Fluid Loading Test Predicts Late Right Heart Failure in Patients Undergoing Left Ventricular Assist Device Implantation

Author

Tsuji, M., primary, Kurihara, T., additional, Isotani, Y., additional, Bujo, C., additional, Ishida, J., additional, Amiya, E., additional, Hatano, M., additional, Kimura, M., additional, Shimada, S., additional, Ando, M., additional, Ono, M., additional, and Komuro, I., additional

Published
2024
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15. Linagliptin Inhibits Interleukin-6 Production Through Toll-Like Receptor 4 Complex and Lipopolysaccharide-Binding Protein Independent Pathway in vitro Model

Author

Saito H, Nakamura Y, Inagaki M, Yamadera S, Misawa H, Sato N, Oguchi T, Inagaki T, Tsuji Y, Tsuji M, Ohsawa I, Gotoh H, and Kiuchi Y

Subjects
lipopolysaccharide, u937 cells, fetal bovine serum, anti- toll-like receptor 4 antibody, interleukin-6, Pathology, RB1-214, Therapeutics. Pharmacology, RM1-950
Abstract

Hiroshi Saito,1 Yuya Nakamura,2,3 Masahiro Inagaki,2,4 Shiho Yamadera,5 Hideo Misawa,2,3 Naoki Sato,2,6 Tatsunori Oguchi,2 Takae Inagaki,7 Yuya Tsuji,2 Mayumi Tsuji,2 Isao Ohsawa,3 Hiromichi Gotoh,3 Yuji Kiuchi2 1JA Hiroshima Genneral Hospital, Hatsukaichi City, Hiroshima, Japan; 2Department of Pharmacology, Showa University School of Medicine, Shinagawa-ku, Tokyo, Japan; 3Saiyu Soka Hospital, Soka City, Saitama, Japan; 4Faculty of Arts and Sciences at Fujiyoshida, Showa University, Fujiyoshida City, Yamanashi, Japan; 5Department of Hospital Pharmaceutics, Showa University School of Pharmacy, Shinagawa-ku, Tokyo, Japan; 6Department of Research Center, Tanabe Pharmacy Inc., Chuo-ku, Tokyo, Japan; 7Graduate School of Nursing and Rehabilitation Science, Yokohama City, Kanagawa, JapanCorrespondence: Yuya Nakamura Email y.nakamura@med.showa-u.ac.jpPurpose: Lipopolysaccharides (LPS) induce inflammation by binding to the Toll-like receptor (TLR) 4 complex, including LPS-binding protein (LBP). The anti-inflammatory effects of linagliptin in LPS-induced inflammation in the TLR4-independent pathway have not been examined before. We examined the anti-inflammatory effects of linagliptin in the TLR4- and the LBP-independent pathway.Methods: U937 cells were cultured in the medium supplemented with 10% fetal bovine serum (FBS) and treated with 100 nM phorbol myristate acetate for 48 h. Cells were then left untreated or were treated with 10 μg/mL anti-TLR4 antibodies alone or in combination with linagliptin for 1 h in media supplemented with or without 10% FBS. The cells were divided into 5 groups: a) control cells (untreated) b) cells treated with LPS c) cells treated with 10 μg/mL anti-TLR4 antibodies d) cells treated with LPS and 10 μg/mL anti-TLR4 antibodies and e) cells treated with LPS, 10 μg/mL anti-TLR4 antibodies, and linagliptin. The LPS concentrations used were 50 pg/mL or 100 pg/mL for cells treated in the presence of 10% FBS and 100 pg/mL or 1 μg/mL for cells treated in the absence of FBS. Linagliptin concentrations of 1 nM, 10 nM, and 100 nM were used for treatment. The supernatants were analyzed for interleukin (IL)-6 production after 24 h of various treatments.Results: LPS increased IL-6 production compared to the untreated control cells, and anti-TLR4 antibody suppressed LPS-induced increased IL-6 levels. Linagliptin suppressed LPS-induced IL-6 production in a concentration-dependent manner in the presence of FBS. However, only 100 nM linagliptin could suppress LPS-induced IL-6 production in the absence of FBS.Conclusion: Concentration-dependent and -independent inflammatory suppression was observed following linagliptin treatment after LPS induction in an experimental model of TLR4 inhibition by anti-TLR4 antibodies. Our results showed that linagliptin may inhibit inflammation through multiple mechanisms centered around the TLR-4-mediated pathway.Keywords: lipopolysaccharide, U937 cells, fetal bovine serum, anti- toll-like receptor 4 antibody, interleukin-6

Published
2021

16. Sensitivity Modeling for LiteBIRD

Author

Hasebe, T, Ade, P, Adler, A, Allys, E, Alonso, D, Arnold, K, Auguste, D, Aumont, J, Aurlien, R, Austermann, J, Azzoni, S, Baccigalupi, C, Banday, A, Banerji, R, Barreiro, R, Bartolo, N, Basak, S, Battistelli, E, Bautista, L, Beall, J, Beck, D, Beckman, S, Benabed, K, Bermejo-Ballesteros, J, Bersanelli, M, Bonis, J, Borrill, J, Bouchet, F, Boulanger, F, Bounissou, S, Brilenkov, M, Brown, M, Bucher, M, Calabrese, E, Calvo, M, Campeti, P, Carones, A, Casas, F, Catalano, A, Challinor, A, Chan, V, Cheung, K, Chinone, Y, Cliche, J, Columbro, F, Coulton, W, Cubas, J, Cukierman, A, Curtis, D, D'Alessandro, G, Dachlythra, K, de Bernardis, P, de Haan, T, dela Hoz, E, De Petris, M, Torre, S, Dickinson, C, Diego-Palazuelos, P, Dobbs, M, Dotani, T, Douillet, D, Duband, L, Ducout, A, Duff, S, Duval, J, Ebisawa, K, Elleflot, T, Eriksen, H, Errard, J, Essinger-Hileman, T, Finelli, F, Flauger, R, Franceschet, C, Fuskeland, U, Galli, S, Galloway, M, Ganga, K, Gao, J, Genova-Santos, R, Gerbino, M, Gervasi, M, Ghigna, T, Giardiello, S, Gjerlow, E, Gradziel, M, Grain, J, Grandsire, L, Grupp, F, Gruppuso, A, Gudmundsson, J, Halverson, N, Hamilton, J, Hargrave, P, Hasegawa, M, Hattori, M, Hazumi, M, Henrot-Versille, S, Hergt, L, Herman, D, Herranz, D, Hill, C, Hilton, G, Hivon, E, Hlozek, R, Hoang, T, Hornsby, A, Hoshino, Y, Hubmayr, J, Ichiki, K, Iida, T, Imada, H, Ishimura, K, Ishino, H, Jaehnig, G, Jones, M, Kaga, T, Kashima, S, Katayama, N, Kato, A, Kawasaki, T, Keskitalo, R, Kisner, T, Kobayashi, Y, Kogiso, N, Kogut, A, Kohri, K, Komatsu, E, Komatsu, K, Konishi, K, Krachmalnicoff, N, Kreykenbohm, I, Kuo, C, Kushino, A, Lamagna, L, Lanen, J, Laquaniello, G, Lattanzi, M, Lee, A, Leloup, C, Levrier, F, Linder, E, Louis, T, Luzzi, G, Macias-Perez, J, Maciaszek, T, Maffei, B, Maino, D, Maki, M, Mandelli, S, Maris, M, Martinez-Gonzalez, E, Masi, S, Massa, M, Matarrese, S, Matsuda, F, Matsumura, T, Mele, L, Mennella, A, Migliaccio, M, Minami, Y, Mitsuda, K, Moggi, A, Monfardini, A, Montgomery, J, Montier, L, Morgante, G, Mot, B, Murata, Y, Murphy, J, Nagai, M, Nagano, Y, Nagasaki, T, Nagata, R, Nakamura, S, Nakano, R, Namikawa, T, Nati, F, Natoli, P, Nerval, S, Nishibori, T, Nishino, H, Noviello, F, O'Sullivan, C, Odagiri, K, Ogawa, H, Oguri, S, Ohsaki, H, Ohta, I, Okada, N, Pagano, L, Paiella, A, Paoletti, D, Passerini, A, Patanchon, G, Pelgrim, V, Peloton, J, Piacentini, F, Piat, M, Pisano, G, Polenta, G, Poletti, D, Prouve, T, Puglisi, G, Rambaud, D, Raum, C, Realini, S, Reinecke, M, Remazeilles, M, Ritacco, A, Roudil, G, Rubino-Martin, J, Russell, M, Sakurai, H, Sakurai, Y, Sandri, M, Sasaki, M, Savini, G, Scott, D, Seibert, J, Sekimoto, Y, Sherwin, B, Shinozaki, K, Shiraishi, M, Shirron, P, Signorelli, G, Smecher, G, Spinella, F, Stever, S, Stompor, R, Sugiyama, S, Sullivan, R, Suzuki, A, Suzuki, J, Svalheim, T, Switzer, E, Takaku, R, Takakura, H, Takakura, S, Takase, Y, Takeda, Y, Tartari, A, Tavagnacco, D, Taylor, A, Taylor, E, Terao, Y, Thermeau, J, Thommesen, H, Thompson, K, Thorne, B, Toda, T, Tomasi, M, Tominaga, M, Trappe, N, Tristram, M, Tsuji, M, Tsujimoto, M, Tucker, C, Ullom, J, Vacher, L, Vermeulen, G, Vielva, P, Villa, F, Vissers, M, Vittorio, N, Wandelt, B, Wang, W, Watanuki, K, Wehus, I, Weller, J, Westbrook, B, Wilms, J, Winter, B, Wollack, E, Yamasaki, N, Yoshida, T, Yumoto, J, Zacchei, A, Zannoni, M, Zonca, A, Hasebe T., Ade P. A. R., Adler A., Allys E., Alonso D., Arnold K., Auguste D., Aumont J., Aurlien R., Austermann J., Azzoni S., Baccigalupi C., Banday A. J., Banerji R., Barreiro R. B., Bartolo N., Basak S., Battistelli E., Bautista L., Beall J., Beck D., Beckman S., Benabed K., Bermejo-Ballesteros J., Bersanelli M., Bonis J., Borrill J., Bouchet F., Boulanger F., Bounissou S., Brilenkov M., Brown M. L., Bucher M., Calabrese E., Calvo M., Campeti P., Carones A., Casas F. J., Catalano A., Challinor A., Chan V., Cheung K., Chinone Y., Cliche J., Columbro F., Coulton W., Cubas J., Cukierman A., Curtis D., D'Alessandro G., Dachlythra K., de Bernardis P., de Haan T., dela Hoz E., De Petris M., Torre S. D., Dickinson C., Diego-Palazuelos P., Dobbs M., Dotani T., Douillet D., Duband L., Ducout A., Duff S., Duval J. M., Ebisawa K., Elleflot T., Eriksen H. K., Errard J., Essinger-Hileman T., Finelli F., Flauger R., Franceschet C., Fuskeland U., Galli S., Galloway M., Ganga K., Gao J. R., Genova-Santos R. T., Gerbino M., Gervasi M., Ghigna T., Giardiello S., Gjerlow E., Gradziel M. L., Grain J., Grandsire L., Grupp F., Gruppuso A., Gudmundsson J. E., Halverson N. W., Hamilton J., Hargrave P., Hasegawa M., Hattori M., Hazumi M., Henrot-Versille S., Hergt L. T., Herman D., Herranz D., Hill C. A., Hilton G., Hivon E., Hlozek R. A., Hoang T. D., Hornsby A. L., Hoshino Y., Hubmayr J., Ichiki K., Iida T., Imada H., Ishimura K., Ishino H., Jaehnig G., Jones M., Kaga T., Kashima S., Katayama N., Kato A., Kawasaki T., Keskitalo R., Kisner T., Kobayashi Y., Kogiso N., Kogut A., Kohri K., Komatsu E., Komatsu K., Konishi K., Krachmalnicoff N., Kreykenbohm I., Kuo C. L., Kushino A., Lamagna L., Lanen J. V., Laquaniello G., Lattanzi M., Lee A. T., Leloup C., Levrier F., Linder E., Louis T., Luzzi G., Macias-Perez J., Maciaszek T., Maffei B., Maino D., Maki M., Mandelli S., Maris M., Martinez-Gonzalez E., Masi S., Massa M., Matarrese S., Matsuda F. T., Matsumura T., Mele L., Mennella A., Migliaccio M., Minami Y., Mitsuda K., Moggi A., Monfardini A., Montgomery J., Montier L., Morgante G., Mot B., Murata Y., Murphy J. A., Nagai M., Nagano Y., Nagasaki T., Nagata R., Nakamura S., Nakano R., Namikawa T., Nati F., Natoli P., Nerval S., Nishibori T., Nishino H., Noviello F., O'Sullivan C., Odagiri K., Ogawa H., Oguri S., Ohsaki H., Ohta I. S., Okada N., Pagano L., Paiella A., Paoletti D., Passerini A., Patanchon G., Pelgrim V., Peloton J., Piacentini F., Piat M., Pisano G., Polenta G., Poletti D., Prouve T., Puglisi G., Rambaud D., Raum C., Realini S., Reinecke M., Remazeilles M., Ritacco A., Roudil G., Rubino-Martin J., Russell M., Sakurai H., Sakurai Y., Sandri M., Sasaki M., Savini G., Scott D., Seibert J., Sekimoto Y., Sherwin B., Shinozaki K., Shiraishi M., Shirron P., Signorelli G., Smecher G., Spinella F., Stever S., Stompor R., Sugiyama S., Sullivan R., Suzuki A., Suzuki J., Svalheim T. L., Switzer E., Takaku R., Takakura H., Takakura S., Takase Y., Takeda Y., Tartari A., Tavagnacco D., Taylor A., Taylor E., Terao Y., Thermeau J., Thommesen H., Thompson K. L., Thorne B., Toda T., Tomasi M., Tominaga M., Trappe N., Tristram M., Tsuji M., Tsujimoto M., Tucker C., Ullom J., Vacher L., Vermeulen G., Vielva P., Villa F., Vissers M., Vittorio N., Wandelt B., Wang W., Watanuki K., Wehus I. K., Weller J., Westbrook B., Wilms J., Winter B., Wollack E. J., Yamasaki N. Y., Yoshida T., Yumoto J., Zacchei A., Zannoni M., Zonca A., Hasebe, T, Ade, P, Adler, A, Allys, E, Alonso, D, Arnold, K, Auguste, D, Aumont, J, Aurlien, R, Austermann, J, Azzoni, S, Baccigalupi, C, Banday, A, Banerji, R, Barreiro, R, Bartolo, N, Basak, S, Battistelli, E, Bautista, L, Beall, J, Beck, D, Beckman, S, Benabed, K, Bermejo-Ballesteros, J, Bersanelli, M, Bonis, J, Borrill, J, Bouchet, F, Boulanger, F, Bounissou, S, Brilenkov, M, Brown, M, Bucher, M, Calabrese, E, Calvo, M, Campeti, P, Carones, A, Casas, F, Catalano, A, Challinor, A, Chan, V, Cheung, K, Chinone, Y, Cliche, J, Columbro, F, Coulton, W, Cubas, J, Cukierman, A, Curtis, D, D'Alessandro, G, Dachlythra, K, de Bernardis, P, de Haan, T, dela Hoz, E, De Petris, M, Torre, S, Dickinson, C, Diego-Palazuelos, P, Dobbs, M, Dotani, T, Douillet, D, Duband, L, Ducout, A, Duff, S, Duval, J, Ebisawa, K, Elleflot, T, Eriksen, H, Errard, J, Essinger-Hileman, T, Finelli, F, Flauger, R, Franceschet, C, Fuskeland, U, Galli, S, Galloway, M, Ganga, K, Gao, J, Genova-Santos, R, Gerbino, M, Gervasi, M, Ghigna, T, Giardiello, S, Gjerlow, E, Gradziel, M, Grain, J, Grandsire, L, Grupp, F, Gruppuso, A, Gudmundsson, J, Halverson, N, Hamilton, J, Hargrave, P, Hasegawa, M, Hattori, M, Hazumi, M, Henrot-Versille, S, Hergt, L, Herman, D, Herranz, D, Hill, C, Hilton, G, Hivon, E, Hlozek, R, Hoang, T, Hornsby, A, Hoshino, Y, Hubmayr, J, Ichiki, K, Iida, T, Imada, H, Ishimura, K, Ishino, H, Jaehnig, G, Jones, M, Kaga, T, Kashima, S, Katayama, N, Kato, A, Kawasaki, T, Keskitalo, R, Kisner, T, Kobayashi, Y, Kogiso, N, Kogut, A, Kohri, K, Komatsu, E, Komatsu, K, Konishi, K, Krachmalnicoff, N, Kreykenbohm, I, Kuo, C, Kushino, A, Lamagna, L, Lanen, J, Laquaniello, G, Lattanzi, M, Lee, A, Leloup, C, Levrier, F, Linder, E, Louis, T, Luzzi, G, Macias-Perez, J, Maciaszek, T, Maffei, B, Maino, D, Maki, M, Mandelli, S, Maris, M, Martinez-Gonzalez, E, Masi, S, Massa, M, Matarrese, S, Matsuda, F, Matsumura, T, Mele, L, Mennella, A, Migliaccio, M, Minami, Y, Mitsuda, K, Moggi, A, Monfardini, A, Montgomery, J, Montier, L, Morgante, G, Mot, B, Murata, Y, Murphy, J, Nagai, M, Nagano, Y, Nagasaki, T, Nagata, R, Nakamura, S, Nakano, R, Namikawa, T, Nati, F, Natoli, P, Nerval, S, Nishibori, T, Nishino, H, Noviello, F, O'Sullivan, C, Odagiri, K, Ogawa, H, Oguri, S, Ohsaki, H, Ohta, I, Okada, N, Pagano, L, Paiella, A, Paoletti, D, Passerini, A, Patanchon, G, Pelgrim, V, Peloton, J, Piacentini, F, Piat, M, Pisano, G, Polenta, G, Poletti, D, Prouve, T, Puglisi, G, Rambaud, D, Raum, C, Realini, S, Reinecke, M, Remazeilles, M, Ritacco, A, Roudil, G, Rubino-Martin, J, Russell, M, Sakurai, H, Sakurai, Y, Sandri, M, Sasaki, M, Savini, G, Scott, D, Seibert, J, Sekimoto, Y, Sherwin, B, Shinozaki, K, Shiraishi, M, Shirron, P, Signorelli, G, Smecher, G, Spinella, F, Stever, S, Stompor, R, Sugiyama, S, Sullivan, R, Suzuki, A, Suzuki, J, Svalheim, T, Switzer, E, Takaku, R, Takakura, H, Takakura, S, Takase, Y, Takeda, Y, Tartari, A, Tavagnacco, D, Taylor, A, Taylor, E, Terao, Y, Thermeau, J, Thommesen, H, Thompson, K, Thorne, B, Toda, T, Tomasi, M, Tominaga, M, Trappe, N, Tristram, M, Tsuji, M, Tsujimoto, M, Tucker, C, Ullom, J, Vacher, L, Vermeulen, G, Vielva, P, Villa, F, Vissers, M, Vittorio, N, Wandelt, B, Wang, W, Watanuki, K, Wehus, I, Weller, J, Westbrook, B, Wilms, J, Winter, B, Wollack, E, Yamasaki, N, Yoshida, T, Yumoto, J, Zacchei, A, Zannoni, M, Zonca, A, Hasebe T., Ade P. A. R., Adler A., Allys E., Alonso D., Arnold K., Auguste D., Aumont J., Aurlien R., Austermann J., Azzoni S., Baccigalupi C., Banday A. J., Banerji R., Barreiro R. B., Bartolo N., Basak S., Battistelli E., Bautista L., Beall J., Beck D., Beckman S., Benabed K., Bermejo-Ballesteros J., Bersanelli M., Bonis J., Borrill J., Bouchet F., Boulanger F., Bounissou S., Brilenkov M., Brown M. L., Bucher M., Calabrese E., Calvo M., Campeti P., Carones A., Casas F. J., Catalano A., Challinor A., Chan V., Cheung K., Chinone Y., Cliche J., Columbro F., Coulton W., Cubas J., Cukierman A., Curtis D., D'Alessandro G., Dachlythra K., de Bernardis P., de Haan T., dela Hoz E., De Petris M., Torre S. D., Dickinson C., Diego-Palazuelos P., Dobbs M., Dotani T., Douillet D., Duband L., Ducout A., Duff S., Duval J. M., Ebisawa K., Elleflot T., Eriksen H. K., Errard J., Essinger-Hileman T., Finelli F., Flauger R., Franceschet C., Fuskeland U., Galli S., Galloway M., Ganga K., Gao J. R., Genova-Santos R. T., Gerbino M., Gervasi M., Ghigna T., Giardiello S., Gjerlow E., Gradziel M. L., Grain J., Grandsire L., Grupp F., Gruppuso A., Gudmundsson J. E., Halverson N. W., Hamilton J., Hargrave P., Hasegawa M., Hattori M., Hazumi M., Henrot-Versille S., Hergt L. T., Herman D., Herranz D., Hill C. A., Hilton G., Hivon E., Hlozek R. A., Hoang T. D., Hornsby A. L., Hoshino Y., Hubmayr J., Ichiki K., Iida T., Imada H., Ishimura K., Ishino H., Jaehnig G., Jones M., Kaga T., Kashima S., Katayama N., Kato A., Kawasaki T., Keskitalo R., Kisner T., Kobayashi Y., Kogiso N., Kogut A., Kohri K., Komatsu E., Komatsu K., Konishi K., Krachmalnicoff N., Kreykenbohm I., Kuo C. L., Kushino A., Lamagna L., Lanen J. V., Laquaniello G., Lattanzi M., Lee A. T., Leloup C., Levrier F., Linder E., Louis T., Luzzi G., Macias-Perez J., Maciaszek T., Maffei B., Maino D., Maki M., Mandelli S., Maris M., Martinez-Gonzalez E., Masi S., Massa M., Matarrese S., Matsuda F. T., Matsumura T., Mele L., Mennella A., Migliaccio M., Minami Y., Mitsuda K., Moggi A., Monfardini A., Montgomery J., Montier L., Morgante G., Mot B., Murata Y., Murphy J. A., Nagai M., Nagano Y., Nagasaki T., Nagata R., Nakamura S., Nakano R., Namikawa T., Nati F., Natoli P., Nerval S., Nishibori T., Nishino H., Noviello F., O'Sullivan C., Odagiri K., Ogawa H., Oguri S., Ohsaki H., Ohta I. S., Okada N., Pagano L., Paiella A., Paoletti D., Passerini A., Patanchon G., Pelgrim V., Peloton J., Piacentini F., Piat M., Pisano G., Polenta G., Poletti D., Prouve T., Puglisi G., Rambaud D., Raum C., Realini S., Reinecke M., Remazeilles M., Ritacco A., Roudil G., Rubino-Martin J., Russell M., Sakurai H., Sakurai Y., Sandri M., Sasaki M., Savini G., Scott D., Seibert J., Sekimoto Y., Sherwin B., Shinozaki K., Shiraishi M., Shirron P., Signorelli G., Smecher G., Spinella F., Stever S., Stompor R., Sugiyama S., Sullivan R., Suzuki A., Suzuki J., Svalheim T. L., Switzer E., Takaku R., Takakura H., Takakura S., Takase Y., Takeda Y., Tartari A., Tavagnacco D., Taylor A., Taylor E., Terao Y., Thermeau J., Thommesen H., Thompson K. L., Thorne B., Toda T., Tomasi M., Tominaga M., Trappe N., Tristram M., Tsuji M., Tsujimoto M., Tucker C., Ullom J., Vacher L., Vermeulen G., Vielva P., Villa F., Vissers M., Vittorio N., Wandelt B., Wang W., Watanuki K., Wehus I. K., Weller J., Westbrook B., Wilms J., Winter B., Wollack E. J., Yamasaki N. Y., Yoshida T., Yumoto J., Zacchei A., Zannoni M., and Zonca A.

Abstract

LiteBIRD is a future satellite mission designed to observe the polarization of the cosmic microwave background radiation in order to probe the inflationary universe. LiteBIRD is set to observe the sky using three telescopes with transition-edge sensor bolometers. In this work we estimated the LiteBIRD instrumental sensitivity using its current design. We estimated the detector noise due to the optical loadings using physical optics and ray-tracing simulations. The noise terms associated with thermal carrier and readout noise were modeled in the detector noise calculation. We calculated the observational sensitivities over fifteen bands designed for the LiteBIRD telescopes using assumed observation time efficiency.

Published
2023

17. An MDL algorithm for detecting more sources than sensors using outer-products of array output

Author

Cheng, Q, Pal, P, Tsuji, M, and Hua, Y

Subjects
Array output, detection, MDL, outer-product, redundancy array, Networking & Telecommunications
Abstract

In this paper, we propose an algorithm for detecting the number $M$ of Gaussian sources received by an array of a number $N$ ($N< M$ ) of sensors. This algorithm is based on the minimum description length (MDL) principle using the outer-products of the array output. We show that as long as the covariance matrix of the array output has the full rank $N$, the covariance matrix of a vectorized outer-product of the array output has the full rank $N$-squared, which meets a validity condition of the MDL algorithm. We show by simulation that the MDL algorithm can perform substantially better than some relevant algorithms. A necessary identifiability condition is also obtained, for uncorrelated sources.

Published
2014

18. Linagliptin Inhibits Lipopolysaccharide-Induced Inflammation Concentration-Dependently And -Independently

Author

Sato N, Nakamura Y, Yamadera S, Inagaki M, Kenmotsu S, Saito H, Oguchi T, Tsuji M, Chokki H, Ohsawa I, Gotoh H, Iwai S, and Kiuchi Y

Subjects
linagliptin, lipopolysaccharide, lipopolysaccharide-binding protein, interleukin-6, intranuclear subunit of nuclear factor-κB/p65, intracellular reactive oxygen species, Pathology, RB1-214, Therapeutics. Pharmacology, RM1-950
Abstract

Naoki Sato,1,2 Yuya Nakamura,1,3 Shiho Yamadera,4 Masahiro Inagaki,1,5 Sachiyo Kenmotsu,5 Hiroshi Saito,4,6 Tatsunori Oguchi,1 Mayumi Tsuji,1 Hirokazu Chokki,1 Isao Ohsawa,3 Hiromichi Gotoh,3 Shinichi Iwai,6 Yuji Kiuchi1 1Department of Pharmacology, Showa University School of Medicine, Shinagawa-ku, Tokyo, Japan; 2Department of Research Center, Tanabe Pharmacy Inc., Tokyo, Japan; 3Department of Nephrology, Saiyu Soka Hospital, Soka City, Saitama-ken, Japan; 4Department of Hospital Pharmaceutics, Showa University School of Pharmacy, Shinagawa-ku, Tokyo, Japan; 5Fuculty of Arts and Sciences at Fujiyoshida, Showa University, Fujiyoshida City, Yamanashi-ken, Japan; 6Department of Healthcare and Regulatory Sciences, Showa University School of Pharmacy, Shinagawa-ku, Tokyo, JapanCorrespondence: Yuya NakamuraDepartment of Pharmacology, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, JapanTel +81-3-3784-8125Fax +81-3-3787-4790Email y.nakamura@med.showa-u.ac.jpPurpose: Dipeptidyl peptidase-4 inhibitors, including linagliptin, prevent inflammation. However, the in vitro effects of linagliptin are unclear. Moreover, although linagliptin inhibits lipopolysaccharide (LPS)-induced inflammation, the anti-inflammatory effects of linagliptin in this context are not concentration-dependent. In the absence of LPS-binding protein (LBP), the pro-inflammatory effects of LPS involve pathways other than the Toll-like receptor (TLR) 4 pathway. Here, we aimed to determine the anti-inflammatory mechanisms of linagliptin in an experimental model in which LBP was added to the medium.Methods: Human U937 monocytes were cultured at 1 × 106 cells/mL in Roswell Park Memorial Institute medium and differentiated into macrophages using phorbol myristate acetate. All processes were carried out in medium containing 10% fetal bovine serum (FBS). After 48 hrs of culture, we replaced the medium and pretreated the cells with 100, 250, 500, or 2500 nM linagliptin for 1 hr. We exchanged the medium again, and the cells were treated with 1 ng/mL LPS with or without 100, 250, 500, or 2500 nM linagliptin. Interleukin (IL)-6 and LBP in the supernatant, nuclear factor (NF)-κB/p65 in the nucleus, and reactive oxygen species (ROS) in the cells, as important markers of the mechanism of inflammation induction by LPS, were measured using enzyme-linked immunosorbent assay kits.Results: Linagliptin significantly prevented LPS-stimulated IL-6 production and intranuclear NF-κB/p65 levels in a concentration-dependent manner. LPS-induced intracellular ROS levels were significantly decreased by linagliptin at all concentrations. LBP levels were markedly higher in FBS-containing medium than in medium without FBS. However, LBP levels did not change following administration of linagliptin and/or LPS.Conclusion: Concentration-dependent and -independent inflammatory suppression was observed following linagliptin treatment in the context of LPS-induced pro-inflammatory responses. Thus, our findings suggested that linagliptin induced two different mechanisms to repress inflammation, i.e., TLR4-dependent and -independent mechanisms.Keywords: linagliptin, lipopolysaccharide-binding protein, interleukin-6, intranuclear subunit of nuclear factor-κB/p65, reactive oxygen species

Published
2019

21. Intracranial Subdural Hematoma after Lumbar Spine Surgery: A Case Report

Author

Zakaria AF and Tsuji M

Subjects
subdural hematoma, intracranial hypotension, csf leaks, lumbar surgery, Orthopedic surgery, RD701-811
Abstract

Intracranial subdural hematoma following lumbar surgery is a devastating but rare complication. It has been implicated due to intracranial hypotension secondary to persistent cerebrospinal fluid leakage. The resultant drop in intracranial pressure presumably causes traction and tearing of venous structures. Patients typically present with postural headaches. However, other symptoms of subdural hematoma, intracranial hypotension and cerebrospinal fluid leak must also be cautioned.

Published
2019
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22. Tensor-to-scalar ratio forecasts for extended LiteBIRD frequency configurations

Author

Fuskeland, U., primary, Aumont, J., additional, Aurlien, R., additional, Baccigalupi, C., additional, Banday, A. J., additional, Eriksen, H. K., additional, Errard, J., additional, Génova-Santos, R. T., additional, Hasebe, T., additional, Hubmayr, J., additional, Imada, H., additional, Krachmalnicoff, N., additional, Lamagna, L., additional, Pisano, G., additional, Poletti, D., additional, Remazeilles, M., additional, Thompson, K. L., additional, Vacher, L., additional, Wehus, I. K., additional, Azzoni, S., additional, Ballardini, M., additional, Barreiro, R. B., additional, Bartolo, N., additional, Basyrov, A., additional, Beck, D., additional, Bersanelli, M., additional, Bortolami, M., additional, Brilenkov, M., additional, Calabrese, E., additional, Carones, A., additional, Casas, F. J., additional, Cheung, K., additional, Chluba, J., additional, Clark, S. E., additional, Clermont, L., additional, Columbro, F., additional, Coppolecchia, A., additional, D’Alessandro, G., additional, de Bernardis, P., additional, de Haan, T., additional, de la Hoz, E., additional, De Petris, M., additional, Della Torre, S., additional, Diego-Palazuelos, P., additional, Finelli, F., additional, Franceschet, C., additional, Galloni, G., additional, Galloway, M., additional, Gerbino, M., additional, Gervasi, M., additional, Ghigna, T., additional, Giardiello, S., additional, Gjerløw, E., additional, Gruppuso, A., additional, Hargrave, P., additional, Hattori, M., additional, Hazumi, M., additional, Hergt, L. T., additional, Herman, D., additional, Herranz, D., additional, Hivon, E., additional, Hoang, T. D., additional, Kohri, K., additional, Lattanzi, M., additional, Lee, A. T., additional, Leloup, C., additional, Levrier, F., additional, Lonappan, A. I., additional, Luzzi, G., additional, Maffei, B., additional, Martínez-González, E., additional, Masi, S., additional, Matarrese, S., additional, Matsumura, T., additional, Migliaccio, M., additional, Montier, L., additional, Morgante, G., additional, Mot, B., additional, Mousset, L., additional, Nagata, R., additional, Namikawa, T., additional, Nati, F., additional, Natoli, P., additional, Nerval, S., additional, Novelli, A., additional, Pagano, L., additional, Paiella, A., additional, Paoletti, D., additional, Pascual-Cisneros, G., additional, Patanchon, G., additional, Pelgrims, V., additional, Piacentini, F., additional, Piccirilli, G., additional, Polenta, G., additional, Puglisi, G., additional, Raffuzzi, N., additional, Ritacco, A., additional, Rubino-Martin, J. A., additional, Savini, G., additional, Scott, D., additional, Sekimoto, Y., additional, Shiraishi, M., additional, Signorelli, G., additional, Stever, S. L., additional, Stutzer, N., additional, Sullivan, R. M., additional, Takakura, H., additional, Terenzi, L., additional, Thommesen, H., additional, Tristram, M., additional, Tsuji, M., additional, Vielva, P., additional, Weller, J., additional, Westbrook, B., additional, Weymann-Despres, G., additional, Wollack, E. J., additional, and Zannoni, M., additional

Published
2023
Full Text
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23. Optical Characterization of OMT-Coupled TES Bolometers for LiteBIRD

Author

Hubmayr, J, Ade, P, Adler, A, Allys, E, Alonso, D, Arnold, K, Auguste, D, Aumont, J, Aurlien, R, Austermann, J, Azzoni, S, Baccigalupi, C, Banday, A, Banerji, R, Barreiro, R, Bartolo, N, Basak, S, Battistelli, E, Bautista, L, Beall, J, Beck, D, Beckman, S, Benabed, K, Bermejo-Ballesteros, J, Bersanelli, M, Bonis, J, Borrill, J, Bouchet, F, Boulanger, F, Bounissou, S, Brilenkov, M, Brown, M, Bucher, M, Calabrese, E, Calvo, M, Campeti, P, Carones, A, Casas, F, Catalano, A, Challinor, A, Chan, V, Cheung, K, Chinone, Y, Chiocchetta, C, Clark, S, Clermont, L, Clesse, S, Cliche, J, Columbro, F, Connors, J, Coppolecchia, A, Coulton, W, Cubas, J, Cukierman, A, Curtis, D, Cuttaia, F, D’Alessandro, G, Dachlythra, K, de Bernardis, P, de Haan, T, de la Hoz, E, De Petris, M, Della Torre, S, Daz Garca, J, Dickinson, C, Diego-Palazuelos, P, Dobbs, M, Dotani, T, Douillet, D, Doumayrou, E, Duband, L, Ducout, A, Duff, S, Duval, J, Ebisawa, K, Elleflot, T, Eriksen, H, Errard, J, Essinger-Hileman, T, Farrens, S, Finelli, F, Flauger, R, Fleury-Frenette, K, Franceschet, C, Fuskeland, U, Galli, L, Galli, S, Galloway, M, Ganga, K, Gao, J, Genova-Santos, R, Georges, M, Gerbino, M, Gervasi, M, Ghigna, T, Giardiello, S, Gjerlw, E, Gonzles, R, Gradziel, M, Grain, J, Grandsire, L, Grupp, F, Gruppuso, A, Gudmundsson, J, Halverson, N, Hamilton, J, Hargrave, P, Hasebe, T, Hasegawa, M, Hattori, M, Hazumi, M, Henrot-Versill, S, Hensley, B, Herman, D, Herranz, D, Hilton, G, Hivon, E, Hlozek, R, Hoang, D, Hornsby, A, Hoshino, Y, Ichiki, K, Iida, T, Ikemoto, T, Imada, H, Ishimura, K, Ishino, H, Jaehnig, G, Jones, M, Kaga, T, Kashima, S, Katayama, N, Kato, A, Kawasaki, T, Keskitalo, R, Kintziger, C, Kisner, T, Kobayashi, Y, Kogiso, N, Kogut, A, Kohri, K, Komatsu, E, Komatsu, K, Konishi, K, Krachmalnicoff, N, Kreykenbohm, I, Kuo, C, Kushino, A, Lamagna, L, Lanen, J, Laquaniello, G, Lattanzi, M, Lee, A, Leloup, C, Levrier, F, Linder, E, Link, M, Lonappan, A, Louis, T, Luzzi, G, Macias-Perez, J, Maciaszek, T, Maffei, B, Maino, D, Maki, M, Mandelli, S, Maris, M, Marquet, B, Martnez-Gonzlez, E, Martire, F, Masi, S, Massa, M, Masuzawa, M, Matarrese, S, Matsuda, F, Matsumura, T, Mele, L, Mennella, A, Migliaccio, M, Minami, Y, Mitsuda, K, Moggi, A, Monelli, M, Monfardini, A, Montgomery, J, Montier, L, Morgante, G, Mot, B, Murata, Y, Murphy, J, Nagai, M, Nagano, Y, Nagasaki, T, Nagata, R, Nakamura, S, Nakano, R, Namikawa, T, Nati, F, Natoli, P, Nerval, S, Neto Godry Farias, N, Nishibori, T, Nishino, H, Noviello, F, O’Neil, G, O’Sullivan, C, Odagiri, K, Ochi, H, Ogawa, H, Oguri, S, Ohsaki, H, Ohta, I, Okada, N, Pagano, L, Paiella, A, Paoletti, D, Pascual Cisneros, G, Passerini, A, Patanchon, G, Pelgrim, V, Peloton, J, Pettorino, V, Piacentini, F, Piat, M, Piccirilli, G, Pinsard, F, Pisano, G, Plesseria, J, Polenta, G, Poletti, D, Prouv, T, Puglisi, G, Rambaud, D, Raum, C, Realini, S, Reinecke, M, Reintsema, C, Remazeilles, M, Ritacco, A, Rosier, P, Roudil, G, Rubino-Martin, J, Russell, M, Sakurai, H, Sakurai, Y, Sandri, M, Sasaki, M, Savini, G, Scott, D, Seibert, J, Sekimoto, Y, Sherwin, B, Shinozaki, K, Shiraishi, M, Shirron, P, Shitvov, A, Signorelli, G, Smecher, G, Spinella, F, Starck, J, Stever, S, Stompor, R, Sudiwala, R, Sugiyama, S, Sullivan, R, Suzuki, A, Suzuki, J, Suzuki, T, Svalheim, T, Switzer, E, Takaku, R, Takakura, H, Takakura, S, Takase, Y, Takeda, Y, Tartari, A, Tavagnacco, D, Taylor, A, Taylor, E, Terao, Y, Terenzi, L, Thermeau, J, Thommesen, H, Thompson, K, Thorne, B, Toda, T, Tomasi, M, Tominaga, M, Trappe, N, Tristram, M, Tsuji, M, Tsujimoto, M, Tucker, C, Ueki, R, Ullom, J, Umemori, K, Vacher, L, Van Lanen, J, Vermeulen, G, Vielva, P, Villa, F, Vissers, M, Vittorio, N, Wandelt, B, Wang, W, Wehus, I, Weller, J, Westbrook, B, Weymann-Despres, G, Wilms, J, Winter, B, Wollack, E, Yamasaki, N, Yoshida, T, Yumoto, J, Watanuki, K, Zacchei, A, Zannoni, M, Zonca, A, Hubmayr, J., Ade, P. A. R., Adler, A., Allys, E., Alonso, D., Arnold, K., Auguste, D., Aumont, J., Aurlien, R., Austermann, J. E., Azzoni, S., Baccigalupi, C., Banday, A. J., Banerji, R., Barreiro, R. B., Bartolo, N., Basak, S., Battistelli, E., Bautista, L., Beall, J. A., Beck, D., Beckman, S., Benabed, K., Bermejo-Ballesteros, J., Bersanelli, M., Bonis, J., Borrill, J., Bouchet, F., Boulanger, F., Bounissou, S., Brilenkov, M., Brown, M. L., Bucher, M., Calabrese, E., Calvo, M., Campeti, P., Carones, A., Casas, F. J., Catalano, A., Challinor, A., Chan, V., Cheung, K., Chinone, Y., Chiocchetta, C., Clark, S. E., Clermont, L., Clesse, S., Cliche, J., Columbro, F., Connors, J. A., Coppolecchia, A., Coulton, W., Cubas, J., Cukierman, A., Curtis, D., Cuttaia, F., D’Alessandro, G., Dachlythra, K., de Bernardis, P., de Haan, T., de la Hoz, E., De Petris, M., Della Torre, S., Daz Garca, J. J., Dickinson, C., Diego-Palazuelos, P., Dobbs, M., Dotani, T., Douillet, D., Doumayrou, E., Duband, L., Ducout, A., Duff, S. M., Duval, J. M., Ebisawa, K., Elleflot, T., Eriksen, H. K., Errard, J., Essinger-Hileman, T., Farrens, S., Finelli, F., Flauger, R., Fleury-Frenette, K., Franceschet, C., Fuskeland, U., Galli, L., Galli, S., Galloway, M., Ganga, K., Gao, J. R., Genova-Santos, R. T., Georges, M., Gerbino, M., Gervasi, M., Ghigna, T., Giardiello, S., Gjerlw, E., Gonzles, R. Gonzlez, Gradziel, M. L., Grain, J., Grandsire, L., Grupp, F., Gruppuso, A., Gudmundsson, J. E., Halverson, N. W., Hamilton, J., Hargrave, P., Hasebe, T., Hasegawa, M., Hattori, M., Hazumi, M., Henrot-Versill, S., Hensley, B., Herman, D., Herranz, D., Hilton, G. C., Hivon, E., Hlozek, R. A., Hoang, D., Hornsby, A. L., Hoshino, Y., Ichiki, K., Iida, T., Ikemoto, T., Imada, H., Ishimura, K., Ishino, H., Jaehnig, G., Jones, M., Kaga, T., Kashima, S., Katayama, N., Kato, A., Kawasaki, T., Keskitalo, R., Kintziger, C., Kisner, T., Kobayashi, Y., Kogiso, N., Kogut, A., Kohri, K., Komatsu, E., Komatsu, K., Konishi, K., Krachmalnicoff, N., Kreykenbohm, I., Kuo, C. L., Kushino, A., Lamagna, L., Lanen, J. V., Laquaniello, G., Lattanzi, M., Lee, A. T., Leloup, C., Levrier, F., Linder, E., Link, M. J., Lonappan, A. I., Louis, T., Luzzi, G., Macias-Perez, J., Maciaszek, T., Maffei, B., Maino, D., Maki, M., Mandelli, S., Maris, M., Marquet, B., Martnez-Gonzlez, E., Martire, F. A., Masi, S., Massa, M., Masuzawa, M., Matarrese, S., Matsuda, F. T., Matsumura, T., Mele, L., Mennella, A., Migliaccio, M., Minami, Y., Mitsuda, K., Moggi, A., Monelli, M., Monfardini, A., Montgomery, J., Montier, L., Morgante, G., Mot, B., Murata, Y., Murphy, J. A., Nagai, M., Nagano, Y., Nagasaki, T., Nagata, R., Nakamura, S., Nakano, R., Namikawa, T., Nati, F., Natoli, P., Nerval, S., Neto Godry Farias, N., Nishibori, T., Nishino, H., Noviello, F., O’Neil, G. C., O’Sullivan, C., Odagiri, K., Ochi, H., Ogawa, H., Oguri, S., Ohsaki, H., Ohta, I. S., Okada, N., Pagano, L., Paiella, A., Paoletti, D., Pascual Cisneros, G., Passerini, A., Patanchon, G., Pelgrim, V., Peloton, J., Pettorino, V., Piacentini, F., Piat, M., Piccirilli, G., Pinsard, F., Pisano, G., Plesseria, J., Polenta, G., Poletti, D., Prouv, T., Puglisi, G., Rambaud, D., Raum, C., Realini, S., Reinecke, M., Reintsema, C. D., Remazeilles, M., Ritacco, A., Rosier, P., Roudil, G., Rubino-Martin, J., Russell, M., Sakurai, H., Sakurai, Y., Sandri, M., Sasaki, M., Savini, G., Scott, D., Seibert, J., Sekimoto, Y., Sherwin, B., Shinozaki, K., Shiraishi, M., Shirron, P., Shitvov, A., Signorelli, G., Smecher, G., Spinella, F., Starck, J., Stever, S., Stompor, R., Sudiwala, R., Sugiyama, S., Sullivan, R., Suzuki, A., Suzuki, J., Suzuki, T., Svalheim, T. L., Switzer, E., Takaku, R., Takakura, H., Takakura, S., Takase, Y., Takeda, Y., Tartari, A., Tavagnacco, D., Taylor, A., Taylor, E., Terao, Y., Terenzi, L., Thermeau, J., Thommesen, H., Thompson, K. L., Thorne, B., Toda, T., Tomasi, M., Tominaga, M., Trappe, N., Tristram, M., Tsuji, M., Tsujimoto, M., Tucker, C., Ueki, R., Ullom, J. N., Umemori, K., Vacher, L., Van Lanen, J., Vermeulen, G., Vielva, P., Villa, F., Vissers, M. R., Vittorio, N., Wandelt, B., Wang, W., Wehus, I. K., Weller, J., Westbrook, B., Weymann-Despres, G., Wilms, J., Winter, B., Wollack, E. J., Yamasaki, N. Y., Yoshida, T., Yumoto, J., Watanuki, K., Zacchei, A., Zannoni, M., Zonca, A., Hubmayr, J, Ade, P, Adler, A, Allys, E, Alonso, D, Arnold, K, Auguste, D, Aumont, J, Aurlien, R, Austermann, J, Azzoni, S, Baccigalupi, C, Banday, A, Banerji, R, Barreiro, R, Bartolo, N, Basak, S, Battistelli, E, Bautista, L, Beall, J, Beck, D, Beckman, S, Benabed, K, Bermejo-Ballesteros, J, Bersanelli, M, Bonis, J, Borrill, J, Bouchet, F, Boulanger, F, Bounissou, S, Brilenkov, M, Brown, M, Bucher, M, Calabrese, E, Calvo, M, Campeti, P, Carones, A, Casas, F, Catalano, A, Challinor, A, Chan, V, Cheung, K, Chinone, Y, Chiocchetta, C, Clark, S, Clermont, L, Clesse, S, Cliche, J, Columbro, F, Connors, J, Coppolecchia, A, Coulton, W, Cubas, J, Cukierman, A, Curtis, D, Cuttaia, F, D’Alessandro, G, Dachlythra, K, de Bernardis, P, de Haan, T, de la Hoz, E, De Petris, M, Della Torre, S, Daz Garca, J, Dickinson, C, Diego-Palazuelos, P, Dobbs, M, Dotani, T, Douillet, D, Doumayrou, E, Duband, L, Ducout, A, Duff, S, Duval, J, Ebisawa, K, Elleflot, T, Eriksen, H, Errard, J, Essinger-Hileman, T, Farrens, S, Finelli, F, Flauger, R, Fleury-Frenette, K, Franceschet, C, Fuskeland, U, Galli, L, Galli, S, Galloway, M, Ganga, K, Gao, J, Genova-Santos, R, Georges, M, Gerbino, M, Gervasi, M, Ghigna, T, Giardiello, S, Gjerlw, E, Gonzles, R, Gradziel, M, Grain, J, Grandsire, L, Grupp, F, Gruppuso, A, Gudmundsson, J, Halverson, N, Hamilton, J, Hargrave, P, Hasebe, T, Hasegawa, M, Hattori, M, Hazumi, M, Henrot-Versill, S, Hensley, B, Herman, D, Herranz, D, Hilton, G, Hivon, E, Hlozek, R, Hoang, D, Hornsby, A, Hoshino, Y, Ichiki, K, Iida, T, Ikemoto, T, Imada, H, Ishimura, K, Ishino, H, Jaehnig, G, Jones, M, Kaga, T, Kashima, S, Katayama, N, Kato, A, Kawasaki, T, Keskitalo, R, Kintziger, C, Kisner, T, Kobayashi, Y, Kogiso, N, Kogut, A, Kohri, K, Komatsu, E, Komatsu, K, Konishi, K, Krachmalnicoff, N, Kreykenbohm, I, Kuo, C, Kushino, A, Lamagna, L, Lanen, J, Laquaniello, G, Lattanzi, M, Lee, A, Leloup, C, Levrier, F, Linder, E, Link, M, Lonappan, A, Louis, T, Luzzi, G, Macias-Perez, J, Maciaszek, T, Maffei, B, Maino, D, Maki, M, Mandelli, S, Maris, M, Marquet, B, Martnez-Gonzlez, E, Martire, F, Masi, S, Massa, M, Masuzawa, M, Matarrese, S, Matsuda, F, Matsumura, T, Mele, L, Mennella, A, Migliaccio, M, Minami, Y, Mitsuda, K, Moggi, A, Monelli, M, Monfardini, A, Montgomery, J, Montier, L, Morgante, G, Mot, B, Murata, Y, Murphy, J, Nagai, M, Nagano, Y, Nagasaki, T, Nagata, R, Nakamura, S, Nakano, R, Namikawa, T, Nati, F, Natoli, P, Nerval, S, Neto Godry Farias, N, Nishibori, T, Nishino, H, Noviello, F, O’Neil, G, O’Sullivan, C, Odagiri, K, Ochi, H, Ogawa, H, Oguri, S, Ohsaki, H, Ohta, I, Okada, N, Pagano, L, Paiella, A, Paoletti, D, Pascual Cisneros, G, Passerini, A, Patanchon, G, Pelgrim, V, Peloton, J, Pettorino, V, Piacentini, F, Piat, M, Piccirilli, G, Pinsard, F, Pisano, G, Plesseria, J, Polenta, G, Poletti, D, Prouv, T, Puglisi, G, Rambaud, D, Raum, C, Realini, S, Reinecke, M, Reintsema, C, Remazeilles, M, Ritacco, A, Rosier, P, Roudil, G, Rubino-Martin, J, Russell, M, Sakurai, H, Sakurai, Y, Sandri, M, Sasaki, M, Savini, G, Scott, D, Seibert, J, Sekimoto, Y, Sherwin, B, Shinozaki, K, Shiraishi, M, Shirron, P, Shitvov, A, Signorelli, G, Smecher, G, Spinella, F, Starck, J, Stever, S, Stompor, R, Sudiwala, R, Sugiyama, S, Sullivan, R, Suzuki, A, Suzuki, J, Suzuki, T, Svalheim, T, Switzer, E, Takaku, R, Takakura, H, Takakura, S, Takase, Y, Takeda, Y, Tartari, A, Tavagnacco, D, Taylor, A, Taylor, E, Terao, Y, Terenzi, L, Thermeau, J, Thommesen, H, Thompson, K, Thorne, B, Toda, T, Tomasi, M, Tominaga, M, Trappe, N, Tristram, M, Tsuji, M, Tsujimoto, M, Tucker, C, Ueki, R, Ullom, J, Umemori, K, Vacher, L, Van Lanen, J, Vermeulen, G, Vielva, P, Villa, F, Vissers, M, Vittorio, N, Wandelt, B, Wang, W, Wehus, I, Weller, J, Westbrook, B, Weymann-Despres, G, Wilms, J, Winter, B, Wollack, E, Yamasaki, N, Yoshida, T, Yumoto, J, Watanuki, K, Zacchei, A, Zannoni, M, Zonca, A, Hubmayr, J., Ade, P. A. R., Adler, A., Allys, E., Alonso, D., Arnold, K., Auguste, D., Aumont, J., Aurlien, R., Austermann, J. E., Azzoni, S., Baccigalupi, C., Banday, A. J., Banerji, R., Barreiro, R. B., Bartolo, N., Basak, S., Battistelli, E., Bautista, L., Beall, J. A., Beck, D., Beckman, S., Benabed, K., Bermejo-Ballesteros, J., Bersanelli, M., Bonis, J., Borrill, J., Bouchet, F., Boulanger, F., Bounissou, S., Brilenkov, M., Brown, M. L., Bucher, M., Calabrese, E., Calvo, M., Campeti, P., Carones, A., Casas, F. J., Catalano, A., Challinor, A., Chan, V., Cheung, K., Chinone, Y., Chiocchetta, C., Clark, S. E., Clermont, L., Clesse, S., Cliche, J., Columbro, F., Connors, J. A., Coppolecchia, A., Coulton, W., Cubas, J., Cukierman, A., Curtis, D., Cuttaia, F., D’Alessandro, G., Dachlythra, K., de Bernardis, P., de Haan, T., de la Hoz, E., De Petris, M., Della Torre, S., Daz Garca, J. J., Dickinson, C., Diego-Palazuelos, P., Dobbs, M., Dotani, T., Douillet, D., Doumayrou, E., Duband, L., Ducout, A., Duff, S. M., Duval, J. M., Ebisawa, K., Elleflot, T., Eriksen, H. K., Errard, J., Essinger-Hileman, T., Farrens, S., Finelli, F., Flauger, R., Fleury-Frenette, K., Franceschet, C., Fuskeland, U., Galli, L., Galli, S., Galloway, M., Ganga, K., Gao, J. R., Genova-Santos, R. T., Georges, M., Gerbino, M., Gervasi, M., Ghigna, T., Giardiello, S., Gjerlw, E., Gonzles, R. Gonzlez, Gradziel, M. L., Grain, J., Grandsire, L., Grupp, F., Gruppuso, A., Gudmundsson, J. E., Halverson, N. W., Hamilton, J., Hargrave, P., Hasebe, T., Hasegawa, M., Hattori, M., Hazumi, M., Henrot-Versill, S., Hensley, B., Herman, D., Herranz, D., Hilton, G. C., Hivon, E., Hlozek, R. A., Hoang, D., Hornsby, A. L., Hoshino, Y., Ichiki, K., Iida, T., Ikemoto, T., Imada, H., Ishimura, K., Ishino, H., Jaehnig, G., Jones, M., Kaga, T., Kashima, S., Katayama, N., Kato, A., Kawasaki, T., Keskitalo, R., Kintziger, C., Kisner, T., Kobayashi, Y., Kogiso, N., Kogut, A., Kohri, K., Komatsu, E., Komatsu, K., Konishi, K., Krachmalnicoff, N., Kreykenbohm, I., Kuo, C. L., Kushino, A., Lamagna, L., Lanen, J. V., Laquaniello, G., Lattanzi, M., Lee, A. T., Leloup, C., Levrier, F., Linder, E., Link, M. J., Lonappan, A. I., Louis, T., Luzzi, G., Macias-Perez, J., Maciaszek, T., Maffei, B., Maino, D., Maki, M., Mandelli, S., Maris, M., Marquet, B., Martnez-Gonzlez, E., Martire, F. A., Masi, S., Massa, M., Masuzawa, M., Matarrese, S., Matsuda, F. T., Matsumura, T., Mele, L., Mennella, A., Migliaccio, M., Minami, Y., Mitsuda, K., Moggi, A., Monelli, M., Monfardini, A., Montgomery, J., Montier, L., Morgante, G., Mot, B., Murata, Y., Murphy, J. A., Nagai, M., Nagano, Y., Nagasaki, T., Nagata, R., Nakamura, S., Nakano, R., Namikawa, T., Nati, F., Natoli, P., Nerval, S., Neto Godry Farias, N., Nishibori, T., Nishino, H., Noviello, F., O’Neil, G. C., O’Sullivan, C., Odagiri, K., Ochi, H., Ogawa, H., Oguri, S., Ohsaki, H., Ohta, I. S., Okada, N., Pagano, L., Paiella, A., Paoletti, D., Pascual Cisneros, G., Passerini, A., Patanchon, G., Pelgrim, V., Peloton, J., Pettorino, V., Piacentini, F., Piat, M., Piccirilli, G., Pinsard, F., Pisano, G., Plesseria, J., Polenta, G., Poletti, D., Prouv, T., Puglisi, G., Rambaud, D., Raum, C., Realini, S., Reinecke, M., Reintsema, C. D., Remazeilles, M., Ritacco, A., Rosier, P., Roudil, G., Rubino-Martin, J., Russell, M., Sakurai, H., Sakurai, Y., Sandri, M., Sasaki, M., Savini, G., Scott, D., Seibert, J., Sekimoto, Y., Sherwin, B., Shinozaki, K., Shiraishi, M., Shirron, P., Shitvov, A., Signorelli, G., Smecher, G., Spinella, F., Starck, J., Stever, S., Stompor, R., Sudiwala, R., Sugiyama, S., Sullivan, R., Suzuki, A., Suzuki, J., Suzuki, T., Svalheim, T. L., Switzer, E., Takaku, R., Takakura, H., Takakura, S., Takase, Y., Takeda, Y., Tartari, A., Tavagnacco, D., Taylor, A., Taylor, E., Terao, Y., Terenzi, L., Thermeau, J., Thommesen, H., Thompson, K. L., Thorne, B., Toda, T., Tomasi, M., Tominaga, M., Trappe, N., Tristram, M., Tsuji, M., Tsujimoto, M., Tucker, C., Ueki, R., Ullom, J. N., Umemori, K., Vacher, L., Van Lanen, J., Vermeulen, G., Vielva, P., Villa, F., Vissers, M. R., Vittorio, N., Wandelt, B., Wang, W., Wehus, I. K., Weller, J., Westbrook, B., Weymann-Despres, G., Wilms, J., Winter, B., Wollack, E. J., Yamasaki, N. Y., Yoshida, T., Yumoto, J., Watanuki, K., Zacchei, A., Zannoni, M., and Zonca, A.

Abstract

Feedhorn- and orthomode transducer- (OMT) coupled transition edge sensor (TES) bolometers have been designed and micro-fabricated to meet the optical specifications of the LiteBIRD high frequency telescope (HFT) focal plane. We discuss the design and optical characterization of two LiteBIRD HFT detector types: dual-polarization, dual-frequency-band pixels with 195/280 GHz and 235/337 GHz band centers. Results show well-matched passbands between orthogonal polarization channels and frequency centers within 3% of the design values. The optical efficiency of each frequency channel is conservatively reported to be within the range 0.64−0.72, determined from the response to a cryogenic, temperature-controlled thermal source. These values are in good agreement with expectations and either exceed or are within 10% of the values used in the LiteBIRD sensitivity forecast. Lastly, we report a measurement of loss in Nb/SiNx/Nb microstrip at 100 mK and over the frequency range 200–350 GHz, which is comparable to values previously reported in the literature

Published
2022

24. In-flight polarization angle calibration for LiteBIRD: Blind challenge and cosmological implications

Author

Krachmalnicoff, N, Matsumura, T, De La Hoz, E, Basak, S, Gruppuso, A, Minami, Y, Baccigalupi, C, Komatsu, E, Martinez-Gonzalez, E, Vielva, P, Aumont, J, Aurlien, R, Azzoni, S, Banday, A, Barreiro, R, Bartolo, N, Bersanelli, M, Calabrese, E, Carones, A, Casas, F, Cheung, K, Chinone, Y, Columbro, F, De Bernardis, P, Diego-Palazuelos, P, Errard, J, Finelli, F, Fuskeland, U, Galloway, M, Genova-Santos, R, Gerbino, M, Ghigna, T, Giardiello, S, Gjerlow, E, Hazumi, M, Henrot-Versille, S, Kisner, T, Lamagna, L, Lattanzi, M, Levrier, F, Luzzi, G, Maino, D, Masi, S, Migliaccio, M, Montier, L, Morgante, G, Mot, B, Nagata, R, Nati, F, Natoli, P, Pagano, L, Paiella, A, Paoletti, D, Patanchon, G, Piacentini, F, Polenta, G, Poletti, D, Puglisi, G, Remazeilles, M, Rubino-Martin, J, Sasaki, M, Shiraishi, M, Signorelli, G, Stever, S, Tartari, A, Tristram, M, Tsuji, M, Vacher, L, Wehus, I, Zannoni, M, Krachmalnicoff N., Matsumura T., De La Hoz E., Basak S., Gruppuso A., Minami Y., Baccigalupi C., Komatsu E., Martinez-Gonzalez E., Vielva P., Aumont J., Aurlien R., Azzoni S., Banday A. J., Barreiro R. B., Bartolo N., Bersanelli M., Calabrese E., Carones A., Casas F. J., Cheung K., Chinone Y., Columbro F., De Bernardis P., Diego-Palazuelos P., Errard J., Finelli F., Fuskeland U., Galloway M., Genova-Santos R. T., Gerbino M., Ghigna T., Giardiello S., Gjerlow E., Hazumi M., Henrot-Versille S., Kisner T., Lamagna L., Lattanzi M., Levrier F., Luzzi G., Maino D., Masi S., Migliaccio M., Montier L., Morgante G., Mot B., Nagata R., Nati F., Natoli P., Pagano L., Paiella A., Paoletti D., Patanchon G., Piacentini F., Polenta G., Poletti D., Puglisi G., Remazeilles M., Rubino-Martin J., Sasaki M., Shiraishi M., Signorelli G., Stever S., Tartari A., Tristram M., Tsuji M., Vacher L., Wehus I. K., Zannoni M., Krachmalnicoff, N, Matsumura, T, De La Hoz, E, Basak, S, Gruppuso, A, Minami, Y, Baccigalupi, C, Komatsu, E, Martinez-Gonzalez, E, Vielva, P, Aumont, J, Aurlien, R, Azzoni, S, Banday, A, Barreiro, R, Bartolo, N, Bersanelli, M, Calabrese, E, Carones, A, Casas, F, Cheung, K, Chinone, Y, Columbro, F, De Bernardis, P, Diego-Palazuelos, P, Errard, J, Finelli, F, Fuskeland, U, Galloway, M, Genova-Santos, R, Gerbino, M, Ghigna, T, Giardiello, S, Gjerlow, E, Hazumi, M, Henrot-Versille, S, Kisner, T, Lamagna, L, Lattanzi, M, Levrier, F, Luzzi, G, Maino, D, Masi, S, Migliaccio, M, Montier, L, Morgante, G, Mot, B, Nagata, R, Nati, F, Natoli, P, Pagano, L, Paiella, A, Paoletti, D, Patanchon, G, Piacentini, F, Polenta, G, Poletti, D, Puglisi, G, Remazeilles, M, Rubino-Martin, J, Sasaki, M, Shiraishi, M, Signorelli, G, Stever, S, Tartari, A, Tristram, M, Tsuji, M, Vacher, L, Wehus, I, Zannoni, M, Krachmalnicoff N., Matsumura T., De La Hoz E., Basak S., Gruppuso A., Minami Y., Baccigalupi C., Komatsu E., Martinez-Gonzalez E., Vielva P., Aumont J., Aurlien R., Azzoni S., Banday A. J., Barreiro R. B., Bartolo N., Bersanelli M., Calabrese E., Carones A., Casas F. J., Cheung K., Chinone Y., Columbro F., De Bernardis P., Diego-Palazuelos P., Errard J., Finelli F., Fuskeland U., Galloway M., Genova-Santos R. T., Gerbino M., Ghigna T., Giardiello S., Gjerlow E., Hazumi M., Henrot-Versille S., Kisner T., Lamagna L., Lattanzi M., Levrier F., Luzzi G., Maino D., Masi S., Migliaccio M., Montier L., Morgante G., Mot B., Nagata R., Nati F., Natoli P., Pagano L., Paiella A., Paoletti D., Patanchon G., Piacentini F., Polenta G., Poletti D., Puglisi G., Remazeilles M., Rubino-Martin J., Sasaki M., Shiraishi M., Signorelli G., Stever S., Tartari A., Tristram M., Tsuji M., Vacher L., Wehus I. K., and Zannoni M.

Abstract

We present a demonstration of the in-flight polarization angle calibration for the JAXA/ISAS second strategic large class mission, LiteBIRD, and estimate its impact on the measurement of the tensor-to-scalar ratio parameter, r, using simulated data. We generate a set of simulated sky maps with CMB and polarized foreground emission, and inject instrumental noise and polarization angle offsets to the 22 (partially overlapping) LiteBIRD frequency channels. Our in-flight angle calibration relies on nulling the EB cross correlation of the polarized signal in each channel. This calibration step has been carried out by two independent groups with a blind analysis, allowing an accuracy of the order of a few arc-minutes to be reached on the estimate of the angle offsets. Both the corrected and uncorrected multi-frequency maps are propagated through the foreground cleaning step, with the goal of computing clean CMB maps. We employ two component separation algorithms, the Bayesian-Separation of Components and Residuals Estimate Tool (B-SeCRET), and the Needlet Internal Linear Combination (NILC). We find that the recovered CMB maps obtained with algorithms that do not make any assumptions about the foreground properties, such as NILC, are only mildly affected by the angle miscalibration. However, polarization angle offsets strongly bias results obtained with the parametric fitting method. Once the miscalibration angles are corrected by EB nulling prior to the component separation, both component separation algorithms result in an unbiased estimation of the r parameter. While this work is motivated by the conceptual design study for LiteBIRD, its framework can be broadly applied to any CMB polarization experiment. In particular, the combination of simulation plus blind analysis provides a robust forecast by taking into account not only detector sensitivity but also systematic effects.

Published
2022

30. LiteBIRD: An All-Sky Cosmic Microwave Background Probe of Inflation

Author

Lee, Adrian T, Ade, P. A. R, Akiba, Y, Alonso, D, Arnold, K, Aumont, J, Austermann, J, Baccigalupi, C, Banday, A. J, Banerji, R, Barreiro, R. B, Basak, S, Beall, J, Beckman, S, Bersanelli, M, Borrill, J, Boulanger, F, Brown, M. L, Bucher, M, Buzzelli, A, Calabrese, E, Casas, F. J, Challinor, A, Chan, V, Chinone, Y, Cliche, J.-F, Columbro, F, Cukierman, A, Curtis, D, Danto, P, de Bernardis, P, de Haan, T, De Petris, M, Dickinson, C, Dobbs, M, Dotani, T, Duband, L, Ducout, A, Du, S, Duivenvoorden, A, Duval, J.-M, Ebisawa, K, Elleflot, T, Enokida, H, Eriksen, H. K, Errard, J, Essinger-Hileman, T, Finelli, F, Flauger, R, Franceschet, C, Fuskeland, U, Ganga, K, Gao, J.-R, Genovo-Santos, R, Ghigna, T, Gomez, A, Gradziel, M. L, Grain, J, Grupp, F, Gruppuso, A, Gudmundsson, J. E, Halverson, N. W, Hargrave, P, Hasebe, T, Hasegawa, M, Hattori, M, Hazumi, M, Henrot-Versille, S, Herranz, D, Hill, C, Hilton, G, Hirota, Y, Hivon, E, Hlozek, R, Hoang, D.-T, Hubmayr, J, Ichiki, K, Iida, T, Imada, H, Ishimura, K, Ishino, H, Jaehnig, G. C, Jones, M, Kaga, T, Kashima, S, Kataoka, Y, Katayama, N, Kawasaki, T, Keskitalo, R, Kibayashi, A, Kikuchi, T, Kimura, K, Kisner, T, Kobayashi, Y, Kogiso, N, Kogut, A, Kohri, K, Komatsu, E, Komatsu, K, Konishi, K, Krachmalnico, N, Kuo, C. L, Kurinsky, N, Kushino, A, Kuwata-Gonokami, M, Lamagna, L, Lattanzi, M, Lee, A. T, Linder, E, Maffei, B, Maino, D, Maki, M, Mangilli, A, Martinez-Gonzalez, E, Masi, S, Mathon, R, Matsumura, T, Mennella, A, Migliaccio, M, Minami, Y, Mistuda, K, Molinari, D, Montier, L, Morgante, G, Mot, B, Murata, Y, Murphy, J. A, Nagai, M, Nagata, R, Nakamura, S, Namikawa, T, Natoli, P, Nerval, S, Nishibori, T, Nishino, H, Nomura, Y, Noviello, F, O'Sullivan, C, Ochi, H, Ogawa, H, Ohsaki, H, Ohta, I, Okada, N, Pagano, L, Paiella, A, Paoletti, D, Patanchon, G, Piacentini, F, Pisano, G, Polenta, G, Poletti, D, Prouve, T, Puglisi, G, Rambaud, D, Raum, C, Realini, S, Remazeilles, M, Roudil, G, Rubino-Martin, J. A, Russell, M, Sakurai, H, Sakurai, Y, Sandri, M, Savini, G, Scott, D, Sekimoto, Y, Sherwin, B. D, Shinozaki, K, Shiraishi, M, Shirron, P, Signorelli, G, Smecher, G, Spizzi, P, Stever, S. L, Stompor, R, Sugai, H, Sugiyama, S, Suzuki, A, Suzuki, J, Switzer, E, Takaku, R, Takakura, H, Takakura, S, Takeda, Y, Taylor, A, Taylor, E, Terao, Y, Thompson, K. L, Thorne, B, Tomasi, M, Tomida, H, Trappe, N, Tristram, M, Tsuji, M, Tsujimoto, M, Tucker, C, Ullom, J, Uozumi, S, Utsunomiya, S, Van Lanen, J, Vermeulen, G, Vielva, P, Villa, F, Vissers, M, Vittorio, N, Voisin, F, Walker, I, Watanabe, N, Wehus, I, Weller, J, Westbrook, B, Winter, B, Wollack, E, Yamamoto, R, Yamasaki, N. Y, Yanagisawa, M, Yoshida, T, Yumoto, J, Zannoni, M, and Zonca, A

Subjects
Astrophysics
Abstract

The LiteBIRD mission will map polarized fluctuations in the cosmic microwave background (CMB) to search for the signature of gravitational waves from inflation, potentially opening a window on the Universe a fraction of a second after the Big Bang. CMB measurements from space give access to the largest angular scales and the full frequency range to constrain Galactic foregrounds, and LiteBIRD has been designed to take best advantage of the unique window of space. LiteBIRD will have a powerful ability to separate Galactic foreground emission from the CMB due to its 15 frequency bands spaced between 40 and 402 GHz and sensitive 100-mK bolometers. LiteBIRD will provide stringent control of systematic errors due to the benign thermal environment at the second Lagrange point, L2, 20-K rapidly rotating half-wave plates on each telescope, and the ability to crosscheck its results by measuring both the reionization and recombination peaks in the B-mode power spectrum. LiteBIRD would be the next step in the series of CMB space missions, COBE, WMAP, and Planck, each of which has given landmark scientific discoveries.

Published
2019

32. New advances to prepare GYSELA-X code for exascale global gyrokinetic plasma turbulence simulations: porting on GPU and ARM architectures

Author

Grandgirard, Virginie, Obrejan, Kevin, Midou, Dorian, Asahi, Y, Bernard, P-E, Bigot, J, Bourne, E, Dechard, J, Dif- Pradalier, G, Donnel, P, Garbet, X, Gueroudji, A, Hager, G, Murai, H, Ould-Ruis, Yacine, Padioleau, T, Nguyen, L, Peybernes, M, Sarazin, Y, Sato, M, Tsuji, M, Vezolle, P, Institut de Recherche sur la Fusion par confinement Magnétique (IRFM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Japan Atomic Energy Agency, Hewlett Packard Enterprise (Hewlett Packard) (HPE), Maison de la Simulation (MDLS), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de Recherche en Informatique et en Automatique (Inria)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), AS+ Groupe EOLEN, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), RIKEN Center for Computational Science [Kobe] (RIKEN CCS), RIKEN - Institute of Physical and Chemical Research [Japon] (RIKEN), Data Aware Large Scale Computing (DATAMOVE ), Inria Grenoble - Rhône-Alpes, Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)-Laboratoire d'Informatique de Grenoble (LIG), Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Ecole Polytechnique Fédérale de Lausanne (EPFL), the Association for Computing Machinery (ACM), and the Swiss National Supercomputing Centre (CSCS)

Subjects
[NLIN]Nonlinear Sciences [physics]
Abstract

International audience

Published
2022

33. Comparative study of bioactivity of collagen scaffolds coated with graphene oxide and reduced graphene oxide

Author

Kanayama I, Miyaji H, Takita H, Nishida E, Tsuji M, Fugetsu B, Sun L, Inoue K, Ibara A, Akasaka T, Sugaya T, and Kawanami M

Subjects
Medicine (General), R5-920
Abstract

Izumi Kanayama,1 Hirofumi Miyaji,1 Hiroko Takita,2 Erika Nishida,1 Maiko Tsuji,3 Bunshi Fugetsu,4,5 Ling Sun,4,5 Kana Inoue,1 Asako Ibara,1 Tsukasa Akasaka,6 Tsutomu Sugaya,1 Masamitsu Kawanami1 1Department of Periodontology and Endodontology, 2Support Section for Education and Research, Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan; 3Mitsubishi Gas Chemical Company, Inc., Tokyo, Japan; 4Division of Frontier Research, Research Department, Creative Research Institution Sousei, 5Graduate School of Environmental Science, 6Department of Biomedical, Dental Materials and Engineering, Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan Background: Graphene oxide (GO) is a single layer carbon sheet with a thickness of less than 1 nm. GO has good dispersibility due to surface modifications with numerous functional groups. Reduced graphene oxide (RGO) is produced via the reduction of GO, and has lower dispersibility. We examined the bioactivity of GO and RGO films, and collagen scaffolds coated with GO and RGO. Methods: GO and RGO films were fabricated on a culture dish. Some GO films were chemically reduced using either ascorbic acid or sodium hydrosulfite solution, resulting in preparation of RGO films. The biological properties of each film were evaluated by scanning electron microscopy (SEM), atomic force microscopy, calcium adsorption tests, and MC3T3-E1 cell seeding. Subsequently, GO- and RGO-coated collagen scaffolds were prepared and characterized by SEM and compression tests. Each scaffold was implanted into subcutaneous tissue on the backs of rats. Measurements of DNA content and cell ingrowth areas of implanted scaffolds were performed 10 days post-surgery.Results: The results show that GO and RGO possess different biological properties. Calcium adsorption and alkaline phosphatase activity were strongly enhanced by RGO, suggesting that RGO is effective for osteogenic differentiation. SEM showed that RGO-modified collagen scaffolds have rough, irregular surfaces. The compressive strengths of GO- and RGO-coated scaffolds were approximately 1.7-fold and 2.7-fold greater, respectively, when compared with the non-coated scaffold. Tissue ingrowth rate was 39% in RGO-coated scaffolds, as compared to 20% in the GO-coated scaffold and 16% in the non-coated scaffold.Conclusion: In summary, these results suggest that GO and RGO coatings provide different biological properties to collagen scaffolds, and that RGO-coated scaffolds are more bioactive than GO-coated scaffolds. Keywords: GO, RGO, tissue engineering, regenerative scaffold, cell ingrowth, biomaterials

Published
2014

35. Updated Design of the CMB Polarization Experiment Satellite LiteBIRD

Author

Sugai, H, Ade, P, Akiba, Y, Alonso, D, Arnold, K, Aumont, J, Austermann, J, Baccigalupi, C, Banday, A, Banerji, R, Barreiro, R, Basak, S, Beall, J, Beckman, S, Bersanelli, M, Borrill, J, Boulanger, F, Brown, M, Bucher, M, Buzzelli, A, Calabrese, E, Casas, F, Challinor, A, Chan, V, Chinone, Y, Cliche, J, Columbro, F, Cukierman, A, Curtis, D, Danto, P, de Bernardis, P, de Haan, T, De Petris, M, Dickinson, C, Dobbs, M, Dotani, T, Duband, L, Ducout, A, Duff, S, Duivenvoorden, A, Duval, J, Ebisawa, K, Elleflot, T, Enokida, H, Eriksen, H, Errard, J, Essinger-Hileman, T, Finelli, F, Flauger, R, Franceschet, C, Fuskeland, U, Ganga, K, Gao, J, Génova-Santos, R, Ghigna, T, Gomez, A, Gradziel, M, Grain, J, Grupp, F, Gruppuso, A, Gudmundsson, J, Halverson, N, Hargrave, P, Hasebe, T, Hasegawa, M, Hattori, M, Hazumi, M, Henrot-Versille, S, Herranz, D, Hill, C, Hilton, G, Hirota, Y, Hivon, E, Hlozek, R, Hoang, D, Hubmayr, J, Ichiki, K, Iida, T, Imada, H, Ishimura, K, Ishino, H, Jaehnig, G, Jones, M, Kaga, T, Kashima, S, Kataoka, Y, Katayama, N, Kawasaki, T, Keskitalo, R, Kibayashi, A, Kikuchi, T, Kimura, K, Kisner, T, Kobayashi, Y, Kogiso, N, Kogut, A, Kohri, K, Komatsu, E, Komatsu, K, Konishi, K, Krachmalnicoff, N, Kuo, C, Kurinsky, N, Kushino, A, Kuwata-Gonokami, M, Lamagna, L, Lattanzi, M, Lee, A, Linder, E, Maffei, B, Maino, D, Maki, M, Mangilli, A, Martínez-González, E, Masi, S, Mathon, R, Matsumura, T, Mennella, A, Migliaccio, M, Minami, Y, Mistuda, K, Molinari, D, Montier, L, Morgante, G, Mot, B, Murata, Y, Murphy, J, Nagai, M, Nagata, R, Nakamura, S, Namikawa, T, Natoli, P, Nerval, S, Nishibori, T, Nishino, H, Nomura, Y, Noviello, F, O’Sullivan, C, Ochi, H, Ogawa, H, Ohsaki, H, Ohta, I, Okada, N, Pagano, L, Paiella, A, Paoletti, D, Patanchon, G, Piacentini, F, Pisano, G, Polenta, G, Poletti, D, Prouvé, T, Puglisi, G, Rambaud, D, Raum, C, Realini, S, Remazeilles, M, Roudil, G, Rubiño-Martín, J, Russell, M, Sakurai, H, Sakurai, Y, Sandri, M, Savini, G, Scott, D, Sekimoto, Y, Sherwin, B, Shinozaki, K, Shiraishi, M, Shirron, P, Signorelli, G, Smecher, G, Spizzi, P, Stever, S, Stompor, R, Sugiyama, S, Suzuki, A, Suzuki, J, Switzer, E, Takaku, R, Takakura, H, Takakura, S, Takeda, Y, Taylor, A, Taylor, E, Terao, Y, Thompson, K, Thorne, B, Tomasi, M, Tomida, H, Trappe, N, Tristram, M, Tsuji, M, Tsujimoto, M, Tucker, C, Ullom, J, Uozumi, S, Utsunomiya, S, Van Lanen, J, Vermeulen, G, Vielva, P, Villa, F, Vissers, M, Vittorio, N, Voisin, F, Walker, I, Watanabe, N, Wehus, I, Weller, J, Westbrook, B, Winter, B, Wollack, E, Yamamoto, R, Yamasaki, N, Yanagisawa, M, Yoshida, T, Yumoto, J, Zannoni, M, Zonca, A, Sugai, H., Ade, P. A. R., Akiba, Y., Alonso, D., Arnold, K., Aumont, J., Austermann, J., Baccigalupi, C., Banday, A. J., Banerji, R., Barreiro, R. B., Basak, S., Beall, J., Beckman, S., Bersanelli, M., Borrill, J., Boulanger, F., Brown, M. L., Bucher, M., Buzzelli, A., Calabrese, E., Casas, F. J., Challinor, A., Chan, V., Chinone, Y., Cliche, J. -F., Columbro, F., Cukierman, A., Curtis, D., Danto, P., de Bernardis, P., de Haan, T., De Petris, M., Dickinson, C., Dobbs, M., Dotani, T., Duband, L., Ducout, A., Duff, S., Duivenvoorden, A., Duval, J. -M., Ebisawa, K., Elleflot, T., Enokida, H., Eriksen, H. K., Errard, J., Essinger-Hileman, T., Finelli, F., Flauger, R., Franceschet, C., Fuskeland, U., Ganga, K., Gao, J. -R., Génova-Santos, R., Ghigna, T., Gomez, A., Gradziel, M. L., Grain, J., Grupp, F., Gruppuso, A., Gudmundsson, J. E., Halverson, N. W., Hargrave, P., Hasebe, T., Hasegawa, M., Hattori, M., Hazumi, M., Henrot-Versille, S., Herranz, D., Hill, C., Hilton, G., Hirota, Y., Hivon, E., Hlozek, R., Hoang, D. -T., Hubmayr, J., Ichiki, K., Iida, T., Imada, H., Ishimura, K., Ishino, H., Jaehnig, G. C., Jones, M., Kaga, T., Kashima, S., Kataoka, Y., Katayama, N., Kawasaki, T., Keskitalo, R., Kibayashi, A., Kikuchi, T., Kimura, K., Kisner, T., Kobayashi, Y., Kogiso, N., Kogut, A., Kohri, K., Komatsu, E., Komatsu, K., Konishi, K., Krachmalnicoff, N., Kuo, C. L., Kurinsky, N., Kushino, A., Kuwata-Gonokami, M., Lamagna, L., Lattanzi, M., Lee, A. T., Linder, E., Maffei, B., Maino, D., Maki, M., Mangilli, A., Martínez-González, E., Masi, S., Mathon, R., Matsumura, T., Mennella, A., Migliaccio, M., Minami, Y., Mistuda, K., Molinari, D., Montier, L., Morgante, G., Mot, B., Murata, Y., Murphy, J. A., Nagai, M., Nagata, R., Nakamura, S., Namikawa, T., Natoli, P., Nerval, S., Nishibori, T., Nishino, H., Nomura, Y., Noviello, F., O’Sullivan, C., Ochi, H., Ogawa, H., Ohsaki, H., Ohta, I., Okada, N., Pagano, L., Paiella, A., Paoletti, D., Patanchon, G., Piacentini, F., Pisano, G., Polenta, G., Poletti, D., Prouvé, T., Puglisi, G., Rambaud, D., Raum, C., Realini, S., Remazeilles, M., Roudil, G., Rubiño-Martín, J. A., Russell, M., Sakurai, H., Sakurai, Y., Sandri, M., Savini, G., Scott, D., Sekimoto, Y., Sherwin, B. D., Shinozaki, K., Shiraishi, M., Shirron, P., Signorelli, G., Smecher, G., Spizzi, P., Stever, S. L., Stompor, R., Sugiyama, S., Suzuki, A., Suzuki, J., Switzer, E., Takaku, R., Takakura, H., Takakura, S., Takeda, Y., Taylor, A., Taylor, E., Terao, Y., Thompson, K. L., Thorne, B., Tomasi, M., Tomida, H., Trappe, N., Tristram, M., Tsuji, M., Tsujimoto, M., Tucker, C., Ullom, J., Uozumi, S., Utsunomiya, S., Van Lanen, J., Vermeulen, G., Vielva, P., Villa, F., Vissers, M., Vittorio, N., Voisin, F., Walker, I., Watanabe, N., Wehus, I., Weller, J., Westbrook, B., Winter, B., Wollack, E., Yamamoto, R., Yamasaki, N. Y., Yanagisawa, M., Yoshida, T., Yumoto, J., Zannoni, M., Zonca, A., Sugai, H, Ade, P, Akiba, Y, Alonso, D, Arnold, K, Aumont, J, Austermann, J, Baccigalupi, C, Banday, A, Banerji, R, Barreiro, R, Basak, S, Beall, J, Beckman, S, Bersanelli, M, Borrill, J, Boulanger, F, Brown, M, Bucher, M, Buzzelli, A, Calabrese, E, Casas, F, Challinor, A, Chan, V, Chinone, Y, Cliche, J, Columbro, F, Cukierman, A, Curtis, D, Danto, P, de Bernardis, P, de Haan, T, De Petris, M, Dickinson, C, Dobbs, M, Dotani, T, Duband, L, Ducout, A, Duff, S, Duivenvoorden, A, Duval, J, Ebisawa, K, Elleflot, T, Enokida, H, Eriksen, H, Errard, J, Essinger-Hileman, T, Finelli, F, Flauger, R, Franceschet, C, Fuskeland, U, Ganga, K, Gao, J, Génova-Santos, R, Ghigna, T, Gomez, A, Gradziel, M, Grain, J, Grupp, F, Gruppuso, A, Gudmundsson, J, Halverson, N, Hargrave, P, Hasebe, T, Hasegawa, M, Hattori, M, Hazumi, M, Henrot-Versille, S, Herranz, D, Hill, C, Hilton, G, Hirota, Y, Hivon, E, Hlozek, R, Hoang, D, Hubmayr, J, Ichiki, K, Iida, T, Imada, H, Ishimura, K, Ishino, H, Jaehnig, G, Jones, M, Kaga, T, Kashima, S, Kataoka, Y, Katayama, N, Kawasaki, T, Keskitalo, R, Kibayashi, A, Kikuchi, T, Kimura, K, Kisner, T, Kobayashi, Y, Kogiso, N, Kogut, A, Kohri, K, Komatsu, E, Komatsu, K, Konishi, K, Krachmalnicoff, N, Kuo, C, Kurinsky, N, Kushino, A, Kuwata-Gonokami, M, Lamagna, L, Lattanzi, M, Lee, A, Linder, E, Maffei, B, Maino, D, Maki, M, Mangilli, A, Martínez-González, E, Masi, S, Mathon, R, Matsumura, T, Mennella, A, Migliaccio, M, Minami, Y, Mistuda, K, Molinari, D, Montier, L, Morgante, G, Mot, B, Murata, Y, Murphy, J, Nagai, M, Nagata, R, Nakamura, S, Namikawa, T, Natoli, P, Nerval, S, Nishibori, T, Nishino, H, Nomura, Y, Noviello, F, O’Sullivan, C, Ochi, H, Ogawa, H, Ohsaki, H, Ohta, I, Okada, N, Pagano, L, Paiella, A, Paoletti, D, Patanchon, G, Piacentini, F, Pisano, G, Polenta, G, Poletti, D, Prouvé, T, Puglisi, G, Rambaud, D, Raum, C, Realini, S, Remazeilles, M, Roudil, G, Rubiño-Martín, J, Russell, M, Sakurai, H, Sakurai, Y, Sandri, M, Savini, G, Scott, D, Sekimoto, Y, Sherwin, B, Shinozaki, K, Shiraishi, M, Shirron, P, Signorelli, G, Smecher, G, Spizzi, P, Stever, S, Stompor, R, Sugiyama, S, Suzuki, A, Suzuki, J, Switzer, E, Takaku, R, Takakura, H, Takakura, S, Takeda, Y, Taylor, A, Taylor, E, Terao, Y, Thompson, K, Thorne, B, Tomasi, M, Tomida, H, Trappe, N, Tristram, M, Tsuji, M, Tsujimoto, M, Tucker, C, Ullom, J, Uozumi, S, Utsunomiya, S, Van Lanen, J, Vermeulen, G, Vielva, P, Villa, F, Vissers, M, Vittorio, N, Voisin, F, Walker, I, Watanabe, N, Wehus, I, Weller, J, Westbrook, B, Winter, B, Wollack, E, Yamamoto, R, Yamasaki, N, Yanagisawa, M, Yoshida, T, Yumoto, J, Zannoni, M, Zonca, A, Sugai, H., Ade, P. A. R., Akiba, Y., Alonso, D., Arnold, K., Aumont, J., Austermann, J., Baccigalupi, C., Banday, A. J., Banerji, R., Barreiro, R. B., Basak, S., Beall, J., Beckman, S., Bersanelli, M., Borrill, J., Boulanger, F., Brown, M. L., Bucher, M., Buzzelli, A., Calabrese, E., Casas, F. J., Challinor, A., Chan, V., Chinone, Y., Cliche, J. -F., Columbro, F., Cukierman, A., Curtis, D., Danto, P., de Bernardis, P., de Haan, T., De Petris, M., Dickinson, C., Dobbs, M., Dotani, T., Duband, L., Ducout, A., Duff, S., Duivenvoorden, A., Duval, J. -M., Ebisawa, K., Elleflot, T., Enokida, H., Eriksen, H. K., Errard, J., Essinger-Hileman, T., Finelli, F., Flauger, R., Franceschet, C., Fuskeland, U., Ganga, K., Gao, J. -R., Génova-Santos, R., Ghigna, T., Gomez, A., Gradziel, M. L., Grain, J., Grupp, F., Gruppuso, A., Gudmundsson, J. E., Halverson, N. W., Hargrave, P., Hasebe, T., Hasegawa, M., Hattori, M., Hazumi, M., Henrot-Versille, S., Herranz, D., Hill, C., Hilton, G., Hirota, Y., Hivon, E., Hlozek, R., Hoang, D. -T., Hubmayr, J., Ichiki, K., Iida, T., Imada, H., Ishimura, K., Ishino, H., Jaehnig, G. C., Jones, M., Kaga, T., Kashima, S., Kataoka, Y., Katayama, N., Kawasaki, T., Keskitalo, R., Kibayashi, A., Kikuchi, T., Kimura, K., Kisner, T., Kobayashi, Y., Kogiso, N., Kogut, A., Kohri, K., Komatsu, E., Komatsu, K., Konishi, K., Krachmalnicoff, N., Kuo, C. L., Kurinsky, N., Kushino, A., Kuwata-Gonokami, M., Lamagna, L., Lattanzi, M., Lee, A. T., Linder, E., Maffei, B., Maino, D., Maki, M., Mangilli, A., Martínez-González, E., Masi, S., Mathon, R., Matsumura, T., Mennella, A., Migliaccio, M., Minami, Y., Mistuda, K., Molinari, D., Montier, L., Morgante, G., Mot, B., Murata, Y., Murphy, J. A., Nagai, M., Nagata, R., Nakamura, S., Namikawa, T., Natoli, P., Nerval, S., Nishibori, T., Nishino, H., Nomura, Y., Noviello, F., O’Sullivan, C., Ochi, H., Ogawa, H., Ohsaki, H., Ohta, I., Okada, N., Pagano, L., Paiella, A., Paoletti, D., Patanchon, G., Piacentini, F., Pisano, G., Polenta, G., Poletti, D., Prouvé, T., Puglisi, G., Rambaud, D., Raum, C., Realini, S., Remazeilles, M., Roudil, G., Rubiño-Martín, J. A., Russell, M., Sakurai, H., Sakurai, Y., Sandri, M., Savini, G., Scott, D., Sekimoto, Y., Sherwin, B. D., Shinozaki, K., Shiraishi, M., Shirron, P., Signorelli, G., Smecher, G., Spizzi, P., Stever, S. L., Stompor, R., Sugiyama, S., Suzuki, A., Suzuki, J., Switzer, E., Takaku, R., Takakura, H., Takakura, S., Takeda, Y., Taylor, A., Taylor, E., Terao, Y., Thompson, K. L., Thorne, B., Tomasi, M., Tomida, H., Trappe, N., Tristram, M., Tsuji, M., Tsujimoto, M., Tucker, C., Ullom, J., Uozumi, S., Utsunomiya, S., Van Lanen, J., Vermeulen, G., Vielva, P., Villa, F., Vissers, M., Vittorio, N., Voisin, F., Walker, I., Watanabe, N., Wehus, I., Weller, J., Westbrook, B., Winter, B., Wollack, E., Yamamoto, R., Yamasaki, N. Y., Yanagisawa, M., Yoshida, T., Yumoto, J., Zannoni, M., and Zonca, A.

Abstract

Recent developments of transition-edge sensors (TESs), based on extensive experience in ground-based experiments, have been making the sensor techniques mature enough for their application on future satellite cosmic microwave background (CMB) polarization experiments. LiteBIRD is in the most advanced phase among such future satellites, targeting its launch in Japanese Fiscal Year 2027 (2027FY) with JAXA’s H3 rocket. It will accommodate more than 4000 TESs in focal planes of reflective low-frequency and refractive medium-and-high-frequency telescopes in order to detect a signature imprinted on the CMB by the primordial gravitational waves predicted in cosmic inflation. The total wide frequency coverage between 34 and 448 GHz enables us to extract such weak spiral polarization patterns through the precise subtraction of our Galaxy’s foreground emission by using spectral differences among CMB and foreground signals. Telescopes are cooled down to 5 K for suppressing thermal noise and contain polarization modulators with transmissive half-wave plates at individual apertures for separating sky polarization signals from artificial polarization and for mitigating from instrumental 1/f noise. Passive cooling by using V-grooves supports active cooling with mechanical coolers as well as adiabatic demagnetization refrigerators. Sky observations from the second Sun–Earth Lagrangian point, L2, are planned for 3 years. An international collaboration between Japan, the USA, Canada, and Europe is sharing various roles. In May 2019, the Institute of Space and Astronautical Science, JAXA, selected LiteBIRD as the strategic large mission No. 2.

Published
2020

40. In-flight polarization angle calibration for LiteBIRD: blind challenge and cosmological implications

Author

Krachmalnicoff, N., additional, Matsumura, T., additional, de la Hoz, E., additional, Basak, S., additional, Gruppuso, A., additional, Minami, Y., additional, Baccigalupi, C., additional, Komatsu, E., additional, Martínez-González, E., additional, Vielva, P., additional, Aumont, J., additional, Aurlien, R., additional, Azzoni, S., additional, Banday, A.J., additional, Barreiro, R.B., additional, Bartolo, N., additional, Bersanelli, M., additional, Calabrese, E., additional, Carones, A., additional, Casas, F.J., additional, Cheung, K., additional, Chinone, Y., additional, Columbro, F., additional, de Bernardis, P., additional, Diego-Palazuelos, P., additional, Errard, J., additional, Finelli, F., additional, Fuskeland, U., additional, Galloway, M., additional, Genova-Santos, R.T., additional, Gerbino, M., additional, Ghigna, T., additional, Giardiello, S., additional, Gjerløw, E., additional, Hazumi, M., additional, Henrot-Versillé, S., additional, Kisner, T., additional, Lamagna, L., additional, Lattanzi, M., additional, Levrier, F., additional, Luzzi, G., additional, Maino, D., additional, Masi, S., additional, Migliaccio, M., additional, Montier, L., additional, Morgante, G., additional, Mot, B., additional, Nagata, R., additional, Nati, F., additional, Natoli, P., additional, Pagano, L., additional, Paiella, A., additional, Paoletti, D., additional, Patanchon, G., additional, Piacentini, F., additional, Polenta, G., additional, Poletti, D., additional, Puglisi, G., additional, Remazeilles, M., additional, Rubino-Martin, J., additional, Sasaki, M., additional, Shiraishi, M., additional, Signorelli, G., additional, Stever, S., additional, Tartari, A., additional, Tristram, M., additional, Tsuji, M., additional, Vacher, L., additional, Wehus, I.K., additional, and Zannoni, M., additional

Published
2022
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46. Rivaroxaban Monotherapy in Patients With Atrial Fibrillation After Coronary Stenting

Author

Matoba, Tetsuya, primary, Yasuda, Satoshi, additional, Kaikita, Koichi, additional, Akao, Masaharu, additional, Ako, Junya, additional, Nakamura, Masato, additional, Miyauchi, Katsumi, additional, Hagiwara, Nobuhisa, additional, Kimura, Kazuo, additional, Hirayama, Atsushi, additional, Matsui, Kunihiko, additional, Ogawa, Hisao, additional, Matoba, Tetsuya, additional, Koretsune, Yukihiro, additional, Hiro, Takafumi, additional, Sumiyoshi, Tetsuya, additional, Kimura, Kazumi, additional, Hashimoto, Yoichiro, additional, Hirano, Teruyuki, additional, Daida, Hiroyuki, additional, Okada, Yasushi, additional, Yamazaki, Tsutomu, additional, Nakamura, A., additional, Tamiya, E., additional, Yamamoto, T., additional, Suetake, S., additional, Noguchi, T., additional, Nakamura, S., additional, Matsumura, A., additional, Kojima, J., additional, Suwa, S., additional, Yamaguchi, H., additional, Kaikita, K., additional, Yasu, T., additional, Nakajima, A., additional, Yamada, T., additional, Arai, H., additional, Hata, Y., additional, Sakanashi, T., additional, Tateishi, H., additional, Nakayama, T., additional, Nozaki, Y., additional, Akao, M., additional, Okumura, Y., additional, Tokue, M., additional, Kuroki, N., additional, Maruyama, Y., additional, Matoba, T., additional, Hagiwara, N., additional, Suzuki, H., additional, Nishida, Y., additional, Ajioka, M., additional, Yumoto, K., additional, Shimizu, S., additional, Aoyama, T., additional, Shimomura, H., additional, Takeda, T., additional, Oshiro, K., additional, Sugishita, N., additional, Shibata, Y., additional, Otonari, T., additional, Kihara, H., additional, Ogawa, H., additional, Ohno, A., additional, Hazama, M., additional, Shimizu, M., additional, Tsukahara, K., additional, Haruta, S., additional, Wakeyama, T., additional, Haruna, T., additional, Ito, M., additional, Fujii, K., additional, Atsuchi, N., additional, Sata, M., additional, Kimura, K., additional, Hasebe, N., additional, Kobayasi, Y., additional, Ohsato, K., additional, Hironaga, K., additional, Naganuma, Y., additional, Anzaki, K., additional, Oiwa, K., additional, Okazaki, S., additional, Nakagawa, Y., additional, Tokuhiro, K., additional, Tanaka, K., additional, Momose, T., additional, Fukushima, Y., additional, Kametani, R., additional, Kawamitsu, K., additional, Saito, Y., additional, Akashi, S., additional, Kumagai, K., additional, Eshima, K., additional, Tobaru, T., additional, Seo, T., additional, Okuhara, K., additional, Kozuma, K., additional, Ikari, Y., additional, Takahashi, T., additional, Michishita, I., additional, Fujikura, H., additional, Momomura, S., additional, Yamamoto, Y., additional, Otomo, K., additional, Matsubara, T., additional, Tashiro, H., additional, Inoue, T., additional, Ishihara, M., additional, Shiojima, I., additional, Tachibana, E., additional, Ako, J., additional, Sumii, K., additional, Yamamoto, N., additional, Ohmura, N., additional, Nakamura, T., additional, Morita, Y., additional, Takahashi, N., additional, Watanabe, K., additional, Fujinaga, H., additional, Maruyama, M., additional, Oka, T., additional, Shirayama, T., additional, Amano, T., additional, Fukui, K., additional, Ando, K., additional, Oshima, S., additional, Kagiyama, S., additional, Teragawa, H., additional, Yuge, M., additional, Ono, S., additional, Koga, T., additional, Fujiu, K., additional, Kuwabara, M., additional, Ohya, Y., additional, Yumoto, Y., additional, Kuji, N., additional, Ikemura, M., additional, Kario, K., additional, Chatani, K., additional, Sato, K., additional, Miyagi, H., additional, Murakami, M., additional, Saito, K., additional, Hoshiga, M., additional, Sato, S., additional, Kubo, N., additional, Sakamoto, Y., additional, Ashida, K., additional, Sakamoto, H., additional, Murasaki, S., additional, Uehara, H., additional, Akasaka, T., additional, Ooba, Y., additional, Nakahara, S., additional, Hanaoka, Y., additional, Nishimiya, T., additional, Tsunoda, R., additional, Onuma, Y., additional, Higuchi, S., additional, Tani, A., additional, Wada, A., additional, Kato, M., additional, Obata, H., additional, Higuchi, Y., additional, Endo, T., additional, Katou, R., additional, Matsunaga, T., additional, Matsuoka, T., additional, Noguchi, H., additional, Usui, M., additional, Hayashi, T., additional, Otsuji, Y., additional, Osaki, T., additional, Zaizen, H., additional, Yoshihara, H., additional, Kadota, K., additional, Hirose, T., additional, Miyazawa, T., additional, Mori, A., additional, Takano, M., additional, Shimizu, W., additional, Wake, M., additional, Oriso, S., additional, Yoshiyama, M., additional, Kakinoki, S., additional, Nishioka, T., additional, Ozaki, T., additional, Nomoto, K., additional, Seki, K., additional, Kawai, K., additional, Ozaki, Y., additional, Miura, S., additional, Kawasaki, M., additional, Funada, R., additional, Dote, K., additional, Nagano, T., additional, Okamoto, S., additional, Kubo, T., additional, Murozono, Y., additional, Owada, T., additional, Doke, T., additional, Matsumura, T., additional, Horiuchi, M., additional, Takaishi, A., additional, Yamamoto, M., additional, Nakashima, H., additional, Munemasa, M., additional, Sakata, Y., additional, Inoue, N., additional, Ota, T., additional, Hamano, Y., additional, Abe, N., additional, Tsubokura, T., additional, Goto, M., additional, Kubota, I., additional, Yano, M., additional, Umetani, K., additional, Date, T., additional, Morimoto, H., additional, Noda, T., additional, Goto, S., additional, Hibi, K., additional, Nakano, A., additional, Hiramitsu, S., additional, Kihara, Y., additional, Sugi, M., additional, Shiba, N., additional, Izumi, D., additional, Sato, T., additional, Tayama, S., additional, Matsui, T., additional, Suzuki, A., additional, Ajiki, K., additional, Oishi, M., additional, Kiryu, M., additional, Ko, T., additional, Ando, H., additional, Miyazaki, S., additional, Kinugawa, T., additional, Otake, H., additional, Kitaoka, H., additional, Hirata, Y., additional, Honda, S., additional, Manita, M., additional, Ishii, Y., additional, Oka, H., additional, Nanba, Y., additional, Nishino, M., additional, Sakamoto, T., additional, Saito, T., additional, Sakai, H., additional, Ichikawa, M., additional, Namiuchi, S., additional, Inoue, K., additional, Komiyama, N., additional, Akashi, Y., additional, Nakamura, Y., additional, Komaru, T., additional, Hosokawa, T., additional, Chikamori, T., additional, Tanaka, H., additional, Arasaki, O., additional, Aonuma, K., additional, Wakasa, Y., additional, Yoshizawa, T., additional, Sugano, T., additional, Yokota, N., additional, Kakutani, A., additional, Suzuki, T., additional, Abe, Y., additional, Kataoka, T., additional, Okayama, H., additional, Yokoi, H., additional, Chin, K., additional, Hasegawa, K., additional, Tomita, H., additional, Honzyo, H., additional, Kawai, H., additional, Yamamoto, K., additional, Morino, Y., additional, Tsujiyama, S., additional, Hamasaki, S., additional, Niijima, Y., additional, Mizuno, Y., additional, Maki, A., additional, Tanabe, K., additional, Murohara, T., additional, Naomi, S., additional, Arikawa, M., additional, Kato, T., additional, Matsumoto, N., additional, Minamino, T., additional, Sairenji, H., additional, Miyamoto, N., additional, Ito, H., additional, Matsuura, Y., additional, Hata, S., additional, Nakatsu, Y., additional, Onodera, T., additional, Yoshimura, M., additional, Amano, H., additional, Tokutake, E., additional, Kasao, M., additional, Moriguchi, M., additional, Tsuji, M., additional, Yamamoto, H., additional, Yanbe, Y., additional, Iwasawa, T., additional, Suzuki, M., additional, and Mori, H., additional

Published
2021
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