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294 results on '"Tsuchie, Hiroyuki"'

1. Coefficient of variation of T2-weighted MRI may predict the prognosis of malignant peripheral nerve sheath tumor

Author

Emori, Makoto, Tsuchie, Hiroyuki, Takashima, Hiroyuki, Teramoto, Atsushi, Murahashi, Yasutaka, Imura, Yoshinori, Outani, Hidetatsu, Nakai, Sho, Takenaka, Satoshi, Hirota, Ryosuke, Nakahashi, Naoya, Shimizu, Junya, Murase, Kazuyuki, Takasawa, Akira, Nagasawa, Hiroyuki, Sugita, Shintaro, Takada, Kohichi, Hasegawa, Tadashi, Okada, Seiji, Miyakoshi, Naohisa, and Yamashita, Toshihiko

Published
2024
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11. Evaluation of factors affecting the occurrence of second atypical fracture after bone union of the first atypical fracture

Author

Tsuchie, Hiroyuki, Miyakoshi, Naohisa, Kasukawa, Yuji, Nozaka, Koji, Saito, Kimio, Kinoshita, Hayato, Kobatyashi, Moto, Suzuki, Norio, Aizawa, Toshiaki, Abe, Hidekazu, Maekawa, Shigeto, Tomite, Takanori, Ono, Yuichi, Ouchi, Kentaro, Shibata, Nobusuke, Nagahata, Itsuki, Takeshima, Masaaki, Akagawa, Manabu, Yuasa, Yusuke, Sato, Chie, and Shimada, Yoichi

Published
2021
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13. Factors Affecting the Second Complete Atypical Femoral Fracture after the First Atypical Fracture

Author

Tsuchie, Hiroyuki, primary, Kasukawa, Yuji, additional, Nozaka, Koji, additional, Kinoshita, Hayato, additional, Sasaki, Ken, additional, Aizawa, Toshiaki, additional, Mita, Motoki, additional, Ouchi, Kentaro, additional, Yuasa, Yusuke, additional, Miura, Takanori, additional, Tomite, Takenori, additional, Maekawa, Shigeto, additional, Abe, Hidekazu, additional, Akagawa, Manabu, additional, Shibata, Nobusuke, additional, Fujii, Masashi, additional, Takeshima, Masaaki, additional, Inoue, Jyunichi, additional, Saito, Hikaru, additional, and Miyakoshi, Naohisa, additional

Published
2023
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18. Factors Affecting the Second Complete Atypical Femoral Fracture after the First Atypical Fracture.

Author

Tsuchie, Hiroyuki, Kasukawa, Yuji, Nozaka, Koji, Kinoshita, Hayato, Sasaki, Ken, Aizawa, Toshiaki, Mita, Motoki, Ouchi, Kentaro, Yuasa, Yusuke, Miura, Takanori, Tomite, Takenori, Maekawa, Shigeto, Abe, Hidekazu, Akagawa, Manabu, Shibata, Nobusuke, Fujii, Masashi, Takeshima, Masaaki, Inoue, Jyunichi, Saito, Hikaru, and Miyakoshi, Naohisa

Subjects
*FEMORAL fractures, *COMPACT bone, *FEMUR, *BONE shafts, *HIP fractures
Abstract

Objectives: Atypical femoral fracture (AFF) is an atypical low-energy subtrochanteric and diaphyseal femoral fracture. Even if bone fusion is achieved in patients with AFF, the risk of AFF in the contralateral femur must be considered. This study aimed to investigate the factors affecting complete AFF in the contralateral femur and conservatively treated incomplete AFF. Subject and Methods: Radiographs of 111 femurs in 104 AFF cases were examined, and the femurs were classified as follows: 85 contralateral femurs with complete AFF; 18 contralateral femurs with incomplete AFF; 8 femurs with incomplete AFF without surgical treatment. Various patients' clinical data were collected, and we investigated the factors affecting the second complete AFF. Results: Complete fractures occurred in 10 (9.7%) of 103 femurs without incomplete AFF at the first visit and in 3 (37.5%) of 8 femurs with incomplete AFF. The Kaplan-Meier curve revealed that lateral cortical bone thickening and thigh pain were associated with significantly poorer prognoses (p = 0.026 and p = 0.013, respectively). Multivariate analyses revealed that eldecalcitol usage after AFF onset (p = 0.0094) and previous use of bisphosphonate or denosumab (p = 0.0126) were protective factors for second complete AFF and that the presence of thigh pain (p = 0.0134) was a risk factor for second complete AFF. Conclusions: Eldecalcitol administration after bone union of first AFF may prevent AFF recurrence. In addition, painful incomplete AFF has a high risk of developing a complete fracture. [ABSTRACT FROM AUTHOR]

Published
2024
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20. Coefficient of variation of T2-weighted MRI may predict the prognosis of malignant peripheral nerve sheath tumor

Author

Emori, Makoto, primary, Tsuchie, Hiroyuki, additional, Takashima, Hiroyuki, additional, Teramoto, Atsushi, additional, Murahashi, Yasutaka, additional, Imura, Yoshinori, additional, Outani, Hidetatsu, additional, Nakai, Sho, additional, Takenaka, Satoshi, additional, Hirota, Ryosuke, additional, Nakahashi, Naoya, additional, Shimizu, Junya, additional, Murase, Kazuyuki, additional, Takasawa, Akira, additional, Nagasawa, Hiroyuki, additional, Sugita, Shintaro, additional, Takada, Kohichi, additional, Hasegawa, Tadashi, additional, Okada, Seiji, additional, Miyakoshi, Naohisa, additional, and Yamashita, Toshihiko, additional

Published
2023
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23. Effects of activated vitamin D, alfacalcidol, and low-intensity aerobic exercise on osteopenia and muscle atrophy in type 2 diabetes mellitus model rats

Author

Akagawa, Manabu, Miyakoshi, Naohisa, Kasukawa, Yuji, Ono, Yuichi, Yuasa, Yusuke, Nagahata, Itsuki, Sato, Chiaki, Tsuchie, Hiroyuki, Nagasawa, Hiroyuki, Hongo, Michio, Shimada, Yoichi, Akagawa, Manabu, Miyakoshi, Naohisa, Kasukawa, Yuji, Ono, Yuichi, Yuasa, Yusuke, Nagahata, Itsuki, Sato, Chiaki, Tsuchie, Hiroyuki, Nagasawa, Hiroyuki, Hongo, Michio, and Shimada, Yoichi

Abstract

Diabetes mellitus causes secondary osteoporosis and muscle atrophy. The ability of alfacalcidol (ALF) and exercise (Exe) to inhibit osteoporosis and muscle atrophy in type 2 diabetes mellitus (T2DM) model rats was examined. Twenty-week-old Otsuka Long-Evans Tokushima Fatty rats were randomized to ALF (orally 0.1 mu g/kg/day), Exe (treadmill exercise at 10 m/min, 60 min/day, 5 days/week), Comb (ALF and Exe), and Cont (T2DM control treated with vehicle and no exercise) groups (n = 8-10 per group). Sedentary Long-Evans Tokushima Otsuka rats were used as a non-hyperphagic control. After treatment for 2 or 6 weeks, blood glucose (BG) levels, cross-sectional area (CSA) of tibialis anterior muscle fibers, femoral bone mineral density (BMD), and relative quantities of muscle anabolic markers (Pax7, MyoD, and myogenin) and catabolic markers (Atrogin-1, MuRF1, and REDD1) of the soleus muscle assessed by real-time polymerase chain reaction assays were measured. Exe and Comb treatments for 6 weeks decreased BG levels compared with those of the Cont group. ALF, Exe, and Comb treatments for 2 and 6 weeks recovered the CSA compared with that of the Cont group. ALF and Comb treatments for 6 weeks increased femoral BMDs compared with those of the Cont group. After 2 weeks of treatment, Comb treatment increased MyoD expression and decreased MuRF1 expression. ALF or Exe monotherapy significantly decreased Atrogin-1 or MuRF1 expression after 2 weeks of treatment, respectively. After 6 weeks of treatment, ALF and Comb treatments decreased Atrogin-1 and REDD1. These results demonstrate that a combination of ALF and Exe improved CSA from the early phase of treatment by stimulating skeletal muscle differentiation and suppressing muscle catabolic genes. Improvements in BG, BMD, and CSA were observed as long-term effects of the combination therapy. Continued suppression of muscle catabolic genes was observed as a background to these effects.

Published
2023

27. Successful Treatment of Atypical Femoral Fracture with Bowed Femur Using Contralateral Intramedullary Nail Combined with Early Daily Teriparatide

Author

Akagawa, Manabu, Miyakoshi, Naohisa, Tsuchie, Hiroyuki, Kasukawa, Yuji, Kawaragi, Takashi, Nagahata, Itsuki, Suzuki, Masazumi, Yoshikawa, Takayuki, Abe, Toshiki, and Shimada, Yoichi

Subjects
teriparatide, cephalomedullary screw, bowing deformity, atypical femoral fracture, intramedullary nail
Abstract

We report a case of atypical femoral fracture achieving early fracture union with combination therapy comprising contralateral nail and immediate teriparatide injection. Fracture union of atypical fractures is often delayed due to bowing deformity and bone metabolic disorders. Combination treatment that takes both problems into consideration represents a useful treatment option for atypical femoral fracture.

Published
2022

29. Effects of Soft Tissue Sarcoma and Doxorubicin on Bone Metabolism in Mice

Author

KASAMA, FUMIHITO, primary, TSUCHIE, HIROYUKI, additional, NAGASAWA, HIROYUKI, additional, HONGO, MICHIO, additional, KASUKAWA, YUJI, additional, NOZAKA, KOJI, additional, KUDO, DAISUKE, additional, SHOJI, RYO, additional, IGARASHI, SHUN, additional, HARATA, SHUNTARO, additional, OKAMOTO, KENTO, additional, OYA, KEITA, additional, and MIYAKOSHI, NAOHISA, additional

Published
2023
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33. Intravascular Administration of Acridine Orange and Zoledronate in a Bone Metastasis Model of Breast Cancer

Author

SHOJI, RYO, primary, TSUCHIE, HIROYUKI, additional, NAGASAWA, HIROYUKI, additional, HONGO, MICHIO, additional, KASUKAWA, YUJI, additional, NOZAKA, KOJI, additional, KUDO, DAISUKE, additional, SAITO, HIKARU, additional, ABE, KAZUNOBU, additional, IGARASHI, SHUN, additional, HARATA, SHUNTARO, additional, KASAMA, FUMIHITO, additional, and MIYAKOSHI, NAOHISA, additional

Published
2022
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39. Guideline-based Treatment of Glucocorticoid-induced Osteoporosis in Patients with Rheumatoid Arthritis: A Retrospective Study with the AORA Registry

Author

Kawano, Tetsuya, Miyakoshi, Naohisa, Tsuchie, Hiroyuki, Kashiwagura, Takeshi, Kobayashi, Moto, Aonuma, Hiroshi, Sugimura, Yusuke, and Shimada, Yoichi

Subjects
rheumatoid arthritis, Adult, Aged, 80 and over, Male, Bone Density Conservation Agents, glucocorticoid-induced osteoporosis, Middle Aged, Arthritis, Rheumatoid, osteopenia, Bone Density, Risk Factors, Humans, Osteoporosis, glucocorticoid, Female, Registries, Glucocorticoids, Aged, Retrospective Studies
Abstract

Glucocorticoid-induced osteoporosis (GIOP) is one of the side effects associated with glucocorticoid (GC) therapy. In 2014, the Japanese Society for Bone and Mineral Research (JSBMR) provided new guidelines for the management and treatment of GIOP. The aim of the present study was to clarify the prevalence of patients with rheumatoid arthritis (RA) requiring treatment according to the new guidelines and to identify risk factors associated with lack of treatment in these patients. Patients in the 2018 Akita Orthopedic group on Rheumatoid Arthritis (AORA) database were enrolled. Of 2,234 patients with RA in the database, 683 (30.6%) met the 2014 JSBMR guideline treatment criteria, and 480 (70.3%) had been treated. The untreated group included a larger number of males, younger patients, and patients treated in clinics rather than hospital (p

Published
2021

40. Deep Angiomyxoma of the Thigh That Is Difficult to Diagnose: A Case Report and Literature Review

Author

Tsuchie, Hiroyuki, Miyakoshi, Naohisa, Nagasawa, Hiroyuki, Nanjo, Hiroshi, and Shimada, Yoichi

Subjects
body regions, Adult, deep angiomyxoma, Anti-Inflammatory Agents, Non-Steroidal, desmoid-type fibromatosis, Humans, Female, ortho-Aminobenzoates, thigh, Meloxicam, Myxoma
Abstract

We present an extremely rare case of deep angiomyxoma (DAM) in the thigh that was misdiagnosed as desmoid-type fibromatosis. A 40-year-old Japanese woman presented with a mass on the left thigh. The histological diagnosis by needle biopsy was desmoid-type fibromatosis; the tumor grew slowly and was resected 4 years later. The histological diagnosis from the resected tumor was DAM. As of 16 months post-surgery, the patient has not noticed any local recurrence. Although DAM in a lower extremity is extremely rare, clinicians must be aware of its possible occurrence in areas relatively close to the pelvis.

Published
2021

41. Tumor Lysis Syndrome due to Eribulin Administration for Metastatic Undifferentiated Pleomorphic Sarcoma of the Buttock

Author

Tsuchie, Hiroyuki, Miyakoshi, Naohisa, Nagasawa, Hiroyuki, and Shimada, Yoichi

Subjects
Antineoplastic Agents, Sarcoma, Soft Tissue Neoplasms, Ketones, cancer chemotherapy, Fatal Outcome, soft tissue sarcoma, Positron Emission Tomography Computed Tomography, metastasis, Buttocks, Humans, Female, Furans, Tumor Lysis Syndrome, eribulin, Aged
Abstract

Tumor lysis syndrome (TLS) is a complication of cancer treatment that requires urgent intervention. It is extremely rare in the treatment of soft tissue sarcoma (STS) of the limbs or trunk, and there are currently no reports of TLS occurrence from eribulin therapy. We report the case of a 78-year-old woman with an undiffer-entiated pleomorphic sarcoma on the right buttock. We initiated chemotherapy with intravenous eribulin mesylate. Deterioration of renal function, mild hyperkalemia, hyperuricemia, hypocalcemia, and hyperphos-phatemia were confirmed on examination, suggesting the presence of TLS. We present an extremely rare case of TLS from eribulin for STS.

Published
2021

44. Evaluation of the nature and etiologies of risk factors for diaphyseal atypical femoral fractures

Author

Tsuchie, Hiroyuki, primary, Miyakoshi, Naohisa, additional, Kasukawa, Yuji, additional, Nozaka, Koji, additional, Saito, Kimio, additional, Kinoshita, Hayato, additional, Kobayashi, Moto, additional, Suzuki, Norio, additional, Aizawa, Toshiaki, additional, Abe, Hidekazu, additional, Maekawa, Shigeto, additional, Tomite, Takenori, additional, Ono, Yuichi, additional, Ouchi, Kentaro, additional, Shibata, Nobusuke, additional, Nagahata, Itsuki, additional, Takeshima, Masaaki, additional, Akagawa, Manabu, additional, Yuasa, Yusuke, additional, Sato, Chie, additional, and Shimada, Yoichi, additional

Published
2021
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45. Clinical Outcomes of Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma of the Extremities: Analysis of Recurrence Factors

Author

Zeniya, Toshiki, primary, Emori, Makoto, additional, Tsuchie, Hiroyuki, additional, Nagasawa, Hiroyuki, additional, Iba, Kousuke, additional, Mizushima, Emi, additional, Keira, Yoshiko, additional, Shimizu, Junya, additional, Murahashi, Yasutaka, additional, Teramoto, Atsushi, additional, Miyakoshi, Naohisa, additional, Sugita, Shintaro, additional, Hasegawa, Tadashi, additional, Shimada, Yoichi, additional, and Yamashita, Toshihiko, additional

Published
2021
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