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Basal thumb arthritis is a common condition with the earliest stage described as a period of ligament laxity and joint instability, without radiographic signs of arthritis. The condition is usually managed conservatively but a number of individuals can present with persistence of symptoms. We would like to describe our preferred technique for the management carpometacarpal ligament instability and laxity. This technique utilizes a slip of the flexor carpi radialis tendon and offers reconstruction of the intermetacarpal, dorsoradial and anterior oblique ligaments in an anatomic fashion using standard instruments available. The author has performed this technique in 33 patients over a course of 10 years and long-term outcomes of these cases are presented in this paper.

Background: The Pulvertaft weave was described more than 50 years ago and is still used in tendon transfers. The aim of this study was to evaluate the strength of a modified core suture Pulvertaft weave technique and compare it to the original Pulvertaft weave traditionally used in tendon transfer surgery. Methods: 12 extensor pollicis longus tendons and extensor indices proprius tendons were harvested from fresh frozen cadavers. Six Pulvertaft weaves were performed using FiberWire 4.0 and six core suture tendon weave were performed using FiberLoop 4.0. Biomechanical analysis was performed and stifness, first failure load and ultimate failure load were measured for both set of repairs. Results: The stiffness of the core suture tendon repair (9.5 N/mm) was greater than that of the Pulvertaft repair (2.5 N/mm) The first failure load of the core suture tendon repairs (68.9 N) was greater than the Pulvertaft repairs (19.2 N) and the ultimate failure load of the core suture tendon repairs (101.8 N) was greater than the Pulvertaft repairs (21.9 N). All of these differences were statistically significant. Conclusions: The core suture Pulvertaft weave is a modification to the Pulvertaft weave used in tendon transfers. The results of this cadaveric study suggest it is 5 times stronger than the traditional Pulvertaft repair, potentially allowing it to be used with early active motion protocols after tendon transfers.

Resumen El reimplante es la obra maestra del cirujano de mano, donde incluye la tecnica microquirurgica para la anastomosis de arteria, vena y reparacion del nervio, la osteosintesis de los huesos y el manejo de tejidos blandos como los tendones y la piel Indicaciones absolutas, amputacion del pulgar, el pulgar es quizas el elemento mas importante de la mano, dado que le da funcionalidad a la extremidad, sin importar la movilidad final ni la sensibilidad debe reimplantarse el pulgar. No se debe intentar el reimplante en lesiones aplastantes de los dedos, amputacion en mas de un nivel, presencia de lesiones que amenacen la vida del paciente, enfermedades graves del paciente, isquemia prolongada, amputaciones en paciente con alteraciones psiquiatricas. Clasificacion segun Tamai es la mas utilizada. Se explica ademas como se debe transportar la parte amputada. La tecnica microquirurgica es lo mas importante para el desenlace. La rehabilitacion fisica y posibles complicaciones. Nivel de Evidencia IV

Background: Since the Sauvé-Kapandji procedure was introduced in 1936, many modifications were created using dynamic stabilizer, such as the ECU (extensor carpi ulnaris), the FCU (flexor carpi ulnaris), pronator teres to solve proximal ulnar stump pain. We believe that this modification is also another option for distal ulnar stump instability. Methods: From January 1998 to February 2017, there were 13 patients received the Sauvé-Kapandji (S-K) procedure with tenodesis of the ECU to the carpus and interosseous membrane. The average age at operation was 52 years (range, 28 to 63 years). Four had traumatic arthritis (two from distal radial fracture malunion, two had instability of distal radioulnar joint from Essex-Lopresti injury), four had primary osteoarthritis of the distal radio-ulnar joint, two had rheumatoid arthritis, one had gouty arthritis, two had madelung deformity. The average follow-up was 30 months (range, 15 to 72 months). Results: Postoperative pronation/supination of the forearm had significantly improved with the exception of the wrist flexion/extension. After surgery, the mean radioulnar distance was narrowed from 11 mm to 9 mm, but no significant difference in 12 patients. All patients had improved in wrist pain, 10 patients had no pain and 3 patients with mild pain over the distal ulnar stump. The mean grip strength had significantly improved from 51% of the contralateral side to 75%. The lateral and stress X-ray films showed no instability of the distal ulnar stump after surgery. Conclusions: In conclusion, the modified S-K procedure using the tenodesis of ECU provides a multi-directional stability and is a reliable surgical procedure for distal radioulnar disorders.

Purpose: To assess the outcomes of double fascial flap stabilization in managing ulnar nerve subluxation after a simple decompression procedure for cubital tunnel syndrome. Methods: We conducted a retrospective review of 20 patients who experienced ulnar nerve subluxation after simple decompression and were treated with double fascial flap stabilization between 2016 and 2018. Fascial flaps were harvested from the flexor carpi ulnaris and the septum between the triceps and biceps. Patients were classified using McGowan criteria and outcomes were measured using the visual analog scale, grip strength, and the criteria of Messina and Messina for recovery. In addition, we assessed ulnar nerve instability after in situ decompression in 10 fresh cadavers. Tang’s grading and measuring system was used to measure ulnar instability. Results: There were 13 excellent and 7 good outcomes (65% and 35%, respectively). Mean follow-up duration was 9.1 months (range, 3–23 months). Mean visual analog scale scores improved significantly from 5.8 before to 1.3 after surgery. Mean Quick–Disabilities of the Arm, Shoulder, and Hand scores improved significantly from 37.9 before to 10.9 after surgery. Mean grip strength compared with the contralateral side improved significantly from 73.9% before to 89.6% after surgery. Anatomic cadaveric dissection revealed that 6 of 10 cadavers (60%) met the criterion of moderate to severe ulnar nerve instability. Conclusions: Double fascial flap stabilization with simple decompression resulted in excellent short-term clinical results. This technique provides an alternative strategy to prevent ulnar nerve instability with the advantage of preserving nerve vascularity. Long-term follow-up is required to evaluate the potential impact on recurrence or failure of simple decompression. Type of study/level of evidence: Therapeutic IV. Key words: anterior transposition, cubital tunnel syndrome, fascial flap, in situ decompression, ulnar nerve dislocation

Vascularized composite allotransplantation (VCA) has emerged as the most recent field of transplantation to offer an alternative treatment for those patients that have failed or are not suitable candidates for conventional therapy. Most of the current clinical experience in this field is with recipients of skin containing grafts such as the face, upper extremity and abdominal wall transplants. Like solid organ recipients, VCA recipients require lifelong systematic immunosuppression to maintain their grafts. To date, the most successful immunosuppressant regimens are calcineurin inhibitor based and have been targeted to the control of T cells. While these regimens have resulted in excellent short term graft survival in solid organ transplantation, achieving significant improvements in long term survival has been more challenging. The reasons are multi-factorial, but a role for B cells and humoral immunity has been proposed. Antibody mediated rejection leading to chronic rejection has been cited as the leading cause of renal graft loss. While the number of VCA transplants performed is still small, evidence to date suggests that antibody mediated rejection may occur less frequently than seen in solid organ transplants. Here we will discuss the role of B cell immunity in solid organ transplantation as it pertains and contrasts to the field of VCA and present some examples of possible sequela of B cell immunity in a series of hand transplant recipients.

Background The gold standard for nerve repair is end-to-end (ETE) repair. Helicoid technique (HT) has also been previously described. In this pilot study, HT was compared to ETE and a modified helicoid weave technique (MHWT). In MHWT, recipient nerve is passed through rather than around the donor nerve, allowing for greater nerve-to-nerve interaction. Methods Eighteen adult male Lewis rats received a 2-cm sciatic nerve transection and were divided into three groups: ETE, HT, and MHWT. Five months later, electromyography (EMG), tetanic force of contraction, and wet weight of the extensor digitorum longus muscle were recorded in both the operated and non-operated sides. Nerve biopsies were taken proximal and distal to the site of the nerve graft for histological examination. Results One rat died following repair surgery and three rats died during the second surgery. The mean threshold of stimulation for ETE, HT, and MHWT were 183.3 µA, 3707.5 µA, and 656.6 µA, respectively. EMG analysis revealed that latency and duration are both affected by surgical repair type and injured or uninjured conditions. Threshold ratio (injured:non-injured) revealed pilot-level significant differences between HT and both MHWT (p = 0.069) and ETE (p = 0.082). Nerve biopsy demonstrated fascicles distally in all three groups. Conclusions While HT and MHWT function as a nerve repair technique, they are not superior to ETE. ETE remains the gold standard for nerve repair. While mean values were in favor of ETE, no statistical significance was attained.

Mallet fingers are injuries to the extensor tendon at the distal interphalangeal (DIP) joint and can present as a bony avulsion or as a soft tissue injury. Nonbony mallet fingers are frequently splinted in extension between 6 and 8 weeks. If splinted correctly, most results are good with a mean DIP joint extension lag between 5 and 10 degrees. However, decreased swelling, hygienic considerations and patient compliance can lead to splint removal and a less favorable outcome. We present a percutaneous tenodermodesis using only a digital block and a 4.0 nylon suture. This office-based procedure provides joint reduction and prevents joint movement during the immobilization period. The suture can be removed after 8 weeks, allowing active mobilization of the DIP joint. We present the results of 8 patients with a mean follow-up of 3 months and mean initial extension lag of 32 degrees, resulting in a mean final extension lag of 2 degrees and excellent outcomes using the Crawford criteria.

Purpose The abductor digiti minimi (ADM) and flexor digiti minimi (FDM) muscles have a similar vascular and nerve supply . The purpose of this study was to assess the feasibility of transferring the FDM instead of ADM for thumb opposition. Methods Thirty cadaver hands were dissected under loupe magnification to assess the presence of the ADM and FDM muscles as well as their blood and nerve supply. The length of these muscles and their location in relation to the radial aspect of the thumb metacarpophalangeal joint were assessed. Results The ADM muscle was present in all cadavers whereas the FDM muscle was absent in 33% of hands. When the dimensions were suitable (53%), the more radially located FDM muscle reached the thumb metacarpophalangeal joint more easily. Conclusions Although the dissections revealed considerable variability in FDM anatomy, when present, it can have positional advantage over the ADM for opponensplasty. Clinical relevance In some cases with radial longitudinal deficiency, preservation of ADM function is essential. In these children, the FDM can potentially be explored and transferred if it is found to be suitable.

Backround: Brachial plexus injuries are complex cases requiring a thorough understanding of nerve physiology and upper extremity anatomy. Standard approaches and management have been developed but certain situations still arise where these are not feasible options. Objectives: A case of brachial plexus injury is discussed in this report. The patient was a young male who was referred to our center with weakness of the left upper extremity, C5-C7 distribution. Certain components of his injury, such as extensive soft tissue scarring and identification of a long neuroma at the injury site, obliged the surgeons to use unconventional nerve transfers during his surgery. In this paper, we discuss these alternative options in order to support their potential use in complex brachial plexus cases. Other concepts such as single fascicular harvest for nerve transfers and nerve graft augmented nerve transfers are discussed as they were successfully used in this report. Methodology and Results: The patient underwent a total of five surgeries which were a combination of nerve and tendon transfers. Some nerve transfers were augmented with long autologous nerve grafts reaching up to fifteen centimeters in length. Throughout the patients sequence of surgeries, certain nerves, such as the ulnar nerve branch to the flexor carpi ulnaris, successfully served as a donor nerve in more than one occasion. Muscle groups where single nerve fascicles were previously used as a donor nerves also yielded adequate muscle strength and were successfully subsequently used in tendon transfers. Ultimately, the patient was able to achieve good muscle strength, range of motion and outcome scores on his left upper extremity after two years from his final surgery. Conclusion: This report offers multiple alternative options in managing complex brachial plexus cases as well as challenges some concepts in nerve grafting. Alternative donor nerves are offered for transfers, some of which are not previously used in literature. Aside from this, the use of long autologous nerve grafts, single fascicular nerve transfers and repeated use of certain nerves as donor were performed successfully. We hope these procedures and techniques can be added to each hand specialist arsenal for managing complex brachial plexus injuries, specifically when the standard techniques are not feasible.

The pediatric patients and parents must have enough psychological preparations before considering adopting microsurgical techniques to repair hand congenital deformities. For the parents, their child has lost one hand or one pair of perfect hands; if they consider undergoing toe transplantation or using free flaps to repair the deformed hand, the pediatric patient will lose the complete toes or other histological structures, and new injuries will arise; in the meantime, the surgeons cannot guarantee that the microsurgery is bound to succeed; therefore, the parents always have many concerns and are under great pressure, which will unconsciously influence the surgeons; under this circumstance, many surgeons will passively select microsurgery. Therefore, for the surgeons, pediatric patients (if possible), and their parents, before the microsurgery, an in-depth discussion will be conducted on various conditions before the surgery, during the surgery, and after the surgery; the child’s family will be asked to make the final choice and the surgeons will respect this choice, which is very important.

The Louisville VCA (Vascularized Composite Allograft) Program is one of the largest hand transplant programs in the world. During my hand surgery fellowship at the Christine M. Kleinert Institute, the team performed the eighth hand transplant on the seventh recipient in Louisville. The Louisville VCA Program has done 9 hand transplants in 8 recipients with one bilateral case. Among these are the first 5 hand transplant cases in the United States. The first case was done in 1999 and has the World's longest follow-up. The seventh case was performed in a 36-year-old male on July 10, 2011. The result achieved so far can be considered excellent with a very good patient satisfaction. There is a large multidisciplinary team involved in such procedures with all members playing a crucial role for the achievement of the best result possible. The present paper focuses on the surgical procedure for the seventh recipient, which was unique due to the level of amputation of the recipient's hand, with preservation of nerve to the thumb.

ResumoO Programa de Enxerto Alográfico Vascularizado Composto (Vascularized Composite Allograft ou VCA Program) de Louisville é um dos maiores de transplante de mão no mundo. Durante o meu fellowship em cirurgia da mão no Christine M. Kleinert Institute, o grupo fez o oitavo transplante de mão no sétimo receptor em Louisville. O VCA Program de Louisville já fez nove transplantes de mão em oito receptores (um caso bilateral). Entre esses estão os primeiros cinco casos de transplante de mão nos Estados Unidos da América. O primeiro foi feito em 1999, o que teve o mais longo seguimento em todo o mundo. O sétimo caso foi feito em um paciente do sexo masculino de 36 anos em 10 de julho de 2011. O resultado obtido até agora pode ser considerado excelente, com ótimo benefício para o paciente. Em um procedimento como esse, existe uma grande equipe multidisciplinar envolvida, cada um tem uma função crucial para o alcance do melhor resultado possível. O presente artigo será focado no procedimento cirúrgico feito no sétimo receptor, que foi considerado um caso especial, por causa do nível da amputação da mão do paciente, com preservação do nervo para o polegar.AbstractThe Louisville VCA (Vascularized Composite Allograft) Program is one of the largest hand transplant programs in the world. During my hand surgery fellowship at the Christine M. Kleinert Institute, the team performed the eighth hand transplant on the seventh recipient in Louisville. The Louisville VCA Program has done 9 hand transplants in 8 recipients with one bilateral case. Among those are the first 5 hand transplant cases in the United States. The first case was done in 1999 and has the World's longest follow up. The seventh case was performed in a 36 years old male in July 10, 2011. The result achieved so far can be considered excellent with a very good patient satisfaction. There is a large multidisciplinary team that is involved in such procedure with all playing a crucial role for the achievement of the best result possible. The present paper will be focused on the surgical procedure for the seventh recipient, which was unique due to the level of amputation of the recipient's hand, with preservation of nerve to the thumb.

Various options exist for the surgical management of cubital tunnel syndrome. The goals of this study were to compare the outcome of four different surgical techniques: (1) simple decompression, (2) endoscopic decompression, (3) anterior subcutaneous transposition, and (4) anterior sub-muscular transposition for the treatment of cubital tunnel syndrome. One hundred ten patients (117 cases) with cubital tunnel syndrome were reviewed from 1986 to 2000. Parameters measured included signs and symptoms, medical comorbidity, other nerve compressions, and anatomical pathology. Severity was evaluated using the Dellon classification and the symptom severity score (SSS). SSS included evaluation of pain, clawing, the Froment sign, and the Wartenberg sign. Bishop's rating was measured at final follow-up. Statistical analysis included ANOVA, Kruskal–Wallis tests, and Spearman's Rho for correlation. Correlation between severity of nerve compression and symptom duration was not statistically significant. A significant weak positive correlation existed between Dellon score and SSS. Bishop's rating was 46.5 % excellent, 39.5 % good, 7.9 % fair, and 6.1 % poor overall. A significant weak negative correlation existed between the Dellon score and Bishop's rating. The average Bishop score was 1.74 ± 0.85, and no significant difference existed when comparing each surgical technique to one another. No significant association was found between the severity of compression (Dellon) and the surgery type performed. A weak negative correlation existed between severity of ulnar nerve compression and clinical outcome. No significant differences were found between the type of surgeries performed in regard to outcome and Dellon score. We found patients with the most severe compressive symptoms benefited the least from operative intervention regardless of surgical technique used. However, for mild to moderate disease, performing any of the purposed surgical techniques in accordance with the physician’s experience and comfort level is adequate in treating ulnar nerve compression at the elbow joint. Level of Evidence Level IV, therapeutic study

The problem of size discrepancy between vessels during microvascular procedures is well known. Inability to successfully overcome this problem can lead to turbulent flow at the anastomotic site with consequent thrombosis. Various techniques have been described to overcome this problem. We describe two techniques that have been used for over two decades in our institution. Both these techniques enable the surgeon to overcome far more significant size mismatches than other available techniques while still allowing for end-to-end anastomosis.

Crush avulsion injuries to the hand with concomitant traumatic amputation of multiple digits can be a devastating injury to the patient. These injuries have multiple issues occurring under emergency conditions. When feasible, replantation of the multiple digits is optimal, but in many cases, it is not possible. Because of the crushing force on the digits, they are not viable candidates for replantation. The usual course of treatment for these patients is a two stage procedure, usually involving a groin flap. Here, we present the case of a patient who had a left hand skin avulsion of the whole palm and P1 of index, long, ring and small fingers. The left index finger had a complete amputation at the P2 level, the long, ring and small fingers all had complete amputations at the P1 level. This injury was dealt with by a left foot second and third toe transplant, a sensory free flap from the left big toe and a fourth toe microvascular free transfer to the left hand. The remainder of the defect was managed with a 10 × 14 cm reversed radial forearm flap and a combination of full and split thickness skin grafts. The procedure was performed in a single operation, obviating the need for a second surgery. This procedure optimized the patient's outcome during a single setting, making it an ideal choice in an emergency setting.

Purpose The purpose of this study was to retrospectively review the results of 87 toe-to-hand transfers performed in 73 procedures, compare them to the report published by the senior author in 1983, and confirm the hypothesis that results of toe-to-hand transfers at our center have improved over time. Methods The results of 87 toe-to-hand transfers performed between 1981 and 2001 were reviewed and compared with the results of 54 toe-to-hand transfers performed between 1974 and 1980. The measured parameters were type of reconstruction performed, anticoagulation therapy, vascular patency, frequency of secondary surgery, and strength of thumb reconstructions. Results In the recent time period, 11% of the procedures had complications with revascularization of the transferred digit, and long-term survival was seen in 98% of the toe-to-hand transfers. This is a significant improvement over earlier results, in which 33% of the cases had some microvascular compromise and the survival of grafts was lower (91%). Pinch strength for thumb reconstructions improved, and the number of secondary surgeries performed dropped, but neither of these parameters reached a significant level. Toes used for reconstruction changed, with an 18% decrease in use of big toe for thumb reconstruction and a similar increase in use of the second toe. For non-thumb digital reconstructions there was a 60% decrease in use of second and third toe combined, whereas use of the second toe alone increased similarly. Conclusions This study showed reduction of the incidence of vascular compromise compared to the previous report. Improved strength of thumb reconstructions and reduced need for secondary surgery was also displayed. These findings are likely attributed to refinements in reconstructive procedures and operative techniques. Type of study/level of evidence Therapeutic IV.

The medial longitudinal arch of the foot plays a major role for a physiologic transfer of the load from the heel to the forefoot during walking and running. Traumatic amputation that involve either the great toe or the whole first metatarsal bone can lead to collapse of the medial longitudinal arch, overload of the metatarsal heads, and painful callus formation. If replant of the amputated part is not possible or has failed, it is advisable to reconstruct the medial longitudinal arch in order to re-establish a functional transfer of the load in the foot. We present a case of a young lady who suffered from traumatic amputation at the distal third of the first metatarsal. Replantation failed due to the severity of the initial injury. Despite a good coverage of the defect with a lateral arm flap, the patient developed a painful plantar callus underneath the amputated stump. The adjacent second metatarsal ray was then raised as a pedicled flap including bone and soft tissues and transferred to the first ray in order to reconstruct a physiologic medial longitudinal arch. The patient had excellent functional results with no recurrence of the callus.

The purpose of this study is to describe the harvesting technique, anatomic variations, and clinical applications of a compound flap from the great toe and vascularized joint from the second toe used for thumb reconstruction. Five fresh cadaver dissections were studied, focusing attention on the dorsal or plantar vascular dominance, position of the communicating branch between the dorsal and plantar system, the Gilbert classification, and the size of the first dorsal metatarsal artery (FDMA) and first plantar metatarsal artery (FPMA) to the great toe and second toe. Five compound flaps were performed on five patients with traumatic thumb amputation at the level of proximal metacarpal bone. The patients' ages ranged from 14 to 47. Follow-up period was 11-24 months. The anatomic study showed that FPMA had larger caliber in 40% of dissections, FDMA in 40%, and had the same caliber in 20%. The Gilbert classification of FDMA was 40% class I and 60% class III. In the clinical applications, four patients achieved good functional opposition and motion of transferred joints with good pinch and grip strength. There was one flap failure, and donor-site morbidity was minimal. The compound flap offers advantages over traditional toe transfer by providing two functional joints. It can be used for amputation of the thumb at carpometacarpal joint level. Finally, the compound flap maintains growth potential in children through transfer of vascularized epiphyses. The disadvantages of this compound flap include a technically challenging harvest and a longer operative time.

The techniques of reconstructive transplantation are based on the experience of microsurgeons, orthopedic surgeons, and plastic surgeons in the field of replantation and plastic reconstructive surgery. Our center has focused on the transplantation of the hand and forearm. Our approach to hand transplantation has evolved over the past 15 years, based on decades of replantation experience at our center and the types of patients and outcomes we have encountered. While a transplant is much like a replant, there are clear differences. First, unlike a replant, the length and availability of recipient muscles, tendons, vessels, and nerves are often shorter than suggested by the level of amputation. Second, while the donor allograft supplies more than adequate amounts of tissue, this may not match the recipient and care must be taken to match bony length, and attach tendons with the proper tension of flexors and extensors in order to optimize good function post transplant. Finally, the challenges of allograft rejection and the currently required systemic immunosuppression mandate close monitoring by a multidisciplinary team for the life of the graft. This chapter highlights the experience of the nine transplants performed in eight recipients, and the most important clinical considerations for good outcome in a vascularized composite allotransplantation (VCA) hand recipient.

Plaster of Paris has been largely superceded for casting in orthopedic departments by synthetic cast materials. Despite its weight, its relative brittleness, its unpopularity with patients, and its messiness in application, plaster of Paris remains the mainstay of casting in the emergency department. This is due to a combination of economic reasons, the belief that synthetic casts leave less room for swelling and its relative ease of application compared to synthetic materials. We present a technique for synthetic cast application that avoids the problems of the rapidly setting cast and therefore allows the time for less experienced hands to produce a well-fitting cast or splint. We believe that this option, which allows the patient to have a lighter synthetic cast, rather than the traditional plaster of Paris cast, will be welcomed by both the patient and physician.

Purpose: The purposes of this study were to determine the distribution of causes and sites of nerve compression in the ulnar tunnel (Guyon's canal), and investigate the relationship between ulnar tunnel syndrome (UTS) and other conditions associated with it. Methods: We performed a retrospective review of 31 patients diagnosed with and treated for UTS to determine the most common cause of compression and the sites of compression, systemic illnesses associated with UTS, and postoperative results. Results: The cause of ulnar nerve compression was idiopathic in 14, trauma in 8, a thrombosis in 2, proliferation of synovium in 2, a prominent hook of the hamate in 1, a schwannoma in 1, postoperative swelling in 1, an aberrant fibrous band in 1, and a ganglion in 1. The sites of compression were classified into 3 zones. Twenty-eight cases had compression in zone 1, 6 in zone 2, and 19 in zone 3. Seventeen cases (55%) had compression in more than 1 zone. Twenty-two cases (71%) were associated with carpal tunnel syndrome (CTS). Twelve (86%) of the 14 idiopathic UTS cases were associated with CTS. The relationship between idiopathic UTS and CTS was not statistically significant. Six cases were associated with diabetes mellitus. Conclusions: The most common cause of UTS in our series was idiopathic. Most idiopathic UTS cases were associated with CTS. The clinical symptoms of UTS improved after surgery in all cases. Therefore because of the presence of multiple compression sites of the ulnar nerve in the hand, for UTS patients we believe that the release of Guyon's canal and/or the pisohamate tunnel is an effective way not only to relieve symptoms but also to determine the real cause of compression.

Entrapment of the ulnar nerve that leads to cubital tunnel syndrome is a common and often disabling disease. Current surgical treatment options involve simple decompression, medial epicondylectomy, or a variety of anterior transposition procedures. Such techniques often involve extensive exposure of the ulnar nerve with prolonged periods of immobilization. Because of this, patients may often experience significant postoperative pain, scarring, and joint stiffness. In this paper, we describe a minimally invasive technique for treating cubital tunnel syndrome using endoscopic assistance. This procedure enables complete ulnar nerve decompression through one small incision. Direct visualization of all potential anatomic compression sites for a distance of 20 cm around the medial epicondyle is possible. This endoscopic approach to cubital tunnel release is appealing, especially to those patients with mild to moderate symptoms who may otherwise be reluctant to undergo a more involved conventional surgery. It decreases postoperative pain, reduces scarring, and promotes an earlier return to activity than traditional open techniques allow, due to a decreased immobilization period.

We compared carpal tunnel release using a radial sided approach (RCTR) with a two-incision approach with regards to complications, grip strength, and functional outcomes. Retrospective chart review was done and data was collected pre-operatively, and post-operatively at six weeks and three months. A total of 32 and 26 patients were included in the two-incision and RCTR groups respectively. At six weeks, the RCTR group showed an increased grip strength (+32.24%) while the two-incision group was weaker (-6.75%). Both groups showed an increased strength at three months, RCTR at 98.4% while the two-incision group was significantly lower at 38.6% increase. Both techniques provided improvement in outcome scores, with no statistical difference. RCTR was associated with a significantly earlier return of grip strength and had better grip strength at six weeks and three months post-operatively. Both techniques provided symptom relief and good functional outcome.

Major amputations remain a challenge to the replantation surgeon. Proper patient selection, good surgical skills, and cooperation among the patient, surgeon, and rehabilitation team help achieve a better outcome.

Background. The purpose of the present study was to determine if platelet-activating factor is an important mediator that produces vasospasm during reperfusion after ischemia in skeletal muscle. Materials and Methods. A vascular isolated cremaster muscle in male Sprague–Dawley rats was coupled with local intraarterial drug infusion as a model to study microcirculation responses to ischemia/reperfusion injury. Arteriole diameters and capillary perfusion were measured using intravital microscopy. Group 1: platelet-activating factor dose response. Group 2: Effects of a cyclooxygenase inhibitor; indomethacin, and a thromboxane synthetase inhibitor, imidazole, on the response to platelet-activating factor. Group 3: Effects of nitric oxide synthesis inhibitor; N ω -nitro- l -arginine methyl ester, on the response to platelet-activating factor. Group 4: Effects of a platelet-activating factor receptor antagonist, CV-3988, indomethacin, and imidazole after 4 h of warm ischemia and reperfusion. Results. Intraarterial infusion of platelet-activating factor produced a dose-related but mild vasoconstriction. Pretreatment with indomethacin or imidazole resulted in significant vasodilation actually emanating from platelet-activating factor infusion. Nitric oxide inhibition (with N ω -nitro- l -arginine methyl ester) enhanced the vasoconstriction produced by platelet-activating factor. Pretreatment with CV-3988, indomethacin, or imidazole significantly attenuated ischemia/reperfusion-induced vasospasm and capillary no-reflow in the cremaster muscles. Conclusions. Ischemia/reperfusion-induced vasoconstriction is at least in part mediated by platelet-activating factor and thromboxane A 2 .

The authors hypothesized that nitric oxide is induced by a brief period of ischemia/reperfusion (ischemic preconditioning, IPC) on postoperative day (POD) 1, and that this released nitric oxide is responsible for initiating a delayed microvascular protection against a prolonged period of ischemia in skeletal muscle on POD day 2. The cremaster muscle of male Sprague-Dawley rats underwent 4 hr of ischemia, and then 60 min of reperfusion. IPC consisted of 45 min of ischemia but was done 24 hr before the prolonged ischemia. Local intraarterial infusion of sodium nitroprusside (SNP, a donor of nitric oxide) or Nw-nitro-L-arginine (L-NA, a nonselective nitric oxide synthase antagonist) were also given 24 hr before prolonged ischemia. Arteriole diameters and capillary perfusion were measured using intravital microscopy. Four groups were compared: 1) control; 2) IPC; 3) SNP + sham IPC; and 4) L-NA + IPC. Four hours of ischemia followed by reperfusion created a significant vasoconstriction and capillary no-reflow in the microcirculation of cremaster muscles. These alterations were largely prevented by IPC. Local intraarterial infusion of SNP without IPC created a similar microvascular protection to that induced by IPC alone. In contrast, intraarterial infusion of L-NA prior to IPC eliminated the IPC-induced microvascular protection. In conclusion, in late preconditioning, nitric oxide contributes to the initiation of a delayed microvascular protection against prolonged ischemia in skeletal muscle.

The human hand is a supremely adaptable organ of prehension, sensation, expression, and communication. With its complex, integrated structures of skin, muscles, tendons, nerves, vessels, bones, and joints, the hand allows people to explore their environment, care for themselves, and earn a living. To watch a virtuoso pianist at work is to appreciate fully how the hand is capable of performing highly coordinated actions. The hand is so important as a tool and as a sensory organ that it could be claimed that the primary function of the upper extremity is to position the hand in space. Injuries of the upper extremity thus have a direct bearing on the function, sensation, and movement of the hand. The upper extremity, our interface with the external world, is subjected to the forces of the world and is easily injured. Such injuries—industrial, agricultural, domestic, or vehicular—disrupt the fine, intricately balanced anatomy of the structurally complex and functionally adaptable hand and can devastate the life and livelihood of the injured person. For many patients, such as laborers, musicians, carpenters, surgeons, and dentists, loss of hand function means loss of a career. However, advances in the pathophysiology of tissue trauma, microsurgery, antibiotics, and bone and tendon fixation techniques have enabled reconstructive surgeons to achieve better outcomes that maximize function and minimize disability for patients who have a severe injury of the upper extremity41. In this article, we present our concept of immediate comprehensive treatment of such injuries. Our discussion includes assessment of the patient, classification of injuries, provisional preoperative planning, wound excision, definitive decision-making, structural repair techniques, soft-tissue coverage, operative innovation and imagination in reconstruction, rehabilitation, and determinants of outcome. The first step in the treatment of an injury of the upper extremity is the assessment of the patient's condition—that is, the extent, …

We evaluated the results of cubital tunnel release with endoscopic assistance. The study included 76 patients (85 elbows); 47 women and 29 men. Nine patients had bilateral procedures. Patients were excluded if they had less than 1 year of follow-up, associated pathology at the elbow to account for the nerve compression, or recurrent cubital tunnel syndrome. Before surgery, cases were categorized by stage of cubital tunnel syndrome according to Dellon's classification: 33 (39%) elbows were classified as mild, 35 (41%) moderate, and 17 (20%) severe. Surgical results were assessed according to a modified Bishop rating system. The mean follow-up period was 32 months (range, 12-52 months). Results were excellent in 42% of the elbows, good in 45%, fair in 11%, and poor in 2%. Recurrence occurred in 3 elbows. There were no serious complications. The results of this study support our recommendation of cubital tunnel release with endoscopic assistance as a safe and reliable technique for the treatment of cubital tunnel syndrome, especially in patients with mild to moderate symptoms.

The anterior interosseous nerve syndrome was first described in 1948. It comprises less than 1% of all upper extremity nerve palsies. Patients have a characteristic pinch deformity, with paralysis or weakness of the muscles innervated by the anterior interosseous nerve, flexor pollicis longus, radial portion of the flexor digitorum profundus, and pronator quadratus. Electromyograms are positive in most patients presenting with motor complaints. Treatment is related to the specific etiology. Conservative treatment includes avoidance of strenuous forearm work, immobilization, steroid injections, and anti-inflammatory medications. If the presentation suggests nerve compression, and the EMG reveals evidence of axonal interruption, then surgical decompression should be performed. We present a series of six patients seen over a 7-year period. Improvement was noted in all the patients postoperatively.

INTRODUCTION The fingertips are critical to the prehensile function of the hand and allow humans to interact with the surrounding environment. The skin of the pulp is highly specialized, with unique cutaneous sensibility and special biomeachanical properties that are essential for precision manipulation and grasp. Fingertip injuries constitute one of the most common traumatic injuries, affecting one million people per year in the United States. Loss of or injury to this highly specialized skin can lead to significant dysfunction and long-term morbidity. Adverse sequelae of fingertip injuries include persistent pain, neuroma, dysesthesia, tenderness, narrowness and tightness of the tip, and cold intolerance. A variety of nail deformities may develop as a result of the loss of nail support, such as the hook or claw nail deformity. The resulting aesthetic deformity of the nail and the pulp can have a profound socioeconomic impact in some societies. The reconstructive goals in the management of fingertip injuries are to maintain length, sensibility, and joint function and to provide adequate support for the nail matrix. The final result of reconstruction should be a warm, sensate, well-padded, non-tender fingertip with a good cosmetic appearance. These goals should be achieved in a timely fashion to avoid prolonged immobilization and the associated functional and economic implications for the patient. Although a general consensus has been reached regarding the goals of fingertip injury treatment, opinions strongly differ as to the best method to achieve these goals. Options for wound management range from healing by secondary intention to microvascular toe pulp transfer. The most appropriate method of wound closure for a particular fingertip injury depends upon several factors. The type and extent of injury should be carefully evaluated prior to treatment. Other considerations include the patient's age, occupation, hand dominance, hobbies, and medical and smoking history. The surgeon's experience, complexity of the repair or reconstruction, and expected complications are all factored into the treatment choice. When coverage of a defect is required, local skin flaps are the most desirable choice, since they are similar in character to the lost skin. Local skin flaps are tissue flaps located immediately adjacent to the soft tissue defect. Local flaps are distinguished by the geometric principles employed to move the flap into the defect. They include advancement flaps, transposition flaps, rotation flaps, and island flaps. These flaps can be subdivided into axials flaps, random flaps, and neurovascular island flaps, based on the nature of the blood supply to the flap. The availability of local flaps in the hand is limited. The use of local flaps for fingertip reconstruction requires a precise understanding of the anatomy of the finger pulp and the selected flap. Flatt has pointed out that although local flaps of the hand appear to be of a simple nature, experience and judgment are required to employ them successfully.

This study examined the anatomic structures that communicate between the tibial and fibular digital arteries of the second toe at the distal phalanx to identify a channel for retrograde blood flow from the dominant pedicle to the distal joint flap. We also assessed the feasibility of two models designed to mobilize toe joints to perform single pedicle vascularized double-joint transfer. The continuity of the vascular pathway in both models was demonstrated by microfil injection and angiographic study. The average mobile distance between the PIP joint and the MTP joint was 5.6 +/- 0.6 cm in model I and 5.1 +/- 0.4 cm in model II. The dissection and mobilizing procedures of the neurovascular pedicle are more complicated and extensive in model II than in model I, and the risk of jeopardizing vascularity of the distal joint flap is higher. Both models may be suitable to replace two adjacent metacarpophalangeal (MCP) joints in the hand or two nonadjacent MCP joints (excluding the thumb) separated by no more than one normal metacarpal.

Ulnar neuropathy at or distal to the wrist, the so-called ulnar tunnel syndrome, is an uncommon but well-described condition. However, diagnosis of ulnar tunnel syndrome can be difficult. Paresthesias may be nonspecific or related to coexisting pathologies, such as carpal tunnel syndrome, cubital tunnel syndrome, thoracic outlet syndrome, C8–T1 radiculopathy, or peripheral neuropathy, which makes accurate diagnosis challenging. The advances in electrodiagnosis, ultrasonography, computed tomography, and magnetic resonance imaging have improved the diagnostic accuracy. This article offers an updated view of ulnar tunnel syndrome as well as its etiologies, diagnoses, and treatments.

Eight vascularized fibula grafts and two vascularized rib grafts were used for the treatment of 10 Boyd's Type II congenital pseudarthrosis of the tibia. All but one vascularized fibula graft united within 4 months. The two vascularized rib grafts did not unite until receiving a conventional bone graft. Nine spontaneous fractures were seen in four patients; all were subsequently treated successfully with cast or conventional bone graft. Corrective osteotomies were done in two patients. Follow-up averaged 8 years and 5 months (range, 5 years and 1 month to 14 years and 4 months). Average age at end of follow-up was 13 years and 6 months (range, 7 years and 10 months to 20 years and 4 months). After bony union was achieved, shortening of the affected leg averaged 3.8 centimeters, flexion deformity averaged 20 degrees, and valgus deformity averaged 24 degrees. In three patients, whose leg discrepancy averaged 4.9 centimeters, the leg was lengthened at an average patient age of 13 years and 9 months (age range, 11 years and 7 months to 15 years and 2 months). The resulting limb length discrepancy averaged 2.2 centimeters. Vascularized bone grafting is a reliable technique for achieving bony union in congenital pseudarthrosis of the tibia. Residual shortening may be corrected later by limb lengthening.

Introduction: The purpose of this study was to compare the result of treatment of patients with failed primary carpal tunnel surgery who suspected pronator teres syndrome (PTS) by performing revision carpal tunnel release (CTR) with pronator teres release (PTR) and revision CTR alone. Methods: Retrospective chart review in patients who required revision CTR and suspected PTS. Group 1, treated by redo CTR with PTR and group 2, treated by redo CTR alone. Intraoperative findings, pre and postoperative numbness (2-PD), pain (VAS score), and grip strength were studied. Results: There were 17 patients (20 wrists) in group 1 and 5 patients (5 wrists) in group 2. Patients in group 1 showed more chance of fully recovery of numbness and pain than group 2 (60% vs. 0%, p

Allogeneic hand transplantation is now a clinical reality. While results have been encouraging, acute rejection rates are higher than in their solid-organ counterparts. In contrast, chronic rejections, as defined by vasculopathy and/or fibrosis and atrophy of skin and other tissues, as well as antibody mediated rejection, have not been reported in a compliant hand transplant recipient. Monitoring vascularized composite allograft (VCA) hand recipients for rejection has routinely involved punch skin biopsies, vascular imaging and graft appearance. Our program, which has transplanted a total of 6 hand recipients, has experience which challenges these precepts. We present evidence that the vessels, both arteries and veins may also be a primary target of rejection in the hand. Two of our recipients developed severe intimal hyperplasia and vasculopathy early post-transplant. An analysis of events and our four other patients has shown that the standard techniques used for surveillance of rejection (i.e. punch skin biopsies, DSA and conventional vascular imaging studies) are inadequate for detecting the early stages of vasculopathy. In response, we have initiated studies using ultrasound biomicroscopy (UBM) to evaluate the vessel wall thickness. These findings suggest that vasculopathy should be a focus of frequent monitoring in VCA of the hand.

When a child sustains an amputated part it is a devastating injury for the child, his/her family, and the healthcare providers involved in the child’s care. This chapter will focus on recognizing the mechanisms of injury to aid in ­prevention, handling of the amputated part, and indications for replantation. A brief ­discussion of the operative technique, postoperative care, and outcomes will also be provided.