218 results on '"Tsoi, L.C."'
Search Results
2. 897 HERC6 is an Interferon induced E3 ubiquitin ligase that negatively regulates sex-specific STING-IRF3 responses through modulation of LATS2/VGLL3 Hippo signaling
3. 581 Ixekizumab reduces key IL-17 and IL-23 pathway genes more rapidly than guselkumab: 4-week results from IXORA-R
4. 134 Expansion of Th17 cells in CD3/CD28-activated human PBMC: Monocyte apoptosis and skin-homing T-cell bias
5. 311 Single-cell transcriptomics reveals distinct molecular programs in folliculotropic mycosis fungoides
6. 1315 Differential response of 3D African American and White Non-Hispanic skin organoids to major pro-inflammatory cytokines
7. 318 Lupus fibroblasts hyperrespond to inflammatory cytokines and upregulate pro-fibrotic collagens in patients with scarring skin lesions
8. 804 Upadacitinib normalizes the lesional and nonlesional cutaneous transcriptome in patients with moderate-to-severe atopic dermatitis
9. 818 Multi-condition TWAS for inflammatory skin disorders highlights roles of genetic signals in cytokine-stimulated keratinocytes
10. 882 Enhancer RNA (eRNA) profiling to understand transcription regulation in keratinocytes
11. 1473 Hippo pathway drives excessive fibrosis in hidradenitis suppurativa
12. 594 Hippo pathway drives excessive fibrosis in Hidradenitis Suppurativa
13. 717 TCF-4 negatively regulates IL-17C In human keratinocytes and in a mouse model of psoriasis
14. 019 Investigating OX40L and its role in mediating cutaneous and systemic autoimmune disease
15. 137 Molecular investigation of secondary syphilis in the skin characterizes the nature of the B-cell promoting inflammatory environment
16. 032 IL-36 axis is a sex-biased immune amplification circuit localized to the supraspinous epidermal compartment
17. 511 Kullback-Leibler divergence model to integrate genetic and genomic information to assess drug response for psoriatic patients
18. LB1035 Three-dimensional structural and transcriptomic analyses reveal disruption and dysfunctional repair of the dermal extracellular matrix in early striae gravidarum
19. 512 Integrative analysis using allele specific accessibility in immunocytes to unravel biological effect for complex skin-disease associated loci
20. LB967 Monogenic mutations implicate STAT1 in hidradenitis suppurativa pathogenesis
21. 482 Differences in chromatin accessibility in male vs female keratinocytes using ATAC-seq
22. 804 Fibroblast subpopulations orchestrate chronic inflammation in hidradenitis suppurativa
23. 471 Integrated psoriasis GWAS and eQTL analysis reveals risk-associated genetic control of TRAF3IP2-AS1 expression in activated CD8 T-cells
24. 505 Expanded GWAS meta-analysis offers novel insights into psoriasis biology
25. 475 High resolution chromatin loops associate with gene targets for psoriasis susceptibility regions
26. 129 Pervasive immune dysfunction characterizes photoaged skin
27. 850 Potential role of skin in SARS-CoV-2 infection
28. 142 The phenotype of dermal fibroblasts in young vs. aged human skin: Adaptation to dermal extracellular matrix deterioration and cell autonomous responses
29. 508 Skin barrier defect and inflammation in Netherton syndrome: Lessons from a comparative study of patients and mouse models
30. 447 HERC6 negatively regulates type I interferon activity in keratinocytes through modulation of STING-IRF3 signaling
31. 496 Differential chromatin accessibility and gene expression suggest Th17 polarization in activated and skin-homing T cells
32. 513 Regulatory roles of lncRNAs in psoriasis determined by single cell analysis
33. 468 Transcriptional profiling of the rare acantholytic disorders Darier disease, Hailey-Hailey disease, and Grover's disease suggests common mechanisms of pathogenesis
34. 456 Independent causal effect of psoriasis on multiple sclerosis identified by Mendelian randomization
35. 808 Lichen planus single cell and spatial profiling of cutaneous lichen planus treated with baricitinib
36. 715 Single-cell sequencing of seborrheic keratosis reveals anti-apoptotic lncRNAs MTRNR2L8 and MTRNR2L12 as potential drivers of disease
37. 528 Proteome analysis reveals activation of IL1/IRAK1/NF-κB axis in the healthy African American skin
38. 418 Hidradenitis suppurativa risk alleles identified in an ancestrally diverse HS meta-analysis of 16 cohorts
39. 410 Modeling prurigo nodularis and atopic dermatitis lesional skin identifies disease-biased regulatory mechanisms using single cell multiomic data
40. 078 Single-nuclei and spatial transcriptomics of neutrophilic dermatoses reveal a prominent interferon signature in sweet’s syndrome
41. 069 Single-cell analysis reveals distinct subpopulations of T cells and elevated IL-26 and IL-17 levels in palmoplantar pustulosis lesions
42. 016 Investigating therapeutic targeting of the female-biased factor VGLL3 in lupus
43. 026 Sex-dependent activation of keratinocytes by IL-36 cytokines
44. 019 Dynamic keratinocyte-neutrophil-fibroblast communication network characterizes inflammatory responses in generalized pustular psoriasis
45. 342 Molecular characterization of secondary syphilis through bulk, single-cell analyses and identification of the role of MYD88 in cellular responses to Treponema pallidum
46. 1096P Clinicopathologic risk factors for large cell transformation in patients with Sezary syndrome
47. 1101P Near real-time intraoperative melanoma diagnosis using deep neural networks
48. 273 Large scale functional inference for skin-expressing lncRNAs using expression and sequence information
49. 229 IRAK2 promotes abnormal epidermal differentiation during inflammatory states to facilitate and amplify immune responses in skin
50. 225 Desmoglein 1 deficiency in knockout mice impairs epidermal barrier formation and results in a psoriasis-like gene signature in E18.5 embryos
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