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1. Multiple system atrophy: Diagnostic challenges and a proposed diagnostic algorithm

Author

Nandanwar, Deepmala and Truong, Daniel D

Subjects
Veterinary Sciences, Agricultural, Veterinary and Food Sciences, Biomedical and Clinical Sciences, Biomedical Imaging, Alzheimer's Disease Related Dementias (ADRD), Acquired Cognitive Impairment, Clinical Research, Neurosciences, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Lewy Body Dementia, Parkinson's Disease, Dementia, Aging, Rare Diseases, Brain Disorders, Neurodegenerative, 4.1 Discovery and preclinical testing of markers and technologies, 4.2 Evaluation of markers and technologies, Neurological
Abstract

Multiple system atrophy (MSA) is a heterogenous condition, presenting with core clinical features of autonomic dysfunction, parkinsonism, and/or cerebellar ataxia. The presence of alpha-synuclein glial cytoplasmic inclusion is the hallmark of MSA. It shares a common pathological origin with Parkinson's disease (PD) and Lewy body dementia (DLB) and they are collectively grouped as "synucleinopathies." The pathological synuclein protein is now well- recognized in skin biopsies of these patients. Besides the pathological findings, radiological investigation is a useful diagnostic tool. Brain MRI helps rule out other etiologies, and findings like the "Hot-cross bun" sign, "putaminal atrophy," and "infratentorial findings" can assist with the diagnosis of MSA. Cardiac MIBG scan, autonomic testing, urodynamic studies can help differentiate MSA from other conditions. Although diagnostic tools are available for MSA diagnosis, clarity is needed on when to use these tests. We suggest a diagnostic algorithm to navigate the use of these tests. However, this algorithm is not intended to replace the use of current MDS diagnostic criteria of MSA.

Published
2024

4. Guidelines for the Use of Parkinsonian Drugs (in USA)

Author

Vo, Trang N. N., Frei, Karen, Truong, Daniel D., Nagatsu, Toshiharu, Section editor, Nakashima, Akira, Section editor, Riederer, Peter, editor, Laux, Gerd, editor, Nagatsu, Toshiharu, editor, Le, Weidong, editor, and Riederer, Christian, editor

Published
2022
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6. Immediate-release/extended-release amantadine (OS320) to treat Parkinson's disease with levodopa-induced dyskinesia: Analysis of the randomized, controlled ALLAY-LID studies

Author

Azulay, Jean-Philippe, Balaguer, Ernest, Bhatia, Perminder, Bodis-Wollner, Ivan, Brownstone, Paul, Boulloche, Nicolas, Calegan, Gerald J., II, Castelnovo, Giovanni, Chou, Kelvin L., Corvol, Jean-Christophe, Danisi, Fabio, Defebvre, Luc, Desojo, Lydia Vela, Durif, Franck, Ehret, Reinhard, Evans, Bradley K., Forchetti, Concetta, Friedman, Joseph H., Fogel, Wolfgang, Garniga, Matilde Calopa, Gil, Ramon A., Ginsberg, Paul L., Glasberg, Mark R., Griffith, Alida, Groves, Jeffrey W., Gudesblatt, Mark, Hermanowicz, Neal, Herrera, Maria A., Houeto, Jean-Luc, Hutchman, Robert M., Isaacson, Stuart H., Jagadeesan, Singar, Jog, Mandar, Keegan, Andrew, Klostermann, Fabian, Krystkowiak, Pierre, Kulisevsky Bojarsky, Jaime, Kumar, Rajeev, Lacey, Dennis, Lasker, Bruce, LaVaccare, John, Lavallee, Michelle M., Piudo, Maria Rosario Luquin, Mahler, Andreas, Domenech, Maria José Martí, Martinez Castrillo, Juan Carlos, Mate, Laszlo J., Mendis, Tilak, Metman, Leonard Verhagen, Muhlack, Siegfried Martin, Müller, Thomas, Park, Ariane, Patton, James, Peckham, Elizabeth, Grandas Pérez, Francisco, Rabin, Marcie, Rascol, Olivier, Reifschneider, Gerd, Remy, Philippe, Rivera, Pablo Mir, Schwarz, Johannes, Roullet-Solignac, Isabelle, Salazar, Gabriel, Sergay, Stephen M., Sherman, Scott, Shubin, Richard, Spikol, Lorraine, Steigerwald, Frank, Tönges, Lars, Truong, Daniel D., Ugarte, Antonio, Vivancos Matellano, Francisco, Witte, Arnold, Zesiewicz, Theresa, Zauber, Sarah Elizabeth, deVries, Tina, Jaros, Mark, Quartel, Adrian, and Jacobs, David

Published
2022
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18. Immediate-release/extended-release amantadine (OS320) to treat Parkinson's disease with levodopa-induced dyskinesia: Analysis of the randomized, controlled ALLAY-LID studies

Author

Rascol, Olivier, primary, Tönges, Lars, additional, deVries, Tina, additional, Jaros, Mark, additional, Quartel, Adrian, additional, Jacobs, David, additional, Azulay, Jean-Philippe, additional, Balaguer, Ernest, additional, Bhatia, Perminder, additional, Bodis-Wollner, Ivan, additional, Brownstone, Paul, additional, Boulloche, Nicolas, additional, Calegan, Gerald J., additional, Castelnovo, Giovanni, additional, Chou, Kelvin L., additional, Corvol, Jean-Christophe, additional, Danisi, Fabio, additional, Defebvre, Luc, additional, Desojo, Lydia Vela, additional, Durif, Franck, additional, Ehret, Reinhard, additional, Evans, Bradley K., additional, Forchetti, Concetta, additional, Friedman, Joseph H., additional, Fogel, Wolfgang, additional, Garniga, Matilde Calopa, additional, Gil, Ramon A., additional, Ginsberg, Paul L., additional, Glasberg, Mark R., additional, Griffith, Alida, additional, Groves, Jeffrey W., additional, Gudesblatt, Mark, additional, Hermanowicz, Neal, additional, Herrera, Maria A., additional, Houeto, Jean-Luc, additional, Hutchman, Robert M., additional, Isaacson, Stuart H., additional, Jagadeesan, Singar, additional, Jog, Mandar, additional, Keegan, Andrew, additional, Klostermann, Fabian, additional, Krystkowiak, Pierre, additional, Kulisevsky Bojarsky, Jaime, additional, Kumar, Rajeev, additional, Lacey, Dennis, additional, Lasker, Bruce, additional, LaVaccare, John, additional, Lavallee, Michelle M., additional, Piudo, Maria Rosario Luquin, additional, Mahler, Andreas, additional, Domenech, Maria José Martí, additional, Martinez Castrillo, Juan Carlos, additional, Mate, Laszlo J., additional, Mendis, Tilak, additional, Metman, Leonard Verhagen, additional, Muhlack, Siegfried Martin, additional, Müller, Thomas, additional, Park, Ariane, additional, Patton, James, additional, Peckham, Elizabeth, additional, Grandas Pérez, Francisco, additional, Rabin, Marcie, additional, Rascol, Olivier, additional, Reifschneider, Gerd, additional, Remy, Philippe, additional, Rivera, Pablo Mir, additional, Schwarz, Johannes, additional, Roullet-Solignac, Isabelle, additional, Salazar, Gabriel, additional, Sergay, Stephen M., additional, Sherman, Scott, additional, Shubin, Richard, additional, Spikol, Lorraine, additional, Steigerwald, Frank, additional, Truong, Daniel D., additional, Ugarte, Antonio, additional, Vivancos Matellano, Francisco, additional, Witte, Arnold, additional, Zesiewicz, Theresa, additional, and Zauber, Sarah Elizabeth, additional

Published
2022
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25. Contributors

Author

Ajjuri, Rami R., primary, Ali, Yousuf, additional, Arena, Giuseppe, additional, Ashizawa, Tetsuo, additional, Auburger, Georg, additional, Bagchi, Devika P., additional, Baldo, Barbara, additional, Baxter, Sally L., additional, Berman, Robert F., additional, Binder, Lester I., additional, Blackstone, Craig, additional, Breda, Carlo, additional, Brotchie, Jonathan M., additional, Burton, Edward A., additional, Calderon, Diany Paola, additional, Caldwell, Guy A., additional, Caldwell, Kim A., additional, Cenci, M. Angela, additional, Chen, Jianmin, additional, Chesselet, Marie-Francoise, additional, Collins-Praino, Lyndsey E., additional, Colosimo, Carlo, additional, Combs, Benjamin, additional, Correa, Mercè, additional, D’Adamo, Maria Cristina, additional, Dai, Helena, additional, Datta, Debkanya, additional, DeAndrade, Mark P., additional, Dietrich, Paula, additional, Dragatsis, Ioannis, additional, Eidelberg, David, additional, El-Khamisy, Sherif F., additional, Evinger, Craig L., additional, Fassier, Coralie, additional, Figiel, Maciej, additional, Fox, Susan H., additional, Francardo, Veronica, additional, Freeman, Amanda A.H., additional, Frucht, Steven, additional, Gardiner, John, additional, Giasson, Benoit, additional, Giorgini, Flaviano, additional, Gispert, Suzana, additional, González-Cabo, Pilar, additional, Gradinaru, Viviana, additional, Hall, Marleshia, additional, Hama, Hiroko, additional, Handforth, Adrian, additional, Hayflick, Susan, additional, Hazan, Jamilé, additional, Hedera, Peter, additional, Heiman, Gary A., additional, Herrup, Karl, additional, Hess, Ellen J., additional, Hickey, Patrick, additional, Himmelstein, Diana S., additional, Hoekstra, Pieter J., additional, Houart, Corinne, additional, Hunsaker, Michael Ryan, additional, Iderberg, Hanna, additional, Jackson-Lewis, Vernic, additional, Jankovic, Joseph, additional, Jinnah, H.A., additional, Joensuu, Tarja, additional, Johnston, Tom M., additional, Josephs, Keith A., additional, Kanaan, Nicholas M., additional, Khodakhah, Kamran, additional, Kim, Kwang-Soo, additional, Klinker, F., additional, Kooner, Gurdeep S., additional, Kopra, Outi, additional, Kotzbauer, Paul T., additional, Kozina, Elena, additional, Krismer, Florian, additional, Krzyzosiak, Wlodzimierz J., additional, Kuruvilla, Korah P., additional, Kuzdas, Daniela, additional, Kyriacou, Charalambos P., additional, Leavitt, Blair R., additional, LeDoux, Mark S., additional, Lehesjoki, Anna-Elina, additional, Lester, Deranda, additional, Lewis, Jada, additional, Li, Jiali, additional, Liebetanz, D., additional, Lindgren, Hanna, additional, Mallucci, Giovanna R., additional, Mann, Amandeep, additional, Margolis, Russell L., additional, Mason, Robert P., additional, Mazarei, Gelareh, additional, McDonald, Michael P., additional, Melki, Judith, additional, Méneret, Aurélie, additional, Moscovich, Mariana, additional, Neuner, Irene, additional, O’Donnell, Janis M., additional, Oleas, Janneth, additional, Ondo, William G., additional, Opal, Puneet, additional, Orr, Harry T., additional, Ozdowski, Emily F., additional, Pandolfo, Massimo, additional, Paschou, Peristera, additional, Pascual, Juan M., additional, Patel, Amar, additional, Patel, Neepa, additional, Peres, João N., additional, Pessia, Mauro, additional, Petersén, Åsa, additional, Petrucci, Simona, additional, Pfeiffer, Ronald F., additional, Phielipp, Nicolás M., additional, Pienaar, Ilse Sanet, additional, Pittenger, Christopher, additional, Plummer, Mark R., additional, Podurgiel, Samantha, additional, Przedborski, Serge, additional, Puschmann, Andreas, additional, Reiter, Lawrence T., additional, Ren, Yan, additional, Renvoisé, Benoît, additional, Rose, Samuel J., additional, Ross, Owen A., additional, Roze, Emmanuel, additional, Ruan, Kai, additional, Rudnicki, Dobrila D., additional, Sahara, Naruhiko, additional, Sako, Wataru, additional, Salamone, John D., additional, Sanyal, Subhabrata, additional, Saunders, Thomas L., additional, Schneider, Susanne A., additional, Schulte, Eva C., additional, Schwartzer, Jared J., additional, Sherwood, Nina T., additional, Sibon, Ody, additional, Smeyne, Richard J., additional, Stacy, Mark, additional, Starr, Philip, additional, Staveley, Brian E., additional, Stefanova, Nadia, additional, Subramony, S.H., additional, Swann, Nicole, additional, Switonski, Pawel M., additional, Szlachcic, Wojciech J., additional, Tai, Kwok-Keung, additional, Tiranti, Valeria, additional, Truong, Daniel D., additional, Tyynismaa, Henna, additional, Uluğ, Aziz M., additional, Valente, Enza M., additional, Van Gerpen, Jay A., additional, Vázquez-Manrique, Rafael P., additional, Vemula, Satya, additional, Vidailhet, Marie, additional, Walker, Ruth H., additional, Ward, Sarah M., additional, Wells, Owen S., additional, Wenning, Gregor K., additional, Willet, Kathleen A., additional, Winkelmann, Juliane, additional, Wszolek, Zbigniew K., additional, Xiao, Jianfeng, additional, Yang, X. William, additional, Ylikallio, Emil, additional, Yokoi, Fumiaki, additional, Yue, Zhenyu, additional, and Zhai, R. Grace, additional

Published
2015
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39. The C.-237_236GA>TT THAP1 Sequence Variant Does Not Increase Risk for Primary Dystonia

Author

Xiao, Jianfeng, Zhao, Yu, Bastian, Robert W., Perlmutter, Joel S., Racette, Brad A., Tabbal, Samer D., Karimi, Morvarid, Paniello, Randal C., Wszolek, Zbigniew K., Uitti, Ryan J., Van Gerpen, Jay A., Simon, David K., Tarsy, Daniel, Hedera, Peter, Truong, Daniel D., Frei, Karen P., Blitzer, Andrew, Rudzińska, Monika, Pfeiffer, Ronald F., Le, Carrie, and LeDoux, Mark S.

Published
2011
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42. List of Contributors

Author

Ashizawa, Tetsuo, primary, Baier, P.C., additional, Becker, Lore, additional, Bennett, David J., additional, Berke, Brett, additional, Betarbet, Ranjita, additional, Bhatia, Kailash P., additional, Bibbiani, Francesco, additional, Blake, David T., additional, Borchelt, David R., additional, Bose, Prodip, additional, Bragg, D. Cristopher, additional, Brashear, Allison, additional, Breakefield, Xandra O., additional, Bressman, Susan, additional, Burke, Kathleen, additional, Byl, Nancy N., additional, Caldwell, Guy A., additional, Caldwell, Kim A., additional, Cao, Songsong, additional, Cenci, M. Angela, additional, Chesselet, Marie-Françoise, additional, Colosimo, Carlo, additional, Dang, Mai, additional, Dennis, Julie A., additional, Devys, Didier, additional, Dietrich, Paula, additional, Dragatsis, Ioannis, additional, D'Souza, Ian, additional, Elble, Rodger J., additional, Evinger, Craig, additional, Fernagut, Pierre-Olivier, additional, Fernandez, Hubert H., additional, Fink, John K., additional, Fleming, Sheila M., additional, Fletcher, Colin F., additional, Fox, Lyle, additional, Fowler, Stephen C., additional, Friedman, Joseph H., additional, Geser, Felix, additional, Ghorayeb, Imad, additional, Gorassini, Monica, additional, Greenamyre, J. Timothy, additional, Harvey, Philip J., additional, Heales, Simon J.R., additional, Healy, Peter J., additional, Helmlinger, Dominique, additional, Hess, Ellen J., additional, Hillman, Ralph, additional, Homanics, Gregg E., additional, Hyland, Keith, additional, Izevbaye, Iyare, additional, Jackson-Lewis, Vernice, additional, Jinnah, H.A., additional, Jurkowski, Anita J., additional, Kassem, Iris S., additional, Kaytor, Michael D., additional, Kralic, Jason E., additional, LeDoux, Mark, additional, Lewis, Jada, additional, Li, Yuqing, additional, Lieberman, David, additional, Linn, Gary S., additional, Litvan, Irene, additional, Lombroso, Paul J., additional, Louis, Elan D., additional, Lundblad, Martin, additional, Marsh, J. Lawrence, additional, McGowan, Eileen, additional, McKerchar, T.L., additional, Merzenich, Michael, additional, Morrow, A. Leslie, additional, Naquet, Robert, additional, Nass, Richard, additional, Navas, Parvoneh Poorkaj, additional, O'Buckley, Todd K., additional, Oh, Justin D., additional, Ohye, Chihiro, additional, Orr, Harry T., additional, Osterman, Jessica L., additional, Pallanck, Leo J., additional, Pandolfo, Massimo, additional, Pendleton, Robert G., additional, Peng, Haixiang, additional, Peng, I-Feng, additional, Perez, Dianne M., additional, Perlman, Susan L., additional, Perlmutter, Joel S., additional, Petravicz, Jeremy, additional, Pfeiffer, Ronald F., additional, Phillips, James O., additional, Pranzatelli, Michael R., additional, Pulst, Stefan-M., additional, Rainier, Shirley, additional, Rao, Jayaraman, additional, Richter, Angelika, additional, Robinson, Farrel R., additional, Ross, Christopher A., additional, Sachdev, Perminder S., additional, Saunders-Pullman, Rachel, additional, Schellenberg, Gerard D., additional, Schilling, Gabriele, additional, Schofield, Peter R., additional, Sharma, Nutan, additional, Sherer, Todd B., additional, Silva-Barrat, Carmen, additional, Singer, Harvey S., additional, Smeyne, Richard Jay, additional, Smith-Hicks, Constance, additional, Stacy, Mark, additional, Stafanova, Nadia, additional, Standaert, David G., additional, Subramony, S.H., additional, Tabbal, Samer D., additional, Tai, Kwok-Keung, additional, Thompson, Floyd J., additional, Thompson, Leslie M., additional, Tison, François, additional, Trenkwalder, Claudia, additional, Truong, Daniel D., additional, Ueda, Atsushi, additional, Vartiainen, Suvi, additional, Weiher, Hans, additional, Weiss, Avery H., additional, Wenning, Gregor Karl, additional, Whitworth, Alexander J., additional, Windsor, Peter A., additional, Wong, Garry, additional, Wu, Chun-Fang, additional, and Zarcone, T.J., additional

Published
2005
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46. Foreward

Author

Truong, Daniel D., Dressler, Dirk, and Hallett, Mark

Published
2006

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