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Your search keyword '"Trueba, Elvira"' showing total 7 results
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7 results on '"Trueba, Elvira"'

1. Clinical Results of a −80°C Simplified Cryo-Preservation Method.

Author

Escoboza, Jose R. Borbolla, primary, Lopez-Hernandez, Manuel A., primary, Garza, Marcos E., primary, Baez, Enrique, primary, Trueba, Elvira, primary, Hernandez, Roberto, primary, DeDiego-FloresChapa, Jose E., primary, Baltazar, Severiano, primary, Alvarado, Martha, primary, Villareal, Gerardo, primary, Gonzalez-Avante, Mauricio C., primary, De Leon, Rosa E., primary, Cedillo, Jose L., primary, Penniecook, Jason A., primary, Tovar, Yara E., primary, Leon, Maria I., primary, and Ramirez-Assad, Cecilia, primary

Published
2004
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2. Frequency of Genetic Deletions of the Glutathione-S Transferase (Gst) Gene in Mexican Patients with De Novo Acute Leukemia: A Preliminary Report from the “Instituto Tecnologico De Monterrey-Hematology Research Group”.

Author

Escoboza, Jose R. Borbolla, primary, Garza-Madrid, Marcos E., primary, Alvarado, Martha, primary, Baez, Enrique, primary, Lopez-Hernández, Manuel A., primary, DeDiego, Jose E., primary, Baltazar, Severiano, primary, Leon-Castanon, Maria I., primary, Rojas-Martinez, Julio C., primary, Ramirez-Assad, Cecilia, primary, Trueba, Elvira, primary, Villarreal, Gerardo, primary, Villela, Luis M., primary, Cruz-Rico, Jorge, primary, Tejeda, Monica, primary, Duque, Jorge, primary, Gonzalez-Avante, Mauricio C., primary, Pompa, Teresa, primary, Anaya, Irene, primary, Ochoa, Leonel, primary, Gonzalez, Guadalupe, primary, de la Luz Mendizabal, Maria, primary, Jimenez, Rosa M., primary, Hernandez, Roberto, primary, Mejia, Dolores, primary, Romero, Eduardo, primary, Gil-Rondero, Carlos, primary, Juarez, Jorge L., primary, De Leon, Rosa E., primary, Tovar, Yara E., primary, and Penniecook, Jason A., primary

Published
2004
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6. Frequency of Genetic Deletions of the Glutathione-S Transferase (Gst) Gene in Mexican Patients with De NovoAcute Leukemia: A Preliminary Report from the “Instituto Tecnologico De Monterrey-Hematology Research Group”.

Author

Escoboza, Jose R. Borbolla, Garza-Madrid, Marcos E., Alvarado, Martha, Baez, Enrique, Lopez-Hernández, Manuel A., DeDiego, Jose E., Baltazar, Severiano, Leon-Castanon, Maria I., Rojas-Martinez, Julio C., Ramirez-Assad, Cecilia, Trueba, Elvira, Villarreal, Gerardo, Villela, Luis M., Cruz-Rico, Jorge, Tejeda, Monica, Duque, Jorge, Gonzalez-Avante, Mauricio C., Pompa, Teresa, Anaya, Irene, Ochoa, Leonel, Gonzalez, Guadalupe, de la Luz Mendizabal, Maria, Jimenez, Rosa M., Hernandez, Roberto, Mejia, Dolores, Romero, Eduardo, Gil-Rondero, Carlos, Juarez, Jorge L., De Leon, Rosa E., Tovar, Yara E., and Penniecook, Jason A.

Abstract

Although there have been extraordinary advances in leukemia therapy, there is still a large subset of cases in which complete remission or prolonged leukemia-free survival cannot be achieved. Some of this variability in results is thought to be related to the differences in the effect of chemotherapy drugs on different patients. In many cases, these differences may be associated with the presence of genetic alterations that produce defective drug-metabolizing enzymes, drug transporters or drug targets. One of these is the glutathione-S transferase (GST) gene, which is known to catalyze the conjugation of toxic compounds, such as aliphatic aromatic heterocyclic radicals and epoxides, among others, to glutathione. The enzymes encoded by this gene detoxify polycyclic aromatic hydrocarbons and conjugated isothiocyanates.

Published
2004
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7. A randomized trial of dexamethasone before remission induction, in de novo childhood acute lymphoblastic leukemia.

Author

López-Hernández MA, Alvarado M, De Diego J, Borbolla-Escoboza JR, Jiménez RM, and Trueba E

Subjects
Child, Drug Administration Schedule, Female, Humans, Male, Remission Induction, Antineoplastic Combined Chemotherapy Protocols administration & dosage, Dexamethasone administration & dosage, Precursor Cell Lymphoblastic Leukemia-Lymphoma drug therapy
Abstract

We evaluated the impact of adding dexamethasone before chemotherapy in 95 children with de novo standard-risk acute lymphoblastic leukemia (ALL). The children were randomly divided into 2 groups: one group was given dexamethasone, the other was not. The initial characteristics and mean follow-up of both groups were similar. Day +14 blast percentage was significantly lower in the dexamethasone group. Disease-free survival at 40-months follow-up was better (almost significantly so) in the dexamethasone group.

Published
2004

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