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161 results on '"Trudzinski, F"'

1. Statins did not reduce the frequency of exacerbations in individuals with COPD and cardiovascular comorbidities in the COSYCONET cohort

Author

Frantzi, N., Nguyen, X. P., Herr, C., Alter, P., Söhler, S., Soriano, D., Watz, H., Waschki, B., Trinkmann, F., Eichenlaub, M., Trudzinski, F. C., Michels-Zetsche, J. D., Omlor, A., Seiler, F., Moneke, I., Biertz, F., Rohde, G., Stolz, D., Welte, T., Kauczor, H. U., Kahnert, K., Jörres, R. A., Vogelmeier, C. F., Bals, R., and Fähndrich, S.

Published
2024
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2. Midregional proatrial naturetic peptide (MRproANP) and copeptin (COPAVP) as predictors of all-cause mortality in recently diagnosed mild to moderate COPD—results from COSYCONET

Author

Fähndrich, S., Herr, C., Teuteberg, S., Alter, P., Söhler, S., Soriano, D., Classen, J., Adams, J., Weinhold, V., Watz, H., Waschki, B., Zeller, T., Eichenlaub, M., Trudzinski, F. C., Michels, J. D., Omlor, A., Seiler, F., Moneke, I., Biertz, F., Stolz, D., Welte, T., Kauczor, H. U., Kahnert, K., Jörres, R. A., Vogelmeier, C. F., and Bals, R.

Published
2024
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3. Endobronchial Valve Replacements in Patients with Advanced Emphysema After Endoscopic Lung Volume Reduction

Author

Brock JM, Schuster PU, Böhmker F, Eberhardt R, Gompelmann D, Kontogianni K, Trudzinski F, Benjamin N, and Herth F

Subjects
endobronchial lung volume reduction, endobronchial valves, valve replacement, revision bronchoscopy, copd, Diseases of the respiratory system, RC705-779
Abstract

Judith Maria Brock,1,2 Paul Ulrich Schuster,3 Felix Böhmker,3 Ralf Eberhardt,4 Daniela Gompelmann,5 Konstantina Kontogianni,1,2 Franziska Trudzinski,1,2 Nicola Benjamin,1 Felix Herth1,2 1Department of Pneumology and Critical Care Medicine, Thoraxklinik at University of Heidelberg, Heidelberg, Germany; 2Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany; 3Medical Faculty, University of Heidelberg, Heidelberg, Germany; 4Department of Pneumology and Intensive Care Medicine, Asklepios Klinik Barmbek, Hamburg, Germany; 5Department of Internal Medicine II, Division of Pulmonology, Medical University of Vienna, Vienna, AustriaCorrespondence: Judith Maria Brock, Department of Pneumology and Critical Care Medicine, Thoraxklinik Heidelberg, University Hospital of Heidelberg, Röntgenstraße 1, Heidelberg, 69126, Germany, Tel +49 6221-3968256, Email Judith.Brock@med.uni-heidelberg.dePurpose: Up to 41% of patients with endobronchial valve implantation need revision bronchoscopies and valve replacements most likely due to valve dysfunction or lack of benefit. So far, no data is available whether valve replacements lead to the desired lobar volume reduction and therapy benefit.Patients and Methods: We conducted a single-center retrospective analysis of patients with endobronchial valve implantation and at least one valve replacement. Indications and number of revision bronchoscopies and valve replacements were evaluated. Therapy benefit regarding lung function and exercise capacity as well as development of complete lobar atelectasis was investigated and possible predictors identified.Results: We identified 73 patients with 1– 12 revision bronchoscopies and 1– 5 valve replacements. The main indication for revision bronchoscopy in this group was lack of therapy benefit (44.2%). Lung function and exercise capacity showed improvements in about one-third of patients even years after the initial implantation. A total of 26% of all patients showed a complete lobar atelectasis at the end of the observation period, 56.2% had developed lung volume reduction. The logistic regression revealed the development of a previous complete lobar atelectasis as predictor for a complete lobar atelectasis at final follow-up. Oral cortisone long-term therapy was also shown as predictive factor. The probability for a final complete lobar atelectasis was 69.2% if a lobar atelectasis had developed before.Conclusion: Valve replacements are more likely to be beneficial in patients who develop a re-aeration of a previous lobar atelectasis following valve implantation. Every decision for revision bronchoscopy must be taken carefully.Keywords: endobronchial lung volume reduction, endobronchial valves, valve replacement, revision bronchoscopy, COPD

Published
2023

8. Effects of triple therapy in patients of GOLD group C and D: Results from the observational COPD cohort COSYCONET

Author

Zader, J, additional, Jörres, R, additional, Mayer, I, additional, Alter, P, additional, Bals, R, additional, Watz, H, additional, Mertsch, P, additional, Rabe, K, additional, Herth, F, additional, Trudzinski, F, additional, Welte, T, additional, Kauczor, H, additional, Behr, J, additional, Walter, J, additional, Vogelmeier, C, additional, and Kahnert, K, additional

Published
2023
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9. Erste Erfahrungen zum Einsatz eines E-learning Angebotes zur Verbesserung der Weaning-Kompetenz im Rahmen der PRiVENT-Intervention

Author

Trudzinski, F, additional, Schubert-Haack, J, additional, Neetz, B, additional, Tanck, K, additional, Iberl, G, additional, Müeller, M, additional, Kempa, A, additional, Neurohr, C, additional, Forstner, J, additional, Ghiani, A, additional, Andritschky, C, additional, Schneider, A, additional, Rheinhold, A, additional, Gehrig, P, additional, Szecsenyi, J, additional, and Herth, F, additional

Published
2023
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17. COVID-19-disease prevalence and its characteristics among health care workers of specialized respiratory clinics in Germany one year after the start of vaccination campaign

Author

Presotto, M A, primary, Piel, S, additional, Jörres, R A, additional, Karrasch, S, additional, Gesierich, W, additional, Bullwinkel, J, additional, Rabe, K F, additional, Hayden, M, additional, Kaestner, F, additional, Harzheim, D, additional, Joves, B, additional, Kempa, A T, additional, Ghiani, A, additional, Neurohr, C, additional, Kreuter, M, additional, Herth, F J F, additional, and Trudzinski, F C, additional

Published
2022
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18. Risk factors for pandemic-related workplace absenteeism among health care workers and the impact of vaccination

Author

Piel, S, primary, Presotto, M A, additional, Jörres, R A, additional, Karrasch, S, additional, Gesierich, W, additional, Bullwinkel, J, additional, Rabe, K F, additional, Hayden, M, additional, Kaestner, F, additional, Harzheim, D, additional, Joves, B, additional, Kempa, A T, additional, Ghiani, A, additional, Neurohr, C, additional, Kreuter, M, additional, Herth, F J, additional, and Trudzinski, F C, additional

Published
2022
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20. Proadrenomedullin and copeptin are more sensitive and specific biomarkers for the prediction of mortality in stable COPD than fibrinogen: An analysis of the COSYCONET study

Author

Fähndrich, S, primary, Teuteberg, S, additional, Herr, C, additional, Watz, H, additional, Waschki, B, additional, Trudzinski, F C, additional, Omlor, A, additional, Alter, P, additional, Seiler, F, additional, Biertz, F, additional, Welte, T, additional, Kauczor, H, additional, Jörres, R A, additional, Vogelmeier, C F, additional, Bals, R, additional, and Stolz, D, additional

Published
2022
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22. Factors underlying the increasing prevalence of comorbidities over time and their mutual relationship in COPD: Results from COSYCONET

Author

Alter, P, primary, Kahnert, K, additional, Trudzinski, F C, additional, Bals, R, additional, Watz, H, additional, Speicher, T, additional, Söhler, S, additional, Andreas, S, additional, Welte, T, additional, Rabe, K F, additional, Wouters, E F, additional, Lange, C, additional, Wirtz, H, additional, Ficker, J H, additional, Vogelmeier, C F, additional, and Jörres, R A, additional

Published
2022
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24. EP08.01-031 Blood Gene Expression Changes in Metastatic Lung Cancer under second-line Immunotherapy according to Clinical Response

Author

Lusky, F., primary, Schindler, H., additional, Elshiaty, M., additional, Gaissmaier, L., additional, Daniello, L., additional, Bozorgmehr, F., additional, Kuon, J., additional, Shah, R., additional, Schneider, M.A., additional, Eichhorn, F., additional, Trudzinski, F., additional, Angeles, A., additional, Janke, F., additional, Kirchner, M., additional, Kazdal, D., additional, Stenzinger, A., additional, Sültmann, H., additional, Thomas, M., additional, and Christopoulos, P., additional

Published
2022
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27. AB0685 Oxygenated hemoglobin as prognostic marker among patients with systemic sclerosis screened for pulmonary hypertension

Author

Xanthouli, P., primary, Gordjani, O., additional, Eichstaedt, C., additional, Benjamin, N., additional, Trudzinski, F., additional, Egenlauf, B., additional, Harutyunova, S., additional, Marra, A., additional, Milde, N., additional, Nagel, C., additional, Blank, N., additional, Lorenz, H. M., additional, and Grünig, E., additional

Published
2022
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31. Prädiktoren von Mortalität und Exazerbationen bei Patienten mit stabiler COPD: Ergebnisse von COSYCONET

Author

Alter, P, additional, Lucke, T, additional, Watz, H, additional, Andreas, S, additional, Kahnert, K, additional, Trudzinski, F C, additional, Speicher, T, additional, Söhler, S, additional, Bals, R, additional, Waschki, B, additional, Welte, T, additional, Rabe, K F, additional, Vestbo, J, additional, EFM, Wouters, additional, Vogelmeier, C F, additional, and Jörres, R A, additional

Published
2022
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34. Risikofaktoren für eine invasive Langzeitbeatmung – ein Systematic Literature Review

Author

Trudzinski, F C, additional, Bornitz, F, additional, Müller, M M, additional, Weis, A, additional, Neetz, B, additional, Kronsteiner, D, additional, FJF, Herth, additional, Sturm, N, additional, Gassmann, V, additional, Joveš, B, additional, Neurohr, C, additional, Ghiani, A, additional, Schneider, A, additional, Szecsenyi, J, additional, von Schumann, S, additional, and Meis, J, additional

Published
2022
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36. Geschlechtsspezifische Unterschiede des Komorbidoms und des Pulmorbidoms im Hinnblick auf die Prognose der COPD: Ergebnisse von COSYCONET

Author

Trudzinski, F C, additional, Jörres, R A, additional, Alter, P, additional, Walter, J, additional, Watz, H, additional, Koch, A, additional, John, M, additional, Lommatzsch, M, additional, Vogelmeier, C F, additional, Kauczor, H U, additional, Welte, T, additional, Behr, J, additional, Tufman, A, additional, Bals, R, additional, Herth, FJ F, additional, and Kahnert, K, additional

Published
2022
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37. Quality of life 3 and 12 months following acute pulmonary embolism analysis from a prospective multicenter cohort study

Author

Valerio, L., Barco, S., Jankowski, M., Rosenkranz, S., Lankeit, M., Held, M., Gerhardt, F., Bruch, L., Ewert, R., Faehling, M., Freise, J., Ghofrani, H.A., Grunig, E., Halank, M., Hoeper, M.M., Klok, F.A., Leuchte, H.H., Mayer, E., Meyer, F.J., Neurohr, C., Opitz, C., Schmidt, K.H., Seyfarth, H.J., Trudzinski, F., Wachter, R., Wilkens, H., Wild, P.S., and Konstantinides, S.V.

Subjects
Male, Time Factors, pulmonary embolism, Middle Aged, Prognosis, humanities, Survival Rate, quality of life, 5D-5L, patient-reported outcomes, Germany, Surveys and Questionnaires, patient-centered outcomes, PeMB-QoL, Acute Disease, Humans, Female, Prospective Studies, VTE, Aged, Follow-Up Studies
Abstract

Few data are available on the long-term course and predictors of quality of life (QoL) following acute pulmonary embolism (PE).What are the kinetics and determinants of disease-specific and generic health-related QoL 3 and 12 months following an acute PE?The Follow-up after Acute Pulmonary Embolism (FOCUS) study prospectively followed up consecutive adult patients with objectively diagnosed PE. Patients were considered for study who completed the Pulmonary Embolism Quality of Life (PEmb-QoL) questionnaire at predefined visits 3 and 12 months following PE. The course of disease-specific QoL as assessed using the PEmb-QoL and the impact of baseline characteristics using multivariable mixed effects linear regression were studied; also assessed was the course of generic QoL as evaluated by using the EuroQoL Group 5-Dimension 5-Level utility index and the EuroQoL Visual Analog Scale.In 620 patients (44% women; median age, 62 years), overall disease-specific QoL improved from 3 to 12 months, with a decrease in the median PEmb-QoL score from 19.4% to 13.0% and a mean individual change of -4.3% (95% CI, -3.2 to -5.5). Female sex, cardiopulmonary disease, and higher BMI were associated with worse QoL at both 3 and 12 months. Over time, the association with BMI became weaker, whereas older age and previous VTE were associated with worsening QoL. Generic QoL also improved: the mean ± SD EuroQoL Group 5-Dimension 5-Level utility index increased from 0.85 ± 0.22 to 0.87 ± 0.20 and the visual analog scale from 72.9 ± 18.8 to 74.4 ± 19.1.In a large cohort of survivors of acute PE, the change of QoL was quantified between months 3 and 12 following diagnosis, and factors independently associated with lower QoL and slower recovery of QoL were identified. This information may facilitate the planning and interpretation of clinical trials assessing QoL and help guide patient management.German Clinical Trials Registry (Deutsches Register Klinischer Studien: www.drks.de); No.: DRKS00005939.

Published
2021

49. Geschlechtsspezifische Unterschiede in der Symptomatik der COPD und deren Einfluss auf die Diagnostik kardialer Komorbiditäten

Author

Trudzinski, F C, additional, Kellerer, C, additional, Jörres, R, additional, Alter, P, additional, Lutter, J, additional, Trinkmann, F, additional, Herth, F JF, additional, Frankenberger, M, additional, Watz, H, additional, Vogelmeier, C F, additional, Kauczor, H U, additional, Welte, T, additional, Behr, J, additional, Bals, R, additional, and Kahnert, K, additional

Published
2021
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50. The effects of a short-term physician training on smoking cessation in a university pulmonary department

Author

Bauer, A, Brenner, L, Moser, J, Trudzinski, F, Köllner, V, Bals, R, Bauer, A, Brenner, L, Moser, J, Trudzinski, F, Köllner, V, and Bals, R

Abstract

Objective: The objective was to evaluate the effect of a short physician training in smoking cessation on the physicians' performance of smoking cessation interventions. The effects on patients' cessation rates were analyzed as well. A further aim was to identify barriers for providing cessation interventions. The study was conducted in an acute care pulmonology department of a German university hospital.Methods: 24 physicians of the pulmonology department of a German university hospital received a two-hour training in smoking cessation. 109 pre- and 89 post-training group patients were compared with regard to the frequencies of received smoking cessation interventions (Ask, Advise, Assist) and three- and six-month abstinence rates. Physicians estimated their intervention frequencies and gave reasons for not providing cessation interventions.Results: In a multivariable analysis (p<0.05), the physicians' application of "Ask" (OR 3.28, 95% CI 1.13-9.53) and the six-month abstinence rates (OR 2.70, 95% CI 1.24-5.84) were significantly higher in the post-training group. The univariate analysis also showed a significant effect on "Assist" (OR 2.05, 95% CI 1.09-3.87). No significant effect was seen on "Advise to quit". Physicians overestimated their intervention frequencies and reported the patients' low motivation to stop, an oncological disease and palliative care situation as barriers to performing smoking cessation.Conclusion: A short physician training in a hospital department of pulmonology increases the use of guideline-based cessation strategies and may improve cessation rates. The findings show that hospital-based strategies such as physician trainings could be useful in the improvement of smoking cessation. Strategies for overcoming barriers for providing smoking cessation interventions are needed., Ziel: Das Ziel war die Evaluation der Effekte einer Ärzte-Kurzschulung zur Raucherentwöhnung auf die Anwendungshäufigkeit der Entwöhnungsstrategien durch die Ärzte. Ebenso wurden die Effekte auf die Abstinenzraten der Patienten untersucht. Außerdem sollten die Barrieren für die Durchführung von Raucherentwöhnungsmaßnahmen ermittelt werden. Die Studie wurde in einer pneumologischen Akutklinik eines deutschen Universitätsklinikums durchgeführt.Methoden: 24 Ärzte erhielten eine zweistündige Schulung zur Raucherentwöhnung. 109 Kontrollgruppenpatienten, die vor der Schulung in der Klinik behandelt wurden, wurden mit 89 nach der Schulung behandelten Studiengruppenpatienten hinsichtlich der Häufigkeit der ärztlichen Raucherentwöhnungsinterventionen (Ask, Advise, Assist) und ihrer Abstinenzraten drei und sechs Monate nach Klinikaufenthalt verglichen. Die Ärzte schätzten ihre Interventionshäufigkeiten und gaben Gründe an, warum sie in manchen Fällen keine Entwöhnungsinterventionen durchführten.Ergebnisse: Die Anwendung von "Ask" (OR 3.28, 95% KI 1.13-9.53) durch die Ärzte und die Sechsmonats-Abstinenzraten (OR 2.70, 95% KI 1.24-5.84) waren in der Studiengruppe im multivariablen Modell signifikant höher (p<0.05). Bei "Assist" zeigte nur das univariable Modell einen signifikanten Einfluss der Schulung (OR 2.05, 95% KI 1.09-3.87). Es wurde kein signifikanter Effekt der Schulung auf die Anwendung von "Advise" festgestellt. Die Ärzte überschätzten ihre Interventionshäufigkeiten und nannten als Gründe für die Nicht-Durchführung einer Raucherentwöhnung eine wahrgenommene geringe Aufhörmotivation der Patienten und das Vorliegen einer onkologischen oder palliativen Krankheitssituation.Fazit: Eine Ärztekurzschulung zur Raucherentwöhnung in einer pneumologischen Akutklinik erhöht den Einsatz von leitlinienbasierten Raucherentwöhnungsstrategien und könnte einen positiven Effekt auf die Abstinenzraten haben.Implikationen: Die Ergebnisse zeigen, dass Krankenhaus-basierte Strategien wie Är

Published
2020

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