39 results on '"Trott E"'
Search Results
2. Mindfulness is associated with reduced barriers to exercise via decreasing psychological distress in help-seeking young adults: A cross-sectional brief report
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Dash, Sarah, Bourke, M, Parker, AG, Trott, E, Pascoe, MC, Dash, Sarah, Bourke, M, Parker, AG, Trott, E, and Pascoe, MC
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- 2021
3. Young people's attitudes towards integrating physical activity as part of mental health treatment: A cross-sectional study in youth mental health services
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Parker, AG, Trott, E, Bourke, M, Klepac Pogrmilovic, B, Dadswell, K, Craike, M, McLean, SA, Dash, Sarah, Pascoe, M, Parker, AG, Trott, E, Bourke, M, Klepac Pogrmilovic, B, Dadswell, K, Craike, M, McLean, SA, Dash, Sarah, and Pascoe, M
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- 2021
4. Mindfulness is associated with reduced barriers to exercise via decreasing psychological distress in help-seeking young adults: A cross-sectional brief report
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Dash, S, Bourke, M, Parker, AG, Trott, E, Pascoe, MC, Dash, S, Bourke, M, Parker, AG, Trott, E, and Pascoe, MC
- Abstract
AIM: Mental illness is common among young people. Exercise has benefits for mental health; however, young people experience a range of barriers to engaging in physical activity, one of which is psychological distress. Mindfulness is a modifiable factor that can reduce distress and may, in turn, reduce perceived barriers to physical activity. The aim of this work was to explore associations between dispositional mindfulness, psychological distress and barriers to engaging in physical activity. METHODS: We used cross-sectional survey data from young adults aged 15-25 years who attended youth mental health services (headspace centres). Demographic, mindfulness, exercise barriers and wellbeing data were collected. RESULTS: Mediation analysis showed that greater dispositional mindfulness reduced perceived barriers to exercise via reductions in psychological distress among 88 help-seeking young Australians. CONCLUSION: Interventions to increase dispositional mindfulness may be helpful in reducing psychological distress and lessening barriers to exercise engagement, therefore promoting mental health among young people experiencing mental health symptoms.
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- 2021
5. Quadruplet in vitro fertilization pregnancy complicated by fetal reduction and leiomyoma
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Trott, E. A., Liarakos, G., and Russell, J. B.
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- 1997
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6. Leading for the long haul: A mixed-method evaluation of the Sustainment Leadership Scale (SLS)
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Ehrhart, M., Torres, E., Green, A., Trott, E., Willging, C., Moullin, Joanna, Aarons, G., Ehrhart, M., Torres, E., Green, A., Trott, E., Willging, C., Moullin, Joanna, and Aarons, G.
- Abstract
© 2018 The Author(s). Background: Despite our progress in understanding the organizational context for implementation and specifically the role of leadership in implementation, its role in sustainment has received little attention. This paper took a mixed-method approach to examine leadership during the sustainment phase of the Exploration, Preparation, Implementation, Sustainment (EPIS) framework. Utilizing the Implementation Leadership Scale as a foundation, we sought to develop a short, practical measure of sustainment leadership that can be used for both applied and research purposes. Methods: Data for this study were collected as a part of a larger mixed-method study of evidence-based intervention, SafeCare®, sustainment. Quantitative data were collected from 157 providers using web-based surveys. Confirmatory factor analysis was used to examine the factor structure of the Sustainment Leadership Scale (SLS). Qualitative data were collected from 95 providers who participated in one of 15 focus groups. A framework approach guided qualitative data analysis. Mixed-method integration was also utilized to examine convergence of quantitative and qualitative findings. Results: Confirmatory factor analysis supported the a priori higher order factor structure of the SLS with subscales indicating a single higher order sustainment leadership factor. The SLS demonstrated excellent internal consistency reliability. Qualitative analyses offered support for the dimensions of sustainment leadership captured by the quantitative measure, in addition to uncovering a fifth possible factor, available leadership. Conclusions: This study found qualitative and quantitative support for the pragmatic SLS measure. The SLS can be used for assessing leadership of first-level leaders to understand how staff perceive leadership during sustainment and to suggest areas where leaders could direct more attention in order to increase the likelihood that EBIs are institutionalized into the normal f
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- 2018
7. Mental Health Disorder Prevalence Trends In Germany: A Longitudinal Analysis
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Schlander, M, primary, Schwarz, O, additional, Trott, E, additional, and Banaschewski, T, additional
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- 2015
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8. Lineare Polarisation der Röntgen-Bremsstrahlung dünner Antikathoden
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Scheer, M., Trott, E., and Zahs, G.
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- 1968
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9. Parametric relationships of factors affecting maintainability of long duration manned space flights.
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Jennings, H. A and Trott, E. P
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Space Vehicles - Abstract
MARCEP mathematical and mission simulation models to evaluate parameters affecting maintainability of long duration manned space flights
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- 1967
10. P-29.
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Plouffe, L., primary, Trott, E. A., additional, Sanal, S., additional, Sherry, R. M., additional, Stewart, K., additional, and Hansen, K. A., additional
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- 1997
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11. Leslie Armour: Metaphysician, Philosopher of Community, Idealist, Friend March 9, 1931-November 1, 2014
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Trott, E.
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- 2015
12. PMH12 - Mental Health Disorder Prevalence Trends In Germany: A Longitudinal Analysis
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Schlander, M, Schwarz, O, Trott, E, and Banaschewski, T
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- 2015
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13. Parametric Relationships of Factors Affecting Maintainability of Long Duration Manned Space Flights
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Jennings, H. A., primary and Trott, E. P., additional
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- 1967
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14. Case Study - MARCEP Applied to Space Systems
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Trott, E. P., primary
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- 1967
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15. P29
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Plouffe, L., Trott, E. A., Sanal, S., Sherry, R. M., Stewart, K., and Hansen, K. A.
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- 1997
16. Cosmology intertwined: A review of the particle physics, astrophysics, and cosmology associated with the cosmological tensions and anomalies
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Elcio Abdalla, Guillermo Franco Abellán, Amin Aboubrahim, Adriano Agnello, Özgür Akarsu, Yashar Akrami, George Alestas, Daniel Aloni, Luca Amendola, Luis A. Anchordoqui, Richard I. Anderson, Nikki Arendse, Marika Asgari, Mario Ballardini, Vernon Barger, Spyros Basilakos, Ronaldo C. Batista, Elia S. Battistelli, Richard Battye, Micol Benetti, David Benisty, Asher Berlin, Paolo de Bernardis, Emanuele Berti, Bohdan Bidenko, Simon Birrer, John P. Blakeslee, Kimberly K. Boddy, Clecio R. Bom, Alexander Bonilla, Nicola Borghi, François R. Bouchet, Matteo Braglia, Thomas Buchert, Elizabeth Buckley-Geer, Erminia Calabrese, Robert R. Caldwell, David Camarena, Salvatore Capozziello, Stefano Casertano, Geoff C.-F. Chen, Jens Chluba, Angela Chen, Hsin-Yu Chen, Anton Chudaykin, Michele Cicoli, Craig J. Copi, Fred Courbin, Francis-Yan Cyr-Racine, Bożena Czerny, Maria Dainotti, Guido D'Amico, Anne-Christine Davis, Javier de Cruz Pérez, Jaume de Haro, Jacques Delabrouille, Peter B. Denton, Suhail Dhawan, Keith R. Dienes, Eleonora Di Valentino, Pu Du, Dominique Eckert, Celia Escamilla-Rivera, Agnès Ferté, Fabio Finelli, Pablo Fosalba, Wendy L. Freedman, Noemi Frusciante, Enrique Gaztañaga, William Giarè, Elena Giusarma, Adrià Gómez-Valent, Will Handley, Ian Harrison, Luke Hart, Dhiraj Kumar Hazra, Alan Heavens, Asta Heinesen, Hendrik Hildebrandt, J. Colin Hill, Natalie B. Hogg, Daniel E. Holz, Deanna C. Hooper, Nikoo Hosseininejad, Dragan Huterer, Mustapha Ishak, Mikhail M. Ivanov, Andrew H. Jaffe, In Sung Jang, Karsten Jedamzik, Raul Jimenez, Melissa Joseph, Shahab Joudaki, Marc Kamionkowski, Tanvi Karwal, Lavrentios Kazantzidis, Ryan E. Keeley, Michael Klasen, Eiichiro Komatsu, Léon V.E. Koopmans, Suresh Kumar, Luca Lamagna, Ruth Lazkoz, Chung-Chi Lee, Julien Lesgourgues, Jackson Levi Said, Tiffany R. Lewis, Benjamin L'Huillier, Matteo Lucca, Roy Maartens, Lucas M. Macri, Danny Marfatia, Valerio Marra, Carlos J.A.P. Martins, Silvia Masi, Sabino Matarrese, Arindam Mazumdar, Alessandro Melchiorri, Olga Mena, Laura Mersini-Houghton, James Mertens, Dinko Milaković, Yuto Minami, Vivian Miranda, Cristian Moreno-Pulido, Michele Moresco, David F. Mota, Emil Mottola, Simone Mozzon, Jessica Muir, Ankan Mukherjee, Suvodip Mukherjee, Pavel Naselsky, Pran Nath, Savvas Nesseris, Florian Niedermann, Alessio Notari, Rafael C. Nunes, Eoin Ó Colgáin, Kayla A. Owens, Emre Özülker, Francesco Pace, Andronikos Paliathanasis, Antonella Palmese, Supriya Pan, Daniela Paoletti, Santiago E. Perez Bergliaffa, Leandros Perivolaropoulos, Dominic W. Pesce, Valeria Pettorino, Oliver H.E. Philcox, Levon Pogosian, Vivian Poulin, Gaspard Poulot, Marco Raveri, Mark J. Reid, Fabrizio Renzi, Adam G. Riess, Vivian I. Sabla, Paolo Salucci, Vincenzo Salzano, Emmanuel N. Saridakis, Bangalore S. Sathyaprakash, Martin Schmaltz, Nils Schöneberg, Dan Scolnic, Anjan A. Sen, Neelima Sehgal, Arman Shafieloo, M.M. Sheikh-Jabbari, Joseph Silk, Alessandra Silvestri, Foteini Skara, Martin S. Sloth, Marcelle Soares-Santos, Joan Solà Peracaula, Yu-Yang Songsheng, Jorge F. Soriano, Denitsa Staicova, Glenn D. Starkman, István Szapudi, Elsa M. Teixeira, Brooks Thomas, Tommaso Treu, Emery Trott, Carsten van de Bruck, J. Alberto Vazquez, Licia Verde, Luca Visinelli, Deng Wang, Jian-Min Wang, Shao-Jiang Wang, Richard Watkins, Scott Watson, John K. Webb, Neal Weiner, Amanda Weltman, Samuel J. Witte, Radosław Wojtak, Anil Kumar Yadav, Weiqiang Yang, Gong-Bo Zhao, Miguel Zumalacárregui, Laboratoire Univers et Particules de Montpellier (LUPM), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), Laboratoire de physique de l'ENS - ENS Paris (LPENS), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité)-Département de Physique de l'ENS-PSL, École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL), Laboratoire d'Etude du Rayonnement et de la Matière en Astrophysique et Atmosphères = Laboratory for Studies of Radiation and Matter in Astrophysics and Atmospheres (LERMA), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-CY Cergy Paris Université (CY), Institut d'Astrophysique de Paris (IAP), Institut national des sciences de l'Univers (INSU - CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Centre de Recherche Astrophysique de Lyon (CRAL), École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Centre Pierre Binétruy (CPB), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-University of California [Berkeley] (UC Berkeley), University of California (UC)-University of California (UC), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Astrophysique Interprétation Modélisation (AIM (UMR7158 / UMR_E_9005 / UM_112)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Helsinki Institute of Physics, Universitat Politècnica de Catalunya. Departament de Matemàtiques, Universitat Politècnica de Catalunya. EDP - Equacions en Derivades Parcials i Aplicacions, European Commission, European Research Council, Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), Eusko Jaurlaritza, Generalitat Valenciana, Generalitat de Catalunya, Abdalla, Elcio, Abellán, Guillermo Franco, Aboubrahim, Amin, Agnello, Adriano, Akarsu, Özgür, Akrami, Yashar, Alestas, George, Aloni, Daniel, Amendola, Luca, Anchordoqui, Luis A., Anderson, Richard I., Arendse, Nikki, Asgari, Marika, Ballardini, Mario, Barger, Vernon, Basilakos, Spyro, Batista, Ronaldo C., Battistelli, Elia S., Battye, Richard, Benetti, Micol, Benisty, David, Berlin, Asher, de Bernardis, Paolo, Berti, Emanuele, Bidenko, Bohdan, Birrer, Simon, Blakeslee, John P., Boddy, Kimberly K., Bom, Clecio R., Bonilla, Alexander, Borghi, Nicola, Bouchet, François R., Braglia, Matteo, Buchert, Thoma, Buckley-Geer, Elizabeth, Calabrese, Erminia, Caldwell, Robert R., Camarena, David, Capozziello, Salvatore, Casertano, Stefano, Chen, Geoff C. -F., Chluba, Jen, Chen, Angela, Chen, Hsin-Yu, Chudaykin, Anton, Cicoli, Michele, Copi, Craig J., Courbin, Fred, Cyr-Racine, Francis-Yan, Czerny, Bożena, Dainotti, Maria, D'Amico, Guido, Davis, Anne-Christine, de Cruz Pérez, Javier, de Haro, Jaume, Delabrouille, Jacque, Denton, Peter B., Dhawan, Suhail, Dienes, Keith R., Di Valentino, Eleonora, Du, Pu, Eckert, Dominique, Escamilla-Rivera, Celia, Ferté, Agnè, Finelli, Fabio, Fosalba, Pablo, Freedman, Wendy L., Frusciante, Noemi, Gaztañaga, Enrique, Giarè, William, Giusarma, Elena, Gómez-Valent, Adrià, Handley, Will, Harrison, Ian, Hart, Luke, Hazra, Dhiraj Kumar, Heavens, Alan, Heinesen, Asta, Hildebrandt, Hendrik, Hill, J. Colin, Hogg, Natalie B., Holz, Daniel E., Hooper, Deanna C., Hosseininejad, Nikoo, Huterer, Dragan, Ishak, Mustapha, Ivanov, Mikhail M., Jaffe, Andrew H., Jang, In Sung, Jedamzik, Karsten, Jimenez, Raul, Joseph, Melissa, Joudaki, Shahab, Kamionkowski, Marc, Karwal, Tanvi, Kazantzidis, Lavrentio, Keeley, Ryan E., Klasen, Michael, Komatsu, Eiichiro, Koopmans, Léon V. E., Kumar, Suresh, Lamagna, Luca, Lazkoz, Ruth, Lee, Chung-Chi, Lesgourgues, Julien, Levi Said, Jackson, Lewis, Tiffany R., L'Huillier, Benjamin, Lucca, Matteo, Maartens, Roy, Macri, Lucas M., Marfatia, Danny, Marra, Valerio, Martins, Carlos J. A. P., Masi, Silvia, Matarrese, Sabino, Mazumdar, Arindam, Melchiorri, Alessandro, Mena, Olga, Mersini-Houghton, Laura, Mertens, Jame, Milaković, Dinko, Minami, Yuto, Miranda, Vivian, Moreno-Pulido, Cristian, Moresco, Michele, Mota, David F., Mottola, Emil, Mozzon, Simone, Muir, Jessica, Mukherjee, Ankan, Mukherjee, Suvodip, Naselsky, Pavel, Nath, Pran, Nesseris, Savva, Niedermann, Florian, Notari, Alessio, Nunes, Rafael C., Ó Colgáin, Eoin, Owens, Kayla A., Özülker, Emre, Pace, Francesco, Paliathanasis, Androniko, Palmese, Antonella, Pan, Supriya, Paoletti, Daniela, Perez Bergliaffa, Santiago E., Perivolaropoulos, Leandro, Pesce, Dominic W., Pettorino, Valeria, Philcox, Oliver H. E., Pogosian, Levon, Poulin, Vivian, Poulot, Gaspard, Raveri, Marco, Reid, Mark J., Renzi, Fabrizio, Riess, Adam G., Sabla, Vivian I., Salucci, Paolo, Salzano, Vincenzo, Saridakis, Emmanuel N., Sathyaprakash, Bangalore S., Schmaltz, Martin, Schöneberg, Nil, Scolnic, Dan, Sen, Anjan A., Sehgal, Neelima, Shafieloo, Arman, Sheikh-Jabbari, M. M., Silk, Joseph, Silvestri, Alessandra, Skara, Foteini, Sloth, Martin S., Soares-Santos, Marcelle, Solà Peracaula, Joan, Songsheng, Yu-Yang, Soriano, Jorge F., Staicova, Denitsa, Starkman, Glenn D., Szapudi, István, Teixeira, Elsa M., Thomas, Brook, Treu, Tommaso, Trott, Emery, van de Bruck, Carsten, Vazquez, J. Alberto, Verde, Licia, Visinelli, Luca, Wang, Deng, Wang, Jian-Min, Wang, Shao-Jiang, Watkins, Richard, Watson, Scott, Webb, John K., Weiner, Neal, Weltman, Amanda, Witte, Samuel J., Wojtak, Radosław, Yadav, Anil Kumar, Yang, Weiqiang, Zhao, Gong-Bo, Zumalacárregui, Miguel, Abdalla E., Abellan G.F., Aboubrahim A., Agnello A., Akarsu O., Akrami Y., Alestas G., Aloni D., Amendola L., Anchordoqui L.A., Anderson R.I., Arendse N., Asgari M., Ballardini M., Barger V., Basilakos S., Batista R.C., Battistelli E.S., Battye R., Benetti M., Benisty D., Berlin A., de Bernardis P., Berti E., Bidenko B., Birrer S., Blakeslee J.P., Boddy K.K., Bom C.R., Bonilla A., Borghi N., Bouchet F.R., Braglia M., Buchert T., Buckley-Geer E., Calabrese E., Caldwell R.R., Camarena D., Capozziello S., Casertano S., Chen G.C.-F., Chluba J., Chen A., Chen H.-Y., Chudaykin A., Cicoli M., Copi C.J., Courbin F., Cyr-Racine F.-Y., Czerny B., Dainotti M., D'Amico G., Davis A.-C., de Cruz Perez J., de Haro J., Delabrouille J., Denton P.B., Dhawan S., Dienes K.R., Di Valentino E., Du P., Eckert D., Escamilla-Rivera C., Ferte A., Finelli F., Fosalba P., Freedman W.L., Frusciante N., Gaztanaga E., Giare W., Giusarma E., Gomez-Valent A., Handley W., Harrison I., Hart L., Hazra D.K., Heavens A., Heinesen A., Hildebrandt H., Hill J.C., Hogg N.B., Holz D.E., Hooper D.C., Hosseininejad N., Huterer D., Ishak M., Ivanov M.M., Jaffe A.H., Jang I.S., Jedamzik K., Jimenez R., Joseph M., Joudaki S., Kamionkowski M., Karwal T., Kazantzidis L., Keeley R.E., Klasen M., Komatsu E., Koopmans L.V.E., Kumar S., Lamagna L., Lazkoz R., Lee C.-C., Lesgourgues J., Levi Said J., Lewis T.R., L'Huillier B., Lucca M., Maartens R., Macri L.M., Marfatia D., Marra V., Martins C.J.A.P., Masi S., Matarrese S., Mazumdar A., Melchiorri A., Mena O., Mersini-Houghton L., Mertens J., Milakovic D., Minami Y., Miranda V., Moreno-Pulido C., Moresco M., Mota D.F., Mottola E., Mozzon S., Muir J., Mukherjee A., Mukherjee S., Naselsky P., Nath P., Nesseris S., Niedermann F., Notari A., Nunes R.C., O Colgain E., Owens K.A., Ozulker E., Pace F., Paliathanasis A., Palmese A., Pan S., Paoletti D., Perez Bergliaffa S.E., Perivolaropoulos L., Pesce D.W., Pettorino V., Philcox O.H.E., Pogosian L., Poulin V., Poulot G., Raveri M., Reid M.J., Renzi F., Riess A.G., Sabla V.I., Salucci P., Salzano V., Saridakis E.N., Sathyaprakash B.S., Schmaltz M., Schoneberg N., Scolnic D., Sen A.A., Sehgal N., Shafieloo A., Sheikh-Jabbari M.M., Silk J., Silvestri A., Skara F., Sloth M.S., Soares-Santos M., Sola Peracaula J., Songsheng Y.-Y., Soriano J.F., Staicova D., Starkman G.D., Szapudi I., Teixeira E.M., Thomas B., Treu T., Trott E., van de Bruck C., Vazquez J.A., Verde L., Visinelli L., Wang D., Wang J.-M., Wang S.-J., Watkins R., Watson S., Webb J.K., Weiner N., Weltman A., Witte S.J., Wojtak R., Yadav A.K., Yang W., Zhao G.-B., and Zumalacarregui M.
- Subjects
Planck ,cosmological model ,Cosmology and Nongalactic Astrophysics (astro-ph.CO) ,FOS: Physical sciences ,Física::Astronomia i astrofísica::Cosmologia i cosmogonia [Àrees temàtiques de la UPC] ,anomaly ,Astrophysics::Cosmology and Extragalactic Astrophysics ,cosmic background radiation ,Gamma ray bursts ,large-scale structure ,Gravitational waves ,NO ,High Energy Physics - Phenomenology (hep-ph) ,gravitation: lens ,Cosmic physics ,energy: density ,fine-structure constant ,structure ,dark energy survey ,Cosmologia ,Hubble constant ,matter: energy ,new physics ,PE9_14 ,large-angle correlations ,Astrophysics -- Mathematical models ,Astronomy and Astrophysics ,universal rotation curve ,tension ,oscillation spectroscopic survey ,115 Astronomy, Space science ,redshift ,Cosmology, astrophysics, cosmological tensions ,Cosmology ,High Energy Physics - Phenomenology ,microwave-anisotropy-probe ,calibration: geometrical ,Dark matter (Astronomy) ,Space and Planetary Science ,[PHYS.HPHE]Physics [physics]/High Energy Physics - Phenomenology [hep-ph] ,matter power spectrum ,baryon acoustic-oscillations ,hubble-space-telescope ,[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph] ,statistical ,Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
E. Abdalla, G. F. Abellán, A. Aboubrahim et al., The standard Λ Cold Dark Matter (ΛCDM) cosmological model provides a good description of a wide range of astrophysical and cosmological data. However, there are a few big open questions that make the standard model look like an approximation to a more realistic scenario yet to be found. In this paper, we list a few important goals that need to be addressed in the next decade, taking into account the current discordances between the different cosmological probes, such as the disagreement in the value of the Hubble constant H0, the σ8–S8 tension, and other less statistically significant anomalies. While these discordances can still be in part the result of systematic errors, their persistence after several years of accurate analysis strongly hints at cracks in the standard cosmological scenario and the necessity for new physics or generalisations beyond the standard model. In this paper, we focus on the 5.0σ tension between the Planck CMB estimate of the Hubble constant H0 and the SH0ES collaboration measurements. After showing the H0 evaluations made from different teams using different methods and geometric calibrations, we list a few interesting new physics models that could alleviate this tension and discuss how the next decade's experiments will be crucial. Moreover, we focus on the tension of the Planck CMB data with weak lensing measurements and redshift surveys, about the value of the matter energy density Ωm, and the amplitude or rate of the growth of structure (σ8, fσ8). We list a few interesting models proposed for alleviating this tension, and we discuss the importance of trying to fit a full array of data with a single model and not just one parameter at a time. Additionally, we present a wide range of other less discussed anomalies at a statistical significance level lower than the H0–S8 tensions which may also constitute hints towards new physics, and we discuss possible generic theoretical approaches that can collectively explain the non-standard nature of these signals. Finally, we give an overview of upgraded experiments and next-generation space missions and facilities on Earth that will be of crucial importance to address all these open questions., Amin Aboubrahim is supported by the BMBF under contract 05P21PMCAA and by the DFG through the Research Training Network 2149 “Strong and Weak Interactions - from Hadrons to Dark Matter”. Adriano Agnello is supported by a Villum Experiment Grant, project number 36225. Özgür Akarsu acknowledges the support by the Turkish Academy of Sciences in the scheme of the Outstanding Young Scientist Award (TÜBA-GEBİP). Yashar Akrami is supported by Richard S. Morrison Fellowship and LabEx ENS-ICFP: ANR-10-LABX-0010/ANR-10-IDEX-0001-02 PSL*. George Alestas is supported by the project “Dioni: Computing Infrastructure for Big-Data Processing and Analysis” (MIS No. 5047222) co-funded by European Union (ERDF) and Greece through Operational Program “Competitiveness, Entrepreneurship and Innovation”, NSRF 2014-2020. Luca Amendola acknowledges support from DFG project 456622116 and from the CAPES-DAAD bilateral project “Data Analysis and Model Testing in the Era of Precision Cosmology”. Luis A. Anchordoqui and Jorge F. Soriano are supported by the U.S. National Science Foundation (NSF Grant PHY-2112527). Mario Ballardini acknowledges financial support from the contract ASI/INAF for the Euclid mission n.2018-23-HH.0. Micol Benetti acknowledges the Istituto Nazionale di Fisica Nucleare (INFN), sezione di Napoli, iniziativa specifica QGSKY. David Benisty acknowledges the support the supports of the Blavatnik and the Rothschild fellowships. John Blakeslee is supported by NOIRLab, which is managed by the Association of Universities for Research in Astronomy (AURA) under a cooperative agreement with the US National Science Foundation. Thomas Buchert has received funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme (grant agreement ERC advanced grant 740021–ARTHUS, PI: Thomas Buchert). Erminia Calabrese acknowledges support from the STFC Ernest Rutherford Fellowship ST/M004856/2, STFC Consolidated Grant ST/S00033X/1 and from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme (Grant agreement No. 849169). Salvatore Capozziello acknowledges the Istituto Nazionale di Fisica Nucleare (INFN), sezione di Napoli, iniziative specifiche QGSKY and MOONLIGHT2. Javier de Cruz Pérez is supported by a FPI fellowship associated to the project FPA2016-76005-C2-1-P. Peter Denton acknowledges support from the US Department of Energy under Grant Contract DE-SC0012704. Eleonora Di Valentino is supported by a Royal Society Dorothy Hodgkin Research Fellowship. Keith R. Dienes was supported in part by the U.S. Department of Energy under Grant DE-FG02-13ER41976 / DE-SC0009913, and also by the U.S. National Science Foundation through its employee IR/D program. Celia Escamilla-Rivera is supported by DGAPA-PAPIIT UNAM Project TA100122 and acknowledges the Royal Astronomical Society as FRAS 10147 and the Cosmostatistics National Group (CosmoNag) project. Noemi Frusciante is supported by Fundação para a Ciência e a Tecnologia (FCT) through the research grants UIDB/04434/2020, UIDP/04434/2020, PTDC/FIS-OUT/29048/2017, CERN/FIS-PAR/0037/2019 and the personal FCT grant “CosmoTests – Cosmological tests of gravity theories beyond General Relativity” with ref. number CEECIND/00017/2018 and the FCT project “BEYLA–BEYond LAmbda” with ref. number PTDC/FIS-AST/0054/2021. Adrià Gómez-Valent is funded by the Instituto Nazionale di Fisica Nucleare (INFN) through the project “Dark Energy and Modified Gravity Models in the light of Low-Redshift Observations” (n. 22425/2020). Asta Heinesen has received funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme (grant agreement ERC advanced grant 740021–ARTHUS, PI: Thomas Buchert). J. Colin Hill acknowledges support from NSF grant AST-2108536. The Flatiron Institute is supported by the Simons Foundation. Mustapha Ishak acknowledges that this material is based upon work supported in part by the Department of Energy, Office of Science, under Award Number DE-SC0022184. Michael Klasen is supported by the BMBF under contract 05P21PMCAA and by the DFG through the Research Training Network 2149 “Strong and Weak Interactions - from Hadrons to Dark Matter”. Suresh Kumar gratefully acknowledges support from the Science and Engineering Research Board (SERB), Govt. of India (File No. CRG/2021/004658). Ruth Lazkoz is supported by the Spanish Ministry of Science and Innovation through research projects FIS2017-85076-P (comprising FEDER funds), and also by the Basque Government and Generalitat Valenciana through research projects GIC17/116-IT956-16 and PROMETEO/2020/079 respectively. Benjamin L'Huillier would like to acknowledge the support of the National Research Foundation of Korea (NRF-2019R1I1A1A01063740) and the support of the Korea Institute for Advanced Study (KIAS) grant funded by the government of Korea. Jackson Levi Said would like to acknowledge support from Cosmology@MALTA which is supported by the University of Malta. Roy Maartens is supported by the South African Radio Astronomy Observatory and the National Research Foundation (Grant No. 75415). Valerio Marra thanks CNPq (Brazil) and FAPES (Brazil) for partial financial support. The work of Yuto Minami was supported in part by the Japan Society for the Promotion of Science (JSPS) KAKENHI, Grants No. JP20K14497. The work of Carlos Martins was financed by FEDER—Fundo Europeu de Desenvolvimento Regional funds through the COMPETE 2020—Operational Programme for Competitiveness and Internationalisation (POCI), and by Portuguese funds through FCT - Fundação para a Ciência e a Tecnologia in the framework of the project POCI-01-0145-FEDER-028987 and PTDC/FIS-AST/28987/2017. Olga Mena is supported by the Spanish grants PID2020-113644GB-I00, PROMETEO/2019/083 and by the European ITN project HIDDeN (H2020-MSCA-ITN-2019//860881-HIDDeN). Cristian Moreno-Pulido is funded by PID2019-105614GB-C21 and FPA2016-76005-C2-1-P (MINECO, Spain), 2017-SGR-929 (Generalitat de Catalunya) and CEX2019-000918-M (ICCUB) and partially supported by the fellowship 2019 FI_B 00351. Michele Moresco acknowledges support from MIUR, PRIN 2017 (grant 20179ZF5KS) and grants ASI n.I/023/12/0 and ASI n.2018-23-HH.0. Suvodip Mukherjee is supported by the Simons Foundation. Research at Perimeter Institute is supported in part by the Government of Canada through the Department of Innovation, Science and Economic Development and by the Province of Ontario through the Ministry of Colleges and Universities. Pran Nath is supported in part by the NSF Grant PHY-1913328. Savvas Nesseris acknowledges support from the Research Project No. PGC2018-094773-B-C32 and the Centro de Excelencia Severo Ochoa Program No. CEX2020-001007-S. Rafael Nunes acknowledges support from the Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP, São Paulo Research Foundation) under the project No. 2018/18036-5. Eoin Ó Colgáin was supported by the National Research Foundation of Korea grant funded by the Korea government (MSIT) (NRF-2020R1A2C1102899). Supriya Pan acknowledges the financial supports from the Science and Engineering Research Board, Govt. of India, under Mathematical Research Impact-Centric Support Scheme (File No. MTR/2018/000940) and The Department of Science and Technology (DST), Govt. of India, under the Scheme “Fund for Improvement of S&T Infrastructure (FIST)” [File No. SR/FST/MS-I/2019/41]. Santiago E. Perez Bergliaffa acknowledges partial support from Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)- Código de Financiamento 001, and Universidade do Estado do Rio de Janeiro (Brazil). Leandros Perivolaropoulos acknowledges support by the Hellenic Foundation for Research and Innovation (H.F.R.I.), under the “First call for H.F.R.I. Research Projects to support Faculty members and Researchers and the procurement of high-cost research equipment Grant” (Project Number: 789). Fabrizio Renzi is supported by the NWO and the Dutch Ministry of Education, Culture and Science (OCW), and from the D-ITP consortium, a program of the NWO that is funded by the OCW. Nils Schöneberg acknowledges the support of the following Maria de Maetzu fellowship grant: Esta publicación es parte de la ayuda CEX2019-000918-M, financiado por MCIN/AEI/10.13039/501100011033. Anjan A Sen acknowledges the funding from SERB, Govt of India under the research grants no: CRG/2020/004347 and MTR/20l9/000599. Arman Shafieloo would like to acknowledge the support by National Research Foundation of Korea NRF-2021M3F7A1082053, and the support of the Korea Institute for Advanced Study (KIAS) grant funded by the government of Korea. M.M. Sheikh-Jabbari acknowledges the support by SarAmadan grant No. ISEF/M/400122. Joan Solà Peracaula is funded by PID2019-105614GB-C21 and FPA2016-76005-C2-1-P (MINECO, Spain), 2017-SGR-929 (Generalitat de Catalunya), CEX2019-000918-M (ICCUB) and also partially supported by the COST Association Action CA18108 “Quantum Gravity Phenomenology in the Multimessenger Approach (QG-MM)”. Denitsa Staicova is supported by Bulgarian NSF grant KP-06-N 38/11. Glenn Starkman is partly supported by a Department of Energy grant DESC0009946 to the particle astrophysics theory group at CWRU. Brooks Thomas is supported in part by the National Science Foundation under Grant PHY-2014104. Luca Visinelli has received support from the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement “TALeNT” No. 754496 (H2020-MSCA-COFUND-2016 FELLINI). Shao-Jiang Wang is supported by the National Key Research and Development Program of China Grant No. 2021YFC2203004, No. 2021YFA0718304, the National Natural Science Foundation of China Grant No. 12105344, and the China Manned Space Project with NO.CMS-CSST-2021-B01. Weiqiang Yang has been supported by the National Natural Science Foundation of China under Grants No. 12175096 and No. 11705079, and Liaoning Revitalization Talents Program under Grant no. XLYC1907098. Gong-Bo Zhao is supported by the National Key Basic Research and Development Program of China (No. 2018YFA0404503), NSFC Grants 11925303, 11720101004, and a grant of CAS Interdisciplinary Innovation Team.
- Published
- 2022
17. Perception of the Portrayal of Autism in Netflix's Atypical Within the Autism Community.
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Jones SC, Trott E, Gordon C, and Milne L
- Abstract
Background: Fictional portrayals of autism play a role in raising awareness, shaping knowledge, and influencing attitudes toward autism. However, the accuracy of these portrayals is a topic of debate. Limited research has been conducted with the autism community regarding their perceptions of fictional portrayals of autism. This study aimed to explore autistic people's perceptions of the accuracy, educational benefits, and impact of Atypical , a Netflix comedy drama series focused on the experiences of an autistic protagonist., Methods: Participants were 77 members of the autism community (autistic N = 65, parent/partner N = 12), recruited via social media. Participants completed a cross-sectional predominantly qualitative survey. We undertook descriptive statistical analyses on the quantitative data and used a reflexive thematic analysis approach to analyze the qualitative data., Results: The majority of participants described Sam's portrayal as accurate, emphasizing that it was accurate as one example of autism. Family members appeared more likely to perceive Atypical as having informative benefit and being likely to improve attitudes toward autism than were autistic people. The primary concerns identified were the stereotypical representation of a popular media image of autism, the lack of diversity, and the depiction of autism as a burden or challenge for the protagonist and his family., Conclusions: This study builds on previous research on the portrayal of autism in entertainment media by investigating the perception of the autism community regarding one such fictional portrayal. It identifies that for entertainment media to better represent the lived experience of autistic people and improve community understanding of autism, there is a need for increased diversity of portrayals and for the involvement of autistic people in the development and production process., Competing Interests: No competing financial interests exist., (Copyright 2023, Mary Ann Liebert, Inc., publishers.)
- Published
- 2023
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18. A multicenter study assessing survival in patients with metastatic renal cell carcinoma receiving immune checkpoint inhibitor therapy with and without cytoreductive nephrectomy.
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Gross EE, Li M, Yin M, Orcutt D, Hussey D, Trott E, Holt SK, Dwyer ER, Kramer J, Oliva K, Gore JL, Schade GR, Lin DW, Tykodi SS, Hall ET, Thompson JA, Parikh A, Yang Y, Collier KA, Miah A, Mori-Vogt S, Hinkley M, Mortazavi A, Monk P, Folefac E, Clinton SK, and Psutka SP
- Subjects
- Humans, Cytoreduction Surgical Procedures, Immune Checkpoint Inhibitors pharmacology, Immune Checkpoint Inhibitors therapeutic use, Retrospective Studies, Nephrectomy, Carcinoma, Renal Cell drug therapy, Carcinoma, Renal Cell surgery, Kidney Neoplasms drug therapy, Kidney Neoplasms surgery
- Abstract
Background: Cytoreductive nephrectomy (CN) for the treatment of metastatic renal cell carcinoma (mRCC) was called into question following the publication of the CARMENA trial. While previous retrospective studies have supported CN alongside targeted therapies, there is minimal research establishing its role in conjunction with immune checkpoint inhibitor (ICI) therapy., Objective: To evaluate the association between CN and oncological outcomes in patients with mRCC treated with immunotherapy., Materials and Methods: A multicenter retrospective cohort study of patients diagnosed with mRCC between 2000 and 2020 who were treated at the Seattle Cancer Care Alliance and The Ohio State University and who were treated with ICI systemic therapy (ST) at any point in their disease course. Overall survival (OS) was estimated using Kaplan Meier analyses. Multivariable Cox proportional hazards models evaluated associations with mortality., Results: The study cohort consisted of 367 patients (CN+ST n = 232, ST alone n = 135). Among patients undergoing CN, 30 were deferred. Median survivor follow-up was 28.4 months. ICI therapy was first-line in 28.1%, second-line in 17.4%, and third or subsequent line (3L+) in 54.5% of patients. Overall, patients who underwent CN+ST had longer median OS (56.3 months IQR 50.2-79.8) compared to the ST alone group (19.1 months IQR 12.8-23.8). Multivariable analyses demonstrated a 67% reduction in risk of all-cause mortality in patients who received CN+ST vs. ST alone (P < 0.0001). Similar results were noted when first-line ICI therapy recipients were examined as a subgroup. Upfront and deferred CN did not demonstrate significant differences in OS., Conclusions: CN was independently associated with longer OS in patients with mRCC treated with ICI in any line of therapy. Our data support consideration of CN in well selected patients with mRCC undergoing treatment with ICI., (Copyright © 2022 Elsevier Inc. All rights reserved.)
- Published
- 2023
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19. The Importance of Language in Clinical Communication and Potential Impact on Empathy.
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Trott E and Watson A
- Abstract
Competing Interests: Competing InterestsThe authors declare no competing interests.
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- 2022
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20. Is There a Role for Bedside Biopsy in the Evaluation of Acute Invasive Fungal Rhinosinusitis?
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Abuzeid WM, Trott E, Jafari A, Moe KS, and Humphreys IM
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- Biopsy, Humans, Rhinitis diagnosis, Rhinitis microbiology, Sinusitis microbiology
- Published
- 2022
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21. Mindfulness is associated with reduced barriers to exercise via decreasing psychological distress in help-seeking young adults: A cross-sectional brief report.
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Dash S, Bourke M, Parker AG, Trott E, and Pascoe MC
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- Adolescent, Australia, Cross-Sectional Studies, Exercise, Humans, Stress, Psychological psychology, Young Adult, Mindfulness, Psychological Distress
- Abstract
Aim: Mental illness is common among young people. Exercise has benefits for mental health; however, young people experience a range of barriers to engaging in physical activity, one of which is psychological distress. Mindfulness is a modifiable factor that can reduce distress and may, in turn, reduce perceived barriers to physical activity. The aim of this work was to explore associations between dispositional mindfulness, psychological distress and barriers to engaging in physical activity., Methods: We used cross-sectional survey data from young adults aged 15-25 years who attended youth mental health services (headspace centres). Demographic, mindfulness, exercise barriers and wellbeing data were collected., Results: Mediation analysis showed that greater dispositional mindfulness reduced perceived barriers to exercise via reductions in psychological distress among 88 help-seeking young Australians., Conclusion: Interventions to increase dispositional mindfulness may be helpful in reducing psychological distress and lessening barriers to exercise engagement, therefore promoting mental health among young people experiencing mental health symptoms., (© 2021 John Wiley & Sons Australia, Ltd.)
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- 2022
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22. Young people's attitudes towards integrating physical activity as part of mental health treatment: A cross-sectional study in youth mental health services.
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Parker AG, Trott E, Bourke M, Klepac Pogrmilovic B, Dadswell K, Craike M, McLean SA, Dash S, and Pascoe M
- Subjects
- Adolescent, Attitude, Cross-Sectional Studies, Exercise psychology, Humans, Mental Health, Mental Health Services
- Abstract
Introduction: Due to the significant burden associated with mental disorders that have their onset in youth, there is a critical need to improve treatments and treatment outcomes. Given the evidence for physical activity (PA) as an effective intervention for reducing depression and anxiety symptoms in young people, we examined young people's attitudes towards and acceptability of PA as part of mental health treatment, predictors of current engagement in PA and predictors of attitudes towards PA as a treatment option., Methods: Participants in this cross-sectional study were 88 young people (15-25 years) who were engaged in treatment at youth mental health services in Melbourne, Australia., Results: Young people's attitudes towards PA as a treatment option were generally positive. The acceptance of PA as a treatment option was predicted by fewer perceived barriers and more benefits to exercise, higher autonomous motivation and lower amotivation; whereas, the only significant predictor of current engagement in PA was autonomous motivation., Discussion: The integration of PA interventions within mental health treatment appears to be acceptable to young people; however, acceptance of PA as a treatment option is influenced by perceived barriers and benefits of PA and autonomous motivation. A focus on increasing autonomous motivation by enhancing the perceived value of PA and choosing preference-based, enjoyable activities may assist in addressing the complex range of factors that impact the ability of these young people to become more physically active. Addressing these factors may assist with implementing PA interventions within psychological treatments for mental disorders., (© 2021 John Wiley & Sons Australia, Ltd.)
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- 2022
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23. The Roles of System and Organizational Leadership in System-Wide Evidence-Based Intervention Sustainment: A Mixed-Method Study.
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Aarons GA, Green AE, Trott E, Willging CE, Torres EM, Ehrhart MG, and Roesch SC
- Subjects
- California, Child Health Services, Child, Preschool, Focus Groups, Health Personnel, Humans, Infant, Infant, Newborn, Program Evaluation, Qualitative Research, Attitude of Health Personnel, Caregivers education, Child Abuse prevention & control, Child Welfare, Evidence-Based Practice, Leadership, Mental Health Services, Public Health
- Abstract
If evidence-based interventions (EBIs) are not sustained, investments are wasted and public health impact is limited. Leadership has been suggested as a key determinant of implementation and sustainment; however, little empirical work has examined this factor. This mixed-methods study framed using the Exploration, Preparation, Implementation, Sustainment (EPIS) conceptual framework examines leadership in both the outer service system context and inner organizational context in eleven system-wide implementations of the same EBI across two U.S. states and 87 counties. Quantitative data at the outer context (i.e., system) and inner context (i.e., team) levels demonstrated that leadership predicted future sustainment and differentiated between sites with full, partial, or no sustainment. In the outer context positive sustainment leadership was characterized as establishing a project's mission and vision, early and continued planning for sustainment, realistic project plans, and having alternative strategies for project survival. Inner context frontline transformational leadership predicted sustainment while passive-avoidant leadership predicted non-sustainment. Qualitative results found that sustainment was associated with outer context leadership characterized by engagement in ongoing supportive EBI championing, marketing to stakeholders; persevering in these activities; taking action to institutionalize the EBI with funding, contracting, and system improvement plans; and fostering ongoing collaboration between stakeholders at state and county, and community stakeholder levels. For frontline leadership the most important activities included championing the EBI and providing practical support for service providers. There was both convergence and expansion that identified unique contributions of the quantitative and qualitative methods. Greater attention to leadership in both the outer system and inner organizational contexts is warranted to enhance EBI implementation and sustainment.
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- 2016
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24. The role of collaborations in sustaining an evidence-based intervention to reduce child neglect.
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Green AE, Trott E, Willging CE, Finn NK, Ehrhart MG, and Aarons GA
- Subjects
- Analysis of Variance, Caregivers education, Child, Child Protective Services education, Cooperative Behavior, Delivery of Health Care organization & administration, Evidence-Based Practice organization & administration, Female, Focus Groups, Health Personnel, Humans, Male, Public-Private Sector Partnerships, Rural Health, United States, Urban Health, Child Abuse prevention & control, Child Protective Services methods, Interprofessional Relations
- Abstract
Child neglect is the most prevalent form of child maltreatment and represents 79.5% of open child-welfare cases. A recent study found the evidence-based intervention (EBI) SafeCare(®) (SC) to significantly reduce child neglect recidivism rates. To fully capitalize on the effectiveness of such EBIs, service systems must engage in successful implementation and sustainment; however, little is known regarding what factors influence EBI sustainment. Collaborations among stakeholders are suggested as a means for facilitating EBI implementation and sustainment. This study combines descriptive quantitative survey data with qualitative interview and focus group findings to examine the role of collaboration within the context of public-private partnerships in 11 child welfare systems implementing SC. Participants included administrators of government child welfare systems and community-based organizations, as well as supervisors, coaches, and home visitors of the SC program. Sites were classified as fully-, partially-, and non-sustaining based on implementation fidelity. One-way analysis of variance was used to examine differences in stakeholder reported Effective Collaboration scores across fully-sustaining, partially-sustaining, and non-sustaining sites. Qualitative transcripts were analyzed via open and focused coding to identify the commonality, diversity, and complexity of collaborations involved in implementing and sustaining SC. Fully-sustaining sites reported significantly greater levels of effective collaboration than non-sustaining sites. Key themes described by SC stakeholders included shared vision, building on existing relationships, academic support, problem solving and resource sharing, and maintaining collaborations over time. Both quantitative and qualitative results converge in highlighting the importance of effective collaboration in EBI sustainment in child welfare service systems., (Copyright © 2015 Elsevier Ltd. All rights reserved.)
- Published
- 2016
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25. Long-term evaluation of safety and health-related quality of life in women with heavy menstrual bleeding treated with oral tranexamic acid.
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Muse K, Lukes AS, Gersten J, Waldbaum A, Mabey RG, and Trott E
- Subjects
- Adolescent, Adult, Antifibrinolytic Agents adverse effects, Antifibrinolytic Agents therapeutic use, Female, Humans, Middle Aged, Quality of Life, Time, Young Adult, Menorrhagia drug therapy, Tranexamic Acid adverse effects, Tranexamic Acid therapeutic use
- Abstract
Aims: A multicenter, long-term, open-label study was conducted to assess the safety and health-related quality of life (HRQoL) of an oral tranexamic acid (TA) formulation in women with cyclic heavy menstrual bleeding (HMB)., Materials & Methods: Following a screening menstrual cycle, women with a history of cyclic HMB initiated 27 cycles of treatment with TA 1.3 g administered three-times daily for up to 5 days per menstrual cycle (maximum of 15 doses). Safety was assessed by treatment-emergent adverse event (TEAE) monitoring, physical examinations, laboratory results, ophthalmologic examinations and electrocardiography. HRQoL was evaluated using both generic and HMB-specific instruments., Results: Most of the TEAEs were mild to moderate in severity and were largely considered unrelated to study treatment. The most commonly reported TEAEs among women in the intent-to-treat population (n = 723) were headache, menstrual discomfort and back pain. Improvements in generic and disease-specific HRQoL measures were evident during the first treatment cycle and were maintained throughout the 15 cycles of measurement for most domains., Conclusion: Long-term TA treatment was well tolerated and improved measures of HRQoL in women with cyclic HMB.
- Published
- 2011
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26. Dalteparin sodium injection treatment in patients with immunologic recurrent pregnancy loss.
- Author
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Trott EA and Trott AM
- Subjects
- Abortion, Habitual immunology, Adult, Female, Humans, Injections, Subcutaneous, Pregnancy, Pregnancy Trimester, First, Retrospective Studies, Abortion, Habitual drug therapy, Anticoagulants administration & dosage, Dalteparin administration & dosage, Pregnancy Complications immunology, Pregnancy Outcome
- Abstract
Dalteparin sodium injection in patients with an immunologic component to RPL resulted in an increase in compliance without any adverse early pregnancy outcomes.
- Published
- 2000
27. The use of pure follicle stimulating hormone during the luteal phase to increase success of ovulation induction in poor responders: a pilot study.
- Author
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Trott EA, Chakraborty S, and Russell JB
- Subjects
- Adult, Female, Fertilization in Vitro, Humans, Ovarian Follicle physiology, Pilot Projects, Prospective Studies, Follicle Stimulating Hormone administration & dosage, Infertility, Female drug therapy, Luteal Phase physiology, Ovarian Follicle drug effects, Ovulation Induction methods
- Published
- 1998
28. An open trial of sertraline for menopausal hot flushes: potential involvement of serotonin in vasomotor instability.
- Author
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Plouffe L Jr, Trott EA, Largoza M, and Hansen KA
- Subjects
- 1-Naphthylamine therapeutic use, Female, Humans, Retrospective Studies, Serotonin physiology, Sertraline, 1-Naphthylamine analogs & derivatives, Climacteric drug effects, Selective Serotonin Reuptake Inhibitors therapeutic use
- Published
- 1997
29. The role of p53 tumor suppressor gene and bcl-2 protooncogene in rat corpus luteum death.
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Trott EA, Plouffe L Jr, Hansen K, McDonough PG, George P, and Khan I
- Subjects
- Animals, Antibodies, Monoclonal, Blotting, Northern, Blotting, Western, DNA Fragmentation, Female, Immunosorbent Techniques, Pregnancy, Proto-Oncogene Proteins c-bcl-2 physiology, RNA, Messenger analysis, Rats, Rats, Sprague-Dawley, Tumor Suppressor Protein p53 physiology, Apoptosis genetics, Corpus Luteum cytology, Genes, bcl-2, Genes, p53
- Abstract
Objective: The purpose of this study was to find out whether the mammalian corpus luteum undergoes genetically programmed cell death as evidenced by the positive or negative expression of specific biochemical markers of apoptosis (p53 and bcl-2)., Study Design: Twenty-six immature 28-day-old female Sprague-Dawley rats were given 10 IU of pregnant mare's serum gonadotropin to induce ovulation and corpus luteum formation. Corpora lutea were collected on postovulatory days 8, 10, 12, and 14 and snap-frozen immediately. Determinations of apoptotic fragmentation of deoxyribonucleic acid were performed with use of samples radiolabeled at 3'-ends with deoxynucleotide alpha-phosphorus 32-deoxycytidine triphosphate (3000 Ci/mmol). Transcription of p53 and bcl-2 was determined by Northern blot analysis of total ribonucleic acid. Protein expression of p53 and bcl-2 was determined by Western blot analysis with a monoclonal rat antibody for p53 and a polyclonal rabbit antibody for bcl-2., Results: The nuclear fragmentation assay revealed formation of oligonucleosomes resulting in typical laddering of the deoxyribonucleic acid (corpus luteum) consistent with programmed cell death. Northern blot analysis of total ribonucleic acid prepared from immature (28-day-old) rat corpus luteum revealed the presence of a single p53 messenger ribonucleic acid transcript (2.1 kb) in all ages of corpus luteum studied from day 8 to day 14. Western blot analysis for p53 revealed a gradual reduction in p53 protein in corpus luteum from day 8 to day 12 until it became undetectable on day 14. Western blotting revealed expression of specific protein for bcl-2., Conclusions: It appears that programmed cell death, as evidenced by formation of oligonucleosomes, occurs during mammalian luteal regression. The patterns of p53 ribonucleic acid expression in the corpus luteum suggest that the protein products of p53 and bcl-2 do not act in a diametric manner to regulate programmed cell death in the corpus luteum. The current results suggest that the mechanisms leading to programmed cell death in the mammalian corpus luteum may differ considerably from those in other organ systems.
- Published
- 1997
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30. Evaluating müllerian anomalies as a cause of recurrent pregnancy loss.
- Author
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Nguyen L, Harford RI, and Trott EA
- Subjects
- Congenital Abnormalities diagnosis, Diagnostic Imaging, Female, Humans, Pregnancy, Uterine Cervical Incompetence diagnosis, Abortion, Habitual etiology, Mullerian Ducts abnormalities, Uterus abnormalities
- Published
- 1997
31. A review of the genetics of recurrent pregnancy loss.
- Author
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Trott EA, Russell JB, and Plouffe L Jr
- Subjects
- Female, Humans, Pregnancy, Recurrence, Abortion, Spontaneous genetics, Pregnancy Outcome genetics
- Abstract
The field of recurrent pregnancy loss (RPL) has seen a blossoming of investigations in the etiology and treatment of this condition over the last few years. Despite all of this activity, there remains much controversy in all aspects of the field. This ranges from discrepancies in the definition of recurrent pregnancy loss to elements in the work-up and the very existence of certain conditions for which aggressive therapeutic modalities are proposed. We will discuss the genetic component of RPL which is one of the few etiologies for RPL which has achieved near universal acceptance.
- Published
- 1996
32. Ovulation induction in clomiphene-resistant anovulatory women with normal dehydroepiandrosterone sulfate levels: beneficial effects of the addition of dexamethasone during the follicular phase.
- Author
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Trott EA, Plouffe L Jr, Hansen K, Hines R, Brann DW, and Mahesh VB
- Subjects
- Adult, Anovulation blood, Anovulation drug therapy, Clomiphene therapeutic use, Dehydroepiandrosterone blood, Dehydroepiandrosterone Sulfate, Dexamethasone therapeutic use, Dose-Response Relationship, Drug, Drug Synergism, Female, Fertility Agents, Female therapeutic use, Follicular Phase drug effects, Follicular Phase physiology, Glucocorticoids therapeutic use, Humans, Pilot Projects, Pregnancy, Pregnancy Outcome, Retrospective Studies, Anovulation physiopathology, Clomiphene pharmacology, Dehydroepiandrosterone analogs & derivatives, Dexamethasone pharmacology, Fertility Agents, Female pharmacology, Glucocorticoids pharmacology, Ovulation Induction methods
- Abstract
Objective: To evaluate the effect on ovulation of a 10-day course of dexamethasone (DEX) initiated concurrently with a 5-day course of clomiphene citrate (CC) in CC-resistant patients with normal DHEAS levels., Design: Retrospective review., Settings: Patients from the clinical practice of the authors at the Medical College of Georgia, Augusta, Georgia., Patients: Thirteen oligomenorrheic women with normal DHEAS levels who failed to ovulate on a graduated regimen of CC up to a dose of 150 mg for 5 days., Interventions: Ten-day course of DEX initiated concurrently with a 5-day course of CC; ovulation and pregnancy outcomes recorded., Main Outcome Measure: Pregnancy., Results: Eleven of 13 women had evidence of ovulation. Five clinical pregnancies were achieved., Conclusion: These initial data support improvements in follicular development with an overlapping follicular phase regimen of CC and DEX in patients with normal DHEAS levels and a previous poor response.
- Published
- 1996
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33. Premenstrual syndrome: diagnosis and treatment.
- Author
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Trott A, Trott A, and Trott E
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- Diagnosis, Differential, Female, Humans, Incidence, Prognosis, Premenstrual Syndrome diagnosis, Premenstrual Syndrome etiology, Premenstrual Syndrome physiopathology, Premenstrual Syndrome therapy
- Abstract
Premenstrual syndrome (PMS), many physicians do not believe that the disorder exists. Numerous special interest groups also dispute its existence. There is still no clear consensus about the diagnosis of PMS. It is now a diagnosable disorder which can be effectively treated. This article describes the diagnosis, clinical features, and approach to management of PMS.
- Published
- 1996
34. Major complications associated with termination of a second trimester pregnancy: a case report.
- Author
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Trott E, Ziegler W, and Levey J
- Subjects
- Adult, Female, Humans, Pregnancy, Uterine Hemorrhage diagnosis, Uterine Hemorrhage surgery, Uterine Perforation diagnosis, Uterine Perforation surgery, Abortion, Induced, Dilatation and Curettage, Intraoperative Complications, Pregnancy Trimester, Second, Uterine Hemorrhage etiology, Uterine Perforation etiology
- Abstract
Dilation and evacuation is the most common and safest means of pregnancy termination during the first and early second trimesters. The major complication is uterine perforation. This can lead to significant sequela including hemorrhage, infection, and embolism. This case illustrates how these complications present and how they can be effectively controlled with aggressive medical and surgical management. As long as the procedure is done in a setting where these problems can be addressed, dilation and evacuation remain the method of choice for first and early second trimester terminations.
- Published
- 1995
35. The Cherney incision for removal of a large pelvic mass: a case report.
- Author
-
Trott E, Welgoss J, and Trott AA
- Subjects
- Adult, Female, Humans, Surgical Procedures, Operative methods, Leiomyoma surgery, Uterine Neoplasms surgery
- Abstract
A 40-year-old woman presented with complaints due to an enlarging uterine leiomyoma. We report the first case of a Cherney incision used to facilitate removal of a huge uterine leiomyoma.
- Published
- 1994
36. Acupuncture practice in Hawaii.
- Author
-
Trott EE
- Subjects
- Ethnicity, Hawaii, Humans, Acupuncture Therapy
- Published
- 1984
37. Hypofibrinogenaemia in obstetrics.
- Author
-
TROTT EL
- Subjects
- Female, Humans, Pregnancy, Afibrinogenemia, Obstetrics, Pregnancy Complications
- Published
- 1959
38. ADVANCES IN THE HANDLING OF HAEMOLYTIC DISEASE OF THE NEWBORN.
- Author
-
GROBBELAAR BG and TROTT EL
- Subjects
- Female, Humans, Infant, Newborn, Pregnancy, Amniotic Fluid, Antibodies, Bilirubin, Blood Transfusion, Erythroblastosis, Fetal, Exchange Transfusion, Whole Blood, Rh-Hr Blood-Group System, Spectrophotometry
- Published
- 1965
39. The applications and complications of diagnostic amniocentesis.
- Author
-
Grobbelaar BG and Trott EL
- Subjects
- Abruptio Placentae etiology, Blood Transfusion, Intrauterine, Coombs Test, Erythroblastosis, Fetal mortality, Female, Fetal Death etiology, Gestational Age, Humans, Infant, Newborn, Obstetric Labor, Premature etiology, Pregnancy, Rh-Hr Blood-Group System, Amniotic Fluid analysis, Erythroblastosis, Fetal diagnosis, Pregnancy Complications diagnosis
- Published
- 1968
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