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3. Impact of diabetic ketoacidosis on outcomes in hospitalized diabetic patients with Clostridioides difficile infection: a national inpatient analysis.

Author

Polpichai, Natchaya, Saowapa, Sakditad, Wattanachayakul, Phuuwadith, Danpanichkul, Pojsakorn, Tahir, Hamza, Abdalla, Monzer, and Trongtorsak, Angkawipa

Abstract

Introduction: Diabetic ketoacidosis (DKA) is a critical diabetic emergency with life-threatening complications. The impact of DKA on hospital outcomes in diabetic patients with Clostridioides difficile infection (CDI) remains unclear. Methods: This retrospective analysis used data from the 2016 to 2020 National Inpatient Survey. Adults with diabetes and CDI were categorized into groups with and without DKA. Hospitalization characteristics, comorbidities, and clinical outcomes were compared. Primary outcomes included mortality, length of stay, and total hospital charges. Secondary outcomes included CDI complications. Multivariate logistic regression analysis was conducted, with P values ≤ 0.05 considered statistically significant. Results: Among 494,664 diabetic patients with CDI, 6130 had DKA. Patients with DKA had significantly higher total hospital charges ($194,824 vs $103,740, P < 0.001) and longer length of stay (10.14 vs 6.04 days, P < 0.001). After adjusting for confounders, DKA patients had increased odds of mortality (adjusted odds ratio [aOR] 2.07), sepsis (aOR 1.40), septic shock (aOR 1.76), cardiac arrest (aOR 3.24), vasopressor use (aOR 2.01), and mechanical ventilation (aOR 1.96) (all P < 0.001). Conclusion: The presence of DKA significantly elevates hospital burden and CDI complications in diabetic patients. These findings underscore the need for close monitoring and aggressive management of DKA in patients with concurrent CDI to improve outcomes. [ABSTRACT FROM AUTHOR]

Published
2024
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5. Impact of diabetic ketoacidosis on outcomes in hospitalized diabetic patients with Clostridioides difficileinfection: a national inpatient analysis

Author

Polpichai, Natchaya, Saowapa, Sakditad, Wattanachayakul, Phuuwadith, Danpanichkul, Pojsakorn, Tahir, Hamza, Abdalla, Monzer, and Trongtorsak, Angkawipa

Abstract

AbstractIntroductionDiabetic ketoacidosis (DKA) is a critical diabetic emergency with life-threatening complications. The impact of DKA on hospital outcomes in diabetic patients with Clostridioides difficileinfection (CDI) remains unclear.MethodsThis retrospective analysis used data from the 2016 to 2020 National Inpatient Survey. Adults with diabetes and CDI were categorized into groups with and without DKA. Hospitalization characteristics, comorbidities, and clinical outcomes were compared. Primary outcomes included mortality, length of stay, and total hospital charges. Secondary outcomes included CDI complications. Multivariate logistic regression analysis was conducted, with Pvalues ≤ 0.05 considered statistically significant.ResultsAmong 494,664 diabetic patients with CDI, 6130 had DKA. Patients with DKA had significantly higher total hospital charges ($194,824 vs $103,740, P < 0.001) and longer length of stay (10.14 vs 6.04 days, P < 0.001). After adjusting for confounders, DKA patients had increased odds of mortality (adjusted odds ratio [aOR] 2.07), sepsis (aOR 1.40), septic shock (aOR 1.76), cardiac arrest (aOR 3.24), vasopressor use (aOR 2.01), and mechanical ventilation (aOR 1.96) (all P < 0.001).ConclusionThe presence of DKA significantly elevates hospital burden and CDI complications in diabetic patients. These findings underscore the need for close monitoring and aggressive management of DKA in patients with concurrent CDI to improve outcomes.

Published
2024
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14. Impact of colon cancer on outcomes in hospitalized patients with Clostridioides difficile infection: a national inpatient analysis.

Author

Polpichai, Natchaya, Saowapa, Sakditad, Jaroenlapnopparat, Aunchalee, Wattanachayakul, Phuuwadith, Danpanichkul, Pojsakorn, Tanariyakul, Manasawee, and Trongtorsak, Angkawipa

Abstract

Clostridioides difficile infection (CDI) burdens hospitalized patients, particularly those with comorbidities. Colon cancer may worsen CDI severity and outcomes. We aimed to assess CDI outcomes in hospitalized colon cancer patients. A retrospective analysis of 2016 to 2020 National Inpatient Survey data identified adults with CDI, categorized by the presence of colon cancer. Hospitalization characteristics, comorbidities, and outcomes were compared between groups. Primary outcomes included in-hospital mortality, length of stay, and total hospital charges. The secondary outcomes were CDI complications. Multivariate logistic regression analysis was performed, with P values ≤0.05 indicating statistical significance. Among 1,436,860 CDI patients, 14,085 had colon cancer. Patients with colon cancer had a longer length of stay (10.77 vs 9.98 days; P < 0.001). After adjustment for confounders, colon cancer patients exhibited higher odds of acute peritonitis (adjusted odds ratio [aOR] 2.37; P = 0.009), bowel perforation (aOR 5.49; P < 0.001), paralytic ileus (aOR 2.12; P = 0.003), and colectomy (aOR 36.99; P < 0.001), but lower risks of mortality, sepsis, septic shock, acute kidney injury, cardiac arrest, and mechanical ventilation (all P < 0.001). Colon cancer significantly impacts CDI outcomes in hospitalized patients, highlighting the need for improved management strategies to reduce morbidity and mortality. [ABSTRACT FROM AUTHOR]

Published
2024
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19. Impact of colon cancer on outcomes in hospitalized patients with Clostridioides difficileinfection: a national inpatient analysis

Author

Polpichai, Natchaya, Saowapa, Sakditad, Jaroenlapnopparat, Aunchalee, Wattanachayakul, Phuuwadith, Danpanichkul, Pojsakorn, Tanariyakul, Manasawee, and Trongtorsak, Angkawipa

Abstract

AbstractBackground and aimClostridioides difficileinfection (CDI) burdens hospitalized patients, particularly those with comorbidities. Colon cancer may worsen CDI severity and outcomes. We aimed to assess CDI outcomes in hospitalized colon cancer patients.MethodsA retrospective analysis of 2016 to 2020 National Inpatient Survey data identified adults with CDI, categorized by the presence of colon cancer. Hospitalization characteristics, comorbidities, and outcomes were compared between groups. Primary outcomes included in-hospital mortality, length of stay, and total hospital charges. The secondary outcomes were CDI complications. Multivariate logistic regression analysis was performed, with Pvalues ≤0.05 indicating statistical significance.ResultsAmong 1,436,860 CDI patients, 14,085 had colon cancer. Patients with colon cancer had a longer length of stay (10.77 vs 9.98 days; P < 0.001). After adjustment for confounders, colon cancer patients exhibited higher odds of acute peritonitis (adjusted odds ratio [aOR] 2.37; P = 0.009), bowel perforation (aOR 5.49; P < 0.001), paralytic ileus (aOR 2.12; P = 0.003), and colectomy (aOR 36.99; P < 0.001), but lower risks of mortality, sepsis, septic shock, acute kidney injury, cardiac arrest, and mechanical ventilation (all P < 0.001).ConclusionColon cancer significantly impacts CDI outcomes in hospitalized patients, highlighting the need for improved management strategies to reduce morbidity and mortality.

Published
2024
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24. E-52 | Impact of comorbid systemic lupus erythematosus (SLE) on the in-hospital outcome among patients hospitalized for Transcatheter Aortic Valve Replacement (TAVR): Insight from the National Inpatient Sample 2020

Author

Wattanachayakul, Phuuwadith, Yanpiset, Panat, Rujirachun, Pongprueth, Malin, John, Danpanichkul, Pojsakorn, Polpichai, Natchaya, Trongtorsak, Angkawipa, Saowapa, Sakditad, Kewcharoen, Jakrin, Casipit, Bruce Adrian, Angelim, Sarah, and Amanullah, Aman

Published
2024
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26. E-50 | Impact of acute kidney injury on hospitalized obese patients undergoing Transcatheter Aortic Valve Replacement (TAVR): Insight from the National Inpatient Sample 2020

Author

Wattanachayakul, Phuuwadith, Yanpiset, Panat, Rujirachun, Pongprueth, Malin, John, Danpanichkul, Pojsakorn, Polpichai, Natchaya, Trongtorsak, Angkawipa, Saowapa, Sakditad, Kewcharoen, Jakrin, Casipit, Bruce Adrian, Rattanawong, Pattara, Angelim, Sarah, and Amanullah, Aman

Published
2024
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27. Amulet Versus Watchman Device for Left Atrial Appendage Closure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials and Propensity-Score-Matched Studies

Author

Leelaviwat, Natnicha, primary, Mekraksakit, Poemlarp, additional, Kewcharoen, Jakrin, additional, Thangjui, Sittinun, additional, Abdelnabi, Mahmoud, additional, Pertuz, Gaspar Del Rio, additional, Benjanuwattra, Juthipong, additional, and Trongtorsak, Angkawipa, additional

Published
2023
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33. ELECTRIC CARDIOVERSION VS PHARMACOLOGICAL THEN ELECTRIC CARDIOVERSION FOR NEW ONSET ATRIAL FIBRILLATION: A META-ANALYSIS

Author

Prasai, Paritosh, primary, Shrestha, Dhan, additional, Saad, Eltaib, additional, Trongtorsak, Angkawipa, additional, Adhikari, Aarya, additional, Gaire, Suman, additional, Adhikari, Pabitra, additional, Devkota, Amrit, additional, Oli, Prakash Raj, additional, Shtembari, Jurgen, additional, Sedhai, Yub Raj, additional, and Akbar, Muhammad Sikander, additional

Published
2023
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37. INFECTIVE ENDOCARDITIS PRESENTING AS POLYMORPHIC VENTRICULAR TACHYCARDIA

Author

Adhikari, Pabitra, primary, Antala, Drashti, additional, Begiashvili, Valiko, additional, Bhandari, Birat, additional, SAAD, ELTAIB, additional, Zhang, Qishuo, additional, Won, Ki Seok, additional, Gyawali, Sandesh, additional, Abdulrahman, Ahmed, additional, Akbar, Muhammad Sikander, additional, Prasai, Paritosh, additional, and Trongtorsak, Angkawipa, additional

Published
2023
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40. SEX AND OUTCOME DIFFERENCES AFTER CONTINUOUS-FLOW LEFT VENTRICULAR ASSIST DEVICE IMPLANTATIONS: A SYSTEMATIC REVIEW AND META-ANALYSIS

Author

Trongtorsak, Angkawipa, primary, Kewcharoen, Jakrin, additional, Thangjui, Sittinun, additional, Leelaviwat, Natnicha, additional, Li, Shannon, additional, Luo, Shengyuan, additional, Navaravong, Leenhapong, additional, Marinescu, Karolina, additional, Rao, Anupama, additional, Volgman, Annabelle S., additional, and Suboc, Tisha Marie, additional

Published
2023
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41. CRT-300.09 Amulet Versus Watchman Device for Left Atrial Appendage Closure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials and Propensity-Score-Matched Studies

Author

Leelaviwat, Natnicha, primary, Mekraksakit, Poemlarp, additional, Kewcharoen, Jakrin, additional, Thangjui, Sittinun, additional, Abdelnabi, Mahmoud, additional, Del Rio Pertuz, Gaspar, additional, Benjanuwattra, Juthipong, additional, and Trongtorsak, Angkawipa, additional

Published
2023
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42. Electric Cardioversion vs. Pharmacological with or without Electric Cardioversion for Stable New-Onset Atrial Fibrillation: A Systematic Review and Meta-Analysis

Author

Prasai, Paritosh, primary, Shrestha, Dhan Bahadur, additional, Saad, Eltaib, additional, Trongtorsak, Angkawipa, additional, Adhikari, Aarya, additional, Gaire, Suman, additional, Oli, Prakash Raj, additional, Shtembari, Jurgen, additional, Adhikari, Pabitra, additional, Sedhai, Yub Raj, additional, Akbar, Muhammad Sikander, additional, Elgendy, Islam Y., additional, and Shantha, Ghanshyam, additional

Published
2023
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