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5. Sphincter urinaire artificiel chez les patients présentant une incontinence urinaire après High Intensivity Focused Ultrasound Therapy

Author

Robin, D., Peyronnet, B., Bentellis, I., El-Akri, M., Cornu, J.-N., Brierre, T., Cousin, T., Gaillard, V., Poussot, B., Dupuis, H., Tricard, T., Hermieu, N., Pitout, A., Beraud, F., Chevallier, D., Bruyere, F., Biardeau, X., Monsaint, H., Corbel, L., Hermieu, J.-F., Lecoanet, P., Capon, G., Saussine, C., Gamé, X., and Léon, P.

Published
2022
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8. Oncologic surveillance after surgical treatment for clinically localized kidney cancer – time for a revision? (OroCCR N.129)

Author

Martini, A., primary, Bernhard, J.C., additional, Falagario, U.G., additional, Herman, G., additional, Geshkovska, A., additional, Khene, Z-E., additional, Audenet, F., additional, Champy, C., additional, Bruyere, F., additional, Rolland, M., additional, Waeckel, T., additional, Lorette, M., additional, Doumerc, N., additional, Surlemont, L., additional, Parier, B., additional, Tricard, T., additional, Branger, N., additional, Michel, C., additional, Fiard, G., additional, Fontenil, A., additional, Vallée, M., additional, Guillotreau, J., additional, Bigot, P., additional, and Beauval, J.B., additional

Published
2024
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9. Should patients with PIRADS 5 lesions be recommended against active surveillance? A multicenter retrospective European study

Author

Peyrottes, A., primary, Ducrot, Q., additional, Vitard, C., additional, Baudewyns, A., additional, Windisch, O., additional, Anract, J., additional, Dariane, C., additional, Tricard, T., additional, Baboudjian, M., additional, Sarkis, J., additional, Sadreux, Y., additional, Oderda, M., additional, De La Taille, A., additional, Olivier, J., additional, Brureau, L., additional, Diamand, R., additional, Rouviere, O., additional, Ruffion, A., additional, Desgrandchamps, F., additional, Roumiguie, M., additional, Ploussard, G., additional, and Fiard, G., additional

Published
2024
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13. Complete response in first-line metastatic renal cell carcinoma treated by immunotherapy with or without local treatment of residual disease

Author

Boudier, P., primary, Moinard-Butot, F., additional, Thouvenin, J., additional, Bigot, P., additional, Maillet, D., additional, Tricard, T., additional, Pierard, L., additional, Werle, P., additional, Lindner, V.R., additional, Martin, S., additional, Schuster, C., additional, Burgy, M., additional, Malouf, G., additional, Lang, H., additional, and Barthelemy, P., additional

Published
2023
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14. Associated factors for postoperative infections after urological surgery. Results from the national and multicenter TOCUS study

Author

Kutchukian, S., primary, Gondran-Tellier, B., additional, Robin, H., additional, Bigot, P., additional, Francot, M., additional, De Vergie, S., additional, Rigaud, P., additional, Chapuis, M., additional, Brureau, L., additional, Jousseaume, C., additional, Karrav, O., additional, Kosseifi, F.T., additional, Descazeaud, A., additional, Chicaud, M., additional, Asare, H-J., additional, Gaullier, M., additional, Poussot, B., additional, Tricard, T., additional, Borojeni, S., additional, Baboudjian, M., additional, Lechevallier, E., additional, Delpech, P-O., additional, Ayoub, E., additional, Ducousso, H., additional, Bernardeau, S., additional, Dinh, A., additional, Bruyère, F., additional, and Vallée, M., additional

Published
2023
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17. WHICH REVISION STRATEGY IS THE BEST IN CASE OF NON-MECHANICAL FAILURE OF MALE ARTIFICIAL URINARY SPHINCTER? A MULTICENTER STUDY

Author

Cousin, T, primary, Bentellis, I, additional, Lasri, S, additional, Taha, F, additional, Hermieu, N, additional, Boileau, A, additional, Zelmar, A, additional, Ciolek, C, additional, Dubois, A, additional, Leon, P, additional, Hermieu, J, additional, Brierre, T, additional, Gamé, X, additional, Tricard, T, additional, Saussine, C, additional, Lecoanet, P, additional, Vidart, A, additional, Bruyère, F, additional, Cornu, J, additional, Monsaint, H, additional, Biardeau, X, additional, Capon, G, additional, and Peyronnet, B, additional

Published
2023
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19. RISK FACTORS FOR URINARY ARTIFICIAL SPHINCTER EXPLANTATION IN NON-NEUROLOGICAL MALE PATIENTS: A MULTICENTER STUDY

Author

Pitout, A, primary, Bentellis, I, additional, Tricard, T, additional, El Akri, M, additional, Saussine, C, additional, Cornu, J, additional, Dupuis, H, additional, Chevallier, D, additional, Poussot, B, additional, Bertrand-Leon, P, additional, Brierre, T, additional, Cousin, T, additional, Hermieu, N, additional, Gamé, X, additional, Bruyère, F, additional, Hermieu, J, additional, Capon, G, additional, Biardeau, X, additional, Peyronnet, B, additional, and Lecoanet, P, additional

Published
2023
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27. Efficacy, safety and reoperation-free survival of artificial urinary sphincter in non neurological male patients over 75 years of age

Author

Girard, C., primary, El-Akri, M., additional, Durand, M., additional, Guérin, O., additional, Rambaud, C., additional, Cornu, J.N., additional, Brierre, T., additional, Cousin, T., additional, Gaillard, V., additional, Tricard, T., additional, Dupuis, H., additional, Hermieu, N., additional, Bertrand-Leon, P., additional, Chevallier, D., additional, Bruyere, F., additional, Biardeau, X., additional, Hermieu, J.F., additional, Lecoanet, P., additional, Capon, G., additional, Game, X., additional, Saussine, C., additional, Peyronnet, B., additional, and Bentellis, I., additional

Published
2023
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31. Efficacité et révisions des sphincters urinaires artificiels dans la population des hommes âgés de plus de 75 ans

Author

Girard, C., primary, El-Akri, M., additional, Durand, M., additional, Cornu, J., additional, Brierre, T., additional, Cousin, T., additional, Tricard, T., additional, Dupuis, H., additional, Hermieu, N., additional, Bertrand-Leon, P., additional, Chevallier, D., additional, Bruyere, F., additional, Biardeau, X., additional, Hermieu, J., additional, Lecoanet, P., additional, Capon, G., additional, Game, X., additional, Saussine, C., additional, and Bentellis, I., additional

Published
2022
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32. Facteurs prédictifs d’implantation de la neuromodulation sacrée dans les troubles de la vidange vésicale

Author

Nasri, J., primary, Al Hashimi, I., additional, Tricard, T., additional, Fleury, R., additional, Matta, I., additional, Bey, E., additional, Mesnard, B., additional, Gaillet, S., additional, Game, X., additional, Thuillier, C., additional, Chartie Kastler, E., additional, Karsenty, G., additional, Perrouin-Verbe, M., additional, Demeestere, A., additional, Wagner, L., additional, Ruffion, A., additional, Peyronnet, B., additional, Saussine, C., additional, Phe, V., additional, and Biardeau, X., additional

Published
2022
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33. Évaluation des pratiques d’évaluation de la neuromodulation sacrée dans les troubles de la vidange vésicale : une étude observationnelle multicentrique

Author

Nasri, J., primary, Al Hashimi, I., additional, Tricard, T., additional, Fleury, R., additional, Matta, I., additional, Bey, E., additional, Mesnard, B., additional, Gaillet, S., additional, Game, X., additional, Thuillier, C., additional, Chartier-Kastler, E., additional, Karsenty, G., additional, Perrouin-Verbe, M., additional, Demeestere, A., additional, Wagner, L., additional, Ruffion, A., additional, Peyronnet, B., additional, Saussine, C., additional, Phé, V., additional, and Biardeau, X., additional

Published
2022
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34. Facteurs de risque d’explantation du sphincter artificiel urinaire chez l’homme : une étude multicentrique

Author

Pitout, A., primary, Bentellis, I., additional, Tricard, T., additional, El-Akri, M., additional, Saussine, C., additional, Cornu, J., additional, Dupuis, H., additional, Chevallier, D., additional, Poussot, B., additional, Bertrand, P., additional, Bierre, T., additional, Cousin, T., additional, Hermieu, N., additional, Game, X., additional, Bruyere, F., additional, Hermieu, J., additional, Capon, G., additional, Biardeau, X., additional, Peyronnet, B., additional, and Lecoanet, P., additional

Published
2022
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35. 60 EFFICACY, SAFETY AND REOPERATIONS OF ARTIFICIAL URINARY SPHINCTER IN ELDERLY MALE PATIENTS: A LARGE MULTICENTRIC STUDY

Author

Girard, C, primary, El-Akri, M, additional, Durand, M, additional, Cornu, J, additional, Brierre, T, additional, Cousin, T, additional, Gaillard, V, additional, Tricard, T, additional, Dupuis, H, additional, Hermieu, N, additional, Bertrand-Leon, P, additional, Chevallier, D, additional, Bruyere, F, additional, Biardeau, X, additional, Hermieu, J, additional, Lecoanet, P, additional, Capon, G, additional, Game, X, additional, Saussine, C, additional, Peyronnet, B, additional, and Bentellis, I, additional

Published
2022
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37. Integrative genomics uncover mechanisms of renal medullary carcinoma transformation, microenvironment landscape and therapeutic vulnerabilities

Author

Bouarich R, Manriquez, Xiaoping Su, Rippinger M, Sakina Zaidi, Didier Surdez, Justine Gantzer, Kurtz J, Vokshi Bh, Irwin Davidson, Haller Ar, Herve Lang, Gabriel G. Malouf, Pavlos Msaouel, Helleux A, Lindner, Philippe Baltzinger, Guillaume Davidson, Tricard T, Franck Bourdeaut, Nizar M. Tannir, and Thouvenin J

Subjects
Programmed cell death, medicine.anatomical_structure, Cell, medicine, Cancer research, Promoter, SMARCB1, Biology, Enhancer, Gene, Transcription factor, Proto-oncogene tyrosine-protein kinase Src
Abstract

Renal medullary carcinoma (RMC) is an aggressive desmoplastic tumour driven by bi-allelic loss of SMARCB1, however the cell-of-origin, the oncogenic mechanism and the features of its microenvironment remain poorly understood. Using single-cell and multi-region sequencing of human RMC, we defined transformation of thick ascending limb (TAL) cells into at least three RMC cell states along an epithelial-mesenchymal gradient through a transcriptional switch involving loss of renal transcription factor TFCP2L1 and gain of a NFE2L2-associated ferroptosis resistance program. SMARCB1 re-expression in cultured RMC cells reactivates TFCP2L1 that relocates SWI/SNF from the promoters of the MYC-driven oncogenic program to the enhancers of TAL identity genes followed by ferroptotic cell death. We further show that RMC is associated with abundant M2-type macrophages and cancer-associated fibroblasts (CAFs) and we identify key regulatory cross-talks that shape this immunosuppressive microenvironment. Together our data describe the molecular events of RMC transformation and identify novel therapeutically targetable vulnerabilities. O_FIG O_LINKSMALLFIG WIDTH=200 HEIGHT=64 SRC="FIGDIR/small/462391v1_ufig1.gif" ALT="Figure 1"> View larger version (20K): org.highwire.dtl.DTLVardef@3cb5c2org.highwire.dtl.DTLVardef@1c0fec2org.highwire.dtl.DTLVardef@195a2a4org.highwire.dtl.DTLVardef@e8d250_HPS_FORMAT_FIGEXP M_FIG C_FIG

Published
2021

40. 659MO Avelumab (A) as the basis of neoadjuvant chemotherapy (NAC) regimen in platinum eligible and ineligible patients (pts) with non-metastatic muscle invasive bladder cancer (NM-MIBC)

Author

Martinez Chanza, N., primary, Carnot, A., additional, Barthelemy, P., additional, Casert, V., additional, Sautois, B., additional, Van den Brande, J., additional, Vanhaudenarde, V., additional, Staudacher, L., additional, Seront, E., additional, Culine, S., additional, Gizzi, M., additional, Gil, T., additional, Paesmans, M., additional, Kotecki, N., additional, Ignatiadis, M., additional, Albisinni, S., additional, Fantoni, J.C., additional, Tricard, T., additional, Roumeguere, T., additional, and Awada, A.H., additional

Published
2021
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42. Facteurs préopératoires associés au risque d’infections postopératoires après chirurgie urologique. Résultats de la cohorte nationale et multicentrique TOCUS

Author

Kutchukian, S., Gondran Tellier, B., Robin, H., Bigot, P., Francot, M., De vergie, S., Rigaud, J., Chapuis, M., Brureau, L., Karray, O., Kosseifi, F.T., Gaullier, M., Poussot, B., Tricard, T., Borojeni, S., Baboudjian, M., Lechevallier, E., Dinh, A., Bruyère, F., and Vallée, M.

Published
2023
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45. UP08 - Associated factors for postoperative infections after urological surgery. Results from the national and multicenter TOCUS study

Author

Kutchukian, S., Gondran-Tellier, B., Robin, H., Bigot, P., Francot, M., De Vergie, S., Rigaud, P., Chapuis, M., Brureau, L., Jousseaume, C., Karrav, O., Kosseifi, F.T., Descazeaud, A., Chicaud, M., Asare, H-J., Gaullier, M., Poussot, B., Tricard, T., Borojeni, S., Baboudjian, M., Lechevallier, E., Delpech, P-O., Ayoub, E., Ducousso, H., Bernardeau, S., Dinh, A., Bruyère, F., and Vallée, M.

Published
2023
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46. Robot-assisted cystectomy and ileal conduit for neurogenic bladder: Comparison of extracorporeal vs intracorporeal urinary diversion

Author

Mazouin, C., primary, Hubert, J., additional, Tricard, T., additional, Lecoanet, P., additional, Haudebert, C., additional, Bentellis, I., additional, Baron, P., additional, Hascoet, J., additional, Castes, C., additional, Tibi, B., additional, Pradere, B., additional, Bruyere, F., additional, Capon, G., additional, Manunta, A., additional, Saussine, C., additional, and Peyronnet, B., additional

Published
2021
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48. Outcomes of artificial urinary sphincter implantation in irradiated patients: A multicenter study

Author

Mamane, J., primary, Sanchez, S., additional, Lellouch, A.G., additional, El-Akrhi, M., additional, Cousin, T., additional, Capon, G., additional, Bentellis, I., additional, Chevallier, D., additional, Durand, M., additional, Robin, D., additional, Cornu, J-N., additional, Dupuis, H., additional, Gaillard, V., additional, Poussot, B., additional, Tricard, T., additional, Saussine, C., additional, Ruffion, A., additional, Pitout, A., additional, Lecoanet, P., additional, Hermieu, N., additional, Hermieu, J-F., additional, Peyronnet, B., additional, and Bertrand-Leon, P., additional

Published
2021
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49. Pregnancy and Delivery in Women with Lower Urinary Tract Reconstruction: A National Multicenter Retrospective Study

Author

Bey, E., Manach, Q., Peyronnet, B., Even, A., Chartier Kastler, E., Walder, R., Ruffion, A., Baron, M., Charlanes, A., Biardeau, X., Quenneville, V., Boillot, B., Duport, C., Tricard, T., Saussine, C., Gamé, X., Capon, G., Kerdraon, J., Cornu, J., Garabedian, C., Le Normand, L., Perrouin-Verbe, B., Phé, V., Perrouin-verbe, M., Hôpital Hôtel-Dieu de Nantes - Centre Hospitalier Universitaire de Nantes (Hôpital Hôtel-Dieu de Nantes - CHU de Nantes), Service d'urologie et transplantation rénales [CHU Pitié-Salpêtrière], CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service d'urologie [Rennes], Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Hôpital Pontchaillou-CHU Pontchaillou [Rennes], Dassault Aviation, Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Service de Gynécologie et Obstétrique [Hôpital de la Croix-Rousse - HCL], Hôpital de la Croix-Rousse [CHU - HCL], Hospices Civils de Lyon (HCL)-Hospices Civils de Lyon (HCL), Service d'urologie [Centre Hospitalier Lyon Sud - HCL], Centre Hospitalier Lyon Sud [CHU - HCL] (CHLS), Service d'urologie [Rouen], CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU), CHU Tenon [AP-HP], Sorbonne Université-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service d'Urologie, andrologie et transplantation rénale [CHRU Lille], Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Département Urology, Boulogne-Billancourt Hôpital, Paris, France., Service d'urologie [CHU Grenoble], Centre Hospitalier Universitaire [Grenoble] (CHU), Service d'Urologie [CHU de Dijon], Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon), Service d'Urologie [Strasbourg], CHU Strasbourg, Service d'Urologie [Toulouse], CHU Toulouse [Toulouse], service d'urologie [CHU Bordeaux], CHU Bordeaux [Bordeaux], Centre Mutualiste de Rééducation et de Réadaptation Fonctionnelles de KERPAPE [Ploemeur] (CMRRF), Centre Mutualiste de Rééducation et de Réadaptation Fonctionnelles de Kerpape, Nutrition, inflammation et dysfonctionnement de l'axe intestin-cerveau (ADEN), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institute for Research and Innovation in Biomedicine (IRIB), Normandie Université (NU)-Normandie Université (NU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM), UNIROUEN - UFR Santé (UNIROUEN UFR Santé), Normandie Université (NU)-Normandie Université (NU), Environnement périnatal et croissance - EA 4489 (EPS), Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Hôpital Saint-Jacques, Service d'Urologie [CHU Pitié-Salpêtrière], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Service d'urologie [Rennes] = Urology [Rennes], Hôpital Pontchaillou-CHU Pontchaillou [Rennes], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Département d'Urologie-Andrologie et Transplantation Rénale [CHU Toulouse], Pôle Urologie - Néphrologie - Dialyse - Transplantations - Brûlés - Chirurgie plastique - Explorations fonctionnelles et physiologiques [CHU Toulouse], and Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)

Subjects
[SDV.MHEP.UN]Life Sciences [q-bio]/Human health and pathology/Urology and Nephrology, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2020

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