829 results on '"Trembath, Richard C."'
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2. An LGR6 frameshift variant abrogates receptor expression on select leukocyte subsets and is associated with viral infections
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Akhtar, Shaheen, Anwar, Mohammad, Arciero, Elena, Asgar, Omar, Ashraf, Samina, Bidi, Saeed, Breen, Gerome, Broster, James, Chaudhary, Shabana, Chung, Raymond, Clinch, Megan, Collier, David, Colligan, Grainne, Curtis, Charles J., Deloukas, Panos, Durham, Ceri, Durrani, Faiza, Eto, Fabiola, Finer, Sarah, Gafton, Joseph, Angel Garcia, Ana Cristina, Griffiths, Chris, Harvey, Joanne, van Heel, David A., Heng, Teng, Hodgson, Sam, Huang, Qin Qin, Hurles, Matt, Hunt, Karen A, Hussain, Shapna, Islam, Kamrul, Iyer, Vivek, Jacobs, Benjamin M., Khan, Ahsan, Langenberg, Claudia, Lavery, Cath, Lee, Sang Hyuck, MacArthur, Daniel, Malik, Sidra, Malawsky, Daniel, Martin, Hilary, Mason, Dan, Mathur, Rohini, Mazid, Mohammed Bodrul, McDermott, John, Morton, Caroline, Newman, Bill, Owor, Elizabeth, Qureshi, Asma, Ramachandrappa, Shwetha, Raza, Mehru, Russell, Jessry, Safa, Nishat, Samuel, Miriam, Simpson, Michael, Solly, John, Spreckley, Marie, Stow, Daniel, Taylor, Michael, Trembath, Richard C., Tricker, Karen, Walter, Klaudia, Winckley, Caroline, Wood, Suzanne, Wright, John, Zengeya, Ishevanhu, Zöllner, Julia, Gomez, Esteban A., De Matteis, Roberta, Udomjarumanee, Palita, Munroe, Patricia B., and Dalli, Jesmond
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- 2024
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3. Defining the clinical validity of genes reported to cause pulmonary arterial hypertension
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Callejo, Emily P., Day, Kristina M., Macaya, Daniela, Maldonado-Velez, Gabriel, Archer, Stephen L., Auckland, Kathryn, Austin, Eric D., Badagliacca, Roberto, Barberà, Joan-Albert, Belge, Catharina, Bogaard, Harm Jan, Bonnet, Sébastien, Boomars, Karin A., Boucherat, Olivier, Chakinala, Murali M., Condliffe, Robin, Damico, Rachel Lynn, Delcroix, Marion, Desai, Ankit A., Doboszynska, Anna, Elliott, C. Greg, Eyries, Melanie, Escribano Subías, Maria Pilar, Gall, Henning, Ghio, Stefano, Ghofrani, Ardeschir-Hossein, Grünig, Ekkehard, Hamid, Rizwan, Harbaum, Lars, Hassoun, Paul M., Hemnes, Anna R., Hinderhofer, Katrin, Howard, Luke S., Humbert, Marc, Kiely, David G., Langleben, David, Lawrie, Allan, Loyd, Jim E., Moledina, Shahin, Montani, David, Morrell, Nichols W., Nichols, William C., Olschewski, Andrea, Olschewski, Horst, Papa, Silvia, Pauciulo, Mike W., Provencher, Steve, Quarck, Rozenn, Rhodes, Christopher J., Scelsi, Laura, Seeger, Werner, Stewart, Duncan J., Sweatt, Andrew, Swietlik, Emilia M., Treacy, Carmen, Trembath, Richard C., Tura-Ceide, Olga, Vizza, Carmine Dario, Vonk Noordegraaf, Anton, Wilkins, Martin R., Zamanian, Roham T., Zateyshchikov, Dmitry, Welch, Carrie L., Aldred, Micheala A., Balachandar, Srimmitha, Dooijes, Dennis, Eichstaedt, Christina A., Gräf, Stefan, Houweling, Arjan C., Machado, Rajiv D., Pandya, Divya, Prapa, Matina, Shaukat, Memoona, Southgate, Laura, Tenorio-Castano, Jair, and Chung, Wendy K.
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- 2023
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4. Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations
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Chen, Ming-Huei, Raffield, Laura M, Mousas, Abdou, Sakaue, Saori, Huffman, Jennifer E, Moscati, Arden, Trivedi, Bhavi, Jiang, Tao, Akbari, Parsa, Vuckovic, Dragana, Bao, Erik L, Zhong, Xue, Manansala, Regina, Laplante, Véronique, Chen, Minhui, Lo, Ken Sin, Qian, Huijun, Lareau, Caleb A, Beaudoin, Mélissa, Hunt, Karen A, Akiyama, Masato, Bartz, Traci M, Ben-Shlomo, Yoav, Beswick, Andrew, Bork-Jensen, Jette, Bottinger, Erwin P, Brody, Jennifer A, van Rooij, Frank JA, Chitrala, Kumaraswamynaidu, Cho, Kelly, Choquet, Hélène, Correa, Adolfo, Danesh, John, Di Angelantonio, Emanuele, Dimou, Niki, Ding, Jingzhong, Elliott, Paul, Esko, Tõnu, Evans, Michele K, Floyd, James S, Broer, Linda, Grarup, Niels, Guo, Michael H, Greinacher, Andreas, Haessler, Jeff, Hansen, Torben, Howson, Joanna MM, Huang, Qin Qin, Huang, Wei, Jorgenson, Eric, Kacprowski, Tim, Kähönen, Mika, Kamatani, Yoichiro, Kanai, Masahiro, Karthikeyan, Savita, Koskeridis, Fotis, Lange, Leslie A, Lehtimäki, Terho, Lerch, Markus M, Linneberg, Allan, Liu, Yongmei, Lyytikäinen, Leo-Pekka, Manichaikul, Ani, Martin, Hilary C, Matsuda, Koichi, Mohlke, Karen L, Mononen, Nina, Murakami, Yoshinori, Nadkarni, Girish N, Nauck, Matthias, Nikus, Kjell, Ouwehand, Willem H, Pankratz, Nathan, Pedersen, Oluf, Preuss, Michael, Psaty, Bruce M, Raitakari, Olli T, Roberts, David J, Rich, Stephen S, Rodriguez, Benjamin AT, Rosen, Jonathan D, Rotter, Jerome I, Schubert, Petra, Spracklen, Cassandra N, Surendran, Praveen, Tang, Hua, Tardif, Jean-Claude, Trembath, Richard C, Ghanbari, Mohsen, Völker, Uwe, Völzke, Henry, Watkins, Nicholas A, Zonderman, Alan B, Program, VA Million Veteran, Wilson, Peter WF, Li, Yun, Butterworth, Adam S, Gauchat, Jean-François, Chiang, Charleston WK, and Li, Bingshan
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Genetics ,Good Health and Well Being ,Asian People ,Genome-Wide Association Study ,HEK293 Cells ,Humans ,Interleukin-7 ,Mutation ,Missense ,Phenotype ,Polymorphism ,Single Nucleotide ,White People ,VA Million Veteran Program ,interleukin-7 ,genetic architecture ,fine-mapping ,selective sweeps ,polygenic trait score ,phenome-wide association study ,Biological Sciences ,Medical and Health Sciences ,Developmental Biology - Abstract
Most loci identified by GWASs have been found in populations of European ancestry (EUR). In trans-ethnic meta-analyses for 15 hematological traits in 746,667 participants, including 184,535 non-EUR individuals, we identified 5,552 trait-variant associations at p < 5 × 10-9, including 71 novel associations not found in EUR populations. We also identified 28 additional novel variants in ancestry-specific, non-EUR meta-analyses, including an IL7 missense variant in South Asians associated with lymphocyte count in vivo and IL-7 secretion levels in vitro. Fine-mapping prioritized variants annotated as functional and generated 95% credible sets that were 30% smaller when using the trans-ethnic as opposed to the EUR-only results. We explored the clinical significance and predictive value of trans-ethnic variants in multiple populations and compared genetic architecture and the effect of natural selection on these blood phenotypes between populations. Altogether, our results for hematological traits highlight the value of a more global representation of populations in genetic studies.
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- 2020
5. Complement genes contribute sex-biased vulnerability in diverse disorders
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Arranz, Maria J, Bakker, Steven, Bender, Stephan, Bramon, Elvira, Collier, David A, Crespo-Facorro, Benedicto, Hall, Jeremy, Iyegbe, Conrad, Jablensky, Assen V, Kahn, René S, Kalaydjieva, Luba, Lawrie, Stephen, Lewis, Cathryn M, Lin, Kuang, Linszen, Don H, Mata, Ignacio, McIntosh, Andrew M, Murray, Robin M, Ophoff, Roel A, Van Os, Jim, Powell, John, Rujescu, Dan, Walshe, Muriel, Weisbrod, Matthias, Wiersma, Durk, Donnelly, Peter, Barroso, Ines, Blackwell, Jenefer M, Brown, Matthew A, Casas, Juan P, Corvin, Aiden, Deloukas, Panos, Duncanson, Audrey, Jankowski, Janusz, Markus, Hugh S, Mathew, Christopher G, Palmer, Colin NA, Plomin, Robert, Rautanen, Anna, Sawcer, Stephen J, Trembath, Richard C, Viswanathan, Ananth C, Wood, Nicholas W, Spencer, Chris CA, Band, Gavin, Bellenguez, Céline, Freeman, Colin, Giannoulatou, Eleni, Hellenthal, Garrett, Pearson, Richard, Pirinen, Matti, Strange, Amy, Su, Zhan, Vukcevic, Damjan, Langford, Cordelia, Blackburn, Hannah, Bumpstead, Suzannah J, Dronov, Serge, Edkins, Sarah, Gillman, Matthew, Gray, Emma, Gwilliam, Rhian, Hammond, Naomi, Hunt, Sarah E, Jayakumar, Alagurevathi, Liddle, Jennifer, McCann, Owen T, Potter, Simon C, Ravindrarajah, Radhi, Ricketts, Michelle, Tashakkori-Ghanbaria, Avazeh, Waller, Matthew, Weston, Paul, Whittaker, Pamela, Widaa, Sara, and McCarthy, Mark I
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Autoimmune Disease ,Schizophrenia ,Mental Health ,Lupus ,Genetics ,Brain Disorders ,Biotechnology ,Aetiology ,2.1 Biological and endogenous factors ,Inflammatory and immune system ,Adult ,Alleles ,Complement C3 ,Complement C4 ,Female ,Genetic Predisposition to Disease ,HLA Antigens ,Haplotypes ,Humans ,Lupus Erythematosus ,Systemic ,Major Histocompatibility Complex ,Male ,Middle Aged ,Sex Characteristics ,Sjogren's Syndrome ,Young Adult ,Schizophrenia Working Group of the Psychiatric Genomics Consortium ,General Science & Technology - Abstract
Many common illnesses, for reasons that have not been identified, differentially affect men and women. For instance, the autoimmune diseases systemic lupus erythematosus (SLE) and Sjögren's syndrome affect nine times more women than men1, whereas schizophrenia affects men with greater frequency and severity relative to women2. All three illnesses have their strongest common genetic associations in the major histocompatibility complex (MHC) locus, an association that in SLE and Sjögren's syndrome has long been thought to arise from alleles of the human leukocyte antigen (HLA) genes at that locus3-6. Here we show that variation of the complement component 4 (C4) genes C4A and C4B, which are also at the MHC locus and have been linked to increased risk for schizophrenia7, generates 7-fold variation in risk for SLE and 16-fold variation in risk for Sjögren's syndrome among individuals with common C4 genotypes, with C4A protecting more strongly than C4B in both illnesses. The same alleles that increase risk for schizophrenia greatly reduce risk for SLE and Sjögren's syndrome. In all three illnesses, C4 alleles act more strongly in men than in women: common combinations of C4A and C4B generated 14-fold variation in risk for SLE, 31-fold variation in risk for Sjögren's syndrome, and 1.7-fold variation in schizophrenia risk among men (versus 6-fold, 15-fold and 1.26-fold variation in risk among women, respectively). At a protein level, both C4 and its effector C3 were present at higher levels in cerebrospinal fluid and plasma8,9 in men than in women among adults aged between 20 and 50 years, corresponding to the ages of differential disease vulnerability. Sex differences in complement protein levels may help to explain the more potent effects of C4 alleles in men, women's greater risk of SLE and Sjögren's syndrome and men's greater vulnerability to schizophrenia. These results implicate the complement system as a source of sexual dimorphism in vulnerability to diverse illnesses.
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- 2020
6. PIK3R3 is a candidate regulator of platelet count in people of Bangladeshi ancestry
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Akhtar, Shaheen, Anwar, Mohammad, Arciero, Elena, Asgar, Omar, Ashraf, Samina, Breen, Gerome, Chung, Raymond, Curtis, Charles J., Chaudhary, Shabana, Chowdhury, Maharun, Colligan, Grainne, Deloukas, Panos, Durham, Ceri, Durrani, Faiza, Eto, Fabiola, Finer, Sarah, Garcia, Ana Angel, Griffiths, Chris, Harvey, Joanne, Heng, Teng, Huang, Qin Qin, Hurles, Matt, Hunt, Karen A., Hussain, Shapna, Islam, Kamrul, Jacobs, Ben, Khan, Ahsan, Khan, Amara, Lavery, Cath, Lee, Sang Hyuck, Lerner, Robin, MacArthur, Daniel, Malawsky, Daniel, Martin, Hilary, Mason, Dan, Mazid, Mohammed Bodrul, McDermott, John, McSweeney, Sanam, Miah, Shefa, Munir, Sabrina, Newman, Bill, Owor, Elizabeth, Qureshi, Asma, Rahman, Samiha, Safa, Nishat, Solly, John, Tahmasebi, Farah, Trembath, Richard C., Tricker, Karen, Uddin, Nasir, van Heel, David A., Winckley, Caroline, Wright, John, Burley, Kate, Fitzgibbon, Lucy, van Heel, David, Vuckovic, Dragana, and Mumford, Andrew D.
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- 2023
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7. Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts
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Zhou, Wei, Kanai, Masahiro, Wu, Kuan-Han H., Rasheed, Humaira, Tsuo, Kristin, Hirbo, Jibril B., Wang, Ying, Bhattacharya, Arjun, Zhao, Huiling, Namba, Shinichi, Surakka, Ida, Wolford, Brooke N., Lo Faro, Valeria, Lopera-Maya, Esteban A., Läll, Kristi, Favé, Marie-Julie, Chapman, Sinéad B., Karjalainen, Juha, Kurki, Mitja, Mutaamba, Maasha, Partanen, Juulia J., Brumpton, Ben M., Chavan, Sameer, Chen, Tzu-Ting, Daya, Michelle, Ding, Yi, Feng, Yen-Chen A., Gignoux, Christopher R., Graham, Sarah E., Hornsby, Whitney E., Ingold, Nathan, Johnson, Ruth, Laisk, Triin, Lin, Kuang, Lv, Jun, Millwood, Iona Y., Palta, Priit, Pandit, Anita, Preuss, Michael H., Thorsteinsdottir, Unnur, Uzunovic, Jasmina, Zawistowski, Matthew, Zhong, Xue, Campbell, Archie, Crooks, Kristy, de Bock, Geertruida H., Douville, Nicholas J., Finer, Sarah, Fritsche, Lars G., Griffiths, Christopher J., Guo, Yu, Hunt, Karen A., Konuma, Takahiro, Marioni, Riccardo E., Nomdo, Jansonius, Patil, Snehal, Rafaels, Nicholas, Richmond, Anne, Shortt, Jonathan A., Straub, Peter, Tao, Ran, Vanderwerff, Brett, Barnes, Kathleen C., Boezen, Marike, Chen, Zhengming, Chen, Chia-Yen, Cho, Judy, Smith, George Davey, Finucane, Hilary K., Franke, Lude, Gamazon, Eric R., Ganna, Andrea, Gaunt, Tom R., Ge, Tian, Huang, Hailiang, Huffman, Jennifer, Koskela, Jukka T., Lajonchere, Clara, Law, Matthew H., Li, Liming, Lindgren, Cecilia M., Loos, Ruth J.F., MacGregor, Stuart, Matsuda, Koichi, Olsen, Catherine M., Porteous, David J., Shavit, Jordan A., Snieder, Harold, Trembath, Richard C., Vonk, Judith M., Whiteman, David, Wicks, Stephen J., Wijmenga, Cisca, Wright, John, Zheng, Jie, Zhou, Xiang, Awadalla, Philip, Boehnke, Michael, Cox, Nancy J., Geschwind, Daniel H., Hayward, Caroline, Hveem, Kristian, Kenny, Eimear E., Lin, Yen-Feng, Mägi, Reedik, Martin, Hilary C., Medland, Sarah E., Okada, Yukinori, Palotie, Aarno V., Pasaniuc, Bogdan, Sanna, Serena, Smoller, Jordan W., Stefansson, Kari, van Heel, David A., Walters, Robin G., Zöllner, Sebastian, Martin, Alicia R., Willer, Cristen J., Daly, Mark J., Neale, Benjamin M., Lopera, Esteban, Kerminen, Sini, Wu, Kuan-Han, Bhatta, Laxmi, Brumpton, Ben, Deelen, Patrick, Murakami, Yoshinori, Willer, Cristen, and Hirbo, Jibril
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- 2023
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8. Meta-analysis fine-mapping is often miscalibrated at single-variant resolution
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Zhou, Wei, Kanai, Masahiro, Wu, Kuan-Han H., Rasheed, Humaira, Tsuo, Kristin, Hirbo, Jibril B., Wang, Ying, Bhattacharya, Arjun, Zhao, Huiling, Namba, Shinichi, Surakka, Ida, Wolford, Brooke N., Lo Faro, Valeria, Lopera-Maya, Esteban A., Läll, Kristi, Favé, Marie-Julie, Partanen, Juulia J., Chapman, Sinéad B., Karjalainen, Juha, Kurki, Mitja, Maasha, Mutaamba, Brumpton, Ben M., Chavan, Sameer, Chen, Tzu-Ting, Daya, Michelle, Ding, Yi, Feng, Yen-Chen A., Guare, Lindsay A., Gignoux, Christopher R., Graham, Sarah E., Hornsby, Whitney E., Ingold, Nathan, Ismail, Said I., Johnson, Ruth, Laisk, Triin, Lin, Kuang, Lv, Jun, Millwood, Iona Y., Moreno-Grau, Sonia, Nam, Kisung, Palta, Priit, Pandit, Anita, Preuss, Michael H., Saad, Chadi, Setia-Verma, Shefali, Thorsteinsdottir, Unnur, Uzunovic, Jasmina, Verma, Anurag, Zawistowski, Matthew, Zhong, Xue, Afifi, Nahla, Al-Dabhani, Kawthar M., Al Thani, Asma, Bradford, Yuki, Campbell, Archie, Crooks, Kristy, de Bock, Geertruida H., Damrauer, Scott M., Douville, Nicholas J., Finer, Sarah, Fritsche, Lars G., Fthenou, Eleni, Gonzalez-Arroyo, Gilberto, Griffiths, Christopher J., Guo, Yu, Hunt, Karen A., Ioannidis, Alexander, Jansonius, Nomdo M., Konuma, Takahiro, Michael Lee, Ming Ta, Lopez-Pineda, Arturo, Matsuda, Yuta, Marioni, Riccardo E., Moatamed, Babak, Nava-Aguilar, Marco A., Numakura, Kensuke, Patil, Snehal, Rafaels, Nicholas, Richmond, Anne, Rojas-Muñoz, Agustin, Shortt, Jonathan A., Straub, Peter, Tao, Ran, Vanderwerff, Brett, Vernekar, Manvi, Veturi, Yogasudha, Barnes, Kathleen C., Boezen, Marike, Chen, Zhengming, Chen, Chia-Yen, Cho, Judy, Smith, George Davey, Finucane, Hilary K., Franke, Lude, Gamazon, Eric R., Ganna, Andrea, Gaunt, Tom R., Ge, Tian, Huang, Hailiang, Huffman, Jennifer, Katsanis, Nicholas, Koskela, Jukka T., Lajonchere, Clara, Law, Matthew H., Li, Liming, Lindgren, Cecilia M., Loos, Ruth J.F., MacGregor, Stuart, Matsuda, Koichi, Olsen, Catherine M., Porteous, David J., Shavit, Jordan A., Snieder, Harold, Takano, Tomohiro, Trembath, Richard C., Vonk, Judith M., Whiteman, David C., Wicks, Stephen J., Wijmenga, Cisca, Wright, John, Zheng, Jie, Zhou, Xiang, Awadalla, Philip, Boehnke, Michael, Bustamante, Carlos D., Cox, Nancy J., Fatumo, Segun, Geschwind, Daniel H., Hayward, Caroline, Hveem, Kristian, Kenny, Eimear E., Lee, Seunggeun, Lin, Yen-Feng, Mbarek, Hamdi, Mägi, Reedik, Martin, Hilary C., Medland, Sarah E., Okada, Yukinori, Palotie, Aarno V., Pasaniuc, Bogdan, Rader, Daniel J., Ritchie, Marylyn D., Sanna, Serena, Smoller, Jordan W., Stefansson, Kari, van Heel, David A., Walters, Robin G., Zöllner, Sebastian, Biobank of the Americas, Biobank Japan Project, BioMe, BioVU, CanPath - Ontario Health Study, China Kadoorie Biobank Collaborative Group, Colorado Center for Personalized Medicine, deCODE Genetics, Estonian Biobank, FinnGen, Generation Scotland, Genes & Health Research Team, LifeLines, Mass General Brigham Biobank, Michigan Genomics Initiative, National Biobank of Korea, Penn Medicine BioBank, Qatar Biobank, The Qskin Sun and Health Study, Taiwan Biobank, The Hunt Study, Ucla Atlas Community Health Initiative, Uganda Genome Resource, Uk Biobank, Martin, Alicia R., Willer, Cristen J., Daly, Mark J., Neale, Benjamin M., and Elzur, Roy
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- 2022
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9. Population‐based identity‐by‐descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia
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Harold, Denise, Connolly, Siobhan, Riley, Brien P, Kendler, Kenneth S, McCarthy, Shane E, McCombie, William R, Richards, Alex, Owen, Michael J, O'Donovan, Michael C, Walters, James, Donnelly, Peter, Bates, Lesley, Barroso, Ines, Blackwell, Jenefer M, Bramon, Elvira, Brown, Matthew A, Casas, Juan P, Corvin, Aiden, Deloukas, Panos, Duncanson, Audrey, Jankowski, Janusz, Markus, Hugh S, Mathew, Christopher G, Palmer, Colin NA, Plomin, Robert, Rautanen, Anna, Sawcer, Stephen J, Trembath, Richard C, Viswanathan, Ananth C, Wood, Nicholas W, Spencer, Chris CA, Band, Gavin, Bellenguez, Céline, Freeman, Colin, Hellenthal, Garrett, Giannoulatou, Eleni, Hopkins, Lucinda, Pirinen, Matti, Pearson, Richard, Strange, Amy, Su, Zhan, Vukcevic, Damjan, Langford, Cordelia, Hunt, Sarah E, Edkins, Sarah, Gwilliam, Rhian, Blackburn, Hannah, Bumpstead, Suzannah J, Dronov, Serge, Gillman, Matthew, Gray, Emma, Hammond, Naomi, Jayakumar, Alagurevathi, McCann, Owen T, Liddle, Jennifer, Potter, Simon C, Ravindrarajah, Radhi, Ricketts, Michelle, Waller, Matthew, Weston, Paul, Widaa, Sara, Whittaker, Pamela, Ripke, Stephan, Neale, Benjamin M, Walters, James TR, Farh, Kai‐How, Holmans, Peter A, Lee, Phil, Bulik‐Sullivan, Brendan, Collier, David A, Huang, Hailiang, Pers, Tune H, Agartz, Ingrid, Agerbo, Esben, Albus, Margot, Alexander, Madeline, Amin, Farooq, Bacanu, Silviu A, Begemann, Martin, Belliveau, Richard A, Bene, Judit, Bergen, Sarah E, Bevilacqua, Elizabeth, Bigdeli, Tim B, Black, Donald W, Bruggeman, Richard, Buccola, Nancy G, Buckner, Randy L, Byerley, William, Cahn, Wiepke, Cai, Guiqing, Campion, Dominique, Cantor, Rita M, Carr, Vaughan J, Carrera, Noa, Catts, Stanley V, Chambert, Kimberley D, Chan, Raymond CK, and Chan, Ronald YL
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Biological Sciences ,Genetics ,Clinical Research ,Schizophrenia ,Brain Disorders ,Human Genome ,Prevention ,Serious Mental Illness ,Mental Health ,Aetiology ,2.1 Biological and endogenous factors ,Adult ,Case-Control Studies ,Chromosome Mapping ,DNA Copy Number Variations ,Databases ,Genetic ,Exome ,Female ,Genetic Predisposition to Disease ,Genome-Wide Association Study ,Genotype ,Haplotypes ,Humans ,Male ,Middle Aged ,Risk Factors ,Sequence Analysis ,DNA ,Exome Sequencing ,GWAS ,IBD mapping ,rare variants ,Wellcome Trust Case Control Consortium 2 ,Schizophrenia Working Group of the Psychiatric Genomics Consortium ,Clinical Sciences ,Neurosciences ,Clinical sciences - Abstract
Genome-wide association studies (GWASs) are highly effective at identifying common risk variants for schizophrenia. Rare risk variants are also important contributors to schizophrenia etiology but, with the exception of large copy number variants, are difficult to detect with GWAS. Exome and genome sequencing, which have accelerated the study of rare variants, are expensive so alternative methods are needed to aid detection of rare variants. Here we re-analyze an Irish schizophrenia GWAS dataset (n = 3,473) by performing identity-by-descent (IBD) mapping followed by exome sequencing of individuals identified as sharing risk haplotypes to search for rare risk variants in coding regions. We identified 45 rare haplotypes (>1 cM) that were significantly more common in cases than controls. By exome sequencing 105 haplotype carriers, we investigated these haplotypes for functional coding variants that could be tested for association in independent GWAS samples. We identified one rare missense variant in PCNT but did not find statistical support for an association with schizophrenia in a replication analysis. However, IBD mapping can prioritize both individual samples and genomic regions for follow-up analysis but genome rather than exome sequencing may be more effective at detecting risk variants on rare haplotypes.
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- 2019
10. Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease
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Zhou, Wei, Kanai, Masahiro, Wu, Kuan-Han H., Rasheed, Humaira, Tsuo, Kristin, Hirbo, Jibril B., Wang, Ying, Bhattacharya, Arjun, Zhao, Huiling, Namba, Shinichi, Surakka, Ida, Wolford, Brooke N., Lo Faro, Valeria, Lopera-Maya, Esteban A., Läll, Kristi, Favé, Marie-Julie, Partanen, Juulia J., Chapman, Sinéad B., Karjalainen, Juha, Kurki, Mitja, Maasha, Mutaamba, Brumpton, Ben M., Chavan, Sameer, Chen, Tzu-Ting, Daya, Michelle, Ding, Yi, Feng, Yen-Chen A., Guare, Lindsay A., Gignoux, Christopher R., Graham, Sarah E., Hornsby, Whitney E., Ingold, Nathan, Ismail, Said I., Johnson, Ruth, Laisk, Triin, Lin, Kuang, Lv, Jun, Millwood, Iona Y., Moreno-Grau, Sonia, Nam, Kisung, Palta, Priit, Pandit, Anita, Preuss, Michael H., Saad, Chadi, Setia-Verma, Shefali, Thorsteinsdottir, Unnur, Uzunovic, Jasmina, Verma, Anurag, Zawistowski, Matthew, Zhong, Xue, Afifi, Nahla, Al-Dabhani, Kawthar M., Al Thani, Asma, Bradford, Yuki, Campbell, Archie, Crooks, Kristy, de Bock, Geertruida H., Damrauer, Scott M., Douville, Nicholas J., Finer, Sarah, Fritsche, Lars G., Fthenou, Eleni, Gonzalez-Arroyo, Gilberto, Griffiths, Christopher J., Guo, Yu, Hunt, Karen A., Ioannidis, Alexander, Jansonius, Nomdo M., Konuma, Takahiro, Lee, Ming Ta Michael, Lopez-Pineda, Arturo, Matsuda, Yuta, Marioni, Riccardo E., Moatamed, Babak, Nava-Aguilar, Marco A., Numakura, Kensuke, Patil, Snehal, Rafaels, Nicholas, Richmond, Anne, Rojas-Muñoz, Agustin, Shortt, Jonathan A., Straub, Peter, Tao, Ran, Vanderwerff, Brett, Vernekar, Manvi, Veturi, Yogasudha, Barnes, Kathleen C., Boezen, Marike, Chen, Zhengming, Chen, Chia-Yen, Cho, Judy, Smith, George Davey, Finucane, Hilary K., Franke, Lude, Gamazon, Eric R., Ganna, Andrea, Gaunt, Tom R., Ge, Tian, Huang, Hailiang, Huffman, Jennifer, Katsanis, Nicholas, Koskela, Jukka T., Lajonchere, Clara, Law, Matthew H., Li, Liming, Lindgren, Cecilia M., Loos, Ruth J.F., MacGregor, Stuart, Matsuda, Koichi, Olsen, Catherine M., Porteous, David J., Shavit, Jordan A., Snieder, Harold, Takano, Tomohiro, Trembath, Richard C., Vonk, Judith M., Whiteman, David C., Wicks, Stephen J., Wijmenga, Cisca, Wright, John, Zheng, Jie, Zhou, Xiang, Awadalla, Philip, Boehnke, Michael, Bustamante, Carlos D., Cox, Nancy J., Fatumo, Segun, Geschwind, Daniel H., Hayward, Caroline, Hveem, Kristian, Kenny, Eimear E., Lee, Seunggeun, Lin, Yen-Feng, Mbarek, Hamdi, Mägi, Reedik, Martin, Hilary C., Medland, Sarah E., Okada, Yukinori, Palotie, Aarno V., Pasaniuc, Bogdan, Rader, Daniel J., Ritchie, Marylyn D., Sanna, Serena, Smoller, Jordan W., Stefansson, Kari, van Heel, David A., Walters, Robin G., Zöllner, Sebastian, Martin, Alicia R., Willer, Cristen J., Daly, Mark J., and Neale, Benjamin M.
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- 2022
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11. A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids
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Ramdas, Shweta, Judd, Jonathan, Graham, Sarah E., Kanoni, Stavroula, Wang, Yuxuan, Surakka, Ida, Wenz, Brandon, Clarke, Shoa L., Chesi, Alessandra, Wells, Andrew, Bhatti, Konain Fatima, Vedantam, Sailaja, Winkler, Thomas W., Locke, Adam E., Marouli, Eirini, Zajac, Greg J.M., Wu, Kuan-Han H., Ntalla, Ioanna, Hui, Qin, Klarin, Derek, Hilliard, Austin T., Wang, Zeyuan, Xue, Chao, Thorleifsson, Gudmar, Helgadottir, Anna, Gudbjartsson, Daniel F., Holm, Hilma, Olafsson, Isleifur, Hwang, Mi Yeong, Han, Sohee, Akiyama, Masato, Sakaue, Saori, Terao, Chikashi, Kanai, Masahiro, Zhou, Wei, Brumpton, Ben M., Rasheed, Humaira, Havulinna, Aki S., Veturi, Yogasudha, Pacheco, Jennifer Allen, Rosenthal, Elisabeth A., Lingren, Todd, Feng, QiPing, Kullo, Iftikhar J., Narita, Akira, Takayama, Jun, Martin, Hilary C., Hunt, Karen A., Trivedi, Bhavi, Haessler, Jeffrey, Giulianini, Franco, Bradford, Yuki, Miller, Jason E., Campbell, Archie, Lin, Kuang, Millwood, Iona Y., Rasheed, Asif, Hindy, George, Faul, Jessica D., Zhao, Wei, Weir, David R., Turman, Constance, Huang, Hongyan, Graff, Mariaelisa, Choudhury, Ananyo, Sengupta, Dhriti, Mahajan, Anubha, Brown, Michael R., Zhang, Weihua, Yu, Ketian, Schmidt, Ellen M., Pandit, Anita, Gustafsson, Stefan, Yin, Xianyong, Luan, Jian’an, Zhao, Jing-Hua, Matsuda, Fumihiko, Jang, Hye-Mi, Yoon, Kyungheon, Medina-Gomez, Carolina, Pitsillides, Achilleas, Hottenga, Jouke Jan, Wood, Andrew R., Ji, Yingji, Gao, Zishan, Haworth, Simon, Mitchell, Ruth E., Chai, Jin Fang, Aadahl, Mette, Bjerregaard, Anne A., Yao, Jie, Manichaikul, Ani, Lee, Wen-Jane, Hsiung, Chao Agnes, Warren, Helen R., Ramirez, Julia, Bork-Jensen, Jette, Kårhus, Line L., Goel, Anuj, Sabater-Lleal, Maria, Noordam, Raymond, Mauro, Pala, Matteo, Floris, McDaid, Aaron F., Marques-Vidal, Pedro, Wielscher, Matthias, Trompet, Stella, Sattar, Naveed, Møllehave, Line T., Munz, Matthias, Zeng, Lingyao, Huang, Jianfeng, Yang, Bin, Poveda, Alaitz, Kurbasic, Azra, Schönherr, Sebastian, Forer, Lukas, Scholz, Markus, Galesloot, Tessel E., Bradfield, Jonathan P., Ruotsalainen, Sanni E., Daw, E. Warwick, Zmuda, Joseph M., Mitchell, Jonathan S., Fuchsberger, Christian, Christensen, Henry, Brody, Jennifer A., Le, Phuong, Feitosa, Mary F., Wojczynski, Mary K., Hemerich, Daiane, Preuss, Michael, Mangino, Massimo, Christofidou, Paraskevi, Verweij, Niek, Benjamins, Jan W., Engmann, Jorgen, Noah, Tsao L., Verma, Anurag, Slieker, Roderick C., Lo, Ken Sin, Zilhao, Nuno R., Kleber, Marcus E., Delgado, Graciela E., Huo, Shaofeng, Ikeda, Daisuke D., Iha, Hiroyuki, Yang, Jian, Liu, Jun, Demirkan, Ayşe, Leonard, Hampton L., Marten, Jonathan, Emmel, Carina, Schmidt, Börge, Smyth, Laura J., Cañadas-Garre, Marisa, Wang, Chaolong, Nakatochi, Masahiro, Wong, Andrew, Hutri-Kähönen, Nina, Sim, Xueling, Xia, Rui, Huerta-Chagoya, Alicia, Fernandez-Lopez, Juan Carlos, Lyssenko, Valeriya, Nongmaithem, Suraj S., Sankareswaran, Alagu, Irvin, Marguerite R., Oldmeadow, Christopher, Kim, Han-Na, Ryu, Seungho, Timmers, Paul R.H.J., Arbeeva, Liubov, Dorajoo, Rajkumar, Lange, Leslie A., Prasad, Gauri, Lorés-Motta, Laura, Pauper, Marc, Long, Jirong, Li, Xiaohui, Theusch, Elizabeth, Takeuchi, Fumihiko, Spracklen, Cassandra N., Loukola, Anu, Bollepalli, Sailalitha, Warner, Sophie C., Wang, Ya Xing, Wei, Wen B., Nutile, Teresa, Ruggiero, Daniela, Sung, Yun Ju, Chen, Shufeng, Liu, Fangchao, Yang, Jingyun, Kentistou, Katherine A., Banas, Bernhard, Morgan, Anna, Meidtner, Karina, Bielak, Lawrence F., Smith, Jennifer A., Hebbar, Prashantha, Farmaki, Aliki-Eleni, Hofer, Edith, Lin, Maoxuan, Concas, Maria Pina, Vaccargiu, Simona, van der Most, Peter J., Pitkänen, Niina, Cade, Brian E., van der Laan, Sander W., Chitrala, Kumaraswamy Naidu, Weiss, Stefan, Bentley, Amy R., Doumatey, Ayo P., Adeyemo, Adebowale A., Lee, Jong Young, Petersen, Eva R.B., Nielsen, Aneta A., Choi, Hyeok Sun, Nethander, Maria, Freitag-Wolf, Sandra, Southam, Lorraine, Rayner, Nigel W., Wang, Carol A., Lin, Shih-Yi, Wang, Jun-Sing, Couture, Christian, Lyytikäinen, Leo-Pekka, Nikus, Kjell, Cuellar-Partida, Gabriel, Vestergaard, Henrik, Hidalgo, Bertha, Giannakopoulou, Olga, Cai, Qiuyin, Obura, Morgan O., van Setten, Jessica, He, Karen Y., Tang, Hua, Terzikhan, Natalie, Shin, Jae Hun, Jackson, Rebecca D., Reiner, Alexander P., Martin, Lisa Warsinger, Chen, Zhengming, Li, Liming, Kawaguchi, Takahisa, Thiery, Joachim, Bis, Joshua C., Launer, Lenore J., Li, Huaixing, Nalls, Mike A., Raitakari, Olli T., Ichihara, Sahoko, Wild, Sarah H., Nelson, Christopher P., Campbell, Harry, Jäger, Susanne, Nabika, Toru, Al-Mulla, Fahd, Niinikoski, Harri, Braund, Peter S., Kolcic, Ivana, Kovacs, Peter, Giardoglou, Tota, Katsuya, Tomohiro, de Kleijn, Dominique, de Borst, Gert J., Kim, Eung Kweon, Adams, Hieab H.H., Ikram, M. Arfan, Zhu, Xiaofeng, Asselbergs, Folkert W., Kraaijeveld, Adriaan O., Beulens, Joline W.J., Shu, Xiao-Ou, Rallidis, Loukianos S., Pedersen, Oluf, Hansen, Torben, Mitchell, Paul, Hewitt, Alex W., Kähönen, Mika, Pérusse, Louis, Bouchard, Claude, Tönjes, Anke, Ida Chen, Yii-Der, Pennell, Craig E., Mori, Trevor A., Lieb, Wolfgang, Franke, Andre, Ohlsson, Claes, Mellström, Dan, Cho, Yoon Shin, Lee, Hyejin, Yuan, Jian-Min, Koh, Woon-Puay, Rhee, Sang Youl, Woo, Jeong-Taek, Heid, Iris M., Stark, Klaus J., Zimmermann, Martina E., Völzke, Henry, Homuth, Georg, Evans, Michele K., Zonderman, Alan B., Polasek, Ozren, Pasterkamp, Gerard, Hoefer, Imo E., Redline, Susan, Pahkala, Katja, Oldehinkel, Albertine J., Snieder, Harold, Biino, Ginevra, Schmidt, Reinhold, Schmidt, Helena, Bandinelli, Stefania, Dedoussis, George, Thanaraj, Thangavel Alphonse, Peyser, Patricia A., Kato, Norihiro, Schulze, Matthias B., Girotto, Giorgia, Böger, Carsten A., Jung, Bettina, Joshi, Peter K., Bennett, David A., De Jager, Philip L., Lu, Xiangfeng, Mamakou, Vasiliki, Brown, Morris, Caulfield, Mark J., Munroe, Patricia B., Guo, Xiuqing, Ciullo, Marina, Jonas, Jost B., Samani, Nilesh J., Kaprio, Jaakko, Pajukanta, Päivi, Tusié-Luna, Teresa, Aguilar-Salinas, Carlos A., Adair, Linda S., Bechayda, Sonny Augustin, de Silva, H. Janaka, Wickremasinghe, Ananda R., Krauss, Ronald M., Wu, Jer-Yuarn, Zheng, Wei, den Hollander, Anneke I., Bharadwaj, Dwaipayan, Correa, Adolfo, Wilson, James G., Lind, Lars, Heng, Chew-Kiat, Nelson, Amanda E., Golightly, Yvonne M., Wilson, James F., Penninx, Brenda, Kim, Hyung-Lae, Attia, John, Scott, Rodney J., Rao, D.C., Arnett, Donna K., Walker, Mark, Scott, Laura J., Koistinen, Heikki A., Chandak, Giriraj R., Mercader, Josep M., Villalpando, Clicerio Gonzalez, Orozco, Lorena, Fornage, Myriam, Tai, E. Shyong, van Dam, Rob M., Lehtimäki, Terho, Chaturvedi, Nish, Yokota, Mitsuhiro, Liu, Jianjun, Reilly, Dermot F., McKnight, Amy Jayne, Kee, Frank, Jöckel, Karl-Heinz, McCarthy, Mark I., Palmer, Colin N.A., Vitart, Veronique, Hayward, Caroline, Simonsick, Eleanor, van Duijn, Cornelia M., Jin, Zi-Bing, Lu, Fan, Hishigaki, Haretsugu, Lin, Xu, März, Winfried, Gudnason, Vilmundur, Tardif, Jean-Claude, Lettre, Guillaume, t Hart, Leen M., Elders, Petra J.M., Rader, Daniel J., Damrauer, Scott M., Kumari, Meena, Kivimaki, Mika, van der Harst, Pim, Spector, Tim D., Loos, Ruth J.F., Province, Michael A., Parra, Esteban J., Cruz, Miguel, Psaty, Bruce M., Brandslund, Ivan, Pramstaller, Peter P., Rotimi, Charles N., Christensen, Kaare, Ripatti, Samuli, Widén, Elisabeth, Hakonarson, Hakon, Grant, Struan F.A., Kiemeney, Lambertus, de Graaf, Jacqueline, Loeffler, Markus, Kronenberg, Florian, Gu, Dongfeng, Erdmann, Jeanette, Schunkert, Heribert, Franks, Paul W., Linneberg, Allan, Jukema, J. Wouter, Khera, Amit V., Männikkö, Minna, Jarvelin, Marjo-Riitta, Kutalik, Zoltan, Francesco, Cucca, Mook-Kanamori, Dennis O., Willems van Dijk, Ko, Watkins, Hugh, Strachan, David P., Grarup, Niels, Sever, Peter, Poulter, Neil, Huey-Herng Sheu, Wayne, Rotter, Jerome I., Dantoft, Thomas M., Karpe, Fredrik, Neville, Matt J., Timpson, Nicholas J., Cheng, Ching-Yu, Wong, Tien-Yin, Khor, Chiea Chuen, Li, Hengtong, Sabanayagam, Charumathi, Peters, Annette, Gieger, Christian, Hattersley, Andrew T., Pedersen, Nancy L., Magnusson, Patrik K.E., Boomsma, Dorret I., de Geus, Eco J.C., Cupples, L. Adrienne, van Meurs, Joyce B.J., Ikram, Arfan, Ghanbari, Mohsen, Gordon-Larsen, Penny, Huang, Wei, Kim, Young Jin, Tabara, Yasuharu, Wareham, Nicholas J., Langenberg, Claudia, Zeggini, Eleftheria, Tuomilehto, Jaakko, Kuusisto, Johanna, Laakso, Markku, Ingelsson, Erik, Abecasis, Goncalo, Chambers, John C., Kooner, Jaspal S., de Vries, Paul S., Morrison, Alanna C., Hazelhurst, Scott, Ramsay, Michèle, North, Kari E., Daviglus, Martha, Kraft, Peter, Martin, Nicholas G., Whitfield, John B., Abbas, Shahid, Saleheen, Danish, Walters, Robin G., Holmes, Michael V., Black, Corri, Smith, Blair H., Baras, Aris, Justice, Anne E., Buring, Julie E., Ridker, Paul M., Chasman, Daniel I., Kooperberg, Charles, Tamiya, Gen, Yamamoto, Masayuki, van Heel, David A., Trembath, Richard C., Wei, Wei-Qi, Jarvik, Gail P., Namjou, Bahram, Hayes, M. Geoffrey, Ritchie, Marylyn D., Jousilahti, Pekka, Salomaa, Veikko, Hveem, Kristian, Åsvold, Bjørn Olav, Kubo, Michiaki, Kamatani, Yoichiro, Okada, Yukinori, Murakami, Yoshinori, Kim, Bong-Jo, Thorsteinsdottir, Unnur, Stefansson, Kari, Zhang, Jifeng, Chen, Y. Eugene, Ho, Yuk-Lam, Lynch, Julie A., Tsao, Philip S., Chang, Kyong-Mi, Cho, Kelly, O'Donnell, Christopher J., Gaziano, John M., Wilson, Peter, Mohlke, Karen L., Frayling, Timothy M., Hirschhorn, Joel N., Kathiresan, Sekar, Boehnke, Michael, Struan Grant, Natarajan, Pradeep, Sun, Yan V., Morris, Andrew P., Deloukas, Panos, Peloso, Gina, Assimes, Themistocles L., Willer, Cristen J., Zhu, Xiang, and Brown, Christopher D.
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- 2022
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12. Transferability of genetic loci and polygenic scores for cardiometabolic traits in British Pakistani and Bangladeshi individuals
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Huang, Qin Qin, Sallah, Neneh, Dunca, Diana, Trivedi, Bhavi, Hunt, Karen A., Hodgson, Sam, Lambert, Samuel A., Arciero, Elena, Wright, John, Griffiths, Chris, Trembath, Richard C., Hemingway, Harry, Inouye, Michael, Finer, Sarah, van Heel, David A., Lumbers, R. Thomas, Martin, Hilary C., and Kuchenbaecker, Karoline
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- 2022
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13. Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
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Kanoni, Stavroula, Graham, Sarah E., Wang, Yuxuan, Surakka, Ida, Ramdas, Shweta, Zhu, Xiang, Clarke, Shoa L., Bhatti, Konain Fatima, Vedantam, Sailaja, Winkler, Thomas W., Locke, Adam E., Marouli, Eirini, Zajac, Greg J. M., Wu, Kuan-Han H., Ntalla, Ioanna, Hui, Qin, Klarin, Derek, Hilliard, Austin T., Wang, Zeyuan, Xue, Chao, Thorleifsson, Gudmar, Helgadottir, Anna, Gudbjartsson, Daniel F., Holm, Hilma, Olafsson, Isleifur, Hwang, Mi Yeong, Han, Sohee, Akiyama, Masato, Sakaue, Saori, Terao, Chikashi, Kanai, Masahiro, Zhou, Wei, Brumpton, Ben M., Rasheed, Humaira, Havulinna, Aki S., Veturi, Yogasudha, Pacheco, Jennifer Allen, Rosenthal, Elisabeth A., Lingren, Todd, Feng, QiPing, Kullo, Iftikhar J., Narita, Akira, Takayama, Jun, Martin, Hilary C., Hunt, Karen A., Trivedi, Bhavi, Haessler, Jeffrey, Giulianini, Franco, Bradford, Yuki, Miller, Jason E., Campbell, Archie, Lin, Kuang, Millwood, Iona Y., Rasheed, Asif, Hindy, George, Faul, Jessica D., Zhao, Wei, Weir, David R., Turman, Constance, Huang, Hongyan, Graff, Mariaelisa, Choudhury, Ananyo, Sengupta, Dhriti, Mahajan, Anubha, Brown, Michael R., Zhang, Weihua, Yu, Ketian, Schmidt, Ellen M., Pandit, Anita, Gustafsson, Stefan, Yin, Xianyong, Luan, Jian’an, Zhao, Jing-Hua, Matsuda, Fumihiko, Jang, Hye-Mi, Yoon, Kyungheon, Medina-Gomez, Carolina, Pitsillides, Achilleas, Hottenga, Jouke Jan, Wood, Andrew R., Ji, Yingji, Gao, Zishan, Haworth, Simon, Yousri, Noha A., Mitchell, Ruth E., Chai, Jin Fang, Aadahl, Mette, Bjerregaard, Anne A., Yao, Jie, Manichaikul, Ani, Hwu, Chii-Min, Hung, Yi-Jen, Warren, Helen R., Ramirez, Julia, Bork-Jensen, Jette, Kårhus, Line L., Goel, Anuj, Sabater-Lleal, Maria, Noordam, Raymond, Mauro, Pala, Matteo, Floris, McDaid, Aaron F., Marques-Vidal, Pedro, Wielscher, Matthias, Trompet, Stella, Sattar, Naveed, Møllehave, Line T., Munz, Matthias, Zeng, Lingyao, Huang, Jianfeng, Yang, Bin, Poveda, Alaitz, Kurbasic, Azra, Lamina, Claudia, Forer, Lukas, Scholz, Markus, Galesloot, Tessel E., Bradfield, Jonathan P., Ruotsalainen, Sanni E., Daw, EWarwick, Zmuda, Joseph M., Mitchell, Jonathan S., Fuchsberger, Christian, Christensen, Henry, Brody, Jennifer A., Vazquez-Moreno, Miguel, Feitosa, Mary F., Wojczynski, Mary K., Wang, Zhe, Preuss, Michael H., Mangino, Massimo, Christofidou, Paraskevi, Verweij, Niek, Benjamins, Jan W., Engmann, Jorgen, Tsao, Noah L., Verma, Anurag, Slieker, Roderick C., Lo, Ken Sin, Zilhao, Nuno R., Le, Phuong, Kleber, Marcus E., Delgado, Graciela E., Huo, Shaofeng, Ikeda, Daisuke D., Iha, Hiroyuki, Yang, Jian, Liu, Jun, Demirkan, Ayşe, Leonard, Hampton L., Marten, Jonathan, Frank, Mirjam, Schmidt, Börge, Smyth, Laura J., Cañadas-Garre, Marisa, Wang, Chaolong, Nakatochi, Masahiro, Wong, Andrew, Hutri-Kähönen, Nina, Sim, Xueling, Xia, Rui, Huerta-Chagoya, Alicia, Fernandez-Lopez, Juan Carlos, Lyssenko, Valeriya, Nongmaithem, Suraj S., Bayyana, Swati, Stringham, Heather M., Irvin, Marguerite R., Oldmeadow, Christopher, Kim, Han-Na, Ryu, Seungho, Timmers, Paul R. H. J., Arbeeva, Liubov, Dorajoo, Rajkumar, Lange, Leslie A., Prasad, Gauri, Lorés-Motta, Laura, Pauper, Marc, Long, Jirong, Li, Xiaohui, Theusch, Elizabeth, Takeuchi, Fumihiko, Spracklen, Cassandra N., Loukola, Anu, Bollepalli, Sailalitha, Warner, Sophie C., Wang, Ya Xing, Wei, Wen B., Nutile, Teresa, Ruggiero, Daniela, Sung, Yun Ju, Chen, Shufeng, Liu, Fangchao, Yang, Jingyun, Kentistou, Katherine A., Banas, Bernhard, Nardone, Giuseppe Giovanni, Meidtner, Karina, Bielak, Lawrence F., Smith, Jennifer A., Hebbar, Prashantha, Farmaki, Aliki-Eleni, Hofer, Edith, Lin, Maoxuan, Concas, Maria Pina, Vaccargiu, Simona, van der Most, Peter J., Pitkänen, Niina, Cade, Brian E., van der Laan, Sander W., Chitrala, Kumaraswamy Naidu, Weiss, Stefan, Bentley, Amy R., Doumatey, Ayo P., Adeyemo, Adebowale A., Lee, Jong Young, Petersen, Eva R. B., Nielsen, Aneta A., Choi, Hyeok Sun, Nethander, Maria, Freitag-Wolf, Sandra, Southam, Lorraine, Rayner, Nigel W., Wang, Carol A., Lin, Shih-Yi, Wang, Jun-Sing, Couture, Christian, Lyytikäinen, Leo-Pekka, Nikus, Kjell, Cuellar-Partida, Gabriel, Vestergaard, Henrik, Hidalgo, Bertha, Giannakopoulou, Olga, Cai, Qiuyin, Obura, Morgan O., van Setten, Jessica, Li, Xiaoyin, Liang, Jingjing, Tang, Hua, Terzikhan, Natalie, Shin, Jae Hun, Jackson, Rebecca D., Reiner, Alexander P., Martin, Lisa Warsinger, Chen, Zhengming, Li, Liming, Kawaguchi, Takahisa, Thiery, Joachim, Bis, Joshua C., Launer, Lenore J., Li, Huaixing, Nalls, Mike A., Raitakari, Olli T., Ichihara, Sahoko, Wild, Sarah H., Nelson, Christopher P., Campbell, Harry, Jäger, Susanne, Nabika, Toru, Al-Mulla, Fahd, Niinikoski, Harri, Braund, Peter S., Kolcic, Ivana, Kovacs, Peter, Giardoglou, Tota, Katsuya, Tomohiro, de Kleijn, Dominique, de Borst, Gert J., Kim, Eung Kweon, Adams, Hieab H. H., Ikram, M. Arfan, Zhu, Xiaofeng, Asselbergs, Folkert W., Kraaijeveld, Adriaan O., Beulens, Joline W. J., Shu, Xiao-Ou, Rallidis, Loukianos S., Pedersen, Oluf, Hansen, Torben, Mitchell, Paul, Hewitt, Alex W., Kähönen, Mika, Pérusse, Louis, Bouchard, Claude, Tönjes, Anke, Chen, Yii-Der Ida, Pennell, Craig E., Mori, Trevor A., Lieb, Wolfgang, Franke, Andre, Ohlsson, Claes, Mellström, Dan, Cho, Yoon Shin, Lee, Hyejin, Yuan, Jian-Min, Koh, Woon-Puay, Rhee, Sang Youl, Woo, Jeong-Taek, Heid, Iris M., Stark, Klaus J., Zimmermann, Martina E., Völzke, Henry, Homuth, Georg, Evans, Michele K., Zonderman, Alan B., Polasek, Ozren, Pasterkamp, Gerard, Hoefer, Imo E., Redline, Susan, Pahkala, Katja, Oldehinkel, Albertine J., Snieder, Harold, Biino, Ginevra, Schmidt, Reinhold, Schmidt, Helena, Bandinelli, Stefania, Dedoussis, George, Thanaraj, Thangavel Alphonse, Kardia, Sharon L. R., Peyser, Patricia A., Kato, Norihiro, Schulze, Matthias B., Girotto, Giorgia, Böger, Carsten A., Jung, Bettina, Joshi, Peter K., Bennett, David A., De Jager, Philip L., Lu, Xiangfeng, Mamakou, Vasiliki, Brown, Morris, Caulfield, Mark J., Munroe, Patricia B., Guo, Xiuqing, Ciullo, Marina, Jonas, Jost B., Samani, Nilesh J., Kaprio, Jaakko, Pajukanta, Päivi, Tusié-Luna, Teresa, Aguilar-Salinas, Carlos A., Adair, Linda S., Bechayda, Sonny Augustin, de Silva, H. Janaka, Wickremasinghe, Ananda R., Krauss, Ronald M., Wu, Jer-Yuarn, Zheng, Wei, Hollander, Anneke Iden, Bharadwaj, Dwaipayan, Correa, Adolfo, Wilson, James G., Lind, Lars, Heng, Chew-Kiat, Nelson, Amanda E., Golightly, Yvonne M., Wilson, James F., Penninx, Brenda, Kim, Hyung-Lae, Attia, John, Scott, Rodney J., Rao, D. C., Arnett, Donna K., Hunt, Steven C., Walker, Mark, Koistinen, Heikki A., Chandak, Giriraj R., Mercader, Josep M., Costanzo, Maria C., Jang, Dongkeun, Burtt, Noël P., Villalpando, Clicerio Gonzalez, Orozco, Lorena, Fornage, Myriam, Tai, EShyong, van Dam, Rob M., Lehtimäki, Terho, Chaturvedi, Nish, Yokota, Mitsuhiro, Liu, Jianjun, Reilly, Dermot F., McKnight, Amy Jayne, Kee, Frank, Jöckel, Karl-Heinz, McCarthy, Mark I., Palmer, Colin N. A., Vitart, Veronique, Hayward, Caroline, Simonsick, Eleanor, van Duijn, Cornelia M., Jin, Zi-Bing, Qu, Jia, Hishigaki, Haretsugu, Lin, Xu, März, Winfried, Gudnason, Vilmundur, Tardif, Jean-Claude, Lettre, Guillaume, Hart, Leen M.‘t, Elders, Petra J. M., Damrauer, Scott M., Kumari, Meena, Kivimaki, Mika, van der Harst, Pim, Spector, Tim D., Loos, Ruth J. F., Province, Michael A., Parra, Esteban J., Cruz, Miguel, Psaty, Bruce M., Brandslund, Ivan, Pramstaller, Peter P., Rotimi, Charles N., Christensen, Kaare, Ripatti, Samuli, Widén, Elisabeth, Hakonarson, Hakon, Grant, Struan F. A., Kiemeney, Lambertus A. L. M., de Graaf, Jacqueline, Loeffler, Markus, Kronenberg, Florian, Gu, Dongfeng, Erdmann, Jeanette, Schunkert, Heribert, Franks, Paul W., Linneberg, Allan, Jukema, J. Wouter, Khera, Amit V., Männikkö, Minna, Jarvelin, Marjo-Riitta, Kutalik, Zoltan, Francesco, Cucca, Mook-Kanamori, Dennis O., van Dijk, Ko Willems, Watkins, Hugh, Strachan, David P., Grarup, Niels, Sever, Peter, Poulter, Neil, Chuang, Lee-Ming, Rotter, Jerome I., Dantoft, Thomas M., Karpe, Fredrik, Neville, Matt J., Timpson, Nicholas J., Cheng, Ching-Yu, Wong, Tien-Yin, Khor, Chiea Chuen, Li, Hengtong, Sabanayagam, Charumathi, Peters, Annette, Gieger, Christian, Hattersley, Andrew T., Pedersen, Nancy L., Magnusson, Patrik K. E., Boomsma, Dorret I., Willemsen, Allegonda H. M., Cupples, LAdrienne, van Meurs, Joyce B. J., Ghanbari, Mohsen, Gordon-Larsen, Penny, Huang, Wei, Kim, Young Jin, Tabara, Yasuharu, Wareham, Nicholas J., Langenberg, Claudia, Zeggini, Eleftheria, Kuusisto, Johanna, Laakso, Markku, Ingelsson, Erik, Abecasis, Goncalo, Chambers, John C., Kooner, Jaspal S., de Vries, Paul S., Morrison, Alanna C., Hazelhurst, Scott, Ramsay, Michèle, North, Kari E., Daviglus, Martha, Kraft, Peter, Martin, Nicholas G., Whitfield, John B., Abbas, Shahid, Saleheen, Danish, Walters, Robin G., Holmes, Michael V., Black, Corri, Smith, Blair H., Baras, Aris, Justice, Anne E., Buring, Julie E., Ridker, Paul M., Chasman, Daniel I., Kooperberg, Charles, Tamiya, Gen, Yamamoto, Masayuki, van Heel, David A., Trembath, Richard C., Wei, Wei-Qi, Jarvik, Gail P., Namjou, Bahram, Hayes, M. Geoffrey, Ritchie, Marylyn D., Jousilahti, Pekka, Salomaa, Veikko, Hveem, Kristian, Åsvold, Bjørn Olav, Kubo, Michiaki, Kamatani, Yoichiro, Okada, Yukinori, Murakami, Yoshinori, Kim, Bong-Jo, Thorsteinsdottir, Unnur, Stefansson, Kari, Zhang, Jifeng, Chen, YEugene, Ho, Yuk-Lam, Lynch, Julie A., Rader, Daniel J., Tsao, Philip S., Chang, Kyong-Mi, Cho, Kelly, O’Donnell, Christopher J., Gaziano, John M., Wilson, Peter W. F., Frayling, Timothy M., Hirschhorn, Joel N., Kathiresan, Sekar, Mohlke, Karen L., Sun, Yan V., Morris, Andrew P., Boehnke, Michael, Brown, Christopher D., Natarajan, Pradeep, Deloukas, Panos, Willer, Cristen J., Assimes, Themistocles L., and Peloso, Gina M.
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- 2022
- Full Text
- View/download PDF
14. The power of genetic diversity in genome-wide association studies of lipids
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Graham, Sarah E., Clarke, Shoa L., Wu, Kuan-Han H., Kanoni, Stavroula, Zajac, Greg J. M., Ramdas, Shweta, Surakka, Ida, Ntalla, Ioanna, Vedantam, Sailaja, Winkler, Thomas W., Locke, Adam E., Marouli, Eirini, Hwang, Mi Yeong, Han, Sohee, Narita, Akira, Choudhury, Ananyo, Bentley, Amy R., Ekoru, Kenneth, Verma, Anurag, Trivedi, Bhavi, Martin, Hilary C., Hunt, Karen A., Hui, Qin, Klarin, Derek, Zhu, Xiang, Thorleifsson, Gudmar, Helgadottir, Anna, Gudbjartsson, Daniel F., Holm, Hilma, Olafsson, Isleifur, Akiyama, Masato, Sakaue, Saori, Terao, Chikashi, Kanai, Masahiro, Zhou, Wei, Brumpton, Ben M., Rasheed, Humaira, Ruotsalainen, Sanni E., Havulinna, Aki S., Veturi, Yogasudha, Feng, QiPing, Rosenthal, Elisabeth A., Lingren, Todd, Pacheco, Jennifer Allen, Pendergrass, Sarah A., Haessler, Jeffrey, Giulianini, Franco, Bradford, Yuki, Miller, Jason E., Campbell, Archie, Lin, Kuang, Millwood, Iona Y., Hindy, George, Rasheed, Asif, Faul, Jessica D., Zhao, Wei, Weir, David R., Turman, Constance, Huang, Hongyan, Graff, Mariaelisa, Mahajan, Anubha, Brown, Michael R., Zhang, Weihua, Yu, Ketian, Schmidt, Ellen M., Pandit, Anita, Gustafsson, Stefan, Yin, Xianyong, Luan, Jian’an, Zhao, Jing-Hua, Matsuda, Fumihiko, Jang, Hye-Mi, Yoon, Kyungheon, Medina-Gomez, Carolina, Pitsillides, Achilleas, Hottenga, Jouke Jan, Willemsen, Gonneke, Wood, Andrew R., Ji, Yingji, Gao, Zishan, Haworth, Simon, Mitchell, Ruth E., Chai, Jin Fang, Aadahl, Mette, Yao, Jie, Manichaikul, Ani, Warren, Helen R., Ramirez, Julia, Bork-Jensen, Jette, Kårhus, Line L., Goel, Anuj, Sabater-Lleal, Maria, Noordam, Raymond, Sidore, Carlo, Fiorillo, Edoardo, McDaid, Aaron F., Marques-Vidal, Pedro, Wielscher, Matthias, Trompet, Stella, Sattar, Naveed, Møllehave, Line T., Thuesen, Betina H., Munz, Matthias, Zeng, Lingyao, Huang, Jianfeng, Yang, Bin, Poveda, Alaitz, Kurbasic, Azra, Lamina, Claudia, Forer, Lukas, Scholz, Markus, Galesloot, Tessel E., Bradfield, Jonathan P., Daw, E. Warwick, Zmuda, Joseph M., Mitchell, Jonathan S., Fuchsberger, Christian, Christensen, Henry, Brody, Jennifer A., Feitosa, Mary F., Wojczynski, Mary K., Preuss, Michael, Mangino, Massimo, Christofidou, Paraskevi, Verweij, Niek, Benjamins, Jan W., Engmann, Jorgen, Kember, Rachel L., Slieker, Roderick C., Lo, Ken Sin, Zilhao, Nuno R., Le, Phuong, Kleber, Marcus E., Delgado, Graciela E., Huo, Shaofeng, Ikeda, Daisuke D., Iha, Hiroyuki, Yang, Jian, Liu, Jun, Leonard, Hampton L., Marten, Jonathan, Schmidt, Börge, Arendt, Marina, Smyth, Laura J., Cañadas-Garre, Marisa, Wang, Chaolong, Nakatochi, Masahiro, Wong, Andrew, Hutri-Kähönen, Nina, Sim, Xueling, Xia, Rui, Huerta-Chagoya, Alicia, Fernandez-Lopez, Juan Carlos, Lyssenko, Valeriya, Ahmed, Meraj, Jackson, Anne U., Yousri, Noha A., Irvin, Marguerite R., Oldmeadow, Christopher, Kim, Han-Na, Ryu, Seungho, Timmers, Paul R. H. J., Arbeeva, Liubov, Dorajoo, Rajkumar, Lange, Leslie A., Chai, Xiaoran, Prasad, Gauri, Lorés-Motta, Laura, Pauper, Marc, Long, Jirong, Li, Xiaohui, Theusch, Elizabeth, Takeuchi, Fumihiko, Spracklen, Cassandra N., Loukola, Anu, Bollepalli, Sailalitha, Warner, Sophie C., Wang, Ya Xing, Wei, Wen B., Nutile, Teresa, Ruggiero, Daniela, Sung, Yun Ju, Hung, Yi-Jen, Chen, Shufeng, Liu, Fangchao, Yang, Jingyun, Kentistou, Katherine A., Gorski, Mathias, Brumat, Marco, Meidtner, Karina, Bielak, Lawrence F., Smith, Jennifer A., Hebbar, Prashantha, Farmaki, Aliki-Eleni, Hofer, Edith, Lin, Maoxuan, Xue, Chao, Zhang, Jifeng, Concas, Maria Pina, Vaccargiu, Simona, van der Most, Peter J., Pitkänen, Niina, Cade, Brian E., Lee, Jiwon, van der Laan, Sander W., Chitrala, Kumaraswamy Naidu, Weiss, Stefan, Zimmermann, Martina E., Lee, Jong Young, Choi, Hyeok Sun, Nethander, Maria, Freitag-Wolf, Sandra, Southam, Lorraine, Rayner, Nigel W., Wang, Carol A., Lin, Shih-Yi, Wang, Jun-Sing, Couture, Christian, Lyytikäinen, Leo-Pekka, Nikus, Kjell, Cuellar-Partida, Gabriel, Vestergaard, Henrik, Hildalgo, Bertha, Giannakopoulou, Olga, Cai, Qiuyin, Obura, Morgan O., van Setten, Jessica, Li, Xiaoyin, Schwander, Karen, Terzikhan, Natalie, Shin, Jae Hun, Jackson, Rebecca D., Reiner, Alexander P., Martin, Lisa Warsinger, Chen, Zhengming, Li, Liming, Highland, Heather M., Young, Kristin L., Kawaguchi, Takahisa, Thiery, Joachim, Bis, Joshua C., Nadkarni, Girish N., Launer, Lenore J., Li, Huaixing, Nalls, Mike A., Raitakari, Olli T., Ichihara, Sahoko, Wild, Sarah H., Nelson, Christopher P., Campbell, Harry, Jäger, Susanne, Nabika, Toru, Al-Mulla, Fahd, Niinikoski, Harri, Braund, Peter S., Kolcic, Ivana, Kovacs, Peter, Giardoglou, Tota, Katsuya, Tomohiro, Bhatti, Konain Fatima, de Kleijn, Dominique, de Borst, Gert J., Kim, Eung Kweon, Adams, Hieab H. H., Ikram, M. Arfan, Zhu, Xiaofeng, Asselbergs, Folkert W., Kraaijeveld, Adriaan O., Beulens, Joline W. J., Shu, Xiao-Ou, Rallidis, Loukianos S., Pedersen, Oluf, Hansen, Torben, Mitchell, Paul, Hewitt, Alex W., Kähönen, Mika, Pérusse, Louis, Bouchard, Claude, Tönjes, Anke, Chen, Yii-Der Ida, Pennell, Craig E., Mori, Trevor A., Lieb, Wolfgang, Franke, Andre, Ohlsson, Claes, Mellström, Dan, Cho, Yoon Shin, Lee, Hyejin, Yuan, Jian-Min, Koh, Woon-Puay, Rhee, Sang Youl, Woo, Jeong-Taek, Heid, Iris M., Stark, Klaus J., Völzke, Henry, Homuth, Georg, Evans, Michele K., Zonderman, Alan B., Polasek, Ozren, Pasterkamp, Gerard, Hoefer, Imo E., Redline, Susan, Pahkala, Katja, Oldehinkel, Albertine J., Snieder, Harold, Biino, Ginevra, Schmidt, Reinhold, Schmidt, Helena, Chen, Y. Eugene, Bandinelli, Stefania, Dedoussis, George, Thanaraj, Thangavel Alphonse, Kardia, Sharon L. R., Kato, Norihiro, Schulze, Matthias B., Girotto, Giorgia, Jung, Bettina, Böger, Carsten A., Joshi, Peter K., Bennett, David A., De Jager, Philip L., Lu, Xiangfeng, Mamakou, Vasiliki, Brown, Morris, Caulfield, Mark J., Munroe, Patricia B., Guo, Xiuqing, Ciullo, Marina, Jonas, Jost B., Samani, Nilesh J., Kaprio, Jaakko, Pajukanta, Päivi, Adair, Linda S., Bechayda, Sonny Augustin, de Silva, H. Janaka, Wickremasinghe, Ananda R., Krauss, Ronald M., Wu, Jer-Yuarn, Zheng, Wei, den Hollander, Anneke I., Bharadwaj, Dwaipayan, Correa, Adolfo, Wilson, James G., Lind, Lars, Heng, Chew-Kiat, Nelson, Amanda E., Golightly, Yvonne M., Wilson, James F., Penninx, Brenda, Kim, Hyung-Lae, Attia, John, Scott, Rodney J., Rao, D. C., Arnett, Donna K., Hunt, Steven C., Walker, Mark, Koistinen, Heikki A., Chandak, Giriraj R., Yajnik, Chittaranjan S., Mercader, Josep M., Tusié-Luna, Teresa, Aguilar-Salinas, Carlos A., Villalpando, Clicerio Gonzalez, Orozco, Lorena, Fornage, Myriam, Tai, E. Shyong, van Dam, Rob M., Lehtimäki, Terho, Chaturvedi, Nish, Yokota, Mitsuhiro, Liu, Jianjun, Reilly, Dermot F., McKnight, Amy Jayne, Kee, Frank, Jöckel, Karl-Heinz, McCarthy, Mark I., Palmer, Colin N. A., Vitart, Veronique, Hayward, Caroline, Simonsick, Eleanor, van Duijn, Cornelia M., Lu, Fan, Qu, Jia, Hishigaki, Haretsugu, Lin, Xu, März, Winfried, Parra, Esteban J., Cruz, Miguel, Gudnason, Vilmundur, Tardif, Jean-Claude, Lettre, Guillaume, ’t Hart, Leen M., Elders, Petra J. M., Damrauer, Scott M., Kumari, Meena, Kivimaki, Mika, van der Harst, Pim, Spector, Tim D., Loos, Ruth J. F., Province, Michael A., Psaty, Bruce M., Brandslund, Ivan, Pramstaller, Peter P., Christensen, Kaare, Ripatti, Samuli, Widén, Elisabeth, Hakonarson, Hakon, Grant, Struan F. A., Kiemeney, Lambertus A. L. M., de Graaf, Jacqueline, Loeffler, Markus, Kronenberg, Florian, Gu, Dongfeng, Erdmann, Jeanette, Schunkert, Heribert, Franks, Paul W., Linneberg, Allan, Jukema, J. Wouter, Khera, Amit V., Männikkö, Minna, Jarvelin, Marjo-Riitta, Kutalik, Zoltan, Cucca, Francesco, Mook-Kanamori, Dennis O., van Dijk, Ko Willems, Watkins, Hugh, Strachan, David P., Grarup, Niels, Sever, Peter, Poulter, Neil, Rotter, Jerome I., Dantoft, Thomas M., Karpe, Fredrik, Neville, Matt J., Timpson, Nicholas J., Cheng, Ching-Yu, Wong, Tien-Yin, Khor, Chiea Chuen, Sabanayagam, Charumathi, Peters, Annette, Gieger, Christian, Hattersley, Andrew T., Pedersen, Nancy L., Magnusson, Patrik K. E., Boomsma, Dorret I., de Geus, Eco J. C., Cupples, L. Adrienne, van Meurs, Joyce B. J., Ghanbari, Mohsen, Gordon-Larsen, Penny, Huang, Wei, Kim, Young Jin, Tabara, Yasuharu, Wareham, Nicholas J., Langenberg, Claudia, Zeggini, Eleftheria, Kuusisto, Johanna, Laakso, Markku, Ingelsson, Erik, Abecasis, Goncalo, Chambers, John C., Kooner, Jaspal S., de Vries, Paul S., Morrison, Alanna C., North, Kari E., Daviglus, Martha, Kraft, Peter, Martin, Nicholas G., Whitfield, John B., Abbas, Shahid, Saleheen, Danish, Walters, Robin G., Holmes, Michael V., Black, Corri, Smith, Blair H., Justice, Anne E., Baras, Aris, Buring, Julie E., Ridker, Paul M., Chasman, Daniel I., Kooperberg, Charles, Wei, Wei-Qi, Jarvik, Gail P., Namjou, Bahram, Hayes, M. Geoffrey, Ritchie, Marylyn D., Jousilahti, Pekka, Salomaa, Veikko, Hveem, Kristian, Åsvold, Bjørn Olav, Kubo, Michiaki, Kamatani, Yoichiro, Okada, Yukinori, Murakami, Yoshinori, Thorsteinsdottir, Unnur, Stefansson, Kari, Ho, Yuk-Lam, Lynch, Julie A., Rader, Daniel J., Tsao, Philip S., Chang, Kyong-Mi, Cho, Kelly, O’Donnell, Christopher J., Gaziano, John M., Wilson, Peter, Rotimi, Charles N., Hazelhurst, Scott, Ramsay, Michèle, Trembath, Richard C., van Heel, David A., Tamiya, Gen, Yamamoto, Masayuki, Kim, Bong-Jo, Mohlke, Karen L., Frayling, Timothy M., Hirschhorn, Joel N., Kathiresan, Sekar, Boehnke, Michael, Natarajan, Pradeep, Peloso, Gina M., Brown, Christopher D., Morris, Andrew P., Assimes, Themistocles L., Deloukas, Panos, Sun, Yan V., and Willer, Cristen J.
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- 2021
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15. Genetic correlations among psychiatric and immune‐related phenotypes based on genome‐wide association data
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Tylee, Daniel S, Sun, Jiayin, Hess, Jonathan L, Tahir, Muhammad A, Sharma, Esha, Malik, Rainer, Worrall, Bradford B, Levine, Andrew J, Martinson, Jeremy J, Nejentsev, Sergey, Speed, Doug, Fischer, Annegret, Mick, Eric, Walker, Brian R, Crawford, Andrew, Grant, Struan FA, Polychronakos, Constantin, Bradfield, Jonathan P, Sleiman, Patrick MA, Hakonarson, Hakon, Ellinghaus, Eva, Elder, James T, Tsoi, Lam C, Trembath, Richard C, Barker, Jonathan N, Franke, Andre, Dehghan, Abbas, Team, The 23 and Me Research, Consortium, The Inflammation Working Group of the CHARGE, Consortium, The METASTROKE Consortium of the International Stroke Genetics, Registry, The Netherlands Twin, Group, The neuroCHARGE Working, Consortium, The Obsessive Compulsive and Tourette Syndrome Working Group of the Psychiatric Genomics, Faraone, Stephen V, and Glatt, Stephen J
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Pharmacology and Pharmaceutical Sciences ,Biological Sciences ,Biomedical and Clinical Sciences ,Genetics ,Serious Mental Illness ,Human Genome ,Genetic Testing ,Brain Disorders ,Schizophrenia ,Digestive Diseases ,Prevention ,Mental Health ,Clinical Research ,Autoimmune Disease ,2.1 Biological and endogenous factors ,Aetiology ,Mental health ,Autoimmune Diseases ,Comorbidity ,Databases ,Factual ,Female ,Genetic Predisposition to Disease ,Genome-Wide Association Study ,Humans ,Linkage Disequilibrium ,Male ,Mental Disorders ,Multifactorial Inheritance ,Polymorphism ,Single Nucleotide ,White People ,allergy ,anorexia nervosa ,attention deficit-hyperactivity disorder ,autoimmune disorder ,bipolar disorder ,celiac disease ,childhood ear infection ,C-reactive protein ,Crohn's disease ,genetic correlation ,genome-wide association ,hypothyroidism ,major depression ,neuroticism ,obsessive schizophrenia ,primary biliary cirrhosis ,rheumatoid arthritis ,smoking ,systemic lupus erythematosus ,Tourette syndrome ,tuberculosis susceptibility ,type 1 diabetes ,ulcerative colitis ,and Me Research Team ,Inflammation Working Group of the CHARGE Consortium ,METASTROKE Consortium of the International Stroke Genetics Consortium ,Netherlands Twin Registry ,neuroCHARGE Working Group ,Obsessive Compulsive and Tourette Syndrome Working Group of the Psychiatric Genomics Consortium ,Clinical Sciences ,Neurosciences ,Clinical sciences - Abstract
Individuals with psychiatric disorders have elevated rates of autoimmune comorbidity and altered immune signaling. It is unclear whether these altered immunological states have a shared genetic basis with those psychiatric disorders. The present study sought to use existing summary-level data from previous genome-wide association studies to determine if commonly varying single nucleotide polymorphisms are shared between psychiatric and immune-related phenotypes. We estimated heritability and examined pair-wise genetic correlations using the linkage disequilibrium score regression (LDSC) and heritability estimation from summary statistics methods. Using LDSC, we observed significant genetic correlations between immune-related disorders and several psychiatric disorders, including anorexia nervosa, attention deficit-hyperactivity disorder, bipolar disorder, major depression, obsessive compulsive disorder, schizophrenia, smoking behavior, and Tourette syndrome. Loci significantly mediating genetic correlations were identified for schizophrenia when analytically paired with Crohn's disease, primary biliary cirrhosis, systemic lupus erythematosus, and ulcerative colitis. We report significantly correlated loci and highlight those containing genome-wide associations and candidate genes for respective disorders. We also used the LDSC method to characterize genetic correlations among the immune-related phenotypes. We discuss our findings in the context of relevant genetic and epidemiological literature, as well as the limitations and caveats of the study.
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- 2018
16. Identification of rare sequence variation underlying heritable pulmonary arterial hypertension.
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Gräf, Stefan, Haimel, Matthias, Bleda, Marta, Hadinnapola, Charaka, Southgate, Laura, Li, Wei, Hodgson, Joshua, Liu, Bin, Salmon, Richard M, Southwood, Mark, Machado, Rajiv D, Martin, Jennifer M, Treacy, Carmen M, Yates, Katherine, Daugherty, Louise C, Shamardina, Olga, Whitehorn, Deborah, Holden, Simon, Aldred, Micheala, Bogaard, Harm J, Church, Colin, Coghlan, Gerry, Condliffe, Robin, Corris, Paul A, Danesino, Cesare, Eyries, Mélanie, Gall, Henning, Ghio, Stefano, Ghofrani, Hossein-Ardeschir, Gibbs, J Simon R, Girerd, Barbara, Houweling, Arjan C, Howard, Luke, Humbert, Marc, Kiely, David G, Kovacs, Gabor, MacKenzie Ross, Robert V, Moledina, Shahin, Montani, David, Newnham, Michael, Olschewski, Andrea, Olschewski, Horst, Peacock, Andrew J, Pepke-Zaba, Joanna, Prokopenko, Inga, Rhodes, Christopher J, Scelsi, Laura, Seeger, Werner, Soubrier, Florent, Stein, Dan F, Suntharalingam, Jay, Swietlik, Emilia M, Toshner, Mark R, van Heel, David A, Vonk Noordegraaf, Anton, Waisfisz, Quinten, Wharton, John, Wort, Stephen J, Ouwehand, Willem H, Soranzo, Nicole, Lawrie, Allan, Upton, Paul D, Wilkins, Martin R, Trembath, Richard C, and Morrell, Nicholas W
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Humans ,Genetic Predisposition to Disease ,Transforming Growth Factor beta ,Membrane Transport Proteins ,Prognosis ,Case-Control Studies ,Signal Transduction ,Gene Expression Regulation ,Base Sequence ,Mutation ,Models ,Molecular ,Adult ,Female ,Male ,Aquaporin 1 ,Bone Morphogenetic Protein Receptors ,Type II ,Adenosine Triphosphatases ,Growth Differentiation Factors ,SOXF Transcription Factors ,HEK293 Cells ,Familial Primary Pulmonary Hypertension ,Whole Genome Sequencing ,Bone Morphogenetic Protein Receptors ,Type II ,Models ,Molecular - Abstract
Pulmonary arterial hypertension (PAH) is a rare disorder with a poor prognosis. Deleterious variation within components of the transforming growth factor-β pathway, particularly the bone morphogenetic protein type 2 receptor (BMPR2), underlies most heritable forms of PAH. To identify the missing heritability we perform whole-genome sequencing in 1038 PAH index cases and 6385 PAH-negative control subjects. Case-control analyses reveal significant overrepresentation of rare variants in ATP13A3, AQP1 and SOX17, and provide independent validation of a critical role for GDF2 in PAH. We demonstrate familial segregation of mutations in SOX17 and AQP1 with PAH. Mutations in GDF2, encoding a BMPR2 ligand, lead to reduced secretion from transfected cells. In addition, we identify pathogenic mutations in the majority of previously reported PAH genes, and provide evidence for further putative genes. Taken together these findings contribute new insights into the molecular basis of PAH and indicate unexplored pathways for therapeutic intervention.
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- 2018
17. Allele-specific control of rodent and human lncRNA KMT2E-AS1 promotes hypoxic endothelial pathology in pulmonary hypertension
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Tai, Yi-Yin, primary, Yu, Qiujun, additional, Tang, Ying, additional, Sun, Wei, additional, Kelly, Neil J., additional, Okawa, Satoshi, additional, Zhao, Jingsi, additional, Schwantes-An, Tae-Hwi, additional, Lacoux, Caroline, additional, Torrino, Stephanie, additional, Al Aaraj, Yassmin, additional, El Khoury, Wadih, additional, Negi, Vinny, additional, Liu, Mingjun, additional, Corey, Catherine G., additional, Belmonte, Frances, additional, Vargas, Sara O., additional, Schwartz, Brian, additional, Bhat, Bal, additional, Chau, B. Nelson, additional, Karnes, Jason H., additional, Satoh, Taijyu, additional, Barndt, Robert J., additional, Wu, Haodi, additional, Parikh, Victoria N., additional, Wang, Jianrong, additional, Zhang, Yingze, additional, McNamara, Dennis, additional, Li, Gang, additional, Speyer, Gil, additional, Wang, Bing, additional, Shiva, Sruti, additional, Kaufman, Brett, additional, Kim, Seungchan, additional, Gomez, Delphine, additional, Mari, Bernard, additional, Cho, Michael H., additional, Boueiz, Adel, additional, Pauciulo, Michael W., additional, Southgate, Laura, additional, Trembath, Richard C., additional, Sitbon, Olivier, additional, Humbert, Marc, additional, Graf, Stefan, additional, Morrell, Nicholas W., additional, Rhodes, Christopher J., additional, Wilkins, Martin R., additional, Nouraie, Mehdi, additional, Nichols, William C., additional, Desai, Ankit A., additional, Bertero, Thomas, additional, and Chan, Stephen Y., additional
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- 2024
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18. Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci
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Ellinghaus, David, Jostins, Luke, Spain, Sarah L, Cortes, Adrian, Bethune, Jörn, Han, Buhm, Park, Yu Rang, Raychaudhuri, Soumya, Pouget, Jennie G, Hübenthal, Matthias, Folseraas, Trine, Wang, Yunpeng, Esko, Tonu, Metspalu, Andres, Westra, Harm-Jan, Franke, Lude, Pers, Tune H, Weersma, Rinse K, Collij, Valerie, D'Amato, Mauro, Halfvarson, Jonas, Jensen, Anders Boeck, Lieb, Wolfgang, Degenhardt, Franziska, Forstner, Andreas J, Hofmann, Andrea, Schreiber, Stefan, Mrowietz, Ulrich, Juran, Brian D, Lazaridis, Konstantinos N, Brunak, Søren, Dale, Anders M, Trembath, Richard C, Weidinger, Stephan, Weichenthal, Michael, Ellinghaus, Eva, Elder, James T, Barker, Jonathan NWN, Andreassen, Ole A, McGovern, Dermot P, Karlsen, Tom H, Barrett, Jeffrey C, Parkes, Miles, Brown, Matthew A, and Franke, Andre
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Biological Sciences ,Genetics ,Prevention ,2.1 Biological and endogenous factors ,Aetiology ,Inflammatory and immune system ,Bayes Theorem ,Cholangitis ,Sclerosing ,Chronic Disease ,Colitis ,Ulcerative ,Comorbidity ,Crohn Disease ,Genetic Heterogeneity ,Genetic Pleiotropy ,Genetic Variation ,Genome-Wide Association Study ,Genotype ,Humans ,Inflammation ,Psoriasis ,Quantitative Trait Loci ,Spondylitis ,Ankylosing ,International IBD Genetics Consortium ,International Genetics of Ankylosing Spondylitis Consortium ,International PSC Study Group ,Genetic Analysis of Psoriasis Consortium ,Psoriasis Association Genetics Extension ,Medical and Health Sciences ,Developmental Biology ,Agricultural biotechnology ,Bioinformatics and computational biology - Abstract
We simultaneously investigated the genetic landscape of ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis and ulcerative colitis to investigate pleiotropy and the relationship between these clinically related diseases. Using high-density genotype data from more than 86,000 individuals of European ancestry, we identified 244 independent multidisease signals, including 27 new genome-wide significant susceptibility loci and 3 unreported shared risk loci. Complex pleiotropy was supported when contrasting multidisease signals with expression data sets from human, rat and mouse together with epigenetic and expressed enhancer profiles. The comorbidities among the five immune diseases were best explained by biological pleiotropy rather than heterogeneity (a subgroup of cases genetically identical to those with another disease, possibly owing to diagnostic misclassification, molecular subtypes or excessive comorbidity). In particular, the strong comorbidity between primary sclerosing cholangitis and inflammatory bowel disease is likely the result of a unique disease, which is genetically distinct from classical inflammatory bowel disease phenotypes.
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- 2016
19. Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis
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Rhodes, Christopher J, Batai, Ken, Bleda, Marta, Haimel, Matthias, Southgate, Laura, Germain, Marine, Pauciulo, Michael W, Hadinnapola, Charaka, Aman, Jurjan, Girerd, Barbara, Arora, Amit, Knight, Jo, Hanscombe, Ken B, Karnes, Jason H, Kaakinen, Marika, Gall, Henning, Ulrich, Anna, Harbaum, Lars, Cebola, Inês, Ferrer, Jorge, Lutz, Katie, Swietlik, Emilia M, Ahmad, Ferhaan, Amouyel, Philippe, Archer, Stephen L, Argula, Rahul, Austin, Eric D, Badesch, David, Bakshi, Sahil, Barnett, Christopher, Benza, Raymond, Bhatt, Nitin, Bogaard, Harm J, Burger, Charles D, Chakinala, Murali, Church, Colin, Coghlan, John G, Condliffe, Robin, Corris, Paul A, Danesino, Cesare, Debette, Stéphanie, Elliott, C Gregory, Elwing, Jean, Eyries, Melanie, Fortin, Terry, Franke, Andre, Frantz, Robert P, Frost, Adaani, Garcia, Joe G N, Ghio, Stefano, Ghofrani, Hossein-Ardeschir, Gibbs, J Simon R, Harley, John, He, Hua, Hill, Nicholas S, Hirsch, Russel, Houweling, Arjan C, Howard, Luke S, Ivy, Dunbar, Kiely, David G, Klinger, James, Kovacs, Gabor, Lahm, Tim, Laudes, Matthias, Machado, Rajiv D, MacKenzie Ross, Robert V, Marsolo, Keith, Martin, Lisa J, Moledina, Shahin, Montani, David, Nathan, Steven D, Newnham, Michael, Olschewski, Andrea, Olschewski, Horst, Oudiz, Ronald J, Ouwehand, Willem H, Peacock, Andrew J, Pepke-Zaba, Joanna, Rehman, Zia, Robbins, Ivan, Roden, Dan M, Rosenzweig, Erika B, Saydain, Ghulam, Scelsi, Laura, Schilz, Robert, Seeger, Werner, Shaffer, Christian M, Simms, Robert W, Simon, Marc, Sitbon, Olivier, Suntharalingam, Jay, Tang, Haiyang, Tchourbanov, Alexander Y, Thenappan, Thenappan, Torres, Fernando, Toshner, Mark R, Treacy, Carmen M, Vonk Noordegraaf, Anton, Waisfisz, Quinten, Walsworth, Anna K, Walter, Robert E, Wharton, John, White, R James, Wilt, Jeffrey, Wort, Stephen J, Yung, Delphine, Lawrie, Allan, Humbert, Marc, Soubrier, Florent, Trégouët, David-Alexandre, Prokopenko, Inga, Kittles, Richard, Gräf, Stefan, Nichols, William C, Trembath, Richard C, Desai, Ankit A, Morrell, Nicholas W, and Wilkins, Martin R
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- 2019
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20. Integrating polygenic risk scores in the prediction of type 2 diabetes risk and subtypes in British Pakistanis and Bangladeshis: A population-based cohort study
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Hodgson, Sam, Huang, Qin Qin, Sallah, Neneh, Griffiths, Chris J., Newman, William G., Trembath, Richard C., Wright, John, Lumbers, R. Thomas, Kuchenbaecker, Karoline, van Heel, David A., Mathur, Rohini, Martin, Hilary C., and Finer, Sarah
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Bangladeshis -- Health aspects -- Genetic aspects ,Pakistanis -- Health aspects -- Genetic aspects ,Type 2 diabetes -- Risk factors -- Genetic aspects ,Biological sciences - Abstract
Background Type 2 diabetes (T2D) is highly prevalent in British South Asians, yet they are underrepresented in research. Genes & Health (G&H) is a large, population study of British Pakistanis and Bangladeshis (BPB) comprising genomic and routine health data. We assessed the extent to which genetic risk for T2D is shared between BPB and European populations (EUR). We then investigated whether the integration of a polygenic risk score (PRS) for T2D with an existing risk tool (QDiabetes) could improve prediction of incident disease and the characterisation of disease subtypes. Methods and findings In this observational cohort study, we assessed whether common genetic loci associated with T2D in EUR individuals were replicated in 22,490 BPB individuals in G&H. We replicated fewer loci in G&H (n = 76/338, 22%) than would be expected given power if all EUR-ascertained loci were transferable (n = 101, 30%; p = 0.001). Of the 27 transferable loci that were powered to interrogate this, only 9 showed evidence of shared causal variants. We constructed a T2D PRS and combined it with a clinical risk instrument (QDiabetes) in a novel, integrated risk tool (IRT) to assess risk of incident diabetes. To assess model performance, we compared categorical net reclassification index (NRI) versus QDiabetes alone. In 13,648 patients free from T2D followed up for 10 years, NRI was 3.2% for IRT versus QDiabetes (95% confidence interval (CI): 2.0% to 4.4%). IRT performed best in reclassification of individuals aged less than 40 years deemed low risk by QDiabetes alone (NRI 5.6%, 95% CI 3.6% to 7.6%), who tended to be free from comorbidities and slim. After adjustment for QDiabetes score, PRS was independently associated with progression to T2D after gestational diabetes (hazard ratio (HR) per SD of PRS 1.23, 95% CI 1.05 to 1.42, p = 0.028). Using cluster analysis of clinical features at diabetes diagnosis, we replicated previously reported disease subgroups, including Mild Age-Related, Mild Obesity-related, and Insulin-Resistant Diabetes, and showed that PRS distribution differs between subgroups (p = 0.002). Integrating PRS in this cluster analysis revealed a Probable Severe Insulin Deficient Diabetes (pSIDD) subgroup, despite the absence of clinical measures of insulin secretion or resistance. We also observed differences in rates of progression to micro- and macrovascular complications between subgroups after adjustment for confounders. Study limitations include the absence of an external replication cohort and the potential biases arising from missing or incorrect routine health data. Conclusions Our analysis of the transferability of T2D loci between EUR and BPB indicates the need for larger, multiancestry studies to better characterise the genetic contribution to disease and its varied aetiology. We show that a T2D PRS optimised for this high-risk BPB population has potential clinical application in BPB, improving the identification of T2D risk (especially in the young) on top of an established clinical risk algorithm and aiding identification of subgroups at diagnosis, which may help future efforts to stratify care and treatment of the disease., Author(s): Sam Hodgson 1, Qin Qin Huang 2, Neneh Sallah 3,4, Genes & Health Research Team 5,6, Chris J. Griffiths 5, William G. Newman 7,8, Richard C. Trembath 9, John [...]
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- 2022
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21. Genome-wide association analysis identifies 13 new risk loci for schizophrenia
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Donnelly, Peter, Barroso, Ines, Blackwell, Jenefer M, Bramon, Elvira, Brown, Matthew A, Casas, Juan P, Corvin, Aiden P, Deloukas, Panos, Duncanson, Audrey, Jankowski, Janusz, Markus, Hugh S, Mathew, Christopher G, Palmer, Colin NA, Plomin, Robert, Rautanen, Anna, Sawcer, Stephen J, Trembath, Richard C, Viswanathan, Ananth C, Wood, Nicholas W, Spencer, Chris CA, Band, Gavin, Bellenguez, Céline, Freeman, Colin, Hellenthal, Garrett, Giannoulatou, Eleni, Pirinen, Matti, Pearson, Richard D, Strange, Amy, Su, Zhan, Vukcevic, Damjan, Langford, Cordelia, Hunt, Sarah E, Edkins, Sarah, Gwilliam, Rhian, Blackburn, Hannah, Bumpstead, Suzannah J, Dronov, Serge, Gillman, Matthew, Gray, Emma, Hammond, Naomi, Jayakumar, Alagurevathi, McCann, Owen T, Liddle, Jennifer, Potter, Simon C, Ravindrarajah, Radhi, Ricketts, Michelle, Tashakkori-Ghanbaria, Avazeh, Waller, Matthew J, Weston, Paul, Widaa, Sara, Whittaker, Pamela, and McCarthy, Mark I
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Mental health ,Case-Control Studies ,Female ,Genetic Predisposition to Disease ,Genome-Wide Association Study ,Humans ,Male ,Polymorphism ,Single Nucleotide ,Schizophrenia ,Sweden ,Multicenter Genetic Studies of Schizophrenia Consortium ,Psychosis Endophenotypes International Consortium ,Wellcome Trust Case Control Consortium 2 ,Biological Sciences ,Medical and Health Sciences ,Developmental Biology - Abstract
Schizophrenia is an idiopathic mental disorder with a heritable component and a substantial public health impact. We conducted a multi-stage genome-wide association study (GWAS) for schizophrenia beginning with a Swedish national sample (5,001 cases and 6,243 controls) followed by meta-analysis with previous schizophrenia GWAS (8,832 cases and 12,067 controls) and finally by replication of SNPs in 168 genomic regions in independent samples (7,413 cases, 19,762 controls and 581 parent-offspring trios). We identified 22 loci associated at genome-wide significance; 13 of these are new, and 1 was previously implicated in bipolar disorder. Examination of candidate genes at these loci suggests the involvement of neuronal calcium signaling. We estimate that 8,300 independent, mostly common SNPs (95% credible interval of 6,300-10,200 SNPs) contribute to risk for schizophrenia and that these collectively account for at least 32% of the variance in liability. Common genetic variation has an important role in the etiology of schizophrenia, and larger studies will allow more detailed understanding of this disorder.
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- 2013
22. Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity
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Tsoi, Lam C, Spain, Sarah L, Knight, Jo, Ellinghaus, Eva, Stuart, Philip E, Capon, Francesca, Ding, Jun, Li, Yanming, Tejasvi, Trilokraj, Gudjonsson, Johann E, Kang, Hyun M, Allen, Michael H, McManus, Ross, Novelli, Giuseppe, Samuelsson, Lena, Schalkwijk, Joost, Ståhle, Mona, Burden, A David, Smith, Catherine H, Cork, Michael J, Estivill, Xavier, Bowcock, Anne M, Krueger, Gerald G, Weger, Wolfgang, Worthington, Jane, Tazi-Ahnini, Rachid, Nestle, Frank O, Hayday, Adrian, Hoffmann, Per, Winkelmann, Juliane, Wijmenga, Cisca, Langford, Cordelia, Edkins, Sarah, Andrews, Robert, Blackburn, Hannah, Strange, Amy, Band, Gavin, Pearson, Richard D, Vukcevic, Damjan, Spencer, Chris CA, Deloukas, Panos, Mrowietz, Ulrich, Schreiber, Stefan, Weidinger, Stephan, Koks, Sulev, Kingo, Külli, Esko, Tonu, Metspalu, Andres, Lim, Henry W, Voorhees, John J, Weichenthal, Michael, Wichmann, H Erich, Chandran, Vinod, Rosen, Cheryl F, Rahman, Proton, Gladman, Dafna D, Griffiths, Christopher EM, Reis, Andre, Kere, Juha, Nair, Rajan P, Franke, Andre, Barker, Jonathan NWN, Abecasis, Goncalo R, Elder, James T, and Trembath, Richard C
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Genetics ,Autoimmune Disease ,Human Genome ,Psoriasis ,Aetiology ,2.1 Biological and endogenous factors ,Skin ,CARD Signaling Adaptor Proteins ,Core Binding Factor Alpha 3 Subunit ,DEAD Box Protein 58 ,DEAD-box RNA Helicases ,GTPase-Activating Proteins ,Genetic Loci ,Genetic Predisposition to Disease ,Genome-Wide Association Study ,Guanylate Cyclase ,Humans ,Immunity ,Innate ,Membrane Proteins ,Oligonucleotide Array Sequence Analysis ,Polymorphism ,Single Nucleotide ,Receptors ,Immunologic ,STAT3 Transcription Factor ,T-Lymphocytes ,White People ,Collaborative Association Study of Psoriasis ,Genetic Analysis of Psoriasis Consortium ,Psoriasis Association Genetics Extension ,Wellcome Trust Case Control Consortium 2 ,Biological Sciences ,Medical and Health Sciences ,Developmental Biology - Abstract
To gain further insight into the genetic architecture of psoriasis, we conducted a meta-analysis of 3 genome-wide association studies (GWAS) and 2 independent data sets genotyped on the Immunochip, including 10,588 cases and 22,806 controls. We identified 15 new susceptibility loci, increasing to 36 the number associated with psoriasis in European individuals. We also identified, using conditional analyses, five independent signals within previously known loci. The newly identified loci shared with other autoimmune diseases include candidate genes with roles in regulating T-cell function (such as RUNX3, TAGAP and STAT3). Notably, they included candidate genes whose products are involved in innate host defense, including interferon-mediated antiviral responses (DDX58), macrophage activation (ZC3H12C) and nuclear factor (NF)-κB signaling (CARD14 and CARM1). These results portend a better understanding of shared and distinctive genetic determinants of immune-mediated inflammatory disorders and emphasize the importance of the skin in innate and acquired host defense.
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- 2012
23. Initiation codon mutation in betaB1-crystallin (CRYBB1) associated with autosomal recessive nuclear pulverulent cataract.
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Meyer, Esther, Rahman, Fatimah, Owens, Jessica, Pasha, Shanaz, Morgan, Neil V, Trembath, Richard C, Stone, Edwin M, Moore, Anthony T, and Maher, Eamonn R
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Humans ,Cataract ,beta-Crystallin B Chain ,Codon ,Initiator ,Oligonucleotide Array Sequence Analysis ,DNA Mutational Analysis ,Family ,Microsatellite Repeats ,Genes ,Recessive ,Polymorphism ,Single Nucleotide ,Codon ,Initiator ,Genes ,Recessive ,Polymorphism ,Single Nucleotide ,Ophthalmology & Optometry ,Opthalmology and Optometry - Abstract
PurposeTo identify the molecular basis for autosomal recessively inherited congenital non-syndromic pulverulent cataracts in a consanguineous family with four affected children.MethodsAn autozygosity mapping strategy using high density SNP microarrays and microsatellite markers was employed to detect regions of homozygosity. Subsequently good candidate genes were screened for mutations by direct sequencing.ResultsThe SNP microarray data demonstrated a 24.96 Mb region of homozygosity at 22q11.21-22q13.2 which was confirmed by microsatellite marker analysis. The candidate target region contained the beta-crystallin gene cluster and direct sequencing in affected family members revealed a novel mutation in CRYBB1 (c.2T>A; p.Met1Lys).ConclusionsTo our knowledge this is the first case of an initiation codon mutation in a human crystallin gene, and only the second report of a CRYBB1 mutation associated with autosomal recessive congenital cataracts. In addition, although a number of genetic causes of autosomal dominant pulverulent cataracts have been identified (including CRYBB1) this is the first gene to have been implicated in autosomal recessive nuclear pulverulent cataract.
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- 2009
24. PIK3R3 is a candidate regulator of platelet count in people of Bangladeshi ancestry
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Burley, Kate, primary, Fitzgibbon, Lucy, additional, van Heel, David, additional, Vuckovic, Dragana, additional, Mumford, Andrew D., additional, Akhtar, Shaheen, additional, Anwar, Mohammad, additional, Arciero, Elena, additional, Asgar, Omar, additional, Ashraf, Samina, additional, Breen, Gerome, additional, Chung, Raymond, additional, Curtis, Charles J., additional, Chaudhary, Shabana, additional, Chowdhury, Maharun, additional, Colligan, Grainne, additional, Deloukas, Panos, additional, Durham, Ceri, additional, Durrani, Faiza, additional, Eto, Fabiola, additional, Finer, Sarah, additional, Garcia, Ana Angel, additional, Griffiths, Chris, additional, Harvey, Joanne, additional, Heng, Teng, additional, Huang, Qin Qin, additional, Hurles, Matt, additional, Hunt, Karen A., additional, Hussain, Shapna, additional, Islam, Kamrul, additional, Jacobs, Ben, additional, Khan, Ahsan, additional, Khan, Amara, additional, Lavery, Cath, additional, Lee, Sang Hyuck, additional, Lerner, Robin, additional, MacArthur, Daniel, additional, Malawsky, Daniel, additional, Martin, Hilary, additional, Mason, Dan, additional, Mazid, Mohammed Bodrul, additional, McDermott, John, additional, McSweeney, Sanam, additional, Miah, Shefa, additional, Munir, Sabrina, additional, Newman, Bill, additional, Owor, Elizabeth, additional, Qureshi, Asma, additional, Rahman, Samiha, additional, Safa, Nishat, additional, Solly, John, additional, Tahmasebi, Farah, additional, Trembath, Richard C., additional, Tricker, Karen, additional, Uddin, Nasir, additional, van Heel, David A., additional, Winckley, Caroline, additional, and Wright, John, additional
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- 2023
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25. Cluster Headache Genomewide Association Study and Meta-Analysis Identifies Eight Loci and Implicates Smoking as Causal Risk Factor
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Winsvold, Bendik S., Harder, Aster V. E., Ran, Caroline, Chalmer, Mona A., Dalmasso, Maria Carolina, Ferkingstad, Egil, Tripathi, Kumar Parijat, Bacchelli, Elena, Børte, Sigrid, Fourier, Carmen, Petersen, Anja S., Vijfhuizen, Lisanne S., Magnusson, Sigurdur H., O'Connor, Emer, Bjornsdottir, Gyda, Häppölä, Paavo, Wang, Yen Feng, Callesen, Ida, Kelderman, Tim, Gallardo, Victor J., de Boer, Irene, Olofsgård, Felicia Jennysdotter, Heinze, Katja, Lund, Nunu, Thomas, Laurent F., Hsu, Chia Lin, Pirinen, Matti, Hautakangas, Heidi, Ribasés, Marta, Guerzoni, Simona, Sivakumar, Prasanth, Yip, Janice, Heinze, Axel, Küçükali, Fahri, Ostrowski, Sisse R., Pedersen, Ole B., Kristoffersen, Espen S., Martinsen, Amy E., Artigas, María S., Lagrata, Susie, Cainazzo, Maria Michela, Adebimpe, Joycee, Quinn, Olivia, Göbel, Carl, Cirkel, Anna, Volk, Alexander E., Heilmann-Heimbach, Stefanie, Skogholt, Anne Heidi, Gabrielsen, Maiken E., Wilbrink, Leopoldine A., Danno, Daisuke, Mehta, Dwij, Guðbjartsson, Daníel F., Rosendaal, Frits R., Willems van Dijk, Ko, Fronczek, Rolf, Wagner, Michael, Scherer, Martin, Göbel, Hartmut, Sleegers, Kristel, Sveinsson, Olafur A., Pani, Luca, Zoli, Michele, Ramos-Quiroga, Josep A., Dardiotis, Efthimios, Steinberg, Anna, Riedel-Heller, Steffi, Sjöstrand, Christina, Thorgeirsson, Thorgeir E., Stefansson, Hreinn, Southgate, Laura, Trembath, Richard C., Vandrovcova, Jana, Noordam, Raymond, Paemeleire, Koen, Stefansson, Kari, Fann, Cathy Shen Jang, Waldenlind, Elisabet, Tronvik, Erling, Jensen, Rigmor H., Chen, Shih Pin, Houlden, Henry, Terwindt, Gisela M., Kubisch, Christian, Maestrini, Elena, Vikelis, Michail, Pozo-Rosich, Patricia, Belin, Andrea C., Matharu, Manjit, van den Maagdenberg, Arn M. J. M., Hansen, Thomas F., Ramirez, Alfredo, Zwart, John-Anker, Winsvold, Bendik S., Harder, Aster V. E., Ran, Caroline, Chalmer, Mona A., Dalmasso, Maria Carolina, Ferkingstad, Egil, Tripathi, Kumar Parijat, Bacchelli, Elena, Børte, Sigrid, Fourier, Carmen, Petersen, Anja S., Vijfhuizen, Lisanne S., Magnusson, Sigurdur H., O'Connor, Emer, Bjornsdottir, Gyda, Häppölä, Paavo, Wang, Yen Feng, Callesen, Ida, Kelderman, Tim, Gallardo, Victor J., de Boer, Irene, Olofsgård, Felicia Jennysdotter, Heinze, Katja, Lund, Nunu, Thomas, Laurent F., Hsu, Chia Lin, Pirinen, Matti, Hautakangas, Heidi, Ribasés, Marta, Guerzoni, Simona, Sivakumar, Prasanth, Yip, Janice, Heinze, Axel, Küçükali, Fahri, Ostrowski, Sisse R., Pedersen, Ole B., Kristoffersen, Espen S., Martinsen, Amy E., Artigas, María S., Lagrata, Susie, Cainazzo, Maria Michela, Adebimpe, Joycee, Quinn, Olivia, Göbel, Carl, Cirkel, Anna, Volk, Alexander E., Heilmann-Heimbach, Stefanie, Skogholt, Anne Heidi, Gabrielsen, Maiken E., Wilbrink, Leopoldine A., Danno, Daisuke, Mehta, Dwij, Guðbjartsson, Daníel F., Rosendaal, Frits R., Willems van Dijk, Ko, Fronczek, Rolf, Wagner, Michael, Scherer, Martin, Göbel, Hartmut, Sleegers, Kristel, Sveinsson, Olafur A., Pani, Luca, Zoli, Michele, Ramos-Quiroga, Josep A., Dardiotis, Efthimios, Steinberg, Anna, Riedel-Heller, Steffi, Sjöstrand, Christina, Thorgeirsson, Thorgeir E., Stefansson, Hreinn, Southgate, Laura, Trembath, Richard C., Vandrovcova, Jana, Noordam, Raymond, Paemeleire, Koen, Stefansson, Kari, Fann, Cathy Shen Jang, Waldenlind, Elisabet, Tronvik, Erling, Jensen, Rigmor H., Chen, Shih Pin, Houlden, Henry, Terwindt, Gisela M., Kubisch, Christian, Maestrini, Elena, Vikelis, Michail, Pozo-Rosich, Patricia, Belin, Andrea C., Matharu, Manjit, van den Maagdenberg, Arn M. J. M., Hansen, Thomas F., Ramirez, Alfredo, and Zwart, John-Anker
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Objective The objective of this study was to aggregate data for the first genomewide association study meta-analysis of cluster headache, to identify genetic risk variants, and gain biological insights. Methods A total of 4,777 cases (3,348 men and 1,429 women) with clinically diagnosed cluster headache were recruited from 10 European and 1 East Asian cohorts. We first performed an inverse-variance genomewide association meta-analysis of 4,043 cases and 21,729 controls of European ancestry. In a secondary trans-ancestry meta-analysis, we included 734 cases and 9,846 controls of East Asian ancestry. Candidate causal genes were prioritized by 5 complementary methods: expression quantitative trait loci, transcriptome-wide association, fine-mapping of causal gene sets, genetically driven DNA methylation, and effects on protein structure. Gene set and tissue enrichment analyses, genetic correlation, genetic risk score analysis, and Mendelian randomization were part of the downstream analyses. Results The estimated single nucleotide polymorphism (SNP)-based heritability of cluster headache was 14.5%. We identified 9 independent signals in 7 genomewide significant loci in the primary meta-analysis, and one additional locus in the trans-ethnic meta-analysis. Five of the loci were previously known. The 20 genes prioritized as potentially causal for cluster headache showed enrichment to artery and brain tissue. Cluster headache was genetically correlated with cigarette smoking, risk-taking behavior, attention deficit hyperactivity disorder (ADHD), depression, and musculoskeletal pain. Mendelian randomization analysis indicated a causal effect of cigarette smoking intensity on cluster headache. Three of the identified loci were shared with migraine. Interpretation This first genomewide association study meta-analysis gives clues to the biological basis of cluster headache and indicates that smoking is a causal risk factor. ANN NEUROL, Objective: The objective of this study was to aggregate data for the first genomewide association study meta-analysis of cluster headache, to identify genetic risk variants, and gain biological insights. Methods: A total of 4,777 cases (3,348 men and 1,429 women) with clinically diagnosed cluster headache were recruited from 10 European and 1 East Asian cohorts. We first performed an inverse-variance genomewide association meta-analysis of 4,043 cases and 21,729 controls of European ancestry. In a secondary trans-ancestry meta-analysis, we included 734 cases and 9,846 controls of East Asian ancestry. Candidate causal genes were prioritized by 5 complementary methods: expression quantitative trait loci, transcriptome-wide association, fine-mapping of causal gene sets, genetically driven DNA methylation, and effects on protein structure. Gene set and tissue enrichment analyses, genetic correlation, genetic risk score analysis, and Mendelian randomization were part of the downstream analyses. Results: The estimated single nucleotide polymorphism (SNP)-based heritability of cluster headache was 14.5%. We identified 9 independent signals in 7 genomewide significant loci in the primary meta-analysis, and one additional locus in the trans-ethnic meta-analysis. Five of the loci were previously known. The 20 genes prioritized as potentially causal for cluster headache showed enrichment to artery and brain tissue. Cluster headache was genetically correlated with cigarette smoking, risk-taking behavior, attention deficit hyperactivity disorder (ADHD), depression, and musculoskeletal pain. Mendelian randomization analysis indicated a causal effect of cigarette smoking intensity on cluster headache. Three of the identified loci were shared with migraine. Interpretation: This first genomewide association study meta-analysis gives clues to the biological basis of cluster headache and indicates that smoking is a causal risk factor. ANN NEUROL 2023.
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- 2023
26. A second update on mapping the human genetic architecture of COVID-19
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Kanai, M, Andrews, S, Cordioli, M, Stevens, C, Neale, B, Daly, M, Ganna, A, Pathak, G, Iwasaki, A, Karjalainen, J, Mehtonen, J, Pirinen, M, Chwialkowska, K, Trankiem, A, Balaconis, M, Veerapen, K, Wolford, B, Ahmad, H, von Hohenstaufen Puoti, K, Boer, C, Boua, P, Butler-Laporte, G, Cadilla, C, Chwiałkowska, K, Colombo, F, Douillard, V, Dueker, N, Dutta, A, El-Sherbiny, Y, Eltoukhy, M, Esmaeeli, S, Faucon, A, Fave, M, Cadenas, I, Francescatto, M, Francioli, L, Franke, L, Fuentes, M, Durán, R, Cabrero, D, Harry, E, Jansen, P, Szentpéteri, J, Kaja, E, Kirk, C, Kousathanas, A, Krieger, J, Patel, S, Lemaçon, A, Limou, S, Lió, P, Marouli, E, Marttila, M, Medina-Gómez, C, Michaeli, Y, Migeotte, I, Mondal, S, Moreno-Estrada, A, Moya, L, Nakanishi, T, Nasir, J, Pasko, D, Pearson, N, Pereira, A, Priest, J, Prijatelj, V, Prokić, I, Teumer, A, Várnai, R, Romero-Gómez, M, Roos, C, Rosenfeld, J, Ruolin, L, Schulte, E, Schurmann, C, Sedaghati-khayat, B, Shaheen, D, Shivanathan, I, Sipeky, C, Sirui, Z, Striano, P, Tanigawa, Y, Remesal, A, Vadgama, N, Vallerga, C, van der Laan, S, Verdugo, R, Wang, Q, Wei, Z, Zainulabid, U, Zárate, R, Auton, A, Shelton, J, Shastri, A, Weldon, C, Filshtein-Sonmez, T, Coker, D, Symons, A, Aslibekyan, S, O’Connell, J, Ye, C, Hatoum, A, Agrawal, A, Bogdan, R, Colbert, S, Thompson, W, Fan, C, Johnson, E, Niazyan, L, Davidyants, M, Arakelyan, A, Avetyan, D, Bekbossynova, M, Tauekelova, A, Tuleutayev, M, Sailybayeva, A, Ramankulov, Y, Zholdybayeva, E, Dzharmukhanov, J, Kassymbek, K, Tsechoeva, T, Turebayeva, G, Smagulova, Z, Muratov, T, Khamitov, S, Kwong, A, Timpson, N, Niemi, M, Rahmouni, S, Guntz, J, Beguin, Y, Pigazzini, S, Nkambule, L, Georges, M, Moutschen, M, Misset, B, Darcis, G, Gofflot, S, Bouysran, Y, Busson, A, Peyrassol, X, Wilkin, F, Pichon, B, Smits, G, Vandernoot, I, Goffard, J, Tiembe, N, Morrison, D, Afilalo, J, Mooser, V, Richards, J, Rousseau, S, Durand, M, Forgetta, V, Laurent, L, Afrasiabi, Z, Bouab, M, Tselios, C, Xue, X, Afilalo, M, Oliveira, M, St-Cyr, J, Boisclair, A, Ragoussis, J, Auld, D, Kaufmann, D, Lathrop, G, Bourque, G, Décary, S, Falcone, E, Montpetit, A, Piché, A, Renoux, C, Tremblay, K, Tse, S, Zawati, M, Davis, L, Cox, N, Below, J, Sealock, J, Shuey, M, Polikowsky, H, Petty, L, Shaw, D, Chen, H, Zhu, W, Schmidt, A, Ludwig, K, Maj, C, Rolker, S, Balla, D, Behzad, P, Nöthen, M, Fazaal, J, Keitel, V, Jensen, B, Feldt, T, Marx, N, Dreher, M, Pink, I, Cornberg, M, Illig, T, Lehmann, C, Schommers, P, Rybniker, J, Augustin, M, Knopp, L, Kurth, I, Eggermann, T, Volland, S, Berger, M, Brenner, T, Hinney, A, Witzke, O, Konik, M, Bals, R, Herr, C, Ludwig, N, Walter, J, Latz, E, Schmidt, S, Brooks, J, Bull, S, Elliott, L, Gagnon, F, Greenwood, C, Hung, R, Lawless, J, Paterson, A, Sun, L, Rauh, M, Briollais, L, Gingras, A, Bombard, Y, Pugh, T, Simpson, J, Goneau, L, Halevy, A, Maslove, D, Borgundvaag, B, Devine, L, Bearss, E, Richardson, D, Arnoldo, S, Friedman, S, Taher, A, Stern, S, Dagher, M, Vasilevska-Ristovska, J, Biggs, C, Mickiewicz, B, Strug, L, Scherer, S, Aziz, N, Jones, S, Knoppers, B, Lathrop, M, Turvey, S, Yeung, R, Allen, U, Cheung, A, Herridge, M, Hunt, M, Lerner-Ellis, J, Taher, J, Parekh, R, Hiraki, L, Cowan, J, Ducharme, F, Ostrowski, M, Bernier, F, Kellner, J, Garg, E, Yoo, S, Vlasschaert, C, Frangione, E, Chung, M, Noor, A, Greenfeld, E, Colwill, K, Clausen, M, Chao, G, Yue, F, Fritzler, M, Whitney, J, Thiruvahindrapuram, B, Garant, J, Abraham, R, Davis, A, Campigotto, A, Papenburg, J, Niranjan, K, Betschel, S, Sadarangani, M, Barton-Forbes, M, Hanley, M, Fung, C, Lapadula, E, Macdonald, G, Puopolo, M, Kaushik, D, Nirmalanathan, K, Wong, I, Khan, Z, Zarei, N, Michalowska, M, Modi, B, Persia, P, Estacio, A, Buchholz, M, Cheatley, P, Lorenti, M, Aman, N, Matveev, V, Budylowski, P, Upton, J, Morris, S, Boyd, T, Chowdhary, S, Casalino, S, Morgan, G, Mighton, C, Mcgeer, A, Mazzulli, T, Mcleod, S, Binnie, A, Faghfoury, H, Chertkow, H, Racher, H, Serbanescu, M, Pavenski, K, Esser, M, Thompson, G, Herbrick, J, Gignoux, C, Wicks, S, Crooks, K, Barnes, K, Daya, M, Shortt, J, Rafaels, N, Chavan, S, Schulze, T, Heilbronner, U, Papiol, S, Corbetta, A, Wendtner, C, Spinner, C, Erber, J, Schneider, J, Winter, C, Wiltfang, J, Budde, M, Senner, F, Kalman, J, Protzer, U, Mueller, N, Mousas, A, Liontos, A, Christaki, E, Milionis, H, Tsilidis, K, Asimakopoulos, A, Kanellopoulou, A, Markozannes, G, Biros, D, Milionis, O, Tsourlos, S, Athanasiou, L, Kolios, N, Pappa, C, Papathanasiou, A, Pargana, E, Nasiou, M, Kosmidou, M, Rapti, I, Ntotsikas, E, Chaliasos, K, Ntzani, E, Evangelou, E, Gartzonika, K, Georgiou, I, Tzoulaki, I, Ellinghaus, D, Degenhardt, F, Cáceres, M, Juzenas, S, Lenz, T, Albillos, A, Julià, A, Prati, D, Solligård, E, Garcia, F, Tran, F, Hanses, F, Baselli, G, Zoller, H, Holter, J, Fernández, J, Barretina, J, Valenti, L, Bujanda, L, Buti, M, D’Amato, M, Banales, J, Rosenstiel, P, Koehler, P, Invernizzi, P, de Cid, R, Asselta, R, Schreiber, S, 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C., Thompson, Wesley K., Fan, Chun Chieh, Johnson, Emma C., Niazyan, Lyudmila, Davidyants, Mher, Arakelyan, Arsen, Avetyan, Diana, Bekbossynova, Makhabbat, Tauekelova, Ainur, Tuleutayev, Mukhtar, Sailybayeva, Aliya, Ramankulov, Yerlan, Zholdybayeva, Elena, Dzharmukhanov, Jarkyn, Kassymbek, Kuat, Tsechoeva, Tatyana, Turebayeva, Gulsimzhan, Smagulova, Zauresh, Muratov, Timur, Khamitov, Sadyk, Kwong, Alex S. F., Timpson, Nicholas J., Niemi, Mari E. K., Rahmouni, Souad, Guntz, Julien, Beguin, Yves, Pigazzini, Sara, Nkambule, Lindokuhle, Georges, Michel, Moutschen, Michel, Misset, Benoit, Darcis, Gilles, Gofflot, Stéphanie, Bouysran, Youssef, Busson, Adeline, Peyrassol, Xavier, Wilkin, Françoise, Pichon, Bruno, Smits, Guillaume, Vandernoot, Isabelle, Goffard, Jean-Christophe, Tiembe, Nicky, Morrison, David R., Afilalo, Jonathan, Mooser, Vincent, Richards, J. 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Tsourlos, Stavros, Athanasiou, Lazaros, Kolios, Nikolaos-Gavriil, Pappa, Christiana, Papathanasiou, Alexandros, Pargana, Eleni, Nasiou, Maria, Kosmidou, Maria, Rapti, Iro, Ntotsikas, Evangelos, Chaliasos, Konstantinos, Ntzani, Evangelia, Evangelou, Evangelos, Gartzonika, Konstantina, Georgiou, Ioannis, Tzoulaki, Ioanna, Ellinghaus, David, Degenhardt, Frauke, Cáceres, Mario, Juzenas, Simonas, Lenz, Tobias L., Albillos, Agustín, Julià, Antonio, Prati, Daniele, Solligård, Erik, Garcia, Federico, Tran, Florian, Hanses, Frank, Baselli, Guido, Zoller, Heinz, Holter, Jan Cato, Fernández, Javier, Barretina, Jordi, Valenti, Luca, Bujanda, Luis, Buti, Maria, D’Amato, Mauro, Banales, Jesus M., Rosenstiel, Philip, Koehler, Philipp, Invernizzi, Pietro, de Cid, Rafael, Asselta, Rosanna, Schreiber, Stefan, Duga, Stefano, Hehr, Ute, Franke, Andre, Maya-Miles, Douglas, Hov, Johannes R., Karlsen, Tom H., Folseraas, Trine, Teles, Ana, Tanck, Anja, Gassner, Christoph, Azuure, Clinton, Wacker, Eike 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Valsecchi, Maria G., Hernandez-Tejero, María, Vehreschild, Maria J. G. T., Manunta, Maria, Acosta-Herrera, Marialbert, D’Angiò, Mariella, Baldini, Marina, Cazzaniga, Marina, Marquié, Marta, Castoldi, Massimo, Cecconi, Maurizio, Tomasi, Melissa, Boada, Mercè, Joannidis, Michael, Mazzocco, Michela, Ciccarelli, Michele, Rodríguez-Gandía, Miguel, Bocciolone, Monica, Miozzo, Monica, Ayo, Natale Imaz, Blay, Natalia, Chueca, Natalia, Montano, Nicola, Martínez, Nilda, Cornely, Oliver A., Palmieri, Orazio, Faverio, Paola, Preatoni, Paoletta, Bonfanti, Paolo, Omodei, Paolo, Tentorio, Paolo, Castro, Pedro, Rodrigues, Pedro M., Izquierdo-Sanchez, Laura, España, Pedro Pablo, Hoffmann, Per, Bacher, Petra, de Pablo, Raúl, Ferrer, Ricard, Gualtierotti, Roberta, Gallego-Durán, Rocío, Nieto, Rosa, Carpani, Rossana, Morilla, Rubén, Badalamenti, Salvatore, Haider, Sammra, Ciesek, Sandra, Bombace, Sara, Marsal, Sara, Klein, Sebastian, Pelusi, Serena, Wilfling, Sibylle, Goerg, Siegfried, Bosari, Silvano, Brunak, Søren, Heilmann-Heimbach, Stefanie, Aliberti, Stefano, Dudman, Susanne, Zheng, Tenghao, Bahmer, Thomas, Pumarola, Tomas, Cejudo, Trinidad Gonzalez, Rimoldi, Valeria, Monzani, Valter, Skogen, Vegard, Friaza, Vicente, Andrade, Victor, Moreno, Victor, Peter, Wolfgang, Farre, Xavier, Khodamoradi, Yascha, Grimsrud, Marit M., May, Sandra, Colombo, Alicia, Virginia, Monardes-Ramírez A., Dorador, Cristina, Fuentes-Guajardo, Macarena, Silva, Andrea X., Espinosa-Parrilla, Yolanda, Yáñez, Cristian E., Retamales-Ortega, Rocío M., Saez Hidalgo, Juan M., Tobar-Calfucoy, Eduardo A., Carvajal-Silva, Laura, Martínez, Matías F., Cerpa, Leslie C., Christian, Muñoz A., Cappelli, Claudio, Valenzuela-Jorquera, Hector, Zapata-Contreras, Daniela, Zuñiga-Pacheco, Paula, Nova-Lamperti, Estefania A., Sanhueza, Sergio A., Donoso, Gerardo, Bocchieri, Pamela, Kochifas, Pia, Quiñones, Luis A., Pedersen, Ole Birger, Geller, Frank, Westergaard, David, Sequeros, Celia Burgos, Nissen, Janna, Nielsen, Susanne Dam, Feldt-Rasmussen, Ulla, Bliddal, Sofie, Grønbæk, Kirsten, Ullum, Henrik, Ostrowski, Sisse Rye, Feenstra, Bjarke, Shahin, Doaa, Sobh, Ali, Shoma, Ashraf, Nkambul, Lindokuhle, Elhadidy, Tamer A., Abd Elghafar, Mohamed S., El-Jawhari, Jehan J., Mohamed, Attia A. S., Elnagdy, Marwa H., Samir, Amr, Abdel-Aziz, Mahmoud, Khafaga, Walid T., El-Lawaty, Walaa M., Torky, Mohamed S., El-Shanshory, Mohamed R., Elzeiny, Ahmed, Rashad, Amal, Mansour, Tamer A., Yassen, Amr M., Hegazy, Mohamed A. F., Okasha, Kamal, Eid, Mohammed A., Hanteera, Moahmed S., Medina-Gomez, Carolina, Ikram, M. Arfan, Uitterlinden, Andre G., Ripatti, Samuli, Jermy, Bradley, Ruotsalainen, Sanni, Kristiansson, Kati, Koskelainen, Sami, Perola, Markus, Donner, Kati, Kivinen, Katja, Palotie, Aarno, Kaunisto, Mari, Julienne, Hanna, Aschard, Hugues, Deleuze, Jean-Francois, Debette, Stephanie, Tregouet, David-Alexandre, Abel, Laurent, Henches, Léo, Lefloch, Edith, Claire, Dandine-Roulland, Sakuntabhai, Anavaj, Bourgeron, Thomas, Olaso, Robert, Daian, Delphine Bacq, Pellegrin, Isabelle, Casanova, Jean-Laurent, Cobat, Aurélie, Jouanguy, Emmanuelle, Zhang, Qian, Ghosn, Jade, Mentré, France, Laouénan, Cédric, Tubiana, Sarah, Chirouze, Catherine, Quintana-Murci, Luis, Patin, Etienne, Duffy, Darragh, Boland, Anne, Carreras, Anna, Galván-Femenía, Iván, Farré, Xavier, Cortés, Beatriz, Mercader, Josep Maria, Guindo-Martinez, Marta, Torrents, David, Garcia-Aymerich, Judith, Castaño-Vinyals, Gemma, Dobaño, Carlota, van Heel, David A., Hunt, Karen A., Trembath, Richard C., Jacobs, Benjamin Meir, Huang, Qin Qin, Martin, Hilary C., Mason, Dan, Trivedi, Bhavi, Wright, John, Munisamy, Malathy, Finer, Sarah, Griffiths, Christopher J., McCarthy, Mark I., Rosenberger, Carrie, Lee, Jong Eun, Chang, Diana, Hammer, Christian, Hunkapiller, Julie, Mahajan, Anubha, Pendergrass, Rion, Sucheston-Campbell, Lara, Yaspan, Brian, Lee, Hyun Soo, Shin, Eunsoon, Jang, Hye Yoon, Kim, Sunmie, Kym, Sungmin, Kim, Yeon-Sook, Jeong, Hyeongseok, Kwon, Ki Tae, Kim, Shin-Woo, Kim, Jin Yong, Jang, Young Rock, Kim, Hyun ah, Lee, Ji yeon, Lee, Jeong Eun, Lee, Shinwon, Choe, Kang-Won, Kang, Yu Min, Jee, Sun Ha, Jung, Keum Ji, Park, Hyun-Young, Kim, Bong-Jo, Kim, Young Jin, Hwang, Mi Yeong, Yoon, Kyungheon, Pairo-Castineira, Erola, Rawlik, Konrad, Caulfield, Mark J., Baillie, J. Kenneth, Griffiths, Fiona, Bretherick, Andrew D., Stuckey, Alex, Odhams, Christopher A., Walker, Susan, Russell, Clark D., Malinauskas, Tomas, Wu, Yang, Shen, Xia, Elliott, Katherine S., Morrice, Kirstie, Keating, Sean, Wang, Bo, Rhodes, Daniel, Klaric, Lucija, Zechner, Marie, Parkinson, Nick, Fawkes, Angie, Murphy, Lee, Vitart, Veronique, Wilson, James F., Yang, Jian, Scott, Richard H., Moutsianas, Loukas, Law, Andy, Begg, Colin, Hendry, Sara Clohisey, Hinds, Charles, Horby, Peter, Knight, Julian, Ling, Lowell, Maslove, David, McAuley, Danny, Millar, Johnny, Montgomery, Hugh, Nichol, Alistair, Openshaw, Peter J. M., Ponting, Chris P., Rowan, Kathy, Semple, Malcolm G., Shankar-Hari, Manu, Summers, Charlotte, Walsh, Timothy, Pan, Jacqueline, Grau, Neus, Jones, Tim Owen, Lim, Rosario, Marotti, Martina, Whitton, Christopher, Bociek, Aneta, Campos, Sara, Arbane, Gill, Ostermann, Marlies, Cha, Mina, DAmato, Fabiola, Kosifidou, Eirini, Lorah, Shelley, Morera, Kyma, Brady, Laura, Hugill, Keith, Henning, Jeremy, Bonner, Stephen, Headlam, Evie, Jones, Jessica, List, Abigail, Morley, Joanne, Welford, Amy, Kamangu, Bobette, Ratnakumar, Anitha, Shoremekun, Abiola, Alldis, Zoe, Astin-Chamberlain, Raine, Bibi, Fatima, Biddle, Jack, Blow, Sarah, Bolton, Matthew, Borra, Catherine, Bowles, Ruth, Burton, Maudrian, Choudhury, Yasmin, Cox, Amber, Easthope, Amy, Ebano, Patrizia, Fotiadis, Stavros, Gurasashvili, Jana, Halls, Rosslyn, Hartridge, Pippa, Kallon, Delordson, Kassam, Jamila, Lancoma-Malcolm, Ivone, Matharu, Maninderpal, May, Peter, Mitchelmore, Oliver, Newman, Tabitha, Patel, Mital, Pheby, Jane, Pinzuti, Irene, Prime, Zoe, Prysyazhna, Oleksandra, Shiel, Julian, Taylor, Melanie, Tierney, Carey, Zongo, Olivier, Wood, Suzanne, Zak, Anne, Collier, David, Mundy, Manuela, Thompson, Christopher, Pritchard, Lisa, Gellamucho, Minnie, Cartlidge, David, Bandla, Nageswar, Bailey, Lucy, Davies, Michelle, Delaney, Jane, Scott, Leanne, Abdelrazik, Marwa, Alasdair, Frater, Carter, David, Elhassan, Munzir, Ganesan, Arunkumar, Jenkins, Samuel, Lamond, Zoe, Purohit, Dharam, Rohit, Kumar, Saleem, Malik, Wall, Alanna, Xavier, Kugan, Bakthavatsalam, Dhanalaksmi, Gehad, Kirolos, Gnanapragasam, Pakeerathan, Jain, Kapil, Jain, Swati, Malik, Abdul, Pappachan, Naveen, Moreno-Cuesta, Jeronimo, Haldeos, Anne, Vincent, Rachel, Oziegb, Maryjane, Cavazza, Anna, Cockrell, Maeve, Corcoran, Eleanor, Depante, Maria, Finney, Clare, Jerome, Ellen, Knighton, Abigail, Nayak, Monalisa, Pappa, Evita, Saha, Rohit, Saha, Sian, Dodd, Andrew, O’Reilly, Kevin, McPhail, Mark, Clarey, Emma, Noble, Harriet, Smith, John, Coghlan, Phoebe, Brett, Stephen, Gordon, Anthony, Templeton, Maie, Antcliffe, David, Banach, Dorota, Darnell, Sarah, Fernandez, Ziortza, Jepson, Eleanor, Mohammed, Amal, Rojo, Roceld, Arias, Sonia Sousa, Gurung, Anita Tamang, Wong, Jenny, Fernandez-Roman, Jaime, Hamilton, David O., Johnson, Emily, Johnston, Brian, Martinez, Maria Lopez, Mulla, Suleman, Waite, Alicia A. C., Williams, Karen, Waugh, Victoria, Welters, Ingeborg, Emblem, Jessica, Norris, Maria, Shaw, David, Bashyal, Archana, Beer, Sally, Hutton, Paula, McKechnie, Stuart, Davidson, Neil, Mathew, Soya, Readion, Grace, Ryu, Jung, Wilson, Jean, Agrawal, Shruti, Elston, Kay, Jones, Megan, Meaney, Eoghan, Polgarova, Petra, Elbehery, Muhammad, Daubney, Esther, Ng, Anthony, Marshall, Jocelyn, Pathan, Nazima, Stroud, Katerina, White, Deborah, Andrew, Angela, Ashraf, Saima, Clark, Amy, Dent, Martin, Langley, Margaret, Peters, Cecilia, Ryan, Lucy, Sampson, Julia, Wei, Shuying, Baddeley, Alice, Meredith, Megan, Morris, Lucy, Gibbons, Alexandra, McLoughlin, Lisa, Delgado, Carlos Castro, Clark, Victoria, Dawson, Deborah, Ding, Lijun, Durrant, Georgia, Ezeobu, Obiageri, Harrison, Abiola, Hurt, William James, Kanu, Rebecca, Kinch, Ashley, Leaver, Susannah, Lisboa, Ana, Mathew, Jisha, Patel, Kamal, Saluzzio, Romina Pepermans, Rawlins, John, Samakomva, Tinashe, Shah, Nirav, Sicat, Christine, Texeira, Joana, Queiroz, Joana Gomes De, Gloria, Edna Fernandes Da, Maccacari, Elena, Yun, Nikki, Manna, Soumendu, Farnell-Ward, Sarah, Maizcordoba, Maria, Thanasi, Maria, Ali, Hawakin Haji, Hastings, Janice, Grauslyte, Lina, Hussain, Musarat, Ruge, Bobby, King, Sam, Pogreban, Tatiana, Rosaroso, Lace, Smith, Helen, Phull, Mandeep-Kaur, Adams, Nikkita, Franke, George, George, Aparna, Salciute, Erika, Wong, Joanna, Dunne, Karen, Flower, Luke, Sharland, Emma, Sra, Sukhmani, Andrew, Gillian, Callaghan, Marie, Barclay, Lucy, Marshall, Lucy, Amamio, Maria, Birch, Sophie, Briton, Kate, Clark, Sarah, Doverman, Katerine, Hope, Dave, Mcculloch, Corrienne, Simpson, Scott, Singleton, Jo, Fernandez, Rita, Allen, Meryem, Baptista, David, Crowe, Rebecca, Fox, Jonathan, Khera, Jacyntha, Loveridge, Adam, McKenley, India, Morino, Eriko, Naranjo, Andres, O’Connor, Denise, Simms, Richard, Sollesta, Kathryn, Swain, Andrew, Venkatesh, Harish, Herdman-Grant, Rosie, Joseph, Anna, Nown, Angela, Rose, Steve, Pogson, David, Boxall, Helen, Brimfield, Lutece, Claridge, Helen, Daly, Zoe, George, Shenu, Gribbin, Andrew, Cheema, Yusuf, Cutler, Sean, Richards, Owen, Roynon-Reed, Anna, Cherian, Shiney, Heron, Anne Emma, Williams, Gemma, Szakmany, Tamas, Waters, Abby, Collins, Kim, Dunhill, Jill, Jones, Ffion, Morris, Rebecca, Ship, Lucy, Cardwell, Amy, Ali, Syamlan, Bhatterjee, Ravi, Bolton, Rachel, Chukkambotla, Srikanth, Coleman, Dabheoc, Dalziel, Jack, Dykes, Joseph, Fine, Christopher, Gay, Bethan, Goddard, Wendy, Goodchild, Drew, Harling, Rhiannan, Hijazi, Muhammad, Keith, Sarah, Khan, Meherunnisa, Matt, Roseanna, Ryan-Smith, Janet, Saad, Samuel, Springle, Philippa, Thomas, Jacqueline, Truman, Nick, Kazi, Aayesha, Smith, Matthew, Collier, Heather, Davison, Chloe, Duberley, Stephen, Hargreaves, Jeanette, Hartley, Janice, Patel, Tahera, Smith, Ellen, Kent, Alissa, Goodwin, Emma, Zaki, Ahmed, Tibke, Clare, Hopkins, Susan, Gerrard, Hywel, Jackson, Matthew, Bennett, Sara, Marsh, Liane, Mills, Rebecca, Bell, Jessica, Campbell, Helen, Dawson, Angela, Dodds, Steve, Duffy, Stacey, Gallagher, Lisa, McCafferty, Gemma, Short, Stacey, Smith, Tracy, Thomas, Kirsty, Walker, Claire, Reynolds, Jessica, Yates, Bryan, McKie, Hayley, Panteli, Maria, Thompson, Maria, Waddell, Gail, Beger, Sarah De, Abraheem, Azmerelda, Dunmore, Charlie, Girach, Rumanah, Jones, Rhianna, London, Emily, Nagra, Imrun, Nasir, Farah, Sainsbury, Hannah, Smedley, Clare, Brearey, Stephen, Burchett, Caroline, Cawley, Kathryn, Faulkner, Maria, Jeffrey, Helen, Bamford, Peter, Shaikh, Firdaus, Slack, Lauren, Davies, Angela, Brooke, Hollie, Suarez, Jose Cebrian, Charlesworth, Ruth, Hansson, Karen, Norris, John, Poole, Alice, Sandhu, Rajdeep, Smithson, Elizabeth, Thirumaran, Muthu, Wagstaff, Veronica, Buckley, Sarah, Sloan, Brendan, Rose, Alastair, Major, Amy, Metcalfe, Alexandra, Almaden-Boyle, Christine, Austin, Pauline, Chapman, Susan, Eros, Alexandre, Cabrelli, Louise, Cole, Stephen, Whyte, Clare, Casey, Matt, Bafitis, Vasileios, Tsinaslanidis, George, George, Cassandra, Khade, Reena, Black, Christopher, Ashok, Sundar Raj, Farley, Sean, Brinkworth, Elaine, Harford, Rachel, Murphy, Carl, Williams, Marie, Newey, Luke, Toghill, Hannah, Lewis, Sophie, Rees, Tabitha, Battle, Ceri, Baker, Mark, Travers, Jenny, Chesters, Karen, Baxter, Nicola, Arnott, Andrew, McCreath, Gordan, McParland, Christopher, Rooney, Laura, Sim, Malcolm, Henderson, Steven, Abel, Lynn, Dalton, Carol, Kennedy-Hay, Sophie, O’Donohoe, Lynn, O’Hare, Megan, Orlikowska, Izabela, Parker, Natasha, McNeela, Fiona, Lyle, Amanda, Hughes, Alistair, Radhakrishnan, Jayachandran, Gibson, Sian, Bancroft, Hollie, Bellamy, Mary, Daglish, Jacqueline, Kadiri, Salma, Moore, Faye, Rhodes, Joanne, Sangombe, Mirriam, Peterkin, Zhane, Scriven, James, Carmody, Margaret, Cottle, Juliet, Peasgood, Emily, de Gordoa, Laura Ortiz-Ruiz, Phillips, Claire, Skinner, Denise, Cinquina, Zoe, Howard, Kate, Joy, Rosie, Roche, Samantha, Birkinshaw, Isobel, Carter, Joseph, Ingham, Jo, Marshall, Nicola, Pearson, Harriet, Scott, Zoe, Dasgin, Jo, Gill, Jaspret, Nilsson, Annette, Bamford, Amy, Hull, Diana, Ahmadhaider, Nafeesah, Bates, Michelle, McGhee, Christopher, Ellis, Hannah, Howe, Gwenllian Sera, Singh, Jayaprakash, Stroud, Natalie, Roche, Lisa, Lynch, Ceri, Deacon, Bethan, Pothecary, Carla, Smeaton, Justyna, Agravante, Kevin, Krishnamurthy, Vinodh, Diaba, Cynthia, John, Lincy, Lim, Lai, Jha, Rajeev, Egan, Jasmine, Felton, Timothy, Glasgow, Susannah, Padden, Grace, Choudhr, Ozerah, Bradley-Potts, Joanne, Moss, Stuart, Lingeswaran, Saejohn, Alexander, Peter, Brandwood, Craig, Fiouni, Sofia, Ward, Luke, Allen, Schvearn, Shaw, Jane, Smith, Christopher, Adanini, Oluronke, Collins, Rebecca, Msiska, Maines, Ofori, Linda, Bhatia, Nikhil, Dolan, Hayley, Brunton, Mark, Caterson, Jess, Coles, Holly, Keating, Liza, Tilney, Emma, Jacques, Nicola, Frise, Matthew, Armistead, Jennifer, Bartley, Shauna, Bhuie, Parminder, Rai, Sabi, Tomkova, Gabriela, Greer, Sandra, Shuker, Karen, Tridente, Ascanio, Dobson, Emma, Hunt, Jodie, Tully, Redmond, Dearden, Joy, Drummond, Andrew, Kamath, Prakash, Bullock, Emily, Mulcahy, Michelle, Munt, Shelia, O’Connor, Grainne, Philbin, Jennifer, Rishton, Chloe, Scott, Chloe, Winnard, Sarah, Hasni, Nurkamalia, Gascoyne, Rachel, Hawes, Joanne, Pritchard, Kelly, Stevenson, Lesley, Whileman, Amanda, Beavis, Sarah, Bishop, Lauren, Cart, Cindy, Dale, Katie, Kelly-Baxter, Mary, Mendelski, Adam, Moakes, Emma, Smith, Rheanna, Woodward, Jan, Wright, Stephanie, Allan, Angela, Botello, Adriana, Liew, Jade, Medhora, Jasmine, Trumper, Erin, Savage, Felicity, Scott, Teresa, Place, Marc, Kaye, Callum, Benyon, Sarah, Marriott, Suzie, Park, Linda, Quinn, Helen, Skyes, Daisy, Zitter, Lily, Baines, Kizzy, Gordon, Elizabeth, Keenan, Samantha, Pitt, Andrew, Duffy, Katharine, Ireland, Jane, Semple, Gary, Turner, Lynne, Cathcart, Susanne, Rimmer, Dominic, Puxty, Alex, Puxty, Kathryn, Hurst, Andrew, Miller, Jennifer, Speirs, Susan, Walker, Lauren, Bradshaw, Zena, Brown, Joanna, Melling, Sarah, Preston, Stephen, Slawson, Nicola, Warden, Scott, Beasley, Alanna, Stoddard, Emma, Benham, Leonie, Cupitt, Jason, Caswell, Melanie, Elawamy, Lisa, Wignall, Ashleigh, Roberts, Belinda, Golding, Hannah, Leggett, Samantha, Male, Michelle, Marani, Martyna, Prager, Kirsty, Williams, Toran, Golder, Kim, Jones, Oliver, Cusack, Rebecca, Bolger, Clare, Burnish, Rachel, Carter, Michael, Jackson, Susan, Salmon, Karen, Biss, Jonathan, Aquino, Maia, Croft, Maria, Frost, Victoria, White, Ian, Govender, Keshnie, Webb, Natasha, Stapleton, Liana, Wells, Colin, Nikitas, Nikitas, Sanchez - Rodriguez, Ana, Spencer, Kayleigh, Stowe, Bethan, Izzard, Yvonne, Poole, Michelle, Monnery, Sonja, Trotman, Sallyanne, Beech, Valerie, Combes, Edward, Joefield, Teishel, Covernton, Patrick, Savage, Sarah, Woodward, Elizabeth, Camsooksai, Julie, Reschreiter, Henrik, Barclay, Charlotte, DeAth, Yasmin, Dube, Judith, Humphrey, Charlotte, Jenkins, Sarah, Langridge, Emma, Milne, Rebecca, Wadams, Beverley, Woolcock, Megan, Brett, Michael, Digby, Brian, Gemmell, Lisa, Hornsby, James, MacGoey, Patrick, O’Neil, Pauline, Price, Richard, Sundaram, Radha, Rodden, Natalie, Thomson, Nicola, Rooney, Kevin, Currie, Susan, Henderson, Philip, Ogg, Bethan, Whiteley, Simon, Wilby, Liz, Long, Kate, Matthew, Shailamma, Salada, Sheila, Trott, Susan, Watts, Sarah, Friar, Zoe, Speight, Abigail, Bastion, Victoria, Chandna, Humza, Djeugam, Brice, Haseeb, Muhammad, Kent, Harriet, Lubimbi, Gamu, Murdoch, Sophie, Thomas, Alastair, David, Beena, Lorusso, Rachel, Vochin, Ana, Penacerrada, Melchizedek, Wulandari, Retno, Heath, Charlotte, Jakkula, Srinivas, Morris, Anna, Ahmed, Ashar, Nune, Arvind, Buttriss, Claire, Whitaker, Emma, Davey, Miriam, Golden, David, Acklery, Amy, Fernandes, Fabio, Seaman, Bec, Earl, Victoria, Collins, Amy, Khaliq, Waqas, Adam, Rachel, Treus, Estefania, Holland, Sarah, Alfonso, Jordan, Blackledge, Bethan, Bruce, Michelle, Durrans, Laura Jayne, Eltayeb, Ayaa, Harris, Jade, Hey, Samuel, Hruska, Martin, Lamb, Thomas, Rothwell, Joanne, Fitzgerald, Adele, Lindergard, Gabriella, T-Michael, Helen, Duncan, Tracey, Baxter-Dore, Sharon, Cooper, Lisa, Fox, Claire, Guerin, Jacinta, Hodgkiss, Tracey, Connolly, Karen, McAlinden, Paul, Bridgett, Victoria, Fearby, Maggie, Gulati, A., Hanson, Helen, Kelly, Sinead, McCormack, Louise, Nixon, Rachel, Robinson, Philip, Slater, Victoria, Stephenson, Elaine, Webster, Andrea, Webster, K., Hays, Carole, Hudson, Anne, Patel, Bijal, Clement, Ian, Davis, John, Francis, Sarah, Jerry, Douglas, Abernathy, Caroline, Foster, Louise, Gratrix, Andrew, Cabral-Ortega, Llucia, Hines, Matthew, Martinson, Victoria, Stones, Elizabeth, Winter, Karen, Barrow, Esther, Wylie, Katharine, Baines, Deborah, Birchall, Katie, Kolakaluri, Laurel, Clark, Richard, Sukumaran, Anila, Barker, Melanie, Paripoorani, Deborah, Smith, Lara, Taylor, Charlotte, Downes, Charlotte, Hayman, Melanie, Riches, Katie, Daniel, Priya, Subramanian, Deepak, Holding, Kathleen, Hilton, Mary, Mcdonald, Carly, Richardson, Georgina, Halladay, Georgia, Harding, Peter, Reddy, Amie, Turner-Bone, Ian, Wilding, Laura, Parker, Robert, Lloyd, Michaela, Smith, Leanne, Kelly, Charlie, Lazo, Maria, Neal, Alan, Walton, Olivia, Melville, Julie, Naisbitt, Jay, Joseph, Rosane, Callam, Sara, Hudig, Lisa, Keshet-Price, Jocelyn, Stammers, Katie, Convery, Karen, Randell, Georgina, Fottrell-gould, Deirdre, Mwaura, Esther, Sutherland, Sara-Beth, Stewart, Richard, Mew, Louise, Wren, Lynn, Thrasyvoulou, Laura, Willis, Heather, Hopkins, Bridget, Lenton, Daniel, Roberts, Abigail, Bokhari, Maria, Lucas, Rachael, McCormick, Wendy, Ritzema, Jenny, Linnett, Vanessa, Sanderson, Amanda, Wild, Helen, Flanagan, Rebecca, Hull, Robert, Rhead, Kat, McKenna, Emma, Hughes, Gareth, Anderson, Jennifer, Jones, Kelly, Latham, Scott, Riley, Heather, Coulding, Martina, Clark, Martyn, McCormick, Jacqueline, Mercer, Oliver, Potla, Darsh, Rehman, Hafiz, Savill, Heather, Turner, Victoria, Jude, Edward, Kilroy, Susan, Apetri, Elena, Basikolo, Cathrine, Catlow, Laura, Collis, Matthew, Doonan, Reece, Harvey, Alice, Knowles, Karen, Lee, Stephanie, Lomas, Diane, Lyons, Chloe, McMorrow, Liam, Michael, Angiy, Pendlebury, Jessica, Perez, Jane, Poulaka, Maria, Proudfoot, Nicola, Slevin, Kathryn, Thomas, Vicky, Walker, Danielle, Dark, Paul, Charles, Bethan, McLaughlan, Danielle, Slaughter, Melanie, Horner, Dan, Marsden, Tracy, Andrews, Joyann, Beech, Emily, Akinkugbe, Olugbenga, Bamford, Alasdair, Belfield, Holly, Jones, Gareth A. L., McHugh, Tara, Meghari, Hamza, Ray, Samiran, Tomas, Ana Luisa, O’Neill, Lauran, Peters, Mark, Bell, Michael, Benkenstein, Sarah, Chisholm, Catherine, Davies, Charlene, Kupiec, Klaudia, Payne, Caroline, Halls, Joanna, Blakemore, Hayley, Goff, Elizabeth, Hayes, Kati, Smith, Kerry, Stephens, Deanna, Worner, Ruth, Borislavova, Borislava, Faulkner, Beverley, Thomas, Matt, Cookson, Ruth, Gendall, Emma, Larman, Georgina, Pope, Rebecca, Smalira, Artur, Priestley, Victoria, Cosier, Tracey, Millen, Gemma, Rand, James, Schumacher, Natasha, Sandhar, Roxana, Weston, Heather, Richardson, Neil, Cooper, Lucy, Jones, Cathy, Huang, Ya-Wen Jessica, Jacob, Reni, Denmade, Craig, Mcintyre, Lewis, Trodd, Dawn, Martin, Jane, Watson, Geoff, Bevan, Emily, Wreybrown, Caroline, Bano, Shereen, Bellwood, Ruth, Bentley, Michael, Bromley, Matt, Gurr, Lucy, Ledgard, Camilla, McGowan, Janet, Pye, Kate, Sellick, Kirsten, Stacey, Amelia, Warren, Deborah, Wilkinson, Brian, Akeroyd, Louise, Shafique, Huma, Morgan, James, Shorter, Susan, Swinger, Rachel, Waters, Emily, Lawton, Tom, Allan, Elizabeth, Darlington, Kate, Davies, Ffyon, Davies, Llinos, Easton, Jack, Kumar, Sumit, Lean, Richard, Mackay, Callum, Pugh, Richard, Qiu, Xinyi, Rees, Stephanie, Scanlon, Jeremy, Lewis, Joanne, Menzies, Daniel, Bolger, Annette, Davies, Gwyneth, Davies, Jennifer, Garrod, Esther, Jones, Helen, Manley, Rachel, Williams, Hannah, Frankham, Jordan, Pitts, Sally, White, Nigel, Branney, Debbie, Tiller, Heather, Efford, Georgia, Garland, Zoe, Grimmer, Lisa, Gumbrill, Bethany, Johnson, Rebekah, Sweet, Katie, Bewley, Jeremy, Coleman, Christina, Corcoran, Katie, Morano, Eva Maria Hernandez, Shiel, Rachel, Webster, Denise, Bonnici, Josephine, Daniel, Eleanor, Dell, Abbie, Kent, Melanie, Wilkinson, Ami, Brown, Ellen, Kay, Andrea, Campbell, Suzanne, Cowton, Amanda, Birt, Mark, Greenaway, Vicki, Potts, Kathryn, Hutton, Clare, Shepperson, Andrew, Forsey, Miranda, Nicholson, Alice, Vertue, Mark, Riches, Joanne, Kaliappan, Agilan, Nicholson, Anne, MacCallum, Niall, Raith, Eamon, Bercades, Georgia, Hass, Ingrid, Brealey, David, Martir, Gladys, Reyes, Anna, Smyth, Deborah, Zapatamartinez, Maria, Alvaro, Ana, Jetha, Champa, Ma, Louise, Booker, Lauren, Mostoles, Loreta, Pratley, Anezka, Altabaibeh, Abdelhakim, Parmar, Chetan, Gilbert, Kayleigh, Ferguson, Susie, Shepherd, Amy, Morris, Sheila, Baruah, Rosie, Lloyd, Georgina, Bell, Stephanie, Rivers, Vanessa, Purewal, Bally, Hammerton, Kate, Anderson, Susan, Birch, Janine, Collins, Emma, Oleary, Ryan, Cornell, Sarah, Jarmain, Jordan, Rogerson, Kimberley, Wakinshaw, Fiona, Woods, Lindsey, Rostron, Anthony, Elcioglu, Zeynep, Roy, Alistair, Bell, Gillian, Dickson, Holly, Wilcox, Louise, Katary, Amro, English, Katy, Hutter, Joanne, Pawley, Corinne, Doble, Patricia, Shovelton, Charmaine, Vaida, Marius, Purnell, Rebecca, Thomas, Ashly, Cagova, Lenka, Fofano, Adama, Holcombe, Helen, Mitchell, Alice Michael, Mwaura, Lucy, Praman, KrithivasanÂ, Garnr, Lucie, Mepham, Sue, Paques, Kitty, Vuylsteke, Alain, Mackie, Jennifer, Pearn, Carmen, Zamikula, Julie, Nyirenda, Maggie, Capozzi, Lisa, Reece-Anthony, Rosie, Noor, Hazma, Nilo, Alfa Cresia, Grove, Michelle, Daniel, Amelia, Finn, Joanne, White, Nikki, Saha, Rajnish, Badal, Bibi, Ixer, Karen, Duffin, Donna, Player, Ben, Hill, Helen, Cole, Jade, Brooks, Jenny, Davies, Rhys, Hunt, Lauren, Thomas, Emma, Williams, Angharad, Oblak, Metod, Thankachen, Mini, Irisari, Jamie, Sayan, Amrinder, Popescu, Monica, Finch, Cheryl, Jamieson, Andrew, Quinn, Alison, Cooper, Joshua, Liderth, Sarah, Waddington, Natalia, Burn, Iona, Manso, Katarina, Penn, Ruth, Tebbutt, Julie, Thornton, Danielle, Winchester, James, Hambrook, Geraldine, Shanmugasundaram, Pradeep, Craig, Jayne, Simpson, Kerry, Higham, Andrew, Sibbett, Louise, Paine, Sheila, Reed, Annabel, Conyngham, Jo-Anna, Mupudzi, Mcdonald, Thomas, Rachel, Wright, Mary, Griffin, Denise, Partridge, Richard, Corral, Maria Alvarez, Muchenje, Nycola, Sitonik, Mildred, Butler, Aaron, Folkes, Linda, Fox, Heather, Gardner, Amy, Helm, David, Hobden, Gillian, King, Kirsten, Margalef, Jordi, Margarson, Michael, Martindale, Tim, Meadows, Emma, Raynard, Dana, Thirlwall, Yvette, Baird, Yolanda, Gomez, Raquel, Martin, Darren, Hodgson, Luke, Corin, Clinton, Sidall, Erikka, Szabo, Densie, Floyd, Sharon, Davies, Hannah, Austin, Karen, Kelsall, Olivia, Wood, Hannah, Cornell, Thomas, Ralph, Kate, Bean, Sarah, Burt, Karen, Spivey, Michael, Richards, Carol, Tedstone, Rachel, Carmody, Siobhain, Zhao, Xiaobei, Page, Valerie, Guanco, Mark Louie, Hoxha, Elvira, Zorloni, Camilla, Dean, Charlotte, Jones, Emma, Carter, Emma, Dunn, Joshua, Kong, Thomas, Mahenthran, Mervin, Marsh, Chris, Holland, Maureen, Keenan, Natalie, Mahmoud, Mohamed, Lyons, Marc, Wassall, Helen, Young, Meghan, Bradley, Paul, Burda, Dorota, Donlon, Sinead, Harden, Lesley, Harris, Celia, Mayangao, Irving, Montaser, Rugia, Mtuwa, Sheila, Piercy, Charles, Smith, Eleanor, Stone, Sarah, Verula, Jerik, Blackman, Helen, Marriott, Cheryl, Michalak, Natalia, Creagh-Brown, Ben, Salberg, Armorel, Boyer, Naomi, Pristopan, Veronika, Maynard, Victoria, Walker, Rachel, Hormis, Anil, Collier, Dawn, Graham, Cheryl, McCormick, Jake, Warrington, Jake, Cosgrove, Denise, McFarland, Denise, Ratcliffe, Judith, Charnock, Rob, Wynter, Inez, Gill, Mandy, Kirk, Jill, Paul, Paul, Ratnam, Valli, Shelton, Sarah, Jardine, Catherine, Hay, Alasdair, Williams, Dewi, Durga, Latha, Hibbert, Meg, Kennard-Holden, Gareth, Woodford, Chrsitopher, Tetla, Dariusz, Price, Alicia, Thomas, Alice, Thorpe, Chris, Knights, Ellen, Ward, Donna, Laha, Shondipon, Verlander, Mark, Williams, Alexandra, Prout, Rachel, Langton, Helen, Watters, Malcolm, Hunt, Charlotte, Novis, Catherine, Arif, Sarwat, Cunningham, Amy, Hewitt, Claire, Hindale, Julia, Jackson-Lawrence, Karen, Shepardson, Sarah, Wills, Maryanne, Butler, Susie, Tavares, Silivia, Barber, Russell, Hilldrith, Annette, Hubbard, Kelly, Egginton, Dawn, Clark, Michele, Purvis, Sarah, Sinclair, Simon, Collins, Vicky, Landeg, Bethan, Sell, Craig, Coetzee, Samantha, Gales, Alistair, Otahal, Igor, Icke, Becky, Raj, Meena, Williams, Caroline, Williams, Jill, Hill, Lucy, Kayani, Abdul, Masunda, Bridgett, Gondo, Prisca, Atayeva, Nigara, Cruz, Carina, Pattison, Natalie, Burnett, Caroline, Hatton, Jonathan, Heeney, Elaine, Newton, Maria, Al-Moasseb, Hassan, Behan, Teresa, Player, Jasmine, Stead, Rachael, Mitra, Atideb, Nauyokas, Kirsty, Humphreys, Sally, Cockerill, Helen, Tampsett, Ruth, Postovalova, Evgeniya, Coventry, Tina, McGregor, Amanda, Fowler, Susan, Macmahon, Mike, Cochrane, Patricia, Pirie, Sandra, Hanley, Sarah, Ali, Asifa, Brady, Megan, Dale, Sam, Dance, Annalisa, Gledhill, Lisa, Greig, Jill, Hanson, Kathryn, Holdroyd, Kelly, Home, Marie, Ishaq, Tahira, Kelly, Diane, Matapure, Lear, Melia, Deborah, Mellor, Samantha, Merwaha, Ekta, Nortcliffe, Tonicha, Shaw, Lisa, Shaw, Ryan, Wood, Tracy, Bayo, Lee-Ann, Usher, Miranda, Wilson, Alison, Kitson, Ross, Pinnell, Jez, Robinson, Matthew, Boltwood, Kaitlin, Birch, Jenny, Bough, Laura, Tutton, Rebecca, Winter-Goodwin, Barbara, Goodsell, Josie, Taylor, Kate, Williams, Patricia, Williams, Sarah, Cave, Ashleigh, Rees, James, Imeson-Wood, Janet, Smith, Jacqueline, Amin, Vishal, Karthik, Komala, Kausar, Rizwana, Anastasescu, Elena, Reid, Karen, Anumakonda, Vikram, Stoddart, Ella, Demetriou, Carrie, Eckbad, Charlotte, Howie, Lucy, Mitchard, Sarah, Ramos, Lidia, White, Katie, Hierons, Sarah, Kelly, Fiona, Serrano-Ruiz, Alfredo, Evans, Gabrielle, Nicol, Liz, Wilkins, Joy, Hulacka, Kim, Debreceni, Gabor, Brown, Alison, Crickmore, Vikki, Hill, Kay, Kannan, Thogulava, Dagutao, Zenaida, Beesley, Kate, Lewis, Alison, Perry, Jess, Antony, Sherly, Board, Sarah, Buckley, Clare, Pippard, Lucy, Tanate, Alfonso, Wood, Diane, Kubisz-Pudelko, Agnieska, Gouda, Ayman, Auld, Fiona, Donnachie, Joanne, Murdoch, Euan, Prentice, Lynn, Runciman, Nikole, Senaratne, Dhaneesha, Short, Abigail, Sweeney, Laura, Symon, Lesley, Todd, Anne, Turner, Patricia, McCann, Erin, Salutous, Dario, Edmond, Ian, Whitelaw, Lesley, Bland, Yvonne, Kajtor, Istvan, Kavanagh, Lisa, Singler, Karen, Linfield-Brown, George, Moore, Luke Stephen Prockter, Vizcaychipi, Marcela, Martins, Laura, Moore, Luke, Bull, Rhian, Carungcong, Jaime, Allen, Louise, Beranova, Eva, Knight, Alicia, Price, Carly, Tilbey, Sorrell, Turney, Sharon, Hazelton, Tracy, Tutt, Gabriella, Arora, Mansi, Turki, Salah, Sinfield, Emily, Deery, Joanne, Ramos, Hazel, Cristiano, Daniele, Dormand, Natalie, Farzad, Zohreh, Gummadi, Mahitha, Salmi, Sara, Sloane, Geraldine, Varghese, Mathew, Thwaites, Vicky, Patel, Brijesh, Kamal, Liyanage, Zborowski, Anelise Catelan, Coe, Ryan, Anderson, Madeleine, Beadle, Jane, Coates, Charlotte, Collins, Katy, Crowley, Maria, Johnson, Laura, King, Laura, Paramsothy, Remi, Sargeant, Janet, Silva, Pedro, Stuart, Carmel, Taylor, June, Tyl, David, Wakefield, Phillipa, Kamundi, Charlotte, Olufuwa, Olumide, Belagodu, Zakaulla, Gherman, Anca, Oakley, Naomi, Allan, John, Geary, Tim, Meikle, Alistair, O’Brien, Peter, Wood, Stephen, Clark, Andrew, Houston, Gordon, Black, Karen, Clarkson, Michelle, D’Sylva, Stuart, Morrison, Alan, Norman, Kathryn, Taylor, Margaret, Clements, Suzanne, Cohrane, Catriona, Gonzalez, Nora, Strachan, Dominic, Beith, Claire, Moar, Kirsten, Anderson, Peter, Archer, Katie, Burtenshaw, Andrew, Clayton, Sarah, Cother, Naiara, Cowley, Nicholas, Davis, Caroline, Digby, Stephen, Durie, Alison, Harrison, Alison, Low, Emma, McAlindon, Michael, McCurdy, Alex, Morgan, Aled, Rankin, Tobias, Thrush, Jessica, Tranter, Helen, Vigurs, Charlie, Wild, Laura, Murphy, Lorna, Smythe, Michelle, Brickell, Kathy, Ali, Inthakab Ali Mohamed, Beaumont, Karen, Elsaadany, Mohamed, Fernandes, Kay, Ally, Sameena Mohamed, Rangarajan, Harini, Sarathy, Varun, Selvanayagam, Sivarupan, Vedage, Dave, White, Matthew, Coton, Zoe, Joshy, Aricsa, Blunt, Mark, Curgenven, Hollie, Botfield, Liam, Dexter, Catherine, Kuravi, Aditya, Butler, Joanne, Chadwick, Robert, Ranga, Poonam, Richardson, Lisa, Virgilio, Emma, Anwer, Maddiha, Garg, Atul, Botfield, Donna, Marriott, Xana, Stewart, Keely, Mullan, Dee, Gaylard, Jane, Nowak, Justyna, Jones, Sian, Crawley, Rikki, Crew, Abigail, Cunningham, Mishell, Daniels, Allison, Harrison, Laura, Hope, Susan, Lancaster, Nicola, Matthews, Jamie, Wray, Gemma, Inweregbu, Ken, Cutts, Sarah, Miller, Katharine, Brady, Ailbhe, Chan, Rebekah, McIvor, Shane, Prady, Helena, Mathew, Bijoy, Little, Jeff, Furniss, Tim, Wright, Chris, King, Bernadette, Wasson, Christopher, O’Neill, Aisling, Turley, Christine, McGuigan, Peter, Collins, Erin, Finn, Stephanie, Green, Jackie, McAuley, Julie, Nair, Abitha, Quinn, Charlotte, Tauro, Suzanne, Ward, Kathryn, McGinlay, Michael, Reddy, Kiran, Ahmad, Norfaizan, Anderson, Samantha, Barker, Joann, Bauchmuller, Kris, Birchall, Kathryn, Bird, Sarah, Cawthron, Kay, Chetam, Luke, Cole, Joby, Donne, Ben, Foote, David, Ford, Amber, Hanratty, Helena, Harrington, Kate, Hesseldon, Lisa, Housley, Kay, Jackson, Yvonne, Jarman, Claire, Kibutu, Faith, Lenagh, Becky, Macharia, Irene, Masuko, Shamiso, Milner, Leanne, Newell, Helen, Nwafor, Lorenza, Oxspring, Simon, Phillips, Patrick, Raithatha, Ajay, Rowland-Jones, Sarah, Smith, Jacqui, Thompson, Roger, Trower, Helen, Walker, Sara, Watson, James, Wiles, Matthew, Lye, Alison, Willson, Jayne, Mills, Gary, Harris, Sansha, Hartill, Eleanor, Barron, Anthony, Collins, Ciara, Kaul, Sundeep, Nolan, Claire, Polgar, Oliver, Prendergast, Claire, Rogers, Paula, Shokkar, Rajvinder, Woodruff, Meriel, Mahay, Kanta, Reed, Anna, Meyrick, Hayley, Passmore, Heather, Farwell, James, O’Connell, Susan, Gregory, Jane, Barberis, Luigi, Harper, Rosemary, Smith, Tim, Armstrong, Diane, Bowey, Angie, Cowley, Anne, Corner, Andrew, Highgate, Judith, Rutherfurd, Claire, Taylor, Jo-Anne, Goodwin, Sarah, Eapen, Beena, Trim, Fiona, Donnison, Phil, Armstrong, Lisa, Bates, Hayley, Dooks, Emma, Farquhar, Fiona, Kitching, Amy, McParland, Chantal, Packham, Sophie, Hairsine, Brigid, Andreou, Premetie, Hales, Dawn, Mathews, Megha, Patel, Rekha, Barry, Peter, Flint, Neil, Hailstone, Jessica, Ghuman, Navneet, Leonard, Bethany, Lees, Rachel, Butcher, Deborah, Leng, Katy, Butterworth-Cowin, Nicola, O’Sullivan, Susie, Ghosh, Alison, Williams, Emma, Adams, Colene, Agasou, Anita, Arden, Tracie, Beekes, Mandy, Bowes, Amy, Boyle, Pauline, Button, Heather, Carnahan, Mandy, Carter, Anne, Childs, Danielle, Hurford, Fran, Hussain, Yasmin, Javaid, Ayesha, Jones, James, Leigh, Michael, Martin, Terry, Millward, Helen, Motherwell, Nichola, Newman, Julie, Rikunenko, Rachel, Stickley, Jo, Summers, Julie, Ting, Louise, Tivenan, Helen, Donaldson, Denise, Capps, Nigel, Cale, Emily, Jose, Sanal, Osbourne, Wendy, Pajak, Susie, Rankin, Jayne, Tonks, Louise, Baird, Tracy, Harkins, Margaret, Ruddy, Jim, West, Joe, Duffield, Joseph, Mallon, Lewis, Smith, Oliver, Smuts, Sara, Campbell, Andy, Davies, Cate, Davies, Sarah, Hughes, Rachel, Jobes, Lisa, Whitehead, Victoria, Watkins, Clare, Bowman, Fiona, Milligan, Barry, McPherson, Liane, Metherell, Stella, Harris, Nichola, Lake, Victoria, Radford, Elizabeth, Smallwood, Andy, Gopal, Shameer, Vassell, Katherine, Bell, Dina, Boyle, Rosalind, Douglas, Katie, Glass, Lynn, Lennon, Liz, Rattray, Austin, Lee, Emma, Jones, Danielle, Parsons, Penny, Attwood, Ben, Jefferson, Paul, Ranganathan, Mohan, Atwal, Inderjit, Campbell, Bridget, Day, Angela, Stagg, Camilla, Haynes, Emma, Ahmed, Cecilia, Clamp, Sarah, Colley, Julie, Haq, Risna, Hayes, Anne, Joseph, Sibet, Maqsood, Zahira, Hussain, Samia, Hulme, Jonathan, Domingos, Patience, Kumar, Rita, Purewal, Manjit, Taylor, Becky, Bunni, Lara, Latif, Monica, Jennings, Claire, Jose, Shilu, Marshall, Rebecca, Metryka, Aleksandra, Subramanian, Gayathri, Burgoyne, Adam, Tyler, Amanda, Waldron, Joanne, Hilltout, Paula, Evitts, Jayne, Ward, Geraldine, Bremmer, Pamela, Hawkins, Carl, Jackman, Sophie, Ogorek, Michal, Ashby, Kylie, Thornton, Lorraine, Mercer, Pauline, Halkes, Matthew, Revill, Adam, Saint, Bryony, Fletcher, Jo, Netherton, Kimberley, Chablani, Manish, Kirkby, Amy, Roper, Amanda, Szymiczek, Kinga, Sutherland, Isobel, O’Brien, Linda, Connell, Joanne, Davies, Kim, Lewis, Tracy, Omar, Zohra, Perkins, Emma, Sathe, Sonia, Davies, Ellie, Lyon, Alex, Mapfunde, Isheunesu, Willis, Charlotte, Hitchcock, Rachael, Hall, Kathryn, King, Christopher, Fagan, Andrew, Nazari, Roonak, Worsley, Lucy, Allibone, Suzanne, Kasipandian, Vidya, Patel, Amit, Cutting, Parisa, Genetu, Roman, Mac, Ainhi, Murphy, Anthony, Ward, Sinead, Butt, Fatima, Ayers, Amanda, Harrison, Wendy, Mackintosh, Katherine, North, Julie, Ashton, Lydia, Bi, Rehana, Owen, Samantha, Winmill, Helen, Scholefield, Barney, Blowing, Hannah, Williams, Erin, Duskova, Michaela, Edwards, Michelle, Rees, Alun, Thomas, Helen, Brooks, Jolene, Phipps, Janet, Brooks, Suzanne, Dennis, Catherine, Parris, Vicki, Srikaran, Sinduya, Sukha, Anisha, McGregor, Alistair, Tiongson, Gerlynn, Adams, Katie, Andrew, Benedict, Brayne, Adam, Carter, Sasha, Findlay, Louise, Fisher, Emma, Jackson, Peter, Kaye, Duncan, Parkin, Juliet, Tuckey, Victoria, Hunt, Jane, Love, Nicholas, van Koutrick, Lynne, Hanson, Ashley, Dent, Kathy, Horsley, Elizabeth, Pearson, Sandra, Spencer, Sue, Hutchinson, Dorothy, Potoczna, Dorota, Akhtar, Muhammad Nauman, Cottam, Lisa-Jayne, Sanders, Jack, Garcia, Sara Mingo, pakou, Glykeria, Filipe, Helder, Maharajh, Amitaa, de Neef, Mark, Martin, Daniel, Eastgate, Christine, Teoh, Poh Choo, Barrett, Fiona, Bradley, Clare, Donaldson, Avril, Mascarenhas, Mairi, O’Hara, Marianne, Okeefe, Laura, Clarke, Noreen, Whiteside, Jonathan, Campbell, Rachael, Matheson, Joanna, McDonald, Deborah, Patience, Donna, Rice, Polly, Clapham, Melanie, Mutch, Rachel, Craig, Hannah, Poultney, Una, Burns, Karen, Twiss, Sophie, Barton, Janet, George, Linsha, Harrop, Clare, Mathew, Sherly, Wright, David Justin, Harrison, Rachel, Toohie, Jordan, Chandler, Ben, Turnbull, Alison, Mallinson, Janine, Elliott, Kerry, Wolf-Roberts, Rebecca, Tench, Helen, Hobrok, Maria, Loosley, Ronda, McGuinness, Heather, Sims, Tanya, Afolabi, Deborah, Allison, Kathryn Sian, Anderson, Taya, Dore, Rachael, Jones, Dawn, Rogers, Naomi, Saunderson, Paula, Whitbread, Jennifer, O’Malley, Laura, Rad, Laura, Hawcutt, Daniel, Aldridge, Jonathan, Tolson, Melanie, Garrioch, Sweyn, Tomlinson, Joanne, Grosdenier, Michael, Loader, David, Kapoor, Ritoo, Hector, Gemma, Scherewode, Joslan, Sri-Chandana, Chunda, Stephenson, Lorraine, Marsh, Sarah, Rosa, Arnold Dela, Jhanji, Shaman, Bemand, Thomas, Howle, Ryan, Baikady, Ravishankar Rao, Thomas, Benjamin, Black, Ethel, Tatham, Kate, Gurram, Sambasivarao, Watson, Ekaterina, Quaid, Sheena, Saunderson, Anne, O’Brien, Rachel, Moultrie, Sam, Service, Jen, Cheyne, Clare, Odam, Miranda, Wiliams, Alison, Barnes, Nicky, Csabi, Peter, Rocha, Joana Da, Glynou, Louika, Huffenberger, Amy, Bryant, Jade, Pickard, Amy, Roe, Nicholas, Bellini, Arianna, Mayer, Anton, Burrow, Amy, Colley, Natalie, Evans, Jayne, Howlett, Alex, Khalifeh, Zeinab, Pryce, Jerldine, Gorman, Claire, Brady, Rebecca, Timlick, Elizabeth, Antoine, Pierre, Gupta, Abhinhav, Hardy, John, Houlden, Henry, Moncur, Eleanor, Tucci, Arianna, Tariq, Ambreen, Tagliavini, Emma, Ramsay, Becky, Fidler, Katy, Donnelly, Kevin, Hollis, Rebecca, Barr, Jocelyn, Boyd, Elizabeth, Irvine, Val, Shelley, Ben, Buckley, Julie, Hamilton, Charlene, Valdeavella, Kathryn, Bircham, Sarah, Liggett, Steven, Patil, Anand, Siddiq, Afshan, Goddard, Peter, Donovan, Sally, Zainy, Tala, Maleady-Crowe, Fiona, Todd, Linda, Salehi, Shahla, Elgar, Greg, Chan, Georgia, Arumugam, Prabhu, Patch, Christine, Rendon, Augusto, Bentley, David, Kingsley, Clare, Fowler, Tom A., Elliott, Paul, Tenesa, Albert, Aitkin, Emma, Aravindan, Latha, Armstrong, Ruth, Biggs, Heather, Boz, Ceilia, Brown, Adam, Chikowore, Primmy, Coutts, Audrey, Coyle, Judy, Cullum, Louise, Das, Sukamal, Day, Nicky, Donnelly, Lorna, Duncan, Esther, Finernan, Paul, Fourman, Max Head, Furlong, Anita, Furniss, James, Gallagher, Bernadette, Gilchrist, Tammy, Golightly, Ailsa, Hafezi, Katarzyna, Hamilton, Debbie, Hendry, Ross, Kearns, Naomi, Law, Dawn, Law, Rachel, Law, Sarah, Lidstone-Scott, Rebecca, Lauder, Christen, Macgillivray, Louise, Maclean, Alan, Mal, Hanning, McCafferty, Sarah, Mcmaster, Ellie, Meikle, Jen, Moore, Shona C., Murphy, Sheena, Mybaya, Hellen, Oosthuyzen, Wilna, Zheng, Chenqing, Chen, Jiantao, Paterson, Trevor, Tucker, Petra, Schon, Katherine, Stenhouse, Andrew, Das, Mihaela, Swets, Maaike, Szoor-McElhinney, Helen, Taneski, Filip, Turtle, Lance, Wackett, Tony, Ward, Mairi, Weaver, Jane, Wrobel, Nicola, Rakitko, Alexander, Ilinsky, Valery, Yermakovich, Danat, Popov, Iaroslav, Chernitsov, Alexander, Kovalenko, Elena, Vergasova, Ekaterina, Prokhorov, Alexandr, Krasnenko, Anna, Plotnikov, Nikolay, Stetsenko, Ivan, Kim, Anna, Cirulli, Elizabeth T., Schiabor Barrett, Kelly M., Bolze, Alexandre, White, Simon, Washington, Nicole L., Lu, James T., Riffle, Stephen, Tanudjaja, Francisco, Wang, Xueqing, Ramirez, Jimmy M., Leonetti, Nicole, Sandoval, Efren, Neveux, Iva, Dabe, Shaun, Grzymski, Joseph J., Joshi, Madhvi N., Dixit, Raghav D., Shah, Pranay K., Upadhyay, Kamlesh J., Chuhan, Naresh T., Desai, Kairavi J., Shah, Meenakshi R., Modi, Bhavesh, Joshi, Chaitanya G., Pandit, Ramesh J., Singh, Indra, Ansari, Afzal I., Raval, Janvi N., Patel, Zarna Z., Moreno-Estrada, Andres, Vázquez-Pérez, Joel Armando, Castillejos-López, Manuel, Aquino-Gálvez, Arnoldo, Shamah-Levy, Teresa, Ávila-Arcos, María C., Luna, María Teresa Tusié, Hidalgo-Miranda, Alfredo, Barberena-Jonas, Carmina, Quinto-Cortés, Consuelo D., Ávila-Arcos, Marco Antonio, Huerta-Chagoya, Alicia, García-García, Lourdes, Barnetche, Jesús Martinez, Alpuche-Aranda, Celia, Rivera, Juan A., Gutiérrez, Tonatiuh Barrientos, Ochoa-Guzmán, Ana, Ordoñez-Sánchez, Maria Luisa, Segura-Kato, Yayoi, Herrera-Montalvo, Luis Alonso, Mendoza-Vargas, Alfredo, Reyes-Grajeda, Juan Pablo, Cruz-Cruz, Alonso D., Velázquez-Cruz, Rafael, Torres-Espíndola, Luz María, Sierra-Vargas, Martha Patricia, Camarena, Angel, Ruiz, Víctor, Chávez-Alderete, Jaime, Jaime-Capetillo, María Esther, Guadarrama-Pérez, Cristóbal, Zúñiga-Ramos, Joaquin, Olivera-Ramírez, Alejandra, Martínez, Miguel Angel López, Serna-Muñoz, Ricardo, Garmendia, Adriana, Namkoong, Ho, Okada, Yukinori, Imoto, Seiya, Katayama, Kazuhiko, Fukunaga, Koichi, Kitagawa, Yuko, Sato, Toshiro, Hasegawa, Naoki, Kumanogoh, Atsushi, Kimura, Akinori, Ai, Masumi, Tokunaga, Katsushi, Kanai, Takanori, Miyano, Satoru, Ogawa, Seishi, Edahiro, Ryuya, Sonehara, Kyuto, Shirai, Yuya, Ishii, Makoto, Kabata, Hiroki, Masaki, Katsunori, Kamata, Hirofumi, Ikemura, Shinnosuke, Chubachi, Shotaro, Okamori, Satoshi, Terai, Hideki, Tanaka, Hiromu, Morita, Atsuho, Lee, Ho, Asakura, Takanori, Sasaki, Junichi, Morisaki, Hiroshi, Uwamino, Yoshifumi, Nanki, Kosaku, Mikami, Yohei, Tomono, Kazunori, Kato, Kazuto, Matsuda, Fumihiko, Takahashi, Meiko, Hizawa, Nobuyuki, Takeda, Yoshito, Hirata, Haruhiko, Shiroyama, Takayuki, Miyawaki, Satoru, Suzuki, Ken, Maeda, Yuichi, Nii, Takuro, Noda, Yoshimi, Niitsu, Takayuki, Adachi, Yuichi, Enomoto, Takatoshi, Amiya, Saori, Hara, Reina, Takahashi, Kunihiko, Anzai, Tatsuhiko, Hasegawa, Takanori, Ito, Satoshi, Koike, Ryuji, Endo, Akifumi, Uchimura, Yuji, Miyazaki, Yasunari, Honda, Takayuki, Tateishi, Tomoya, Tohda, Shuji, Ichimura, Naoya, Sonobe, Kazunari, Sassa, Chihiro, Nakajima, Jun, Nannya, Yasuhito, Omae, Yosuke, Takahashi, Kazuhisa, Harada, Norihiro, Hiki, Makoto, Takagi, Haruhi, Nakamura, Ai, Tagaya, Etsuko, Kawana, Masatoshi, Arimura, Ken, Ishiguro, Takashi, Takayanagi, Noboru, Isono, Taisuke, Takaku, Yotaro, Takano, Kenji, Anan, Ryusuke, Nakajima, Yukiko, Nakano, Yasushi, Nishio, Kazumi, Ueda, Soichiro, Hayashi, Reina, Tateno, Hiroki, Hase, Isano, Yoshida, Shuichi, Suzuki, Shoji, Mitamura, Keiko, Saito, Fumitake, Ueda, Tetsuya, Azuma, Masanori, Nagasaki, Tadao, Yasui, Yoshinori, Hasegawa, Yoshinori, Mutoh, Yoshikazu, Yoshiyama, Takashi, Shoko, Tomohisa, Kojima, Mitsuaki, Adachi, Tomohiro, Ishikawa, Motonao, Takahashi, Kenichiro, Watanabe, Kazuyoshi, Manabe, Tadashi, Ito, Fumimaro, Fukui, Takahiro, Funatsu, Yohei, Koh, Hidefumi, Hirai, Yoshihiro, Kawashima, Hidetoshi, Narita, Atsuya, Niwa, Kazuki, Sekikawa, Yoshiyuki, Saito, Fukuki, Yoshiya, Kazuhisa, Yoshihara, Tomoyuki, Suzuki, Yusuke, Nakayama, Sohei, Masuzawa, Keita, Nishi, Koichi, Nishitsuji, Masaru, Tani, Maiko, Inoue, Takashi, Hirano, Toshiyuki, Kobayashi, Keigo, Miyazawa, Naoki, Kimura, Yasuhiro, Sado, Reiko, Ogura, Takashi, Kitamura, Hideya, Murohashi, Kota, Nakachi, Ichiro, Baba, Rie, Arai, Daisuke, Fuke, Satoshi, Saito, Hiroshi, Kuwahara, Naota, Fujiwara, Akiko, Okada, Takenori, Baba, Tomoya, Noda, Junya, Mashimo, Shuko, Yagi, Kazuma, Shiomi, Tetsuya, Hashiguchi, Mizuha, Odani, Toshio, Mochimaru, Takao, Oyamada, Yoshitaka, Mori, Nobuaki, Izumi, Namiki, Nagata, Kaoru, Taki, Reiko, Murakami, Koji, Yamada, Mitsuhiro, Sugiura, Hisatoshi, Hayashi, Kentaro, Shimizu, Tetsuo, Gon, Yasuhiro, Fujitani, Shigeki, Tsuchida, Tomoya, Yoshida, Toru, Kagaya, Takashi, Kita, Toshiyuki, Sakagami, Satoru, Kimizuka, Yoshifumi, Kawana, Akihiko, Nakamura, Yoshihiko, Ishikura, Hiroyasu, Takata, Tohru, Kikuchi, Takahide, Taniyama, Daisuke, Nakamura, Morio, Kodama, Nobuhiro, Kaneyama, Yasunari, Maeda, Shunsuke, Nagasaki, Yoji, Okamoto, Masaki, Ishihara, Sayoko, Ito, Akihiro, Chihara, Yusuke, Takeuchi, Mayumi, Onoi, Keisuke, Hashimoto, Naozumi, Wakahara, Keiko, Ando, Akira, Masuda, Makoto, Wakabayashi, Aya, Watanabe, Hiroki, Sageshima, Hisako, Nakada, Taka-Aki, Abe, Ryuzo, Shimada, Tadanaga, Kawamura, Kodai, Ichikado, Kazuya, Nishiyama, Kenta, Yamasaki, Masaki, Hashimoto, Satoru, Kusaka, Yu, Ohba, Takehiko, Isogai, Susumu, Takada, Minoru, Kanda, Hidenori, Komase, Yuko, Sano, Fumiaki, Asano, Koichiro, Oguma, Tsuyoshi, Harada, Masahiro, Takahashi, Takeshi, Shibusawa, Takayuki, Abe, Shinji, Kono, Yuta, Togashi, Yuki, Izumo, Takehiro, Inomata, Minoru, Awano, Nobuyasu, Ogawa, Shinichi, Ogata, Tomouki, Ishihara, Shoichiro, Kanehiro, Arihiko, Ozaki, Shinji, Fuchimoto, Yasuko, Kitagawa, Yuichiro, Yoshida, Shozo, Ogura, Shinji, Nishiyama, Kei, Yoshida, Kousuke, Beppu, Satoru, Fukuyama, Satoru, Eriguchi, Yoshihiro, Yonekawa, Akiko, Inoue, Yoshiaki, Yamagata, Kunihiro, Chiba, Shigeru, Narumoto, Osamu, Nagai, Hideaki, Ooshima, Nobuharu, Motegi, Mitsuru, Sagara, Hironori, Tanaka, Akihiko, Ohta, Shin, Shibata, Yoko, Tanino, Yoshinori, Sato, Yuki, Yamada, Yuichiro, Hashino, Takuya, Shinoki, Masato, Iwagoe, Hajime, Imamura, Tomonori, Umeda, Akira, Shimada, Hisato, Endo, Mayu, Hayashi, Shinichi, Takahashi, Mai, Nakano, Shigefumi, Yatomi, Masakiyo, Maeno, Toshitaka, Ishii, Tomoo, Utsugi, Mitsuyoshi, Ono, Akihiro, Kanaoka, Kensuke, Ihara, Shoichi, Komuta, Kiyoshi, Nishida, Nao, Kawai, Yosuke, Sugiyama, Masaya, Alawneh, Laith M., Maswadeh, Kinda B., Alsoub, Fatima S., AlRawashdeh, Tala J., Esawi, Ezaldeen, Abu Alragheb, Bayan O., Maswadeh, Ahmad B., Al-Kadash, Abdulfattah, Al-Ani, Abdallah, Alsafadi, Dana B., Shahin, Mohammad A., Qtaish, Nuseibah Al, Alawneh, Fade M., Abulail, Joseph A., Zhlawi, Hadi J., Alhousani, Tasneem N., Alzuraiqi, Mohammad R., Al-Ja’afreh, Mohammad M., Allouzy, Sara K., ALjalamdeh, Mothafer, Mansour, Tareq M., Alamer, Lina M., Issa, Ali Banni, Bani younis, Fatima M., Hawari, Feras I., Hayajneh, Wail A., Obeidat, Nathir M., Ahram, Mamoun, Zhlawi, Moh’d Wahib J., Alshaer, Walhan, Al-Kasasbeh, Malak M., Naffa, Randa G., Ismail, Mohammad A., Abdullah, Mohammed S., Ismail, Said I., Obeidat, Ma’en, Hernández Cordero, Ana I., Sin, Don D., Bossé, Yohan, Joubert, Philippe, Hao, Ke, Nickle, David, Timens, Wim, van den Berge, Maarten, Feng, Yen-Chen Anne, Mercader, Josep, Weiss, Scott T., Karlson, Elizabeth W., Smoller, Jordan W., Murphy, Shawn N., Meigs, James B., Woolley, Ann E., Green, Robert C., Mandla, Ravi, Schroeder, Philip, Perez, Emma F., Lee, Seung Hyuk T., Flores-Silva, Fernando Daniel, Chiquete, Erwin, Cantú-Brito, Carlos, Sifuentes-Osornio, José, de León-Garduño, Alfredo Ponce, Román-Montes, Carla Marina, Chávez-Manzanera, Emma, Velasco, Donaji Gómez, Martagón-Rosado, Alexandro, Cruz-Bautista, Ivette, Gómez-Pérez, Francisco Javier, Díaz-Olavarrieta, Claudia, Valdés, Paloma Almeda, Muñóz-Hernández, Linda Liliana, Mehta, Roopa Pravin, Elías-López, Daniel, Tusié-Luna, Teresa, Pajukanta, Päivi, Sukhatme, Mihir G., Moreno-Macías, Hortensia, Ruth, Johnson, González-Behn-Eschenburg, Sebastián, García-Grimshaw, Miguel, Guillen-Pineda, Luz Elizabeth, de los Ángeles Vargas-Martínez, María, Rodríguez, Maribel, Rodríguez-Guillén, Rosario, Ordoñez, María Luisa, Rajme-López, Sandra, González-Lara, María Fernanda, Luna-Moreno, Dalia, de Jesús Suárez López, Jannet, Guillén-Quintero, Daniela Mariel, Vega, Juan, Duran-Coyote, Salvador, Guerra-García, María Teresa, Durán-Gómez, Michelle, Vigueras-Hernández, Alma, Ramírez-Jiménez, Marco Eduardo, Grajeda-González, Samara Lissete, Ramos-Galicia, Enrique Manuel, Ramírez-Carrillo, Martha Fernanda, Fernandez-Ruiz, Juan, Chirino-Pérez, Amanda, Romero-Molina, Ángel Omar, Zavaleta, David Alejandro Fuentes, Jaramillo, María Andrea Mac Donald, López, Katia Jarely Prieto, Incontri-Abraham, Diego, Rosado, Wendy Natalia, Catalán, María Alonso, Aguilar, Sonia Evelyn Vital, Zamudio, Ileana Paola Montero, Ruíz-Ruíz, Eduardo, de Jesús Carrera García, Kevin, Guerrero, Cristina Villarreal, Martínez, Ana Isabel Rodríguez, Moscoso-Sánchez, Rogelio, del Consuelo Rodríguez Mancilla, María, Villa, Antonio, Luna-Ramírez, Samuel Alejandro, Hernández-Hernández, Sergio, Frias, Erika, Campos, Alejandro, Morales-Sosa, Paola Alessandra, Toxqui-Merchant, Luis Enrique, García, Karla, Pasaniuc, Bogdan, Butte, Manish J., Geschwind, Daniel H., Aguilar-Salinas, Carlos A., Heidecker, Bettina, Kurth, Florian, Sander, Leif E., Skurk, Carsten, Landmesser, Ulf, Karadeniz, Zehra, Wang, Xiaomin, Poller, Wolfgang, Suwalski, Phillip, Ripke, Stephan, Braun, Alice, Kraft, Julia, Mayer, Alena, Lippert, Lena J., Helbig, Elisa T., Thibeault, Charlotte, Awasthi, Swapnil, Mbarek, Hamdi, Saad, Chadi, Al-Sarraj, Yaser, Badji, Radja Messai, Al-Muftah, Wadha, Thani, Asma Al, Afifi, Nahla, Sadiq, Fouzia, Khan, Mohammad I., Bhutta, Muhammad J., Khan, Hania, Khan, Madeeha, Ain, Quratul, Junaid, Ayesha, Khan, Ejaz A., Sypniewski, Mateusz, Lejman, Adrian, Zawadzki, Paweł, Sztromwasser, Paweł, Król, Zbigniew, Dobosz, Paula, Stojak, Joanna, Flores, Carlos, Carracedo, Ángel, Aguilar, Carlos, Arranz, María J., Baptista-Rosas, Raúl C., Bezerra, Joao F., Bezerra, Marcos A. C., Brugada, Ramón, Bustos, Matilde, Castano, Luis, Conde-Vicente, Rosa, Cordero-Lorenzana, M. Lourdes, De Martino-Rodríguez, Alba, Domínguez-Garrido, Elena, Fariñas, María Carmen, Gil-Fournier, Belén, Herrero, María José, Lattig, María Claudia, Martín-López, Caridad, Martín, Vicente, Martinez-Nieto, Oscar, Martinez-Lopez, Iciar, Mazzeu, Juliana F., Macías, Eleuterio Merayo, Cuerda, Victor Moreno, Silbiger, Vivian N., Oliveira, Silviene F., Parellada, Mara, Santos, Ney P. C., Pérez-Matute, Patricia, Perez, Patricia, Perucho, Teresa, Porras-Hurtado, Gloria L., Pujol, Aurora, Fernández-Rodríguez, Amanda, Jimenez-Sousa, María A., Rodríguez-Ruiz, Emilio, Rodriguez-Artalejo, Fernando, Rodriguez-Garcia, José A., Ruiz-Cabello, Francisco, Soria, José Manuel, Tamayo, Eduardo, Teper, Alejandro, Torres-Tobar, Lilian, Urioste, Miguel, Yáñez, Zuleima, Zarate, Ruth, Guillen-Navarro, Encarna, Ayuso, Carmen, González-Neira, Anna, Riancho, José A., Rojas-Martinez, Augusto, Lapunzina, Pablo, Cruz, Raquel, Diz-de Almeida, Silvia, Ceballos, Francisco C., Lorenzo-Salazar, José M., González-Montelongo, Rafaela, Quintela, Inés, Pita, Guillermo, Gago-Domínguez, Manuela, Porras, Marta Sevilla, Tenorio-Castaño, Jair Antonio, Nevado, Julian, Aguado, Jose María, Aguilera-Albesa, Sergio, Almadana, Virginia, Almoguera, Berta, Alvarez, Nuria, Andreu-Bernabeu, Álvaro, Arango, Celso, Artiga, Maria-Jesus, Barreda-Sánchez, María, Belhassen-Garcia, Moncef, Boix-Palop, Lucía, Brion, María, Carbonell, Cristina, Castelao, Jose E., Cortes-Sanchez, Jose L., Corton, Marta, Darnaude, M. Teresa, del Campo-Pérez, Victor, de Bustamante, Aranzazu Diaz, Luchessi, Andre D., Eiros, Rocío, Sanabria, Gladys Mercedes Estigarribia, Fernández-Robelo, Uxía, Fernández-Villa, Tania, Gómez-Arrue, Javier, Álvarez, Beatriz González, de Quirós, Fernan Gonzalez Bernaldo, González-Peñas, Javier, Gutiérrez-Bautista, Juan F., Herrero-Gonzalez, Antonio, Borja, Anabel Liger, Lopez-Rodriguez, Rosario, Mancebo, Esther, Martinez-Resendez, Michel F., Martinez-Perez, Angel, Minguez, Pablo, Ortega-Paino, Eva, Paz-Artal, Estela, Pérez-Tomás, M. Elena, Pinsach-Abuin, Mel·lina, Pompa-Mera, Ericka N., León, Soraya Ramiro, Resino, Salvador, Fernandes, Marianne R., Ruiz-Hornillos, Javier, Ryan, Pablo, Souto, Juan Carlos, Tamayo-Velasco, Alvaro, Taracido-Fernandez, Juan Carlos, Valencia-Ramos, Juan, de Heredia, Miguel López, Pedersen, Ole B., Erikstrup, Christian, Ostrowski, Sisse R., Stefansson, Kari, Mikkelsen, Susan, Sørensen, Erik, Burgos, Celia, Andersen, Steffen, Brugdorf, Kristoffer, Hansen, Thomas F., Hjalgrim, Henrik, Jemec, Gregor B., Nyegaard, Mette, Werge, Thomas, Johansson, Pär I., Didriksen, Maria, Schwinn, Michael, Jacobsen, Rikke L., Hindhede, Lotte, Rostgaard, Klaus, Gudbjartsson, Daniel, Stefánsson, Hreinn, Þorsteinsdóttir, Unnur, Nielsen, Kaspar R., Bruun, Mie Topholm, Dinh, Khoa M., Larsen, Margit A. H., Sækmose, Susanne G., Zeberg, Hugo, Nkambul, Lindo, Frithiof, Robert, Hultström, Michael, Lipcsey, Miklos, Tardif, Nicolas, Rooyackers, Olav, Grip, Jonathan, Maricic, Tomislav, Heid, Iris M., Wagner, Ralf, Überla, Klaus, Winkler, Thomas W., Wiegrebe, Simon, Gorski, Mathias, Stark, Klaus J., Peterhoff, David, Einhauser, Sebastian, Niller, Hans-Helmut, Beileke, Stephanie, Johnson, Ruth, Freimer, Nelson, Ding, Yi, Chiu, Alec, Chang, Timothy S., Boutros, Paul, Karczewski, Konrad J., Martin, Alicia R., Wilson, Daniel J., Spencer, Chris C. A., Crook, Derrick W., Wyllie, David H., O’Connell, Anne Marie, Atkinson, Elizabeth G., Tsuo, Kristin, Baya, Nikolas, Turley, Patrick, Gupta, Rahul, Walters, Raymond K., Palmer, Duncan S., Sarma, Gopal, Solomonson, Matthew, Cheng, Nathan, Lu, Wenhan, Churchhouse, Claire, Goldstein, Jacqueline I., King, Daniel, Zhou, Wei, Seed, Cotton, Daly, Mark J., Finucane, Hilary, Bryant, Sam, Satterstrom, F. Kyle, Band, Gavin, Earle, Sarah G., Lin, Shang-Kuan, Arning, Nicolas, Koelling, Nils, Armstrong, Jacob, Rudkin, Justine K., Callier, Shawneequa, Cusick, Caroline, Fernandez-Cadenas, Israel, Planas, Anna M., Perez-Tur, Jordi, Llucià-Carol, Laia, Cullell, Natalia, Muiño, Elena, Cárcel-Márquez, Jara, DeDiego, Marta L., Iglesias, Lara Lloret, Soriano, Alex, Rico, Veronica, Agüero, Daiana, Bedini, Josep L., Lozano, Francisco, Domingo, Carlos, Robles, Veronica, Ruiz-Jaén, Francisca, Márquez, Leonardo, Gomez, Juan, Coto, Eliecer, Albaiceta, Guillermo M., García-Clemente, Marta, Dalmau, David, Arranz, Maria J., Dietl, Beatriz, Serra-Llovich, Alex, Soler-Palacin, Pere, Colobran, Roger, Martin-Nalda, Andrea, Parra-Martínez, Alba, Bernardo, David, Rojo, Silvia, Fiz-López, Aida, Arribas-Rodriguez, Elisa, Cal-Sabater, Paloma, Segura, Tomás, González-Villar, Esther, Serrano-Heras, Gemma, Martí-Fàbregas, Joan, Jiménez-Xarrié, Elena, de Felipe Mimbrera, Alicia, Masjuan, Jaime, García-Madrona, Sebastian, Domínguez-Mayoral, Anna, Villalonga, Joan Montaner, Menéndez-Valladares, Paloma, Kanai, M, Andrews, S, Cordioli, M, Stevens, C, Neale, B, Daly, M, Ganna, A, Pathak, G, Iwasaki, A, Karjalainen, J, Mehtonen, J, Pirinen, M, Chwialkowska, K, Trankiem, A, Balaconis, M, Veerapen, K, Wolford, B, Ahmad, H, von Hohenstaufen Puoti, K, Boer, C, Boua, P, Butler-Laporte, G, Cadilla, C, Chwiałkowska, K, Colombo, F, Douillard, V, Dueker, N, Dutta, A, El-Sherbiny, Y, Eltoukhy, M, Esmaeeli, S, Faucon, A, Fave, M, Cadenas, I, Francescatto, M, Francioli, L, Franke, L, Fuentes, M, Durán, R, Cabrero, D, Harry, E, Jansen, P, Szentpéteri, J, Kaja, E, Kirk, C, Kousathanas, A, Krieger, J, Patel, S, Lemaçon, A, Limou, S, Lió, P, Marouli, E, Marttila, M, Medina-Gómez, C, Michaeli, Y, Migeotte, I, Mondal, S, Moreno-Estrada, A, Moya, L, Nakanishi, T, Nasir, J, Pasko, D, Pearson, N, Pereira, A, Priest, J, Prijatelj, V, Prokić, I, Teumer, A, Várnai, R, Romero-Gómez, M, Roos, C, Rosenfeld, J, Ruolin, L, Schulte, E, Schurmann, C, Sedaghati-khayat, B, Shaheen, D, Shivanathan, I, Sipeky, C, Sirui, Z, Striano, P, Tanigawa, Y, Remesal, A, Vadgama, N, Vallerga, C, van der Laan, S, Verdugo, R, Wang, Q, Wei, Z, Zainulabid, U, Zárate, R, Auton, A, Shelton, J, Shastri, A, Weldon, C, Filshtein-Sonmez, T, Coker, D, Symons, A, Aslibekyan, S, O’Connell, J, Ye, C, Hatoum, A, Agrawal, A, Bogdan, R, Colbert, S, Thompson, W, Fan, C, Johnson, E, Niazyan, L, Davidyants, M, Arakelyan, A, Avetyan, D, Bekbossynova, M, Tauekelova, A, Tuleutayev, M, Sailybayeva, A, Ramankulov, Y, Zholdybayeva, E, Dzharmukhanov, J, Kassymbek, K, Tsechoeva, T, Turebayeva, G, Smagulova, Z, Muratov, T, Khamitov, S, Kwong, A, Timpson, N, Niemi, M, Rahmouni, S, Guntz, J, Beguin, Y, Pigazzini, S, Nkambule, L, Georges, M, Moutschen, M, Misset, B, Darcis, G, Gofflot, S, Bouysran, Y, Busson, A, Peyrassol, X, Wilkin, F, Pichon, B, Smits, G, Vandernoot, I, Goffard, J, Tiembe, N, Morrison, D, Afilalo, J, Mooser, V, Richards, J, Rousseau, S, Durand, M, Forgetta, V, Laurent, L, Afrasiabi, Z, Bouab, M, Tselios, C, Xue, X, Afilalo, M, Oliveira, M, St-Cyr, J, Boisclair, A, Ragoussis, J, Auld, D, Kaufmann, D, Lathrop, G, Bourque, G, Décary, S, Falcone, E, Montpetit, A, Piché, A, Renoux, C, Tremblay, K, Tse, S, Zawati, M, Davis, L, Cox, N, Below, J, Sealock, J, Shuey, M, Polikowsky, H, Petty, L, Shaw, D, Chen, H, Zhu, W, Schmidt, A, Ludwig, K, Maj, C, Rolker, S, Balla, D, Behzad, P, Nöthen, M, Fazaal, J, Keitel, V, Jensen, B, Feldt, T, Marx, N, Dreher, M, Pink, I, Cornberg, M, Illig, T, Lehmann, C, Schommers, P, Rybniker, J, Augustin, M, Knopp, L, Kurth, I, Eggermann, T, Volland, S, Berger, M, Brenner, T, Hinney, A, Witzke, O, Konik, M, Bals, R, Herr, C, Ludwig, N, Walter, J, Latz, E, Schmidt, S, Brooks, J, Bull, S, Elliott, L, Gagnon, F, Greenwood, C, Hung, R, Lawless, J, Paterson, A, Sun, L, Rauh, M, Briollais, L, Gingras, A, Bombard, Y, Pugh, T, Simpson, J, Goneau, L, Halevy, A, Maslove, D, Borgundvaag, B, Devine, L, 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C., Thompson, Wesley K., Fan, Chun Chieh, Johnson, Emma C., Niazyan, Lyudmila, Davidyants, Mher, Arakelyan, Arsen, Avetyan, Diana, Bekbossynova, Makhabbat, Tauekelova, Ainur, Tuleutayev, Mukhtar, Sailybayeva, Aliya, Ramankulov, Yerlan, Zholdybayeva, Elena, Dzharmukhanov, Jarkyn, Kassymbek, Kuat, Tsechoeva, Tatyana, Turebayeva, Gulsimzhan, Smagulova, Zauresh, Muratov, Timur, Khamitov, Sadyk, Kwong, Alex S. F., Timpson, Nicholas J., Niemi, Mari E. K., Rahmouni, Souad, Guntz, Julien, Beguin, Yves, Pigazzini, Sara, Nkambule, Lindokuhle, Georges, Michel, Moutschen, Michel, Misset, Benoit, Darcis, Gilles, Gofflot, Stéphanie, Bouysran, Youssef, Busson, Adeline, Peyrassol, Xavier, Wilkin, Françoise, Pichon, Bruno, Smits, Guillaume, Vandernoot, Isabelle, Goffard, Jean-Christophe, Tiembe, Nicky, Morrison, David R., Afilalo, Jonathan, Mooser, Vincent, Richards, J. 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Mark, Bourque, Guillaume, Décary, Simon, Falcone, Emilia Liana, Montpetit, Alexandre, Piché, Alain, Renoux, Christel, Tremblay, Karine, Tse, Sze Man, Zawati, Ma’n H., Davis, Lea K., Cox, Nancy J., Below, Jennifer E., Sealock, Julia M., Faucon, Annika B., Shuey, Megan M., Polikowsky, Hannah G., Petty, Lauren E., Shaw, Douglas M., Chen, Hung-Hsin, Zhu, Wanying, Schmidt, Axel, Ludwig, Kerstin U., Maj, Carlo, Rolker, Selina, Balla, Daniella, Behzad, Pari, Nöthen, Markus M., Fazaal, Julia, Keitel, Verena, Jensen, Björn-Erik Ole, Feldt, Torsten, Marx, Nikolaus, Dreher, Michael, Pink, Isabell, Cornberg, Markus, Illig, Thomas, Lehmann, Clara, Schommers, Philipp, Rybniker, Jan, Augustin, Max, Knopp, Lisa, Kurth, Ingo, Eggermann, Thomas, Volland, Sonja, Berger, Marc M., Brenner, Thorsten, Hinney, Anke, Witzke, Oliver, Konik, Margarethe J., Bals, Robert, Herr, Christian, Ludwig, Nicole, Walter, Jörn, Latz, Eicke, Schmidt, Susanne V., Brooks, Jennifer D., Bull, Shelley, Elliott, Lloyd T., Gagnon, France, Greenwood, Celia M. T., Hung, Rayjean J., Lawless, Jerry F., Paterson, Andrew D., Sun, Lei, Rauh, Michael, Briollais, Laurent, Gingras, Anne-Claude, Bombard, Yvonne, Pugh, Trevor J., Simpson, Jared, Goneau, Lee W., Halevy, Anat R., Maslove, David M., Borgundvaag, Bjug, Devine, Luke, Bearss, Erin, Richardson, David, Arnoldo, Saranya, Friedman, Steven Marc, Taher, Ahmed, Stern, Seth, Dagher, Marc, Vasilevska-Ristovska, Jovanka, Biggs, Catherine M., Mickiewicz, Beata, Strug, Lisa J., Scherer, Stephen W., Aziz, Naveed, Jones, Steven J. M., Knoppers, Bartha M., Lathrop, Mark, Turvey, Stuart E., Yeung, Rae S. M., Allen, Upton, Cheung, Angela M., Herridge, Margaret S., Hunt, Miranda, Lerner-Ellis, Jordan, Taher, Jennifer, Parekh, Rulan S., Hiraki, Linda T., Cowan, Juthaporn, Ducharme, Francine M., Ostrowski, Mario, Bernier, Francois P., Kellner, Jim, Garg, Elika, Yoo, Samantha, Vlasschaert, Caitlyn, Frangione, Erika, Chung, Monica, Noor, Abdul, Greenfeld, Elena, Colwill, Karen, Clausen, Marc, Chao, Gary, Yue, FengYun, Fritzler, Marvin, Whitney, Joseph, Thiruvahindrapuram, Bhooma, Garant, Jean-Michel, Abraham, Rohan, Davis, Adrienne, Campigotto, Aaron, Papenburg, Jesse, Niranjan, Kissoon, Betschel, Stephen, Sadarangani, Manish, Barton-Forbes, Michelle, Hanley, Michaela, Fung, Chun Yiu Jordan, Lapadula, Elisa, MacDonald, Georgia, Puopolo, Michael, Kaushik, Deepanjali, Nirmalanathan, Konika, Wong, Iris, Khan, Zeeshan, Zarei, Natasha, Michalowska, Maria, Modi, Bhavi P., Persia, Pourshahnazari, Estacio, Antonio, Buchholz, Megan, Cheatley, Patti Lou, Lorenti, Miranda, Aman, Nowrin F., Matveev, 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Tsourlos, Stavros, Athanasiou, Lazaros, Kolios, Nikolaos-Gavriil, Pappa, Christiana, Papathanasiou, Alexandros, Pargana, Eleni, Nasiou, Maria, Kosmidou, Maria, Rapti, Iro, Ntotsikas, Evangelos, Chaliasos, Konstantinos, Ntzani, Evangelia, Evangelou, Evangelos, Gartzonika, Konstantina, Georgiou, Ioannis, Tzoulaki, Ioanna, Ellinghaus, David, Degenhardt, Frauke, Cáceres, Mario, Juzenas, Simonas, Lenz, Tobias L., Albillos, Agustín, Julià, Antonio, Prati, Daniele, Solligård, Erik, Garcia, Federico, Tran, Florian, Hanses, Frank, Baselli, Guido, Zoller, Heinz, Holter, Jan Cato, Fernández, Javier, Barretina, Jordi, Valenti, Luca, Bujanda, Luis, Buti, Maria, D’Amato, Mauro, Banales, Jesus M., Rosenstiel, Philip, Koehler, Philipp, Invernizzi, Pietro, de Cid, Rafael, Asselta, Rosanna, Schreiber, Stefan, Duga, Stefano, Hehr, Ute, Franke, Andre, Maya-Miles, Douglas, Hov, Johannes R., Karlsen, Tom H., Folseraas, Trine, Teles, Ana, Tanck, Anja, Gassner, Christoph, Azuure, Clinton, Wacker, Eike Matthias, Uellendahl-Werth, Florian, Hemmrich-Stanisak, Georg, ElAbd, Hesham, Kässens, Jan, Arora, Jatin, Lerga-Jaso, Jon, Wienbrandt, Lars, Rühlemann, Malte Christoph, Wendorff, Mareike, Figuera Basso, Maria E., Vadla, May Sissel, Wittig, Michael, Braun, Nicole, Lenning, Ole Bernt, Özer, Onur, Myhre, Ronny, Raychaudhuri, Soumya, Wesse, Tanja, Albrecht, Wolfgang, Yi, Xiaoli, Ortiz, Aaron Blandino, de Salazar, Adolfo, Chercoles, Adolfo Garrido, Palom, Adriana, Ruiz, Agustín, Garcia-Fernandez, Alba-Estela, Blanco-Grau, Albert, Mantovani, Alberto, Holten, Aleksander Rygh, Bandera, Alessandra, Cherubini, Alessandro, Protti, Alessandro, Aghemo, Alessio, Gerussi, Alessio, Ramirez, Alfredo, Nebel, Almut, Barreira, Ana, Lleo, Ana, Kildal, Anders Benjamin, Biondi, Andrea, Caballero-Garralda, Andrea, Gori, Andrea, Glück, Andreas, Lind, Andreas, Nolla, Anna Carreras, Latiano, Anna, Fracanzani, Anna Ludovica, Peschuck, Anna, Cavallero, Annalisa, Dyrhol-Riise, Anne Ma, Ruello, Antonella, Muscatello, Antonio, Voza, Antonio, Rando-Segura, Ariadna, Solier, Aurora, Cortes, Beatriz, Mateos, Beatriz, Nafria-Jimenez, Beatriz, Schaefer, Benedikt, Bellinghausen, Carla, Ferrando, Carlos, de la Horra, Carmen, Quereda, Carmen, Scollo, Chiara, Lange, Christoph, Hu, Cinzia, Paccapelo, Cinzia, Angelini, Claudio, Cappadona, Claudio, Bianco, Cristiana, Cea, Cristina, Sancho, Cristina, Hoff, Dag Arne Lihaug, Galimberti, Daniela, Haschka, David, Jiménez, David, Pestaña, David, Toapanta, David, Muñiz-Diaz, Eduardo, Azzolini, Elena, Sandoval, Elena, Binatti, Eleonora, Scarpini, Elio, Casalone, Elisabetta, Urrechaga, Eloisa, Paraboschi, Elvezia Maria, Pontali, Emanuele, Reverter, Enric, Calderón, Enrique J., Navas, Enrique, Contro, Ernesto, Arana-Arri, Eunate, Aziz, Fátima, Sánchez, Félix García, Ceriotti, Ferruccio, Martinelli-Boneschi, Filippo, Peyvandi, Flora, Blasi, Francesco, Malvestiti, Francesco, Medrano, Francisco J., Mesonero, Francisco, Rodriguez-Frias, Francisco, Müller, Fredrik, 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Valsecchi, Maria G., Hernandez-Tejero, María, Vehreschild, Maria J. 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T., Manunta, Maria, Acosta-Herrera, Marialbert, D’Angiò, Mariella, Baldini, Marina, Cazzaniga, Marina, Marquié, Marta, Castoldi, Massimo, Cecconi, Maurizio, Tomasi, Melissa, Boada, Mercè, Joannidis, Michael, Mazzocco, Michela, Ciccarelli, Michele, Rodríguez-Gandía, Miguel, Bocciolone, Monica, Miozzo, Monica, Ayo, Natale Imaz, Blay, Natalia, Chueca, Natalia, Montano, Nicola, Martínez, Nilda, Cornely, Oliver A., Palmieri, Orazio, Faverio, Paola, Preatoni, Paoletta, Bonfanti, Paolo, Omodei, Paolo, Tentorio, Paolo, Castro, Pedro, Rodrigues, Pedro M., Izquierdo-Sanchez, Laura, España, Pedro Pablo, Hoffmann, Per, Bacher, Petra, de Pablo, Raúl, Ferrer, Ricard, Gualtierotti, Roberta, Gallego-Durán, Rocío, Nieto, Rosa, Carpani, Rossana, Morilla, Rubén, Badalamenti, Salvatore, Haider, Sammra, Ciesek, Sandra, Bombace, Sara, Marsal, Sara, Klein, Sebastian, Pelusi, Serena, Wilfling, Sibylle, Goerg, Siegfried, Bosari, Silvano, Brunak, Søren, Heilmann-Heimbach, Stefanie, Aliberti, Stefano, Dudman, Susanne, Zheng, Tenghao, Bahmer, Thomas, Pumarola, Tomas, Cejudo, Trinidad Gonzalez, Rimoldi, Valeria, Monzani, Valter, Skogen, Vegard, Friaza, Vicente, Andrade, Victor, Moreno, Victor, Peter, Wolfgang, Farre, Xavier, Khodamoradi, Yascha, Grimsrud, Marit M., May, Sandra, Colombo, Alicia, Virginia, Monardes-Ramírez A., Dorador, Cristina, Fuentes-Guajardo, Macarena, Silva, Andrea X., Espinosa-Parrilla, Yolanda, Yáñez, Cristian E., Retamales-Ortega, Rocío M., Saez Hidalgo, Juan M., Tobar-Calfucoy, Eduardo A., Carvajal-Silva, Laura, Martínez, Matías F., Cerpa, Leslie C., Christian, Muñoz A., Cappelli, Claudio, Valenzuela-Jorquera, Hector, Zapata-Contreras, Daniela, Zuñiga-Pacheco, Paula, Nova-Lamperti, Estefania A., Sanhueza, Sergio A., Donoso, Gerardo, Bocchieri, Pamela, Kochifas, Pia, Quiñones, Luis A., Pedersen, Ole Birger, Geller, Frank, Westergaard, David, Sequeros, Celia Burgos, Nissen, Janna, Nielsen, Susanne Dam, Feldt-Rasmussen, Ulla, Bliddal, Sofie, Grønbæk, Kirsten, Ullum, Henrik, Ostrowski, Sisse Rye, Feenstra, Bjarke, Shahin, Doaa, Sobh, Ali, Shoma, Ashraf, Nkambul, Lindokuhle, Elhadidy, Tamer A., Abd Elghafar, Mohamed S., El-Jawhari, Jehan J., Mohamed, Attia A. S., Elnagdy, Marwa H., Samir, Amr, Abdel-Aziz, Mahmoud, Khafaga, Walid T., El-Lawaty, Walaa M., Torky, Mohamed S., El-Shanshory, Mohamed R., Elzeiny, Ahmed, Rashad, Amal, Mansour, Tamer A., Yassen, Amr M., Hegazy, Mohamed A. F., Okasha, Kamal, Eid, Mohammed A., Hanteera, Moahmed S., Medina-Gomez, Carolina, Ikram, M. Arfan, Uitterlinden, Andre G., Ripatti, Samuli, Jermy, Bradley, Ruotsalainen, Sanni, Kristiansson, Kati, Koskelainen, Sami, Perola, Markus, Donner, Kati, Kivinen, Katja, Palotie, Aarno, Kaunisto, Mari, Julienne, Hanna, Aschard, Hugues, Deleuze, Jean-Francois, Debette, Stephanie, Tregouet, David-Alexandre, Abel, Laurent, Henches, Léo, Lefloch, Edith, Claire, Dandine-Roulland, Sakuntabhai, Anavaj, Bourgeron, Thomas, Olaso, Robert, Daian, Delphine Bacq, Pellegrin, Isabelle, Casanova, Jean-Laurent, Cobat, Aurélie, Jouanguy, Emmanuelle, Zhang, Qian, Ghosn, Jade, Mentré, France, Laouénan, Cédric, Tubiana, Sarah, Chirouze, Catherine, Quintana-Murci, Luis, Patin, Etienne, Duffy, Darragh, Boland, Anne, Carreras, Anna, Galván-Femenía, Iván, Farré, Xavier, Cortés, Beatriz, Mercader, Josep Maria, Guindo-Martinez, Marta, Torrents, David, Garcia-Aymerich, Judith, Castaño-Vinyals, Gemma, Dobaño, Carlota, van Heel, David A., Hunt, Karen A., Trembath, Richard C., Jacobs, Benjamin Meir, Huang, Qin Qin, Martin, Hilary C., Mason, Dan, Trivedi, Bhavi, Wright, John, Munisamy, Malathy, Finer, Sarah, Griffiths, Christopher J., McCarthy, Mark I., Rosenberger, Carrie, Lee, Jong Eun, Chang, Diana, Hammer, Christian, Hunkapiller, Julie, Mahajan, Anubha, Pendergrass, Rion, Sucheston-Campbell, Lara, Yaspan, Brian, Lee, Hyun Soo, Shin, Eunsoon, Jang, Hye Yoon, Kim, Sunmie, Kym, Sungmin, Kim, Yeon-Sook, Jeong, Hyeongseok, Kwon, Ki Tae, Kim, Shin-Woo, Kim, Jin Yong, Jang, Young Rock, Kim, Hyun ah, Lee, Ji yeon, Lee, Jeong Eun, Lee, Shinwon, Choe, Kang-Won, Kang, Yu Min, Jee, Sun Ha, Jung, Keum Ji, Park, Hyun-Young, Kim, Bong-Jo, Kim, Young Jin, Hwang, Mi Yeong, Yoon, Kyungheon, Pairo-Castineira, Erola, Rawlik, Konrad, Caulfield, Mark J., Baillie, J. Kenneth, Griffiths, Fiona, Bretherick, Andrew D., Stuckey, Alex, Odhams, Christopher A., Walker, Susan, Russell, Clark D., Malinauskas, Tomas, Wu, Yang, Shen, Xia, Elliott, Katherine S., Morrice, Kirstie, Keating, Sean, Wang, Bo, Rhodes, Daniel, Klaric, Lucija, Zechner, Marie, Parkinson, Nick, Fawkes, Angie, Murphy, Lee, Vitart, Veronique, Wilson, James F., Yang, Jian, Scott, Richard H., Moutsianas, Loukas, Law, Andy, Begg, Colin, Hendry, Sara Clohisey, Hinds, Charles, Horby, Peter, Knight, Julian, Ling, Lowell, Maslove, David, McAuley, Danny, Millar, Johnny, Montgomery, Hugh, Nichol, Alistair, Openshaw, Peter J. M., Ponting, Chris P., Rowan, Kathy, Semple, Malcolm G., Shankar-Hari, Manu, Summers, Charlotte, Walsh, Timothy, Pan, Jacqueline, Grau, Neus, Jones, Tim Owen, Lim, Rosario, Marotti, Martina, Whitton, Christopher, Bociek, Aneta, Campos, Sara, Arbane, Gill, Ostermann, Marlies, Cha, Mina, DAmato, Fabiola, Kosifidou, Eirini, Lorah, Shelley, Morera, Kyma, Brady, Laura, Hugill, Keith, Henning, Jeremy, Bonner, Stephen, Headlam, Evie, Jones, Jessica, List, Abigail, Morley, Joanne, Welford, Amy, Kamangu, Bobette, Ratnakumar, Anitha, Shoremekun, Abiola, Alldis, Zoe, Astin-Chamberlain, Raine, Bibi, Fatima, Biddle, Jack, Blow, Sarah, Bolton, Matthew, Borra, Catherine, Bowles, Ruth, Burton, Maudrian, Choudhury, Yasmin, Cox, Amber, Easthope, Amy, Ebano, Patrizia, Fotiadis, Stavros, Gurasashvili, Jana, Halls, Rosslyn, Hartridge, Pippa, Kallon, Delordson, Kassam, Jamila, Lancoma-Malcolm, Ivone, Matharu, Maninderpal, May, Peter, Mitchelmore, Oliver, Newman, Tabitha, Patel, Mital, Pheby, Jane, Pinzuti, Irene, Prime, Zoe, Prysyazhna, Oleksandra, Shiel, Julian, Taylor, Melanie, Tierney, Carey, Zongo, Olivier, Wood, Suzanne, Zak, Anne, Collier, David, Mundy, Manuela, Thompson, Christopher, Pritchard, Lisa, Gellamucho, Minnie, Cartlidge, David, Bandla, Nageswar, Bailey, Lucy, Davies, Michelle, Delaney, Jane, Scott, Leanne, Abdelrazik, Marwa, Alasdair, Frater, Carter, David, Elhassan, Munzir, Ganesan, Arunkumar, Jenkins, Samuel, Lamond, Zoe, Purohit, Dharam, Rohit, Kumar, Saleem, Malik, Wall, Alanna, Xavier, Kugan, Bakthavatsalam, Dhanalaksmi, Gehad, Kirolos, Gnanapragasam, Pakeerathan, Jain, Kapil, Jain, Swati, Malik, Abdul, Pappachan, Naveen, Moreno-Cuesta, Jeronimo, Haldeos, Anne, Vincent, Rachel, Oziegb, Maryjane, Cavazza, Anna, Cockrell, Maeve, Corcoran, Eleanor, Depante, Maria, Finney, Clare, Jerome, Ellen, Knighton, Abigail, Nayak, Monalisa, Pappa, Evita, Saha, Rohit, Saha, Sian, Dodd, Andrew, O’Reilly, Kevin, McPhail, Mark, Clarey, Emma, Noble, Harriet, Smith, John, Coghlan, Phoebe, Brett, Stephen, Gordon, Anthony, Templeton, Maie, Antcliffe, David, Banach, Dorota, Darnell, Sarah, Fernandez, Ziortza, Jepson, Eleanor, Mohammed, Amal, Rojo, Roceld, Arias, Sonia Sousa, Gurung, Anita Tamang, Wong, Jenny, Fernandez-Roman, Jaime, Hamilton, David O., Johnson, Emily, Johnston, Brian, Martinez, Maria Lopez, Mulla, Suleman, Waite, Alicia A. C., Williams, Karen, Waugh, Victoria, Welters, Ingeborg, Emblem, Jessica, Norris, Maria, Shaw, David, Bashyal, Archana, Beer, Sally, Hutton, Paula, McKechnie, Stuart, Davidson, Neil, Mathew, Soya, Readion, Grace, Ryu, Jung, Wilson, Jean, Agrawal, Shruti, Elston, Kay, Jones, Megan, Meaney, Eoghan, Polgarova, Petra, Elbehery, Muhammad, Daubney, Esther, Ng, Anthony, Marshall, Jocelyn, Pathan, Nazima, Stroud, Katerina, White, Deborah, Andrew, Angela, Ashraf, Saima, Clark, Amy, Dent, Martin, Langley, Margaret, Peters, Cecilia, Ryan, Lucy, Sampson, Julia, Wei, Shuying, Baddeley, Alice, Meredith, Megan, Morris, Lucy, Gibbons, Alexandra, McLoughlin, Lisa, Delgado, Carlos Castro, Clark, Victoria, Dawson, Deborah, Ding, Lijun, Durrant, Georgia, Ezeobu, Obiageri, Harrison, Abiola, Hurt, William James, Kanu, Rebecca, Kinch, Ashley, Leaver, Susannah, Lisboa, Ana, Mathew, Jisha, Patel, Kamal, Saluzzio, Romina Pepermans, Rawlins, John, Samakomva, Tinashe, Shah, Nirav, Sicat, Christine, Texeira, Joana, Queiroz, Joana Gomes De, Gloria, Edna Fernandes Da, Maccacari, Elena, Yun, Nikki, Manna, Soumendu, Farnell-Ward, Sarah, Maizcordoba, Maria, Thanasi, Maria, Ali, Hawakin Haji, Hastings, Janice, Grauslyte, Lina, Hussain, Musarat, Ruge, Bobby, King, Sam, Pogreban, Tatiana, Rosaroso, Lace, Smith, Helen, Phull, Mandeep-Kaur, Adams, Nikkita, Franke, George, George, Aparna, Salciute, Erika, Wong, Joanna, Dunne, Karen, Flower, Luke, Sharland, Emma, Sra, Sukhmani, Andrew, Gillian, Callaghan, Marie, Barclay, Lucy, Marshall, Lucy, Amamio, Maria, Birch, Sophie, Briton, Kate, Clark, Sarah, Doverman, Katerine, Hope, Dave, Mcculloch, Corrienne, Simpson, Scott, Singleton, Jo, Fernandez, Rita, Allen, Meryem, Baptista, David, Crowe, Rebecca, Fox, Jonathan, Khera, Jacyntha, Loveridge, Adam, McKenley, India, Morino, Eriko, Naranjo, Andres, O’Connor, Denise, Simms, Richard, Sollesta, Kathryn, Swain, Andrew, Venkatesh, Harish, Herdman-Grant, Rosie, Joseph, Anna, Nown, Angela, Rose, Steve, Pogson, David, Boxall, Helen, Brimfield, Lutece, Claridge, Helen, Daly, Zoe, George, Shenu, Gribbin, Andrew, Cheema, Yusuf, Cutler, Sean, Richards, Owen, Roynon-Reed, Anna, Cherian, Shiney, Heron, Anne Emma, Williams, Gemma, Szakmany, Tamas, Waters, Abby, Collins, Kim, Dunhill, Jill, Jones, Ffion, Morris, Rebecca, Ship, Lucy, Cardwell, Amy, Ali, Syamlan, Bhatterjee, Ravi, Bolton, Rachel, Chukkambotla, Srikanth, Coleman, Dabheoc, Dalziel, Jack, Dykes, Joseph, Fine, Christopher, Gay, Bethan, Goddard, Wendy, Goodchild, Drew, Harling, Rhiannan, Hijazi, Muhammad, Keith, Sarah, Khan, Meherunnisa, Matt, Roseanna, Ryan-Smith, Janet, Saad, Samuel, Springle, Philippa, Thomas, Jacqueline, Truman, Nick, Kazi, Aayesha, Smith, Matthew, Collier, Heather, Davison, Chloe, Duberley, Stephen, Hargreaves, Jeanette, Hartley, Janice, Patel, Tahera, Smith, Ellen, Kent, Alissa, Goodwin, Emma, Zaki, Ahmed, Tibke, Clare, Hopkins, Susan, Gerrard, Hywel, Jackson, Matthew, Bennett, Sara, Marsh, Liane, Mills, Rebecca, Bell, Jessica, Campbell, Helen, Dawson, Angela, Dodds, Steve, Duffy, Stacey, Gallagher, Lisa, McCafferty, Gemma, Short, Stacey, Smith, Tracy, Thomas, Kirsty, Walker, Claire, Reynolds, Jessica, Yates, Bryan, McKie, Hayley, Panteli, Maria, Thompson, Maria, Waddell, Gail, Beger, Sarah De, Abraheem, Azmerelda, Dunmore, Charlie, Girach, Rumanah, Jones, Rhianna, London, Emily, Nagra, Imrun, Nasir, Farah, Sainsbury, Hannah, Smedley, Clare, Brearey, Stephen, Burchett, Caroline, Cawley, Kathryn, Faulkner, Maria, Jeffrey, Helen, Bamford, Peter, Shaikh, Firdaus, Slack, Lauren, Davies, Angela, Brooke, Hollie, Suarez, Jose Cebrian, Charlesworth, Ruth, Hansson, Karen, Norris, John, Poole, Alice, Sandhu, Rajdeep, Smithson, Elizabeth, Thirumaran, Muthu, Wagstaff, Veronica, Buckley, Sarah, Sloan, Brendan, Rose, Alastair, Major, Amy, Metcalfe, Alexandra, Almaden-Boyle, Christine, Austin, Pauline, Chapman, Susan, Eros, Alexandre, Cabrelli, Louise, Cole, Stephen, Whyte, Clare, Casey, Matt, Bafitis, Vasileios, Tsinaslanidis, George, George, Cassandra, Khade, Reena, Black, Christopher, Ashok, Sundar Raj, Farley, Sean, Brinkworth, Elaine, Harford, Rachel, Murphy, Carl, Williams, Marie, Newey, Luke, Toghill, Hannah, Lewis, Sophie, Rees, Tabitha, Battle, Ceri, Baker, Mark, Travers, Jenny, Chesters, Karen, Baxter, Nicola, Arnott, Andrew, McCreath, Gordan, McParland, Christopher, Rooney, Laura, Sim, Malcolm, Henderson, Steven, Abel, Lynn, Dalton, Carol, Kennedy-Hay, Sophie, O’Donohoe, Lynn, O’Hare, Megan, Orlikowska, Izabela, Parker, Natasha, McNeela, Fiona, Lyle, Amanda, Hughes, Alistair, Radhakrishnan, Jayachandran, Gibson, Sian, Bancroft, Hollie, Bellamy, Mary, Daglish, Jacqueline, Kadiri, Salma, Moore, Faye, Rhodes, Joanne, Sangombe, Mirriam, Peterkin, Zhane, Scriven, James, Carmody, Margaret, Cottle, Juliet, Peasgood, Emily, de Gordoa, Laura Ortiz-Ruiz, Phillips, Claire, Skinner, Denise, Cinquina, Zoe, Howard, Kate, Joy, Rosie, Roche, Samantha, Birkinshaw, Isobel, Carter, Joseph, Ingham, Jo, Marshall, Nicola, Pearson, Harriet, Scott, Zoe, Dasgin, Jo, Gill, Jaspret, Nilsson, Annette, Bamford, Amy, Hull, Diana, Ahmadhaider, Nafeesah, Bates, Michelle, McGhee, Christopher, Ellis, Hannah, Howe, Gwenllian Sera, Singh, Jayaprakash, Stroud, Natalie, Roche, Lisa, Lynch, Ceri, Deacon, Bethan, Pothecary, Carla, Smeaton, Justyna, Agravante, Kevin, Krishnamurthy, Vinodh, Diaba, Cynthia, John, Lincy, Lim, Lai, Jha, Rajeev, Egan, Jasmine, Felton, Timothy, Glasgow, Susannah, Padden, Grace, Choudhr, Ozerah, Bradley-Potts, Joanne, Moss, Stuart, Lingeswaran, Saejohn, Alexander, Peter, Brandwood, Craig, Fiouni, Sofia, Ward, Luke, Allen, Schvearn, Shaw, Jane, Smith, Christopher, Adanini, Oluronke, Collins, Rebecca, Msiska, Maines, Ofori, Linda, Bhatia, Nikhil, Dolan, Hayley, Brunton, Mark, Caterson, Jess, Coles, Holly, Keating, Liza, Tilney, Emma, Jacques, Nicola, Frise, Matthew, Armistead, Jennifer, Bartley, Shauna, Bhuie, Parminder, Rai, Sabi, Tomkova, Gabriela, Greer, Sandra, Shuker, Karen, Tridente, Ascanio, Dobson, Emma, Hunt, Jodie, Tully, Redmond, Dearden, Joy, Drummond, Andrew, Kamath, Prakash, Bullock, Emily, Mulcahy, Michelle, Munt, Shelia, O’Connor, Grainne, Philbin, Jennifer, Rishton, Chloe, Scott, Chloe, Winnard, Sarah, Hasni, Nurkamalia, Gascoyne, Rachel, Hawes, Joanne, Pritchard, Kelly, Stevenson, Lesley, Whileman, Amanda, Beavis, Sarah, Bishop, Lauren, Cart, Cindy, Dale, Katie, Kelly-Baxter, Mary, Mendelski, Adam, Moakes, Emma, Smith, Rheanna, Woodward, Jan, Wright, Stephanie, Allan, Angela, Botello, Adriana, Liew, Jade, Medhora, Jasmine, Trumper, Erin, Savage, Felicity, Scott, Teresa, Place, Marc, Kaye, Callum, Benyon, Sarah, Marriott, Suzie, Park, Linda, Quinn, Helen, Skyes, Daisy, Zitter, Lily, Baines, Kizzy, Gordon, Elizabeth, Keenan, Samantha, Pitt, Andrew, Duffy, Katharine, Ireland, Jane, Semple, Gary, Turner, Lynne, Cathcart, Susanne, Rimmer, Dominic, Puxty, Alex, Puxty, Kathryn, Hurst, Andrew, Miller, Jennifer, Speirs, Susan, Walker, Lauren, Bradshaw, Zena, Brown, Joanna, Melling, Sarah, Preston, Stephen, Slawson, Nicola, Warden, Scott, Beasley, Alanna, Stoddard, Emma, Benham, Leonie, Cupitt, Jason, Caswell, Melanie, Elawamy, Lisa, Wignall, Ashleigh, Roberts, Belinda, Golding, Hannah, Leggett, Samantha, Male, Michelle, Marani, Martyna, Prager, Kirsty, Williams, Toran, Golder, Kim, Jones, Oliver, Cusack, Rebecca, Bolger, Clare, Burnish, Rachel, Carter, Michael, Jackson, Susan, Salmon, Karen, Biss, Jonathan, Aquino, Maia, Croft, Maria, Frost, Victoria, White, Ian, Govender, Keshnie, Webb, Natasha, Stapleton, Liana, Wells, Colin, Nikitas, Nikitas, Sanchez - Rodriguez, Ana, Spencer, Kayleigh, Stowe, Bethan, Izzard, Yvonne, Poole, Michelle, Monnery, Sonja, Trotman, Sallyanne, Beech, Valerie, Combes, Edward, Joefield, Teishel, Covernton, Patrick, Savage, Sarah, Woodward, Elizabeth, Camsooksai, Julie, Reschreiter, Henrik, Barclay, Charlotte, DeAth, Yasmin, Dube, Judith, Humphrey, Charlotte, Jenkins, Sarah, Langridge, Emma, Milne, Rebecca, Wadams, Beverley, Woolcock, Megan, Brett, Michael, Digby, Brian, Gemmell, Lisa, Hornsby, James, MacGoey, Patrick, O’Neil, Pauline, Price, Richard, Sundaram, Radha, Rodden, Natalie, Thomson, Nicola, Rooney, Kevin, Currie, Susan, Henderson, Philip, Ogg, Bethan, Whiteley, Simon, Wilby, Liz, Long, Kate, Matthew, Shailamma, Salada, Sheila, Trott, Susan, Watts, Sarah, Friar, Zoe, Speight, Abigail, Bastion, Victoria, Chandna, Humza, Djeugam, Brice, Haseeb, Muhammad, Kent, Harriet, Lubimbi, Gamu, Murdoch, Sophie, Thomas, Alastair, David, Beena, Lorusso, Rachel, Vochin, Ana, Penacerrada, Melchizedek, Wulandari, Retno, Heath, Charlotte, Jakkula, Srinivas, Morris, Anna, Ahmed, Ashar, Nune, Arvind, Buttriss, Claire, Whitaker, Emma, Davey, Miriam, Golden, David, Acklery, Amy, Fernandes, Fabio, Seaman, Bec, Earl, Victoria, Collins, Amy, Khaliq, Waqas, Adam, Rachel, Treus, Estefania, Holland, Sarah, Alfonso, Jordan, Blackledge, Bethan, Bruce, Michelle, Durrans, Laura Jayne, Eltayeb, Ayaa, Harris, Jade, Hey, Samuel, Hruska, Martin, Lamb, Thomas, Rothwell, Joanne, Fitzgerald, Adele, Lindergard, Gabriella, T-Michael, Helen, Duncan, Tracey, Baxter-Dore, Sharon, Cooper, Lisa, Fox, Claire, Guerin, Jacinta, Hodgkiss, Tracey, Connolly, Karen, McAlinden, Paul, Bridgett, Victoria, Fearby, Maggie, Gulati, A., Hanson, Helen, Kelly, Sinead, McCormack, Louise, Nixon, Rachel, Robinson, Philip, Slater, Victoria, Stephenson, Elaine, Webster, Andrea, Webster, K., Hays, Carole, Hudson, Anne, Patel, Bijal, Clement, Ian, Davis, John, Francis, Sarah, Jerry, Douglas, Abernathy, Caroline, Foster, Louise, Gratrix, Andrew, Cabral-Ortega, Llucia, Hines, Matthew, Martinson, Victoria, Stones, Elizabeth, Winter, Karen, Barrow, Esther, Wylie, Katharine, Baines, Deborah, Birchall, Katie, Kolakaluri, Laurel, Clark, Richard, Sukumaran, Anila, Barker, Melanie, Paripoorani, Deborah, Smith, Lara, Taylor, Charlotte, Downes, Charlotte, Hayman, Melanie, Riches, Katie, Daniel, Priya, Subramanian, Deepak, Holding, Kathleen, Hilton, Mary, Mcdonald, Carly, Richardson, Georgina, Halladay, Georgia, Harding, Peter, Reddy, Amie, Turner-Bone, Ian, Wilding, Laura, Parker, Robert, Lloyd, Michaela, Smith, Leanne, Kelly, Charlie, Lazo, Maria, Neal, Alan, Walton, Olivia, Melville, Julie, Naisbitt, Jay, Joseph, Rosane, Callam, Sara, Hudig, Lisa, Keshet-Price, Jocelyn, Stammers, Katie, Convery, Karen, Randell, Georgina, Fottrell-gould, Deirdre, Mwaura, Esther, Sutherland, Sara-Beth, Stewart, Richard, Mew, Louise, Wren, Lynn, Thrasyvoulou, Laura, Willis, Heather, Hopkins, Bridget, Lenton, Daniel, Roberts, Abigail, Bokhari, Maria, Lucas, Rachael, McCormick, Wendy, Ritzema, Jenny, Linnett, Vanessa, Sanderson, Amanda, Wild, Helen, Flanagan, Rebecca, Hull, Robert, Rhead, Kat, McKenna, Emma, Hughes, Gareth, Anderson, Jennifer, Jones, Kelly, Latham, Scott, Riley, Heather, Coulding, Martina, Clark, Martyn, McCormick, Jacqueline, Mercer, Oliver, Potla, Darsh, Rehman, Hafiz, Savill, Heather, Turner, Victoria, Jude, Edward, Kilroy, Susan, Apetri, Elena, Basikolo, Cathrine, Catlow, Laura, Collis, Matthew, Doonan, Reece, Harvey, Alice, Knowles, Karen, Lee, Stephanie, Lomas, Diane, Lyons, Chloe, McMorrow, Liam, Michael, Angiy, Pendlebury, Jessica, Perez, Jane, Poulaka, Maria, Proudfoot, Nicola, Slevin, Kathryn, Thomas, Vicky, Walker, Danielle, Dark, Paul, Charles, Bethan, McLaughlan, Danielle, Slaughter, Melanie, Horner, Dan, Marsden, Tracy, Andrews, Joyann, Beech, Emily, Akinkugbe, Olugbenga, Bamford, Alasdair, Belfield, Holly, Jones, Gareth A. L., McHugh, Tara, Meghari, Hamza, Ray, Samiran, Tomas, Ana Luisa, O’Neill, Lauran, Peters, Mark, Bell, Michael, Benkenstein, Sarah, Chisholm, Catherine, Davies, Charlene, Kupiec, Klaudia, Payne, Caroline, Halls, Joanna, Blakemore, Hayley, Goff, Elizabeth, Hayes, Kati, Smith, Kerry, Stephens, Deanna, Worner, Ruth, Borislavova, Borislava, Faulkner, Beverley, Thomas, Matt, Cookson, Ruth, Gendall, Emma, Larman, Georgina, Pope, Rebecca, Smalira, Artur, Priestley, Victoria, Cosier, Tracey, Millen, Gemma, Rand, James, Schumacher, Natasha, Sandhar, Roxana, Weston, Heather, Richardson, Neil, Cooper, Lucy, Jones, Cathy, Huang, Ya-Wen Jessica, Jacob, Reni, Denmade, Craig, Mcintyre, Lewis, Trodd, Dawn, Martin, Jane, Watson, Geoff, Bevan, Emily, Wreybrown, Caroline, Bano, Shereen, Bellwood, Ruth, Bentley, Michael, Bromley, Matt, Gurr, Lucy, Ledgard, Camilla, McGowan, Janet, Pye, Kate, Sellick, Kirsten, Stacey, Amelia, Warren, Deborah, Wilkinson, Brian, Akeroyd, Louise, Shafique, Huma, Morgan, James, Shorter, Susan, Swinger, Rachel, Waters, Emily, Lawton, Tom, Allan, Elizabeth, Darlington, Kate, Davies, Ffyon, Davies, Llinos, Easton, Jack, Kumar, Sumit, Lean, Richard, Mackay, Callum, Pugh, Richard, Qiu, Xinyi, Rees, Stephanie, Scanlon, Jeremy, Lewis, Joanne, Menzies, Daniel, Bolger, Annette, Davies, Gwyneth, Davies, Jennifer, Garrod, Esther, Jones, Helen, Manley, Rachel, Williams, Hannah, Frankham, Jordan, Pitts, Sally, White, Nigel, Branney, Debbie, Tiller, Heather, Efford, Georgia, Garland, Zoe, Grimmer, Lisa, Gumbrill, Bethany, Johnson, Rebekah, Sweet, Katie, Bewley, Jeremy, Coleman, Christina, Corcoran, Katie, Morano, Eva Maria Hernandez, Shiel, Rachel, Webster, Denise, Bonnici, Josephine, Daniel, Eleanor, Dell, Abbie, Kent, Melanie, Wilkinson, Ami, Brown, Ellen, Kay, Andrea, Campbell, Suzanne, Cowton, Amanda, Birt, Mark, Greenaway, Vicki, Potts, Kathryn, Hutton, Clare, Shepperson, Andrew, Forsey, Miranda, Nicholson, Alice, Vertue, Mark, Riches, Joanne, Kaliappan, Agilan, Nicholson, Anne, MacCallum, Niall, Raith, Eamon, Bercades, Georgia, Hass, Ingrid, Brealey, David, Martir, Gladys, Reyes, Anna, Smyth, Deborah, Zapatamartinez, Maria, Alvaro, Ana, Jetha, Champa, Ma, Louise, Booker, Lauren, Mostoles, Loreta, Pratley, Anezka, Altabaibeh, Abdelhakim, Parmar, Chetan, Gilbert, Kayleigh, Ferguson, Susie, Shepherd, Amy, Morris, Sheila, Baruah, Rosie, Lloyd, Georgina, Bell, Stephanie, Rivers, Vanessa, Purewal, Bally, Hammerton, Kate, Anderson, Susan, Birch, Janine, Collins, Emma, Oleary, Ryan, Cornell, Sarah, Jarmain, Jordan, Rogerson, Kimberley, Wakinshaw, Fiona, Woods, Lindsey, Rostron, Anthony, Elcioglu, Zeynep, Roy, Alistair, Bell, Gillian, Dickson, Holly, Wilcox, Louise, Katary, Amro, English, Katy, Hutter, Joanne, Pawley, Corinne, Doble, Patricia, Shovelton, Charmaine, Vaida, Marius, Purnell, Rebecca, Thomas, Ashly, Cagova, Lenka, Fofano, Adama, Holcombe, Helen, Mitchell, Alice Michael, Mwaura, Lucy, Praman, KrithivasanÂ, Garnr, Lucie, Mepham, Sue, Paques, Kitty, Vuylsteke, Alain, Mackie, Jennifer, Pearn, Carmen, Zamikula, Julie, Nyirenda, Maggie, Capozzi, Lisa, Reece-Anthony, Rosie, Noor, Hazma, Nilo, Alfa Cresia, Grove, Michelle, Daniel, Amelia, Finn, Joanne, White, Nikki, Saha, Rajnish, Badal, Bibi, Ixer, Karen, Duffin, Donna, Player, Ben, Hill, Helen, Cole, Jade, Brooks, Jenny, Davies, Rhys, Hunt, Lauren, Thomas, Emma, Williams, Angharad, Oblak, Metod, Thankachen, Mini, Irisari, Jamie, Sayan, Amrinder, Popescu, Monica, Finch, Cheryl, Jamieson, Andrew, Quinn, Alison, Cooper, Joshua, Liderth, Sarah, Waddington, Natalia, Burn, Iona, Manso, Katarina, Penn, Ruth, Tebbutt, Julie, Thornton, Danielle, Winchester, James, Hambrook, Geraldine, Shanmugasundaram, Pradeep, Craig, Jayne, Simpson, Kerry, Higham, Andrew, Sibbett, Louise, Paine, Sheila, Reed, Annabel, Conyngham, Jo-Anna, Mupudzi, Mcdonald, Thomas, Rachel, Wright, Mary, Griffin, Denise, Partridge, Richard, Corral, Maria Alvarez, Muchenje, Nycola, Sitonik, Mildred, Butler, Aaron, Folkes, Linda, Fox, Heather, Gardner, Amy, Helm, David, Hobden, Gillian, King, Kirsten, Margalef, Jordi, Margarson, Michael, Martindale, Tim, Meadows, Emma, Raynard, Dana, Thirlwall, Yvette, Baird, Yolanda, Gomez, Raquel, Martin, Darren, Hodgson, Luke, Corin, Clinton, Sidall, Erikka, Szabo, Densie, Floyd, Sharon, Davies, Hannah, Austin, Karen, Kelsall, Olivia, Wood, Hannah, Cornell, Thomas, Ralph, Kate, Bean, Sarah, Burt, Karen, Spivey, Michael, Richards, Carol, Tedstone, Rachel, Carmody, Siobhain, Zhao, Xiaobei, Page, Valerie, Guanco, Mark Louie, Hoxha, Elvira, Zorloni, Camilla, Dean, Charlotte, Jones, Emma, Carter, Emma, Dunn, Joshua, Kong, Thomas, Mahenthran, Mervin, Marsh, Chris, Holland, Maureen, Keenan, Natalie, Mahmoud, Mohamed, Lyons, Marc, Wassall, Helen, Young, Meghan, Bradley, Paul, Burda, Dorota, Donlon, Sinead, Harden, Lesley, Harris, Celia, Mayangao, Irving, Montaser, Rugia, Mtuwa, Sheila, Piercy, Charles, Smith, Eleanor, Stone, Sarah, Verula, Jerik, Blackman, Helen, Marriott, Cheryl, Michalak, Natalia, Creagh-Brown, Ben, Salberg, Armorel, Boyer, Naomi, Pristopan, Veronika, Maynard, Victoria, Walker, Rachel, Hormis, Anil, Collier, Dawn, Graham, Cheryl, McCormick, Jake, Warrington, Jake, Cosgrove, Denise, McFarland, Denise, Ratcliffe, Judith, Charnock, Rob, Wynter, Inez, Gill, Mandy, Kirk, Jill, Paul, Paul, Ratnam, Valli, Shelton, Sarah, Jardine, Catherine, Hay, Alasdair, Williams, Dewi, Durga, Latha, Hibbert, Meg, Kennard-Holden, Gareth, Woodford, Chrsitopher, Tetla, Dariusz, Price, Alicia, Thomas, Alice, Thorpe, Chris, Knights, Ellen, Ward, Donna, Laha, Shondipon, Verlander, Mark, Williams, Alexandra, Prout, Rachel, Langton, Helen, Watters, Malcolm, Hunt, Charlotte, Novis, Catherine, Arif, Sarwat, Cunningham, Amy, Hewitt, Claire, Hindale, Julia, Jackson-Lawrence, Karen, Shepardson, Sarah, Wills, Maryanne, Butler, Susie, Tavares, Silivia, Barber, Russell, Hilldrith, Annette, Hubbard, Kelly, Egginton, Dawn, Clark, Michele, Purvis, Sarah, Sinclair, Simon, Collins, Vicky, Landeg, Bethan, Sell, Craig, Coetzee, Samantha, Gales, Alistair, Otahal, Igor, Icke, Becky, Raj, Meena, Williams, Caroline, Williams, Jill, Hill, Lucy, Kayani, Abdul, Masunda, Bridgett, Gondo, Prisca, Atayeva, Nigara, Cruz, Carina, Pattison, Natalie, Burnett, Caroline, Hatton, Jonathan, Heeney, Elaine, Newton, Maria, Al-Moasseb, Hassan, Behan, Teresa, Player, Jasmine, Stead, Rachael, Mitra, Atideb, Nauyokas, Kirsty, Humphreys, Sally, Cockerill, Helen, Tampsett, Ruth, Postovalova, Evgeniya, Coventry, Tina, McGregor, Amanda, Fowler, Susan, Macmahon, Mike, Cochrane, Patricia, Pirie, Sandra, Hanley, Sarah, Ali, Asifa, Brady, Megan, Dale, Sam, Dance, Annalisa, Gledhill, Lisa, Greig, Jill, Hanson, Kathryn, Holdroyd, Kelly, Home, Marie, Ishaq, Tahira, Kelly, Diane, Matapure, Lear, Melia, Deborah, Mellor, Samantha, Merwaha, Ekta, Nortcliffe, Tonicha, Shaw, Lisa, Shaw, Ryan, Wood, Tracy, Bayo, Lee-Ann, Usher, Miranda, Wilson, Alison, Kitson, Ross, Pinnell, Jez, Robinson, Matthew, Boltwood, Kaitlin, Birch, Jenny, Bough, Laura, Tutton, Rebecca, Winter-Goodwin, Barbara, Goodsell, Josie, Taylor, Kate, Williams, Patricia, Williams, Sarah, Cave, Ashleigh, Rees, James, Imeson-Wood, Janet, Smith, Jacqueline, Amin, Vishal, Karthik, Komala, Kausar, Rizwana, Anastasescu, Elena, Reid, Karen, Anumakonda, Vikram, Stoddart, Ella, Demetriou, Carrie, Eckbad, Charlotte, Howie, Lucy, Mitchard, Sarah, Ramos, Lidia, White, Katie, Hierons, Sarah, Kelly, Fiona, Serrano-Ruiz, Alfredo, Evans, Gabrielle, Nicol, Liz, Wilkins, Joy, Hulacka, Kim, Debreceni, Gabor, Brown, Alison, Crickmore, Vikki, Hill, Kay, Kannan, Thogulava, Dagutao, Zenaida, Beesley, Kate, Lewis, Alison, Perry, Jess, Antony, Sherly, Board, Sarah, Buckley, Clare, Pippard, Lucy, Tanate, Alfonso, Wood, Diane, Kubisz-Pudelko, Agnieska, Gouda, Ayman, Auld, Fiona, Donnachie, Joanne, Murdoch, Euan, Prentice, Lynn, Runciman, Nikole, Senaratne, Dhaneesha, Short, Abigail, Sweeney, Laura, Symon, Lesley, Todd, Anne, Turner, Patricia, McCann, Erin, Salutous, Dario, Edmond, Ian, Whitelaw, Lesley, Bland, Yvonne, Kajtor, Istvan, Kavanagh, Lisa, Singler, Karen, Linfield-Brown, George, Moore, Luke Stephen Prockter, Vizcaychipi, Marcela, Martins, Laura, Moore, Luke, Bull, Rhian, Carungcong, Jaime, Allen, Louise, Beranova, Eva, Knight, Alicia, Price, Carly, Tilbey, Sorrell, Turney, Sharon, Hazelton, Tracy, Tutt, Gabriella, Arora, Mansi, Turki, Salah, Sinfield, Emily, Deery, Joanne, Ramos, Hazel, Cristiano, Daniele, Dormand, Natalie, Farzad, Zohreh, Gummadi, Mahitha, Salmi, Sara, Sloane, Geraldine, Varghese, Mathew, Thwaites, Vicky, Patel, Brijesh, Kamal, Liyanage, Zborowski, Anelise Catelan, Coe, Ryan, Anderson, Madeleine, Beadle, Jane, Coates, Charlotte, Collins, Katy, Crowley, Maria, Johnson, Laura, King, Laura, Paramsothy, Remi, Sargeant, Janet, Silva, Pedro, Stuart, Carmel, Taylor, June, Tyl, David, Wakefield, Phillipa, Kamundi, Charlotte, Olufuwa, Olumide, Belagodu, Zakaulla, Gherman, Anca, Oakley, Naomi, Allan, John, Geary, Tim, Meikle, Alistair, O’Brien, Peter, Wood, Stephen, Clark, Andrew, Houston, Gordon, Black, Karen, Clarkson, Michelle, D’Sylva, Stuart, Morrison, Alan, Norman, Kathryn, Taylor, Margaret, Clements, Suzanne, Cohrane, Catriona, Gonzalez, Nora, Strachan, Dominic, Beith, Claire, Moar, Kirsten, Anderson, Peter, Archer, Katie, Burtenshaw, Andrew, Clayton, Sarah, Cother, Naiara, Cowley, Nicholas, Davis, Caroline, Digby, Stephen, Durie, Alison, Harrison, Alison, Low, Emma, McAlindon, Michael, McCurdy, Alex, Morgan, Aled, Rankin, Tobias, Thrush, Jessica, Tranter, Helen, Vigurs, Charlie, Wild, Laura, Murphy, Lorna, Smythe, Michelle, Brickell, Kathy, Ali, Inthakab Ali Mohamed, Beaumont, Karen, Elsaadany, Mohamed, Fernandes, Kay, Ally, Sameena Mohamed, Rangarajan, Harini, Sarathy, Varun, Selvanayagam, Sivarupan, Vedage, Dave, White, Matthew, Coton, Zoe, Joshy, Aricsa, Blunt, Mark, Curgenven, Hollie, Botfield, Liam, Dexter, Catherine, Kuravi, Aditya, Butler, Joanne, Chadwick, Robert, Ranga, Poonam, Richardson, Lisa, Virgilio, Emma, Anwer, Maddiha, Garg, Atul, Botfield, Donna, Marriott, Xana, Stewart, Keely, Mullan, Dee, Gaylard, Jane, Nowak, Justyna, Jones, Sian, Crawley, Rikki, Crew, Abigail, Cunningham, Mishell, Daniels, Allison, Harrison, Laura, Hope, Susan, Lancaster, Nicola, Matthews, Jamie, Wray, Gemma, Inweregbu, Ken, Cutts, Sarah, Miller, Katharine, Brady, Ailbhe, Chan, Rebekah, McIvor, Shane, Prady, Helena, Mathew, Bijoy, Little, Jeff, Furniss, Tim, Wright, Chris, King, Bernadette, Wasson, Christopher, O’Neill, Aisling, Turley, Christine, McGuigan, Peter, Collins, Erin, Finn, Stephanie, Green, Jackie, McAuley, Julie, Nair, Abitha, Quinn, Charlotte, Tauro, Suzanne, Ward, Kathryn, McGinlay, Michael, Reddy, Kiran, Ahmad, Norfaizan, Anderson, Samantha, Barker, Joann, Bauchmuller, Kris, Birchall, Kathryn, Bird, Sarah, Cawthron, Kay, Chetam, Luke, Cole, Joby, Donne, Ben, Foote, David, Ford, Amber, Hanratty, Helena, Harrington, Kate, Hesseldon, Lisa, Housley, Kay, Jackson, Yvonne, Jarman, Claire, Kibutu, Faith, Lenagh, Becky, Macharia, Irene, Masuko, Shamiso, Milner, Leanne, Newell, Helen, Nwafor, Lorenza, Oxspring, Simon, Phillips, Patrick, Raithatha, Ajay, Rowland-Jones, Sarah, Smith, Jacqui, Thompson, Roger, Trower, Helen, Walker, Sara, Watson, James, Wiles, Matthew, Lye, Alison, Willson, Jayne, Mills, Gary, Harris, Sansha, Hartill, Eleanor, Barron, Anthony, Collins, Ciara, Kaul, Sundeep, Nolan, Claire, Polgar, Oliver, Prendergast, Claire, Rogers, Paula, Shokkar, Rajvinder, Woodruff, Meriel, Mahay, Kanta, Reed, Anna, Meyrick, Hayley, Passmore, Heather, Farwell, James, O’Connell, Susan, Gregory, Jane, Barberis, Luigi, Harper, Rosemary, Smith, Tim, Armstrong, Diane, Bowey, Angie, Cowley, Anne, Corner, Andrew, Highgate, Judith, Rutherfurd, Claire, Taylor, Jo-Anne, Goodwin, Sarah, Eapen, Beena, Trim, Fiona, Donnison, Phil, Armstrong, Lisa, Bates, Hayley, Dooks, Emma, Farquhar, Fiona, Kitching, Amy, McParland, Chantal, Packham, Sophie, Hairsine, Brigid, Andreou, Premetie, Hales, Dawn, Mathews, Megha, Patel, Rekha, Barry, Peter, Flint, Neil, Hailstone, Jessica, Ghuman, Navneet, Leonard, Bethany, Lees, Rachel, Butcher, Deborah, Leng, Katy, Butterworth-Cowin, Nicola, O’Sullivan, Susie, Ghosh, Alison, Williams, Emma, Adams, Colene, Agasou, Anita, Arden, Tracie, Beekes, Mandy, Bowes, Amy, Boyle, Pauline, Button, Heather, Carnahan, Mandy, Carter, Anne, Childs, Danielle, Hurford, Fran, Hussain, Yasmin, Javaid, Ayesha, Jones, James, Leigh, Michael, Martin, Terry, Millward, Helen, Motherwell, Nichola, Newman, Julie, Rikunenko, Rachel, Stickley, Jo, Summers, Julie, Ting, Louise, Tivenan, Helen, Donaldson, Denise, Capps, Nigel, Cale, Emily, Jose, Sanal, Osbourne, Wendy, Pajak, Susie, Rankin, Jayne, Tonks, Louise, Baird, Tracy, Harkins, Margaret, Ruddy, Jim, West, Joe, Duffield, Joseph, Mallon, Lewis, Smith, Oliver, Smuts, Sara, Campbell, Andy, Davies, Cate, Davies, Sarah, Hughes, Rachel, Jobes, Lisa, Whitehead, Victoria, Watkins, Clare, Bowman, Fiona, Milligan, Barry, McPherson, Liane, Metherell, Stella, Harris, Nichola, Lake, Victoria, Radford, Elizabeth, Smallwood, Andy, Gopal, Shameer, Vassell, Katherine, Bell, Dina, Boyle, Rosalind, Douglas, Katie, Glass, Lynn, Lennon, Liz, Rattray, Austin, Lee, Emma, Jones, Danielle, Parsons, Penny, Attwood, Ben, Jefferson, Paul, Ranganathan, Mohan, Atwal, Inderjit, Campbell, Bridget, Day, Angela, Stagg, Camilla, Haynes, Emma, Ahmed, Cecilia, Clamp, Sarah, Colley, Julie, Haq, Risna, Hayes, Anne, Joseph, Sibet, Maqsood, Zahira, Hussain, Samia, Hulme, Jonathan, Domingos, Patience, Kumar, Rita, Purewal, Manjit, Taylor, Becky, Bunni, Lara, Latif, Monica, Jennings, Claire, Jose, Shilu, Marshall, Rebecca, Metryka, Aleksandra, Subramanian, Gayathri, Burgoyne, Adam, Tyler, Amanda, Waldron, Joanne, Hilltout, Paula, Evitts, Jayne, Ward, Geraldine, Bremmer, Pamela, Hawkins, Carl, Jackman, Sophie, Ogorek, Michal, Ashby, Kylie, Thornton, Lorraine, Mercer, Pauline, Halkes, Matthew, Revill, Adam, Saint, Bryony, Fletcher, Jo, Netherton, Kimberley, Chablani, Manish, Kirkby, Amy, Roper, Amanda, Szymiczek, Kinga, Sutherland, Isobel, O’Brien, Linda, Connell, Joanne, Davies, Kim, Lewis, Tracy, Omar, Zohra, Perkins, Emma, Sathe, Sonia, Davies, Ellie, Lyon, Alex, Mapfunde, Isheunesu, Willis, Charlotte, Hitchcock, Rachael, Hall, Kathryn, King, Christopher, Fagan, Andrew, Nazari, Roonak, Worsley, Lucy, Allibone, Suzanne, Kasipandian, Vidya, Patel, Amit, Cutting, Parisa, Genetu, Roman, Mac, Ainhi, Murphy, Anthony, Ward, Sinead, Butt, Fatima, Ayers, Amanda, Harrison, Wendy, Mackintosh, Katherine, North, Julie, Ashton, Lydia, Bi, Rehana, Owen, Samantha, Winmill, Helen, Scholefield, Barney, Blowing, Hannah, Williams, Erin, Duskova, Michaela, Edwards, Michelle, Rees, Alun, Thomas, Helen, Brooks, Jolene, Phipps, Janet, Brooks, Suzanne, Dennis, Catherine, Parris, Vicki, Srikaran, Sinduya, Sukha, Anisha, McGregor, Alistair, Tiongson, Gerlynn, Adams, Katie, Andrew, Benedict, Brayne, Adam, Carter, Sasha, Findlay, Louise, Fisher, Emma, Jackson, Peter, Kaye, Duncan, Parkin, Juliet, Tuckey, Victoria, Hunt, Jane, Love, Nicholas, van Koutrick, Lynne, Hanson, Ashley, Dent, Kathy, Horsley, Elizabeth, Pearson, Sandra, Spencer, Sue, Hutchinson, Dorothy, Potoczna, Dorota, Akhtar, Muhammad Nauman, Cottam, Lisa-Jayne, Sanders, Jack, Garcia, Sara Mingo, pakou, Glykeria, Filipe, Helder, Maharajh, Amitaa, de Neef, Mark, Martin, Daniel, Eastgate, Christine, Teoh, Poh Choo, Barrett, Fiona, Bradley, Clare, Donaldson, Avril, Mascarenhas, Mairi, O’Hara, Marianne, Okeefe, Laura, Clarke, Noreen, Whiteside, Jonathan, Campbell, Rachael, Matheson, Joanna, McDonald, Deborah, Patience, Donna, Rice, Polly, Clapham, Melanie, Mutch, Rachel, Craig, Hannah, Poultney, Una, Burns, Karen, Twiss, Sophie, Barton, Janet, George, Linsha, Harrop, Clare, Mathew, Sherly, Wright, David Justin, Harrison, Rachel, Toohie, Jordan, Chandler, Ben, Turnbull, Alison, Mallinson, Janine, Elliott, Kerry, Wolf-Roberts, Rebecca, Tench, Helen, Hobrok, Maria, Loosley, Ronda, McGuinness, Heather, Sims, Tanya, Afolabi, Deborah, Allison, Kathryn Sian, Anderson, Taya, Dore, Rachael, Jones, Dawn, Rogers, Naomi, Saunderson, Paula, Whitbread, Jennifer, O’Malley, Laura, Rad, Laura, Hawcutt, Daniel, Aldridge, Jonathan, Tolson, Melanie, Garrioch, Sweyn, Tomlinson, Joanne, Grosdenier, Michael, Loader, David, Kapoor, Ritoo, Hector, Gemma, Scherewode, Joslan, Sri-Chandana, Chunda, Stephenson, Lorraine, Marsh, Sarah, Rosa, Arnold Dela, Jhanji, Shaman, Bemand, Thomas, Howle, Ryan, Baikady, Ravishankar Rao, Thomas, Benjamin, Black, Ethel, Tatham, Kate, Gurram, Sambasivarao, Watson, Ekaterina, Quaid, Sheena, Saunderson, Anne, O’Brien, Rachel, Moultrie, Sam, Service, Jen, Cheyne, Clare, Odam, Miranda, Wiliams, Alison, Barnes, Nicky, Csabi, Peter, Rocha, Joana Da, Glynou, Louika, Huffenberger, Amy, Bryant, Jade, Pickard, Amy, Roe, Nicholas, Bellini, Arianna, Mayer, Anton, Burrow, Amy, Colley, Natalie, Evans, Jayne, Howlett, Alex, Khalifeh, Zeinab, Pryce, Jerldine, Gorman, Claire, Brady, Rebecca, Timlick, Elizabeth, Antoine, Pierre, Gupta, Abhinhav, Hardy, John, Houlden, Henry, Moncur, Eleanor, Tucci, Arianna, Tariq, Ambreen, Tagliavini, Emma, Ramsay, Becky, Fidler, Katy, Donnelly, Kevin, Hollis, Rebecca, Barr, Jocelyn, Boyd, Elizabeth, Irvine, Val, Shelley, Ben, Buckley, Julie, Hamilton, Charlene, Valdeavella, Kathryn, Bircham, Sarah, Liggett, Steven, Patil, Anand, Siddiq, Afshan, Goddard, Peter, Donovan, Sally, Zainy, Tala, Maleady-Crowe, Fiona, Todd, Linda, Salehi, Shahla, Elgar, Greg, Chan, Georgia, Arumugam, Prabhu, Patch, Christine, Rendon, Augusto, Bentley, David, Kingsley, Clare, Fowler, Tom A., Elliott, Paul, Tenesa, Albert, Aitkin, Emma, Aravindan, Latha, Armstrong, Ruth, Biggs, Heather, Boz, Ceilia, Brown, Adam, Chikowore, Primmy, Coutts, Audrey, Coyle, Judy, Cullum, Louise, Das, Sukamal, Day, Nicky, Donnelly, Lorna, Duncan, Esther, Finernan, Paul, Fourman, Max Head, Furlong, Anita, Furniss, James, Gallagher, Bernadette, Gilchrist, Tammy, Golightly, Ailsa, Hafezi, Katarzyna, Hamilton, Debbie, Hendry, Ross, Kearns, Naomi, Law, Dawn, Law, Rachel, Law, Sarah, Lidstone-Scott, Rebecca, Lauder, Christen, Macgillivray, Louise, Maclean, Alan, Mal, Hanning, McCafferty, Sarah, Mcmaster, Ellie, Meikle, Jen, Moore, Shona C., Murphy, Sheena, Mybaya, Hellen, Oosthuyzen, Wilna, Zheng, Chenqing, Chen, Jiantao, Paterson, Trevor, Tucker, Petra, Schon, Katherine, Stenhouse, Andrew, Das, Mihaela, Swets, Maaike, Szoor-McElhinney, Helen, Taneski, Filip, Turtle, Lance, Wackett, Tony, Ward, Mairi, Weaver, Jane, Wrobel, Nicola, Rakitko, Alexander, Ilinsky, Valery, Yermakovich, Danat, Popov, Iaroslav, Chernitsov, Alexander, Kovalenko, Elena, Vergasova, Ekaterina, Prokhorov, Alexandr, Krasnenko, Anna, Plotnikov, Nikolay, Stetsenko, Ivan, Kim, Anna, Cirulli, Elizabeth T., Schiabor Barrett, Kelly M., Bolze, Alexandre, White, Simon, Washington, Nicole L., Lu, James T., Riffle, Stephen, Tanudjaja, Francisco, Wang, Xueqing, Ramirez, Jimmy M., Leonetti, Nicole, Sandoval, Efren, Neveux, Iva, Dabe, Shaun, Grzymski, Joseph J., Joshi, Madhvi N., Dixit, Raghav D., Shah, Pranay K., Upadhyay, Kamlesh J., Chuhan, Naresh T., Desai, Kairavi J., Shah, Meenakshi R., Modi, Bhavesh, Joshi, Chaitanya G., Pandit, Ramesh J., Singh, Indra, Ansari, Afzal I., Raval, Janvi N., Patel, Zarna Z., Moreno-Estrada, Andres, Vázquez-Pérez, Joel Armando, Castillejos-López, Manuel, Aquino-Gálvez, Arnoldo, Shamah-Levy, Teresa, Ávila-Arcos, María C., Luna, María Teresa Tusié, Hidalgo-Miranda, Alfredo, Barberena-Jonas, Carmina, Quinto-Cortés, Consuelo D., Ávila-Arcos, Marco Antonio, Huerta-Chagoya, Alicia, García-García, Lourdes, Barnetche, Jesús Martinez, Alpuche-Aranda, Celia, Rivera, Juan A., Gutiérrez, Tonatiuh Barrientos, Ochoa-Guzmán, Ana, Ordoñez-Sánchez, Maria Luisa, Segura-Kato, Yayoi, Herrera-Montalvo, Luis Alonso, Mendoza-Vargas, Alfredo, Reyes-Grajeda, Juan Pablo, Cruz-Cruz, Alonso D., Velázquez-Cruz, Rafael, Torres-Espíndola, Luz María, Sierra-Vargas, Martha Patricia, Camarena, Angel, Ruiz, Víctor, Chávez-Alderete, Jaime, Jaime-Capetillo, María Esther, Guadarrama-Pérez, Cristóbal, Zúñiga-Ramos, Joaquin, Olivera-Ramírez, Alejandra, Martínez, Miguel Angel López, Serna-Muñoz, Ricardo, Garmendia, Adriana, Namkoong, Ho, Okada, Yukinori, Imoto, Seiya, Katayama, Kazuhiko, Fukunaga, Koichi, Kitagawa, Yuko, Sato, Toshiro, Hasegawa, Naoki, Kumanogoh, Atsushi, Kimura, Akinori, Ai, Masumi, Tokunaga, Katsushi, Kanai, Takanori, Miyano, Satoru, Ogawa, Seishi, Edahiro, Ryuya, Sonehara, Kyuto, Shirai, Yuya, Ishii, Makoto, Kabata, Hiroki, Masaki, Katsunori, Kamata, Hirofumi, Ikemura, Shinnosuke, Chubachi, Shotaro, Okamori, Satoshi, Terai, Hideki, Tanaka, Hiromu, Morita, Atsuho, Lee, Ho, Asakura, Takanori, Sasaki, Junichi, Morisaki, Hiroshi, Uwamino, Yoshifumi, Nanki, Kosaku, Mikami, Yohei, Tomono, Kazunori, Kato, Kazuto, Matsuda, Fumihiko, Takahashi, Meiko, Hizawa, Nobuyuki, Takeda, Yoshito, Hirata, Haruhiko, Shiroyama, Takayuki, Miyawaki, Satoru, Suzuki, Ken, Maeda, Yuichi, Nii, Takuro, Noda, Yoshimi, Niitsu, Takayuki, Adachi, Yuichi, Enomoto, Takatoshi, Amiya, Saori, Hara, Reina, Takahashi, Kunihiko, Anzai, Tatsuhiko, Hasegawa, Takanori, Ito, Satoshi, Koike, Ryuji, Endo, Akifumi, Uchimura, Yuji, Miyazaki, Yasunari, Honda, Takayuki, Tateishi, Tomoya, Tohda, Shuji, Ichimura, Naoya, Sonobe, Kazunari, Sassa, Chihiro, Nakajima, Jun, Nannya, Yasuhito, Omae, Yosuke, Takahashi, Kazuhisa, Harada, Norihiro, Hiki, Makoto, Takagi, Haruhi, Nakamura, Ai, Tagaya, Etsuko, Kawana, Masatoshi, Arimura, Ken, Ishiguro, Takashi, Takayanagi, Noboru, Isono, Taisuke, Takaku, Yotaro, Takano, Kenji, Anan, Ryusuke, Nakajima, Yukiko, Nakano, Yasushi, Nishio, Kazumi, Ueda, Soichiro, Hayashi, Reina, Tateno, Hiroki, Hase, Isano, Yoshida, Shuichi, Suzuki, Shoji, Mitamura, Keiko, Saito, Fumitake, Ueda, Tetsuya, Azuma, Masanori, Nagasaki, Tadao, Yasui, Yoshinori, Hasegawa, Yoshinori, Mutoh, Yoshikazu, Yoshiyama, Takashi, Shoko, Tomohisa, Kojima, Mitsuaki, Adachi, Tomohiro, Ishikawa, Motonao, Takahashi, Kenichiro, Watanabe, Kazuyoshi, Manabe, Tadashi, Ito, Fumimaro, Fukui, Takahiro, Funatsu, Yohei, Koh, Hidefumi, Hirai, Yoshihiro, Kawashima, Hidetoshi, Narita, Atsuya, Niwa, Kazuki, Sekikawa, Yoshiyuki, Saito, Fukuki, Yoshiya, Kazuhisa, Yoshihara, Tomoyuki, Suzuki, Yusuke, Nakayama, Sohei, Masuzawa, Keita, Nishi, Koichi, Nishitsuji, Masaru, Tani, Maiko, Inoue, Takashi, Hirano, Toshiyuki, Kobayashi, Keigo, Miyazawa, Naoki, Kimura, Yasuhiro, Sado, Reiko, Ogura, Takashi, Kitamura, Hideya, Murohashi, Kota, Nakachi, Ichiro, Baba, Rie, Arai, Daisuke, Fuke, Satoshi, Saito, Hiroshi, Kuwahara, Naota, Fujiwara, Akiko, Okada, Takenori, Baba, Tomoya, Noda, Junya, Mashimo, Shuko, Yagi, Kazuma, Shiomi, Tetsuya, Hashiguchi, Mizuha, Odani, Toshio, Mochimaru, Takao, Oyamada, Yoshitaka, Mori, Nobuaki, Izumi, Namiki, Nagata, Kaoru, Taki, Reiko, Murakami, Koji, Yamada, Mitsuhiro, Sugiura, Hisatoshi, Hayashi, Kentaro, Shimizu, Tetsuo, Gon, Yasuhiro, Fujitani, Shigeki, Tsuchida, Tomoya, Yoshida, Toru, Kagaya, Takashi, Kita, Toshiyuki, Sakagami, Satoru, Kimizuka, Yoshifumi, Kawana, Akihiko, Nakamura, Yoshihiko, Ishikura, Hiroyasu, Takata, Tohru, Kikuchi, Takahide, Taniyama, Daisuke, Nakamura, Morio, Kodama, Nobuhiro, Kaneyama, Yasunari, Maeda, Shunsuke, Nagasaki, Yoji, Okamoto, Masaki, Ishihara, Sayoko, Ito, Akihiro, Chihara, Yusuke, Takeuchi, Mayumi, Onoi, Keisuke, Hashimoto, Naozumi, Wakahara, Keiko, Ando, Akira, Masuda, Makoto, Wakabayashi, Aya, Watanabe, Hiroki, Sageshima, Hisako, Nakada, Taka-Aki, Abe, Ryuzo, Shimada, Tadanaga, Kawamura, Kodai, Ichikado, Kazuya, Nishiyama, Kenta, Yamasaki, Masaki, Hashimoto, Satoru, Kusaka, Yu, Ohba, Takehiko, Isogai, Susumu, Takada, Minoru, Kanda, Hidenori, Komase, Yuko, Sano, Fumiaki, Asano, Koichiro, Oguma, Tsuyoshi, Harada, Masahiro, Takahashi, Takeshi, Shibusawa, Takayuki, Abe, Shinji, Kono, Yuta, Togashi, Yuki, Izumo, Takehiro, Inomata, Minoru, Awano, Nobuyasu, Ogawa, Shinichi, Ogata, Tomouki, Ishihara, Shoichiro, Kanehiro, Arihiko, Ozaki, Shinji, Fuchimoto, Yasuko, Kitagawa, Yuichiro, Yoshida, Shozo, Ogura, Shinji, Nishiyama, Kei, Yoshida, Kousuke, Beppu, Satoru, Fukuyama, Satoru, Eriguchi, Yoshihiro, Yonekawa, Akiko, Inoue, Yoshiaki, Yamagata, Kunihiro, Chiba, Shigeru, Narumoto, Osamu, Nagai, Hideaki, Ooshima, Nobuharu, Motegi, Mitsuru, Sagara, Hironori, Tanaka, Akihiko, Ohta, Shin, Shibata, Yoko, Tanino, Yoshinori, Sato, Yuki, Yamada, Yuichiro, Hashino, Takuya, Shinoki, Masato, Iwagoe, Hajime, Imamura, Tomonori, Umeda, Akira, Shimada, Hisato, Endo, Mayu, Hayashi, Shinichi, Takahashi, Mai, Nakano, Shigefumi, Yatomi, Masakiyo, Maeno, Toshitaka, Ishii, Tomoo, Utsugi, Mitsuyoshi, Ono, Akihiro, Kanaoka, Kensuke, Ihara, Shoichi, Komuta, Kiyoshi, Nishida, Nao, Kawai, Yosuke, Sugiyama, Masaya, Alawneh, Laith M., Maswadeh, Kinda B., Alsoub, Fatima S., AlRawashdeh, Tala J., Esawi, Ezaldeen, Abu Alragheb, Bayan O., Maswadeh, Ahmad B., Al-Kadash, Abdulfattah, Al-Ani, Abdallah, Alsafadi, Dana B., Shahin, Mohammad A., Qtaish, Nuseibah Al, Alawneh, Fade M., Abulail, Joseph A., Zhlawi, Hadi J., Alhousani, Tasneem N., Alzuraiqi, Mohammad R., Al-Ja’afreh, Mohammad M., Allouzy, Sara K., ALjalamdeh, Mothafer, Mansour, Tareq M., Alamer, Lina M., Issa, Ali Banni, Bani younis, Fatima M., Hawari, Feras I., Hayajneh, Wail A., Obeidat, Nathir M., Ahram, Mamoun, Zhlawi, Moh’d Wahib J., Alshaer, Walhan, Al-Kasasbeh, Malak M., Naffa, Randa G., Ismail, Mohammad A., Abdullah, Mohammed S., Ismail, Said I., Obeidat, Ma’en, Hernández Cordero, Ana I., Sin, Don D., Bossé, Yohan, Joubert, Philippe, Hao, Ke, Nickle, David, Timens, Wim, van den Berge, Maarten, Feng, Yen-Chen Anne, Mercader, Josep, Weiss, Scott T., Karlson, Elizabeth W., Smoller, Jordan W., Murphy, Shawn N., Meigs, James B., Woolley, Ann E., Green, Robert C., Mandla, Ravi, Schroeder, Philip, Perez, Emma F., Lee, Seung Hyuk T., Flores-Silva, Fernando Daniel, Chiquete, Erwin, Cantú-Brito, Carlos, Sifuentes-Osornio, José, de León-Garduño, Alfredo Ponce, Román-Montes, Carla Marina, Chávez-Manzanera, Emma, Velasco, Donaji Gómez, Martagón-Rosado, Alexandro, Cruz-Bautista, Ivette, Gómez-Pérez, Francisco Javier, Díaz-Olavarrieta, Claudia, Valdés, Paloma Almeda, Muñóz-Hernández, Linda Liliana, Mehta, Roopa Pravin, Elías-López, Daniel, Tusié-Luna, Teresa, Pajukanta, Päivi, Sukhatme, Mihir G., Moreno-Macías, Hortensia, Ruth, Johnson, González-Behn-Eschenburg, Sebastián, García-Grimshaw, Miguel, Guillen-Pineda, Luz Elizabeth, de los Ángeles Vargas-Martínez, María, Rodríguez, Maribel, Rodríguez-Guillén, Rosario, Ordoñez, María Luisa, Rajme-López, Sandra, González-Lara, María Fernanda, Luna-Moreno, Dalia, de Jesús Suárez López, Jannet, Guillén-Quintero, Daniela Mariel, Vega, Juan, Duran-Coyote, Salvador, Guerra-García, María Teresa, Durán-Gómez, Michelle, Vigueras-Hernández, Alma, Ramírez-Jiménez, Marco Eduardo, Grajeda-González, Samara Lissete, Ramos-Galicia, Enrique Manuel, Ramírez-Carrillo, Martha Fernanda, Fernandez-Ruiz, Juan, Chirino-Pérez, Amanda, Romero-Molina, Ángel Omar, Zavaleta, David Alejandro Fuentes, Jaramillo, María Andrea Mac Donald, López, Katia Jarely Prieto, Incontri-Abraham, Diego, Rosado, Wendy Natalia, Catalán, María Alonso, Aguilar, Sonia Evelyn Vital, Zamudio, Ileana Paola Montero, Ruíz-Ruíz, Eduardo, de Jesús Carrera García, Kevin, Guerrero, Cristina Villarreal, Martínez, Ana Isabel Rodríguez, Moscoso-Sánchez, Rogelio, del Consuelo Rodríguez Mancilla, María, Villa, Antonio, Luna-Ramírez, Samuel Alejandro, Hernández-Hernández, Sergio, Frias, Erika, Campos, Alejandro, Morales-Sosa, Paola Alessandra, Toxqui-Merchant, Luis Enrique, García, Karla, Pasaniuc, Bogdan, Butte, Manish J., Geschwind, Daniel H., Aguilar-Salinas, Carlos A., Heidecker, Bettina, Kurth, Florian, Sander, Leif E., Skurk, Carsten, Landmesser, Ulf, Karadeniz, Zehra, Wang, Xiaomin, Poller, Wolfgang, Suwalski, Phillip, Ripke, Stephan, Braun, Alice, Kraft, Julia, Mayer, Alena, Lippert, Lena J., Helbig, Elisa T., Thibeault, Charlotte, Awasthi, Swapnil, Mbarek, Hamdi, Saad, Chadi, Al-Sarraj, Yaser, Badji, Radja Messai, Al-Muftah, Wadha, Thani, Asma Al, Afifi, Nahla, Sadiq, Fouzia, Khan, Mohammad I., Bhutta, Muhammad J., Khan, Hania, Khan, Madeeha, Ain, Quratul, Junaid, Ayesha, Khan, Ejaz A., Sypniewski, Mateusz, Lejman, Adrian, Zawadzki, Paweł, Sztromwasser, Paweł, Król, Zbigniew, Dobosz, Paula, Stojak, Joanna, Flores, Carlos, Carracedo, Ángel, Aguilar, Carlos, Arranz, María J., Baptista-Rosas, Raúl C., Bezerra, Joao F., Bezerra, Marcos A. C., Brugada, Ramón, Bustos, Matilde, Castano, Luis, Conde-Vicente, Rosa, Cordero-Lorenzana, M. Lourdes, De Martino-Rodríguez, Alba, Domínguez-Garrido, Elena, Fariñas, María Carmen, Gil-Fournier, Belén, Herrero, María José, Lattig, María Claudia, Martín-López, Caridad, Martín, Vicente, Martinez-Nieto, Oscar, Martinez-Lopez, Iciar, Mazzeu, Juliana F., Macías, Eleuterio Merayo, Cuerda, Victor Moreno, Silbiger, Vivian N., Oliveira, Silviene F., Parellada, Mara, Santos, Ney P. C., Pérez-Matute, Patricia, Perez, Patricia, Perucho, Teresa, Porras-Hurtado, Gloria L., Pujol, Aurora, Fernández-Rodríguez, Amanda, Jimenez-Sousa, María A., Rodríguez-Ruiz, Emilio, Rodriguez-Artalejo, Fernando, Rodriguez-Garcia, José A., Ruiz-Cabello, Francisco, Soria, José Manuel, Tamayo, Eduardo, Teper, Alejandro, Torres-Tobar, Lilian, Urioste, Miguel, Yáñez, Zuleima, Zarate, Ruth, Guillen-Navarro, Encarna, Ayuso, Carmen, González-Neira, Anna, Riancho, José A., Rojas-Martinez, Augusto, Lapunzina, Pablo, Cruz, Raquel, Diz-de Almeida, Silvia, Ceballos, Francisco C., Lorenzo-Salazar, José M., González-Montelongo, Rafaela, Quintela, Inés, Pita, Guillermo, Gago-Domínguez, Manuela, Porras, Marta Sevilla, Tenorio-Castaño, Jair Antonio, Nevado, Julian, Aguado, Jose María, Aguilera-Albesa, Sergio, Almadana, Virginia, Almoguera, Berta, Alvarez, Nuria, Andreu-Bernabeu, Álvaro, Arango, Celso, Artiga, Maria-Jesus, Barreda-Sánchez, María, Belhassen-Garcia, Moncef, Boix-Palop, Lucía, Brion, María, Carbonell, Cristina, Castelao, Jose E., Cortes-Sanchez, Jose L., Corton, Marta, Darnaude, M. Teresa, del Campo-Pérez, Victor, de Bustamante, Aranzazu Diaz, Luchessi, Andre D., Eiros, Rocío, Sanabria, Gladys Mercedes Estigarribia, Fernández-Robelo, Uxía, Fernández-Villa, Tania, Gómez-Arrue, Javier, Álvarez, Beatriz González, de Quirós, Fernan Gonzalez Bernaldo, González-Peñas, Javier, Gutiérrez-Bautista, Juan F., Herrero-Gonzalez, Antonio, Borja, Anabel Liger, Lopez-Rodriguez, Rosario, Mancebo, Esther, Martinez-Resendez, Michel F., Martinez-Perez, Angel, Minguez, Pablo, Ortega-Paino, Eva, Paz-Artal, Estela, Pérez-Tomás, M. Elena, Pinsach-Abuin, Mel·lina, Pompa-Mera, Ericka N., León, Soraya Ramiro, Resino, Salvador, Fernandes, Marianne R., Ruiz-Hornillos, Javier, Ryan, Pablo, Souto, Juan Carlos, Tamayo-Velasco, Alvaro, Taracido-Fernandez, Juan Carlos, Valencia-Ramos, Juan, de Heredia, Miguel López, Pedersen, Ole B., Erikstrup, Christian, Ostrowski, Sisse R., Stefansson, Kari, Mikkelsen, Susan, Sørensen, Erik, Burgos, Celia, Andersen, Steffen, Brugdorf, Kristoffer, Hansen, Thomas F., Hjalgrim, Henrik, Jemec, Gregor B., Nyegaard, Mette, Werge, Thomas, Johansson, Pär I., Didriksen, Maria, Schwinn, Michael, Jacobsen, Rikke L., Hindhede, Lotte, Rostgaard, Klaus, Gudbjartsson, Daniel, Stefánsson, Hreinn, Þorsteinsdóttir, Unnur, Nielsen, Kaspar R., Bruun, Mie Topholm, Dinh, Khoa M., Larsen, Margit A. H., Sækmose, Susanne G., Zeberg, Hugo, Nkambul, Lindo, Frithiof, Robert, Hultström, Michael, Lipcsey, Miklos, Tardif, Nicolas, Rooyackers, Olav, Grip, Jonathan, Maricic, Tomislav, Heid, Iris M., Wagner, Ralf, Überla, Klaus, Winkler, Thomas W., Wiegrebe, Simon, Gorski, Mathias, Stark, Klaus J., Peterhoff, David, Einhauser, Sebastian, Niller, Hans-Helmut, Beileke, Stephanie, Johnson, Ruth, Freimer, Nelson, Ding, Yi, Chiu, Alec, Chang, Timothy S., Boutros, Paul, Karczewski, Konrad J., Martin, Alicia R., Wilson, Daniel J., Spencer, Chris C. A., Crook, Derrick W., Wyllie, David H., O’Connell, Anne Marie, Atkinson, Elizabeth G., Tsuo, Kristin, Baya, Nikolas, Turley, Patrick, Gupta, Rahul, Walters, Raymond K., Palmer, Duncan S., Sarma, Gopal, Solomonson, Matthew, Cheng, Nathan, Lu, Wenhan, Churchhouse, Claire, Goldstein, Jacqueline I., King, Daniel, Zhou, Wei, Seed, Cotton, Daly, Mark J., Finucane, Hilary, Bryant, Sam, Satterstrom, F. Kyle, Band, Gavin, Earle, Sarah G., Lin, Shang-Kuan, Arning, Nicolas, Koelling, Nils, Armstrong, Jacob, Rudkin, Justine K., Callier, Shawneequa, Cusick, Caroline, Fernandez-Cadenas, Israel, Planas, Anna M., Perez-Tur, Jordi, Llucià-Carol, Laia, Cullell, Natalia, Muiño, Elena, Cárcel-Márquez, Jara, DeDiego, Marta L., Iglesias, Lara Lloret, Soriano, Alex, Rico, Veronica, Agüero, Daiana, Bedini, Josep L., Lozano, Francisco, Domingo, Carlos, Robles, Veronica, Ruiz-Jaén, Francisca, Márquez, Leonardo, Gomez, Juan, Coto, Eliecer, Albaiceta, Guillermo M., García-Clemente, Marta, Dalmau, David, Arranz, Maria J., Dietl, Beatriz, Serra-Llovich, Alex, Soler-Palacin, Pere, Colobran, Roger, Martin-Nalda, Andrea, Parra-Martínez, Alba, Bernardo, David, Rojo, Silvia, Fiz-López, Aida, Arribas-Rodriguez, Elisa, Cal-Sabater, Paloma, Segura, Tomás, González-Villar, Esther, Serrano-Heras, Gemma, Martí-Fàbregas, Joan, Jiménez-Xarrié, Elena, de Felipe Mimbrera, Alicia, Masjuan, Jaime, García-Madrona, Sebastian, Domínguez-Mayoral, Anna, Villalonga, Joan Montaner, and Menéndez-Valladares, Paloma
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- 2023
27. Genetic counselling and testing in pulmonary arterial hypertension:a consensus statement on behalf of the International Consortium for Genetic Studies in PAH
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Eichstaedt, Christina A., Belge, Catharina, Chung, Wendy K., Gräf, Stefan, Grünig, Ekkehard, Montani, David, Quarck, Rozenn, Tenorio-Castano, Jair A., Soubrier, Florent, Trembath, Richard C., Morrell, Nicholas W., Aldred, Micheala A., Archer, Stephen L., Austin, Eric D., Badagliacca, Roberto, Balanchandar, Srimmitha, Barberà, Joan Albert, Benza, Raymond L., Berger, Rolf M.F., Bogaard, Harm Jan, Bonnet, Sébastien, Boomars, Karin A., Boucherat, Olivier, Chakinala, Murali M., Condliffe, Robin, Damico, Rachel Lynn, Delcroix, Marion, Desai, Ankit A., Doboszynska, Anna, Dooijes, Dennis, Elliott, C. Greg, Eyries, Melanie, Subías, Maria Pilar Escribano, Gall, Henning, García-Aranda, Beatriz, Ghio, Stefano, Ghofrani, Hossein Ardeschir, Hamid, Rizwan, Hassoun, Paul M., Hemnes, Anna R., Hinderhofer, Katrin, Houweling, Arjan C., Howard, Luke S., Humbert, Marc, Kiely, David G., Kovacs, Gabor, Langleben, David, Lapunzina, Pablo, Lawrie, Allan, Loyd, Jim E., Eichstaedt, Christina A., Belge, Catharina, Chung, Wendy K., Gräf, Stefan, Grünig, Ekkehard, Montani, David, Quarck, Rozenn, Tenorio-Castano, Jair A., Soubrier, Florent, Trembath, Richard C., Morrell, Nicholas W., Aldred, Micheala A., Archer, Stephen L., Austin, Eric D., Badagliacca, Roberto, Balanchandar, Srimmitha, Barberà, Joan Albert, Benza, Raymond L., Berger, Rolf M.F., Bogaard, Harm Jan, Bonnet, Sébastien, Boomars, Karin A., Boucherat, Olivier, Chakinala, Murali M., Condliffe, Robin, Damico, Rachel Lynn, Delcroix, Marion, Desai, Ankit A., Doboszynska, Anna, Dooijes, Dennis, Elliott, C. Greg, Eyries, Melanie, Subías, Maria Pilar Escribano, Gall, Henning, García-Aranda, Beatriz, Ghio, Stefano, Ghofrani, Hossein Ardeschir, Hamid, Rizwan, Hassoun, Paul M., Hemnes, Anna R., Hinderhofer, Katrin, Houweling, Arjan C., Howard, Luke S., Humbert, Marc, Kiely, David G., Kovacs, Gabor, Langleben, David, Lapunzina, Pablo, Lawrie, Allan, and Loyd, Jim E.
- Abstract
Pulmonary arterial hypertension (PAH) is a rare disease that can be caused by (likely) pathogenic germline genomic variants. In addition to the most prevalent disease gene, BMPR2 (bone morphogenetic protein receptor 2), several genes, some belonging to distinct functional classes, are also now known to predispose to the development of PAH. As a consequence, specialist and non-specialist clinicians and healthcare professionals are increasingly faced with a range of questions regarding the need for, approaches to and benefits/risks of genetic testing for PAH patients and/or related family members. We provide a consensus-based approach to recommendations for genetic counselling and assessment of current best practice for disease gene testing. We provide a framework and the type of information to be provided to patients and relatives through the process of genetic counselling, and describe the presently known disease causal genes to be analysed. Benefits of including molecular genetic testing within the management protocol of patients with PAH include the identification of individuals misclassified by other diagnostic approaches, the optimisation of phenotypic characterisation for aggregation of outcome data, including in clinical trials, and importantly through cascade screening, the detection of healthy causal variant carriers, to whom regular assessment should be offered.
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- 2023
28. Health and population effects of rare gene knockouts in adult humans with related parents
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Narasimhan, Vagheesh M., Hunt, Karen A., Mason, Dan, Baker, Christopher L., Karczewski, Konrad J., Barnes, Michael R., Barnett, Anthony H., Bates, Chris, Bellary, Srikanth, Bockett, Nicholas A., Giorda, Kristina, Griffiths, Christopher J., Hemingway, Harry, Jia, Zhilong, Kelly, M. Ann, Khawaja, Hajrah A., Lek, Monkol, McCarthy, Shane, McEachan, Rosie, O'Donnell-Luria, Anne, Paigen, Kenneth, Parisinos, Constantinos A., Sheridan, Eamonn, Southgate, Laura, Tee, Louise, Thomas, Mark, Xue, Yali, Schnall-Levin, Michael, Petkov, Petko M., Tyler-Smith, Chris, Maher, Eamonn R., Trembath, Richard C., MacArthur, Daniel G., Wright, John, Durbin, Richard, and van Heel, David A.
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- 2016
29. Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease
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Zhou, Wei, Kanai, Masahiro, Wu, Kuan-Han H, Rasheed, Humaira, Tsuo, Kristin, Hirbo, Jibril B, Wang, Ying, Bhattacharya, Arjun, Zhao, Huiling, Namba, Shinichi, Surakka, Ida, Wolford, Brooke N, Lo Faro, Valeria, Lopera-Maya, Esteban A, Läll, Kristi, Favé, Marie-Julie, Partanen, Juulia J, Chapman, Sinéad B, Karjalainen, Juha, Kurki, Mitja, Maasha, Mutaamba, Brumpton, Ben M, Chavan, Sameer, Chen, Tzu-Ting, Daya, Michelle, Ding, Yi, Feng, Yen-Chen A, Guare, Lindsay A, Gignoux, Christopher R, Graham, Sarah E, Hornsby, Whitney E, Ingold, Nathan, Ismail, Said I, Johnson, Ruth, Laisk, Triin, Lin, Kuang, Lv, Jun, Millwood, Iona Y, Moreno-Grau, Sonia, Nam, Kisung, Palta, Priit, Pandit, Anita, Preuss, Michael H, Saad, Chadi, Setia-Verma, Shefali, Thorsteinsdottir, Unnur, Uzunovic, Jasmina, Verma, Anurag, Zawistowski, Matthew, Zhong, Xue, Afifi, Nahla, Al-Dabhani, Kawthar M, Al Thani, Asma, Bradford, Yuki, Campbell, Archie, Crooks, Kristy, De Bock, Geertruida H, Damrauer, Scott M, Douville, Nicholas J, Finer, Sarah, Fritsche, Lars G, Fthenou, Eleni, Gonzalez-Arroyo, Gilberto, Griffiths, Christopher J, Guo, Yu, Hunt, Karen A, Ioannidis, Alexander, Jansonius, Nomdo M, Konuma, Takahiro, Lee, Ming Ta Michael, Lopez-Pineda, Arturo, Matsuda, Yuta, Marioni, Riccardo E, Moatamed, Babak, Nava-Aguilar, Marco A, Numakura, Kensuke, Patil, Snehal, Rafaels, Nicholas, Richmond, Anne, Rojas-Muñoz, Agustin, Shortt, Jonathan A, Straub, Peter, Tao, Ran, Vanderwerff, Brett, Vernekar, Manvi, Veturi, Yogasudha, Barnes, Kathleen C, Boezen, Marike, Chen, Zhengming, Chen, Chia-Yen, Cho, Judy, Smith, George Davey, Finucane, Hilary K, Franke, Lude, Gamazon, Eric R, Ganna, Andrea, Gaunt, Tom R, Ge, Tian, Huang, Hailiang, Huffman, Jennifer, Katsanis, Nicholas, Koskela, Jukka T, Lajonchere, Clara, Law, Matthew H, Li, Liming, Lindgren, Cecilia M, Loos, Ruth JF, MacGregor, Stuart, Matsuda, Koichi, Olsen, Catherine M, Porteous, David J, Shavit, Jordan A, Snieder, Harold, Takano, Tomohiro, Trembath, Richard C, Vonk, Judith M, Whiteman, David C, Wicks, Stephen J, Wijmenga, Cisca, Wright, John, Zheng, Jie, Zhou, Xiang, Awadalla, Philip, Boehnke, Michael, Bustamante, Carlos D, Cox, Nancy J, Fatumo, Segun, Geschwind, Daniel H, Hayward, Caroline, Hveem, Kristian, Kenny, Eimear E, Lee, Seunggeun, Lin, Yen-Feng, Mbarek, Hamdi, Mägi, Reedik, Martin, Hilary C, Medland, Sarah E, Okada, Yukinori, Palotie, Aarno V, Pasaniuc, Bogdan, Rader, Daniel J, Ritchie, Marylyn D, Sanna, Serena, Smoller, Jordan W, Stefansson, Kari, Van Heel, David A, Walters, Robin G, Zöllner, Sebastian, Biobank Of The Americas, Biobank Japan Project, BioMe, BioVU, CanPath-Ontario Health Study, China Kadoorie Biobank Collaborative Group, Colorado Center For Personalized Medicine, DeCODE Genetics, Estonian Biobank, FinnGen, Generation Scotland, Genes & Health Research Team, LifeLines, Mass General Brigham Biobank, Michigan Genomics Initiative, National Biobank Of Korea, Penn Medicine BioBank, Qatar Biobank, QSkin Sun And Health Study, Taiwan Biobank, HUNT Study, UCLA ATLAS Community Health Initiative, Uganda Genome Resource, UK Biobank, Martin, Alicia R, Willer, Cristen J, Daly, Mark J, Neale, Benjamin M, Namba, Shinichi [0000-0002-7486-3146], Guare, Lindsay A [0000-0001-6988-5319], Palta, Priit [0000-0001-9320-7008], de Bock, Geertruida H [0000-0003-3104-4471], Finer, Sarah [0000-0002-2684-4653], Jansonius, Nomdo M [0000-0002-6495-6568], Rojas-Muñoz, Agustin [0000-0001-7594-0599], Gamazon, Eric R [0000-0003-4204-8734], Ganna, Andrea [0000-0002-8147-240X], Koskela, Jukka T [0000-0002-0154-7222], MacGregor, Stuart [0000-0001-6731-8142], Palotie, Aarno V [0000-0002-2527-5874], and Apollo - University of Cambridge Repository
- Subjects
biobank ,meta-analysis ,genetic association studies ,GWAS ,ancestry diversity ,phenotype harmonization - Abstract
Funder: Biogen, Biobanks facilitate genome-wide association studies (GWASs), which have mapped genomic loci across a range of human diseases and traits. However, most biobanks are primarily composed of individuals of European ancestry. We introduce the Global Biobank Meta-analysis Initiative (GBMI)-a collaborative network of 23 biobanks from 4 continents representing more than 2.2 million consented individuals with genetic data linked to electronic health records. GBMI meta-analyzes summary statistics from GWASs generated using harmonized genotypes and phenotypes from member biobanks for 14 exemplar diseases and endpoints. This strategy validates that GWASs conducted in diverse biobanks can be integrated despite heterogeneity in case definitions, recruitment strategies, and baseline characteristics. This collaborative effort improves GWAS power for diseases, benefits understudied diseases, and improves risk prediction while also enabling the nomination of disease genes and drug candidates by incorporating gene and protein expression data and providing insight into the underlying biology of human diseases and traits.
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- 2023
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30. Integrative Multiomics to Dissect the Lung Transcriptional Landscape of Pulmonary Arterial Hypertension
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Hong, Jason, primary, Wong, Brenda, additional, Rhodes, Christopher J., additional, Kurt, Zeyneb, additional, Schwantes-An, Tae-Hwi, additional, Mickler, Elizabeth A., additional, Gräf, Stefan, additional, Eyries, Mélanie, additional, Lutz, Katie A., additional, Pauciulo, Michael W., additional, Trembath, Richard C., additional, Montani, David, additional, Morrell, Nicholas W., additional, Wilkins, Martin R., additional, Nichols, William C., additional, Trégouët, David-Alexandre, additional, Aldred, Micheala A., additional, Desai, Ankit A., additional, Tuder, Rubin M., additional, Geraci, Mark W., additional, Eghbali, Mansoureh, additional, Stearman, Robert S., additional, and Yang, Xia, additional
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- 2023
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31. Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts
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Wang, Ying, primary, Namba, Shinichi, additional, Lopera, Esteban, additional, Kerminen, Sini, additional, Tsuo, Kristin, additional, Läll, Kristi, additional, Kanai, Masahiro, additional, Zhou, Wei, additional, Wu, Kuan-Han, additional, Favé, Marie-Julie, additional, Bhatta, Laxmi, additional, Awadalla, Philip, additional, Brumpton, Ben, additional, Deelen, Patrick, additional, Hveem, Kristian, additional, Lo Faro, Valeria, additional, Mägi, Reedik, additional, Murakami, Yoshinori, additional, Sanna, Serena, additional, Smoller, Jordan W., additional, Uzunovic, Jasmina, additional, Wolford, Brooke N., additional, Willer, Cristen, additional, Gamazon, Eric R., additional, Cox, Nancy J., additional, Surakka, Ida, additional, Okada, Yukinori, additional, Martin, Alicia R., additional, Hirbo, Jibril, additional, Wu, Kuan-Han H., additional, Rasheed, Humaira, additional, Hirbo, Jibril B., additional, Wang, Ying, additional, Bhattacharya, Arjun, additional, Zhao, Huiling, additional, Lopera-Maya, Esteban A., additional, Chapman, Sinéad B., additional, Karjalainen, Juha, additional, Kurki, Mitja, additional, Mutaamba, Maasha, additional, Partanen, Juulia J., additional, Brumpton, Ben M., additional, Chavan, Sameer, additional, Chen, Tzu-Ting, additional, Daya, Michelle, additional, Ding, Yi, additional, Feng, Yen-Chen A., additional, Gignoux, Christopher R., additional, Graham, Sarah E., additional, Hornsby, Whitney E., additional, Ingold, Nathan, additional, Johnson, Ruth, additional, Laisk, Triin, additional, Lin, Kuang, additional, Lv, Jun, additional, Millwood, Iona Y., additional, Palta, Priit, additional, Pandit, Anita, additional, Preuss, Michael H., additional, Thorsteinsdottir, Unnur, additional, Zawistowski, Matthew, additional, Zhong, Xue, additional, Campbell, Archie, additional, Crooks, Kristy, additional, de Bock, Geertruida H., additional, Douville, Nicholas J., additional, Finer, Sarah, additional, Fritsche, Lars G., additional, Griffiths, Christopher J., additional, Guo, Yu, additional, Hunt, Karen A., additional, Konuma, Takahiro, additional, Marioni, Riccardo E., additional, Nomdo, Jansonius, additional, Patil, Snehal, additional, Rafaels, Nicholas, additional, Richmond, Anne, additional, Shortt, Jonathan A., additional, Straub, Peter, additional, Tao, Ran, additional, Vanderwerff, Brett, additional, Barnes, Kathleen C., additional, Boezen, Marike, additional, Chen, Zhengming, additional, Chen, Chia-Yen, additional, Cho, Judy, additional, Smith, George Davey, additional, Finucane, Hilary K., additional, Franke, Lude, additional, Ganna, Andrea, additional, Gaunt, Tom R., additional, Ge, Tian, additional, Huang, Hailiang, additional, Huffman, Jennifer, additional, Koskela, Jukka T., additional, Lajonchere, Clara, additional, Law, Matthew H., additional, Li, Liming, additional, Lindgren, Cecilia M., additional, Loos, Ruth J.F., additional, MacGregor, Stuart, additional, Matsuda, Koichi, additional, Olsen, Catherine M., additional, Porteous, David J., additional, Shavit, Jordan A., additional, Snieder, Harold, additional, Trembath, Richard C., additional, Vonk, Judith M., additional, Whiteman, David, additional, Wicks, Stephen J., additional, Wijmenga, Cisca, additional, Wright, John, additional, Zheng, Jie, additional, Zhou, Xiang, additional, Boehnke, Michael, additional, Geschwind, Daniel H., additional, Hayward, Caroline, additional, Kenny, Eimear E., additional, Lin, Yen-Feng, additional, Martin, Hilary C., additional, Medland, Sarah E., additional, Palotie, Aarno V., additional, Pasaniuc, Bogdan, additional, Stefansson, Kari, additional, van Heel, David A., additional, Walters, Robin G., additional, Zöllner, Sebastian, additional, Willer, Cristen J., additional, Daly, Mark J., additional, and Neale, Benjamin M., additional
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- 2023
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32. Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne
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Petridis, Christos, Navarini, Alexander A., Dand, Nick, Saklatvala, Jake, Baudry, David, Duckworth, Michael, Allen, Michael H., Curtis, Charles J., Lee, Sang Hyuck, Burden, A. David, Layton, Alison, Bataille, Veronique, Pink, Andrew E., The Acne Genetic Study Group, Carlavan, Isabelle, Voegel, Johannes J., Spector, Timothy D., Trembath, Richard C., McGrath, John A., Smith, Catherine H., Barker, Jonathan N., and Simpson, Michael A.
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- 2018
- Full Text
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33. Integrative Multiomics to Dissect the Lung Transcriptional Landscape of Pulmonary Arterial Hypertension
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Hong, Jason, Wong, Brenda, Rhodes, Christopher J., Kurt, Zeyneb, Schwantes-An, Tae-Hwi, Mickler, Elizabeth A., Gräf, Stefan, Eyries, Mélanie, Lutz, Katie A., Pauciulo, Michael W., Trembath, Richard C., Montani, David, Morrell, Nicholas W., Wilkins, Martin R., Nichols, William C., Trégouët, David-Alexandre, Aldred, Micheala A., Desai, Ankit A., Tuder, Rubin M., Geraci, Mark W., Eghbali, Mansoureh, Stearman, Robert S., and Yang, Xia
- Subjects
Article - Abstract
Pulmonary arterial hypertension (PAH) remains an incurable and often fatal disease despite currently available therapies. Multiomics systems biology analysis can shed new light on PAH pathobiology and inform translational research efforts. Using RNA sequencing on the largest PAH lung biobank to date (96 disease and 52 control), we aim to identify gene co-expression network modules associated with PAH and potential therapeutic targets. Co-expression network analysis was performed to identify modules of co-expressed genes which were then assessed for and prioritized by importance in PAH, regulatory role, and therapeutic potential via integration with clinicopathologic data, human genome-wide association studies (GWAS) of PAH, lung Bayesian regulatory networks, single-cell RNA-sequencing data, and pharmacotranscriptomic profiles. We identified a co-expression module of 266 genes, called the pink module, which may be a response to the underlying disease process to counteract disease progression in PAH. This module was associated not only with PAH severity such as increased PVR and intimal thickness, but also with compensated PAH such as lower number of hospitalizations, WHO functional class and NT-proBNP. GWAS integration demonstrated the pink module is enriched for PAH-associated genetic variation in multiple cohorts. Regulatory network analysis revealed that BMPR2 regulates the main target of FDA-approved riociguat, GUCY1A2, in the pink module. Analysis of pathway enrichment and pink hub genes (i.e. ANTXR1 and SFRP4) suggests the pink module inhibits Wnt signaling and epithelial-mesenchymal transition. Cell type deconvolution showed the pink module correlates with higher vascular cell fractions (i.e. myofibroblasts). A pharmacotranscriptomic screen discovered ubiquitin-specific peptidases (USPs) as potential therapeutic targets to mimic the pink module signature. Our multiomics integrative study uncovered a novel gene subnetwork associated with clinicopathologic severity, genetic risk, specific vascular cell types, and new therapeutic targets in PAH. Future studies are warranted to investigate the role and therapeutic potential of the pink module and targeting USPs in PAH.
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- 2023
34. Additional file 26 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
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Kanoni, Stavroula, Graham, Sarah E., Wang, Yuxuan, Surakka, Ida, Ramdas, Shweta, Zhu, Xiang, Clarke, Shoa L., Bhatti, Konain Fatima, Vedantam, Sailaja, Winkler, Thomas W., Locke, Adam E., Marouli, Eirini, Zajac, Greg J. M., Wu, Kuan-Han H., Ntalla, Ioanna, Hui, Qin, Klarin, Derek, Hilliard, Austin T., Wang, Zeyuan, Xue, Chao, Thorleifsson, Gudmar, Helgadottir, Anna, Gudbjartsson, Daniel F., Holm, Hilma, Olafsson, Isleifur, Hwang, Mi Yeong, Han, Sohee, Akiyama, Masato, Sakaue, Saori, Terao, Chikashi, Kanai, Masahiro, Zhou, Wei, Brumpton, Ben M., Rasheed, Humaira, Havulinna, Aki S., Veturi, Yogasudha, Pacheco, Jennifer Allen, Rosenthal, Elisabeth A., Lingren, Todd, Feng, QiPing, Kullo, Iftikhar J., Narita, Akira, Takayama, Jun, Martin, Hilary C., Hunt, Karen A., Trivedi, Bhavi, Haessler, Jeffrey, Giulianini, Franco, Bradford, Yuki, Miller, Jason E., Campbell, Archie, Lin, Kuang, Millwood, Iona Y., Rasheed, Asif, Hindy, George, Faul, Jessica D., Zhao, Wei, Weir, David R., Turman, Constance, Huang, Hongyan, Graff, Mariaelisa, Choudhury, Ananyo, Sengupta, Dhriti, Mahajan, Anubha, Brown, Michael R., Zhang, Weihua, Yu, Ketian, Schmidt, Ellen M., Pandit, Anita, Gustafsson, Stefan, Yin, Xianyong, Luan, Jian’an, Zhao, Jing-Hua, Matsuda, Fumihiko, Jang, Hye-Mi, Yoon, Kyungheon, Medina-Gomez, Carolina, Pitsillides, Achilleas, Hottenga, Jouke Jan, Wood, Andrew R., Ji, Yingji, Gao, Zishan, Haworth, Simon, Yousri, Noha A., Mitchell, Ruth E., Chai, Jin Fang, Aadahl, Mette, Bjerregaard, Anne A., Yao, Jie, Manichaikul, Ani, Hwu, Chii-Min, Hung, Yi-Jen, Warren, Helen R., Ramirez, Julia, Bork-Jensen, Jette, Kårhus, Line L., Goel, Anuj, Sabater-Lleal, Maria, Noordam, Raymond, Mauro, Pala, Matteo, Floris, McDaid, Aaron F., Marques-Vidal, Pedro, Wielscher, Matthias, Trompet, Stella, Sattar, Naveed, Møllehave, Line T., Munz, Matthias, Zeng, Lingyao, Huang, Jianfeng, Yang, Bin, Poveda, Alaitz, Kurbasic, Azra, Lamina, Claudia, Forer, Lukas, Scholz, Markus, Galesloot, Tessel E., Bradfield, Jonathan P., Ruotsalainen, Sanni E., Daw, EWarwick, Zmuda, Joseph M., Mitchell, Jonathan S., Fuchsberger, Christian, Christensen, Henry, Brody, Jennifer A., Vazquez-Moreno, Miguel, Feitosa, Mary F., Wojczynski, Mary K., Wang, Zhe, Preuss, Michael H., Mangino, Massimo, Christofidou, Paraskevi, Verweij, Niek, Benjamins, Jan W., Engmann, Jorgen, Tsao, Noah L., Verma, Anurag, Slieker, Roderick C., Lo, Ken Sin, Zilhao, Nuno R., Le, Phuong, Kleber, Marcus E., Delgado, Graciela E., Huo, Shaofeng, Ikeda, Daisuke D., Iha, Hiroyuki, Yang, Jian, Liu, Jun, Demirkan, Ayşe, Leonard, Hampton L., Marten, Jonathan, Frank, Mirjam, Schmidt, Börge, Smyth, Laura J., Cañadas-Garre, Marisa, Wang, Chaolong, Nakatochi, Masahiro, Wong, Andrew, Hutri-Kähönen, Nina, Sim, Xueling, Xia, Rui, Huerta-Chagoya, Alicia, Fernandez-Lopez, Juan Carlos, Lyssenko, Valeriya, Nongmaithem, Suraj S., Bayyana, Swati, Stringham, Heather M., Irvin, Marguerite R., Oldmeadow, Christopher, Kim, Han-Na, Ryu, Seungho, Timmers, Paul R. H. J., Arbeeva, Liubov, Dorajoo, Rajkumar, Lange, Leslie A., Prasad, Gauri, Lorés-Motta, Laura, Pauper, Marc, Long, Jirong, Li, Xiaohui, Theusch, Elizabeth, Takeuchi, Fumihiko, Spracklen, Cassandra N., Loukola, Anu, Bollepalli, Sailalitha, Warner, Sophie C., Wang, Ya Xing, Wei, Wen B., Nutile, Teresa, Ruggiero, Daniela, Sung, Yun Ju, Chen, Shufeng, Liu, Fangchao, Yang, Jingyun, Kentistou, Katherine A., Banas, Bernhard, Nardone, Giuseppe Giovanni, Meidtner, Karina, Bielak, Lawrence F., Smith, Jennifer A., Hebbar, Prashantha, Farmaki, Aliki-Eleni, Hofer, Edith, Lin, Maoxuan, Concas, Maria Pina, Vaccargiu, Simona, van der Most, Peter J., Pitkänen, Niina, Cade, Brian E., van der Laan, Sander W., Chitrala, Kumaraswamy Naidu, Weiss, Stefan, Bentley, Amy R., Doumatey, Ayo P., Adeyemo, Adebowale A., Lee, Jong Young, Petersen, Eva R. B., Nielsen, Aneta A., Choi, Hyeok Sun, Nethander, Maria, Freitag-Wolf, Sandra, Southam, Lorraine, Rayner, Nigel W., Wang, Carol A., Lin, Shih-Yi, Wang, Jun-Sing, Couture, Christian, Lyytikäinen, Leo-Pekka, Nikus, Kjell, Cuellar-Partida, Gabriel, Vestergaard, Henrik, Hidalgo, Bertha, Giannakopoulou, Olga, Cai, Qiuyin, Obura, Morgan O., van Setten, Jessica, Li, Xiaoyin, Liang, Jingjing, Tang, Hua, Terzikhan, Natalie, Shin, Jae Hun, Jackson, Rebecca D., Reiner, Alexander P., Martin, Lisa Warsinger, Chen, Zhengming, Li, Liming, Kawaguchi, Takahisa, Thiery, Joachim, Bis, Joshua C., Launer, Lenore J., Li, Huaixing, Nalls, Mike A., Raitakari, Olli T., Ichihara, Sahoko, Wild, Sarah H., Nelson, Christopher P., Campbell, Harry, Jäger, Susanne, Nabika, Toru, Al-Mulla, Fahd, Niinikoski, Harri, Braund, Peter S., Kolcic, Ivana, Kovacs, Peter, Giardoglou, Tota, Katsuya, Tomohiro, de Kleijn, Dominique, de Borst, Gert J., Kim, Eung Kweon, Adams, Hieab H. H., Ikram, M. Arfan, Zhu, Xiaofeng, Asselbergs, Folkert W., Kraaijeveld, Adriaan O., Beulens, Joline W. J., Shu, Xiao-Ou, Rallidis, Loukianos S., Pedersen, Oluf, Hansen, Torben, Mitchell, Paul, Hewitt, Alex W., Kähönen, Mika, Pérusse, Louis, Bouchard, Claude, Tönjes, Anke, Chen, Yii-Der Ida, Pennell, Craig E., Mori, Trevor A., Lieb, Wolfgang, Franke, Andre, Ohlsson, Claes, Mellström, Dan, Cho, Yoon Shin, Lee, Hyejin, Yuan, Jian-Min, Koh, Woon-Puay, Rhee, Sang Youl, Woo, Jeong-Taek, Heid, Iris M., Stark, Klaus J., Zimmermann, Martina E., Völzke, Henry, Homuth, Georg, Evans, Michele K., Zonderman, Alan B., Polasek, Ozren, Pasterkamp, Gerard, Hoefer, Imo E., Redline, Susan, Pahkala, Katja, Oldehinkel, Albertine J., Snieder, Harold, Biino, Ginevra, Schmidt, Reinhold, Schmidt, Helena, Bandinelli, Stefania, Dedoussis, George, Thanaraj, Thangavel Alphonse, Kardia, Sharon L. R., Peyser, Patricia A., Kato, Norihiro, Schulze, Matthias B., Girotto, Giorgia, Böger, Carsten A., Jung, Bettina, Joshi, Peter K., Bennett, David A., De Jager, Philip L., Lu, Xiangfeng, Mamakou, Vasiliki, Brown, Morris, Caulfield, Mark J., Munroe, Patricia B., Guo, Xiuqing, Ciullo, Marina, Jonas, Jost B., Samani, Nilesh J., Kaprio, Jaakko, Pajukanta, Päivi, Tusié-Luna, Teresa, Aguilar-Salinas, Carlos A., Adair, Linda S., Bechayda, Sonny Augustin, de Silva, H. Janaka, Wickremasinghe, Ananda R., Krauss, Ronald M., Wu, Jer-Yuarn, Zheng, Wei, Hollander, Anneke Iden, Bharadwaj, Dwaipayan, Correa, Adolfo, Wilson, James G., Lind, Lars, Heng, Chew-Kiat, Nelson, Amanda E., Golightly, Yvonne M., Wilson, James F., Penninx, Brenda, Kim, Hyung-Lae, Attia, John, Scott, Rodney J., Rao, D. C., Arnett, Donna K., Hunt, Steven C., Walker, Mark, Koistinen, Heikki A., Chandak, Giriraj R., Mercader, Josep M., Costanzo, Maria C., Jang, Dongkeun, Burtt, Noël P., Villalpando, Clicerio Gonzalez, Orozco, Lorena, Fornage, Myriam, Tai, EShyong, van Dam, Rob M., Lehtimäki, Terho, Chaturvedi, Nish, Yokota, Mitsuhiro, Liu, Jianjun, Reilly, Dermot F., McKnight, Amy Jayne, Kee, Frank, Jöckel, Karl-Heinz, McCarthy, Mark I., Palmer, Colin N. A., Vitart, Veronique, Hayward, Caroline, Simonsick, Eleanor, van Duijn, Cornelia M., Jin, Zi-Bing, Qu, Jia, Hishigaki, Haretsugu, Lin, Xu, März, Winfried, Gudnason, Vilmundur, Tardif, Jean-Claude, Lettre, Guillaume, Hart, Leen M.‘t, Elders, Petra J. M., Damrauer, Scott M., Kumari, Meena, Kivimaki, Mika, van der Harst, Pim, Spector, Tim D., Loos, Ruth J. F., Province, Michael A., Parra, Esteban J., Cruz, Miguel, Psaty, Bruce M., Brandslund, Ivan, Pramstaller, Peter P., Rotimi, Charles N., Christensen, Kaare, Ripatti, Samuli, Widén, Elisabeth, Hakonarson, Hakon, Grant, Struan F. A., Kiemeney, Lambertus A. L. M., de Graaf, Jacqueline, Loeffler, Markus, Kronenberg, Florian, Gu, Dongfeng, Erdmann, Jeanette, Schunkert, Heribert, Franks, Paul W., Linneberg, Allan, Jukema, J. Wouter, Khera, Amit V., Männikkö, Minna, Jarvelin, Marjo-Riitta, Kutalik, Zoltan, Francesco, Cucca, Mook-Kanamori, Dennis O., van Dijk, Ko Willems, Watkins, Hugh, Strachan, David P., Grarup, Niels, Sever, Peter, Poulter, Neil, Chuang, Lee-Ming, Rotter, Jerome I., Dantoft, Thomas M., Karpe, Fredrik, Neville, Matt J., Timpson, Nicholas J., Cheng, Ching-Yu, Wong, Tien-Yin, Khor, Chiea Chuen, Li, Hengtong, Sabanayagam, Charumathi, Peters, Annette, Gieger, Christian, Hattersley, Andrew T., Pedersen, Nancy L., Magnusson, Patrik K. E., Boomsma, Dorret I., Willemsen, Allegonda H. M., Cupples, LAdrienne, van Meurs, Joyce B. J., Ghanbari, Mohsen, Gordon-Larsen, Penny, Huang, Wei, Kim, Young Jin, Tabara, Yasuharu, Wareham, Nicholas J., Langenberg, Claudia, Zeggini, Eleftheria, Kuusisto, Johanna, Laakso, Markku, Ingelsson, Erik, Abecasis, Goncalo, Chambers, John C., Kooner, Jaspal S., de Vries, Paul S., Morrison, Alanna C., Hazelhurst, Scott, Ramsay, Michèle, North, Kari E., Daviglus, Martha, Kraft, Peter, Martin, Nicholas G., Whitfield, John B., Abbas, Shahid, Saleheen, Danish, Walters, Robin G., Holmes, Michael V., Black, Corri, Smith, Blair H., Baras, Aris, Justice, Anne E., Buring, Julie E., Ridker, Paul M., Chasman, Daniel I., Kooperberg, Charles, Tamiya, Gen, Yamamoto, Masayuki, van Heel, David A., Trembath, Richard C., Wei, Wei-Qi, Jarvik, Gail P., Namjou, Bahram, Hayes, M. Geoffrey, Ritchie, Marylyn D., Jousilahti, Pekka, Salomaa, Veikko, Hveem, Kristian, Åsvold, Bjørn Olav, Kubo, Michiaki, Kamatani, Yoichiro, Okada, Yukinori, Murakami, Yoshinori, Kim, Bong-Jo, Thorsteinsdottir, Unnur, Stefansson, Kari, Zhang, Jifeng, Chen, YEugene, Ho, Yuk-Lam, Lynch, Julie A., Rader, Daniel J., Tsao, Philip S., Chang, Kyong-Mi, Cho, Kelly, O’Donnell, Christopher J., Gaziano, John M., Wilson, Peter W. F., Frayling, Timothy M., Hirschhorn, Joel N., Kathiresan, Sekar, Mohlke, Karen L., Sun, Yan V., Morris, Andrew P., Boehnke, Michael, Brown, Christopher D., Natarajan, Pradeep, Deloukas, Panos, Willer, Cristen J., Assimes, Themistocles L., and Peloso, Gina M.
- Abstract
Additional file 26: Figure S10. Comparison of effect sizes for trans-ancestry index variants excluding cholesterol-lowering medication.
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- 2023
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35. Additional file 34 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
- Author
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Kanoni, Stavroula, Graham, Sarah E., Wang, Yuxuan, Surakka, Ida, Ramdas, Shweta, Zhu, Xiang, Clarke, Shoa L., Bhatti, Konain Fatima, Vedantam, Sailaja, Winkler, Thomas W., Locke, Adam E., Marouli, Eirini, Zajac, Greg J. M., Wu, Kuan-Han H., Ntalla, Ioanna, Hui, Qin, Klarin, Derek, Hilliard, Austin T., Wang, Zeyuan, Xue, Chao, Thorleifsson, Gudmar, Helgadottir, Anna, Gudbjartsson, Daniel F., Holm, Hilma, Olafsson, Isleifur, Hwang, Mi Yeong, Han, Sohee, Akiyama, Masato, Sakaue, Saori, Terao, Chikashi, Kanai, Masahiro, Zhou, Wei, Brumpton, Ben M., Rasheed, Humaira, Havulinna, Aki S., Veturi, Yogasudha, Pacheco, Jennifer Allen, Rosenthal, Elisabeth A., Lingren, Todd, Feng, QiPing, Kullo, Iftikhar J., Narita, Akira, Takayama, Jun, Martin, Hilary C., Hunt, Karen A., Trivedi, Bhavi, Haessler, Jeffrey, Giulianini, Franco, Bradford, Yuki, Miller, Jason E., Campbell, Archie, Lin, Kuang, Millwood, Iona Y., Rasheed, Asif, Hindy, George, Faul, Jessica D., Zhao, Wei, Weir, David R., Turman, Constance, Huang, Hongyan, Graff, Mariaelisa, Choudhury, Ananyo, Sengupta, Dhriti, Mahajan, Anubha, Brown, Michael R., Zhang, Weihua, Yu, Ketian, Schmidt, Ellen M., Pandit, Anita, Gustafsson, Stefan, Yin, Xianyong, Luan, Jian’an, Zhao, Jing-Hua, Matsuda, Fumihiko, Jang, Hye-Mi, Yoon, Kyungheon, Medina-Gomez, Carolina, Pitsillides, Achilleas, Hottenga, Jouke Jan, Wood, Andrew R., Ji, Yingji, Gao, Zishan, Haworth, Simon, Yousri, Noha A., Mitchell, Ruth E., Chai, Jin Fang, Aadahl, Mette, Bjerregaard, Anne A., Yao, Jie, Manichaikul, Ani, Hwu, Chii-Min, Hung, Yi-Jen, Warren, Helen R., Ramirez, Julia, Bork-Jensen, Jette, Kårhus, Line L., Goel, Anuj, Sabater-Lleal, Maria, Noordam, Raymond, Mauro, Pala, Matteo, Floris, McDaid, Aaron F., Marques-Vidal, Pedro, Wielscher, Matthias, Trompet, Stella, Sattar, Naveed, Møllehave, Line T., Munz, Matthias, Zeng, Lingyao, Huang, Jianfeng, Yang, Bin, Poveda, Alaitz, Kurbasic, Azra, Lamina, Claudia, Forer, Lukas, Scholz, Markus, Galesloot, Tessel E., Bradfield, Jonathan P., Ruotsalainen, Sanni E., Daw, EWarwick, Zmuda, Joseph M., Mitchell, Jonathan S., Fuchsberger, Christian, Christensen, Henry, Brody, Jennifer A., Vazquez-Moreno, Miguel, Feitosa, Mary F., Wojczynski, Mary K., Wang, Zhe, Preuss, Michael H., Mangino, Massimo, Christofidou, Paraskevi, Verweij, Niek, Benjamins, Jan W., Engmann, Jorgen, Tsao, Noah L., Verma, Anurag, Slieker, Roderick C., Lo, Ken Sin, Zilhao, Nuno R., Le, Phuong, Kleber, Marcus E., Delgado, Graciela E., Huo, Shaofeng, Ikeda, Daisuke D., Iha, Hiroyuki, Yang, Jian, Liu, Jun, Demirkan, Ayşe, Leonard, Hampton L., Marten, Jonathan, Frank, Mirjam, Schmidt, Börge, Smyth, Laura J., Cañadas-Garre, Marisa, Wang, Chaolong, Nakatochi, Masahiro, Wong, Andrew, Hutri-Kähönen, Nina, Sim, Xueling, Xia, Rui, Huerta-Chagoya, Alicia, Fernandez-Lopez, Juan Carlos, Lyssenko, Valeriya, Nongmaithem, Suraj S., Bayyana, Swati, Stringham, Heather M., Irvin, Marguerite R., Oldmeadow, Christopher, Kim, Han-Na, Ryu, Seungho, Timmers, Paul R. H. J., Arbeeva, Liubov, Dorajoo, Rajkumar, Lange, Leslie A., Prasad, Gauri, Lorés-Motta, Laura, Pauper, Marc, Long, Jirong, Li, Xiaohui, Theusch, Elizabeth, Takeuchi, Fumihiko, Spracklen, Cassandra N., Loukola, Anu, Bollepalli, Sailalitha, Warner, Sophie C., Wang, Ya Xing, Wei, Wen B., Nutile, Teresa, Ruggiero, Daniela, Sung, Yun Ju, Chen, Shufeng, Liu, Fangchao, Yang, Jingyun, Kentistou, Katherine A., Banas, Bernhard, Nardone, Giuseppe Giovanni, Meidtner, Karina, Bielak, Lawrence F., Smith, Jennifer A., Hebbar, Prashantha, Farmaki, Aliki-Eleni, Hofer, Edith, Lin, Maoxuan, Concas, Maria Pina, Vaccargiu, Simona, van der Most, Peter J., Pitkänen, Niina, Cade, Brian E., van der Laan, Sander W., Chitrala, Kumaraswamy Naidu, Weiss, Stefan, Bentley, Amy R., Doumatey, Ayo P., Adeyemo, Adebowale A., Lee, Jong Young, Petersen, Eva R. B., Nielsen, Aneta A., Choi, Hyeok Sun, Nethander, Maria, Freitag-Wolf, Sandra, Southam, Lorraine, Rayner, Nigel W., Wang, Carol A., Lin, Shih-Yi, Wang, Jun-Sing, Couture, Christian, Lyytikäinen, Leo-Pekka, Nikus, Kjell, Cuellar-Partida, Gabriel, Vestergaard, Henrik, Hidalgo, Bertha, Giannakopoulou, Olga, Cai, Qiuyin, Obura, Morgan O., van Setten, Jessica, Li, Xiaoyin, Liang, Jingjing, Tang, Hua, Terzikhan, Natalie, Shin, Jae Hun, Jackson, Rebecca D., Reiner, Alexander P., Martin, Lisa Warsinger, Chen, Zhengming, Li, Liming, Kawaguchi, Takahisa, Thiery, Joachim, Bis, Joshua C., Launer, Lenore J., Li, Huaixing, Nalls, Mike A., Raitakari, Olli T., Ichihara, Sahoko, Wild, Sarah H., Nelson, Christopher P., Campbell, Harry, Jäger, Susanne, Nabika, Toru, Al-Mulla, Fahd, Niinikoski, Harri, Braund, Peter S., Kolcic, Ivana, Kovacs, Peter, Giardoglou, Tota, Katsuya, Tomohiro, de Kleijn, Dominique, de Borst, Gert J., Kim, Eung Kweon, Adams, Hieab H. H., Ikram, M. Arfan, Zhu, Xiaofeng, Asselbergs, Folkert W., Kraaijeveld, Adriaan O., Beulens, Joline W. J., Shu, Xiao-Ou, Rallidis, Loukianos S., Pedersen, Oluf, Hansen, Torben, Mitchell, Paul, Hewitt, Alex W., Kähönen, Mika, Pérusse, Louis, Bouchard, Claude, Tönjes, Anke, Chen, Yii-Der Ida, Pennell, Craig E., Mori, Trevor A., Lieb, Wolfgang, Franke, Andre, Ohlsson, Claes, Mellström, Dan, Cho, Yoon Shin, Lee, Hyejin, Yuan, Jian-Min, Koh, Woon-Puay, Rhee, Sang Youl, Woo, Jeong-Taek, Heid, Iris M., Stark, Klaus J., Zimmermann, Martina E., Völzke, Henry, Homuth, Georg, Evans, Michele K., Zonderman, Alan B., Polasek, Ozren, Pasterkamp, Gerard, Hoefer, Imo E., Redline, Susan, Pahkala, Katja, Oldehinkel, Albertine J., Snieder, Harold, Biino, Ginevra, Schmidt, Reinhold, Schmidt, Helena, Bandinelli, Stefania, Dedoussis, George, Thanaraj, Thangavel Alphonse, Kardia, Sharon L. R., Peyser, Patricia A., Kato, Norihiro, Schulze, Matthias B., Girotto, Giorgia, Böger, Carsten A., Jung, Bettina, Joshi, Peter K., Bennett, David A., De Jager, Philip L., Lu, Xiangfeng, Mamakou, Vasiliki, Brown, Morris, Caulfield, Mark J., Munroe, Patricia B., Guo, Xiuqing, Ciullo, Marina, Jonas, Jost B., Samani, Nilesh J., Kaprio, Jaakko, Pajukanta, Päivi, Tusié-Luna, Teresa, Aguilar-Salinas, Carlos A., Adair, Linda S., Bechayda, Sonny Augustin, de Silva, H. Janaka, Wickremasinghe, Ananda R., Krauss, Ronald M., Wu, Jer-Yuarn, Zheng, Wei, Hollander, Anneke Iden, Bharadwaj, Dwaipayan, Correa, Adolfo, Wilson, James G., Lind, Lars, Heng, Chew-Kiat, Nelson, Amanda E., Golightly, Yvonne M., Wilson, James F., Penninx, Brenda, Kim, Hyung-Lae, Attia, John, Scott, Rodney J., Rao, D. C., Arnett, Donna K., Hunt, Steven C., Walker, Mark, Koistinen, Heikki A., Chandak, Giriraj R., Mercader, Josep M., Costanzo, Maria C., Jang, Dongkeun, Burtt, Noël P., Villalpando, Clicerio Gonzalez, Orozco, Lorena, Fornage, Myriam, Tai, EShyong, van Dam, Rob M., Lehtimäki, Terho, Chaturvedi, Nish, Yokota, Mitsuhiro, Liu, Jianjun, Reilly, Dermot F., McKnight, Amy Jayne, Kee, Frank, Jöckel, Karl-Heinz, McCarthy, Mark I., Palmer, Colin N. A., Vitart, Veronique, Hayward, Caroline, Simonsick, Eleanor, van Duijn, Cornelia M., Jin, Zi-Bing, Qu, Jia, Hishigaki, Haretsugu, Lin, Xu, März, Winfried, Gudnason, Vilmundur, Tardif, Jean-Claude, Lettre, Guillaume, Hart, Leen M.‘t, Elders, Petra J. M., Damrauer, Scott M., Kumari, Meena, Kivimaki, Mika, van der Harst, Pim, Spector, Tim D., Loos, Ruth J. F., Province, Michael A., Parra, Esteban J., Cruz, Miguel, Psaty, Bruce M., Brandslund, Ivan, Pramstaller, Peter P., Rotimi, Charles N., Christensen, Kaare, Ripatti, Samuli, Widén, Elisabeth, Hakonarson, Hakon, Grant, Struan F. A., Kiemeney, Lambertus A. L. M., de Graaf, Jacqueline, Loeffler, Markus, Kronenberg, Florian, Gu, Dongfeng, Erdmann, Jeanette, Schunkert, Heribert, Franks, Paul W., Linneberg, Allan, Jukema, J. Wouter, Khera, Amit V., Männikkö, Minna, Jarvelin, Marjo-Riitta, Kutalik, Zoltan, Francesco, Cucca, Mook-Kanamori, Dennis O., van Dijk, Ko Willems, Watkins, Hugh, Strachan, David P., Grarup, Niels, Sever, Peter, Poulter, Neil, Chuang, Lee-Ming, Rotter, Jerome I., Dantoft, Thomas M., Karpe, Fredrik, Neville, Matt J., Timpson, Nicholas J., Cheng, Ching-Yu, Wong, Tien-Yin, Khor, Chiea Chuen, Li, Hengtong, Sabanayagam, Charumathi, Peters, Annette, Gieger, Christian, Hattersley, Andrew T., Pedersen, Nancy L., Magnusson, Patrik K. E., Boomsma, Dorret I., Willemsen, Allegonda H. M., Cupples, LAdrienne, van Meurs, Joyce B. J., Ghanbari, Mohsen, Gordon-Larsen, Penny, Huang, Wei, Kim, Young Jin, Tabara, Yasuharu, Wareham, Nicholas J., Langenberg, Claudia, Zeggini, Eleftheria, Kuusisto, Johanna, Laakso, Markku, Ingelsson, Erik, Abecasis, Goncalo, Chambers, John C., Kooner, Jaspal S., de Vries, Paul S., Morrison, Alanna C., Hazelhurst, Scott, Ramsay, Michèle, North, Kari E., Daviglus, Martha, Kraft, Peter, Martin, Nicholas G., Whitfield, John B., Abbas, Shahid, Saleheen, Danish, Walters, Robin G., Holmes, Michael V., Black, Corri, Smith, Blair H., Baras, Aris, Justice, Anne E., Buring, Julie E., Ridker, Paul M., Chasman, Daniel I., Kooperberg, Charles, Tamiya, Gen, Yamamoto, Masayuki, van Heel, David A., Trembath, Richard C., Wei, Wei-Qi, Jarvik, Gail P., Namjou, Bahram, Hayes, M. Geoffrey, Ritchie, Marylyn D., Jousilahti, Pekka, Salomaa, Veikko, Hveem, Kristian, Åsvold, Bjørn Olav, Kubo, Michiaki, Kamatani, Yoichiro, Okada, Yukinori, Murakami, Yoshinori, Kim, Bong-Jo, Thorsteinsdottir, Unnur, Stefansson, Kari, Zhang, Jifeng, Chen, YEugene, Ho, Yuk-Lam, Lynch, Julie A., Rader, Daniel J., Tsao, Philip S., Chang, Kyong-Mi, Cho, Kelly, O’Donnell, Christopher J., Gaziano, John M., Wilson, Peter W. F., Frayling, Timothy M., Hirschhorn, Joel N., Kathiresan, Sekar, Mohlke, Karen L., Sun, Yan V., Morris, Andrew P., Boehnke, Michael, Brown, Christopher D., Natarajan, Pradeep, Deloukas, Panos, Willer, Cristen J., Assimes, Themistocles L., and Peloso, Gina M.
- Abstract
Additional file 34. Review history.
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- 2023
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- View/download PDF
36. Additional file 16 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
- Author
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Kanoni, Stavroula, Graham, Sarah E., Wang, Yuxuan, Surakka, Ida, Ramdas, Shweta, Zhu, Xiang, Clarke, Shoa L., Bhatti, Konain Fatima, Vedantam, Sailaja, Winkler, Thomas W., Locke, Adam E., Marouli, Eirini, Zajac, Greg J. M., Wu, Kuan-Han H., Ntalla, Ioanna, Hui, Qin, Klarin, Derek, Hilliard, Austin T., Wang, Zeyuan, Xue, Chao, Thorleifsson, Gudmar, Helgadottir, Anna, Gudbjartsson, Daniel F., Holm, Hilma, Olafsson, Isleifur, Hwang, Mi Yeong, Han, Sohee, Akiyama, Masato, Sakaue, Saori, Terao, Chikashi, Kanai, Masahiro, Zhou, Wei, Brumpton, Ben M., Rasheed, Humaira, Havulinna, Aki S., Veturi, Yogasudha, Pacheco, Jennifer Allen, Rosenthal, Elisabeth A., Lingren, Todd, Feng, QiPing, Kullo, Iftikhar J., Narita, Akira, Takayama, Jun, Martin, Hilary C., Hunt, Karen A., Trivedi, Bhavi, Haessler, Jeffrey, Giulianini, Franco, Bradford, Yuki, Miller, Jason E., Campbell, Archie, Lin, Kuang, Millwood, Iona Y., Rasheed, Asif, Hindy, George, Faul, Jessica D., Zhao, Wei, Weir, David R., Turman, Constance, Huang, Hongyan, Graff, Mariaelisa, Choudhury, Ananyo, Sengupta, Dhriti, Mahajan, Anubha, Brown, Michael R., Zhang, Weihua, Yu, Ketian, Schmidt, Ellen M., Pandit, Anita, Gustafsson, Stefan, Yin, Xianyong, Luan, Jian’an, Zhao, Jing-Hua, Matsuda, Fumihiko, Jang, Hye-Mi, Yoon, Kyungheon, Medina-Gomez, Carolina, Pitsillides, Achilleas, Hottenga, Jouke Jan, Wood, Andrew R., Ji, Yingji, Gao, Zishan, Haworth, Simon, Yousri, Noha A., Mitchell, Ruth E., Chai, Jin Fang, Aadahl, Mette, Bjerregaard, Anne A., Yao, Jie, Manichaikul, Ani, Hwu, Chii-Min, Hung, Yi-Jen, Warren, Helen R., Ramirez, Julia, Bork-Jensen, Jette, Kårhus, Line L., Goel, Anuj, Sabater-Lleal, Maria, Noordam, Raymond, Mauro, Pala, Matteo, Floris, McDaid, Aaron F., Marques-Vidal, Pedro, Wielscher, Matthias, Trompet, Stella, Sattar, Naveed, Møllehave, Line T., Munz, Matthias, Zeng, Lingyao, Huang, Jianfeng, Yang, Bin, Poveda, Alaitz, Kurbasic, Azra, Lamina, Claudia, Forer, Lukas, Scholz, Markus, Galesloot, Tessel E., Bradfield, Jonathan P., Ruotsalainen, Sanni E., Daw, EWarwick, Zmuda, Joseph M., Mitchell, Jonathan S., Fuchsberger, Christian, Christensen, Henry, Brody, Jennifer A., Vazquez-Moreno, Miguel, Feitosa, Mary F., Wojczynski, Mary K., Wang, Zhe, Preuss, Michael H., Mangino, Massimo, Christofidou, Paraskevi, Verweij, Niek, Benjamins, Jan W., Engmann, Jorgen, Tsao, Noah L., Verma, Anurag, Slieker, Roderick C., Lo, Ken Sin, Zilhao, Nuno R., Le, Phuong, Kleber, Marcus E., Delgado, Graciela E., Huo, Shaofeng, Ikeda, Daisuke D., Iha, Hiroyuki, Yang, Jian, Liu, Jun, Demirkan, Ayşe, Leonard, Hampton L., Marten, Jonathan, Frank, Mirjam, Schmidt, Börge, Smyth, Laura J., Cañadas-Garre, Marisa, Wang, Chaolong, Nakatochi, Masahiro, Wong, Andrew, Hutri-Kähönen, Nina, Sim, Xueling, Xia, Rui, Huerta-Chagoya, Alicia, Fernandez-Lopez, Juan Carlos, Lyssenko, Valeriya, Nongmaithem, Suraj S., Bayyana, Swati, Stringham, Heather M., Irvin, Marguerite R., Oldmeadow, Christopher, Kim, Han-Na, Ryu, Seungho, Timmers, Paul R. H. J., Arbeeva, Liubov, Dorajoo, Rajkumar, Lange, Leslie A., Prasad, Gauri, Lorés-Motta, Laura, Pauper, Marc, Long, Jirong, Li, Xiaohui, Theusch, Elizabeth, Takeuchi, Fumihiko, Spracklen, Cassandra N., Loukola, Anu, Bollepalli, Sailalitha, Warner, Sophie C., Wang, Ya Xing, Wei, Wen B., Nutile, Teresa, Ruggiero, Daniela, Sung, Yun Ju, Chen, Shufeng, Liu, Fangchao, Yang, Jingyun, Kentistou, Katherine A., Banas, Bernhard, Nardone, Giuseppe Giovanni, Meidtner, Karina, Bielak, Lawrence F., Smith, Jennifer A., Hebbar, Prashantha, Farmaki, Aliki-Eleni, Hofer, Edith, Lin, Maoxuan, Concas, Maria Pina, Vaccargiu, Simona, van der Most, Peter J., Pitkänen, Niina, Cade, Brian E., van der Laan, Sander W., Chitrala, Kumaraswamy Naidu, Weiss, Stefan, Bentley, Amy R., Doumatey, Ayo P., Adeyemo, Adebowale A., Lee, Jong Young, Petersen, Eva R. B., Nielsen, Aneta A., Choi, Hyeok Sun, Nethander, Maria, Freitag-Wolf, Sandra, Southam, Lorraine, Rayner, Nigel W., Wang, Carol A., Lin, Shih-Yi, Wang, Jun-Sing, Couture, Christian, Lyytikäinen, Leo-Pekka, Nikus, Kjell, Cuellar-Partida, Gabriel, Vestergaard, Henrik, Hidalgo, Bertha, Giannakopoulou, Olga, Cai, Qiuyin, Obura, Morgan O., van Setten, Jessica, Li, Xiaoyin, Liang, Jingjing, Tang, Hua, Terzikhan, Natalie, Shin, Jae Hun, Jackson, Rebecca D., Reiner, Alexander P., Martin, Lisa Warsinger, Chen, Zhengming, Li, Liming, Kawaguchi, Takahisa, Thiery, Joachim, Bis, Joshua C., Launer, Lenore J., Li, Huaixing, Nalls, Mike A., Raitakari, Olli T., Ichihara, Sahoko, Wild, Sarah H., Nelson, Christopher P., Campbell, Harry, Jäger, Susanne, Nabika, Toru, Al-Mulla, Fahd, Niinikoski, Harri, Braund, Peter S., Kolcic, Ivana, Kovacs, Peter, Giardoglou, Tota, Katsuya, Tomohiro, de Kleijn, Dominique, de Borst, Gert J., Kim, Eung Kweon, Adams, Hieab H. H., Ikram, M. Arfan, Zhu, Xiaofeng, Asselbergs, Folkert W., Kraaijeveld, Adriaan O., Beulens, Joline W. J., Shu, Xiao-Ou, Rallidis, Loukianos S., Pedersen, Oluf, Hansen, Torben, Mitchell, Paul, Hewitt, Alex W., Kähönen, Mika, Pérusse, Louis, Bouchard, Claude, Tönjes, Anke, Chen, Yii-Der Ida, Pennell, Craig E., Mori, Trevor A., Lieb, Wolfgang, Franke, Andre, Ohlsson, Claes, Mellström, Dan, Cho, Yoon Shin, Lee, Hyejin, Yuan, Jian-Min, Koh, Woon-Puay, Rhee, Sang Youl, Woo, Jeong-Taek, Heid, Iris M., Stark, Klaus J., Zimmermann, Martina E., Völzke, Henry, Homuth, Georg, Evans, Michele K., Zonderman, Alan B., Polasek, Ozren, Pasterkamp, Gerard, Hoefer, Imo E., Redline, Susan, Pahkala, Katja, Oldehinkel, Albertine J., Snieder, Harold, Biino, Ginevra, Schmidt, Reinhold, Schmidt, Helena, Bandinelli, Stefania, Dedoussis, George, Thanaraj, Thangavel Alphonse, Kardia, Sharon L. R., Peyser, Patricia A., Kato, Norihiro, Schulze, Matthias B., Girotto, Giorgia, Böger, Carsten A., Jung, Bettina, Joshi, Peter K., Bennett, David A., De Jager, Philip L., Lu, Xiangfeng, Mamakou, Vasiliki, Brown, Morris, Caulfield, Mark J., Munroe, Patricia B., Guo, Xiuqing, Ciullo, Marina, Jonas, Jost B., Samani, Nilesh J., Kaprio, Jaakko, Pajukanta, Päivi, Tusié-Luna, Teresa, Aguilar-Salinas, Carlos A., Adair, Linda S., Bechayda, Sonny Augustin, de Silva, H. Janaka, Wickremasinghe, Ananda R., Krauss, Ronald M., Wu, Jer-Yuarn, Zheng, Wei, Hollander, Anneke Iden, Bharadwaj, Dwaipayan, Correa, Adolfo, Wilson, James G., Lind, Lars, Heng, Chew-Kiat, Nelson, Amanda E., Golightly, Yvonne M., Wilson, James F., Penninx, Brenda, Kim, Hyung-Lae, Attia, John, Scott, Rodney J., Rao, D. C., Arnett, Donna K., Hunt, Steven C., Walker, Mark, Koistinen, Heikki A., Chandak, Giriraj R., Mercader, Josep M., Costanzo, Maria C., Jang, Dongkeun, Burtt, Noël P., Villalpando, Clicerio Gonzalez, Orozco, Lorena, Fornage, Myriam, Tai, EShyong, van Dam, Rob M., Lehtimäki, Terho, Chaturvedi, Nish, Yokota, Mitsuhiro, Liu, Jianjun, Reilly, Dermot F., McKnight, Amy Jayne, Kee, Frank, Jöckel, Karl-Heinz, McCarthy, Mark I., Palmer, Colin N. A., Vitart, Veronique, Hayward, Caroline, Simonsick, Eleanor, van Duijn, Cornelia M., Jin, Zi-Bing, Qu, Jia, Hishigaki, Haretsugu, Lin, Xu, März, Winfried, Gudnason, Vilmundur, Tardif, Jean-Claude, Lettre, Guillaume, Hart, Leen M.‘t, Elders, Petra J. M., Damrauer, Scott M., Kumari, Meena, Kivimaki, Mika, van der Harst, Pim, Spector, Tim D., Loos, Ruth J. F., Province, Michael A., Parra, Esteban J., Cruz, Miguel, Psaty, Bruce M., Brandslund, Ivan, Pramstaller, Peter P., Rotimi, Charles N., Christensen, Kaare, Ripatti, Samuli, Widén, Elisabeth, Hakonarson, Hakon, Grant, Struan F. A., Kiemeney, Lambertus A. L. M., de Graaf, Jacqueline, Loeffler, Markus, Kronenberg, Florian, Gu, Dongfeng, Erdmann, Jeanette, Schunkert, Heribert, Franks, Paul W., Linneberg, Allan, Jukema, J. Wouter, Khera, Amit V., Männikkö, Minna, Jarvelin, Marjo-Riitta, Kutalik, Zoltan, Francesco, Cucca, Mook-Kanamori, Dennis O., van Dijk, Ko Willems, Watkins, Hugh, Strachan, David P., Grarup, Niels, Sever, Peter, Poulter, Neil, Chuang, Lee-Ming, Rotter, Jerome I., Dantoft, Thomas M., Karpe, Fredrik, Neville, Matt J., Timpson, Nicholas J., Cheng, Ching-Yu, Wong, Tien-Yin, Khor, Chiea Chuen, Li, Hengtong, Sabanayagam, Charumathi, Peters, Annette, Gieger, Christian, Hattersley, Andrew T., Pedersen, Nancy L., Magnusson, Patrik K. E., Boomsma, Dorret I., Willemsen, Allegonda H. M., Cupples, LAdrienne, van Meurs, Joyce B. J., Ghanbari, Mohsen, Gordon-Larsen, Penny, Huang, Wei, Kim, Young Jin, Tabara, Yasuharu, Wareham, Nicholas J., Langenberg, Claudia, Zeggini, Eleftheria, Kuusisto, Johanna, Laakso, Markku, Ingelsson, Erik, Abecasis, Goncalo, Chambers, John C., Kooner, Jaspal S., de Vries, Paul S., Morrison, Alanna C., Hazelhurst, Scott, Ramsay, Michèle, North, Kari E., Daviglus, Martha, Kraft, Peter, Martin, Nicholas G., Whitfield, John B., Abbas, Shahid, Saleheen, Danish, Walters, Robin G., Holmes, Michael V., Black, Corri, Smith, Blair H., Baras, Aris, Justice, Anne E., Buring, Julie E., Ridker, Paul M., Chasman, Daniel I., Kooperberg, Charles, Tamiya, Gen, Yamamoto, Masayuki, van Heel, David A., Trembath, Richard C., Wei, Wei-Qi, Jarvik, Gail P., Namjou, Bahram, Hayes, M. Geoffrey, Ritchie, Marylyn D., Jousilahti, Pekka, Salomaa, Veikko, Hveem, Kristian, Åsvold, Bjørn Olav, Kubo, Michiaki, Kamatani, Yoichiro, Okada, Yukinori, Murakami, Yoshinori, Kim, Bong-Jo, Thorsteinsdottir, Unnur, Stefansson, Kari, Zhang, Jifeng, Chen, YEugene, Ho, Yuk-Lam, Lynch, Julie A., Rader, Daniel J., Tsao, Philip S., Chang, Kyong-Mi, Cho, Kelly, O’Donnell, Christopher J., Gaziano, John M., Wilson, Peter W. F., Frayling, Timothy M., Hirschhorn, Joel N., Kathiresan, Sekar, Mohlke, Karen L., Sun, Yan V., Morris, Andrew P., Boehnke, Michael, Brown, Christopher D., Natarajan, Pradeep, Deloukas, Panos, Willer, Cristen J., Assimes, Themistocles L., and Peloso, Gina M.
- Abstract
Additional file 16: Figure S8. PheWAS meta-analysis results for the trans-ethnic nonHDL-C PGS in UK Biobank and MVP.
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- 2023
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37. Author Correction : The power of genetic diversity in genome-wide association studies of lipids
- Author
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Graham, Sarah E., Clarke, Shoa L., Wu, Kuan-Han H., Kanoni, Stavroula, Zajac, Greg J. M., Ramdas, Shweta, Surakka, Ida, Ntalla, Ioanna, Vedantam, Sailaja, Winkler, Thomas W., Locke, Adam E., Marouli, Eirini, Hwang, Mi Yeong, Han, Sohee, Narita, Akira, Choudhury, Ananyo, Bentley, Amy R., Ekoru, Kenneth, Verma, Anurag, Trivedi, Bhavi, Martin, Hilary C., Hunt, Karen A., Hui, Qin, Klarin, Derek, Zhu, Xiang, Thorleifsson, Gudmar, Helgadottir, Anna, Gudbjartsson, Daniel F., Holm, Hilma, Olafsson, Isleifur, Akiyama, Masato, Sakaue, Saori, Terao, Chikashi, Kanai, Masahiro, Zhou, Wei, Brumpton, Ben M., Rasheed, Humaira, Ruotsalainen, Sanni E., Havulinna, Aki S., Veturi, Yogasudha, Feng, QiPing, Rosenthal, Elisabeth A., Lingren, Todd, Pacheco, Jennifer Allen, Pendergrass, Sarah A., Haessler, Jeffrey, Giulianini, Franco, Bradford, Yuki, Miller, Jason E., Campbell, Archie, Lin, Kuang, Millwood, Iona Y., Hindy, George, Rasheed, Asif, Faul, Jessica D., Zhao, Wei, Weir, David R., Turman, Constance, Huang, Hongyan, Graff, Mariaelisa, Mahajan, Anubha, Brown, Michael R., Zhang, Weihua, Yu, Ketian, Schmidt, Ellen M., Pandit, Anita, Gustafsson, Stefan, Yin, Xianyong, Luan, Jian’an, Zhao, Jing-Hua, Matsuda, Fumihiko, Jang, Hye-Mi, Yoon, Kyungheon, Medina-Gomez, Carolina, Pitsillides, Achilleas, Hottenga, Jouke Jan, Willemsen, Gonneke, Wood, Andrew R., Ji, Yingji, Gao, Zishan, Haworth, Simon, Mitchell, Ruth E., Chai, Jin Fang, Aadahl, Mette, Yao, Jie, Manichaikul, Ani, Warren, Helen R., Ramirez, Julia, Bork-Jensen, Jette, Kårhus, Line L., Goel, Anuj, Sabater-Lleal, Maria, Noordam, Raymond, Sidore, Carlo, Fiorillo, Edoardo, McDaid, Aaron F., Marques-Vidal, Pedro, Wielscher, Matthias, Trompet, Stella, Sattar, Naveed, Møllehave, Line T., Thuesen, Betina H., Munz, Matthias, Zeng, Lingyao, Huang, Jianfeng, Yang, Bin, Poveda, Alaitz, Kurbasic, Azra, Lamina, Claudia, Forer, Lukas, Scholz, Markus, Galesloot, Tessel E., Bradfield, Jonathan P., Daw, E. Warwick, Zmuda, Joseph M., Mitchell, Jonathan S., Fuchsberger, Christian, Christensen, Henry, Brody, Jennifer A., Feitosa, Mary F., Wojczynski, Mary K., Preuss, Michael, Mangino, Massimo, Christofidou, Paraskevi, Verweij, Niek, Benjamins, Jan W., Engmann, Jorgen, Kember, Rachel L., Slieker, Roderick C., Lo, Ken Sin, Zilhao, Nuno R., Le, Phuong, Kleber, Marcus E., Delgado, Graciela E., Huo, Shaofeng, Ikeda, Daisuke D., Iha, Hiroyuki, Yang, Jian, Liu, Jun, Leonard, Hampton L., Marten, Jonathan, Schmidt, Börge, Arendt, Marina, Smyth, Laura J., Cañadas-Garre, Marisa, Wang, Chaolong, Nakatochi, Masahiro, Wong, Andrew, Hutri-Kähönen, Nina, Sim, Xueling, Xia, Rui, Huerta-Chagoya, Alicia, Fernandez-Lopez, Juan Carlos, Lyssenko, Valeriya, Ahmed, Meraj, Jackson, Anne U., Yousri, Noha A., Irvin, Marguerite R., Oldmeadow, Christopher, Kim, Han-Na, Ryu, Seungho, Timmers, Paul R. H. J., Arbeeva, Liubov, Dorajoo, Rajkumar, Lange, Leslie A., Chai, Xiaoran, Prasad, Gauri, Lorés-Motta, Laura, Pauper, Marc, Long, Jirong, Li, Xiaohui, Theusch, Elizabeth, Takeuchi, Fumihiko, Spracklen, Cassandra N., Loukola, Anu, Bollepalli, Sailalitha, Warner, Sophie C., Wang, Ya Xing, Wei, Wen B., Nutile, Teresa, Ruggiero, Daniela, Sung, Yun Ju, Hung, Yi-Jen, Chen, Shufeng, Liu, Fangchao, Yang, Jingyun, Kentistou, Katherine A., Gorski, Mathias, Brumat, Marco, Meidtner, Karina, Bielak, Lawrence F., Smith, Jennifer A., Hebbar, Prashantha, Farmaki, Aliki-Eleni, Hofer, Edith, Lin, Maoxuan, Xue, Chao, Zhang, Jifeng, Concas, Maria Pina, Vaccargiu, Simona, van der Most, Peter J., Pitkänen, Niina, Cade, Brian E., Lee, Jiwon, van der Laan, Sander W., Chitrala, Kumaraswamy Naidu, Weiss, Stefan, Zimmermann, Martina E., Lee, Jong Young, Choi, Hyeok Sun, Nethander, Maria, Freitag-Wolf, Sandra, Southam, Lorraine, Rayner, Nigel W., Wang, Carol A., Lin, Shih-Yi, Wang, Jun-Sing, Couture, Christian, Lyytikäinen, Leo-Pekka, Nikus, Kjell, Cuellar-Partida, Gabriel, Vestergaard, Henrik, Hildalgo, Bertha, Giannakopoulou, Olga, Cai, Qiuyin, Obura, Morgan O., van Setten, Jessica, Li, Xiaoyin, Schwander, Karen, Terzikhan, Natalie, Shin, Jae Hun, Jackson, Rebecca D., Reiner, Alexander P., Martin, Lisa Warsinger, Chen, Zhengming, Li, Liming, Highland, Heather M., Young, Kristin L., Kawaguchi, Takahisa, Thiery, Joachim, Bis, Joshua C., Nadkarni, Girish N., Launer, Lenore J., Li, Huaixing, Nalls, Mike A., Raitakari, Olli T., Ichihara, Sahoko, Wild, Sarah H., Nelson, Christopher P., Campbell, Harry, Jäger, Susanne, Nabika, Toru, Al-Mulla, Fahd, Niinikoski, Harri, Braund, Peter S., Kolcic, Ivana, Kovacs, Peter, Giardoglou, Tota, Katsuya, Tomohiro, Bhatti, Konain Fatima, de Kleijn, Dominique, de Borst, Gert J., Kim, Eung Kweon, Adams, Hieab H. H., Ikram, M. Arfan, Zhu, Xiaofeng, Asselbergs, Folkert W., Kraaijeveld, Adriaan O., Beulens, Joline W. J., Shu, Xiao-Ou, Rallidis, Loukianos S., Pedersen, Oluf, Hansen, Torben, Mitchell, Paul, Hewitt, Alex W., Kähönen, Mika, Pérusse, Louis, Bouchard, Claude, Tönjes, Anke, Chen, Yii-Der Ida, Pennell, Craig E., Mori, Trevor A., Lieb, Wolfgang, Franke, Andre, Ohlsson, Claes, Mellström, Dan, Cho, Yoon Shin, Lee, Hyejin, Yuan, Jian-Min, Koh, Woon-Puay, Rhee, Sang Youl, Woo, Jeong-Taek, Heid, Iris M., Stark, Klaus J., Völzke, Henry, Homuth, Georg, Evans, Michele K., Zonderman, Alan B., Polasek, Ozren, Pasterkamp, Gerard, Hoefer, Imo E., Redline, Susan, Pahkala, Katja, Oldehinkel, Albertine J., Snieder, Harold, Biino, Ginevra, Schmidt, Reinhold, Schmidt, Helena, Chen, Y. Eugene, Bandinelli, Stefania, Dedoussis, George, Thanaraj, Thangavel Alphonse, Kardia, Sharon L. R., Kato, Norihiro, Schulze, Matthias B., Girotto, Giorgia, Jung, Bettina, Böger, Carsten A., Joshi, Peter K., Bennett, David A., De Jager, Philip L., Lu, Xiangfeng, Mamakou, Vasiliki, Brown, Morris, Caulfield, Mark J., Munroe, Patricia B., Guo, Xiuqing, Ciullo, Marina, Jonas, Jost B., Samani, Nilesh J., Kaprio, Jaakko, Pajukanta, Päivi, Adair, Linda S., Bechayda, Sonny Augustin, de Silva, H. Janaka, Wickremasinghe, Ananda R., Krauss, Ronald M., Wu, Jer-Yuarn, Zheng, Wei, den Hollander, Anneke I., Bharadwaj, Dwaipayan, Correa, Adolfo, Wilson, James G., Lind, Lars, Heng, Chew-Kiat, Nelson, Amanda E., Golightly, Yvonne M., Wilson, James F., Penninx, Brenda, Kim, Hyung-Lae, Attia, John, Scott, Rodney J., Rao, D.C., Arnett, Donna K., Hunt, Steven C., Walker, Mark, Koistinen, Heikki A., Chandak, Giriraj R., Yajnik, Chittaranjan S., Mercader, Josep M., Tusié-Luna, Teresa, Aguilar-Salinas, Carlos A., Villalpando, Clicerio Gonzalez, Orozco, Lorena, Fornage, Myriam, Tai, E. Shyong, van Dam, Rob M., Lehtimäki, Terho, Chaturvedi, Nish, Yokota, Mitsuhiro, Liu, Jianjun, Reilly, Dermot F., McKnight, Amy Jayne, Kee, Frank, Jöckel, Karl-Heinz, McCarthy, Mark I., Palmer, Colin N. A., Vitart, Veronique, Hayward, Caroline, Simonsick, Eleanor, van Duijn, Cornelia M., Lu, Fan, Qu, Jia, Hishigaki, Haretsugu, Lin, Xu, März, Winfried, Parra, Esteban J., Cruz, Miguel, Gudnason, Vilmundur, Tardif, Jean-Claude, Lettre, Guillaume, ’t Hart, Leen M., Elders, Petra J. M., Damrauer, Scott M., Kumari, Meena, Kivimaki, Mika, van der Harst, Pim, Spector, Tim D., Loos, Ruth J. F., Province, Michael A., Psaty, Bruce M., Brandslund, Ivan, Pramstaller, Peter P., Christensen, Kaare, Ripatti, Samuli, Widén, Elisabeth, Hakonarson, Hakon, Grant, Struan F. A., Kiemeney, Lambertus A. L. M., de Graaf, Jacqueline, Loeffler, Markus, Kronenberg, Florian, Gu, Dongfeng, Erdmann, Jeanette, Schunkert, Heribert, Franks, Paul W., Linneberg, Allan, Jukema, J. Wouter, Khera, Amit V., Männikkö, Minna, Jarvelin, Marjo-Riitta, Kutalik, Zoltan, Cucca, Francesco, Mook-Kanamori, Dennis O., van Dijk, Ko Willems, Watkins, Hugh, Strachan, David P., Grarup, Niels, Sever, Peter, Poulter, Neil, Rotter, Jerome I., Dantoft, Thomas M., Karpe, Fredrik, Neville, Matt J., Timpson, Nicholas J., Cheng, Ching-Yu, Wong, Tien-Yin, Khor, Chiea Chuen, Sabanayagam, Charumathi, Peters, Annette, Gieger, Christian, Hattersley, Andrew T., Pedersen, Nancy L., Magnusson, Patrik K. E., Boomsma, Dorret I., de Geus, Eco J. C., Cupples, L. Adrienne, van Meurs, Joyce B. J., Ghanbari, Mohsen, Gordon-Larsen, Penny, Huang, Wei, Kim, Young Jin, Tabara, Yasuharu, Wareham, Nicholas J., Langenberg, Claudia, Zeggini, Eleftheria, Kuusisto, Johanna, Laakso, Markku, Ingelsson, Erik, Abecasis, Goncalo, Chambers, John C., Kooner, Jaspal S., de Vries, Paul S., Morrison, Alanna C., North, Kari E., Daviglus, Martha, Kraft, Peter, Martin, Nicholas G., Whitfield, John B., Abbas, Shahid, Saleheen, Danish, Walters, Robin G., Holmes, Michael V., Black, Corri, Smith, Blair H., Justice, Anne E., Baras, Aris, Buring, Julie E., Ridker, Paul M., Chasman, Daniel I., Kooperberg, Charles, Wei, Wei-Qi, Jarvik, Gail P., Namjou, Bahram, Hayes, M. Geoffrey, Ritchie, Marylyn D., Jousilahti, Pekka, Salomaa, Veikko, Hveem, Kristian, Åsvold, Bjørn Olav, Kubo, Michiaki, Kamatani, Yoichiro, Okada, Yukinori, Murakami, Yoshinori, Thorsteinsdottir, Unnur, Stefansson, Kari, Ho, Yuk-Lam, Lynch, Julie A., Rader, Daniel J., Tsao, Philip S., Chang, Kyong-Mi, Cho, Kelly, O’Donnell, Christopher J., Gaziano, John M., Wilson, Peter, Rotimi, Charles N., Hazelhurst, Scott, Ramsay, Michèle, Trembath, Richard C., van Heel, David A., Tamiya, Gen, Yamamoto, Masayuki, Kim, Bong-Jo, Mohlke, Karen L., Frayling, Timothy M., Hirschhorn, Joel N., Kathiresan, Sekar, Boehnke, Michael, Natarajan, Pradeep, Peloso, Gina M., Brown, Christopher D., Morris, Andrew P., Assimes, Themistocles L., Deloukas, Panos, Sun, Yan V., and Willer, Cristen J.
- Subjects
Medizin - Abstract
Correction to: Nature Published online 9 December 2021 In the version of this article initially published, Noha A. Yousri (Department of Genetic Medicine, Weill Cornell Medicine-Qatar, Doha, Qatar and Department of Computer and Systems Engineering, Alexandria University, Egypt) and Steven C. Hunt (Department of Internal Medicine, University of Utah, Salt Lake City, UT, USA and Department of Genetic Medicine, Weill Cornell Medicine-Qatar, Doha, Qatar) were not included in the author list. In addition, Hieab H. H. Adams (Department of Radiology and Nuclear Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands and Department of Clinical Genetics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands) was shown with an incorrect second affiliation in the HTML and PDF versions of the article. Finally, in the HTML version, Cristen J. Willer was mistakenly listed with an extra affiliation (Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia). The authors and affiliations have been corrected in the HTML and PDF versions of the article.
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38. Additional file 6 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
- Author
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Kanoni, Stavroula, Graham, Sarah E., Wang, Yuxuan, Surakka, Ida, Ramdas, Shweta, Zhu, Xiang, Clarke, Shoa L., Bhatti, Konain Fatima, Vedantam, Sailaja, Winkler, Thomas W., Locke, Adam E., Marouli, Eirini, Zajac, Greg J. M., Wu, Kuan-Han H., Ntalla, Ioanna, Hui, Qin, Klarin, Derek, Hilliard, Austin T., Wang, Zeyuan, Xue, Chao, Thorleifsson, Gudmar, Helgadottir, Anna, Gudbjartsson, Daniel F., Holm, Hilma, Olafsson, Isleifur, Hwang, Mi Yeong, Han, Sohee, Akiyama, Masato, Sakaue, Saori, Terao, Chikashi, Kanai, Masahiro, Zhou, Wei, Brumpton, Ben M., Rasheed, Humaira, Havulinna, Aki S., Veturi, Yogasudha, Pacheco, Jennifer Allen, Rosenthal, Elisabeth A., Lingren, Todd, Feng, QiPing, Kullo, Iftikhar J., Narita, Akira, Takayama, Jun, Martin, Hilary C., Hunt, Karen A., Trivedi, Bhavi, Haessler, Jeffrey, Giulianini, Franco, Bradford, Yuki, Miller, Jason E., Campbell, Archie, Lin, Kuang, Millwood, Iona Y., Rasheed, Asif, Hindy, George, Faul, Jessica D., Zhao, Wei, Weir, David R., Turman, Constance, Huang, Hongyan, Graff, Mariaelisa, Choudhury, Ananyo, Sengupta, Dhriti, Mahajan, Anubha, Brown, Michael R., Zhang, Weihua, Yu, Ketian, Schmidt, Ellen M., Pandit, Anita, Gustafsson, Stefan, Yin, Xianyong, Luan, Jian’an, Zhao, Jing-Hua, Matsuda, Fumihiko, Jang, Hye-Mi, Yoon, Kyungheon, Medina-Gomez, Carolina, Pitsillides, Achilleas, Hottenga, Jouke Jan, Wood, Andrew R., Ji, Yingji, Gao, Zishan, Haworth, Simon, Yousri, Noha A., Mitchell, Ruth E., Chai, Jin Fang, Aadahl, Mette, Bjerregaard, Anne A., Yao, Jie, Manichaikul, Ani, Hwu, Chii-Min, Hung, Yi-Jen, Warren, Helen R., Ramirez, Julia, Bork-Jensen, Jette, Kårhus, Line L., Goel, Anuj, Sabater-Lleal, Maria, Noordam, Raymond, Mauro, Pala, Matteo, Floris, McDaid, Aaron F., Marques-Vidal, Pedro, Wielscher, Matthias, Trompet, Stella, Sattar, Naveed, Møllehave, Line T., Munz, Matthias, Zeng, Lingyao, Huang, Jianfeng, Yang, Bin, Poveda, Alaitz, Kurbasic, Azra, Lamina, Claudia, Forer, Lukas, Scholz, Markus, Galesloot, Tessel E., Bradfield, Jonathan P., Ruotsalainen, Sanni E., Daw, EWarwick, Zmuda, Joseph M., Mitchell, Jonathan S., Fuchsberger, Christian, Christensen, Henry, Brody, Jennifer A., Vazquez-Moreno, Miguel, Feitosa, Mary F., Wojczynski, Mary K., Wang, Zhe, Preuss, Michael H., Mangino, Massimo, Christofidou, Paraskevi, Verweij, Niek, Benjamins, Jan W., Engmann, Jorgen, Tsao, Noah L., Verma, Anurag, Slieker, Roderick C., Lo, Ken Sin, Zilhao, Nuno R., Le, Phuong, Kleber, Marcus E., Delgado, Graciela E., Huo, Shaofeng, Ikeda, Daisuke D., Iha, Hiroyuki, Yang, Jian, Liu, Jun, Demirkan, Ayşe, Leonard, Hampton L., Marten, Jonathan, Frank, Mirjam, Schmidt, Börge, Smyth, Laura J., Cañadas-Garre, Marisa, Wang, Chaolong, Nakatochi, Masahiro, Wong, Andrew, Hutri-Kähönen, Nina, Sim, Xueling, Xia, Rui, Huerta-Chagoya, Alicia, Fernandez-Lopez, Juan Carlos, Lyssenko, Valeriya, Nongmaithem, Suraj S., Bayyana, Swati, Stringham, Heather M., Irvin, Marguerite R., Oldmeadow, Christopher, Kim, Han-Na, Ryu, Seungho, Timmers, Paul R. H. J., Arbeeva, Liubov, Dorajoo, Rajkumar, Lange, Leslie A., Prasad, Gauri, Lorés-Motta, Laura, Pauper, Marc, Long, Jirong, Li, Xiaohui, Theusch, Elizabeth, Takeuchi, Fumihiko, Spracklen, Cassandra N., Loukola, Anu, Bollepalli, Sailalitha, Warner, Sophie C., Wang, Ya Xing, Wei, Wen B., Nutile, Teresa, Ruggiero, Daniela, Sung, Yun Ju, Chen, Shufeng, Liu, Fangchao, Yang, Jingyun, Kentistou, Katherine A., Banas, Bernhard, Nardone, Giuseppe Giovanni, Meidtner, Karina, Bielak, Lawrence F., Smith, Jennifer A., Hebbar, Prashantha, Farmaki, Aliki-Eleni, Hofer, Edith, Lin, Maoxuan, Concas, Maria Pina, Vaccargiu, Simona, van der Most, Peter J., Pitkänen, Niina, Cade, Brian E., van der Laan, Sander W., Chitrala, Kumaraswamy Naidu, Weiss, Stefan, Bentley, Amy R., Doumatey, Ayo P., Adeyemo, Adebowale A., Lee, Jong Young, Petersen, Eva R. B., Nielsen, Aneta A., Choi, Hyeok Sun, Nethander, Maria, Freitag-Wolf, Sandra, Southam, Lorraine, Rayner, Nigel W., Wang, Carol A., Lin, Shih-Yi, Wang, Jun-Sing, Couture, Christian, Lyytikäinen, Leo-Pekka, Nikus, Kjell, Cuellar-Partida, Gabriel, Vestergaard, Henrik, Hidalgo, Bertha, Giannakopoulou, Olga, Cai, Qiuyin, Obura, Morgan O., van Setten, Jessica, Li, Xiaoyin, Liang, Jingjing, Tang, Hua, Terzikhan, Natalie, Shin, Jae Hun, Jackson, Rebecca D., Reiner, Alexander P., Martin, Lisa Warsinger, Chen, Zhengming, Li, Liming, Kawaguchi, Takahisa, Thiery, Joachim, Bis, Joshua C., Launer, Lenore J., Li, Huaixing, Nalls, Mike A., Raitakari, Olli T., Ichihara, Sahoko, Wild, Sarah H., Nelson, Christopher P., Campbell, Harry, Jäger, Susanne, Nabika, Toru, Al-Mulla, Fahd, Niinikoski, Harri, Braund, Peter S., Kolcic, Ivana, Kovacs, Peter, Giardoglou, Tota, Katsuya, Tomohiro, de Kleijn, Dominique, de Borst, Gert J., Kim, Eung Kweon, Adams, Hieab H. H., Ikram, M. Arfan, Zhu, Xiaofeng, Asselbergs, Folkert W., Kraaijeveld, Adriaan O., Beulens, Joline W. J., Shu, Xiao-Ou, Rallidis, Loukianos S., Pedersen, Oluf, Hansen, Torben, Mitchell, Paul, Hewitt, Alex W., Kähönen, Mika, Pérusse, Louis, Bouchard, Claude, Tönjes, Anke, Chen, Yii-Der Ida, Pennell, Craig E., Mori, Trevor A., Lieb, Wolfgang, Franke, Andre, Ohlsson, Claes, Mellström, Dan, Cho, Yoon Shin, Lee, Hyejin, Yuan, Jian-Min, Koh, Woon-Puay, Rhee, Sang Youl, Woo, Jeong-Taek, Heid, Iris M., Stark, Klaus J., Zimmermann, Martina E., Völzke, Henry, Homuth, Georg, Evans, Michele K., Zonderman, Alan B., Polasek, Ozren, Pasterkamp, Gerard, Hoefer, Imo E., Redline, Susan, Pahkala, Katja, Oldehinkel, Albertine J., Snieder, Harold, Biino, Ginevra, Schmidt, Reinhold, Schmidt, Helena, Bandinelli, Stefania, Dedoussis, George, Thanaraj, Thangavel Alphonse, Kardia, Sharon L. R., Peyser, Patricia A., Kato, Norihiro, Schulze, Matthias B., Girotto, Giorgia, Böger, Carsten A., Jung, Bettina, Joshi, Peter K., Bennett, David A., De Jager, Philip L., Lu, Xiangfeng, Mamakou, Vasiliki, Brown, Morris, Caulfield, Mark J., Munroe, Patricia B., Guo, Xiuqing, Ciullo, Marina, Jonas, Jost B., Samani, Nilesh J., Kaprio, Jaakko, Pajukanta, Päivi, Tusié-Luna, Teresa, Aguilar-Salinas, Carlos A., Adair, Linda S., Bechayda, Sonny Augustin, de Silva, H. Janaka, Wickremasinghe, Ananda R., Krauss, Ronald M., Wu, Jer-Yuarn, Zheng, Wei, Hollander, Anneke Iden, Bharadwaj, Dwaipayan, Correa, Adolfo, Wilson, James G., Lind, Lars, Heng, Chew-Kiat, Nelson, Amanda E., Golightly, Yvonne M., Wilson, James F., Penninx, Brenda, Kim, Hyung-Lae, Attia, John, Scott, Rodney J., Rao, D. C., Arnett, Donna K., Hunt, Steven C., Walker, Mark, Koistinen, Heikki A., Chandak, Giriraj R., Mercader, Josep M., Costanzo, Maria C., Jang, Dongkeun, Burtt, Noël P., Villalpando, Clicerio Gonzalez, Orozco, Lorena, Fornage, Myriam, Tai, EShyong, van Dam, Rob M., Lehtimäki, Terho, Chaturvedi, Nish, Yokota, Mitsuhiro, Liu, Jianjun, Reilly, Dermot F., McKnight, Amy Jayne, Kee, Frank, Jöckel, Karl-Heinz, McCarthy, Mark I., Palmer, Colin N. A., Vitart, Veronique, Hayward, Caroline, Simonsick, Eleanor, van Duijn, Cornelia M., Jin, Zi-Bing, Qu, Jia, Hishigaki, Haretsugu, Lin, Xu, März, Winfried, Gudnason, Vilmundur, Tardif, Jean-Claude, Lettre, Guillaume, Hart, Leen M.‘t, Elders, Petra J. M., Damrauer, Scott M., Kumari, Meena, Kivimaki, Mika, van der Harst, Pim, Spector, Tim D., Loos, Ruth J. F., Province, Michael A., Parra, Esteban J., Cruz, Miguel, Psaty, Bruce M., Brandslund, Ivan, Pramstaller, Peter P., Rotimi, Charles N., Christensen, Kaare, Ripatti, Samuli, Widén, Elisabeth, Hakonarson, Hakon, Grant, Struan F. A., Kiemeney, Lambertus A. L. M., de Graaf, Jacqueline, Loeffler, Markus, Kronenberg, Florian, Gu, Dongfeng, Erdmann, Jeanette, Schunkert, Heribert, Franks, Paul W., Linneberg, Allan, Jukema, J. Wouter, Khera, Amit V., Männikkö, Minna, Jarvelin, Marjo-Riitta, Kutalik, Zoltan, Francesco, Cucca, Mook-Kanamori, Dennis O., van Dijk, Ko Willems, Watkins, Hugh, Strachan, David P., Grarup, Niels, Sever, Peter, Poulter, Neil, Chuang, Lee-Ming, Rotter, Jerome I., Dantoft, Thomas M., Karpe, Fredrik, Neville, Matt J., Timpson, Nicholas J., Cheng, Ching-Yu, Wong, Tien-Yin, Khor, Chiea Chuen, Li, Hengtong, Sabanayagam, Charumathi, Peters, Annette, Gieger, Christian, Hattersley, Andrew T., Pedersen, Nancy L., Magnusson, Patrik K. E., Boomsma, Dorret I., Willemsen, Allegonda H. M., Cupples, LAdrienne, van Meurs, Joyce B. J., Ghanbari, Mohsen, Gordon-Larsen, Penny, Huang, Wei, Kim, Young Jin, Tabara, Yasuharu, Wareham, Nicholas J., Langenberg, Claudia, Zeggini, Eleftheria, Kuusisto, Johanna, Laakso, Markku, Ingelsson, Erik, Abecasis, Goncalo, Chambers, John C., Kooner, Jaspal S., de Vries, Paul S., Morrison, Alanna C., Hazelhurst, Scott, Ramsay, Michèle, North, Kari E., Daviglus, Martha, Kraft, Peter, Martin, Nicholas G., Whitfield, John B., Abbas, Shahid, Saleheen, Danish, Walters, Robin G., Holmes, Michael V., Black, Corri, Smith, Blair H., Baras, Aris, Justice, Anne E., Buring, Julie E., Ridker, Paul M., Chasman, Daniel I., Kooperberg, Charles, Tamiya, Gen, Yamamoto, Masayuki, van Heel, David A., Trembath, Richard C., Wei, Wei-Qi, Jarvik, Gail P., Namjou, Bahram, Hayes, M. Geoffrey, Ritchie, Marylyn D., Jousilahti, Pekka, Salomaa, Veikko, Hveem, Kristian, Åsvold, Bjørn Olav, Kubo, Michiaki, Kamatani, Yoichiro, Okada, Yukinori, Murakami, Yoshinori, Kim, Bong-Jo, Thorsteinsdottir, Unnur, Stefansson, Kari, Zhang, Jifeng, Chen, YEugene, Ho, Yuk-Lam, Lynch, Julie A., Rader, Daniel J., Tsao, Philip S., Chang, Kyong-Mi, Cho, Kelly, O’Donnell, Christopher J., Gaziano, John M., Wilson, Peter W. F., Frayling, Timothy M., Hirschhorn, Joel N., Kathiresan, Sekar, Mohlke, Karen L., Sun, Yan V., Morris, Andrew P., Boehnke, Michael, Brown, Christopher D., Natarajan, Pradeep, Deloukas, Panos, Willer, Cristen J., Assimes, Themistocles L., and Peloso, Gina M.
- Abstract
Additional file 6: Figure S2. Frequency distribution of the lipid-related publications for both high confidence genes and the baseline genes.
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- Full Text
- View/download PDF
39. Additional file 9 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
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Kanoni, Stavroula, Graham, Sarah E., Wang, Yuxuan, Surakka, Ida, Ramdas, Shweta, Zhu, Xiang, Clarke, Shoa L., Bhatti, Konain Fatima, Vedantam, Sailaja, Winkler, Thomas W., Locke, Adam E., Marouli, Eirini, Zajac, Greg J. M., Wu, Kuan-Han H., Ntalla, Ioanna, Hui, Qin, Klarin, Derek, Hilliard, Austin T., Wang, Zeyuan, Xue, Chao, Thorleifsson, Gudmar, Helgadottir, Anna, Gudbjartsson, Daniel F., Holm, Hilma, Olafsson, Isleifur, Hwang, Mi Yeong, Han, Sohee, Akiyama, Masato, Sakaue, Saori, Terao, Chikashi, Kanai, Masahiro, Zhou, Wei, Brumpton, Ben M., Rasheed, Humaira, Havulinna, Aki S., Veturi, Yogasudha, Pacheco, Jennifer Allen, Rosenthal, Elisabeth A., Lingren, Todd, Feng, QiPing, Kullo, Iftikhar J., Narita, Akira, Takayama, Jun, Martin, Hilary C., Hunt, Karen A., Trivedi, Bhavi, Haessler, Jeffrey, Giulianini, Franco, Bradford, Yuki, Miller, Jason E., Campbell, Archie, Lin, Kuang, Millwood, Iona Y., Rasheed, Asif, Hindy, George, Faul, Jessica D., Zhao, Wei, Weir, David R., Turman, Constance, Huang, Hongyan, Graff, Mariaelisa, Choudhury, Ananyo, Sengupta, Dhriti, Mahajan, Anubha, Brown, Michael R., Zhang, Weihua, Yu, Ketian, Schmidt, Ellen M., Pandit, Anita, Gustafsson, Stefan, Yin, Xianyong, Luan, Jian’an, Zhao, Jing-Hua, Matsuda, Fumihiko, Jang, Hye-Mi, Yoon, Kyungheon, Medina-Gomez, Carolina, Pitsillides, Achilleas, Hottenga, Jouke Jan, Wood, Andrew R., Ji, Yingji, Gao, Zishan, Haworth, Simon, Yousri, Noha A., Mitchell, Ruth E., Chai, Jin Fang, Aadahl, Mette, Bjerregaard, Anne A., Yao, Jie, Manichaikul, Ani, Hwu, Chii-Min, Hung, Yi-Jen, Warren, Helen R., Ramirez, Julia, Bork-Jensen, Jette, Kårhus, Line L., Goel, Anuj, Sabater-Lleal, Maria, Noordam, Raymond, Mauro, Pala, Matteo, Floris, McDaid, Aaron F., Marques-Vidal, Pedro, Wielscher, Matthias, Trompet, Stella, Sattar, Naveed, Møllehave, Line T., Munz, Matthias, Zeng, Lingyao, Huang, Jianfeng, Yang, Bin, Poveda, Alaitz, Kurbasic, Azra, Lamina, Claudia, Forer, Lukas, Scholz, Markus, Galesloot, Tessel E., Bradfield, Jonathan P., Ruotsalainen, Sanni E., Daw, EWarwick, Zmuda, Joseph M., Mitchell, Jonathan S., Fuchsberger, Christian, Christensen, Henry, Brody, Jennifer A., Vazquez-Moreno, Miguel, Feitosa, Mary F., Wojczynski, Mary K., Wang, Zhe, Preuss, Michael H., Mangino, Massimo, Christofidou, Paraskevi, Verweij, Niek, Benjamins, Jan W., Engmann, Jorgen, Tsao, Noah L., Verma, Anurag, Slieker, Roderick C., Lo, Ken Sin, Zilhao, Nuno R., Le, Phuong, Kleber, Marcus E., Delgado, Graciela E., Huo, Shaofeng, Ikeda, Daisuke D., Iha, Hiroyuki, Yang, Jian, Liu, Jun, Demirkan, Ayşe, Leonard, Hampton L., Marten, Jonathan, Frank, Mirjam, Schmidt, Börge, Smyth, Laura J., Cañadas-Garre, Marisa, Wang, Chaolong, Nakatochi, Masahiro, Wong, Andrew, Hutri-Kähönen, Nina, Sim, Xueling, Xia, Rui, Huerta-Chagoya, Alicia, Fernandez-Lopez, Juan Carlos, Lyssenko, Valeriya, Nongmaithem, Suraj S., Bayyana, Swati, Stringham, Heather M., Irvin, Marguerite R., Oldmeadow, Christopher, Kim, Han-Na, Ryu, Seungho, Timmers, Paul R. H. J., Arbeeva, Liubov, Dorajoo, Rajkumar, Lange, Leslie A., Prasad, Gauri, Lorés-Motta, Laura, Pauper, Marc, Long, Jirong, Li, Xiaohui, Theusch, Elizabeth, Takeuchi, Fumihiko, Spracklen, Cassandra N., Loukola, Anu, Bollepalli, Sailalitha, Warner, Sophie C., Wang, Ya Xing, Wei, Wen B., Nutile, Teresa, Ruggiero, Daniela, Sung, Yun Ju, Chen, Shufeng, Liu, Fangchao, Yang, Jingyun, Kentistou, Katherine A., Banas, Bernhard, Nardone, Giuseppe Giovanni, Meidtner, Karina, Bielak, Lawrence F., Smith, Jennifer A., Hebbar, Prashantha, Farmaki, Aliki-Eleni, Hofer, Edith, Lin, Maoxuan, Concas, Maria Pina, Vaccargiu, Simona, van der Most, Peter J., Pitkänen, Niina, Cade, Brian E., van der Laan, Sander W., Chitrala, Kumaraswamy Naidu, Weiss, Stefan, Bentley, Amy R., Doumatey, Ayo P., Adeyemo, Adebowale A., Lee, Jong Young, Petersen, Eva R. B., Nielsen, Aneta A., Choi, Hyeok Sun, Nethander, Maria, Freitag-Wolf, Sandra, Southam, Lorraine, Rayner, Nigel W., Wang, Carol A., Lin, Shih-Yi, Wang, Jun-Sing, Couture, Christian, Lyytikäinen, Leo-Pekka, Nikus, Kjell, Cuellar-Partida, Gabriel, Vestergaard, Henrik, Hidalgo, Bertha, Giannakopoulou, Olga, Cai, Qiuyin, Obura, Morgan O., van Setten, Jessica, Li, Xiaoyin, Liang, Jingjing, Tang, Hua, Terzikhan, Natalie, Shin, Jae Hun, Jackson, Rebecca D., Reiner, Alexander P., Martin, Lisa Warsinger, Chen, Zhengming, Li, Liming, Kawaguchi, Takahisa, Thiery, Joachim, Bis, Joshua C., Launer, Lenore J., Li, Huaixing, Nalls, Mike A., Raitakari, Olli T., Ichihara, Sahoko, Wild, Sarah H., Nelson, Christopher P., Campbell, Harry, Jäger, Susanne, Nabika, Toru, Al-Mulla, Fahd, Niinikoski, Harri, Braund, Peter S., Kolcic, Ivana, Kovacs, Peter, Giardoglou, Tota, Katsuya, Tomohiro, de Kleijn, Dominique, de Borst, Gert J., Kim, Eung Kweon, Adams, Hieab H. H., Ikram, M. Arfan, Zhu, Xiaofeng, Asselbergs, Folkert W., Kraaijeveld, Adriaan O., Beulens, Joline W. J., Shu, Xiao-Ou, Rallidis, Loukianos S., Pedersen, Oluf, Hansen, Torben, Mitchell, Paul, Hewitt, Alex W., Kähönen, Mika, Pérusse, Louis, Bouchard, Claude, Tönjes, Anke, Chen, Yii-Der Ida, Pennell, Craig E., Mori, Trevor A., Lieb, Wolfgang, Franke, Andre, Ohlsson, Claes, Mellström, Dan, Cho, Yoon Shin, Lee, Hyejin, Yuan, Jian-Min, Koh, Woon-Puay, Rhee, Sang Youl, Woo, Jeong-Taek, Heid, Iris M., Stark, Klaus J., Zimmermann, Martina E., Völzke, Henry, Homuth, Georg, Evans, Michele K., Zonderman, Alan B., Polasek, Ozren, Pasterkamp, Gerard, Hoefer, Imo E., Redline, Susan, Pahkala, Katja, Oldehinkel, Albertine J., Snieder, Harold, Biino, Ginevra, Schmidt, Reinhold, Schmidt, Helena, Bandinelli, Stefania, Dedoussis, George, Thanaraj, Thangavel Alphonse, Kardia, Sharon L. R., Peyser, Patricia A., Kato, Norihiro, Schulze, Matthias B., Girotto, Giorgia, Böger, Carsten A., Jung, Bettina, Joshi, Peter K., Bennett, David A., De Jager, Philip L., Lu, Xiangfeng, Mamakou, Vasiliki, Brown, Morris, Caulfield, Mark J., Munroe, Patricia B., Guo, Xiuqing, Ciullo, Marina, Jonas, Jost B., Samani, Nilesh J., Kaprio, Jaakko, Pajukanta, Päivi, Tusié-Luna, Teresa, Aguilar-Salinas, Carlos A., Adair, Linda S., Bechayda, Sonny Augustin, de Silva, H. Janaka, Wickremasinghe, Ananda R., Krauss, Ronald M., Wu, Jer-Yuarn, Zheng, Wei, Hollander, Anneke Iden, Bharadwaj, Dwaipayan, Correa, Adolfo, Wilson, James G., Lind, Lars, Heng, Chew-Kiat, Nelson, Amanda E., Golightly, Yvonne M., Wilson, James F., Penninx, Brenda, Kim, Hyung-Lae, Attia, John, Scott, Rodney J., Rao, D. C., Arnett, Donna K., Hunt, Steven C., Walker, Mark, Koistinen, Heikki A., Chandak, Giriraj R., Mercader, Josep M., Costanzo, Maria C., Jang, Dongkeun, Burtt, Noël P., Villalpando, Clicerio Gonzalez, Orozco, Lorena, Fornage, Myriam, Tai, EShyong, van Dam, Rob M., Lehtimäki, Terho, Chaturvedi, Nish, Yokota, Mitsuhiro, Liu, Jianjun, Reilly, Dermot F., McKnight, Amy Jayne, Kee, Frank, Jöckel, Karl-Heinz, McCarthy, Mark I., Palmer, Colin N. A., Vitart, Veronique, Hayward, Caroline, Simonsick, Eleanor, van Duijn, Cornelia M., Jin, Zi-Bing, Qu, Jia, Hishigaki, Haretsugu, Lin, Xu, März, Winfried, Gudnason, Vilmundur, Tardif, Jean-Claude, Lettre, Guillaume, Hart, Leen M.‘t, Elders, Petra J. M., Damrauer, Scott M., Kumari, Meena, Kivimaki, Mika, van der Harst, Pim, Spector, Tim D., Loos, Ruth J. F., Province, Michael A., Parra, Esteban J., Cruz, Miguel, Psaty, Bruce M., Brandslund, Ivan, Pramstaller, Peter P., Rotimi, Charles N., Christensen, Kaare, Ripatti, Samuli, Widén, Elisabeth, Hakonarson, Hakon, Grant, Struan F. A., Kiemeney, Lambertus A. L. M., de Graaf, Jacqueline, Loeffler, Markus, Kronenberg, Florian, Gu, Dongfeng, Erdmann, Jeanette, Schunkert, Heribert, Franks, Paul W., Linneberg, Allan, Jukema, J. Wouter, Khera, Amit V., Männikkö, Minna, Jarvelin, Marjo-Riitta, Kutalik, Zoltan, Francesco, Cucca, Mook-Kanamori, Dennis O., van Dijk, Ko Willems, Watkins, Hugh, Strachan, David P., Grarup, Niels, Sever, Peter, Poulter, Neil, Chuang, Lee-Ming, Rotter, Jerome I., Dantoft, Thomas M., Karpe, Fredrik, Neville, Matt J., Timpson, Nicholas J., Cheng, Ching-Yu, Wong, Tien-Yin, Khor, Chiea Chuen, Li, Hengtong, Sabanayagam, Charumathi, Peters, Annette, Gieger, Christian, Hattersley, Andrew T., Pedersen, Nancy L., Magnusson, Patrik K. E., Boomsma, Dorret I., Willemsen, Allegonda H. M., Cupples, LAdrienne, van Meurs, Joyce B. J., Ghanbari, Mohsen, Gordon-Larsen, Penny, Huang, Wei, Kim, Young Jin, Tabara, Yasuharu, Wareham, Nicholas J., Langenberg, Claudia, Zeggini, Eleftheria, Kuusisto, Johanna, Laakso, Markku, Ingelsson, Erik, Abecasis, Goncalo, Chambers, John C., Kooner, Jaspal S., de Vries, Paul S., Morrison, Alanna C., Hazelhurst, Scott, Ramsay, Michèle, North, Kari E., Daviglus, Martha, Kraft, Peter, Martin, Nicholas G., Whitfield, John B., Abbas, Shahid, Saleheen, Danish, Walters, Robin G., Holmes, Michael V., Black, Corri, Smith, Blair H., Baras, Aris, Justice, Anne E., Buring, Julie E., Ridker, Paul M., Chasman, Daniel I., Kooperberg, Charles, Tamiya, Gen, Yamamoto, Masayuki, van Heel, David A., Trembath, Richard C., Wei, Wei-Qi, Jarvik, Gail P., Namjou, Bahram, Hayes, M. Geoffrey, Ritchie, Marylyn D., Jousilahti, Pekka, Salomaa, Veikko, Hveem, Kristian, Åsvold, Bjørn Olav, Kubo, Michiaki, Kamatani, Yoichiro, Okada, Yukinori, Murakami, Yoshinori, Kim, Bong-Jo, Thorsteinsdottir, Unnur, Stefansson, Kari, Zhang, Jifeng, Chen, YEugene, Ho, Yuk-Lam, Lynch, Julie A., Rader, Daniel J., Tsao, Philip S., Chang, Kyong-Mi, Cho, Kelly, O’Donnell, Christopher J., Gaziano, John M., Wilson, Peter W. F., Frayling, Timothy M., Hirschhorn, Joel N., Kathiresan, Sekar, Mohlke, Karen L., Sun, Yan V., Morris, Andrew P., Boehnke, Michael, Brown, Christopher D., Natarajan, Pradeep, Deloukas, Panos, Willer, Cristen J., Assimes, Themistocles L., and Peloso, Gina M.
- Abstract
Additional file 9: Figure S3. Lipid traits – tissue/cell type associations estimated by DESE according to GTEx gene-level and GTEx transcript-level selective expression.
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- 2023
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40. Genetic counselling and testing in pulmonary arterial hypertension: a consensus statement on behalf of the International Consortium for Genetic Studies in PAH
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Eichstaedt, Christina A., primary, Belge, Catharina, additional, Chung, Wendy K., additional, Gräf, Stefan, additional, Grünig, Ekkehard, additional, Montani, David, additional, Quarck, Rozenn, additional, Tenorio-Castano, Jair A., additional, Soubrier, Florent, additional, Trembath, Richard C., additional, and Morrell, Nicholas W., additional
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- 2022
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41. An analysis of IL-36 signature genes and individuals with IL1RL2 knockout mutations validates IL-36 as a psoriasis therapeutic target
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Mahil, Satveer K., Catapano, Marika, Di Meglio, Paola, Dand, Nick, Ahlfors, Helena, Carr, Ian M., Smith, Catherine H., Trembath, Richard C., Peakman, Mark, Wright, John, Ciccarelli, Francesca D., Barker, Jonathan N., and Capon, Francesca
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- 2017
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42. Genetics and Genomics of Pulmonary Arterial Hypertension
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Soubrier, Florent, Chung, Wendy K., Machado, Rajiv, Grünig, Ekkehard, Aldred, Micheala, Geraci, Mark, Loyd, James E., Elliott, C. Gregory, Trembath, Richard C., Newman, John H., and Humbert, Marc
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- 2013
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43. A polygenic resilience score moderates the genetic risk for schizophrenia
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Hess, Jonathan L, Tylee, Daniel S, Mors, Ole, Duan, Jubao, Dudbridge, Frank, Duncanson, Audrey, Durmishi, Naser, Edkins, Sarah, Ehrenreich, Hannelore, Eichhammer, Peter, Eriksson, Johan, Escott-Price, Valentina, Esko, Tõnu, Nordentoft, Merete, Essioux, Laurent, Fanous, Ayman H, Farh, Kai-How, Farrell, Martilias S, Frank, Josef, Franke, Lude, Freedman, Robert, Freeman, Colin, Freimer, Nelson B, Friedl, Marion, Hougaard, David M, Friedman, Joseph I, Fromer, Menachem, Gejman, Pablo V, Genovese, Giulio, Georgieva, Lyudmila, Giannoulatou, Eleni, Giegling, Ina, Gill, Michael, Gillman, Matthew, Giusti-Rodríguez, Paola, Byberg-Grauholm, Jonas, Godard, Stephanie, Goldstein, Jacqueline I, Golimbet, Vera, Gopal, Srihari, Gratten, Jacob, Gray, Emma, Gurling, Hugh, Gwilliam, Rhian, de Haan, Lieuwe, Hall, Jeremy, Bækvad-Hansen, Marie, Hammer, Christian, Hammond, Naomi, Hamshere, Marian L, Hansen, Mark, Hansen, Thomas, Haroutunian, Vahram, Hartmann, Annette M, Hellenthal, Garrett, Henskens, Frans A, Herms, Stefan, Greenwood, Tiffany A, Hirschhorn, Joel N, Hoffmann, Per, Hofman, Andrea, Hollegaard, Mads V, Huang, Hailiang, Hultman, Christina M, Hunt, Sarah E, Ikeda, Masashi, Iwata, Nakao, Iyegbe, Conrad, Tsuang, Ming T, Jablensky, Assen V, Jankowski, Janusz, Jayakumar, Alagurevathi, Joa, Inge, Jönsson, Erik G, Julià, Antonio, Kähler, Anna K, Kahn, René S, Kalaydjieva, Luba, Karachanak-Yankova, Sena, Curtis, David, Karjalainen, Juha, Kavanagh, David, Keller, Matthew C, Kendler, Kenneth S, Kennedy, James L, Khrunin, Andrey, Kim, Yunjung, Kirov, George, Klovins, Janis, Knight, Jo, Steinberg, Stacy, Knowles, James A, Konte, Bettina, Kucinskas, Vaidutis, Kucinskiene, Zita Ausrele, Kuzelova-Ptackova, Hana, Langford, Cordelia, Laurent, Claudine, Lawrie, Stephen, Lee, S Hong, Lee, Phil, Sigurdsson, Engilbert, Lee, Jimmy, Legge, Sophie E, Lencz, Todd, Lerer, Bernard, Levinson, Douglas F, Lewis, Cathryn M, Li, Tao, Li, Qingqin S, Li, Miaoxin, Liang, Kung-Yee, Mattheisen, Manuel, Stefánsson, Hreinn, Liddle, Jennifer, Lieberman, Jeffrey, Limborska, Svetlana, Lin, Kuang, Linszen, Don H, Liu, Jianjun, Lönnqvist, Jouko, Loughland, Carmel M, Lubinski, Jan, Macek, Milan, Stefánsson, Kári, Magnusson, Patrik K E, Maher, Brion S, Maier, Wolfgang, Malhotra, Anil K, Mallet, Jacques, Markus, Hugh S, Marsal, Sara, Mata, Ignacio, Mathew, Christopher G, Mattingsdal, Morten, Edenberg, Howard J, McCann, Owen T, McCarley, Robert W, McCarroll, Steven A, McCarthy, Mark I, McDonald, Colm, McIntosh, Andrew M, McQuillin, Andrew, Meier, Sandra, Meijer, Carin J, Melegh, Bela, Holmans, Peter, Melle, Ingrid, Mesholam-Gately, Raquelle I, Metspalu, Andres, Michie, Patricia T, Milani, Lili, Milanova, Vihra, Mokrab, Younes, Moran, Jennifer L, Morris, Derek W, Mowry, Bryan J, Faraone, Stephen V, Müller-Myhsok, Bertram, Murphy, Kieran C, Murray, Robin M, Myin-Germeys, Inez, Neale, Benjamin M, Nelis, Mari, Nenadic, Igor, Nertney, Deborah A, Nestadt, Gerald, Nicodemus, Kristin K, Glatt, Stephen J, Nikitina-Zake, Liene, Nisenbaum, Laura, Nordin, Annelie, Nöthen, Markus M, O'Callaghan, Eadbhard, O'Donovan, Michael C, O'Dushlaine, Colm, O'Neill, F Anthony, Oh, Sang-Yun, Olincy, Ann, Adolfsson, Rolf, Olsen, Line, Ophoff, Roel A, Van Os, Jim, Owen, Michael J, Palmer, Colin N A, Palotie, Aarno, Pantelis, Christos, Papadimitriou, George N, Papiol, Sergi, Parkhomenko, Elena, Agartz, Ingrid, Pato, Michele T, Pato, Carlos N, Paunio, Tiina, Pearson, Richard, Cairns, Murray J, DeLisi, Lynn E, Gershon, Elliot S, Kelly, Brian J, Lam, Max, Norgren, Nina, Agerbo, Esben, Paciga, Sara A, Tooney, Paul A, Wu, Jing Qin, Pejovic-Milovancevic, Milica, Perkins, Diana O, Pers, Tune H, Petryshen, Tracey L, Pietiläinen, Olli, Pimm, Jonathan, Pirinen, Matti, Albus, Margot, Plomin, Robert, Pocklington, Andrew J, Posthuma, Danielle, Potter, Simon C, Powell, John, Price, Alkes, Pulver, Ann E, Purcell, Shaun M, Quested, Digby, Rasmussen, Henrik B, Consortium, Schizophrenia Working Group of the Psychiatric Genomics, Alexander, Madeline, Rautanen, Anna, Ravindrarajah, Radhi, Reichenberg, Abraham, Reimers, Mark A, Richards, Alexander L, Ricketts, Michelle, Rietschel, Marcella, Riley, Brien P, Ripke, Stephan, Roffman, Joshua L, Amin, Farooq, Roussos, Panos, Ruderfer, Douglas M, Rujescu, Dan, Salomaa, Veikko, Sanders, Alan R, Sawcer, Stephen J, Schall, Ulrich, Schubert, Christian R, Schulze, Thomas G, Schwab, Sibylle G, Andreassen, Ole A, Scolnick, Edward M, Scott, Rodney J, Seidman, Larry J, Sham, Pak C, Shi, Jianxin, Silagadze, Teimuraz, Silverman, Jeremy M, Sim, Kang, Sklar, Pamela, Arranz, Maria J, Slominsky, Petr, Smoller, Jordan W, So, Hon-Cheong, Söderman, Erik, Spencer, Chris C A, Clair, David St, Stahl, Eli A, Stogmann, Elisabeth, Strange, Amy, Straub, Richard E, Bacanu, Silviu A, Strengman, Eric, Strohmaier, Jana, Stroup, T Scott, Su, Zhan, Subramaniam, Mythily, Sullivan, Patrick F, Suvisaari, Jaana, Svrakic, Dragan M, Szatkiewicz, Jin P, Tashakkori-Ghanbaria, Avazeh, Bakker, Steven, Thirumalai, Srinivas, Toncheva, Draga, Tosato, Sarah, Trembath, Richard C, Veijola, Juha, Visscher, Peter M, Viswanathan, Ananth C, Vukcevic, Damjan, Waddington, John, Waller, Matthew, Band, Gavin, Walsh, Dermot, Walshe, Muriel, Walters, James T R, Wang, Qiang, Wang, Dai, Webb, Bradley T, Weinberger, Daniel R, Weisbrod, Matthias, Weiser, Mark, Wendland, Jens R, Barroso, Ines, Weston, Paul, Whittaker, Pamela, Widaa, Sara, Wiersma, Durk, Wildenauer, Dieter B, Williams, Stephanie, Williams, Nigel M, Witt, Stephanie H, Wolen, Aaron R, Wong, Emily H M, Begemann, Martin, Wood, Nicholas W, Wormley, Brandon K, Wray, Naomi R, Xi, Hualin Simon, Zai, Clement C, Zheng, Xuebin, Zimprich, Fritz, Bellenguez, Céline, Research, Lundbeck Foundation Initiative for Integrative Psychiatric, Belliveau, Richard A, Bender, Stephan, Bene, Judit, Bergen, Sarah E, Bevilacqua, Elizabeth, Bigdeli, Tim B, Black, Donald W, Blackburn, Hannah, Blackwell, Jenefer M, Blackwood, Douglas H R, Børglum, Anders D, Bramon, Elvira, Brown, Matthew A, Bruggeman, Richard, Buccola, Nancy G, Buckner, Randy L, Bulik-Sullivan, Brendan, Bumpstead, Suzannah J, Buxbaum, Joseph D, Byerley, William, Cahn, Wiepke, Als, Thomas D, Cai, Guiqing, Campion, Dominique, Cantor, Rita M, Carr, Vaughan J, Carrera, Noa, Casas, Juan P, Catts, Stanley V, Chambert, Kimberley D, Chan, Ronald Y L, Chan, Raymond C K, Grove, Jakob, Chen, Eric Y H, Cheng, Wei, Cheung, Eric F C, Chong, Siow Ann, Cichon, Sven, Cloninger, C Robert, Cohen, David, Cohen, Nadine, Collier, David A, Cormican, Paul, Werge, Thomas, Corvin, Aiden, Craddock, Nick, Crespo-Facorro, Benedicto, Crowley, James J, Daly, Mark J, Darvasi, Ariel, Davidson, Michael, Davis, Kenneth L, Degenhardt, Franziska, Del Favero, Jurgen, Mortensen, Preben Bo, Deloukas, Panos, Demontis, Ditte, Dikeos, Dimitris, Dinan, Timothy, Djurovic, Srdjan, Domenici, Enrico, Donnelly, Peter, Donohoe, Gary, Drapeau, Elodie, Dronov, Serge, Læknadeild (HÍ), Faculty of Medicine (UI), Heilbrigðisvísindasvið (HÍ), School of Health Sciences (UI), Háskóli Íslands, University of Iceland, Adult Psychiatry, ANS - Complex Trait Genetics, ANS - Mood, Anxiety, Psychosis, Stress & Sleep, APH - Mental Health, Hess, Jonathan L, Tylee, Daniel S, Mattheisen, Manuel, Borglum, Anders D, Glatt, Stephen J, Lee, Sand Hong, Schizophrenia Working Group of thePsychiatric Genomics Consortium, Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Amsterdam Neuroscience - Complex Trait Genetics, Complex Trait Genetics, and Myin-Germeys, Inez
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Multifactorial Inheritance ,Schizophrenia/genetics ,Genome-wide association study ,Disease ,Medical and Health Sciences ,0302 clinical medicine ,Risk Factors ,schizophrenia, genetics, risk ,2.1 Biological and endogenous factors ,genetics ,polygenic score ,Aetiology ,genome wide association study ,risk ,Genetics ,Psychiatry ,0303 health sciences ,Schizophrenia Working Group of the Psychiatric Genomics Consortium ,Genetic Predisposition to Disease/genetics ,Single Nucleotide ,Genomics ,Biological Sciences ,Serious Mental Illness ,Polymorphism, Single Nucleotide/genetics ,Penetrance ,3. Good health ,Psychiatry and Mental health ,Mental Health ,Mendelian disease ,Erfðarannsóknir ,Life Sciences & Biomedicine ,Single Nucleotide/genetics ,Biochemistry & Molecular Biology ,Schizophrenia (object-oriented programming) ,high risk ,Biology ,Polymorphism, Single Nucleotide ,Article ,03 medical and health sciences ,Cellular and Molecular Neuroscience ,Geðklofi ,Humans ,Genetic Predisposition to Disease ,ddc:610 ,Allele ,Polymorphism ,Resilience (network) ,Molecular Biology ,resilience ,Multifactorial Inheritance/genetics ,Alleles ,030304 developmental biology ,Science & Technology ,Prevention ,Human Genome ,Psychology and Cognitive Sciences ,Neurosciences ,Brain Disorders ,Lundbeck Foundation Initiative for Integrative Psychiatric Research ,schizophrenia ,Good Health and Well Being ,Schizophrenia ,Neurosciences & Neurology ,030217 neurology & neurosurgery ,Genome-Wide Association Study - Abstract
Publisher's version (útgefin grein), Based on the discovery by the Resilience Project (Chen R. et al. Nat Biotechnol 34:531–538, 2016) of rare variants that confer resistance to Mendelian disease, and protective alleles for some complex diseases, we posited the existence of genetic variants that promote resilience to highly heritable polygenic disorders1,0 such as schizophrenia. Resilience has been traditionally viewed as a psychological construct, although our use of the term resilience refers to a different construct that directly relates to the Resilience Project, namely: heritable variation that promotes resistance to disease by reducing the penetrance of risk loci, wherein resilience and risk loci operate orthogonal to one another. In this study, we established a procedure to identify unaffected individuals with relatively high polygenic risk for schizophrenia, and contrasted them with risk-matched schizophrenia cases to generate the first known “polygenic resilience score” that represents the additive contributions to SZ resistance by variants that are distinct from risk loci. The resilience score was derived from data compiled by the Psychiatric Genomics Consortium, and replicated in three independent samples. This work establishes a generalizable framework for finding resilience variants for any complex, heritable disorder., SJG is supported by grants from the U.S. National Institutes of Health (5R01MH101519, 5R01AG054002), the Sidney R. Baer, Jr. Foundation, and NARSAD: The Brain & Behavior Research Foundation. SVF is supported by the K.G. Jebsen Centre for Research on Neuropsychiatric Disorders, University of Bergen, Bergen, Norway, the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement number 602805, the European Union’s Horizon 2020 research and innovation programme under grant agreement number 667302 and NIMH grants 5R01MH101519 and U01 MH109536-01. HJE is supported by grants from the U.S. National Institutes of Health (U10 AA008401; U01 MH109532). Statistical analyses were conducted on the Genetic Cluster Computer, which is financially supported by the Netherlands Scientific Organization (NOW; 480-05-003) along with a supplement from the Dutch Brain Foundation and VU University. The Danish iPSYCH (The Lundbeck Foundation Initiative for Integrative Psychiatric Research) and GEMS2 teams acknowledge funding from The Lundbeck Foundation (grant no R102-A9118 and R155-2014-1724), the Stanley Medical Research Institute, an Advanced Grant from the European Research Council (project no: 294838), the Danish Strategic Research Council and grants from Aarhus University to the iSEQ and CIRRAU centers. The Danish National Biobank resource at Statens Serum Institut was supported by the Novo Nordisk Foundation. Computational resources for handling and statistical analysis of iPSYCH data on the GenomeDK HPC facility were provided by the iSEQ center, Aarhus University, Denmark (grant to ADB).
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- 2021
44. Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
- Author
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CDL Onderzoek Pasterkamp, Circulatory Health, Onderzoek Precision medicine, Zorgeenheid Vaatchirurgie Medisch, Infection & Immunity, Regenerative Medicine and Stem Cells, Team Medisch, Cardiovasculaire Epi Team 1, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Centraal Diagnostisch Laboratorium, Gezonde Vaten, Kanoni, Stavroula, Graham, Sarah E, Wang, Yuxuan, Surakka, Ida, Ramdas, Shweta, Zhu, Xiang, Clarke, Shoa L, Bhatti, Konain Fatima, Vedantam, Sailaja, Winkler, Thomas W, Locke, Adam E, Marouli, Eirini, Zajac, Greg J M, Wu, Kuan-Han H, Ntalla, Ioanna, Hui, Qin, Klarin, Derek, Hilliard, Austin T, Wang, Zeyuan, Xue, Chao, Thorleifsson, Gudmar, Helgadottir, Anna, Gudbjartsson, Daniel F, Holm, Hilma, Olafsson, Isleifur, Hwang, Mi Yeong, Han, Sohee, Akiyama, Masato, Sakaue, Saori, Terao, Chikashi, Kanai, Masahiro, Zhou, Wei, Brumpton, Ben M, Rasheed, Humaira, Havulinna, Aki S, Veturi, Yogasudha, Pacheco, Jennifer Allen, Rosenthal, Elisabeth A, Lingren, Todd, Feng, QiPing, Kullo, Iftikhar J, Narita, Akira, Takayama, Jun, Martin, Hilary C, Hunt, Karen A, Trivedi, Bhavi, Haessler, Jeffrey, Giulianini, Franco, Bradford, Yuki, Miller, Jason E, Campbell, Archie, Lin, Kuang, Millwood, Iona Y, Rasheed, Asif, Hindy, George, Faul, Jessica D, Zhao, Wei, Weir, David R, Turman, Constance, Huang, Hongyan, Graff, Mariaelisa, Choudhury, Ananyo, Sengupta, Dhriti, Mahajan, Anubha, Brown, Michael R, Zhang, Weihua, Yu, Ketian, Schmidt, Ellen M, Pandit, Anita, Gustafsson, Stefan, Yin, Xianyong, Luan, Jian'an, Zhao, Jing-Hua, Matsuda, Fumihiko, Jang, Hye-Mi, Yoon, Kyungheon, Medina-Gomez, Carolina, Pitsillides, Achilleas, Hottenga, Jouke Jan, Wood, Andrew R, Ji, Yingji, Gao, Zishan, Haworth, Simon, Yousri, Noha A, Mitchell, Ruth E, Chai, Jin Fang, Aadahl, Mette, Bjerregaard, Anne A, Yao, Jie, Manichaikul, Ani, Hwu, Chii-Min, Hung, Yi-Jen, Warren, Helen R, Ramirez, Julia, Bork-Jensen, Jette, Kårhus, Line L, Goel, Anuj, Sabater-Lleal, Maria, Noordam, Raymond, Mauro, Pala, Matteo, Floris, McDaid, Aaron F, Marques-Vidal, Pedro, Wielscher, Matthias, Trompet, Stella, Sattar, Naveed, Møllehave, Line T, Munz, Matthias, Zeng, Lingyao, Huang, Jianfeng, Yang, Bin, Poveda, Alaitz, Kurbasic, Azra, Lamina, Claudia, Forer, Lukas, Scholz, Markus, Galesloot, Tessel E, Bradfield, Jonathan P, Ruotsalainen, Sanni E, Daw, EWarwick, Zmuda, Joseph M, Mitchell, Jonathan S, Fuchsberger, Christian, Christensen, Henry, Brody, Jennifer A, Vazquez-Moreno, Miguel, Feitosa, Mary F, Wojczynski, Mary K, Wang, Zhe, Preuss, Michael H, Mangino, Massimo, Christofidou, Paraskevi, Verweij, Niek, Benjamins, Jan W, Engmann, Jorgen, Tsao, Noah L, Verma, Anurag, Slieker, Roderick C, Lo, Ken Sin, Zilhao, Nuno R, Le, Phuong, Kleber, Marcus E, Delgado, Graciela E, Huo, Shaofeng, Ikeda, Daisuke D, Iha, Hiroyuki, Yang, Jian, Liu, Jun, Demirkan, Ayşe, Leonard, Hampton L, Marten, Jonathan, Frank, Mirjam, Schmidt, Börge, Smyth, Laura J, Cañadas-Garre, Marisa, Wang, Chaolong, Nakatochi, Masahiro, Wong, Andrew, Hutri-Kähönen, Nina, Sim, Xueling, Xia, Rui, Huerta-Chagoya, Alicia, Fernandez-Lopez, Juan Carlos, Lyssenko, Valeriya, Nongmaithem, Suraj S, Bayyana, Swati, Stringham, Heather M, Irvin, Marguerite R, Oldmeadow, Christopher, Kim, Han-Na, Ryu, Seungho, Timmers, Paul R H J, Arbeeva, Liubov, Dorajoo, Rajkumar, Lange, Leslie A, Prasad, Gauri, Lorés-Motta, Laura, Pauper, Marc, Long, Jirong, Li, Xiaohui, Theusch, Elizabeth, Takeuchi, Fumihiko, Spracklen, Cassandra N, Loukola, Anu, Bollepalli, Sailalitha, Warner, Sophie C, Wang, Ya Xing, Wei, Wen B, Nutile, Teresa, Ruggiero, Daniela, Sung, Yun Ju, Chen, Shufeng, Liu, Fangchao, Yang, Jingyun, Kentistou, Katherine A, Banas, Bernhard, Nardone, Giuseppe Giovanni, Meidtner, Karina, Bielak, Lawrence F, Smith, Jennifer A, Hebbar, Prashantha, Farmaki, Aliki-Eleni, Hofer, Edith, Lin, Maoxuan, Concas, Maria Pina, Vaccargiu, Simona, van der Most, Peter J, Pitkänen, Niina, Cade, Brian E, van der Laan, Sander W, Chitrala, Kumaraswamy Naidu, Weiss, Stefan, Bentley, Amy R, Doumatey, Ayo P, Adeyemo, Adebowale A, Lee, Jong Young, Petersen, Eva R B, Nielsen, Aneta A, Choi, Hyeok Sun, Nethander, Maria, Freitag-Wolf, Sandra, Southam, Lorraine, Rayner, Nigel W, Wang, Carol A, Lin, Shih-Yi, Wang, Jun-Sing, Couture, Christian, Lyytikäinen, Leo-Pekka, Nikus, Kjell, Cuellar-Partida, Gabriel, Vestergaard, Henrik, Hidalgo, Bertha, Giannakopoulou, Olga, Cai, Qiuyin, Obura, Morgan O, van Setten, Jessica, Li, Xiaoyin, Liang, Jingjing, Tang, Hua, Terzikhan, Natalie, Shin, Jae Hun, Jackson, Rebecca D, Reiner, Alexander P, Martin, Lisa Warsinger, Chen, Zhengming, Li, Liming, Kawaguchi, Takahisa, Thiery, Joachim, Bis, Joshua C, Launer, Lenore J, Li, Huaixing, Nalls, Mike A, Raitakari, Olli T, Ichihara, Sahoko, Wild, Sarah H, Nelson, Christopher P, Campbell, Harry, Jäger, Susanne, Nabika, Toru, Al-Mulla, Fahd, Niinikoski, Harri, Braund, Peter S, Kolcic, Ivana, Kovacs, Peter, Giardoglou, Tota, Katsuya, Tomohiro, de Kleijn, Dominique, de Borst, Gert J, Kim, Eung Kweon, Adams, Hieab H H, Ikram, M Arfan, Zhu, Xiaofeng, Asselbergs, Folkert W, Kraaijeveld, Adriaan O, Beulens, Joline W J, Shu, Xiao-Ou, Rallidis, Loukianos S, Pedersen, Oluf, Hansen, Torben, Mitchell, Paul, Hewitt, Alex W, Kähönen, Mika, Pérusse, Louis, Bouchard, Claude, Tönjes, Anke, Chen, Yii-Der Ida, Pennell, Craig E, Mori, Trevor A, Lieb, Wolfgang, Franke, Andre, Ohlsson, Claes, Mellström, Dan, Cho, Yoon Shin, Lee, Hyejin, Yuan, Jian-Min, Koh, Woon-Puay, Rhee, Sang Youl, Woo, Jeong-Taek, Heid, Iris M, Stark, Klaus J, Zimmermann, Martina E, Völzke, Henry, Homuth, Georg, Evans, Michele K, Zonderman, Alan B, Polasek, Ozren, Pasterkamp, Gerard, Hoefer, Imo E, Redline, Susan, Pahkala, Katja, Oldehinkel, Albertine J, Snieder, Harold, Biino, Ginevra, Schmidt, Reinhold, Schmidt, Helena, Bandinelli, Stefania, Dedoussis, George, Thanaraj, Thangavel Alphonse, Kardia, Sharon L R, Peyser, Patricia A, Kato, Norihiro, Schulze, Matthias B, Girotto, Giorgia, Böger, Carsten A, Jung, Bettina, Joshi, Peter K, Bennett, David A, De Jager, Philip L, Lu, Xiangfeng, Mamakou, Vasiliki, Brown, Morris, Caulfield, Mark J, Munroe, Patricia B, Guo, Xiuqing, Ciullo, Marina, Jonas, Jost B, Samani, Nilesh J, Kaprio, Jaakko, Pajukanta, Päivi, Tusié-Luna, Teresa, Aguilar-Salinas, Carlos A, Adair, Linda S, Bechayda, Sonny Augustin, de Silva, H Janaka, Wickremasinghe, Ananda R, Krauss, Ronald M, Wu, Jer-Yuarn, Zheng, Wei, Hollander, Anneke Iden, Bharadwaj, Dwaipayan, Correa, Adolfo, Wilson, James G, Lind, Lars, Heng, Chew-Kiat, Nelson, Amanda E, Golightly, Yvonne M, Wilson, James F, Penninx, Brenda, Kim, Hyung-Lae, Attia, John, Scott, Rodney J, Rao, D C, Arnett, Donna K, Hunt, Steven C, Walker, Mark, Koistinen, Heikki A, Chandak, Giriraj R, Mercader, Josep M, Costanzo, Maria C, Jang, Dongkeun, Burtt, Noël P, Villalpando, Clicerio Gonzalez, Orozco, Lorena, Fornage, Myriam, Tai, EShyong, van Dam, Rob M, Lehtimäki, Terho, Chaturvedi, Nish, Yokota, Mitsuhiro, Liu, Jianjun, Reilly, Dermot F, McKnight, Amy Jayne, Kee, Frank, Jöckel, Karl-Heinz, McCarthy, Mark I, Palmer, Colin N A, Vitart, Veronique, Hayward, Caroline, Simonsick, Eleanor, van Duijn, Cornelia M, Jin, Zi-Bing, Qu, Jia, Hishigaki, Haretsugu, Lin, Xu, März, Winfried, Gudnason, Vilmundur, Tardif, Jean-Claude, Lettre, Guillaume, Hart, Leen M 't, Elders, Petra J M, Damrauer, Scott M, Kumari, Meena, Kivimaki, Mika, van der Harst, Pim, Spector, Tim D, Loos, Ruth J F, Province, Michael A, Parra, Esteban J, Cruz, Miguel, Psaty, Bruce M, Brandslund, Ivan, Pramstaller, Peter P, Rotimi, Charles N, Christensen, Kaare, Ripatti, Samuli, Widén, Elisabeth, Hakonarson, Hakon, Grant, Struan F A, Kiemeney, Lambertus A L M, de Graaf, Jacqueline, Loeffler, Markus, Kronenberg, Florian, Gu, Dongfeng, Erdmann, Jeanette, Schunkert, Heribert, Franks, Paul W, Linneberg, Allan, Jukema, J Wouter, Khera, Amit V, Männikkö, Minna, Jarvelin, Marjo-Riitta, Kutalik, Zoltan, Francesco, Cucca, Mook-Kanamori, Dennis O, van Dijk, Ko Willems, Watkins, Hugh, Strachan, David P, Grarup, Niels, Sever, Peter, Poulter, Neil, Chuang, Lee-Ming, Rotter, Jerome I, Dantoft, Thomas M, Karpe, Fredrik, Neville, Matt J, Timpson, Nicholas J, Cheng, Ching-Yu, Wong, Tien-Yin, Khor, Chiea Chuen, Li, Hengtong, Sabanayagam, Charumathi, Peters, Annette, Gieger, Christian, Hattersley, Andrew T, Pedersen, Nancy L, Magnusson, Patrik K E, Boomsma, Dorret I, Willemsen, Allegonda H M, Cupples, LAdrienne, van Meurs, Joyce B J, Ghanbari, Mohsen, Gordon-Larsen, Penny, Huang, Wei, Kim, Young Jin, Tabara, Yasuharu, Wareham, Nicholas J, Langenberg, Claudia, Zeggini, Eleftheria, Kuusisto, Johanna, Laakso, Markku, Ingelsson, Erik, Abecasis, Goncalo, Chambers, John C, Kooner, Jaspal S, de Vries, Paul S, Morrison, Alanna C, Hazelhurst, Scott, Ramsay, Michèle, North, Kari E, Daviglus, Martha, Kraft, Peter, Martin, Nicholas G, Whitfield, John B, Abbas, Shahid, Saleheen, Danish, Walters, Robin G, Holmes, Michael V, Black, Corri, Smith, Blair H, Baras, Aris, Justice, Anne E, Buring, Julie E, Ridker, Paul M, Chasman, Daniel I, Kooperberg, Charles, Tamiya, Gen, Yamamoto, Masayuki, van Heel, David A, Trembath, Richard C, Wei, Wei-Qi, Jarvik, Gail P, Namjou, Bahram, Hayes, M Geoffrey, Ritchie, Marylyn D, Jousilahti, Pekka, Salomaa, Veikko, Hveem, Kristian, Åsvold, Bjørn Olav, Kubo, Michiaki, Kamatani, Yoichiro, Okada, Yukinori, Murakami, Yoshinori, Kim, Bong-Jo, Thorsteinsdottir, Unnur, Stefansson, Kari, Zhang, Jifeng, Chen, YEugene, Ho, Yuk-Lam, Lynch, Julie A, Rader, Daniel J, Tsao, Philip S, Chang, Kyong-Mi, Cho, Kelly, O'Donnell, Christopher J, Gaziano, John M, Wilson, Peter W F, Frayling, Timothy M, Hirschhorn, Joel N, Kathiresan, Sekar, Mohlke, Karen L, Sun, Yan V, Morris, Andrew P, Boehnke, Michael, Brown, Christopher D, Natarajan, Pradeep, Deloukas, Panos, Willer, Cristen J, Assimes, Themistocles L, Peloso, Gina M, CDL Onderzoek Pasterkamp, Circulatory Health, Onderzoek Precision medicine, Zorgeenheid Vaatchirurgie Medisch, Infection & Immunity, Regenerative Medicine and Stem Cells, Team Medisch, Cardiovasculaire Epi Team 1, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Centraal Diagnostisch Laboratorium, Gezonde Vaten, Kanoni, Stavroula, Graham, Sarah E, Wang, Yuxuan, Surakka, Ida, Ramdas, Shweta, Zhu, Xiang, Clarke, Shoa L, Bhatti, Konain Fatima, Vedantam, Sailaja, Winkler, Thomas W, Locke, Adam E, Marouli, Eirini, Zajac, Greg J M, Wu, Kuan-Han H, Ntalla, Ioanna, Hui, Qin, Klarin, Derek, Hilliard, Austin T, Wang, Zeyuan, Xue, Chao, Thorleifsson, Gudmar, Helgadottir, Anna, Gudbjartsson, Daniel F, Holm, Hilma, Olafsson, Isleifur, Hwang, Mi Yeong, Han, Sohee, Akiyama, Masato, Sakaue, Saori, Terao, Chikashi, Kanai, Masahiro, Zhou, Wei, Brumpton, Ben M, Rasheed, Humaira, Havulinna, Aki S, Veturi, Yogasudha, Pacheco, Jennifer Allen, Rosenthal, Elisabeth A, Lingren, Todd, Feng, QiPing, Kullo, Iftikhar J, Narita, Akira, Takayama, Jun, Martin, Hilary C, Hunt, Karen A, Trivedi, Bhavi, Haessler, Jeffrey, Giulianini, Franco, Bradford, Yuki, Miller, Jason E, Campbell, Archie, Lin, Kuang, Millwood, Iona Y, Rasheed, Asif, Hindy, George, Faul, Jessica D, Zhao, Wei, Weir, David R, Turman, Constance, Huang, Hongyan, Graff, Mariaelisa, Choudhury, Ananyo, Sengupta, Dhriti, Mahajan, Anubha, Brown, Michael R, Zhang, Weihua, Yu, Ketian, Schmidt, Ellen M, Pandit, Anita, Gustafsson, Stefan, Yin, Xianyong, Luan, Jian'an, Zhao, Jing-Hua, Matsuda, Fumihiko, Jang, Hye-Mi, Yoon, Kyungheon, Medina-Gomez, Carolina, Pitsillides, Achilleas, Hottenga, Jouke Jan, Wood, Andrew R, Ji, Yingji, Gao, Zishan, Haworth, Simon, Yousri, Noha A, Mitchell, Ruth E, Chai, Jin Fang, Aadahl, Mette, Bjerregaard, Anne A, Yao, Jie, Manichaikul, Ani, Hwu, Chii-Min, Hung, Yi-Jen, Warren, Helen R, Ramirez, Julia, Bork-Jensen, Jette, Kårhus, Line L, Goel, Anuj, Sabater-Lleal, Maria, Noordam, Raymond, Mauro, Pala, Matteo, Floris, McDaid, Aaron F, Marques-Vidal, Pedro, Wielscher, Matthias, Trompet, Stella, Sattar, Naveed, Møllehave, Line T, Munz, Matthias, Zeng, Lingyao, Huang, Jianfeng, Yang, Bin, Poveda, Alaitz, Kurbasic, Azra, Lamina, Claudia, Forer, Lukas, Scholz, Markus, Galesloot, Tessel E, Bradfield, Jonathan P, Ruotsalainen, Sanni E, Daw, EWarwick, Zmuda, Joseph M, Mitchell, Jonathan S, Fuchsberger, Christian, Christensen, Henry, Brody, Jennifer A, Vazquez-Moreno, Miguel, Feitosa, Mary F, Wojczynski, Mary K, Wang, Zhe, Preuss, Michael H, Mangino, Massimo, Christofidou, Paraskevi, Verweij, Niek, Benjamins, Jan W, Engmann, Jorgen, Tsao, Noah L, Verma, Anurag, Slieker, Roderick C, Lo, Ken Sin, Zilhao, Nuno R, Le, Phuong, Kleber, Marcus E, Delgado, Graciela E, Huo, Shaofeng, Ikeda, Daisuke D, Iha, Hiroyuki, Yang, Jian, Liu, Jun, Demirkan, Ayşe, Leonard, Hampton L, Marten, Jonathan, Frank, Mirjam, Schmidt, Börge, Smyth, Laura J, Cañadas-Garre, Marisa, Wang, Chaolong, Nakatochi, Masahiro, Wong, Andrew, Hutri-Kähönen, Nina, Sim, Xueling, Xia, Rui, Huerta-Chagoya, Alicia, Fernandez-Lopez, Juan Carlos, Lyssenko, Valeriya, Nongmaithem, Suraj S, Bayyana, Swati, Stringham, Heather M, Irvin, Marguerite R, Oldmeadow, Christopher, Kim, Han-Na, Ryu, Seungho, Timmers, Paul R H J, Arbeeva, Liubov, Dorajoo, Rajkumar, Lange, Leslie A, Prasad, Gauri, Lorés-Motta, Laura, Pauper, Marc, Long, Jirong, Li, Xiaohui, Theusch, Elizabeth, Takeuchi, Fumihiko, Spracklen, Cassandra N, Loukola, Anu, Bollepalli, Sailalitha, Warner, Sophie C, Wang, Ya Xing, Wei, Wen B, Nutile, Teresa, Ruggiero, Daniela, Sung, Yun Ju, Chen, Shufeng, Liu, Fangchao, Yang, Jingyun, Kentistou, Katherine A, Banas, Bernhard, Nardone, Giuseppe Giovanni, Meidtner, Karina, Bielak, Lawrence F, Smith, Jennifer A, Hebbar, Prashantha, Farmaki, Aliki-Eleni, Hofer, Edith, Lin, Maoxuan, Concas, Maria Pina, Vaccargiu, Simona, van der Most, Peter J, Pitkänen, Niina, Cade, Brian E, van der Laan, Sander W, Chitrala, Kumaraswamy Naidu, Weiss, Stefan, Bentley, Amy R, Doumatey, Ayo P, Adeyemo, Adebowale A, Lee, Jong Young, Petersen, Eva R B, Nielsen, Aneta A, Choi, Hyeok Sun, Nethander, Maria, Freitag-Wolf, Sandra, Southam, Lorraine, Rayner, Nigel W, Wang, Carol A, Lin, Shih-Yi, Wang, Jun-Sing, Couture, Christian, Lyytikäinen, Leo-Pekka, Nikus, Kjell, Cuellar-Partida, Gabriel, Vestergaard, Henrik, Hidalgo, Bertha, Giannakopoulou, Olga, Cai, Qiuyin, Obura, Morgan O, van Setten, Jessica, Li, Xiaoyin, Liang, Jingjing, Tang, Hua, Terzikhan, Natalie, Shin, Jae Hun, Jackson, Rebecca D, Reiner, Alexander P, Martin, Lisa Warsinger, Chen, Zhengming, Li, Liming, Kawaguchi, Takahisa, Thiery, Joachim, Bis, Joshua C, Launer, Lenore J, Li, Huaixing, Nalls, Mike A, Raitakari, Olli T, Ichihara, Sahoko, Wild, Sarah H, Nelson, Christopher P, Campbell, Harry, Jäger, Susanne, Nabika, Toru, Al-Mulla, Fahd, Niinikoski, Harri, Braund, Peter S, Kolcic, Ivana, Kovacs, Peter, Giardoglou, Tota, Katsuya, Tomohiro, de Kleijn, Dominique, de Borst, Gert J, Kim, Eung Kweon, Adams, Hieab H H, Ikram, M Arfan, Zhu, Xiaofeng, Asselbergs, Folkert W, Kraaijeveld, Adriaan O, Beulens, Joline W J, Shu, Xiao-Ou, Rallidis, Loukianos S, Pedersen, Oluf, Hansen, Torben, Mitchell, Paul, Hewitt, Alex W, Kähönen, Mika, Pérusse, Louis, Bouchard, Claude, Tönjes, Anke, Chen, Yii-Der Ida, Pennell, Craig E, Mori, Trevor A, Lieb, Wolfgang, Franke, Andre, Ohlsson, Claes, Mellström, Dan, Cho, Yoon Shin, Lee, Hyejin, Yuan, Jian-Min, Koh, Woon-Puay, Rhee, Sang Youl, Woo, Jeong-Taek, Heid, Iris M, Stark, Klaus J, Zimmermann, Martina E, Völzke, Henry, Homuth, Georg, Evans, Michele K, Zonderman, Alan B, Polasek, Ozren, Pasterkamp, Gerard, Hoefer, Imo E, Redline, Susan, Pahkala, Katja, Oldehinkel, Albertine J, Snieder, Harold, Biino, Ginevra, Schmidt, Reinhold, Schmidt, Helena, Bandinelli, Stefania, Dedoussis, George, Thanaraj, Thangavel Alphonse, Kardia, Sharon L R, Peyser, Patricia A, Kato, Norihiro, Schulze, Matthias B, Girotto, Giorgia, Böger, Carsten A, Jung, Bettina, Joshi, Peter K, Bennett, David A, De Jager, Philip L, Lu, Xiangfeng, Mamakou, Vasiliki, Brown, Morris, Caulfield, Mark J, Munroe, Patricia B, Guo, Xiuqing, Ciullo, Marina, Jonas, Jost B, Samani, Nilesh J, Kaprio, Jaakko, Pajukanta, Päivi, Tusié-Luna, Teresa, Aguilar-Salinas, Carlos A, Adair, Linda S, Bechayda, Sonny Augustin, de Silva, H Janaka, Wickremasinghe, Ananda R, Krauss, Ronald M, Wu, Jer-Yuarn, Zheng, Wei, Hollander, Anneke Iden, Bharadwaj, Dwaipayan, Correa, Adolfo, Wilson, James G, Lind, Lars, Heng, Chew-Kiat, Nelson, Amanda E, Golightly, Yvonne M, Wilson, James F, Penninx, Brenda, Kim, Hyung-Lae, Attia, John, Scott, Rodney J, Rao, D C, Arnett, Donna K, Hunt, Steven C, Walker, Mark, Koistinen, Heikki A, Chandak, Giriraj R, Mercader, Josep M, Costanzo, Maria C, Jang, Dongkeun, Burtt, Noël P, Villalpando, Clicerio Gonzalez, Orozco, Lorena, Fornage, Myriam, Tai, EShyong, van Dam, Rob M, Lehtimäki, Terho, Chaturvedi, Nish, Yokota, Mitsuhiro, Liu, Jianjun, Reilly, Dermot F, McKnight, Amy Jayne, Kee, Frank, Jöckel, Karl-Heinz, McCarthy, Mark I, Palmer, Colin N A, Vitart, Veronique, Hayward, Caroline, Simonsick, Eleanor, van Duijn, Cornelia M, Jin, Zi-Bing, Qu, Jia, Hishigaki, Haretsugu, Lin, Xu, März, Winfried, Gudnason, Vilmundur, Tardif, Jean-Claude, Lettre, Guillaume, Hart, Leen M 't, Elders, Petra J M, Damrauer, Scott M, Kumari, Meena, Kivimaki, Mika, van der Harst, Pim, Spector, Tim D, Loos, Ruth J F, Province, Michael A, Parra, Esteban J, Cruz, Miguel, Psaty, Bruce M, Brandslund, Ivan, Pramstaller, Peter P, Rotimi, Charles N, Christensen, Kaare, Ripatti, Samuli, Widén, Elisabeth, Hakonarson, Hakon, Grant, Struan F A, Kiemeney, Lambertus A L M, de Graaf, Jacqueline, Loeffler, Markus, Kronenberg, Florian, Gu, Dongfeng, Erdmann, Jeanette, Schunkert, Heribert, Franks, Paul W, Linneberg, Allan, Jukema, J Wouter, Khera, Amit V, Männikkö, Minna, Jarvelin, Marjo-Riitta, Kutalik, Zoltan, Francesco, Cucca, Mook-Kanamori, Dennis O, van Dijk, Ko Willems, Watkins, Hugh, Strachan, David P, Grarup, Niels, Sever, Peter, Poulter, Neil, Chuang, Lee-Ming, Rotter, Jerome I, Dantoft, Thomas M, Karpe, Fredrik, Neville, Matt J, Timpson, Nicholas J, Cheng, Ching-Yu, Wong, Tien-Yin, Khor, Chiea Chuen, Li, Hengtong, Sabanayagam, Charumathi, Peters, Annette, Gieger, Christian, Hattersley, Andrew T, Pedersen, Nancy L, Magnusson, Patrik K E, Boomsma, Dorret I, Willemsen, Allegonda H M, Cupples, LAdrienne, van Meurs, Joyce B J, Ghanbari, Mohsen, Gordon-Larsen, Penny, Huang, Wei, Kim, Young Jin, Tabara, Yasuharu, Wareham, Nicholas J, Langenberg, Claudia, Zeggini, Eleftheria, Kuusisto, Johanna, Laakso, Markku, Ingelsson, Erik, Abecasis, Goncalo, Chambers, John C, Kooner, Jaspal S, de Vries, Paul S, Morrison, Alanna C, Hazelhurst, Scott, Ramsay, Michèle, North, Kari E, Daviglus, Martha, Kraft, Peter, Martin, Nicholas G, Whitfield, John B, Abbas, Shahid, Saleheen, Danish, Walters, Robin G, Holmes, Michael V, Black, Corri, Smith, Blair H, Baras, Aris, Justice, Anne E, Buring, Julie E, Ridker, Paul M, Chasman, Daniel I, Kooperberg, Charles, Tamiya, Gen, Yamamoto, Masayuki, van Heel, David A, Trembath, Richard C, Wei, Wei-Qi, Jarvik, Gail P, Namjou, Bahram, Hayes, M Geoffrey, Ritchie, Marylyn D, Jousilahti, Pekka, Salomaa, Veikko, Hveem, Kristian, Åsvold, Bjørn Olav, Kubo, Michiaki, Kamatani, Yoichiro, Okada, Yukinori, Murakami, Yoshinori, Kim, Bong-Jo, Thorsteinsdottir, Unnur, Stefansson, Kari, Zhang, Jifeng, Chen, YEugene, Ho, Yuk-Lam, Lynch, Julie A, Rader, Daniel J, Tsao, Philip S, Chang, Kyong-Mi, Cho, Kelly, O'Donnell, Christopher J, Gaziano, John M, Wilson, Peter W F, Frayling, Timothy M, Hirschhorn, Joel N, Kathiresan, Sekar, Mohlke, Karen L, Sun, Yan V, Morris, Andrew P, Boehnke, Michael, Brown, Christopher D, Natarajan, Pradeep, Deloukas, Panos, Willer, Cristen J, Assimes, Themistocles L, and Peloso, Gina M
- Published
- 2022
45. Abstract 14753: Loss of Function ABCC8 Mutations Are Associated With Pulmonary Arterial Hypertension
- Author
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Bohnen, Michael S, Ma, Lijiang, Zhu, Na, Qi, Hongjian, McClenaghan, Conor, Gonzaga-Jauregui, Claudia, Dewey, Frederick E, Overton, John D, Reid, Jeffrey G, Shuldiner, Alan R, Baras, Aris, Sampson, Kevin J, Bleda, Marta, Hadinnapola, Charaka, Haimel, Matthias, Bogaard, Harm J, Church, Colin, Coghlan, Gerry, Corris, Paul A, Eyries, Mélanie, Gibbs, J. Simon R, Girerd, Barbara, Houweling, Arjan C, Humbert, Marc, Kiely, David G, Lawrie, Allan, MacKenzie Ross, Rob V, Martin, Jennifer M, Montani, David, Peacock, Andrew J, Pepke-Zaba, Joanna, Soubrier, Florent, Suntharalingam, Jay, Toshner, Mark, Treacy, Carmen M, Trembath, Richard C, Vonk Noordegraaf, Anton, Wharton, John, Wilkins, Martin R, Wort, Stephen J, Yates, Katherine, Gräf, Stefan, Morrell, Nicholas W, Krishnan, Usha, Rosenzweig, Erika B, Shen, Yufeng, Nichols, Colin G, Kass, Robert S, and Chung, Wendy K
- Published
- 2017
46. Exome-wide association study reveals novel psoriasis susceptibility locus at TNFSF15 and rare protective alleles in genes contributing to type I IFN signalling
- Author
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Dand, Nick, Mucha, Sören, Tsoi, Lam C, Mahil, Satveer K, Stuart, Philip E, Arnold, Andreas, Baurecht, Hansjörg, Burden, A David, Callis Duffin, Kristina, Chandran, Vinod, Curtis, Charles J, Das, Sayantan, Ellinghaus, David, Ellinghaus, Eva, Enerback, Charlotta, Esko, Tõnu, Gladman, Dafna D, Griffiths, Christopher E M, Gudjonsson, Johann E, Hoffman, Per, Homuth, Georg, Hüffmeier, Ulrike, Krueger, Gerald G, Laudes, Matthias, Lee, Sang Hyuck, Lieb, Wolfgang, Lim, Henry W, Löhr, Sabine, Mrowietz, Ulrich, Müller-Nurayid, Martina, Nöthen, Markus, Peters, Annette, Rahman, Proton, Reis, André, Reynolds, Nick J, Rodriguez, Elke, Schmidt, Carsten O, Spain, Sarah L, Strauch, Konstantin, Tejasvi, Trilokraj, Voorhees, John J, Warren, Richard B, Weichenthal, Michael, Weidinger, Stephan, Zawistowski, Matthew, Nair, Rajan P, Capon, Francesca, Smith, Catherine H, Trembath, Richard C, Abecasis, Goncalo R, Elder, James T, Franke, Andre, Simpson, Michael A, and Barker, Jonathan N
- Published
- 2017
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47. ARHGAP31, DOCK6, RBPJ, EOGT, and Adams-Oliver Syndrome
- Author
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Southgate, Laura, primary and Trembath, Richard C., additional
- Published
- 2016
- Full Text
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48. Mendelian randomisation and experimental medicine approaches to IL-6 as a drug target in PAH
- Author
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Toshner, Mark, Church, Colin, Harbaum, Lars, Rhodes, Christopher, Villar Moreschi, Sofia S, Liley, James, Jones, Rowena, Arora, Amit, Batai, Ken, Desai, Ankit A, Coghlan, John G, Gibbs, J Simon R, Gor, Dee, Gräf, Stefan, Harlow, Louise, Hernandez-Sanchez, Jules, Howard, Luke S, Humbert, Marc, Karnes, Jason, Kiely, David G, Kittles, Rick, Knightbridge, Emily, Lam, Brian, Lutz, Katie A, Nichols, William C, Pauciulo, Michael W, Pepke-Zaba, Joanna, Suntharalingam, Jay, Soubrier, Florent, Trembath, Richard C, Schwantes-An, Tae-Hwi L, Wort, S John, Wilkins, Martin, Gaine, Sean, Morrell, Nicholas W, Corris, Paul A, Toshner, Mark [0000-0002-3969-6143], Villar, Sofia [0000-0001-7755-2637], Jones, Rowena [0000-0002-4551-2320], Graf, Stefan [0000-0002-1315-8873], Lam, Brian [0000-0002-3638-9025], Morrell, Nicholas [0000-0001-5700-9792], Apollo - University of Cambridge Repository, and British Heart Foundation
- Subjects
Adult ,Male ,Pulmonary Arterial Hypertension ,Biomedical Research ,Interleukin-6 ,Respiratory System ,Uniphy Clinical Trials Network ,Middle Aged ,Treatment Outcome ,Humans ,Familial Primary Pulmonary Hypertension ,Female ,11 Medical and Health Sciences ,Aged - Abstract
Inflammation and dysregulated immunity are important in the development of pulmonary arterial hypertension. Compelling preclinical data supports the therapeutic blockade of interleukin-6 signalling.We conducted an open-label phase-II study of intravenous tocilizumab (8 mg·kg-1) over 6 months in group 1 pulmonary arterial hypertension. Co-primary endpoints were safety, defined by incidence and severity of adverse events, and change in pulmonary vascular resistance. Separately, a Mendelian randomisation study was undertaken on 11,744 individuals with European ancestry including 2085 patients with idiopathic/heritable disease for the IL6R variant (rs7529229), known to associate with circulating IL6R levels.Twenty-nine patients (M/F 10/19; mean age 54.9[SD11.4]) were recruited. Nineteen had heritable/idiopathic and ten connective tissue disease associated pulmonary arterial hypertension. Six were withdrawn prior to drug administration. Twenty-three patients received at least one dose of tocilizumab. Tocilizumab was discontinued in 4 patients due to serious adverse events. There were no deaths. Despite evidence of target engagement in plasma interleukin-6 and C-reactive protein levels, both intention-to-treat and modified intention-to-treat analyses demonstrated no change in pulmonary vascular resistance. Inflammatory markers did not predict treatment response. Mendelian randomisation did not support an effect of the lead IL6R variant on risk of pulmonary arterial hypertension (OR 0.99, p=0.88).Adverse events were consistent with the known safety profile of tocilizumab. Tocilizumab did not show any consistent treatment effect.
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- 2022
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49. Mutations in the Pericentrin (PCNT) Gene Cause Primordial Dwarfism
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Rauch, Anita, Thiel, Christian T., Schindler, Detlev, Wick, Ursula, Crow, Yanick J., Ekici, Arif B., van Essen, Anthonie J., Goecke, Timm O., Al-Gazali, Lihadh, Chrzanowska, Krystyna H., Zweier, Christiane, Brunner, Han G., Becker, Kristin, Curry, Cynthia J., Dallapiccola, Bruno, Devriendt, Koenraad, Dörfler, Arnd, Kinning, Esther, Megarbane, André, Meinecke, Peter, Semple, Robert K., Spranger, Stephanie, Toutain, Annick, Trembath, Richard C., Voss, Egbert, Wilson, Louise, Hennekam, Raoul, de Zegher, Francis, Dörr, Helmuth-Günther, and Reis, André
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- 2008
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50. Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders
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Blokland, Gabriëlla A.M., primary, Grove, Jakob, additional, Chen, Chia-Yen, additional, Cotsapas, Chris, additional, Tobet, Stuart, additional, Handa, Robert, additional, St Clair, David, additional, Lencz, Todd, additional, Mowry, Bryan J., additional, Periyasamy, Sathish, additional, Cairns, Murray J., additional, Tooney, Paul A., additional, Wu, Jing Qin, additional, Kelly, Brian, additional, Kirov, George, additional, Sullivan, Patrick F., additional, Corvin, Aiden, additional, Riley, Brien P., additional, Esko, Tõnu, additional, Milani, Lili, additional, Jönsson, Erik G., additional, Palotie, Aarno, additional, Ehrenreich, Hannelore, additional, Begemann, Martin, additional, Steixner-Kumar, Agnes, additional, Sham, Pak C., additional, Iwata, Nakao, additional, Weinberger, Daniel R., additional, Gejman, Pablo V., additional, Sanders, Alan R., additional, Buxbaum, Joseph D., additional, Rujescu, Dan, additional, Giegling, Ina, additional, Konte, Bettina, additional, Hartmann, Annette M., additional, Bramon, Elvira, additional, Murray, Robin M., additional, Pato, Michele T., additional, Lee, Jimmy, additional, Melle, Ingrid, additional, Molden, Espen, additional, Ophoff, Roel A., additional, McQuillin, Andrew, additional, Bass, Nicholas J., additional, Adolfsson, Rolf, additional, Malhotra, Anil K., additional, Martin, Nicholas G., additional, Fullerton, Janice M., additional, Mitchell, Philip B., additional, Schofield, Peter R., additional, Forstner, Andreas J., additional, Degenhardt, Franziska, additional, Schaupp, Sabrina, additional, Comes, Ashley L., additional, Kogevinas, Manolis, additional, Guzman-Parra, José, additional, Reif, Andreas, additional, Streit, Fabian, additional, Sirignano, Lea, additional, Cichon, Sven, additional, Grigoroiu-Serbanescu, Maria, additional, Hauser, Joanna, additional, Lissowska, Jolanta, additional, Mayoral, Fermin, additional, Müller-Myhsok, Bertram, additional, Świątkowska, Beata, additional, Schulze, Thomas G., additional, Nöthen, Markus M., additional, Rietschel, Marcella, additional, Kelsoe, John, additional, Leboyer, Marion, additional, Jamain, Stéphane, additional, Etain, Bruno, additional, Bellivier, Frank, additional, Vincent, John B., additional, Alda, Martin, additional, O’Donovan, Claire, additional, Cervantes, Pablo, additional, Biernacka, Joanna M., additional, Frye, Mark, additional, McElroy, Susan L., additional, Scott, Laura J., additional, Stahl, Eli A., additional, Landén, Mikael, additional, Hamshere, Marian L., additional, Smeland, Olav B., additional, Djurovic, Srdjan, additional, Vaaler, Arne E., additional, Andreassen, Ole A., additional, Baune, Bernhard T., additional, Air, Tracy, additional, Preisig, Martin, additional, Uher, Rudolf, additional, Levinson, Douglas F., additional, Weissman, Myrna M., additional, Potash, James B., additional, Shi, Jianxin, additional, Knowles, James A., additional, Perlis, Roy H., additional, Lucae, Susanne, additional, Boomsma, Dorret I., additional, Penninx, Brenda W.J.H., additional, Hottenga, Jouke-Jan, additional, de Geus, Eco J.C., additional, Willemsen, Gonneke, additional, Milaneschi, Yuri, additional, Tiemeier, Henning, additional, Grabe, Hans J., additional, Teumer, Alexander, additional, Van der Auwera, Sandra, additional, Völker, Uwe, additional, Hamilton, Steven P., additional, Magnusson, Patrik K.E., additional, Viktorin, Alexander, additional, Mehta, Divya, additional, Mullins, Niamh, additional, Adams, Mark J., additional, Breen, Gerome, additional, McIntosh, Andrew M., additional, Lewis, Cathryn M., additional, Hougaard, David M., additional, Nordentoft, Merete, additional, Mors, Ole, additional, Mortensen, Preben B., additional, Werge, Thomas, additional, Als, Thomas D., additional, Børglum, Anders D., additional, Petryshen, Tracey L., additional, Smoller, Jordan W., additional, Goldstein, Jill M., additional, Ripke, Stephan, additional, Neale, Benjamin M., additional, Walters, James T.R., additional, Farh, Kai-How, additional, Holmans, Peter A., additional, Lee, Phil, additional, Bulik-Sullivan, Brendan, additional, Collier, David A., additional, Huang, Hailiang, additional, Pers, Tune H., additional, Agartz, Ingrid, additional, Agerbo, Esben, additional, Albus, Margot, additional, Alexander, Madeline, additional, Amin, Farooq, additional, Bacanu, Silviu A., additional, Belliveau, Richard A., additional, Bene, Judit, additional, Bergen, Sarah E., additional, Bevilacqua, Elizabeth, additional, Bigdeli, Tim B., additional, Black, Donald W., additional, Bruggeman, Richard, additional, Buccola, Nancy G., additional, Buckner, Randy L., additional, Byerley, William, additional, Cahn, Wiepke, additional, Cai, Guiqing, additional, Campion, Dominique, additional, Cantor, Rita M., additional, Carr, Vaughan J., additional, Carrera, Noa, additional, Catts, Stanley V., additional, Chambert, Kimberly D., additional, Chan, Raymond C.K., additional, Chen, Ronald Y.L., additional, Chen, Eric Y.H., additional, Cheng, Wei, additional, Cheung, Eric F.C., additional, Chong, Siow Ann, additional, Cloninger, C. Robert, additional, Cohen, David, additional, Cohen, Nadine, additional, Cormican, Paul, additional, Craddock, Nick, additional, Crowley, James J., additional, Curtis, David, additional, Davidson, Michael, additional, Davis, Kenneth L., additional, Del Favero, Jurgen, additional, Demontis, Ditte, additional, Dikeos, Dimitris, additional, Dinan, Timothy, additional, Donohoe, Gary, additional, Drapeau, Elodie, additional, Duan, Jubao, additional, Dudbridge, Frank, additional, Durmishi, Naser, additional, Eichhammer, Peter, additional, Eriksson, Johan, additional, Escott-Price, Valentina, additional, Essioux, Laurent, additional, Fanous, Ayman H., additional, Farrell, Martilias S., additional, Frank, Josef, additional, Franke, Lude, additional, Freedman, Robert, additional, Freimer, Nelson B., additional, Friedl, Marion, additional, Friedman, Joseph I., additional, Fromer, Menachem, additional, Genovese, Giulio, additional, Georgieva, Lyudmila, additional, Giusti-Rodríguez, Paola, additional, Godard, Stephanie, additional, Goldstein, Jacqueline I., additional, Golimbet, Vera, additional, Gopal, Srihari, additional, Gratten, Jacob, additional, de Haan, Lieuwe, additional, Hammer, Christian, additional, Hansen, Mark, additional, Hansen, Thomas, additional, Haroutunian, Vahram, additional, Henskens, Frans A., additional, Herms, Stefan, additional, Hirschhorn, Joel N., additional, Hoffmann, Per, additional, Hofman, Andrea, additional, Hollegaard, Mads V., additional, Ikeda, Masashi, additional, Joa, Inge, additional, Julià, Antonio, additional, Kahn, René S., additional, Kalaydjieva, Luba, additional, Karachanak-Yankova, Sena, additional, Karjalainen, Juha, additional, Kavanagh, David, additional, Keller, Matthew C., additional, Kennedy, James L., additional, Khrunin, Andrey, additional, Kim, Yunjung, additional, Klovins, Janis, additional, Kucinskas, Vaidutis, additional, Kucinskiene, Zita Ausrele, additional, Kuzelova-Ptackova, Hana, additional, Kähler, Anna K., additional, Laurent, Claudine, additional, Lee Chee Keong, Jimmy, additional, Lee, S. Hong, additional, Legge, Sophie E., additional, Lerer, Bernard, additional, Li, Miaoxin, additional, Li, Tao, additional, Liang, Kung-Yee, additional, Lieberman, Jeffrey, additional, Limborska, Svetlana, additional, Loughland, Carmel M., additional, Lubinski, Jan, additional, Lönnqvist, Jouko, additional, Macek, Milan, additional, Maher, Brion S., additional, Maier, Wolfgang, additional, Mallet, Jacques, additional, Marsal, Sara, additional, Mattheisen, Manuel, additional, Mattingsdal, Morten, additional, McCarley, Robert W., additional, McDonald, Colm, additional, Meier, Sandra, additional, Meijer, Carin J., additional, Melegh, Bela, additional, Mesholam-Gately, Raquelle I., additional, Metspalu, Andres, additional, Michie, Patricia T., additional, Milanova, Vihra, additional, Mokrab, Younes, additional, Morris, Derek W., additional, Murphy, Kieran C., additional, Myin-Germeys, Inez, additional, Nelis, Mari, additional, Nenadic, Igor, additional, Nertney, Deborah A., additional, Nestadt, Gerald, additional, Nicodemus, Kristin K., additional, Nikitina-Zake, Liene, additional, Nisenbaum, Laura, additional, Nordin, Annelie, additional, O’Callaghan, Eadbhard, additional, O’Dushlaine, Colm, additional, O’Neill, F. Anthony, additional, Oh, Sang-Yun, additional, Olincy, Ann, additional, Olsen, Line, additional, Van Os, Jim, additional, Pantelis, Christos, additional, Papadimitriou, George N., additional, Papiol, Sergi, additional, Parkhomenko, Elena, additional, Paunio, Tiina, additional, Pejovic-Milovancevic, Milica, additional, Perkins, Diana O., additional, Pietiläinen, Olli, additional, Pimm, Jonathan, additional, Pocklington, Andrew J., additional, Powell, John, additional, Price, Alkes, additional, Pulver, Ann E., additional, Purcell, Shaun M., additional, Quested, Digby, additional, Rasmussen, Henrik B., additional, Reichenberg, Abraham, additional, Reimers, Mark A., additional, Richards, Alexander L., additional, Roffman, Joshua L., additional, Roussos, Panos, additional, Ruderfer, Douglas M., additional, Salomaa, Veikko, additional, Schall, Ulrich, additional, Schubert, Christian R., additional, Schwab, Sibylle G., additional, Scolnick, Edward M., additional, Scott, Rodney J., additional, Seidman, Larry J., additional, Sigurdsson, Engilbert, additional, Silagadze, Teimuraz, additional, Silverman, Jeremy M., additional, Sim, Kang, additional, Slominsky, Petr, additional, So, Hon-Cheong, additional, Spencer, Chris C.A., additional, Stefansson, Hreinn, additional, Steinberg, Stacy, additional, Stogmann, Elisabeth, additional, Straub, Richard E., additional, Strengman, Eric, additional, Strohmaier, Jana, additional, Stroup, T. Scott, additional, Subramaniam, Mythily, additional, Suvisaari, Jaana, additional, Svrakic, Dragan M., additional, Szatkiewicz, Jin P., additional, Söderman, Erik, additional, Thirumalai, Srinivas, additional, Toncheva, Draga, additional, Tosato, Sarah, additional, Veijola, Juha, additional, Waddington, John, additional, Walsh, Dermot, additional, Wang, Dai, additional, Wang, Qiang, additional, Webb, Bradley T., additional, Weiser, Mark, additional, Wildenauer, Dieter B., additional, Williams, Nigel M., additional, Williams, Stephanie, additional, Witt, Stephanie H., additional, Wolen, Aaron R., additional, Wong, Emily H.M., additional, Wormley, Brandon K., additional, Xi, Hualin Simon, additional, Zai, Clement C., additional, Zheng, Xuebin, additional, Zimprich, Fritz, additional, Wray, Naomi R., additional, Stefansson, Kari, additional, Visscher, Peter M., additional, Blackwood, Douglas H.R., additional, Darvasi, Ariel, additional, Domenici, Enrico, additional, Gill, Michael, additional, Gurling, Hugh, additional, Hultman, Christina M., additional, Jablensky, Assen V., additional, Kendler, Kenneth S., additional, Knight, Jo, additional, Li, Qingqin S., additional, Liu, Jianjun, additional, McCarroll, Steven A., additional, Moran, Jennifer L., additional, Owen, Michael J., additional, Pato, Carlos N., additional, Posthuma, Danielle, additional, Sklar, Pamela, additional, Wendland, Jens R., additional, Daly, Mark J., additional, O’Donovan, Michael C., additional, Donnelly, Peter, additional, Barroso, Ines, additional, Blackwell, Jenefer M., additional, Brown, Matthew A., additional, Casas, Juan P., additional, Deloukas, Panos, additional, Duncanson, Audrey, additional, Jankowski, Janusz, additional, Markus, Hugh S., additional, Mathew, Christopher G., additional, Palmer, Colin N.A., additional, Plomin, Robert, additional, Rautanen, Anna, additional, Sawcer, Stephen J., additional, Trembath, Richard C., additional, Viswanathan, Ananth C., additional, Wood, Nicholas W., additional, Band, Gavin, additional, Bellenguez, Céline, additional, Freeman, Colin, additional, Giannoulatou, Eleni, additional, Hellenthal, Garrett, additional, Pearson, Richard, additional, Pirinen, Matti, additional, Strange, Amy, additional, Su, Zhan, additional, Vukcevic, Damjan, additional, Langford, Cordelia, additional, Blackburn, Hannah, additional, Bumpstead, Suzannah J., additional, Dronov, Serge, additional, Edkins, Sarah, additional, Gillman, Matthew, additional, Gray, Emma, additional, Gwilliam, Rhian, additional, Hammond, Naomi, additional, Hunt, Sarah E., additional, Jayakumar, Alagurevathi, additional, Liddle, Jennifer, additional, McCann, Owen T., additional, Potter, Simon C., additional, Ravindrarajah, Radhi, additional, Ricketts, Michelle, additional, Tashakkori-Ghanbaria, Avazeh, additional, Waller, Matthew, additional, Weston, Paul, additional, Whittaker, Pamela, additional, Widaa, Sara, additional, McCarthy, Mark I., additional, Arranz, Maria J., additional, Bakker, Steven, additional, Bender, Stephan, additional, Crespo-Facorro, Benedicto, additional, Hall, Jeremy, additional, Iyegbe, Conrad, additional, Lawrie, Stephen, additional, Lin, Kuang, additional, Linszen, Don H., additional, Mata, Ignacio, additional, Walshe, Muriel, additional, Weisbrod, Matthias, additional, Wiersma, Durk, additional, Trubetskoy, Vassily, additional, Wang, Yunpeng, additional, Coleman, Jonathan R.I., additional, Gaspar, Héléna A., additional, de Leeuw, Christiaan A., additional, Whitehead Pavlides, Jennifer M., additional, Trzaskowski, Maciej, additional, Byrne, Enda M., additional, Abbott, Liam, additional, Akil, Huda, additional, Albani, Diego, additional, Alliey-Rodriguez, Ney, additional, Anjorin, Adebayo, additional, Antilla, Verneri, additional, Awasthi, Swapnil, additional, Badner, Judith A., additional, Bækvad-Hansen, Marie, additional, Barchas, Jack D., additional, Bass, Nicholas, additional, Bauer, Michael, additional, Belliveau, Richard, additional, Pedersen, Carsten Bøcker, additional, Bøen, Erlend, additional, Boks, Marco P., additional, Boocock, James, additional, Budde, Monika, additional, Bunney, William, additional, Burmeister, Margit, additional, Bybjerg-Grauholm, Jonas, additional, Casas, Miquel, additional, Cerrato, Felecia, additional, Chambert, Kimberly, additional, Charney, Alexander W., additional, Chen, Danfeng, additional, Churchhouse, Claire, additional, Clarke, Toni-Kim, additional, Coryell, William, additional, Craig, David W., additional, Cruceanu, Cristiana, additional, Czerski, Piotr M., additional, Dale, Anders M., additional, de Jong, Simone, additional, Del-Favero, Jurgen, additional, DePaulo, J. Raymond, additional, Dobbyn, Amanda L., additional, Dumont, Ashley, additional, Elvsåshagen, Torbjørn, additional, Fan, Chun Chieh, additional, Fischer, Sascha B., additional, Flickinger, Matthew, additional, Foroud, Tatiana M., additional, Forty, Liz, additional, Fraser, Christine, additional, Gade, Katrin, additional, Gage, Diane, additional, Garnham, Julie, additional, Giambartolomei, Claudia, additional, Pedersen, Marianne Giørtz, additional, Goldstein, Jaqueline, additional, Gordon, Scott D., additional, Gordon-Smith, Katherine, additional, Green, Elaine K., additional, Green, Melissa J., additional, Greenwood, Tiffany A., additional, Guan, Weihua, additional, Hautzinger, Martin, additional, Heilbronner, Urs, additional, Hipolito, Maria, additional, Holland, Dominic, additional, Huckins, Laura, additional, Johnson, Jessica S., additional, Kandaswamy, Radhika, additional, Karlsson, Robert, additional, Kittel-Schneider, Sarah, additional, Koller, Anna C., additional, Kupka, Ralph, additional, Lavebratt, Catharina, additional, Lawrence, Jacob, additional, Lawson, William B., additional, Leber, Markus, additional, Lee, Phil H., additional, Levy, Shawn E., additional, Li, Jun Z., additional, Liu, Chunyu, additional, Maaser, Anna, additional, MacIntyre, Donald J., additional, Mahon, Pamela B., additional, Martinsson, Lina, additional, McCarroll, Steve, additional, McGuffin, Peter, additional, McInnis, Melvin G., additional, McKay, James D., additional, Medeiros, Helena, additional, Medland, Sarah E., additional, Meng, Fan, additional, Montgomery, Grant W., additional, Mühleisen, Thomas W., additional, Nguyen, Hoang, additional, Nievergelt, Caroline M., additional, Adolfsson, Annelie Nordin, additional, Nwulia, Evaristus A., additional, O'Donovan, Claire, additional, Olde Loohuis, Loes M., additional, Ori, Anil P.S., additional, Oruc, Lilijana, additional, Ösby, Urban, additional, Perry, Amy, additional, Pfennig, Andrea, additional, Regeer, Eline J., additional, Reinbold, Céline S., additional, Rice, John P., additional, Rivas, Fabio, additional, Rivera, Margarita, additional, Ryu, Euijung, additional, Sánchez-Mora, Cristina, additional, Schatzberg, Alan F., additional, Scheftner, William A., additional, Schork, Nicholas J., additional, Weickert, Cynthia Shannon, additional, Shehktman, Tatyana, additional, Shilling, Paul D., additional, Slaney, Claire, additional, Sobell, Janet L., additional, Hansen, Christine Søholm, additional, Spijker, Anne T., additional, Steffens, Michael, additional, Strauss, John S., additional, Szelinger, Szabolcs, additional, Thompson, Robert C., additional, Thorgeirsson, Thorgeir E., additional, Treutlein, Jens, additional, Vedder, Helmut, additional, Wang, Weiqing, additional, Watson, Stanley J., additional, Weickert, Thomas W., additional, Xi, Simon, additional, Xu, Wei, additional, Young, Allan H., additional, Zandi, Peter, additional, Zhang, Peng, additional, Zöllner, Sebastian, additional, Abdellaoui, Abdel, additional, Air, Tracy M., additional, Andlauer, Till F.M., additional, Bacanu, Silviu-Alin, additional, Beekman, Aartjan T.F., additional, Binder, Elisabeth B., additional, Bryois, Julien, additional, Buttenschøn, Henriette N., additional, Cai, Na, additional, Castelao, Enrique, additional, Christensen, Jane Hvarregaard, additional, Colodro-Conde, Lucía, additional, Couvy-Duchesne, Baptiste, additional, Crawford, Gregory E., additional, Davies, Gail, additional, Deary, Ian J., additional, Derks, Eske M., additional, Direk, Nese, additional, Dolan, Conor V., additional, Dunn, Erin C., additional, Eley, Thalia C., additional, Hassan Kiadeh, Farnush Farhadi, additional, Finucane, Hilary K., additional, Foo, Jerome C., additional, Goes, Fernando S., additional, Hall, Lynsey S., additional, Hansen, Thomas F., additional, Hickie, Ian B., additional, Homuth, Georg, additional, Horn, Carsten, additional, Howard, David M., additional, Ising, Marcus, additional, Jansen, Rick, additional, Jones, Ian, additional, Jones, Lisa A., additional, Jorgenson, Eric, additional, Kohane, Isaac S., additional, Kraft, Julia, additional, Kretzschmar, Warren W., additional, Kutalik, Zoltán, additional, Li, Yihan, additional, Lind, Penelope A., additional, MacKinnon, Dean F., additional, Maier, Robert M., additional, Marchini, Jonathan, additional, Mbarek, Hamdi, additional, McGrath, Patrick, additional, Middeldorp, Christel M., additional, Mihailov, Evelin, additional, Mondimore, Francis M., additional, Mostafavi, Sara, additional, Nauck, Matthias, additional, Ng, Bernard, additional, Nivard, Michel G., additional, Nyholt, Dale R., additional, O'Reilly, Paul F., additional, Oskarsson, Hogni, additional, Painter, Jodie N., additional, Peterson, Roseann E., additional, Peyrot, Wouter J., additional, Pistis, Giorgio, additional, Quiroz, Jorge A., additional, Qvist, Per, additional, Mirza, Saira Saeed, additional, Schoevers, Robert, additional, Schulte, Eva C., additional, Shen, Ling, additional, Shyn, Stanley I., additional, Sinnamon, Grant C.B., additional, Smit, Johannes H., additional, Smith, Daniel J., additional, Tansey, Katherine E., additional, Teismann, Henning, additional, Thompson, Wesley, additional, Thomson, Pippa A., additional, Traylor, Matthew, additional, Uitterlinden, André G., additional, Umbricht, Daniel, additional, van Hemert, Albert M., additional, Weinsheimer, Shantel Marie, additional, Wellmann, Jürgen, additional, Wu, Yang, additional, Xi, Hualin S., additional, Yang, Jian, additional, Zhang, Futao, additional, Arolt, Volker, additional, Berger, Klaus, additional, Dannlowski, Udo, additional, Domschke, Katharina, additional, Hayward, Caroline, additional, Heath, Andrew C., additional, Kloiber, Stefan, additional, Lewis, Glyn, additional, Madden, Pamela AF., additional, Magnusson, Patrik K., additional, Mortensen, Preben Bo, additional, O'Donovan, Michael C., additional, Paciga, Sara A., additional, Pedersen, Nancy L., additional, Porteous, David J., additional, Schaefer, Catherine, additional, Völzke, Henry, additional, Blokland, Gabriëlla A.M., additional, Bortolato, Marco, additional, Bralten, Janita, additional, Bulik, Cynthia M., additional, Burton, Christie L., additional, Carey, Caitlin E., additional, Davis, Lea K., additional, Duncan, Laramie E., additional, Edenberg, Howard J., additional, Erdman, Lauren, additional, Faraone, Stephen V., additional, Goleva, Slavina B., additional, Guo, Wei, additional, Hübel, Christopher, additional, Huckins, Laura M., additional, Khramtsova, Ekaterina A., additional, Martin, Joanna, additional, Mathews, Carol A., additional, Robinson, Elise, additional, Stahl, Eli, additional, Stranger, Barbara E., additional, Traglia, Michela, additional, Walters, Raymond K., additional, Weiss, Lauren A., additional, Winham, Stacey J., additional, Yao, Yin, additional, Skajaa, Kristjar, additional, Nöthen, Markus, additional, Owen, Michael, additional, Yolken, Robert H., additional, Plath, Niels, additional, Mill, Jonathan, additional, and Geschwind, Daniel, additional
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- 2022
- Full Text
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