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23 results on '"Travers, Meghan"'

1. REPLY TO HAFFNER ET AL. : DNA hypomethylation renders tumors more immunogenic

Author

Stone, Meredith L., Chiappinelli, Katherine B., Li, Huili, Murphy, Lauren M., Travers, Meghan E., Topper, Michael J., Mathios, Dimitrios, Lim, Michael, Shih, Ie-Ming, Wang, Tian-Li, Hung, Chien-Fu, Bhargava, Vipul, Wiehagen, Karla R., Cowley, Glenn S., Bachman, Kurtis E., Strick, Reiner, Strissel, Pamela L., Baylin, Stephen B., and Zahnow, Cynthia A.

Published
2018

2. Epigenetic therapy activates type I interferon signaling in murine ovarian cancer to reduce immunosuppression and tumor burden

Author

Stone, Meredith L., Chiappinelli, Katherine B., Li, Huili, Murphy, Lauren M., Travers, Meghan E., Topper, Michael J., Mathios, Dimitrios, Lim, Michael, Shih, Ie-Ming, Wang, Tian-Li, Hung, Chien-Fu, Bhargava, Vipul, Wiehagen, Karla R., Cowley, Glenn S., Bachman, Kurtis E., Strick, Reiner, Strissel, Pamela L., Baylin, Stephen B., and Zahnow, Cynthia A.

Published
2017

5. Memory B cell repertoire for recognition of evolving SARS-CoV-2 spike

Author

Tong, Pei, primary, Gautam, Avneesh, additional, Windsor, Ian W., additional, Travers, Meghan, additional, Chen, Yuezhou, additional, Garcia, Nicholas, additional, Whiteman, Noah B., additional, McKay, Lindsay G.A., additional, Storm, Nadia, additional, Malsick, Lauren E., additional, Honko, Anna N., additional, Lelis, Felipe J.N., additional, Habibi, Shaghayegh, additional, Jenni, Simon, additional, Cai, Yongfei, additional, Rennick, Linda J., additional, Duprex, W. Paul, additional, McCarthy, Kevin R., additional, Lavine, Christy L., additional, Zuo, Teng, additional, Lin, Junrui, additional, Zuiani, Adam, additional, Feldman, Jared, additional, MacDonald, Elizabeth A., additional, Hauser, Blake M., additional, Griffths, Anthony, additional, Seaman, Michael S., additional, Schmidt, Aaron G., additional, Chen, Bing, additional, Neuberg, Donna, additional, Bajic, Goran, additional, Harrison, Stephen C., additional, and Wesemann, Duane R., additional

Published
2021
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6. Quick COVID-19 Healers Sustain Anti-SARS-CoV-2 Antibody Production

Author

Chen, Yuezhou, primary, Zuiani, Adam, additional, Fischinger, Stephanie, additional, Mullur, Jyotsna, additional, Atyeo, Caroline, additional, Travers, Meghan, additional, Lelis, Felipe J.N., additional, Pullen, Krista M., additional, Martin, Hannah, additional, Tong, Pei, additional, Gautam, Avneesh, additional, Habibi, Shaghayegh, additional, Bensko, Jillian, additional, Gakpo, Deborah, additional, Feldman, Jared, additional, Hauser, Blake M., additional, Caradonna, Timothy M., additional, Cai, Yongfei, additional, Burke, John S., additional, Lin, Junrui, additional, Lederer, James A., additional, Lam, Evan Christopher, additional, Lavine, Christy L., additional, Seaman, Michael S., additional, Chen, Bing, additional, Schmidt, Aaron G., additional, Balazs, Alejandro Benjamin, additional, Lauffenburger, Douglas A., additional, Alter, Galit, additional, and Wesemann, Duane R., additional

Published
2020
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7. DNA vaccine protection against SARS-CoV-2 in rhesus macaques

Author

Yu, Jingyou, primary, Tostanoski, Lisa H., additional, Peter, Lauren, additional, Mercado, Noe B., additional, McMahan, Katherine, additional, Mahrokhian, Shant H., additional, Nkolola, Joseph P., additional, Liu, Jinyan, additional, Li, Zhenfeng, additional, Chandrashekar, Abishek, additional, Martinez, David R., additional, Loos, Carolin, additional, Atyeo, Caroline, additional, Fischinger, Stephanie, additional, Burke, John S., additional, Slein, Matthew D., additional, Chen, Yuezhou, additional, Zuiani, Adam, additional, Lelis, Felipe J. N., additional, Travers, Meghan, additional, Habibi, Shaghayegh, additional, Pessaint, Laurent, additional, Van Ry, Alex, additional, Blade, Kelvin, additional, Brown, Renita, additional, Cook, Anthony, additional, Finneyfrock, Brad, additional, Dodson, Alan, additional, Teow, Elyse, additional, Velasco, Jason, additional, Zahn, Roland, additional, Wegmann, Frank, additional, Bondzie, Esther A., additional, Dagotto, Gabriel, additional, Gebre, Makda S., additional, He, Xuan, additional, Jacob-Dolan, Catherine, additional, Kirilova, Marinela, additional, Kordana, Nicole, additional, Lin, Zijin, additional, Maxfield, Lori F., additional, Nampanya, Felix, additional, Nityanandam, Ramya, additional, Ventura, John D., additional, Wan, Huahua, additional, Cai, Yongfei, additional, Chen, Bing, additional, Schmidt, Aaron G., additional, Wesemann, Duane R., additional, Baric, Ralph S., additional, Alter, Galit, additional, Andersen, Hanne, additional, Lewis, Mark G., additional, and Barouch, Dan H., additional

Published
2020
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9. Abstract LB-022: Targeting glutamine metabolism as a mean of treating a murine model of ovarian cancer and ascites development

Author

Oh, Min-Hee, primary, Travers, Meghan, additional, Brown, Stephen, additional, Zhao, Liang, additional, Sun, Im-Meng, additional, Sun, Im-Hong, additional, Arwood, Matthew, additional, Xu, Wei, additional, Collins, Samuel, additional, Leone, Robert, additional, Prchalova, Eva, additional, Rais, Rana, additional, Slusher, Barbara, additional, Horton, Maureen, additional, Zahnow, Cynthia, additional, and Powell, Jonathan, additional

Published
2019
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10. DFMO and 5-Azacytidine Increase M1 Macrophages in the Tumor Microenvironment of Murine Ovarian Cancer

Author

Travers, Meghan, primary, Brown, Stephen M., additional, Dunworth, Matthew, additional, Holbert, Cassandra E., additional, Wiehagen, Karla R., additional, Bachman, Kurtis E., additional, Foley, Jackson R., additional, Stone, Meredith L., additional, Baylin, Stephen B., additional, Casero, Robert A., additional, and Zahnow, Cynthia A., additional

Published
2019
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11. The response of Escherichia coli to the alkylating agents chloroacetaldehyde and styrene oxide

Author

Muenter, Mark M., primary, Aiken, Ariel, additional, Akanji, Jadesola O., additional, Baig, Samir, additional, Bellou, Sirine, additional, Carlson, Alyssa, additional, Conway, Charles, additional, Cowell, Courtney M., additional, DeLateur, Nicholas A., additional, Hester, Alexis, additional, Joshi, Christopher, additional, Kramer, Caitlin, additional, Leifer, Becky S., additional, Nash, Emma, additional, Qi, Macee H., additional, Travers, Meghan, additional, Wong, Kelly C., additional, Hu, Man, additional, Gou, Na, additional, Giese, Roger W., additional, Gu, April Z., additional, and Beuning, Penny J., additional

Published
2019
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12. Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer

Author

Zhang, Hanghang, primary, Pandey, Somnath, additional, Travers, Meghan, additional, Sun, Hongxing, additional, Morton, George, additional, Madzo, Jozef, additional, Chung, Woonbok, additional, Khowsathit, Jittasak, additional, Perez-Leal, Oscar, additional, Barrero, Carlos A., additional, Merali, Carmen, additional, Okamoto, Yasuyuki, additional, Sato, Takahiro, additional, Pan, Joshua, additional, Garriga, Judit, additional, Bhanu, Natarajan V., additional, Simithy, Johayra, additional, Patel, Bela, additional, Huang, Jian, additional, Raynal, Noël J.-M., additional, Garcia, Benjamin A., additional, Jacobson, Marlene A., additional, Kadoch, Cigall, additional, Merali, Salim, additional, Zhang, Yi, additional, Childers, Wayne, additional, Abou-Gharbia, Magid, additional, Karanicolas, John, additional, Baylin, Stephen B., additional, Zahnow, Cynthia A., additional, Jelinek, Jaroslav, additional, Graña, Xavier, additional, and Issa, Jean-Pierre J., additional

Published
2018
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13. Abstract 2952: Targeting CDK9 reactivates epigenetically silenced genes in cancer

Author

Zhang, Hanghang, primary, Pandey, Somnath, additional, Travers, Meghan, additional, Khowsathit, Jittasak, additional, Morton, George, additional, Sum, Hongxing, additional, Barrero, Carlos A., additional, Merali, Carmen, additional, Okamoto, Yasuyuki, additional, Sato, Takahiro, additional, Garriga, Judit, additional, Bhanu, Natarajan V., additional, Simithy, Johayra, additional, Patel, Bela, additional, Madzo, Jozef, additional, Raynal, Noël, additional, Garcia, Benjamin A., additional, Jacobson, Marlene A., additional, Merali, Salim, additional, Zhang, Yi, additional, Childers, Wayne, additional, Abou-Gharbia, Magid, additional, Karanicolas, John, additional, Baylin, Stephen B., additional, Zahnow, Cynthia A., additional, Jelinek, Jaroslav, additional, Graña, Xavier, additional, and Issa, Jean-Pierre J., additional

Published
2018
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16. The Western Australian New Music Archive: performing as remembering

Author

Hope, Cat, MacKinney, Lisa, Green, Lelia, Travers, Meghan, and Mahoney, Tos

Subjects
archiving, digital preservation, digitisation, cultural studies, anthropology, PARADISEC
Abstract

The curation of WANMA is guided by, and confronts the challenges presented by, such a broad definition, with a focus on constructing a representative canon of Western Australian new music history from 1970 to the present day. A drawback of the Western Australian music collection at the State Library of Western Australia (SLWA), and indeed of many other Australian music collections (such as that at the Australian Music Centre and UWA’s Callaway Collection).

Published
2015

19. Genomic Analysis of the Resistance of E. coli to Benzyl Bromide

Author

Qi, Macee, primary, Muenter, Mark, additional, Baig, Samir, additional, Bellou, Sirine, additional, Carlson, Alyssa, additional, Conway, Charles, additional, Joshi, Christopher, additional, Kramer, Caitlin, additional, Leifer, Becky, additional, Travers, Meghan, additional, Wang, Poguang, additional, Giese, Roger, additional, and Beuning, Penny, additional

Published
2016
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20. Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity.

Author

Shrock, Ellen, Fujimura, Eric, Kula, Tomasz, Timms, Richard T., Lee, I-Hsiu, Leng, Yumei, Robinson, Matthew L., Sie, Brandon M., Li, Mamie Z., Chen, Yuezhou, Logue, Jennifer, Zuiani, Adam, McCulloch, Denise, Lelis, Felipe J. N., Henson, Stephanie, Monaco, Daniel R., Travers, Meghan, Habibi, Shaghayegh, Clarke, William A., and Caturegli, Patrizio

Published
2020
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21. REPLY TO HAFFNER ET AL.: DNA hypomethylation renders tumors moreimmunoqenic.

Author

Murphy, Lauren M., Travers, Meghan E., Topper, Michael J., Baylin, Stephen B., Zahnow, Cynthia A., Stone, Meredith L., Chiappinelli, Katherine B., Huili Li, Bachman, Kurtis E., Strick, Reiner, Strissel, Pamela L., Mathios, Dimitrios, Michael Lim, le-Ming Shih, Tian-Li Wang, Chien-Fu Hung, Bhargava, Vipul, Cowley, Glenn S., and Wiehagen, Karla R.

Subjects
*METHYLATION, *AZACITIDINE, *DNA methyltransferases
Published
2018
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22. Memory B cell repertoire for recognition of evolving SARS-CoV-2 spike.

Author

Tong P, Gautam A, Windsor I, Travers M, Chen Y, Garcia N, Whiteman NB, McKay LGA, Lelis FJN, Habibi S, Cai Y, Rennick LJ, Duprex WP, McCarthy KR, Lavine CL, Zuo T, Lin J, Zuiani A, Feldman J, MacDonald EA, Hauser BM, Griffths A, Seaman MS, Schmidt AG, Chen B, Neuberg D, Bajic G, Harrison SC, and Wesemann DR

Abstract

Memory B cell reserves can generate protective antibodies against repeated SARS-CoV-2 infections, but with an unknown reach from original infection to antigenically drifted variants. We charted memory B cell receptor-encoded monoclonal antibodies (mAbs) from 19 COVID-19 convalescent subjects against SARS-CoV-2 spike (S) and found 7 major mAb competition groups against epitopes recurrently targeted across individuals. Inclusion of published and newly determined structures of mAb-S complexes identified corresponding epitopic regions. Group assignment correlated with cross-CoV-reactivity breadth, neutralization potency, and convergent antibody signatures. mAbs that competed for binding the original S isolate bound differentially to S variants, suggesting the protective importance of otherwise-redundant recognition. The results furnish a global atlas of the S-specific memory B cell repertoire and illustrate properties conferring robustness against emerging SARS-CoV-2 variants., Competing Interests: Competing interests The authors declare no competing interests.

Published
2021
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23. The response of Escherichia coli to the alkylating agents chloroacetaldehyde and styrene oxide.

Author

Muenter MM, Aiken A, Akanji JO, Baig S, Bellou S, Carlson A, Conway C, Cowell CM, DeLateur NA, Hester A, Joshi C, Kramer C, Leifer BS, Nash E, Qi MH, Travers M, Wong KC, Hu M, Gou N, Giese RW, Gu AZ, and Beuning PJ

Subjects
Acetaldehyde pharmacology, DNA, Bacterial genetics, Esterases genetics, Rec A Recombinases genetics, Acetaldehyde analogs & derivatives, Alkylating Agents pharmacology, DNA Damage drug effects, Epoxy Compounds pharmacology, Escherichia coli drug effects, Escherichia coli genetics, SOS Response, Genetics genetics
Abstract

DNA damage is ubiquitous and can arise from endogenous or exogenous sources. DNA-damaging alkylating agents are present in environmental toxicants as well as in cancer chemotherapy drugs and are a constant threat, which can lead to mutations or cell death. All organisms have multiple DNA repair and DNA damage tolerance pathways to resist the potentially negative effects of exposure to alkylating agents. In bacteria, many of the genes in these pathways are regulated as part of the SOS reponse or the adaptive response. In this work, we probed the cellular responses to the alkylating agents chloroacetaldehyde (CAA), which is a metabolite of 1,2-dichloroethane used to produce polyvinyl chloride, and styrene oxide (SO), a major metabolite of styrene used in the production of polystyrene and other polymers. Vinyl chloride and styrene are produced on an industrial scale of billions of kilograms annually and thus have a high potential for environmental exposure. To identify stress response genes in E. coli that are responsible for tolerance to the reactive metabolites CAA and SO, we used libraries of transcriptional reporters and gene deletion strains. In response to both alkylating agents, genes associated with several different stress pathways were upregulated, including protein, membrane, and oxidative stress, as well as DNA damage. E. coli strains lacking genes involved in base excision repair and nucleotide excision repair were sensitive to SO, whereas strains lacking recA and the SOS gene ybfE were sensitive to both alkylating agents tested. This work indicates the varied systems involved in cellular responses to alkylating agents, and highlights the specific DNA repair genes involved in the responses., (Copyright © 2019 Elsevier B.V. All rights reserved.)

Published
2019
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