Search

Capacity assessment has been receiving special attention and development in many countries around the world as well as in Vietnam. This is considered a development step higher in the assessment of knowledge and skills. Assessing chemistry capacity through periodic tests will contribute to assessing students' chemistry ability through teaching Chemistry. Based on the requirements to be met as prescribed in the General Education Program in Chemistry to build a matrix of topics, a specification of test topics, from which it is possible to design different types of problems according to the matrix table. It is to assess the students' chemistry ability. This article illustrates the midterm exam I of Chemistry 10 according to the 2018 Program on the basis of consulting experts and colleagues. The test was also adjusted accordingly after assessing the difficulty, discriminant, and reliability. The results of pedagogical experiments with 82 grade 10 students in high schools were analyzed based on the expressions of 3 components of students' chemical competence. From there, it shows that the test has assessed the students' chemical ability, ensuring the goal of assessing students at the high school level.

Mục tiêu: mô tả tình trạng dinh dưỡng của bệnh nhân trước phẫu thuật và sau phẫu thuật có nuôi dưỡng kết hợp bằng sản phẩm suppro và cảm quan sản phẩm dinh dưỡng y học suppro. Phương pháp nghiên cứu: Can thiệp lâm sàng không đối chứng 30 bệnh nhân được nuôi dưỡng kết hợp sản phẩm Suppro tại bệnh viện Hữu Nghị Việt Đức từ 7/2022 - 9/2022. Kết quả: Tỷ lệ bệnh nhân suy dinh dưỡng có chỉ số BMI < 18,5 trước phẫu thuật là 10% sau phẫu thuật là 20%. 100% bệnh nhân sử dụng sản phẩm suppro thấy bột tơi mịn, thơm, vị dễ uống. Năng lượng nuôi dưỡng trung bình của bệnh nhân những ngày đầu sau phẫu thuật là 1195,3 ± 323 (kcal). Chỉ số albumin, prealbumin trung bình của bệnh nhân giảm sau phẫu thuật có ý nghĩa thống kê. Kết luận: Suppro có tính an toàn về màu sắc mùi vị cảm quan.

In this paper, a photonic crystal fiber (PCF) with core infiltrated with Nitrobenzene is proposed and investigated. Its feature properties as the effective refractive index, effective mode area, chromatic dispersion, and confinement loss have been numerically simulated. The obtained results show that characteristic quantities of PCF with core infiltrated with Nitrobenzene (PCF-N) having some advantages in comparison to PCF with core infiltrated with Toluene (PCF-T) at 1.55μm wavelength. For the purpose of supercontinuum generation, two optimal structures with lattice constants 2.0μm and 2.5μm with filling factors d/Ʌ = 0.3 are identified.

Upon invading the host erythrocyte, the human malaria parasite P. falciparum lives and replicates within a membrane bound compartment referred to as the parasitophorous vacuole. Recently, interest in this compartment and its protein content has grown, due to the important roles these play in parasite egress and protein traffic to the host cell. Surprisingly, the function of many proteins within this compartment has not been experimentally addressed. Here, we study the importance of one of these proteins, termed PfPV1, for intra-erythrocytic parasite survival. Despite numerous attempts to inactivate the gene encoding PfPV1, we were unable to recover deletion mutants. Control experiments verified that the pv1 gene locus was per se open for gene targeting experiments, allowing us to exclude technical limitations in our experimental strategy. Our data provide strong genetic evidence that PfPV1 is essential for survival of blood stage P. falciparum, and further highlight the importance of parasitophorous vacuole proteins in this part of the parasite's life cycle.

Many apicomplexan parasites, including Plasmodium falciparum , harbor a so-called apicoplast, a complex plastid of red algal origin which was gained by a secondary endosymbiotic event. The exact molecular mechanisms directing the transport of nuclear-encoded proteins to the apicoplast of P. falciparum are not well understood. Recently, in silico analyses revealed a second copy of proteins homologous to components of the endoplasmic reticulum (ER)-associated protein degradation (ERAD) system in organisms with secondary plastids, including the malaria parasite P. falciparum . These proteins are predicted to be endowed with an apicoplast targeting signal and are suggested to play a role in the transport of nuclear-encoded proteins to the apicoplast. Here, we have studied components of this ERAD-derived putative preprotein translocon complex in malaria parasites. Using transfection technology coupled with fluorescence imaging techniques we can demonstrate that the N terminus of several ERAD-derived components targets green fluorescent protein to the apicoplast. Furthermore, we confirm that full-length PfsDer1-1 and PfsUba1 (homologues of yeast ERAD components) localize to the apicoplast, where PfsDer1-1 tightly associates with membranes. Conversely, PfhDer1-1 (a host-specific copy of the Der1-1 protein) localizes to the ER. Our data suggest that ERAD components have been “rewired” to provide a conduit for protein transport to the apicoplast. Our results are discussed in relation to the nature of the apicoplast protein transport machinery.