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Your search keyword '"Towhid, Syeda Tasneem"' showing total 28 results
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28 results on '"Towhid, Syeda Tasneem"'

2. Wastewater to clinical case (WC) ratio of COVID-19 identifies insufficient clinical testing, onset of new variants of concern and population immunity in urban communities

Author

D'Aoust, Patrick M., Tian, Xin, Towhid, Syeda Tasneem, Xiao, Amy, Mercier, Elisabeth, Hegazy, Nada, Jia, Jian-Jun, Wan, Shen, Kabir, Md Pervez, Fang, Wanting, Fuzzen, Meghan, Hasing, Maria, Yang, Minqing Ivy, Sun, Jianxian, Plaza-Diaz, Julio, Zhang, Zhihao, Cowan, Aaron, Eid, Walaa, Stephenson, Sean, Servos, Mark R., Wade, Matthew J., MacKenzie, Alex E., Peng, Hui, Edwards, Elizabeth A., Pang, Xiao-Li, Alm, Eric J., Graber, Tyson E., and Delatolla, Robert

Published
2022
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6. Impact of coagulation on SARS-CoV-2 and PMMoV viral signal in wastewater solids

Author

Hegazy, Nada, primary, Tian, Xin, additional, D’Aoust, Patrick M., additional, Pisharody, Lakshmi, additional, Towhid, Syeda Tasneem, additional, Mercier, Élisabeth, additional, Zhang, Zhihao, additional, Wan, Shen, additional, Thakali, Ocean, additional, Kabir, Md Pervez, additional, Fang, Wanting, additional, Nguyen, Tram B., additional, Ramsay, Nathan T., additional, MacKenzie, Alex E., additional, Graber, Tyson E., additional, Guilherme, Stéphanie, additional, and Delatolla, Robert, additional

Published
2023
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8. Wastewater to clinical case (WC) ratio of COVID-19 identifies insufficient clinical testing, onset of new variants of concern and population immunity in urban communities

Author

Massachusetts Institute of Technology. Department of Biological Engineering, D'Aoust, Patrick M, Tian, Xin, Towhid, Syeda Tasneem, Xiao, Amy, Mercier, Elisabeth, Hegazy, Nada, Jia, Jian-Jun, Wan, Shen, Kabir, Md Pervez, Fang, Wanting, Fuzzen, Meghan, Hasing, Maria, Yang, Minqing Ivy, Sun, Jianxian, Plaza-Diaz, Julio, Zhang, Zhihao, Cowan, Aaron, Eid, Walaa, Stephenson, Sean, Servos, Mark R, Wade, Matthew J, MacKenzie, Alex E, Peng, Hui, Edwards, Elizabeth A, Pang, Xiao-Li, Alm, Eric J, Graber, Tyson E, Delatolla, Robert, Massachusetts Institute of Technology. Department of Biological Engineering, D'Aoust, Patrick M, Tian, Xin, Towhid, Syeda Tasneem, Xiao, Amy, Mercier, Elisabeth, Hegazy, Nada, Jia, Jian-Jun, Wan, Shen, Kabir, Md Pervez, Fang, Wanting, Fuzzen, Meghan, Hasing, Maria, Yang, Minqing Ivy, Sun, Jianxian, Plaza-Diaz, Julio, Zhang, Zhihao, Cowan, Aaron, Eid, Walaa, Stephenson, Sean, Servos, Mark R, Wade, Matthew J, MacKenzie, Alex E, Peng, Hui, Edwards, Elizabeth A, Pang, Xiao-Li, Alm, Eric J, Graber, Tyson E, and Delatolla, Robert

Abstract

Clinical testing has been the cornerstone of public health monitoring and infection control efforts in communities throughout the COVID-19 pandemic. With the anticipated reduction of clinical testing as the disease moves into an endemic state, SARS-CoV-2 wastewater surveillance (WWS) will have greater value as an important diagnostic tool. An in-depth analysis and understanding of the metrics derived from WWS is required to interpret and utilize WWS-acquired data effectively (McClary-Gutierrez et al., 2021; O'Keeffe, 2021). In this study, the SARS-CoV-2 wastewater signal to clinical cases (WC) ratio was investigated across seven cities in Canada over periods ranging from 8 to 21 months. This work demonstrates that significant increases in the WC ratio occurred when clinical testing eligibility was modified to appointment-only testing, identifying a period of insufficient clinical testing (resulting in a reduction to testing access and a reduction in the number of daily tests) in these communities, despite increases in the wastewater signal. Furthermore, the WC ratio decreased significantly in 6 of the 7 studied locations, serving as a potential signal of the emergence of the Alpha variant of concern (VOC) in a relatively non-immunized community (40-60 % allelic proportion), while a more muted decrease in the WC ratio signaled the emergence of the Delta VOC in a relatively well-immunized community (40-60 % allelic proportion). Finally, a significant decrease in the WC ratio signaled the emergence of the Omicron VOC, likely because of the variant's greater effectiveness at evading immunity, leading to a significant number of new reported clinical cases, even when community immunity was high. The WC ratio, used as an additional monitoring metric, could complement clinical case counts and wastewater signals as individual metrics in its potential ability to identify important epidemiological occurrences, adding value to WWS as a diagnostic technology during the COVID-19

Published
2023

12. Understanding the dynamic relation between wastewater SARS-CoV-2 signal and clinical metrics throughout the pandemic

Author

Hegazy, Nada, primary, Cowan, Aaron, additional, D’Aoust, Patrick M., additional, Mercier, Élisabeth, additional, Towhid, Syeda Tasneem, additional, Jia, Jian-Jun, additional, Wan, Shen, additional, Zhang, Zhihao, additional, Kabir, Md Pervez, additional, Fang, Wanting, additional, Graber, Tyson E., additional, MacKenzie, Alex E., additional, Guilherme, Stéphanie, additional, and Delatolla, Robert, additional

Published
2022
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15. Wastewater to clinical case (WC) ratio of COVID-19 identifies insufficient clinical testing, onset of new variants of concern and population immunity in urban communities

Author

D’Aoust, Patrick M., primary, Tian, Xin, additional, Towhid, Syeda Tasneem, additional, Xiao, Amy, additional, Mercier, Elisabeth, additional, Hegazy, Nada, additional, Jia, Jian-Jun, additional, Wan, Shen, additional, Kabir, Md Pervez, additional, Fang, Wanting, additional, Fuzzen, Meghan, additional, Hasing, Maria, additional, Yang, Minqing Ivy, additional, Sun, Jianxian, additional, Plaza-Diaz, Julio, additional, Zhang, Zhihao, additional, Cowan, Aaron, additional, Eid, Walaa, additional, Stephenson, Sean, additional, Servos, Mark R., additional, Wade, Matthew J., additional, MacKenzie, Alex E., additional, Peng, Hui, additional, Edwards, Elizabeth A., additional, Pang, Xiao-Li, additional, Alm, Eric J., additional, Graber, Tyson E., additional, and Delatolla, Robert, additional

Published
2022
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18. Near real-time determination of B.1.1.7 in proportion to total SARS-CoV-2 viral load in wastewater using an allele-specific primer extension PCR strategy

Author

Graber, Tyson E., primary, Mercier, Élisabeth, additional, Bhatnagar, Kamya, additional, Fuzzen, Meghan, additional, D’Aoust, Patrick M., additional, Hoang, Huy-Dung, additional, Tian, Xin, additional, Towhid, Syeda Tasneem, additional, Diaz, Julio Plaza, additional, Alain, Tommy, additional, Butler, Ainslie, additional, Goodridge, Lawrence, additional, Servos, Mark, additional, and Delatolla, Robert, additional

Published
2021
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27. Thymoquinone‐induced platelet apoptosis

Author

Towhid, Syeda Tasneem, primary, Schmidt, Eva‐Maria, additional, Schmid, Evi, additional, Münzer, Patrick, additional, Qadri, Syed M., additional, Borst, Oliver, additional, and Lang, Florian, additional

Published
2011
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28. Draft whole-genome sequence of Enterococcus faecium isolate from a clinical sample from Dhaka, Bangladesh.

Author

Towhid ST, Shihab MMR, Jubair M, Faisal NI, and Rahman MM

Abstract

We collected a urine specimen from a 20-year-old male, cultured it on Chrom-agar Enterococcus , identified it with VITEK2, and whole-genome sequenced it using the PacBio RSII. The genome was 3,111,621 nucleotides long with a GC% of 37.6%. It was identified as a human pathogen with a 92.3% probability and is available on NCBI with an accession ID of JBFBPS000000000.1.

Published
2024
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