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23 results on '"Touzani, Alae"'

1. MRI lesion size is more important than the number of positive biopsy cores in predicting adverse features and recurrence after radical prostatectomy: implications for active surveillance criteria in intermediate-risk patients

Author

Baboudjian, Michael, Uleri, Alessandro, Beauval, Jean-Baptiste, Touzani, Alae, Diamand, Romain, Roche, Jean-Baptiste, Lacetera, Vito, Lechevallier, Eric, Roumeguère, Thierry, Simone, Giuseppe, Benamran, Daniel, Fourcade, Alexandre, Fiard, Gaelle, Peltier, Alexandre, and Ploussard, Guillaume

Published
2024
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4. Expanding inclusion criteria for active surveillance in intermediate-risk prostate cancer: a machine learning approach

Author

Baboudjian, Michael, Breda, Alberto, Roumeguère, Thierry, Uleri, Alessandro, Roche, Jean-Baptiste, Touzani, Alae, Lacetera, Vito, Beauval, Jean-Baptiste, Diamand, Romain, Simone, Guiseppe, Windisch, Olivier, Benamran, Daniel, Fourcade, Alexandre, Fiard, Gaelle, Durand-Labrunie, Camille, Roumiguié, Mathieu, Sanguedolce, Francesco, Oderda, Marco, Barret, Eric, Fromont, Gaëlle, Dariane, Charles, Charvet, Anne-Laure, Gondran-Tellier, Bastien, Bastide, Cyrille, Lechevallier, Eric, Palou, Joan, Ruffion, Alain, Van Der Bergh, Roderick C. N., Peltier, Alexandre, and Ploussard, Guillaume

Published
2023
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5. Robot-assisted Radical Cystectomy with Orthotopic Neobladder Reconstruction: Techniques and Functional Outcomes in Males

Author

Martini, Alberto, Falagario, Ugo Giovanni, Russo, Antonio, Mertens, Laura S., Di Gianfrancesco, Luca, Bravi, Carlo Andrea, Vollemaere, Jonathan, Abdeen, Muhammad, Mendrek, Mikolaj, Kjøbli, Eirik, Buse, Stephan, Wijburg, Carl, Touzani, Alae, Ploussard, Guillaume, Antonelli, Alessandro, Schwenk, Laura, Ebbing, Jan, Vasdev, Nikhil, Froelicher, Gabriel, John, Hubert, Canda, Abdullah Erdem, Balbay, Mevlana Derya, Stoll, Marcel, Edeling, Sebastian, Witt, Jorn H., Leyh-Bannurah, Sami-Ramzi, Siemer, Stefan, Stoeckle, Michael, Mottrie, Alexander, D'Hondt, Frederiek, Crestani, Alessandro, Porreca, Angelo, van der Poel, Hendrik, Decaestecker, Karel, Gaston, Richard, Peter Wiklund, N., and Hosseini, Abolfazl

Published
2023
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7. Magnetic Resonance Imaging–based T-staging to Predict Biochemical Recurrence after Radical Prostatectomy: A Step Towards the iTNM Classification

Author

Baboudjian, Michael, Gondran-Tellier, Bastien, Touzani, Alae, Martini, Alberto, Diamand, Romain, Roche, Jean-Baptiste, Lacetera, Vito, Beauval, Jean-Baptiste, Roumeguère, Thierry, Simone, Guiseppe, Benamran, Daniel, Fourcade, Alexandre, Fiard, Gaelle, van den Bergh, Roderick C.N., Peltier, Alexandre, and Ploussard, Guillaume

Published
2023
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8. Correction to: Overdiagnosis and stage migration of ISUP 2 disease due to mpMRI-targeted biopsy: facts or fictions

Author

Martini, Alberto, Touzani, Alae, Mazzone, Elio, Roumiguié, Mathieu, Marra, Giancarlo, Valerio, Massimo, Beauval, Jean Baptiste, Campi, Riccardo, Minervini, Andrea, van den Berg, Roderick C. N., Soeterik, Timo F. W., Zhuang, Junlong, Guo, Hongqian, Gontero, Paolo, Montorsi, Francesco, Briganti, Alberto, Gandaglia, Giorgio, and Ploussard, Guillame

Published
2023
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9. Heterogeneity of contemporary grade group 4 prostate cancer in radical prostatectomy specimens

Author

Martini, Alberto, Touzani, Alae, Beauval, Jean-Baptiste, Ruffion, Alain, Olivier, Jonathan, Gasmi, Anis, Dariane, Charles, Thoulouzan, Matthieu, Barret, Eric, Brureau, Laurent, Créhange, Gilles, Fiard, Gaëlle, Gauthé, Mathieu, Renard-Penna, Raphaële, Roubaud, Guilhem, Sargos, Paul, Roumiguié, Mathieu, Timsit, Marc-Olivier, Mathieu, Romain, Villers, Arnauld, Rouprêt, Morgan, Fromont, Gaëlle, and Ploussard, Guillaume

Published
2022
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10. Grade group 1 prostate cancer on biopsy: are we still missing aggressive disease in the era of image-directed therapy?

Author

Baboudjian, Michael, Roumiguié, Mathieu, Peltier, Alexandre, Oderda, Marco, Barret, Eric, Fromont, Gaëlle, Dariane, Charles, Fiard, Gaelle, Charvet, Anne-Laure, Gondran-Tellier, Bastien, Durand-Labrunie, Camille, Campello, Pierre Vincent, Roumeguère, Thierry, Diamand, Romain, Diana, Pietro, Touzani, Alae, Beauval, Jean-Baptiste, Daniel, Laurent, Rouprêt, Morgan, Ruffion, Alain, and Ploussard, Guillaume

Published
2022
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11. One‐year outcomes of same‐day‐discharge robot‐assisted radical prostatectomy

Author

Touzani, Alae, primary, D'Agate, Daniele, additional, Kesch, Claudia, additional, Calleris, Giorgio, additional, Buhas, Bogdan, additional, Abou‐Zahr, Rawad, additional, Rahota, Razvan‐George, additional, Ouzzane, Adil, additional, Pradère, Benjamin, additional, Tollon, Christophe, additional, Martini, Alberto, additional, and Ploussard, Guillaume, additional

Published
2024
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12. Overdiagnosis and stage migration of ISUP 2 disease due to mpMRI-targeted biopsy: facts or fictions

Author

Martini, Alberto, Touzani, Alae, Mazzone, Elio, Roumiguié, Mathieu, Marra, Giancarlo, Valerio, Massimo, Beauval, Jean Baptiste, Campi, Riccardo, Minervini, Andrea, van den Berg, Roderick C. N., Soeterik, Timo F. W., Zhuang, Junlong, Guo, Hongqian, Gontero, Paolo, Montorsi, Francesco, Briganti, Alberto, Gandaglia, Giorgio, and Ploussard, Guillame

Published
2022
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13. How can we reduce morbidity after robot‐assisted radical cystectomy with intracorporeal neobladder? A report on postoperative complications by the European Association of Urology Robotic Urology Section Scientific Working Group.

Author

Pellegrino, Francesco, Martini, Alberto, Falagario, Ugo Giovanni, Rautiola, Juhana, Russo, Antonio, Mertens, Laura S, Di Gianfrancesco, Luca, Bravi, Carlo Andrea, Vollemaere, Jonathan, Abdeen, Muhammad, Moschini, Marco, Mendrek, Mikolaj, Kjøbli, Eirik, Buse, Stephan, Wijburg, Carl, Touzani, Alae, Ploussard, Guillaume, Antonelli, Alessandro, Schwenk, Laura, and Ebbing, Jan

Subjects
URINARY diversion, ILEAL conduit surgery, SURGICAL complications, CYSTECTOMY, SURGICAL robots, UROLOGY, ENHANCED recovery after surgery protocol
Abstract

A study published in BJU International examined the complications associated with robot-assisted radical cystectomy (RARC) with intracorporeal neobladder reconstruction. The study analyzed data from 858 patients who underwent the procedure at 16 European centers between 2003 and 2022. The results showed a high overall rate of complications, with urinary tract infection (UTI) being the most common complication. The study highlighted the need for improvements in surgical technique and peri-operative management to reduce complications. The findings also suggested the importance of careful management of the urinary device and consideration of neoadjuvant therapy in patient care. [Extracted from the article]

Published
2024
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15. Oncological outcomes of radical prostatectomy in very high-risk patients according to STAMPEDE criteria: does local treatment alone still have a place in the era of intensified systemic therapies?

Author

BABOUDJIAN, Michael, primary, TOUZANI, Alae, additional, MARTINI, Alberto, additional, DIAMAND, Romain, additional, ROCHE, Jean B., additional, LACETERA, Vito, additional, BEAUVAL, Jean B., additional, GONDRAN-TELLIER, Bastien, additional, ROUMEGUÈRE, Thierry, additional, SIMONE, Guiseppe, additional, WINDISCH, Olivier, additional, BENAMRAN, Daniel, additional, FOURCADE, Alexandre, additional, FIARD, Gaelle, additional, VAN DEN BERGH, Roderick C., additional, PELTIER, Alexandre, additional, and PLOUSSARD, Guillaume, additional

Published
2023
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16. Clinical Trial Protocol for PERFECT: A Randomised Controlled Trial Comparing the Efficiency and Tolerance of Transperineal Fusion Versus Transrectal Imaging-targeted Prostate Biopsies (CCAFU-PR1 Study)

Author

Touzani, Alae, primary, Fiard, Gaëlle, additional, Barret, Eric, additional, Renard-Penna, Raphaële, additional, Salin, Ambroise, additional, Pradère, Benjamin, additional, Rozet, François, additional, Beauval, Jean-Baptiste, additional, Malavaud, Bernard, additional, Giannarini, Gianluca, additional, Colin, Pierre, additional, Rouprêt, Morgan, additional, and Ploussard, Guillaume, additional

Published
2022
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17. MRI lesion size is more important than the number of positive biopsy cores in predicting adverse features and recurrence after radical prostatectomy: implications for active surveillance criteria in intermediate-risk patients

Author

Baboudjian, Michael, Uleri, Alessandro, Beauval, Jean-Baptiste, Touzani, Alae, Diamand, Romain, Roche, Jean-Baptiste, Lacetera, Vito, Lechevallier, Eric, Roumeguère, Thierry, Simone, Giuseppe, Benamran, Daniel, Fourcade, Alexandre, Fiard, Gaelle, Peltier, Alexandre, and Ploussard, Guillaume

Abstract

Introduction: To determine associations between prostate cancer (PCa) tumor burden measured on biopsy or multiparametric magnetic resonance imaging (mpMRI) and outcomes in intermediate-risk (IR) International Society of Urological Pathology (ISUP) grade 2 men managed with primary radical prostatectomy (RP). Methods: This retrospective, multicenter study was conducted in eight referral centers. The cohort included IR PCa patients who had ISUP 2 at biopsy. We defined biopsy tumor burden as low/high based on the absence/presence of more than 25% positive cores. Tumor burden on imaging was defined as low/high based on maximum lesion diameter, <15 mm and ≥15 mm at mpMRI, respectively. The histological endpoint of the study was adverse features at RP, defined as ≥pT3a stage and/or lymph node invasion and/or ISUP ≥3 at final pathology. The clinical endpoint was biochemical recurrence (BCR) after RP. Results: A total of 698 IR patients was included, of whom 335 (48%) had adverse features. In multivariate logistic regression analysis, there was no statistical association between tumor burden at biopsy and adverse features (p= 0.7). Tumor size ≥15 mm at mpMRI was significantly associated with adverse pathology (OR 1.65, 95%CI 1.14–2.39; p= 0.01). No significant association was observed between tumor burden at biopsy and BCR (p= 0.4). Tumor size ≥15 mm at mpMRI was significantly associated with BCR (HR 1.96, 95% CI 1.01–3.80; p= 0.04). Conclusions: Our data support extending the inclusion criteria to ISUP 2 men with >25% positive cores, provided they have a low tumor size at mpMRI (<15 mm). Prospective studies should be performed to validate these findings.

Published
2023
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18. Cystitis Glandularis: A Rare Benign Condition Presenting as Bladder Tumor

Author

Youness Jabbour, Jacquet Djamal, Kadir El Khader, Ahmed Ibn Attiya Andaloussi, Tariq Karmouni, Touzani Alae, Sumba Harrison, Hamza Lamchahab, and Abdelatif Koutani

Subjects
medicine.medical_specialty, education.field_of_study, Urinary bladder, Glandular metaplasia, medicine.diagnostic_test, business.industry, Population, Context (language use), Cystoscopy, medicine.disease, Dermatology, medicine.anatomical_structure, Lower urinary tract symptoms, Metaplasia, medicine, medicine.symptom, business, education, Cystitis glandularis
Abstract

Cystitis glandularis or glandular metaplasia of the urinary bladder, is a benignreactive metaplasia of the urothelium, which occurs in the context of chronic irritation, in less than 2% of the general population. It is a condition in most casesasymptomatic, but also characterized by nonspecific symptoms and paraclinical findings, which is why this condition is underdiagnosed. Its evolution is mainly focused on the risk of malignant degeneration. This condition affects men much more commonly than women. Two forms of cystitis glandularis are recognized: typical and intestinal form. They differ in their histology, incidence, difficulty of diagnosis, and possible association with adenocarcinoma of the bladder. Diagnosis of certainty is histological by careful analysis of chips from bladder endoscopic resection. This rare pathology is managed by endoscopic bladder resection, with repeated cystoscopy as a monitoring tool. Extensive surgical is needed in severe or recurrent cases. We present here-in a case of a female patient having cystitis glandularis presenting with lower urinary tract symptoms. We review equally data reported in literature. To the best of our knowledge our case represents the fourth case of cystitis glandularis affecting a female patient reported in the English literature so far.

Published
2018

20. Association of Prostate Cancer with Nuts, Seeds, Alcohol and Processed Meats: A Worldwide Population-Based Study.

Author

Ziouziou, Imad, Touzani, Alae M., Lahlou, Laila, Shariat, Shahrokh F., Sanguedolce, Francesco, Neuzillet, Yann, Ajdi, Farida, and Khabbal, Youssef

Subjects
*STATISTICS, *MEAT, *MULTIPLE regression analysis, *DISEASE incidence, *ECOLOGICAL research, *INGESTION, *DIET, *RISK assessment, *SEEDS, *ALCOHOL drinking, *DISEASE prevalence, *DESCRIPTIVE statistics, *PROSTATE tumors, *NUTS, *DISEASE risk factors
Abstract

There are conflicting data with regards to the link between diet and the prostate cancer. The purpose of this study was to assess the association of dietary factors with incidence, prevalence and mortality rates of prostate cancer worldwide. We conducted an ecological study including 170 countries, whose data on incidence, prevalence and mortality rates of prostate cancer, dietary factors, and potentially confounding factors were available and collected in May 2020. Univariable and multivariable linear regression analyses were used. Consumption of nuts and seeds was inversely associated with incidence, prevalence and mortality rates of prostate cancer (β −0.7, P < 0.001; β −2.1, P < 0.001; β −0.1, P = 0.02; respectively). Intake of alcohol was associated with increased incidence, prevalence and mortality rates of prostate cancer (β 1.8, P < 0.001; β 4.5, P < 0.001; β 0.4, P < 0.001; respectively). Consumption of processed meats was also associated with increased incidence and prevalence rates of prostate cancer (β 0.6, P = 0.003; β 2.8, P = 0.001; respectively). These data suggest that consumption of nuts and seeds have a protective effect against prostate carcinogenesis, progression, and metastasis, while alcohol and processed meat increase these risks. [ABSTRACT FROM AUTHOR]

Published
2021
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22. Bilateral kidney matrix stones: a rare case

Author

Lahyani, Mounir, primary, Rhannam, Yassine, additional, Slaoui, Amine, additional, Touzani, Alae, additional, Karmouni, Tarik, additional, Elkhader, Khalid, additional, Koutani, Abdellatif, additional, and attya, Ahmed Ibn, additional

Published
2016
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23. [Isolated male epispadias].

Author

Othmane Y and Touzani A

Subjects
Abdominal Wall, Adult, Epispadias pathology, Epispadias surgery, Humans, Male, Treatment Outcome, Urethra surgery, Urogenital Surgical Procedures methods, Dysuria etiology, Epispadias diagnosis, Penis abnormalities, Urethra abnormalities
Abstract

Epispadias is a rare urogenital malformation characterized by more or less complete aplasia of the upper part of the urethra. It is commonly associated with bladder exstrophy. Isolated epispadias occurs in 10% of cases. Continent and incontinent epispadias may be distinguished. We report the case of a 29-year old patient presenting with dysuria associated with the impossibility of having sexual intercourses. Physical examination of the external genitalia showed slit-like abnormal urethral opening on the distal half of the dorsal side of the penis. Patient's penis didn't have dorsal curvature (chordee), the corpus cavernosum was palpated and slightly lateralized. The abdominal wall was without abnormalities. The remainder of the clinical examination was normal. Given this anomaly, the diagnosis of balano-pubic continent epispadias was retained. Ultrasound of the urinary tract was normal and pelvis X-ray without preparation showed interpubic diastasis. The patient underwent single-stage surgery using Cantwell-Young technique. Immediate postoperative outcome was without abnormalities; the urethral probe was removed 21 days later, after wound healing. Functional and aesthetics outcome evaluated at three and six months was satisfactory without penis shortness.

Published
2017
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