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1. The LSPE-Strip feed horn array

Author

Franceschet, C., Del Torto, F., Villa, F., Realini, S., Bongiolatti, R., Peverini, O. A., Pezzotta, F., Viganó, D. M., Addamo, G., Bersanelli, M., Cavaliere, F., Cuttaia, F., Gervasi, M., Mennella, A., Morgante, G., Taylor, A. C., Virone, G., and Zannoni, M.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

In this paper we discuss the design, manufacturing and characterization of the feed horn array of the Strip instrument of the Large Scale Polarization Explorer (LSPE) experiment. Strip is a microwave telescope, operating in the Q- and W-band, for the observation of the polarized emissions from the sky in a large fraction (about 37%) of the Northern hemisphere with subdegree angular resolution. The Strip focal plane is populated by forty-nine Q-band and six W-band corrugated horns, each feeding a cryogenically cooled polarimeter for the detection of the Stokes $Q$ and $U$ components of the polarized signal from the sky. The Q-band channel is designed to accurately monitor Galactic polarized synchrotron emission, while the combination of Q- and W-band will allow the study of atmospheric effects at the observation site, the Observatorio del Teide, in Tenerife. In this paper we focus on the development of the Strip corrugated feed horns, including design requirements, engineering and manufacturing, as well as detailed characterization and performance verification., Comment: Version 1: This paper (28 pages, 25 figures) is part of the Special Issue "The LSPE/Strip instrument description and testing", being submitted to JINST. Version 2: Added new references. Splitting of design and specifications tables in Sec. 2.1. Other minor revisions included

Published
2021
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3. Progress report on the Large Scale Polarization Explorer

Author

Lamagna, L., Addamo, G., Ade, P. A. R., Baccigalupi, C., Baldini, A. M., Battaglia, P. M., Battistelli, E., Baù, A., Bersanelli, M., Biasotti, M., Boragno, C., Boscaleri, A., Caccianiga, B., Caprioli, S., Cavaliere, F., Cei, F., Cleary, K. A., Columbro, F., Coppi, G., Coppolecchia, A., Corsini, D., Cuttaia, F., D'Alessandro, G., de Bernardis, P., De Gasperis, G., De Petris, M., Del Torto, F., Fafone, V., Farooqui, Z., Farsian, F., Fontanelli, F., Franceschet, C., Gaier, T. C., Gatti, F., Genova-Santos, R., Gervasi, M., Ghigna, T., Grassi, M., Grosso, D., Gualtieri, R., Incardona, F., Jones, M., Kangaslahti, P., Krachmalnicoff, N., Mainini, R., Maino, D., Mandelli, S., Maris, M., Masi, S., Matarrese, S., May, A., Mena, P., Mennella, A., Molina, R., Molinari, D., Morgante, G., Nati, F., Natoli, P., Pagano, L., Paiella, A., Paonessa, F., Passerini, A., Perez-de-Taoro, M., Peverini, O. A., Pezzotta, F., Piacentini, F., Piccirillo, L., Pisano, G., Polastri, L., Polenta, G., Poletti, D., Presta, G., Realini, S., Reyes, N., Rocchi, A., Rubiño-Martin, J. A., Sandri, M., Sartor, S., Schillaci, A., Signorelli, G., Siri, B., Soria, M., Spinella, F., Tapia, V., Tartari, A., Taylor, A., Terenzi, L., Tomasi, M., Tommasi, E., Tucker, C., Vaccaro, D., Vigano, D. M., Villa, F., Virone, G., Vittorio, N., Volpe, A., Watkins, B., Zacchei, A., and Zannoni, M.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

The Large Scale Polarization Explorer (LSPE) is a cosmology program for the measurement of large scale curl-like features (B-modes) in the polarization of the Cosmic Microwave Background. Its goal is to constrain the background of inflationary gravity waves traveling through the universe at the time of matter-radiation decoupling. The two instruments of LSPE are meant to synergically operate by covering a large portion of the northern microwave sky. LSPE/STRIP is a coherent array of receivers planned to be operated from the Teide Observatory in Tenerife, for the control and characterization of the low-frequency polarized signals of galactic origin; LSPE/SWIPE is a balloon-borne bolometric polarimeter based on 330 large throughput multi-moded detectors, designed to measure the CMB polarization at 150 GHz and to monitor the polarized emission by galactic dust above 200 GHz. The combined performance and the expected level of systematics mitigation will allow LSPE to constrain primordial B-modes down to a tensor/scalar ratio of $10^{-2}$. We here report the status of the STRIP pre-commissioning phase and the progress in the characterization of the key subsystems of the SWIPE payload (namely the cryogenic polarization modulation unit and the multi-moded TES pixels) prior to receiver integration., Comment: 8 pages, 5 figures, Accepted for publication in Journal of Low Temperature Physics

Published
2020
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4. The STRIP instrument of the Large Scale Polarization Explorer: microwave eyes to map the Galactic polarized foregrounds

Author

Franceschet, C., Realini, S., Mennella, A., Addamo, G., Baù, A., Battaglia, P. M., Bersanelli, M., Caccianiga, B., Caprioli, S., Cavaliere, F., Cleary, K. A., Cuttaia, F., Del Torto, F., Fafone, V., Farooqui, Z., Santos, R. T. Génova, Gaier, T. C., Gervasi, M., Ghigna, T., Incardona, F., Iovenitti, S., Jones, M., Kangaslahti, P., Mainini, R., Maino, D., Maris, M., Mena, P., Molina, R., Morgante, G., Passerini, A., Perez-de-Taoro, M., Peverini, O. A., Pezzotta, F., Pincella, C., Reyes, N., Rocchi, A., Rubiño-Martín, J. A., Sandri, M., Sartor, S., Soria, M., Tapia, V., Terenzi, L., Tomasi, M., Tommasi, E., Viganó, D. M., Villa, F., Virone, G., Volpe, A., Watkins, B., Zacchei, A., and Zannoni, M.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

In this paper we discuss the latest developments of the STRIP instrument of the "Large Scale Polarization Explorer" (LSPE) experiment. LSPE is a novel project that combines ground-based (STRIP) and balloon-borne (SWIPE) polarization measurements of the microwave sky on large angular scales to attempt a detection of the "B-modes" of the Cosmic Microwave Background polarization. STRIP will observe approximately 25% of the Northern sky from the "Observatorio del Teide" in Tenerife, using an array of forty-nine coherent polarimeters at 43 GHz, coupled to a 1.5 m fully rotating crossed-Dragone telescope. A second frequency channel with six-elements at 95 GHz will be exploited as an atmospheric monitor. At present, most of the hardware of the STRIP instrument has been developed and tested at sub-system level. System-level characterization, starting in July 2018, will lead STRIP to be shipped and installed at the observation site within the end of the year. The on-site verification and calibration of the whole instrument will prepare STRIP for a 2-years campaign for the observation of the CMB polarization., Comment: 17 pages, 15 figures, proceedings of the SPIE Astronomical Telescopes + Instrumentation conference "Millimeter, Submillimeter, and Far-Infrared Detectors and Instrumentation for Astronomy IX", on June 15th, 2018, Austin (TX)

Published
2018
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6. QUBIC - The Q&U Bolometric Interferometer for Cosmology - A novel way to look at the polarized Cosmic Microwave Background

Author

Mennella, A., Ade, P. A. R., Aumont, J., Banfi, S., Battaglia, P., Battistelli, E. S., Baù, A., Bélier, B., Bennett, D., Bergé, L., Bernard, J. Ph., Bersanelli, M., Bigot-Sazy, M. A., Bleurvacq, N., Bordier, G., Brossard, J., Bunn, E. F., Burke, D. P., Buzi, D., Buzzelli, A., Cammilleri, D., Cavaliere, F., Chanial, P., Chapron, C., Columbro, F., Coppi, G., Coppolecchia, A., Couchot, F., D'Agostino, R., D'Alessandro, G., de Bernardis, P., De Gasperis, G., De Leo, M., De Petris, M., Decourcelle, T., Del Torto, F., Dumoulin, L., Etchegoyen, A., Franceschet, C., Garcia, B., Gault, A., Gayer, D., Gervasi, M., Ghribi, A., Giard, M., Giraud-Héraud, Y., Gradziel, M., Grandsire, L., Hamilton, J. Ch., Harari, D., Haynes, V., Henrot-Versillé, S., Holtzer, N., Incardona, F., Kaplan, J., Korotkov, A., Krachmalnicoff, N., Lamagna, L., Lande, J., Loucatos, S., Lowitz, A., Lukovic, V., Maffei, B., Marnieros, S., Martino, J., Masi, S., May, A., McCulloch, M., Medina, M. C., Mele, L., Melhuish, S., Montier, L., Murphy, A., Néel, D., Ng, M. W., O'Sullivan, C., Paiella, A., Pajot, F., Passerini, A., Pelosi, A., Perbost, C., Perdereau, O., Piacentini, F., Piat, M., Piccirillo, L., Pisano, G., Préle, D., Puddu, R., Rambaud, D., Rigaut, O., Romero, G. E., Salatino, M., Schillaci, A., Scully, S., Stolpovskiy, M., Suarez, F., Tartari, A., Timbie, P., Torchinsky, S., Tristram, M., Tucker, C., Tucker, G., Viganò, D., Vittorio, N., Voisin, F., Watson, B., Zannoni, M., and Zullo, A.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

In this paper we describe QUBIC, an experiment that takes up the challenge posed by the detection of primordial gravitational waves with a novel approach, that combines the sensitivity of state-of-the art bolometric detectors with the systematic effects control typical of interferometers. The so-called "self-calibration" is a technique deeply rooted in the interferometric nature of the instrument and allows us to clean the measured data from instrumental effects. The first module of QUBIC is a dual band instrument (150 GHz and 220 GHz) that will be deployed in Argentina during the Fall 2018., Comment: Presented at the EPS Conference on High Energy Physics, Venice (Italy), 5-12 July 2017 Accepted for publication in conference proceedings

Published
2018

8. QUBIC Technical Design Report

Author

Aumont, J., Banfi, S., Battaglia, P., Battistelli, E. S., Baù, A., Bélier, B., Bennett, D., Bergé, L., Bernard, J. Ph., Bersanelli, M., Bigot-Sazy, M. A., Bleurvacq, N., Bordier, G., Brossard, J., Bunn, E. F., Buzi, D., Buzzelli, A., Cammilleri, D., Cavaliere, F., Chanial, P., Chapron, C., Coppi, G., Coppolecchia, A., Couchot, F., D'Agostino, R., D'Alessandro, G., de Bernardis, P., De Gasperis, G., De Petris, M., Decourcelle, T., Del Torto, F., Dumoulin, L., Etchegoyen, A., Franceschet, C., Garcia, B., Gault, A., Gayer, D., Gervasi, M., Ghribi, A., Giard, M., Giraud-Héraud, Y., Gradziel, M., Grandsire, L., Hamilton, J. Ch., Harari, D., Haynes, V., Henrot-Versillé, S., Holtzer, N., Kaplan, J., Korotkov, A., Lamagna, L., Lande, J., Loucatos, S., Lowitz, A., Lukovic, V., Maffei, B., Marnieros, S., Martino, J., Masi, S., May, A., McCulloch, M., Medina, M. C., Melhuish, S., Mennella, A., Montier, L., Murphy, A., Néel, D., Ng, M. W., O'Sullivan, C., Paiella, A., Pajot, F., Passerini, A., Pelosi, A., Perbost, C., Perdereau, O., Piacentini, F., Piat, M., Piccirillo, L., Pisano, G., Prêle, D., Puddu, R., Rambaud, D., Rigaut, O., Romero, G. E., Salatino, M., Schillaci, A., Scully, S., Stolpovskiy, M., Suarez, F., Tartari, A., Timbie, P., Tristram, M., Tucker, G., Viganò, D., Vittori, N., Voisin, F., Watson, B., Zannoni, M., and Zullo, A.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

QUBIC is an instrument aiming at measuring the B mode polarisation anisotropies at medium scales angular scales (30-200 multipoles). The search for the primordial CMB B-mode polarization signal is challenging, because of many difficulties: smallness of the expected signal, instrumental systematics that could possibly induce polarization leakage from the large E signal into B, brighter than anticipated polarized foregrounds (dust) reducing to zero the initial hope of finding sky regions clean enough to have a direct primordial B-modes observation. The QUBIC instrument is designed to address all aspects of this challenge with a novel kind of instrument, a Bolometric Interferometer, combining the background-limited sensitivity of Transition-Edge-Sensors and the control of systematics allowed by the observation of interference fringe patterns, while operating at two frequencies to disentangle polarized foregrounds from primordial B mode polarization. Its characteristics are described in details in this Technological Design Report., Comment: 139 pages ; high resolution version can be found on the qubic website (http://qubic.in2p3.fr/QUBIC/Home.html) minor changes : update author list & affiliations ; correct title

Published
2016

11. The Large-Scale Polarization Explorer (LSPE)

Author

The LSPE collaboration, Aiola, S., Amico, G., Battaglia, P., Battistelli, E., Baù, A., de Bernardis, P., Bersanelli, M., Boscaleri, A., Cavaliere, F., Coppolecchia, A., Cruciani, A., Cuttaia, F., Addabbo, A. D', D'Alessandro, G., De Gregori, S., Del Torto, F., De Petris, M., Fiorineschi, L., Franceschet, C., Franceschi, E., Gervasi, M., Goldie, D., Gregorio, A., Haynes, V., Krachmalnicoff, N., Lamagna, L., Maffei, B., Maino, D., Masi, S., Mennella, A., Wah, Ng Ming, Morgante, G., Nati, F., Pagano, L., Passerini, A., Peverini, O., Piacentini, F., Piccirillo, L., Pisano, G., Ricciardi, S., Rissone, P., Romeo, G., Salatino, M., Sandri, M., Schillaci, A., Stringhetti, L., Tartari, A., Tascone, R., Terenzi, L., Tomasi, M., Tommasi, E., Villa, F., Virone, G., Withington, S., Zacchei, A., and Zannoni, M.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - Cosmology and Extragalactic Astrophysics
Abstract

The LSPE is a balloon-borne mission aimed at measuring the polarization of the Cosmic Microwave Background (CMB) at large angular scales, and in particular to constrain the curl component of CMB polarization (B-modes) produced by tensor perturbations generated during cosmic inflation, in the very early universe. Its primary target is to improve the limit on the ratio of tensor to scalar perturbations amplitudes down to r = 0.03, at 99.7% confidence. A second target is to produce wide maps of foreground polarization generated in our Galaxy by synchrotron emission and interstellar dust emission. These will be important to map Galactic magnetic fields and to study the properties of ionized gas and of diffuse interstellar dust in our Galaxy. The mission is optimized for large angular scales, with coarse angular resolution (around 1.5 degrees FWHM), and wide sky coverage (25% of the sky). The payload will fly in a circumpolar long duration balloon mission during the polar night. Using the Earth as a giant solar shield, the instrument will spin in azimuth, observing a large fraction of the northern sky. The payload will host two instruments. An array of coherent polarimeters using cryogenic HEMT amplifiers will survey the sky at 43 and 90 GHz. An array of bolometric polarimeters, using large throughput multi-mode bolometers and rotating Half Wave Plates (HWP), will survey the same sky region in three bands at 95, 145 and 245 GHz. The wide frequency coverage will allow optimal control of the polarized foregrounds, with comparable angular resolution at all frequencies., Comment: In press. Copyright 2012 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited

Published
2012

12. A coherent polarimeter array for the Large Scale Polarization Explorer balloon experiment

Author

Bersanelli, M., Mennella, A., Morgante, G., Zannoni, M., Addamo, G., Baschirotto, A., Battaglia, P., Baù, A., Cappellini, B., Cavaliere, F., Cuttaia, F., Del Torto, F., Donzelli, S., Farooqui, Z., Frailis, M., Franceschet, C., Franceschi, E., Gaier, T., Galeotta, S., Gervasi, M., Gregorio, A., Kangaslahti, P., Krachmalnicoff, N., Lawrence, C., Maggio, G., Mainini, R., Maino, D., Mandolesi, N., Paroli, B., Passerini, A., Peverini, O. A., Poli, S., Ricciardi, S., Rossetti, M., Sandri, M., Seiffert, M., Stringhetti, L., Tartari, A., Tascone, R., Tavagnacco, D., Terenzi, L., Tomasi, M., Tommasi, E., Villa, F., Virone, G., and Zacchei, A.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

We discuss the design and expected performance of STRIP (STRatospheric Italian Polarimeter), an array of coherent receivers designed to fly on board the LSPE (Large Scale Polarization Explorer) balloon experiment. The STRIP focal plane array comprises 49 elements in Q band and 7 elements in W-band using cryogenic HEMT low noise amplifiers and high performance waveguide components. In operation, the array will be cooled to 20 K and placed in the focal plane of a $\sim 0.6$ meter telescope providing an angular resolution of $\sim1.5$ degrees. The LSPE experiment aims at large scale, high sensitivity measurements of CMB polarization, with multi-frequency deep measurements to optimize component separation. The STRIP Q-band channel is crucial to accurately measure and remove the synchrotron polarized component, while the W-band channel, together with a bolometric channel at the same frequency, provides a crucial cross-check for systematic effects., Comment: In press on the Proceedings of the SPIE Conference Astronomical Telescopes + instrumentation 2012, Amsterdam, paper 8446-279

Published
2012
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13. Peripheral Blood Mononuclear Cells (PB-MNCs) for the treatment of chronic tissue dystrophy in a complex case of lower limb reconstruction.

Author

CARELLA, S., PATANÈ, L., CASTRECHINI, M., TORTO, F. LO, MARRUZZO, G., REDI, U., GRECO, M., RIBUFFO, D., and ONESTI, M. G.

Abstract

BACKGROUND: Recently, the infiltration of a subpopulation of cells represented by mononucleated cells extracted from peripheral blood [Peripheral Blood-Mononuclear Cells (PB-MNCs)] is becoming a useful technique for medical and surgical regenerative procedures. Due to the angiogenetic and regenerative properties of PB-MNCs, the infiltration of these cells is, in our opinion, a new option indicated in the treatment of pathologies characterized by tissue dystrophy, loss of vascularization, and non-healing wounds. CASE PRESENTATION: A 25-year-old active smoker patient was diagnosed with Rhabdomyosarcoma of the anterior tibial muscle of his left leg and treated with neoadjuvant chemo- and radiotherapy (RT). After the tumor excision, the patient developed wound dehiscence with bone exposure and a perilesional radiation-induced chronic dermatitis characterized by skin dyschromia and hair thinning along the treated area. The patient underwent surgical debridement and reconstruction with autologous skin grafts and dermal substitutes, with poor outcomes due to graft failure. The patient was subsequently treated with surgical debridement and coverage with a reverse sural fascia-cutaneous flap. After 13 days, wound dehiscence was observed, and reconstruction of the dehiscent areas was performed with a split-thickness autologous skin graft with no success. After wound debridement, a new split-thickness skin graft was performed, and a concentrate of autologous PB-MNCs was injected in the flap and perilesional skin. After 14 days, graft take was reached, and improvements in perilesional tissue tropism were noted. At 2 months follow-up, the patient appeared completely healed. CONCLUSIONS: In our opinion, the use of PB-MNCs to treat conditions characterized by tissue dystrophy, which require neoangiogenesis and cell regeneration, can be a useful and unconsidered technique that could be utilized to improve tissue tropism. Furthermore, prospective trials are necessary to validate our observations. [ABSTRACT FROM AUTHOR]

Published
2024

16. The LSPE-Strip feed horn array

Author

Franceschet, C, Del Torto, F, Villa, F, Realini, S, Bongiolatti, R, Peverini, O, Pezzotta, F, Viganó, D, Addamo, G, Bersanelli, M, Cavaliere, F, Cuttaia, F, Gervasi, M, Mennella, A, Morgante, G, Taylor, A, Virone, G, Zannoni, M, Franceschet, C., Del Torto, F., Villa, F., Realini, S., Bongiolatti, R., Peverini, O. A., Pezzotta, F., Viganó, D. M., Addamo, G., Bersanelli, M., Cavaliere, F., Cuttaia, F., Gervasi, M., Mennella, A., Morgante, G., Taylor, A. C., Virone, G., Zannoni, M., Franceschet, C, Del Torto, F, Villa, F, Realini, S, Bongiolatti, R, Peverini, O, Pezzotta, F, Viganó, D, Addamo, G, Bersanelli, M, Cavaliere, F, Cuttaia, F, Gervasi, M, Mennella, A, Morgante, G, Taylor, A, Virone, G, Zannoni, M, Franceschet, C., Del Torto, F., Villa, F., Realini, S., Bongiolatti, R., Peverini, O. A., Pezzotta, F., Viganó, D. M., Addamo, G., Bersanelli, M., Cavaliere, F., Cuttaia, F., Gervasi, M., Mennella, A., Morgante, G., Taylor, A. C., Virone, G., and Zannoni, M.

Abstract

In this paper we discuss the design, manufacturing and characterization of the feed horn array of the Strip instrument of the Large Scale Polarization Explorer (LSPE) experiment. Strip is a microwave telescope, operating in the Q-and W-band, for the observation of the polarized emissions from the sky in a large fraction (about 37%) of the Northern hemisphere with sub-degree angular resolution. The Strip focal plane is populated by forty-nine Q-band and six W-band corrugated horns, each feeding a cryogenically cooled polarimeter for the detection of the Stokes Q and U components of the polarized signal from the sky. The Q-band channel is designed to accurately monitor Galactic polarized synchrotron emission, while the combination of Q-and W-band will allow the study of atmospheric effects at the observation site, the Observatorio del Teide, in Tenerife. In this paper we focus on the development of the Strip corrugated feed horns, including design requirements, engineering and manufacturing, as well as detailed characterization and performance verification.

Published
2022

17. Restructuring surgical training after COVID-19 pandemic: A nationwide survey on the Italian scenario on behalf of the Italian polyspecialistic young surgeons society (SPIGC)

Author

Gaetano, G., Guaitoli, E., Barra, F., Picciariello, A., Pasculli, A., Coppola, A., Pertile, D., Meniconi, R. L., Berton, F., Conti, L., Formisano, G., Iossa, A., Maruccia, M., Mazzari, Mario Attilio, Oragano, L., Ratti, F., Serenari, M., Settembrini, A., Sirignano, P., Soriero, D., Vallicelli, C., Vizzielli, Giuseppe, Dimonte, R., Cianci, Stefano, Giovenzana, M., Palmieri, G., Pasqui, E., Petrillo, Marco, Portigliotti, L., Sambucci, D., Sena, G., Sparavigna, M., Bettini, G., Fanello, G., Mendogni, P., Monteleone, L., Ardo, N. P., Tomaiuolo, P., Tomasicchio, G., Paradiso, N., Dibra, R., Trigiante, G., Dezi, A., Carbone, Luigi, Negrello, S., Di Bartolomeo, M., Patini, Romeo, Marcuzzo, A. V., Campione, A., Comacchio, G., Murana, G., Antonio, M., Manitto, M., Galzerano, G., Di Marco, Carmine, Velluti, F., Berardi, Giulia, Romboli, A., Perelli, F., Weindelmejer, J., Tamburrino, D., Calarco, Alessandro, Losco, L., Nacchiero, E., Elia, R., Torto, F. L., Vicenti, G., Pappalardo, V., Pisani, D., Palmisano, Gerardo, Brascia, D., Troisi, L., Renzi, F., Melandro, F., Pecere, Silvia, Gazia, C., Di Franco, G., Romano, G., Bolletta, A., Botteri, E., Di Meo, G., Chiappetta, S., Sgaramella, I., Pennestri, F., Girardi, A., Mariniello, D., Marcasciano, M., Telegrafo, M., Fracomeni, S., De Paoli, F., Mazzari A. (ORCID:0000-0002-7301-6834), Vizzielli G., Cianci S., Petrillo M., Carbone L., Patini R. (ORCID:0000-0001-7358-8763), Di Marco C., Berardi G., Calarco A., Palmisano G., Pecere S., Gaetano, G., Guaitoli, E., Barra, F., Picciariello, A., Pasculli, A., Coppola, A., Pertile, D., Meniconi, R. L., Berton, F., Conti, L., Formisano, G., Iossa, A., Maruccia, M., Mazzari, Mario Attilio, Oragano, L., Ratti, F., Serenari, M., Settembrini, A., Sirignano, P., Soriero, D., Vallicelli, C., Vizzielli, Giuseppe, Dimonte, R., Cianci, Stefano, Giovenzana, M., Palmieri, G., Pasqui, E., Petrillo, Marco, Portigliotti, L., Sambucci, D., Sena, G., Sparavigna, M., Bettini, G., Fanello, G., Mendogni, P., Monteleone, L., Ardo, N. P., Tomaiuolo, P., Tomasicchio, G., Paradiso, N., Dibra, R., Trigiante, G., Dezi, A., Carbone, Luigi, Negrello, S., Di Bartolomeo, M., Patini, Romeo, Marcuzzo, A. V., Campione, A., Comacchio, G., Murana, G., Antonio, M., Manitto, M., Galzerano, G., Di Marco, Carmine, Velluti, F., Berardi, Giulia, Romboli, A., Perelli, F., Weindelmejer, J., Tamburrino, D., Calarco, Alessandro, Losco, L., Nacchiero, E., Elia, R., Torto, F. L., Vicenti, G., Pappalardo, V., Pisani, D., Palmisano, Gerardo, Brascia, D., Troisi, L., Renzi, F., Melandro, F., Pecere, Silvia, Gazia, C., Di Franco, G., Romano, G., Bolletta, A., Botteri, E., Di Meo, G., Chiappetta, S., Sgaramella, I., Pennestri, F., Girardi, A., Mariniello, D., Marcasciano, M., Telegrafo, M., Fracomeni, S., De Paoli, F., Mazzari A. (ORCID:0000-0002-7301-6834), Vizzielli G., Cianci S., Petrillo M., Carbone L., Patini R. (ORCID:0000-0001-7358-8763), Di Marco C., Berardi G., Calarco A., Palmisano G., and Pecere S.

Abstract

Introduction: The COVID-19 pandemic has led to the disruption of surgical training. Lack of communication, guidelines for managing clinical activity as well as concerns for safety in the workplace appeared to be relevant issues. This study aims to investigate how surgical training has been reorganized in Italy, almost 2 years after the outbreak of COVID-19 pandemic. Materials and methods: A 16-item-electronic anonymous questionnaire was designed through SurveyMonkey© web application. This survey was composed of different sections concerning demographic characteristics and impacts of the second COVID-19 pandemic wave on surgical and research/didactic activities. Changes applied in the training programme and activities carried out were also investigated. The survey was carried out in the period between June and October 2021. Results: Four hundred and thirty responses were collected, and 399 were considered eligible to be included in the study analysis. Three hundred and thirty-five respondents continued working in Surgical Units, with a significant reduction (less than one surgical session per week) of surgical sessions in 49.6% of them. With concern to didactic and research activities, 140 residents maintained their usual activity, while 116 reported a reduction. A sub-group analysis on resident moved to COVID-19 departments showed a reduction of research activities in 35% of them. During the period considered in this survey, the surgical training program was not substantially modified for most of participants (74.6%). Conclusion: Our survey demonstrated that surgical residency programs haven't improved 2 years after the beginning of the pandemic. Further improvements are needed to guarantee completeness of surgical training, even in emergency conditions.

Published
2023

19. The role of component separation in the treatment of severe diastasis recti abdominis: a new indication for a known technique.

Author

REDI, U., KACIULYTE, J., MARINO, D., NANNI, J., LO TORTO, F., MARCASCIANO, M., RIBUFFO, D., ALFANO, C., and MAZZOCCHI, M.

Abstract

OBJECTIVE: Diastasis of the rectus abdominis muscle (DRAM) is a widening of linea alba, it also could be accompanied by abdominal bulging. DRAM is often a cause of quality-of-life impairment, especially when it is of large dimensions. Repair with direct rectus plication is the most common treatment for Diastasis Recti Abdominis (DRA), but it can result in high recurrence rates. The authors aimed to show their results in applying the component separation technique in wide DRA cases. PATIENTS AND METHODS: From January 2015 to July 2018, 43 patients with DRA = 10 cm at 3 cm over the umbilicus have been treated with component separation technique associated to panniculectomy. A biologic mesh was positioned onlay in cases of weakness along the semilunaris lines. RESULTS: DRA repair was achieved in all cases. All patients completed the 1-year follow-up and no recurrence nor major complication were registered. Minor complications were observed in 12 (27.9%) cases. CONCLUSIONS: This is the first study describing the component separation technique use in cases of DRA without hernia, associated to abdominoplasty surgery. Preliminary results were encouraging, but larger series are required. [ABSTRACT FROM AUTHOR]

Published
2023

21. QUBIC: A Fizeau Interferometer Targeting Primordial B-Modes

Author

Tartari, A., Aumont, J., Banfi, S., Battaglia, P., Battistelli, E. S., Baù, A., Bélier, B., Bennett, D., Bergé, L., Bernard, J. Ph., Bersanelli, M., Bigot-Sazy, M. A., Bleurvacq, N., Bordier, G., Brossard, J., Bunn, E. F., Buzi, D., Cammilleri, D., Cavaliere, F., Chanial, P., Chapron, C., Coppolecchia, A., D’Alessandro, G., De Bernardis, P., Decourcelle, T., Del Torto, F., De Petris, M., Dumoulin, L., Franceschet, C., Gault, A., Gayer, D., Gervasi, M., Ghribi, A., Giard, M., Giraud-Héraud, Y., Gradziel, M., Grandsire, L., Hamilton, J. Ch., Haynes, V., Holtzer, N., Kaplan, J., Korotkov, A., Lande, J., Lowitz, A., Maffei, B., Marnieros, S., Martino, J., Masi, S., McCulloch, M., Melhuish, S., Mennella, A., Montier, L., Murphy, A., Néel, D., Ng, M. W., O’Sullivan, C., Pajot, F., Passerini, A., Perbost, C., Piacentini, F., Piat, M., Piccirillo, L., Pisano, G., Prêle, D., Rambaud, D., Rigaut, O., Salatino, M., Schillaci, A., Scully, S., Stolpovskiy, M. M., Timbie, P., Tucker, G., Viganò, D., Voisin, F., Watson, B., and Zannoni, M.

Published
2016
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22. Progress Report on the Large-Scale Polarization Explorer

Author

Lamagna, L, Addamo, G, Ade, P, Baccigalupi, C, Baldini, A, Battaglia, P, Battistelli, E, Baù, A, Bersanelli, M, Biasotti, M, Boragno, C, Boscaleri, A, Caccianiga, B, Caprioli, S, Cavaliere, F, Cei, F, Cleary, K, Columbro, F, Coppi, G, Coppolecchia, A, Corsini, D, Cuttaia, F, D’Alessandro, G, de Bernardis, P, De Gasperis, G, De Petris, M, Torto, F, Fafone, V, Farooqui, Z, Farsian, F, Fontanelli, F, Franceschet, C, Gaier, T, Gatti, F, Genova-Santos, R, Gervasi, M, Ghigna, T, Grassi, M, Grosso, D, Incardona, F, Jones, M, Kangaslahti, P, Krachmalnicoff, N, Mainini, R, Maino, D, Mandelli, S, Maris, M, Masi, S, Matarrese, S, May, A, Mena, P, Mennella, A, Molina, R, Molinari, D, Morgante, G, Nati, F, Natoli, P, Pagano, L, Paiella, A, Paonessa, F, Passerini, A, Perez-de-Taoro, M, Peverini, O, Pezzotta, F, Piacentini, F, Piccirillo, L, Pisano, G, Polastri, L, Polenta, G, Poletti, D, Presta, G, Realini, S, Reyes, N, Rocchi, A, Rubino-Martin, J, Sandri, M, Sartor, S, Schillaci, A, Signorelli, G, Soria, M, Spinella, F, Tapia, V, Tartari, A, Taylor, A, Terenzi, L, Tomasi, M, Tommasi, E, Tucker, C, Vaccaro, D, Vigano, D, Villa, F, Virone, G, Vittorio, N, Volpe, A, Watkins, B, Zacchei, A, Zannoni, M, Lamagna, L., Addamo, G., Ade, P. A. R., Baccigalupi, C., Baldini, A. M., Battaglia, P. M., Battistelli, E., Baù, A., Bersanelli, M., Biasotti, M., Boragno, C., Boscaleri, A., Caccianiga, B., Caprioli, S., Cavaliere, F., Cei, F., Cleary, K. A., Columbro, F., Coppi, G., Coppolecchia, A., Corsini, D., Cuttaia, F., D’Alessandro, G., de Bernardis, P., De Gasperis, G., De Petris, M., Torto, F. Del, Fafone, V., Farooqui, Z., Farsian, F., Fontanelli, F., Franceschet, C., Gaier, T. C., Gatti, F., Genova-Santos, R., Gervasi, M., Ghigna, T., Grassi, M., Grosso, D., Incardona, F., Jones, M., Kangaslahti, P., Krachmalnicoff, N., Mainini, R., Maino, D., Mandelli, S., Maris, M., Masi, S., Matarrese, S., May, A., Mena, P., Mennella, A., Molina, R., Molinari, D., Morgante, G., Nati, F., Natoli, P., Pagano, L., Paiella, A., Paonessa, F., Passerini, A., Perez-de-Taoro, M., Peverini, O. A., Pezzotta, F., Piacentini, F., Piccirillo, L., Pisano, G., Polastri, L., Polenta, G., Poletti, D., Presta, G., Realini, S., Reyes, N., Rocchi, A., Rubino-Martin, J. A., Sandri, M., Sartor, S., Schillaci, A., Signorelli, G., Soria, M., Spinella, F., Tapia, V., Tartari, A., Taylor, A., Terenzi, L., Tomasi, M., Tommasi, E., Tucker, C., Vaccaro, D., Vigano, D. M., Villa, F., Virone, G., Vittorio, N., Volpe, A., Watkins, B., Zacchei, A., Zannoni, M., Lamagna, L, Addamo, G, Ade, P, Baccigalupi, C, Baldini, A, Battaglia, P, Battistelli, E, Baù, A, Bersanelli, M, Biasotti, M, Boragno, C, Boscaleri, A, Caccianiga, B, Caprioli, S, Cavaliere, F, Cei, F, Cleary, K, Columbro, F, Coppi, G, Coppolecchia, A, Corsini, D, Cuttaia, F, D’Alessandro, G, de Bernardis, P, De Gasperis, G, De Petris, M, Torto, F, Fafone, V, Farooqui, Z, Farsian, F, Fontanelli, F, Franceschet, C, Gaier, T, Gatti, F, Genova-Santos, R, Gervasi, M, Ghigna, T, Grassi, M, Grosso, D, Incardona, F, Jones, M, Kangaslahti, P, Krachmalnicoff, N, Mainini, R, Maino, D, Mandelli, S, Maris, M, Masi, S, Matarrese, S, May, A, Mena, P, Mennella, A, Molina, R, Molinari, D, Morgante, G, Nati, F, Natoli, P, Pagano, L, Paiella, A, Paonessa, F, Passerini, A, Perez-de-Taoro, M, Peverini, O, Pezzotta, F, Piacentini, F, Piccirillo, L, Pisano, G, Polastri, L, Polenta, G, Poletti, D, Presta, G, Realini, S, Reyes, N, Rocchi, A, Rubino-Martin, J, Sandri, M, Sartor, S, Schillaci, A, Signorelli, G, Soria, M, Spinella, F, Tapia, V, Tartari, A, Taylor, A, Terenzi, L, Tomasi, M, Tommasi, E, Tucker, C, Vaccaro, D, Vigano, D, Villa, F, Virone, G, Vittorio, N, Volpe, A, Watkins, B, Zacchei, A, Zannoni, M, Lamagna, L., Addamo, G., Ade, P. A. R., Baccigalupi, C., Baldini, A. M., Battaglia, P. M., Battistelli, E., Baù, A., Bersanelli, M., Biasotti, M., Boragno, C., Boscaleri, A., Caccianiga, B., Caprioli, S., Cavaliere, F., Cei, F., Cleary, K. A., Columbro, F., Coppi, G., Coppolecchia, A., Corsini, D., Cuttaia, F., D’Alessandro, G., de Bernardis, P., De Gasperis, G., De Petris, M., Torto, F. Del, Fafone, V., Farooqui, Z., Farsian, F., Fontanelli, F., Franceschet, C., Gaier, T. C., Gatti, F., Genova-Santos, R., Gervasi, M., Ghigna, T., Grassi, M., Grosso, D., Incardona, F., Jones, M., Kangaslahti, P., Krachmalnicoff, N., Mainini, R., Maino, D., Mandelli, S., Maris, M., Masi, S., Matarrese, S., May, A., Mena, P., Mennella, A., Molina, R., Molinari, D., Morgante, G., Nati, F., Natoli, P., Pagano, L., Paiella, A., Paonessa, F., Passerini, A., Perez-de-Taoro, M., Peverini, O. A., Pezzotta, F., Piacentini, F., Piccirillo, L., Pisano, G., Polastri, L., Polenta, G., Poletti, D., Presta, G., Realini, S., Reyes, N., Rocchi, A., Rubino-Martin, J. A., Sandri, M., Sartor, S., Schillaci, A., Signorelli, G., Soria, M., Spinella, F., Tapia, V., Tartari, A., Taylor, A., Terenzi, L., Tomasi, M., Tommasi, E., Tucker, C., Vaccaro, D., Vigano, D. M., Villa, F., Virone, G., Vittorio, N., Volpe, A., Watkins, B., Zacchei, A., and Zannoni, M.

Abstract

The large-scale polarization explorer (LSPE) is a cosmology program for the measurement of large-scale curl-like features (B-modes) in the polarization of the cosmic microwave background. Its goal is to constrain the background of inflationary gravity waves traveling through the universe at the time of matter-radiation decoupling. The two instruments of LSPE are meant to synergically operate by covering a large portion of the northern microwave sky. LSPE/STRIP is a coherent array of receivers planned to be operated from the Teide Observatory in Tenerife, for the control and characterization of the low-frequency polarized signals of galactic origin; LSPE/SWIPE is a balloon-borne bolometric polarimeter based on 330 large throughput multi-moded detectors, designed to measure the CMB polarization at 150 GHz and to monitor the polarized emission by galactic dust above 200 GHz. The combined performance and the expected level of systematics mitigation will allow LSPE to constrain primordial B-modes down to a tensor/scalar ratio of 10^−2. We here report the status of the STRIP pre-commissioning phase and the progress in the characterization of the key subsystems of the SWIPE payload (namely the cryogenic polarization modulation unit and the multi-moded TES pixels) prior to receiver integration.

Published
2020

23. The LSPE-Strip feed horn array

Author

Franceschet, C., primary, Del Torto, F., additional, Villa, F., additional, Realini, S., additional, Bongiolatti, R., additional, Peverini, O.A., additional, Pezzotta, F., additional, Viganó, D.M., additional, Addamo, G., additional, Bersanelli, M., additional, Cavaliere, F., additional, Cuttaia, F., additional, Gervasi, M., additional, Mennella, A., additional, Morgante, G., additional, Taylor, A.C., additional, Virone, G., additional, and Zannoni, M., additional

Published
2022
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24. Pyoderma Gangrenosum and inflammatory bowel disease: a combined medical and surgical approach - case report and literature review.

Author

GARIERI, P., MARCASCIANO, M., CIRIACO, A. GRETO, SPAGNUOLO, R., VITAGLIANO, T., KACIULYTE, J., CASELLA, D., LO TORTO, F., PARISI, P., RIBUFFO, D., and GRECO, M.

Abstract

OBJECTIVE: Pyoderma Gangrenosum (PG) is an immune-mediated neutrophilic dermatosis, characterized by large painful ulcers occurring in various body segments. It can be associated to Inflammatory Bowel Disease (IBD) including both Ulcerative Colitis and Crohn Disease. Prompt and effective management is fundamental, due to its high morbidity and mortality rates. By presenting our clinical experience, we aimed at showing the efficacy of a combined therapeutic approach, in which the best of every specialty cooperates managing this hazardous disease. PATIENTS AND METHODS: We report on two patients attending our outpatient clinic with ulcerative skin lesions at the level of the back. Patient 1 suffered from Crohn disease and Patient 2 presented a positive history of abdominal pain, diarrhea with mucus and blood in the stool. Histological exam was performed with final diagnosis of PG associated with IBD. A Literature review was carried out in order to highlight the role of combined clinical-surgical management of PG in adult patients with IBD. RESULTS: Complete resolution of the lesions was achieved in 4 months and 3 months for each patient respectively without relapse. PubMed was searched from 2000 to 2020 with the following keywords: (Pyoderma) AND/OR (Pyoderma Gangrenosum) AND (Inflammatory Bowel Disease) AND/OR (Ulcerative Colitis) AND/OR (Crohn Disease) AND (Management). Seven papers were included (4 case reports, 2 case series, 1 comprehensive review) and reviewed using a descriptive checklist. CONCLUSIONS: PG should be treated by dedicated multidisciplinary teams, in which every specialist plays a crucial role from the diagnosis to the treatment and up to the long-term follow-up. [ABSTRACT FROM AUTHOR]

Published
2022

25. Breast surgeons updating on the thresholds of COVID-19 era: results of a multicenter collaborative study evaluating the role of online videos and multimedia sources on breast surgeons education and training

Author

Marcasciano, M., Kaciulyte, J., Mori, F. L. R., Torto, F. L., Barellini, L., Loreti, A., Fanelli, B., Vita, R. D., Redi, U., Marcasciano, F., Cesare, F. D., Pra, G. D., Conversi, A., Elia, L., Montemari, G., Vaia, N., Bernini, M., Sordi, S., Luridiana, G., D'Ermo, G., Monti, M., Luca, A. D., Ricci, F., Mazzocchi, M., Gentilucci, M., Greco, M., Losco, L., Valdatta, L. A., Raposio, E., Giudice, G., Maruccia, M., Benedetto, G. D., Cigna, E., Casella, D., and Ribuffo, D.

Subjects
Breast surgery, Online videos, Social media, Surgical training, Betacoronavirus, Breast Neoplasms, COVID-19, Coronavirus Infections, Education, Distance, Female, Humans, Mastectomy, Pandemics, Pneumonia, Viral, Quality of Life, SARS-CoV-2, Social Media, Surgeons, Surveys and Questionnaires, Video Recording, Pneumonia, Viral, Education, Distance
Abstract

Current trends show a rise of attention given to breast cancer patients' quality of life and the surgical reconstructive result. Along with this trend, surgical training quality and efficacy are gaining importance and innovative training methods such as online videos shared on social media portals, are becoming main updating tools. In hazardous times like COVID-19 pandemic nowadays, online communication becomes of vital importance and adaptation and innovation are fundamental to keep research and education alive. The authors aimed to investigate the role of video and multimedia sources on the daily activity and surgical training of a representative group of surgeons specifically dedicated to oncologic, oncoplastic and reconstructive breast surgeries.A survey was produced and administered to 20 major Italian Breast Centers. Collected data were analyzed with Fisher's Exact Test.From October 2019 to March 2020, a total of 320 surveys were collected. Among the responders, there were 188 trainees (intern medical doctors and residents) and 110 faculty, 72% of them belonged to a plastic surgery environment, while 28% to general surgery environment. Almost all respondents have ever watched videos concerning breast surgery.The results of the study show how breast surgeons rely on videos and web platforms, mostly YouTube, when searching for training info about surgical procedures. Social media offer great opportunities for sharing knowledge and diffusion of new ideas but greater attention to their reliability is mandatory.

Published
2020

27. Progress Report on the Large-Scale Polarization Explorer

Author

Lamagna, L., primary, Addamo, G., additional, Ade, P. A. R., additional, Baccigalupi, C., additional, Baldini, A. M., additional, Battaglia, P. M., additional, Battistelli, E., additional, Baù, A., additional, Bersanelli, M., additional, Biasotti, M., additional, Boragno, C., additional, Boscaleri, A., additional, Caccianiga, B., additional, Caprioli, S., additional, Cavaliere, F., additional, Cei, F., additional, Cleary, K. A., additional, Columbro, F., additional, Coppi, G., additional, Coppolecchia, A., additional, Corsini, D., additional, Cuttaia, F., additional, D’Alessandro, G., additional, de Bernardis, P., additional, De Gasperis, G., additional, De Petris, M., additional, Torto, F. Del, additional, Fafone, V., additional, Farooqui, Z., additional, Farsian, F., additional, Fontanelli, F., additional, Franceschet, C., additional, Gaier, T. C., additional, Gatti, F., additional, Genova-Santos, R., additional, Gervasi, M., additional, Ghigna, T., additional, Grassi, M., additional, Grosso, D., additional, Incardona, F., additional, Jones, M., additional, Kangaslahti, P., additional, Krachmalnicoff, N., additional, Mainini, R., additional, Maino, D., additional, Mandelli, S., additional, Maris, M., additional, Masi, S., additional, Matarrese, S., additional, May, A., additional, Mena, P., additional, Mennella, A., additional, Molina, R., additional, Molinari, D., additional, Morgante, G., additional, Nati, F., additional, Natoli, P., additional, Pagano, L., additional, Paiella, A., additional, Paonessa, F., additional, Passerini, A., additional, Perez-de-Taoro, M., additional, Peverini, O. A., additional, Pezzotta, F., additional, Piacentini, F., additional, Piccirillo, L., additional, Pisano, G., additional, Polastri, L., additional, Polenta, G., additional, Poletti, D., additional, Presta, G., additional, Realini, S., additional, Reyes, N., additional, Rocchi, A., additional, Rubino-Martin, J. A., additional, Sandri, M., additional, Sartor, S., additional, Schillaci, A., additional, Signorelli, G., additional, Soria, M., additional, Spinella, F., additional, Tapia, V., additional, Tartari, A., additional, Taylor, A., additional, Terenzi, L., additional, Tomasi, M., additional, Tommasi, E., additional, Tucker, C., additional, Vaccaro, D., additional, Vigano, D. M., additional, Villa, F., additional, Virone, G., additional, Vittorio, N., additional, Volpe, A., additional, Watkins, B., additional, Zacchei, A., additional, and Zannoni, M., additional

Published
2020
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28. Postsurgical antithrombotic therapy in microsurgery: Our protocol and literature review

Author

Kaciulyte, J., Losco, L., Maruccia, M., Delia, G., Lo Torto, F., Di Taranto, G., Caputo, G. G., Berchiolli, R., Ribuffo, D., and Cigna, E.

Subjects
Postoperative Care, Anticoagulation, Antithrombotic, Free flap, Microsurgery, Postoperative therapy, Postoperative Complications, Fibrinolytic Agents, Humans, microsurgery, postoperative therapy, anticoagulation, antithrombotic, free flap
Abstract

Despite the improvements reached by microsurgeons in the last 30 years, postoperative complications still occur and most of them are the result of venous thrombosis at the pedicle anastomosis. Primary prevention of thrombosis is mandatory and anticoagulant therapy in the preoperative and postoperative period is widely used. Still, there is a lack of consensus in the literature about the best postoperative protocol for microsurgical reconstruction. The authors aimed to review the postoperative antithrombotic regimens described in literature focusing on their effects and risks, and moreover, share their experience.The authors performed a literature review of postsurgical antithrombotic protocols applied in reconstructive microsurgery. Research on PubMed server was performed typing the terms "antithrombotic", "postoperative", "microsurgery", "free flap pedicle", "anticlotting", "anticoagulant".The authors described the postoperative standardized pro-weight pharmacological protocol applied in their unit: a combination of dextran and heparin. They inhibit more than one pattern of coagulation in order to stop platelet aggregation and thrombin action and, in the meantime, contending fluid loss with plasma expansion.Nowadays, a non-standardized practice, based on experience, is applied by microsurgeons in postsurgical care; the authors performed a review of the combined antithrombotic therapies described in the literature. A standardized pro-weight pharmacological protocol is proposed; it allows to increase blood flow by volume expander action (Dextran) and thrombin inhibition (Heparin). Still, coagulation cascade and platelet function have a wide variability among humans, as well as the effect of drugs. Achieving an optimal antithrombotic effect and minimizing adverse reactions meantime remains a challenge.

Published
2019

29. Venous thromboembolism prophylaxis in plastic surgery: state of the art and our approach.

Author

REDI, U., MARRUZZO, G., CODOLINI, L., CHISTOLINI, A., TARALLO, M., MARCASCIANO, M., LO TORTO, F., GRIPPAUDO, F. R., CASELLA, D., and RIBUFFO, D.

Abstract

OBJECTIVE: The issue of prevention of thromboembolism in plastic surgery is a rather controversial subject. The actual frequency of VTE among plastic surgery patients is probably higher than we know. Although several studies have shown that chemoprophylaxis likely increases rates of re-operative hematoma by less than one percent, surgeons are strongly resistant to adopting chemoprophylaxis due to the fear of increased bleeding and its complications. MATERIALS AND METHODS: A literature review was conducted. The 2012 ACCP guidelines suggest the use of the 2005 Caprini score as the most widely used and well-validated individualized risk-stratification tool. We propose a modified 2005 Caprini score, with specific changes pertaining to plastic surgery, in which we combine a patient risk stratification model and a procedure-driven approach explicitly indicating what procedures have to be considered at high or low risk. RESULTS: The risk of venous thromboembolism in plastic surgery cannot be disregarded. However, the plastic surgery literature still lacks high-level evidence for appropriate means of VTE prophylaxis, although an increasing amount of attention has been paid to the topic. We suggest the development of an international guideline, based on plastic surgical data, using a validated risk assessment model, which combines the surgical risk with the patient related risk. CONCLUSIONS: Determining the proper venous thromboembolism prophylaxis is a clinical decision that should be made on a patient-to-patient basis. The algorithm presented in this article is meant to simplify this complex problem and to help expedite and clarify the decision-making process. [ABSTRACT FROM AUTHOR]

Published
2021

30. Oncological safety of stromal vascular fraction enriched fat grafting in two-stage breast reconstruction after nipple sparing mastectomy: long-term results of a prospective study

Author

Calabrese, C., Kothari, A., Badylak, S., Di Taranto, G., Marcasciano, M., Sordi, S., Barellini, L., Lo Torto, F., Tarallo, M., Gaggelli, I., D'Ermo, G., Fausto, A., Casella, D., and Ribuffo, D.

Subjects
Adult, Mammaplasty, Breast Neoplasms, Middle Aged, Transplantation, Autologous, stromal vascular fraction, Cohort Studies, oncological safety, breast cancer, pharmacology (medical), Adipose Tissue, Humans, Female, Adipose derived stem cells, Prospective Studies, enriched fat grafting, fat grafting, SVF, Organ Sparing Treatments, Mastectomy
Abstract

Autologous fat transfer (AFT) is commonly used to treat implant palpability and prevent fibrosis and thinning in mastectomy skin flaps. A major limit to this procedure is volume retention over time, leading to the introduction of fat enrichment with stromal vascular fraction (SVF+AFT). Oncological concerns have been raised over the injection of an increased concentration of progenitors cells (ASCs) in the SVF. The aim of the study is to evaluate the long-term cancer recurrence risk of SVF+AFT cases compared to AFT, in patients undergoing Nipple Sparing Mastectomy (NSM).A prospective study was designed to compare three groups of patients undergoing NSM followed by SVF+AFT, AFT or none (control group), after a two-stage breast reconstruction. Patients were strictly followed-up for at least 5-years from the second stage reconstructive procedure. Loco-regional and systemic recurrence rate were evaluated over time as the primary outcome. Logistic regression was used to investigate which factors were associated with recurrence events and independent variables of interest were: surgical technique, age above 50 years old, lympho-vascular invasion, oncological stage, adjuvant or neoadjuvant chemotherapy, adjuvant radiotherapy and adjuvant hormone therapy.41 women were included in G1 (SVF+AFT), 64 in G2 (AFT), and 64 in G3 (control group). Loco-regional recurrence rate was 2.4% for G1, 4.7% for G2, and 1.6% for G3. Systemic recurrence was 7.3%, 3.1%, and 3.1%, respectively. Among the variables included, there were no significant risk factors influencing a recurrence event, either loco-regional or systemic. In particular, SVF+AFT (G1) did not increase the oncological recurrence.Our data suggest that both centrifuged and SVF-enhanced fat transfer have a similar safety level in comparison to patients who did not undergo fat grafting in breast reconstruction after NSM.

Published
2018

31. QUBIC: the Q&U Bolometric Interferometer for Cosmology. A novel way to look at the polarized Cosmic Microwave Background.

Author

Mennella, Aniello, Ade, P.A.R., Aumont, J., Banfi, S., Battaglia, P., Battistelli, E., Bau, A., Bélier, B., Bennett, D., Bergé, L., Bernard, J.-P., Bersanelli, M., Bigot-Sazy, M.-A., Bleurvacq, N., Bordier, G., Brossard, J., Bunn, Emory F., Burke, D.P., Buzi, D., Buzzelli, A., Cammilleri, D., Cavaliere, F., Chanial, P., Chapron, C., Columbro, F., Coppi, G., Coppolecchia, A., Couchot, F., D'Agostino, R., D'Alessandro, Giuseppe, De Bernardis, P., de Gasperis, G., De Leo, M., De Petris, M., Decourcelle, T., Del Torto, F., Dumoulin, L., Etchegoyen, A., Franceschet, C., Garcia, B., Gault, Amanda, Gayer, D., Gervasi, M., Ghribi, A., Giard, M., Giraud-Héraud, Y., Gradziel, Marcin, Grandsire, L., Hamilton, J.-Ch., Harari, D., Haynes, V., Henrot-Versille, S., Holtzer, N., Incardona, F., Kaplan, J., Korotkov, A., Krachmalnicoff, N., Lamagna, L., Landé, J., Loucatos, S., Lowitz, A., Lukovic, V., Maffei, B., Marnieros, S., Martino, J., Masi, S., May, A., McCulloch, M., Medina, M.C., Mele, L., Melhuish, Simon, Montier, L., Murphy, A., Néel, D., Ng, M.W., O'Sullivan, C., Paiella, A., Pajot, F., Passerini, A., Pelosi, A., Perbost, C., Perdereau, O., Piacentini, F., Piat, M., Piccirillo, Lucio, Pisano, G., Prêle, D., Puddu, R., Rambaud, D., Rigaut, O., Romero, G.E., Salatino, M., Schillaci, A., Scully, Stephen, Stolpovskiy, M., Suarez, F., Tartari, A., Timbie, P., Torchinsky, S., Tristram, M., Tucker, C., Tucker, G., Viganò, D., Vittorio, N., Voisin, F., Watson, B., Zannoni, M., Mennella, Aniello, Ade, P.A.R., Aumont, J., Banfi, S., Battaglia, P., Battistelli, E., Bau, A., Bélier, B., Bennett, D., Bergé, L., Bernard, J.-P., Bersanelli, M., Bigot-Sazy, M.-A., Bleurvacq, N., Bordier, G., Brossard, J., Bunn, Emory F., Burke, D.P., Buzi, D., Buzzelli, A., Cammilleri, D., Cavaliere, F., Chanial, P., Chapron, C., Columbro, F., Coppi, G., Coppolecchia, A., Couchot, F., D'Agostino, R., D'Alessandro, Giuseppe, De Bernardis, P., de Gasperis, G., De Leo, M., De Petris, M., Decourcelle, T., Del Torto, F., Dumoulin, L., Etchegoyen, A., Franceschet, C., Garcia, B., Gault, Amanda, Gayer, D., Gervasi, M., Ghribi, A., Giard, M., Giraud-Héraud, Y., Gradziel, Marcin, Grandsire, L., Hamilton, J.-Ch., Harari, D., Haynes, V., Henrot-Versille, S., Holtzer, N., Incardona, F., Kaplan, J., Korotkov, A., Krachmalnicoff, N., Lamagna, L., Landé, J., Loucatos, S., Lowitz, A., Lukovic, V., Maffei, B., Marnieros, S., Martino, J., Masi, S., May, A., McCulloch, M., Medina, M.C., Mele, L., Melhuish, Simon, Montier, L., Murphy, A., Néel, D., Ng, M.W., O'Sullivan, C., Paiella, A., Pajot, F., Passerini, A., Pelosi, A., Perbost, C., Perdereau, O., Piacentini, F., Piat, M., Piccirillo, Lucio, Pisano, G., Prêle, D., Puddu, R., Rambaud, D., Rigaut, O., Romero, G.E., Salatino, M., Schillaci, A., Scully, Stephen, Stolpovskiy, M., Suarez, F., Tartari, A., Timbie, P., Torchinsky, S., Tristram, M., Tucker, C., Tucker, G., Viganò, D., Vittorio, N., Voisin, F., Watson, B., and Zannoni, M.

Abstract

In this paper we describe QUBIC, an experiment that takes up the challenge posed by the detection of primordial gravitational waves with a novel approach, that combines the sensitivity of state-of-the art bolometric detectors with the systematic effects control typical of interferometers. The so-called 'self-calibration' is a technique deeply rooted in the interferometric nature of the instrument and allows us to clean the measured data from instrumental effects. The first module of QUBIC is a dual band instrument (150 GHz and 220 GHz) that will be deployed in Argentina during Fall 2018.

Published
2018

32. The STRIP instrument of the Large Scale Polarization Explorer: microwave eyes to map the Galactic polarized foregrounds

Author

Iovenitti, S, Zannoni, M, Zacchei, A, Watkins, B, Volpe, A, Virone, G, Villa, F, Vigano', D, Tommasi, E, Tomasi, M, Terenzi, L, Tapia, V, Soria, M, Sartor, S, Sandri, M, Rubino-Martin, J, Rocchi, A, Reyes, N, Realini, S, Pincella, C, Pezzotta, F, Peverini, O, Perez-de-Taoro, M, Passerini, A, Morgante, G, Molina, R, Mennella, A, Mena, P, Maris, M, Maino, D, Mainini, R, Kangaslahti, P, Jones, M, Incardona, F, Ghigna, T, Gervasi, M, Gaier, T, Genova Santos, R, Farooqui, Z, Fafone, V, Del Torto, F, Cuttaia, F, Cleary, K, Cavaliere, F, Caprioli, S, Caccianiga, B, Bersanelli, M, Battaglia, P, Bau', A, Addamo, G, Franceschet, C, Iovenitti, Simone, Zannoni, Mario, Zacchei, Andrea, Watkins, Bob, Volpe, Angela, Virone, Giuseppe, Villa, Fabrizio, Vigano', Daniele M., Tommasi, Elisabetta, Tomasi, Maurizio, Terenzi, Luca, Tapia, Valeria, Soria, Mary, Sartor, Stefano, Sandri, Maura, Rubino-Martin, Jose' A., Rocchi, Alessio, Reyes, Nicolas, Realini, Sabrina, Pincella, Claudio, Pezzotta, Federico, Peverini, Oscar A., Perez-de-Taoro, Maria del Rosario, Passerini, Andrea, Morgante, Gianluca, Molina, Rocio, Mennella, Aniello, Mena, Patricio, Maris, Michele, Maino, Davide, Mainini, Roberto, Kangaslahti, Pekka, Jones, Mike, Incardona, Federico, Ghigna, Tommaso, Gervasi, Massimo, Gaier, Todd C., Genova Santos, Ricardo T., Farooqui, Zunnoorain, Fafone, Viviana, Del Torto, Francesco, Cuttaia, Francesco, Cleary, Kieran A., Cavaliere, Francesco, Caprioli, Silvia, Caccianiga, Barbara, Bersanelli, Marco, Battaglia, Paola M., Bau', Alessandro, Addamo, Giuseppe, Franceschet, Cristian, Iovenitti, S, Zannoni, M, Zacchei, A, Watkins, B, Volpe, A, Virone, G, Villa, F, Vigano', D, Tommasi, E, Tomasi, M, Terenzi, L, Tapia, V, Soria, M, Sartor, S, Sandri, M, Rubino-Martin, J, Rocchi, A, Reyes, N, Realini, S, Pincella, C, Pezzotta, F, Peverini, O, Perez-de-Taoro, M, Passerini, A, Morgante, G, Molina, R, Mennella, A, Mena, P, Maris, M, Maino, D, Mainini, R, Kangaslahti, P, Jones, M, Incardona, F, Ghigna, T, Gervasi, M, Gaier, T, Genova Santos, R, Farooqui, Z, Fafone, V, Del Torto, F, Cuttaia, F, Cleary, K, Cavaliere, F, Caprioli, S, Caccianiga, B, Bersanelli, M, Battaglia, P, Bau', A, Addamo, G, Franceschet, C, Iovenitti, Simone, Zannoni, Mario, Zacchei, Andrea, Watkins, Bob, Volpe, Angela, Virone, Giuseppe, Villa, Fabrizio, Vigano', Daniele M., Tommasi, Elisabetta, Tomasi, Maurizio, Terenzi, Luca, Tapia, Valeria, Soria, Mary, Sartor, Stefano, Sandri, Maura, Rubino-Martin, Jose' A., Rocchi, Alessio, Reyes, Nicolas, Realini, Sabrina, Pincella, Claudio, Pezzotta, Federico, Peverini, Oscar A., Perez-de-Taoro, Maria del Rosario, Passerini, Andrea, Morgante, Gianluca, Molina, Rocio, Mennella, Aniello, Mena, Patricio, Maris, Michele, Maino, Davide, Mainini, Roberto, Kangaslahti, Pekka, Jones, Mike, Incardona, Federico, Ghigna, Tommaso, Gervasi, Massimo, Gaier, Todd C., Genova Santos, Ricardo T., Farooqui, Zunnoorain, Fafone, Viviana, Del Torto, Francesco, Cuttaia, Francesco, Cleary, Kieran A., Cavaliere, Francesco, Caprioli, Silvia, Caccianiga, Barbara, Bersanelli, Marco, Battaglia, Paola M., Bau', Alessandro, Addamo, Giuseppe, and Franceschet, Cristian

Abstract

In this paper we discuss the latest developments of the STRIP instrument of the “Large Scale Polarization Explorer” (LSPE) experiment. LSPE is a novel project that combines ground-based (STRIP) and balloon-borne (SWIPE) polarization measurements of the microwave sky on large angular scales to attempt a detection of the “B-modes” of the Cosmic Microwave Background polarization. STRIP will observe approximately 25% of the Northern sky from the “Observatorio del Teide” in Tenerife, using an array of forty-nine coherent polarimeters at 43 GHz, coupled to a 1.5 m fully rotating crossed-Dragone telescope. A second frequency channel with six-elements at 95 GHz will be exploited as an atmospheric monitor. At present, most of the hardware of the STRIP instrument has been developed and tested at sub-system level. System-level characterization, starting in July 2018, will lead STRIP to be shipped and installed at the observation site within the end of the year. The on-site verification and calibration of the whole instrument will prepare STRIP for a 2-years campaign for the observation of the CMB polarization.

Published
2018

33. QUBIC: the Q&U Bolometric Interferometer for Cosmology. A novel way to look at the polarized Cosmic Microwave Background

Author

Mennella, A, Ade, P, Aumont, J, Banfi, S, Incardona, F, Battaglia, P, Battistelli, E, Baù, A, Bélier, B, Bennett, D, Bergé, L, Bernard, J, Bersanelli, M, Bigot-Sazy, M, Bleurvacq, N, Bordier, G, Brossard, J, Bunn, E, Burke, D, Buzi, D, Buzzelli, A, Cammilleri, D, Cavaliere, F, Chanial, P, Chapron, C, Columbro, F, Coppi, G, Coppolecchia, A, Couchot, F, D'Agostino, R, D'Alessandro, G, De Bernardis, P, De Gasperis, G, De Leo, M, De Petris, M, Decourcelle, T, Del Torto, F, Dumoulin, L, Etchegoyen, A, Franceschet, C, Garcia, B, Gault, A, Gayer, D, Gervasi, M, Ghribi, A, Giard, M, Giraud-Héraud, Y, Gradziel, M, Grandsire, L, Hamilton, J, Harari, D, Haynes, V, Henrot-Versillé, S, Holtzer, N, Kaplan, J, Korotkov, A, Krachmalnicoff, N, Lamagna, L, Lande, J, Loucatos, S, Lowitz, A, Lukovic, V, Maffei, B, Marnieros, S, Martino, J, Masi, S, May, A, Mcculloch, M, Medina, M, Mele, L, Melhuish, S, Montier, L, Murphy, A, Néel, D, Ng, M, O'Sullivan, C, Paiella, A, Pajot, F, Passerini, A, Pelosi, A, Perbost, C, Perdereau, O, Piacentini, F, Piat, M, Piccirillo, L, Pisano, G, Prêle, D, Puddu, R, Rambaud, D, Rigaut, O, Romero, G, Salatino, M, Schillaci, A, Scully, S, Stolpovskiy, M, Suarez, F, Tartari, A, Timbie, P, Torchinsky, S, Tristram, M, Tucker, C, Tucker, G, Viganò, D, Vittori, N, Voisin, F, Watson, B, Zannoni, M, Zullo, A, Zullo, A., Mennella, A, Ade, P, Aumont, J, Banfi, S, Incardona, F, Battaglia, P, Battistelli, E, Baù, A, Bélier, B, Bennett, D, Bergé, L, Bernard, J, Bersanelli, M, Bigot-Sazy, M, Bleurvacq, N, Bordier, G, Brossard, J, Bunn, E, Burke, D, Buzi, D, Buzzelli, A, Cammilleri, D, Cavaliere, F, Chanial, P, Chapron, C, Columbro, F, Coppi, G, Coppolecchia, A, Couchot, F, D'Agostino, R, D'Alessandro, G, De Bernardis, P, De Gasperis, G, De Leo, M, De Petris, M, Decourcelle, T, Del Torto, F, Dumoulin, L, Etchegoyen, A, Franceschet, C, Garcia, B, Gault, A, Gayer, D, Gervasi, M, Ghribi, A, Giard, M, Giraud-Héraud, Y, Gradziel, M, Grandsire, L, Hamilton, J, Harari, D, Haynes, V, Henrot-Versillé, S, Holtzer, N, Kaplan, J, Korotkov, A, Krachmalnicoff, N, Lamagna, L, Lande, J, Loucatos, S, Lowitz, A, Lukovic, V, Maffei, B, Marnieros, S, Martino, J, Masi, S, May, A, Mcculloch, M, Medina, M, Mele, L, Melhuish, S, Montier, L, Murphy, A, Néel, D, Ng, M, O'Sullivan, C, Paiella, A, Pajot, F, Passerini, A, Pelosi, A, Perbost, C, Perdereau, O, Piacentini, F, Piat, M, Piccirillo, L, Pisano, G, Prêle, D, Puddu, R, Rambaud, D, Rigaut, O, Romero, G, Salatino, M, Schillaci, A, Scully, S, Stolpovskiy, M, Suarez, F, Tartari, A, Timbie, P, Torchinsky, S, Tristram, M, Tucker, C, Tucker, G, Viganò, D, Vittori, N, Voisin, F, Watson, B, Zannoni, M, Zullo, A, and Zullo, A.

Abstract

In this paper we describe QUBIC, an experiment that takes up the challenge posed by the detection of primordial gravitational waves with a novel approach, that combines the sensitivity of state-of-the art bolometric detectors with the systematic effects control typical of interferometers. The so-called ``self-calibration'' is a technique deeply rooted in the interferometric nature of the instrument and allows us to clean the measured data from instrumental effects. The first module of QUBIC is a dual band instrument (150 GHz and 220 GHz) that will be deployed in Argentina during Fall 2018

Published
2018

34. Prepectoral breast reconstruction with TiLoop® Bra Pocket: a single center prospective study.

Author

TORTO, F. LO, MARCASCIANO, M., KACIULYTE, J., REDI, U., BARELLINI, L., DE LUCA, A., PERRA, A., FRATTAROLI, J. M., CAVALIERI, E., DI TARANTO, G., GRECO, M., and CASELLA, D.

Abstract

OBJECTIVE: In the last decades, immediate breast reconstruction (IBR) raised in frequency, and prepectoral positioning of the implant is becoming the trend nowadays. The aim of this paper is to describe our case series in IBR with prepectoral implant placement and complete coverage of it with the TiLoop® Bra titanium-coated polypropylene mesh (TCPM), pre-shaped as a pocket. PATIENTS AND METHODS: Eighteen women with breast tumors were selected and underwent mono- or bilateral mastectomies and prepectoral IBR with tissue expanders or prostheses. After the prepectoral lodge was ready, the implants were inserted into TiLoop® Bra Pocket meshes and positioned over the pectoralis major muscle fascia. The mean surgical time of their positioning was four minutes. RESULTS: This preliminary study showed meaningful results in prepectoral IBR with Ti- Loop® Bra Pocket covering the implants, for we observed a reduction of implant's exposure time and risk of bacterial contamination. Of the 18 patients that underwent this procedure, only three presented complications that resolved in a maximum of four weeks. CONCLUSIONS: A considering reduction of surgical time in implant positioning was achieved, lowering exposure time and risk of complications as infection. [ABSTRACT FROM AUTHOR]

Published
2020

35. QUBIC: the Q&U Bolometric Interferometer for Cosmology. A novel way to look at the polarized Cosmic Microwave Background.

Author

Mennella, Aniello, primary, R. Ade, P. A., additional, Aumont, J., additional, Banfi, S., additional, Incardona, F., additional, Battaglia, P., additional, Battistelli, E.S., additional, Baù, A., additional, Bélier, B., additional, Bennett, D., additional, Bergé, L., additional, Bernard, J.Ph., additional, Bersanelli, M., additional, Bigot-Sazy, M.A., additional, Bleurvacq, N., additional, Bordier, G., additional, Brossard, J., additional, Bunn, E.F., additional, P. Burke, D., additional, Buzi, D., additional, Buzzelli, A., additional, Cammilleri, D., additional, Cavaliere, F., additional, Chanial, P., additional, Chapron, C., additional, Columbro, Fabio, additional, Coppi, G., additional, Coppolecchia, A., additional, Couchot, F., additional, D'Agostino, R., additional, D'Alessandro, G., additional, De Bernardis, P., additional, De Gasperis, G., additional, De Leo, Michele, additional, De Petris, M., additional, Decourcelle, T., additional, Del Torto, F., additional, Dumoulin, L., additional, Etchegoyen, A., additional, Franceschet, C., additional, Garcia, B., additional, Gault, A., additional, Gayer, D., additional, Gervasi, M., additional, Ghribi, A., additional, Giard, M., additional, Giraud-Héraud, Y., additional, Gradziel, M., additional, Grandsire, L., additional, Hamilton, J.Ch., additional, Harari, D., additional, Haynes, V., additional, Henrot-Versillé, S., additional, Holtzer, N., additional, Kaplan, J., additional, Korotkov, A., additional, Krachmalnicoff, N., additional, Lamagna, L., additional, Lande, J., additional, Loucatos, S., additional, Lowitz, A., additional, Lukovic, V., additional, Maffei, B., additional, Marnieros, S., additional, Martino, J. Rodriguez, additional, Masi, S., additional, May, A., additional, McCulloch, M., additional, Medina, M.C., additional, Mele, Lorenzo, additional, Melhuish, S., additional, Montier, L., additional, Murphy, A., additional, Néel, D., additional, Ng, M.W., additional, O'Sullivan, C., additional, Paiella, A., additional, Pajot, F., additional, Passerini, A., additional, Pelosi, A., additional, Perbost, C., additional, Perdereau, O., additional, Piacentini, F., additional, Piat, M., additional, Piccirillo, L., additional, Pisano, G., additional, Prêle, D., additional, Puddu, R., additional, Rambaud, D., additional, Rigaut, O., additional, Romero, G.E., additional, Salatino, M., additional, Schillaci, A., additional, Scully, S., additional, Stolpovskiy, M., additional, Suarez, F., additional, Tartari, A., additional, Timbie, P., additional, Torchinsky, Steve A., additional, Tristram, M., additional, Tucker, C., additional, Tucker, G., additional, Viganò, D., additional, Vittori, N., additional, Voisin, F., additional, Watson, B., additional, Zannoni, M., additional, and Zullo, A., additional

Published
2017
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37. Management of microanastomosis in patients affected by vessel diseases

Author

Cigna, E., Lo Torto, F., PAOLA PARISI, Felli, A., and Ribuffo, D.

Subjects
Microsurgery, Microanastomosis, Arteriovenous Anastomosis, Atherosclerosis, Humans, Monckeberg Medial Calcific Sclerosis, Surgical Flaps, Disease Management, Microanastomosis, microsurgery, aterosclerosis, radiotherapy
Abstract

In the last 10 years with the advances in microsurgery of techniques and materials the indications for free tissue transfer have considerably been increased. But, there are still some limitations and drawbacks. Among risk factors associated with flap failure, atherosclerosis can affect both the flap and the recipient vessels of free microvascular tissue transfers. The purpose of this paper is to discuss about the pathogenesis of Monckeberg's sclerosis, and the topics that must be taken into consideration when performing microsurgery in these patients.PubMed database was searched using Mesh. The following terms was added to the search builder: Monckeberg's sclerosis, free flap. The Boolean operator "AND" was selected. All the selectable Mesh headings for "Monckeberg's sclerosis" and "free flap" were included.Almost all the literature works about microsurgery in Monckeberg's sclerosis patient show the importance of an accurate preoperative and postoperative evaluation and of a proper surgical technique.When adequate preoperative evaluation, surgical technique and postoperative monitoring are performed, even severe atherosclerosis should not be considered an absolute contraindication for microvascular surgery.

Published
2014

38. Optical design and modelling of the QUBIC instrument, a next-generation quasi-optical bolometric interferometer for cosmology

Author

Holland, WS, Scully, S, Burke, D, O'Sullivan, C, Gayer, D, Gradziel, M, Murphy, J, De Petris, M, Buzi, D, Zannoni, M, Mennella, A, Gervasi, M, Tartari, A, Maffei, B, Aumont, J, Banfi, S, Battaglia, P, Battistelli, E, Bau', A, Bélier, B, Bennet, D, Bergé, L, Bernard, J, Bersanelli, M, Bigot Sazy, M, Bleurvacq, N, Bordier, G, Brossard, J, Bunn, E, Cammileri, D, Cavaliere, F, Chanial, P, Chapron, C, Coppolecchia, A, Couchot, F, D'Alessandro, G, De Bernardis, P, Decourcelle, T, Del Torto, F, Dumoulin, L, Franceschet, C, Gault, A, Ghribi, A, Giard, M, Giraud Héraud, Y, Grandsire, L, Hamilton, J, Haynes, V, Henrot Versillé, S, Holtzer, N, Kaplan, J, Korotkov, A, Lande, J, Lowitz, A, Marnieros, S, Martino, J, Masi, S, Mcculloch, M, Melhuish, S, Montier, L, Néel, D, Ng, M, Pajot, F, Passerini, A, Perbost, C, Perdereau, O, Piacentini, F, Piat, M, Piccirillo, L, Pisano, G, Prêle, D, Puddu, R, Rambaud, D, Rigaut, O, Salatino, M, Schillaci, A, Stolpovskiy, M, Timbie, P, Tristram, M, Tucker, G, Viganò, D, Voisin, F, Watson, B, Watson, B., ZANNONI, MARIO, GERVASI, MASSIMO, BANFI, STEFANO, BAU', ALESSANDRO, PASSERINI, ANDREA, Holland, WS, Scully, S, Burke, D, O'Sullivan, C, Gayer, D, Gradziel, M, Murphy, J, De Petris, M, Buzi, D, Zannoni, M, Mennella, A, Gervasi, M, Tartari, A, Maffei, B, Aumont, J, Banfi, S, Battaglia, P, Battistelli, E, Bau', A, Bélier, B, Bennet, D, Bergé, L, Bernard, J, Bersanelli, M, Bigot Sazy, M, Bleurvacq, N, Bordier, G, Brossard, J, Bunn, E, Cammileri, D, Cavaliere, F, Chanial, P, Chapron, C, Coppolecchia, A, Couchot, F, D'Alessandro, G, De Bernardis, P, Decourcelle, T, Del Torto, F, Dumoulin, L, Franceschet, C, Gault, A, Ghribi, A, Giard, M, Giraud Héraud, Y, Grandsire, L, Hamilton, J, Haynes, V, Henrot Versillé, S, Holtzer, N, Kaplan, J, Korotkov, A, Lande, J, Lowitz, A, Marnieros, S, Martino, J, Masi, S, Mcculloch, M, Melhuish, S, Montier, L, Néel, D, Ng, M, Pajot, F, Passerini, A, Perbost, C, Perdereau, O, Piacentini, F, Piat, M, Piccirillo, L, Pisano, G, Prêle, D, Puddu, R, Rambaud, D, Rigaut, O, Salatino, M, Schillaci, A, Stolpovskiy, M, Timbie, P, Tristram, M, Tucker, G, Viganò, D, Voisin, F, Watson, B, Watson, B., ZANNONI, MARIO, GERVASI, MASSIMO, BANFI, STEFANO, BAU', ALESSANDRO, and PASSERINI, ANDREA

Abstract

Big Bang cosmologies predict that the cosmic microwave background (CMB) contains faint temperature and polarisation anisotropies imprinted in the early universe. ESA's PLANCK satellite has already measured the temperature anisotropies1 in exquisite detail; the next ambitious step is to map the primordial polarisation signatures which are several orders of magnitude lower. Polarisation E-modes have been measured2 but the even-fainter primordial B-modes have so far eluded detection. Their magnitude is unknown but it is clear that a sensitive telescope with exceptional control over systematic errors will be required. QUBIC3 is a ground-based European experiment that aims to exploit the novel concept of bolometric interferometry in order to measure B-mode polarisation anisotropies in the CMB. Beams from an aperture array of corrugated horns will be combined to form a synthesised image of the sky Stokes parameters on two focal planes: one at 150 GHz the other at 220 GHz. In this paper we describe recent optical modelling of the QUBIC beam combiner, concentrating on modelling the instrument point-spread-function and its operation in the 220-GHz band. We show the effects of optical aberrations and truncation as successive components are added to the beam path. In the case of QUBIC, the aberrations introduced by off-axis mirrors are the dominant contributor. As the frequency of operation is increased, the aperture horns allow up to five hybrid modes to propagate and we illustrate how the beam pattern changes across the 25% bandwidth. Finally we describe modifications to the QUBIC optical design to be used in a technical demonstrator, currently being manufactured for testing in 2016.

Published
2016

39. QUBIC: A Fizeau Interferometer Targeting Primordial B-Modes

Author

Tartari, A, Aumont, J, Banfi, S, Battaglia, P, Battistelli, E, Bau', A, Bélier, B, Bennett, D, Bergé, L, Bernard, J, Bersanelli, M, Bigot Sazy, M, Bleurvacq, N, Bordier, G, Brossard, J, Bunn, E, Buzi, D, Cammilleri, D, Cavaliere, F, Chanial, P, Chapron, C, Coppolecchia, A, D’Alessandro, G, De Bernardis, P, Decourcelle, T, Del Torto, F, De Petris, M, Dumoulin, L, Franceschet, C, Gault, A, Gayer, D, Gervasi, M, Ghribi, A, Giard, M, Giraud Héraud, Y, Gradziel, M, Grandsire, L, Hamilton, J, Haynes, V, Holtzer, N, Kaplan, J, Korotkov, A, Lande, J, Lowitz, A, Maffei, B, Marnieros, S, Martino, J, Masi, S, Mcculloch, M, Melhuish, S, Mennella, A, Montier, L, Murphy, A, Néel, D, Ng, M, O’Sullivan, C, Pajot, F, Passerini, A, Perbost, C, Piacentini, F, Piat, M, Piccirillo, L, Pisano, G, Prêle, D, Rambaud, D, Rigaut, O, Salatino, M, Schillaci, A, Scully, S, Stolpovskiy, M, Timbie, P, Tucker, G, Viganò, D, Voisin, F, Watson, B, Zannoni, M, BANFI, STEFANO, BAU', ALESSANDRO, GERVASI, MASSIMO, PASSERINI, ANDREA, ZANNONI, MARIO, Tartari, A, Aumont, J, Banfi, S, Battaglia, P, Battistelli, E, Bau', A, Bélier, B, Bennett, D, Bergé, L, Bernard, J, Bersanelli, M, Bigot Sazy, M, Bleurvacq, N, Bordier, G, Brossard, J, Bunn, E, Buzi, D, Cammilleri, D, Cavaliere, F, Chanial, P, Chapron, C, Coppolecchia, A, D’Alessandro, G, De Bernardis, P, Decourcelle, T, Del Torto, F, De Petris, M, Dumoulin, L, Franceschet, C, Gault, A, Gayer, D, Gervasi, M, Ghribi, A, Giard, M, Giraud Héraud, Y, Gradziel, M, Grandsire, L, Hamilton, J, Haynes, V, Holtzer, N, Kaplan, J, Korotkov, A, Lande, J, Lowitz, A, Maffei, B, Marnieros, S, Martino, J, Masi, S, Mcculloch, M, Melhuish, S, Mennella, A, Montier, L, Murphy, A, Néel, D, Ng, M, O’Sullivan, C, Pajot, F, Passerini, A, Perbost, C, Piacentini, F, Piat, M, Piccirillo, L, Pisano, G, Prêle, D, Rambaud, D, Rigaut, O, Salatino, M, Schillaci, A, Scully, S, Stolpovskiy, M, Timbie, P, Tucker, G, Viganò, D, Voisin, F, Watson, B, Zannoni, M, BANFI, STEFANO, BAU', ALESSANDRO, GERVASI, MASSIMO, PASSERINI, ANDREA, and ZANNONI, MARIO

Abstract

Q and U Bolometric Interferometer for Cosmology (QUBIC) is a Fizeau interferometer sensitive to linear polarisation, to be deployed at the Antarctic station of Dome C. This experiment in its final configuration will be operated at 97, 150 and 220 GHz and is intended to target CMB primordial B-modes in a multipole window 20 < l< 150. A sensitivity of r= 0.05 (95 % CL) can be reached by the first module alone, after 2 years of operation. Here we review in particular its working principles, and we show how the QUBIC interferometric configuration can be considered equivalent to a pupil-plane filtered imaging system. In this context, we show how our instrument can be self-calibrated. Finally, we conclude by showing an overview of the first dual-band module (150/220 GHz), which will serve also as a demonstrator for the subsequent units, and review the technological choices we made for each subsystem, with particular emphasis on the detection system.

Published
2016

40. Free Flap Revascularisation Process

Author

Cigna, Emanuele, Lo Torto, F., Napoli, A., Vesely, J., and Ribuffo, Diego

Subjects
Angio CT, ultrasound, Imaging, Plastic Surgery, Angio CT, radiology, flap surgery, ultrasound, flap surgery, radiology
Published
2014

42. Optical design and modelling of the QUBIC instrument, a next-generation quasi-optical bolometric interferometer for cosmology

Author

Scully, S., additional, Burke, D., additional, O'Sullivan, C., additional, Gayer, D., additional, Gradziel, M., additional, Murphy, J. A., additional, De Petris, M., additional, Buzi, D., additional, Zannoni, M., additional, Mennella, A, additional, Gervasi, M., additional, Tartari, A., additional, Maffei, B., additional, Aumont, J., additional, Banfi, S., additional, Battaglia, P., additional, Battistelli, E. S., additional, Baù, A., additional, Bélier, B., additional, Bennet, D., additional, Bergé, L., additional, Bernard, J.-Ph., additional, Bersanelli, M., additional, Bigot-Sazy, M.-A., additional, Bleurvacq, N., additional, Bordier, G., additional, Brossard, J., additional, Bunn, E. F., additional, Cammileri, D., additional, Cavaliere, F., additional, Chanial, P., additional, Chapron, C., additional, Coppolecchia, A., additional, Couchot, F., additional, D'Alessandro, G., additional, De Bernardis, P., additional, Decourcelle, T., additional, Del Torto, F., additional, Dumoulin, L., additional, Franceschet, C., additional, Gault, A., additional, Ghribi, A., additional, Giard, M., additional, Giraud-Héraud, Y., additional, Grandsire, L., additional, Hamilton, J. C., additional, Haynes, V., additional, Henrot-Versillé, S., additional, Holtzer, N., additional, Kaplan, J., additional, Korotkov, A., additional, Lande, J., additional, Lowitz, A., additional, Marnieros, S., additional, Martino, J., additional, Masi, S., additional, McCulloch, Mark, additional, Melhuish, Simon, additional, Montier, L., additional, Néel, D., additional, Ng, M. W., additional, Pajot, F., additional, Passerini, A., additional, Perbost, C., additional, Perdereau, O., additional, Piacentini, F., additional, Piat, M., additional, Piccirillo, L., additional, Pisano, G., additional, Prêle, D., additional, Puddu, R., additional, Rambaud, D., additional, Rigaut, O., additional, Salatino, M., additional, Schillaci, A., additional, Stolpovskiy, M., additional, Timbie, P., additional, Tristram, M., additional, Tucker, G., additional, Viganò, D., additional, Voisin, F., additional, and Watson, B., additional

Published
2016
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43. Q-band antenna-feed system for the Large Scale Polarization Explorer balloon experiment

Author

Peverini, O, Virone, G, Del Torto, F, Franceschet, C, Villa, F, Lumia, M, Farooqui, Z, Mennella, A, Bersanelli, M, Zannoni, M, Gervasi, M, Addamo, G, Battaglia, P, Cavaliere, F, Morgante, G, Gregorio, A, Zacchei, A, Tascone, R, Tascone, R., ZANNONI, MARIO, GERVASI, MASSIMO, Peverini, O, Virone, G, Del Torto, F, Franceschet, C, Villa, F, Lumia, M, Farooqui, Z, Mennella, A, Bersanelli, M, Zannoni, M, Gervasi, M, Addamo, G, Battaglia, P, Cavaliere, F, Morgante, G, Gregorio, A, Zacchei, A, Tascone, R, Tascone, R., ZANNONI, MARIO, and GERVASI, MASSIMO

Abstract

This work will present the corrugated-horns, polarizers and ortho-mode transducers developed for the 49-element coherent polarimeter array working in [39, 48] GHz to be embarked in the Large Scale Polarization Explorer. The latter is an ASI-funded balloon experiment designed to measure the CMB B-modes on large angular scales. The presentation will focus on the analysis, design, manufacturing and measurements of these components.

Published
2015

44. A 7X7 Elements Q-Band Feed-Horn Array for the LSPE-Strip Experiment

Author

Del Torto, F, Franceschet, C, Villa, F, Battaglia, P, Bersanelli, M, Cavaliere, F, Gervasi, M, Gregorio, A, Mennella, A, Morgante, G, Peverini, O, Pezzotta, F, Zacchei, A, Zannoni, M, GERVASI, MASSIMO, ZANNONI, MARIO, Del Torto, F, Franceschet, C, Villa, F, Battaglia, P, Bersanelli, M, Cavaliere, F, Gervasi, M, Gregorio, A, Mennella, A, Morgante, G, Peverini, O, Pezzotta, F, Zacchei, A, Zannoni, M, GERVASI, MASSIMO, and ZANNONI, MARIO

Abstract

We present the design, manufacturing and performance verification of the Q band feed-horn array to be employed in the focal plane of the STRatospheric Italian Polarimeter (STRIP) instrument, on board the Large Scale Polarization Explorer (LSPE) balloon experiment, funded by the Italian Space Agency (ASI). LSPE will measure the polarization of the Cosmic Microwave Background (CMB) looking for the B-modes on large angular scales. The 49 feed-horns of the STRIP instrument are arranged in seven hexagonal modules of seven elements each, built in platelets technique. Measured beam patterns of each horn are highly consistent with each other and in very good agreement with simulations, at the level of fractions of a dB up to the first side-lobe. Measured crosspolarization and return loss levels are better than -37 dB and -35 dB, respectively, on a 20% bandwidth.

Published
2015

45. The effects of COVID-19 pandemic on elective post-bariatric surgery waiting list: a single Plastic Surgery Center investigation.

Author

MARRUZZO, G., REDI, U., PATANÈ, L., CAVALIERI, E., FRATTAROLI, J. M., D’ERMO, G., TORTO, F. LO, CARELLA, S., GRIPPAUDO, F. R., and RIBUFFO, D.

Abstract

OBJECTIVE: After massive weight loss, patients that meet specific criteria can be inserted in an ad-hoc post-bariatric surgery list in order to be subjected to body contouring procedures. During COVID-19 pandemic, the Italian National Health System has been overwhelmed by the continue load of life-threatening patients that needed medical assistance. Plastic surgery practice enormously scaled back during this period and this fact greatly affected elective procedures waiting lists. The aim of our study is to analyze how the lockdown and its related sanitary policies affected post-bariatric patients’ behaviors towards the delay of their procedure. PATIENTS AND METHODS: A 7-item questionnaire was administered to all patients. Change in the desire to be subjected to body contouring procedures was recorded. Smoking status, level of training during quarantine and psychological co-morbidities were also evaluated. RESULTS: 124 patients completed the questionnaire. Data analysis showed that none of them encountered a decrease of the desire to be subjected to post-bariatric plastic surgery procedures. CONCLUSIONS: The present study showed that all the patients in the waiting list did not modify their interest in being subjected to post-bariatric surgery procedures, even though the waiting time increased. [ABSTRACT FROM AUTHOR]

Published
2020

46. QUBIC: A Fizeau Interferometer Targeting Primordial B-Modes

Author

Tartari, A., primary, Aumont, J., additional, Banfi, S., additional, Battaglia, P., additional, Battistelli, E. S., additional, Baù, A., additional, Bélier, B., additional, Bennett, D., additional, Bergé, L., additional, Bernard, J. Ph., additional, Bersanelli, M., additional, Bigot-Sazy, M. A., additional, Bleurvacq, N., additional, Bordier, G., additional, Brossard, J., additional, Bunn, E. F., additional, Buzi, D., additional, Cammilleri, D., additional, Cavaliere, F., additional, Chanial, P., additional, Chapron, C., additional, Coppolecchia, A., additional, D’Alessandro, G., additional, De Bernardis, P., additional, Decourcelle, T., additional, Del Torto, F., additional, De Petris, M., additional, Dumoulin, L., additional, Franceschet, C., additional, Gault, A., additional, Gayer, D., additional, Gervasi, M., additional, Ghribi, A., additional, Giard, M., additional, Giraud-Héraud, Y., additional, Gradziel, M., additional, Grandsire, L., additional, Hamilton, J. Ch., additional, Haynes, V., additional, Holtzer, N., additional, Kaplan, J., additional, Korotkov, A., additional, Lande, J., additional, Lowitz, A., additional, Maffei, B., additional, Marnieros, S., additional, Martino, J., additional, Masi, S., additional, McCulloch, M., additional, Melhuish, S., additional, Mennella, A., additional, Montier, L., additional, Murphy, A., additional, Néel, D., additional, Ng, M. W., additional, O’Sullivan, C., additional, Pajot, F., additional, Passerini, A., additional, Perbost, C., additional, Piacentini, F., additional, Piat, M., additional, Piccirillo, L., additional, Pisano, G., additional, Prêle, D., additional, Rambaud, D., additional, Rigaut, O., additional, Salatino, M., additional, Schillaci, A., additional, Scully, S., additional, Stolpovskiy, M. M., additional, Timbie, P., additional, Tucker, G., additional, Viganò, D., additional, Voisin, F., additional, Watson, B., additional, and Zannoni, M., additional

Published
2015
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47. Oncoplastic conservative surgery for breast cancer: long-term outcomes of our first ten years experience.

Author

CALABRESE, C., CASELLA, D., DI TARANTO, G., MARCASCIANO, M., KOTHARI, A., SORDI, S., BARELLINI, L., LO TORTO, F., TARALLO, M., PERRA, A., FAUSTO, A., and RIBUFFO, D.

Abstract

OBJECTIVE: The main goal of oncoplastic breast surgery (OBS) is to optimize cosmetic outcomes and reduce patient morbidity, while still providing an oncologically-safe surgical outcome and extending the target population of conservative surgery. Although the growing number of reported experiences with oncoplastic surgery, few studies account for the long-term outcomes. PATIENTS AND METHODS: Between January 2000 and December 2010, 1024 consecutive oncoplastic surgeries were performed and prospectively included in a database. Demographic data, histological and oncological evaluation and surgical complications were recorded. The role of tumor and patients' characteristics on the development of local recurrence and metastases were assessed by multivariate analysis. RESULTS: Median follow up was 74.2 months. The average age of patients was 56.24. In 869 patients (84.9%) an invasive tumor and in 155 (15.1%) an in situ tumor (11% DCIS and 4% LIN) was found. The average size of the tumor was 24.5 mm. A positive margin was presented in 67 (6.5%) patients. Forty patients (50%) underwent re-excision and 39 (49.4%) underwent mastectomy. The overall breast conservation rate was 96.2%. Reported complications were: 17 wound infections (1.7%); 106 hematomas (10.4%); 94 lymphorrheas (9.2%), 48 partial wound dehiscence (4.7%). Local recurrences (LR) were observed in 49 patients (4.7%). The risk of local recurrence was significantly higher in the group of patients with lymphovascular invasion and with high grade (G) (p < 0.05). 52 (5.07%) distant metastases were reported and the related risk was significantly higher in the group of patients with lymphovascular invasion and with negative receptors (p < 0.05). CONCLUSIONS: Oncoplastic surgery provides an acceptable oncological long-term outcome and can be used to treat with conservative surgery also a selected population of patients who would had otherwise undergone mastectomy in the past. [ABSTRACT FROM AUTHOR]

Published
2018

48. Q-band antenna-feed system for the Large Scale Polarization Explorer balloon experiment

Author

Peverini, O A., primary, Virone, G., additional, Del Torto, F., additional, Franceschet, C., additional, Villa, F., additional, Lumia, M., additional, Farooqui, Z., additional, Mennella, A., additional, Bersanelli, M., additional, Zannoni, M., additional, Gervasi, M., additional, Addamo, G., additional, Battaglia, P., additional, Cavaliere, F., additional, Morgante, G., additional, Gregorio, A., additional, Zacchei, A., additional, and Tascone, R., additional

Published
2015
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50. The Large-Scale Polarization Explorer (LSPE)

Author

McLean, IS, Ramsay, SK, Takami, H, Aiola, S, Amico, G, Battaglia, P, Battistelli, E, Baù, A, de Bernardis, P, Bersanelli, M, Boscaleri, A, Cavaliere, F, Coppolecchia, A, Cruciani, A, Cuttaia, F, D'Addabbo, A, D'Alessandro, G, De Gregori, S, Del Torto, F, De Petris, M, Fiorineschi, L, Franceschet, C, Franceschi, E, Gervasi, M, Goldie, D, Gregorio, A, Haynes, V, Krachmalnicoff, N, Lamagna, L, Maffei, B, Maino, D, Masi, S, Mennella, A, Morgante, G, Nati, F, Ng, M, Pagano, L, Passerini, A, Peverini, O, Piacentini, F, Piccirillo, L, Pisano, G, Ricciardi, S, Rissone, P, Romeo, G, Salatino, M, Sandri, M, Schillaci, A, Stringhetti, L, Tartari, A, Tascone, R, Terenzi, L, Tomasi, M, Tommasi, E, Villa, F, Virone, G, Withington, S, Zacchei, A, Zannoni, M, D'Addabbo A, NATI, FEDERICO, Ng, M W, McLean, IS, Ramsay, SK, Takami, H, Aiola, S, Amico, G, Battaglia, P, Battistelli, E, Baù, A, de Bernardis, P, Bersanelli, M, Boscaleri, A, Cavaliere, F, Coppolecchia, A, Cruciani, A, Cuttaia, F, D'Addabbo, A, D'Alessandro, G, De Gregori, S, Del Torto, F, De Petris, M, Fiorineschi, L, Franceschet, C, Franceschi, E, Gervasi, M, Goldie, D, Gregorio, A, Haynes, V, Krachmalnicoff, N, Lamagna, L, Maffei, B, Maino, D, Masi, S, Mennella, A, Morgante, G, Nati, F, Ng, M, Pagano, L, Passerini, A, Peverini, O, Piacentini, F, Piccirillo, L, Pisano, G, Ricciardi, S, Rissone, P, Romeo, G, Salatino, M, Sandri, M, Schillaci, A, Stringhetti, L, Tartari, A, Tascone, R, Terenzi, L, Tomasi, M, Tommasi, E, Villa, F, Virone, G, Withington, S, Zacchei, A, Zannoni, M, D'Addabbo A, NATI, FEDERICO, and Ng, M W

Abstract

The LSPE is a balloon-borne mission aimed at measuring the polarization of the Cosmic Microwave Background (CMB) at large angular scales, and in particular to constrain the curl component of CMB polarization (B-modes) produced by tensor perturbations generated during cosmic inflation, in the very early universe. Its primary target is to improve the limit on the ratio of tensor to scalar perturbations amplitudes down to r = 0.03, at 99.7% confidence. A second target is to produce wide maps of foreground polarization generated in our Galaxy by synchrotron emission and interstellar dust emission. These will be important to map Galactic magnetic fields and to study the properties of ionized gas and of diffuse interstellar dust in our Galaxy. The mission is optimized for large angular scales, with coarse angular resolution (around 1.5 degrees FWHM), and wide sky coverage (25% of the sky). The payload will fly in a circumpolar long duration balloon mission during the polar night. Using the Earth as a giant solar shield, the instrument will spin in azimuth, observing a large fraction of the northern sky. The payload will host two instruments. An array of coherent polarimeters using cryogenic HEMT amplifiers will survey the sky at 43 and 90 GHz. An array of bolometric polarimeters, using large throughput multi-mode bolometers and rotating Half Wave Plates (HWP), will survey the same sky region in three bands at 95, 145 and 245 GHz. The wide frequency coverage will allow optimal control of the polarized foregrounds, with comparable angular resolution at all frequencies

Published
2012

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