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Introduction: lymphomatoid granulomatosis is a very rare disease; This is the first case reported in the hospital. Patient information: 44-year-old male, with a health history and no toxic habits, who began with respiratory symptoms, dermatological lesions, constitutional syndrome and flaccid paraplegia. Complementary examinations showed pancytopenia, and the chest xray and tomography showed an image suggestive of lung metastasis; An MRI showed a compressive lesion at the dorsal level. The anatomopathological studies of the skin and lung showed a lymphomatoid granulomatosis with medullary invasion. The patient was treated with chemotherapy and died abruptly one month after it began. Conclusions: lymphomatoid granulomatosis is a rare disease currently considered a lymphoid neoplasm associated with Epstein-Barr virus and large B cell lymphoma. It occurs in this patient accompanied by neurological injury; The diagnosis was only possible by anatomopathological studies. It was impossible to perform an autopsy due to family refusal. [ABSTRACT FROM AUTHOR]

Hepatic angiosarcoma is a rare malignancy whose incidence is reported to be from 0.5% to 2% of primary liver tumors. Late diagnosis is defined as diagnosis after the liver has been compromised and surgical therapy is no longer possible. Most hepatic angiosarcomas (75%) are idiopathic, and clinical and radiological findings are nonspecific. Diagnosis is mainly by histopathology. We report the case of a 34-year-old male patient with no history of interest who had had a liver tumor for four months without specific symptoms. Cardiovascular disturbances led to death by cardiac failure. An autopsy and histopathology revealed liver angiosarcoma that had metastasized to the heart and pleural cavity. [ABSTRACT FROM AUTHOR]

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The case of a 21-year female patient with a solid-pseudopapillary tumor of the Pancreas is presented. Clinical, histopathological, diagnostic and therapeutic features of this rare tumor are presented and discussed with emphasis on pathology and differential diagnosis. This rare entity most frequently affects young women, but its incidence has increasing, and there have been changes its clinical behavior from those classically reported. [ABSTRACT FROM AUTHOR]

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract. Historically, these lesions were classified as leiomyomas or leiomyosarcomas, but the actual cell of origin of GISTs is a pluripotential mesenchymal stem cell programmed to differentiate into the interstitial cell of Cajal. These advances have led to the classification of GISTs as an entity separate from smooth muscle tumors. The case of 39-year-male patient with the diagnosis of gastrointestinal stromal tumor of the small intestine is presented. The clinical manifestations, epidemiology and immunohistochemical diagnostic features are discussed. Finally, differential diagnosis and therapeutics are exposed. We stood out the importance of the surgical management and Imatinib (Glivec) in these tumors. [ABSTRACT FROM AUTHOR]