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16 results on '"Torres, Clinton"'

1. Contributors

Author

Allen, Jonathan, primary, Bahr, Elizabeth L., additional, Bailey, Hazel, additional, Arunmozhi Balajee, S., additional, Barnaby, Neel G., additional, Barr, John R., additional, Breeze, Roger G., additional, Brewer, Luke N., additional, Budowle, Bruce, additional, Bull, Robert L., additional, Burans, James P., additional, Bush, Robin M., additional, Carrillo, Consuelo, additional, Cebula, Thomas A., additional, Chakraborty, Ranajit, additional, Clowers, Brian H., additional, Dasch, Gregory A., additional, Duncan, David D., additional, Ecker, David J., additional, Engelthaler, David M., additional, Eremeeva, Marina E., additional, Eshoo, Mark W., additional, Fletcher, Jacqueline, additional, Foster, Jeffrey T., additional, Florian Fricke, W., additional, Gardner, Shea, additional, Harmon, Rockne P., additional, Hill, Karen H., additional, Jaing, Crystal, additional, Johnson, Rudolph C., additional, Kalb, Suzanne R., additional, Kaufmann, Arnold F., additional, Keim, Paul S., additional, Khan, Ali S., additional, Kotula, Paul G., additional, Kramer, Melissa, additional, Leighton, Terrance, additional, Ian Lipkin, W., additional, Loftus, Ronan T., additional, Marks, James D., additional, Massung, Robert F., additional, Richard McCombie, W., additional, Meghen, Ciaran, additional, Melcher, Ulrich, additional, Melling, Jack, additional, Michael, Joseph R., additional, Morse, Stephen A., additional, Murch, Randall S., additional, Murray, Catherine L., additional, Nutter, Forrest W., additional, Ochoa Corona, Francisco M., additional, Oh, Thomas S., additional, Okinaka, Richard T., additional, Parla, Jennifer, additional, Pearson, Talima, additional, Pesenti, Peter T., additional, Pesik, Nicki, additional, Picuri, John, additional, Ravel, Jacques, additional, Rice, Charles M., additional, Robertson, James, additional, Roffey, Paul E., additional, Saathoff, Gregory B., additional, Schouten, Ronald, additional, Schutzer, Steven E., additional, Sharma, Sushil K., additional, Skowronski, Evan, additional, Slezak, Tom, additional, Smith, Jenifer A.L., additional, Smith, Noel H., additional, Thomas, Carla, additional, Torres, Clinton, additional, Torres, Marisa, additional, Tuanyok, Apichai, additional, Velsko, Stephan P., additional, Vitalis, Elizabeth, additional, Vogler, Amy J., additional, Wagner, David M., additional, Wahl, Karen L., additional, Weirich, Elizabeth, additional, Wilson, Mark, additional, and Wunschel, David S., additional

Published
2011
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4. LAVA: An Open-Source Approach To Designing LAMP (Loop-Mediated Isothermal Amplification) DNA Signatures

Author

Gardner Shea N, Baker Brian R, Vitalis Elizabeth A, Torres Clinton, Torres Marisa W, and Dzenitis John M

Subjects
Computer applications to medicine. Medical informatics, R858-859.7, Biology (General), QH301-705.5
Abstract

Abstract Background We developed an extendable open-source Loop-mediated isothermal AMPlification (LAMP) signature design program called LAVA (LAMP Assay Versatile Analysis). LAVA was created in response to limitations of existing LAMP signature programs. Results LAVA identifies combinations of six primer regions for basic LAMP signatures, or combinations of eight primer regions for LAMP signatures with loop primers, which can be used as LAMP signatures. The identified primers are conserved among target organism sequences. Primer combinations are optimized based on lengths, melting temperatures, and spacing among primer sites. We compare LAMP signature candidates for Staphylococcus aureus created both by LAVA and by PrimerExplorer. We also include signatures from a sample run targeting all strains of Mycobacterium tuberculosis. Conclusions We have designed and demonstrated new software for identifying signature candidates appropriate for LAMP assays. The software is available for download at http://lava-dna.googlecode.com/.

Published
2011
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5. Design of Genomic Signatures for Pathogen Identification and Characterization

Author

Slezak, Tom, Gardner, Shea, Allen, Jonathan, Vitalis, Elizabeth, Torres, Marisa, Torres, Clinton, and Jaing, Crystal

Subjects
Article
Abstract

Publisher Summary This chapter addresses issues associated with the identification of signatures based on genomic DNA/RNA, which can be used to identify and characterize pathogens for biodefense and microbial forensic goals. Genomic signature-based identification techniques have the advantage of being precise, highly sensitive, and relatively fast in comparison to biochemical typing methods and protein signatures. Classic biochemical typing methods were developed long before knowledge of DNA and resulted in dozens of tests that are used to roughly characterize the major known pathogens. Genomic signatures can be intended for many different purposes and applied at multiple different resolutions. Organism signatures are intended to uniquely identify the organisms involved. Mechanism signatures can be best thought of as identifying particular genes that result in functional properties such as virulence, antibiotic resistance, or host range. The primary reason to identify mechanisms, independent of organisms, is to detect potential genetic engineering. A secondary reason is that nature has shared many important mechanisms on its own over the millennia, and thus they may not be sufficiently unique to identify specific organisms. Method signatures present yet another dimension of analyzing pathogens: evidence of potential bacterial genetic engineering may be seen in a genome by checking for traces of the bacterial vectors that may have been used to insert one or more foreign genes and related components into the genome being modified.

Published
2010

6. Draft Genome Sequences from a Novel Clade of Bacillus cereus Sensu Lato Strains, Isolated from the International Space Station

Author

Venkateswaran, Kasthuri, primary, Checinska Sielaff, Aleksandra, additional, Ratnayake, Shashikala, additional, Pope, Robert K., additional, Blank, Thomas E., additional, Stepanov, Victor G., additional, Fox, George E., additional, van Tongeren, Sandra P., additional, Torres, Clinton, additional, Allen, Jonathan, additional, Jaing, Crystal, additional, Pierson, Duane, additional, Perry, Jay, additional, Koren, Sergey, additional, Phillippy, Adam, additional, Klubnik, Joy, additional, Treangen, Todd J., additional, Rosovitz, M. J., additional, and Bergman, Nicholas H., additional

Published
2017
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11. A Multiplex Real-Time Reverse Transcription Polymerase Chain Reaction Assay for Detection and Differentiation of Bluetongue Virus and Epizootic Hemorrhagic Disease Virus Serogroups

Author

Wilson, William C., primary, Hindson, Benjamin J., additional, O'Hearn, Emily S., additional, Hall, Sara, additional, Tellgren-Roth, Christian, additional, Torres, Clinton, additional, Naraghi-Arani, Pejman, additional, Mecham, James O., additional, and Lenhoff, Raymond J., additional

Published
2009
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13. Comparative genomics tools applied to bioterrorism defence.

Author

Slezak, Tom, Kuczmarski, Tom, Ott, Linda, Torres, Clinton, Medeiros, Dan, Smith, Jason, Truitt, Brian, Mulakken, Nisha, Lain, Marisa, Vitalis, Elizabeth, Zemla, Adam, Zhou, Carol Ecale, and Gardner, Shea

Subjects
GENOMICS, PATHOGENIC bacteria, VIRUSES, LABORATORIES
Abstract

Rapid advances in the genomic sequencing of bacteria and viruses over the past few years have made it possible to consider sequencing the genomes of all pathogens that affect humans and the crops and livestock upon which our lives depend. Recent events make it imperative that full genome sequencing be accomplished as soon as possible for pathogens that could be used as weapons of mass destruction or disruption. This sequence information must be exploited to provide rapid and accurate diagnostics to identify pathogens and distinguish them from harmless near-neighbours and hoaxes. The Chem-Bio Non-Proliferation (CBNP) programme of the US Department of Energy (DOE) began a large-scale effort of pathogen detection in early 2000 when it was announced that the DOE would be providing bio-security at the 2002 Winter Olympic Games in Salt Lake City, Utah. Our team at the Lawrence Livermore National Lab (LLNL) was given the task of developing reliable and validated assays for a number of the most likely bioterrorist agents. The short timeline led us to devise a novel system that utilised whole-genome comparison methods to rapidly focus on parts of the pathogen genomes that had a high probability of being unique. Assays developed with this approach have been validated by the Centers for Disease Control (CDC). They were used at the 2002 Winter Olympics, have entered the public health system, and have been in continual use for non-publicised aspects of homeland defence since autumn 200 I. Assays have been developed for all major threat list agents for which adequate genomic sequence is available, as well as for other pathogens requested by various government agencies... [ABSTRACT FROM AUTHOR]

Published
2003
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14. Comportamientos suicidas

Author

Ramón Illán Bacca, Guillermo Henríquez Torres Clinton Ramírez Contreras, Ramón Illán Bacca, Ramón Illán Bacca, Guillermo Henríquez Torres Clinton Ramírez Contreras, and Ramón Illán Bacca

Abstract

WORLD

15. Comportamientos suicidas

Author

Ramón Illán Bacca, Guillermo Henríquez Torres Clinton Ramírez Contreras, Ramón Illán Bacca, Ramón Illán Bacca, Guillermo Henríquez Torres Clinton Ramírez Contreras, and Ramón Illán Bacca

Abstract

WORLD

16. Comportamientos suicidas

Author

Ramón Illán Bacca, Guillermo Henríquez Torres Clinton Ramírez Contreras, Ramón Illán Bacca, Ramón Illán Bacca, Guillermo Henríquez Torres Clinton Ramírez Contreras, and Ramón Illán Bacca

Abstract

WORLD

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