Search

Your search keyword '"Toro, Laura"' showing total 202 results
Start Over Author "Toro, Laura"
202 results on '"Toro, Laura"'

3. Tropical root responses to global changes: A synthesis.

Author

Yaffar, Daniela, Lugli, Laynara F., Wong, Michelle Y., Norby, Richard J., Addo‐Danso, Shalom D., Arnaud, Marie, Cordeiro, Amanda L., Dietterich, Lee H., Diaz‐Toribio, Milton H., Lee, Ming Y., Ghimire, Om Prakash, Smith‐Martin, Chris M., Toro, Laura, Andersen, Kelly, McCulloch, Lindsay A., Meier, Ina C., Powers, Jennifer S., Sanchez‐Julia, Mareli, Soper, Fiona M., and Cusack, Daniela F.

Subjects
TROPICAL ecosystems, TROPICAL forests, PLANT metabolism, BIOMASS, PLANT nutrients
Abstract

Tropical ecosystems face escalating global change. These shifts can disrupt tropical forests' carbon (C) balance and impact root dynamics. Since roots perform essential functions such as resource acquisition and tissue protection, root responses can inform about the strategies and vulnerabilities of ecosystems facing present and future global changes. However, root trait dynamics are poorly understood, especially in tropical ecosystems. We analyzed existing research on tropical root responses to key global change drivers: warming, drought, flooding, cyclones, nitrogen (N) deposition, elevated (e) CO2, and fires. Based on tree species‐ and community‐level literature, we obtained 266 root trait observations from 93 studies across 24 tropical countries. We found differences in the proportion of root responsiveness to global change among different global change drivers but not among root categories. In particular, we observed that tropical root systems responded to warming and eCO2 by increasing root biomass in species‐scale studies. Drought increased the root: shoot ratio with no change in root biomass, indicating a decline in aboveground biomass. Despite N deposition being the most studied global change driver, it had some of the most variable effects on root characteristics, with few predictable responses. Episodic disturbances such as cyclones, fires, and flooding consistently resulted in a change in root trait expressions, with cyclones and fires increasing root production, potentially due to shifts in plant community and nutrient inputs, while flooding changed plant regulatory metabolisms due to low oxygen conditions. The data available to date clearly show that tropical forest root characteristics and dynamics are responding to global change, although in ways that are not always predictable. This synthesis indicates the need for replicated studies across root characteristics at species and community scales under different global change factors. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

4. Toward a coordinated understanding of hydro‐biogeochemical root functions in tropical forests for application in vegetation models

Author

Cusack, Daniela F., primary, Christoffersen, Bradley, additional, Smith‐Martin, Chris M., additional, Andersen, Kelly M., additional, Cordeiro, Amanda L., additional, Fleischer, Katrin, additional, Wright, S. Joseph, additional, Guerrero‐Ramírez, Nathaly R., additional, Lugli, Laynara F., additional, McCulloch, Lindsay A., additional, Sanchez‐Julia, Mareli, additional, Batterman, Sarah A., additional, Dallstream, Caroline, additional, Fortunel, Claire, additional, Toro, Laura, additional, Fuchslueger, Lucia, additional, Wong, Michelle Y., additional, Yaffar, Daniela, additional, Fisher, Joshua B., additional, Arnaud, Marie, additional, Dietterich, Lee H., additional, Addo‐Danso, Shalom D., additional, Valverde‐Barrantes, Oscar J., additional, Weemstra, Monique, additional, Ng, Jing Cheng, additional, and Norby, Richard J., additional

Published
2024
Full Text
View/download PDF

6. Absenteeism, Burnout and Symptomatology of Teacher Stress: Sex Differences

Author

Bermejo-Toro, Laura and Prieto-Ursúa, María

Abstract

Although numerous studies have been carried out confirming high levels in symptomatology of stress and depression in the teaching profession, research focusing on sex differences in these problems has been both scarce and inconclusive. The aim of this study is to analyse differences with regards to sex in the incidence of absenteeism, work-related stress, symptomatology of depression, level of burnout and psychiatric symptomatology. The sample consists of 71 Secondary teachers, 31 men and 40 women. The tools used were the Questionnaire of Teacher Burnout (CBP-R), the Beck Depression Inventory (BDI), the Symptomatology Checklist-90-R (SCL-90-R) and a socio-demographic and work-situation questionnaire. Results showed sex differences only in the types of illness that caused sick leaves in men (50% otorhinolaringologycal) and in women (50% psychiatric), and in some of the correlations between Role Stress-Burnout and psychiatric symptomatology that were higher for women than for men. In conclusion, this research supports the results of other studies that have not found different patterns of stress, burnout and depression between female and male teachers.

Published
2014

7. H1 histones control the epigenetic landscape by local chromatin compaction

Author

Willcockson, Michael A., Healton, Sean E., Weiss, Cary N., Bartholdy, Boris A., Botbol, Yair, Mishra, Laxmi N., Sidhwani, Dhruv S., Wilson, Tommy J., Pinto, Hugo B., Maron, Maxim I., Skalina, Karin A., Toro, Laura Norwood, Zhao, Jie, Lee, Chul-Hwan, Hou, Harry, Yusufova, Nevin, Meydan, Cem, Osunsade, Adewola, David, Yael, Cesarman, Ethel, Melnick, Ari M., Sidoli, Simone, Garcia, Benjamin A., Edelmann, Winfried, Macian, Fernando, and Skoultchi, Arthur I.

Published
2021
Full Text
View/download PDF

8. 'I Want to Study Psychology': Vocational Interests and Values of University Preparatory Students with a Preference for Studying Psychology

Author

Hernández-Franco, Vicente, Baena, Belén Charro, Prieto-Ursúa, María, and Toro, Laura Bermejo

Abstract

Introduction: The aim of this study was to explore the specific vocational identity of secondary school students whose first choice of degree program is Psychology. In particular, this study analyzes when their interest in Psychology began, the curriculum track taken in high school and their profile of vocational interests and values. Method: The sample was made up of 4715 subjects in their final year of secondary education at public or private schools in the Greater Madrid region (Spain); 43.9% were male, and the mean age was 17.38 years (SD = 0.64). Subjects completed the Project Orion battery of guidance questionnaires. A subsample of 509 students wished to study Psychology; their mean age was 17.38 years (SD = 0.69), and 76.2% were female. Results: The results showed significant differences in the profile of vocational interests and values of students who wished to study Psychology, in comparison to the others. Specifically, students opting for Psychology showed greater interest in the area of Healthcare, followed by interests in the vocational area of Teaching and Guidance. Furthermore, the vocational values that characterize students who wish to study Psychology were: "Helping people," "Doing something useful and important" and "Pursuing higher values." The guidance they had received from teachers and school counselors about which curriculum track to follow in upper secondary school was appropriate.

Published
2018
Full Text
View/download PDF

9. Cost‐effectiveness of management strategies in a nucleation experiment in a tropical dry forest.

Author

Toro, Laura, Torres‐Romero, Francisco, Salinas, Sandra M., Avella‐Munoz, Andrés, Galatowish, Susan, Secchi, Silvia, and Powers, Jennifer S.

Subjects
*TROPICAL dry forests, *FOREST succession, *NATIVE species, *TROPICAL forests, *NUCLEATION, *FERTIGATION
Abstract

Cost‐effective, large‐scale strategies are needed to restore degraded ecosystems worldwide. Applied nucleation is one technique that can accelerate succession in tropical forests. However, the effectiveness of irrigation and fertilization in the context of large‐scale applied nucleation in tropical dry forests (TDFs) has not yet been tested. To this end, we established a large‐scale experiment in southwestern Colombia on abandoned pastures. We planted 11,382 seedlings of 11 native species coupled with six management treatments that varied in the amounts of fertilizer and water. We monitored survival, height, and resprouting ability seedlings over 2 years. We also estimated the cost of seedling production, planting procedures, management, and monitoring, and assessed their cost‐effectiveness using seedling survival as an indication of effectiveness. After 2 years, 73% (8,266) of seedlings planted survived, and species survival ranged from 5 to 99%. Individuals that received the lowest amount of fertilizer (25 g of Nitrogen, Phosphorus, and Potassium [NPK]) with additional irrigation had the highest survival rates (>76%). Final height ranged from 52 to 330 cm across species. Seedlings that received the highest amount of fertilizer (50 g of NPK) without additional irrigation had the highest mean final height (174 ± 9.0 cm). The control was cheapest ($7313/ha) and the most cost‐effective method in terms of seedling survival. Our findings suggest that the best way to establish cost‐effective, large‐scale restoration projects in TDFs is to plant native species mixtures of locally adapted species without fertilization and irrigation and to invest in long‐term monitoring. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

10. Belowground foundations of tropical forest restoration.

Author

McCulloch, Lindsay A., Prada, Cecilia M., Liao, Wenying, Bauters, Marijn, Church, Lauren, Lee, Ming Yang, Toro, Laura, Van de Velde, Viktor, Weissflog, Anita, Wong, Michelle, and Taylor, Benton N.

Subjects
TROPICAL forests, FOREST restoration, MICROBIAL inoculants, NITROGEN fixation, EARTH system science, BOTANY, NUTRIENT cycles, FOREST management
Abstract

This article explores the significance of belowground processes in tropical forest restoration and offers recommendations for further understanding these processes. It emphasizes the role of plant-root interactions, soil microbes, and soil properties in driving essential ecosystem services such as erosion control, nutrient cycling, and carbon sequestration. The article highlights the importance of plant-microbe interactions in forest recovery and proposes management strategies for soil stabilization, carbon storage, nutrient cycling, and forest diversity. It also stresses the selection of native mycorrhizal communities and cautions against using non-native soil inoculum. The authors argue that incorporating belowground research into land management strategies can enhance the effectiveness of restoration projects, while also emphasizing the need for collaboration between scientists and restoration practitioners and the consideration of ecological, economic, and social factors in restoration areas. [Extracted from the article]

Published
2024
Full Text
View/download PDF

11. Screening for obstructive sleep apnea in patients with Down Syndrome

Author

Fortuna Gutierrez, Ana, primary, Podzamczer Valls, Ines, additional, Mayos Pérez, Mercè, additional, Clos Batet, Susana, additional, Videla Toro, Laura, additional, Carmona-Iragui, Maria, additional, Barroeta Espar, Isabel, additional, Arranz Martinez, Javier José, additional, Benejam Paul, Bessy, additional, Lleó Bisa, Alberto, additional, Fortea Ormaechea, Juan, additional, and Giménez Badia, Sandra, additional

Published
2023
Full Text
View/download PDF

15. Towards a Model of Teacher Well-Being: Personal and Job Resources Involved in Teacher Burnout and Engagement

Author

Bermejo-Toro, Laura, Prieto-Ursúa, María, and Hernández, Vicente

Abstract

Although much research has focused on the role of job demands and job resources in teacher well-being, few studies have targeted the function of personal variables. The aim of this study is to develop a comprehensive model of teacher well-being, using burnout and engagement in order to reflect, not only job demands and professional resources, but particularly the personal resources that characterise teacher well-being: self-efficacy, and cognitive and behavioural coping resources (proactive and reactive) related to three specific situational demands. Job resources were: autonomy, social support from colleagues and supervisors, and variety and feedback provision at work. Participants were 413 teachers from 47 elementary, primary and secondary schools in Madrid (Spain). The results show paths between the significant variables of the model in the anticipated direction. A line of influence starts in perceived demands and perceived self-efficacy, and is modulated by coping. This generates some degree of teacher well-being, which in turn is affected by teachers' available job resources. Engagement seems to have a considerable effect on burnout.

Published
2016
Full Text
View/download PDF

17. Neuropsychological and fluid biomarker changes in the Alzheimer's disease continuum in adults with Down syndrome

Author

Videla Toro, Laura, Fortea Ormaechea, Juan, Vidal Ces, Sebastia, and Lleó Bisa, Alberto

Subjects
Malaltia d'Alzheimer, Cognición, Cognition, 616.8, Enfermedad de Alzheimer, Síndrome de Down, Cognició, Down sindrome, Alzheimer's disease, Ciències de la Salut
Abstract

La síndrome de Down (SD) és la causa més freqüent de discapacitat intel·lectual (DI) d'origen genètic i està causada per la triplicació del cromosoma 21. Alguns dels gens codificats en aquest cromosoma, principalment el de la proteïna precursora de l'amiloide (APP), fan que aquestes persones presentin les marques fisiopatològics de la malaltia d'Alzheimer (MA) a partir dels 40 anys i que, per tant, tinguin un elevadíssim risc de desenvolupar una demència per MA. No obstant, el diagnòstic clínic de la demència en aquesta població és un repte degut a la DI premòrbida associada a la pròpia SD, a la manca de criteris diagnòstics adaptats, i a la manca de dades normatives dels tests neuropsicològics. Actualment no hi ha tractaments per prevenir o curar la MA i, a més, les persones amb SD han estat històricament excloses dels assaigs clínics i la recerca, negant-los l'oportunitat de beneficiar-se de possibles tractaments i avenços científics. L'objectiu d'aquesta tesi doctoral es centra en la caracterització del curs clínic i cognitiu de la MA en aquesta població i en l'estudi del rendiment diagnòstic i pronòstic de diferents biomarcadors de fluids en plasma i líquid cefaloraquidi (LCR). Per fer-ho, ens hem basat en dades de la cohort més gran d'arreu del món d'adults amb la SD per l'estudi de la MA, la cohort Down Alzheimer Barcelona Neuroimaging Initiative (DABNI). Concretament, descrivim com entre la població adulta amb la SD és quasi inevitable la progressió cap a la fase de demència de la MA a mida que envelleixen i, especialment, a partir de la quinta dècada de vida. Així, posem de manifest la urgent necessitat de dissenyar plans de salut i assaigs clínics específics contra la MA per aquesta població. D'aquesta manera, serà imprescindible validar eines neuropsicològiques i definir uns criteris diagnòstics adaptats a persones amb la SD. En contra del que s'ha assumit fins al moment en el camp de la DI, i de la síndrome de Down en particular, en la present tesi demostrem que és factible avaluar el deteriorament cognitiu de la MA es pot diagnosticar amb una avaluació transversal. A més, mostrem la viabilitat de monitoritzar el rendiment cognitiu de les persones amb la SD al llarg d'un assaig clínic preventiu validant dues eines neuropsicològiques com a variables d'eficàcia (endpoints) cognitives, imprescindibles en qualsevol assaig clínic per la MA. Finalment, en un context on els biomarcadors han revolucionat la manera de diagnosticar la MA en la població general, destaquem la necessitat d'adaptar aquests avenços per aplicar-los a la població amb la SD. En aquest sentit, hem validat el rendiment diagnòstic i pronòstic dels neurofilaments de cadena lleugera (NfL) en plasma per la detecció de la MA en la SD i hem explorat un panell de proteïnes sinàptiques en líquid cefaloraquidi (LCR) com a possibles biomarcadors de la MA que podrien ser útils per monitoritzar la resposta terapèutica assaigs clínics. En resum, les dades presentades en aquesta tesi doctoral s'han centrat en el diagnòstic de les fases simptomàtiques de la MA i en l'estudi dels canvis clínics, cognitius i de biomarcadors de la malaltia en adults amb la SD. Estudis multimodals com els presentats en aquesta recull són essencials per avançar en el coneixement de la història natural de la MA, per desenvolupar noves eines diagnòstiques precises i, potencialment, per descobrir noves dianes terapèutiques. El síndrome de Down (SD) es la causa más frecuente de discapacidad intelectual (DI) de origen genético y está causada por la triplicación del cromosoma 21. Algunos de los genes codificados en este cromosoma, principalmente el de la proteína precursora del amiloide (APP), son los responsables de que estas personas presenten las marcas fisiopatológicos de la enfermedad de Alzheimer (EA) a partir de los 40 años y que, por tanto, tengan un elevadísimo riesgo de desarrollar una demencia por EA. Sin embargo, el diagnóstico clínico de la demencia en esta población es un reto debido a la DI premórbida asociada al propio SD, a la falta de criterios diagnósticos adaptados y a la falta de datos normativos de los test neuropsicológicos. Actualmente no existen tratamientos para prevenir o curar la EA y, además, las personas con SD han sido históricamente excluidas de los ensayos clínicos y la investigación, negándoles la oportunidad de beneficiarse de posibles tratamientos y de los avances científicos. El objetivo de esta tesis doctoral se centra en la caracterización del curso clínico y cognitivo de la EA en esta población y en el estudio del rendimiento diagnóstico y pronóstico de diferentes biomarcadores de fluidos en plasma y líquido cefalorraquídeo (LCR). Para ello, nos hemos basado en datos de la mayor cohorte del mundo de adultos con SD para el estudio de la EA, la cohorte Down Alzheimer Barcelona Neuroimaging Initiative (DABNI). Concretamente, describimos cómo entre la población adulta con SD es casi inevitable la progresión hacia la fase de demencia de la EA a medida que envejecen y, especialmente, a partir de la quinta década de vida. Así, ponemos de manifiesto la urgente necesidad de diseñar planes de salud y ensayos clínicos específicos contra la EA para esta población. De esta forma, será imprescindible validar herramientas neuropsicológicas y definir unos criterios diagnósticos adaptados a personas con SD. En contra de lo asumido hasta el momento en el campo de la DI, y del síndrome de Down en particular, en la presente tesis demostramos que es factible evaluar el deterioro cognitivo asociado a la EA con una evaluación transversal. Además, mostramos la viabilidad de monitorizar el rendimiento cognitivo de las personas con SD a lo largo de un ensayo clínico preventivo, validando dos herramientas neuropsicológicas como variables de eficacia (endpoints) cognitivas, imprescindibles en cualquier ensayo clínico para la EA. Por último, en un contexto en el que los biomarcadores han revolucionado la manera de diagnosticar la EA en la población general, destacamos la necesidad de adaptar estos avances para aplicarlos a la población con SD. En este sentido, hemos validado el rendimiento diagnóstico y pronóstico de los neurofilamentos de cadena ligera (NfL) en plasma para la detección de la EA en el SD y hemos explorado un panel de proteínas sinápticas en líquido cefalorraquídeo (LCR) como posibles biomarcadores de la EA que podrían ser útiles para monitorizar la respuesta terapéutica en ensayos clínicos. En resumen, los datos presentados en esta tesis doctoral se han centrado en el diagnóstico de las fases sintomáticas de la EA y en el estudio de los cambios clínicos, cognitivos y de biomarcadores de la enfermedad en adultos con SD. Estudios multimodales como los presentados en este compendio son esenciales para avanzar en el conocimiento de la historia natural de la EA, para desarrollar nuevas herramientas diagnósticas precisas y, potencialmente, para descubrir nuevas dianas terapéuticas. Down syndrome (DS) is the most common cause of intellectual disability (ID) of genetic origin, and it is caused by the triplication of the chromosome 21. Some genes coded in this chromosome such as the amyloid precursor protein (APP), lead to the universal presence of Alzheimer's disease (AD) pathological hallmarks in adults with DS by the age of 40, and, subsequently, to an ultra-high risk to develop AD dementia. However, the clinical diagnosis of dementia in individuals with DS is a challenge due to the associated neurodevelopmental ID, and the lack of validated clinical criteria and neuropsychological normative data to diagnose symptomatic AD. Currently, there are no treatments to prevent or stop AD in this population, and adults with DS have historically been excluded from AD clinical trials and research denying them the opportunity to benefit from potential treatments and scientific breakthroughs. This doctoral thesis aimed to better characterize the clinical and cognitive course of AD in this population, and to study the performance of different fluid biomarkers in plasma and cerebrospinal fluid (CSF). Our data is based on the Down Alzheimer Barcelona Neuroimaging Initiative (DABNI) cohort of adults with DS, the largest cohort for the study of AD in DS worldwide. Our works have shown the nearly inevitable progression to symptomatic AD with age from the fourth decade of life in this population, highlighting the urgent need for the design of health plans and clinical trials against AD in individuals with DS. In this sense, a prerequisite is to validate neuropsychological tools and define clinical diagnostic criteria for AD in DS. In contrast with previous assumptions, we demonstrate that cognitive assessment is feasible in adults with DS, and that AD-related cognitive decline can be detected with excellent accuracy in single-points evaluations. Moreover, we also showed the feasibility of performing longitudinal cognitive assessments for the duration of preventive clinical trials and validate the performance of two commonly used neuropsychological tools to be used as cognitive endpoints, which are essential in AD clinical trials. Finally, biomarkers have revolutionized the diagnosis of AD in the general population. These advances must be adapted and applied in DS. In this regard, we have validated the diagnostic and prognostic performance of plasma NfL and have explored a panel of synaptic proteins in CSF as novel biomarkers for AD in DS that may be useful to monitor therapeutic response in AD clinical trials. In brief, the data presented in this thesis has focused on the diagnosis of symptomatic AD and the study of clinical, cognitive, and biomarker changes of AD in adults with DS. These multimodal approaches are essential to provide new insights to the natural history of AD, to establish accurate diagnostic tools, and, potentially, to discover new therapeutic targets.

Published
2023

18. Dimensions of good palliative nursing care: Expert panel consensus and perceptions of palliative professionals.

Author

Zulueta Egea, Mar, Prieto‐Ursúa, María, Bermejo Toro, Laura, and Palmar‐Santos, Ana María

Subjects
PALLIATIVE care nursing, MEDICAL quality control, EXPERIMENTAL design, RESEARCH, NURSES' attitudes, NURSING, PALLIATIVE care nurses, RESEARCH methodology, RESEARCH methodology evaluation, MATHEMATICAL models, INTERVIEWING, MULTITRAIT multimethod techniques, QUALITATIVE research, THEORY, COMMUNICATION, QUESTIONNAIRES, EMPIRICAL research, THEMATIC analysis, NEEDS assessment, DELPHI method, MEDICAL needs assessment
Abstract

Aims and Objectives: To analyse the dimensions of quality of palliative nursing care and to explore the perceptions of professionals for the development and validation of the Palliative Nursing Care Quality Scale. Background: The study of palliative nursing care quality has been approached from analysis of the competencies of palliative care nurses, based on various theoretical models. However, there are fewer qualitative empirical studies that have evaluated what good palliative nursing care is and what its dimensions are. Design: Mixed‐method, Delphi approach and exploratory qualitative study. Methods: Consensus by a panel of experts using the Delphi technique and semi‐structured interviews. The study was reported in a comprehensive manner following COREQ criteria. Data collection took place between January and June 2018. Results: The eight‐person expert panel reached consensus on the following dimensions of the Palliative Nursing Care Quality Scale: control and relief of symptoms, family and/or primary caregiver, therapeutic relationship, spiritual support and continuity of care. Thematic analysis of ten interviews identified four emergent themes related to good nursing care: (1) the patient and family as a whole; (2) finding meaning; (3) responsible communication; and (4) caring for the human element. Conclusions: The quality of palliative nursing care goes beyond providing comprehensive care; it means meticulously looking after every detail of what is important to the patient. The expectations of professionals are not as important. Instead, care should be based primarily on the needs and respect for the wishes of the patient and their family. Relevance to Clinical Practice: Specifying the quality of nursing care in routine practice and reaching a consensus on its dimensions means moving towards excellence in care, as well as improving the professional profile of advanced practice palliative care nurses. Patient or Public Contribution: Two primary caregivers participated in the panel of experts and the semi‐structured interview. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

23. Queratosis liquenoide crónica

Author

González Godoy, Daniela, primary, Kinzel Maluje, Francisca, additional, Gaona, Constanza Ullrich, additional, Toro, Laura Carreño, additional, and Duran, Ligia Aranibar, additional

Published
2022
Full Text
View/download PDF

24. Leaf habit affects the distribution of drought sensitivity but not water transport efficiency in the tropics

Author

Vargas G., German, primary, Kunert, Norbert, additional, Hammond, William M., additional, Berry, Z. Carter, additional, Werden, Leland K., additional, Smith‐Martin, Chris M., additional, Wolfe, Brett T., additional, Toro, Laura, additional, Mondragón‐Botero, Ariadna, additional, Pinto‐Ledezma, Jesús N., additional, Schwartz, Naomi B., additional, Uriarte, María, additional, Sack, Lawren, additional, Anderson‐Teixeira, Kristina J., additional, and Powers, Jennifer S., additional

Published
2022
Full Text
View/download PDF

25. Angioleiomioma cutáneo acral

Author

Kinzel Maluje, Francisca, primary, González Godoy, Daniela, additional, Araya Bertucci, Irene, additional, and Carreño Toro, Laura, additional

Published
2022
Full Text
View/download PDF

28. VAMP-2 is a surrogate cerebrospinal fluid marker of Alzheimer-related cognitive impairment in adults with Down syndrome

Author

Lleó, Alberto, Carmona Iragui, María, Videla Toro, Laura, Fernández, Susana, Benejam, Bessy, Pegueroles, Jordi, Barroeta, Isabel, Altuna-Azkargorta, Miren, Valldeneu, Silvia, Xiao, Mei-Fang, Xu, Desheng, Núñez-Llaves, Raúl, Querol-Vilaseca, Marta, Sirisi Dolcet, Sonia, Bejanin, Alexandre, Iulita, M. Florencia, Clarimón, Jordi, Blesa, Rafael, Worley, Paul, Alcolea, Daniel, Fortea, Juan, Belbin, Olivia, and Universitat Autònoma de Barcelona

Subjects
0301 basic medicine, Oncology, Adult, medicine.medical_specialty, Down syndrome, Neurology, Vesicle-Associated Membrane Protein 2, Cognitive Neuroscience, Cognitive decline, tau Proteins, Neurosciences. Biological psychiatry. Neuropsychiatry, Asymptomatic, 03 medical and health sciences, 0302 clinical medicine, Cerebrospinal fluid, Alzheimer Disease, Internal medicine, medicine, Dementia, Humans, Cognitive Dysfunction, Effects of sleep deprivation on cognitive performance, RC346-429, Amyloid beta-Peptides, business.industry, Research, Biomarker, Alzheimer's disease, medicine.disease, Synapse, Peptide Fragments, 030104 developmental biology, Biomarker (medicine), Neurology (clinical), Neurology. Diseases of the nervous system, medicine.symptom, business, Alzheimer’s disease, 030217 neurology & neurosurgery, Biomarkers, RC321-571
Abstract

BackgroundThere is an urgent need for objective markers of Alzheimer’s disease (AD)-related cognitive impairment in people with Down syndrome (DS) to improve diagnosis, monitor disease progression, and assess response to disease-modifying therapies. Previously, GluA4 and neuronal pentraxin 2 (NPTX2) showed limited potential as cerebrospinal fluid (CSF) markers of cognitive impairment in adults with DS. Here, we compare the CSF profile of a panel of synaptic proteins (Calsyntenin-1, Neuroligin-2, Neurexin-2A, Neurexin-3A, Syntaxin-1B, Thy-1, VAMP-2) to that of NPTX2 and GluA4 in a large cohort of subjects with DS across the preclinical and clinical AD continuum and explore their correlation with cognitive impairment.MethodsWe quantified the synaptic panel proteins by selected reaction monitoring in CSF from 20 non-trisomic cognitively normal controls (mean age 44) and 80 adults with DS grouped according to clinical AD diagnosis (asymptomatic, prodromal AD or AD dementia). We used regression analyses to determine CSF changes across the AD continuum and explored correlations with age, global cognitive performance (CAMCOG), episodic memory (modified cued-recall test; mCRT) and CSF biomarkers, CSF Aβ42:40ratio, CSF Aβ1-42, CSF p-tau, and CSF NFL. P values were adjusted for multiple testing.ResultsIn adults with DS, VAMP-2 was the only synaptic protein to correlate with episodic memory (delayed recalladj.p= .04) and age (adj.p= .0008) and was the best correlate of CSF Aβ42:40(adj.p= .0001), p-tau (adj.p <.0001), and NFL (adj.p <.0001). Compared to controls, mean VAMP-2 levels were lower in asymptomatic adults with DS only (adj.p= .02). CSF levels of Neurexin-3A, Thy-1, Neurexin-2A, Calysntenin-1, Neuroligin-2, GluA4, and Syntaxin-1B all strongly correlated with NPTX2 (p< .0001), which was the only synaptic protein to show reduced CSF levels in DS at all AD stages compared to controls (adj.p< .002).ConclusionThese data show proof-of-concept for CSF VAMP-2 as a potential marker of synapse degeneration that correlates with CSF AD and axonal degeneration markers and cognitive performance.

Published
2021

30. Una aproximación al tratamiento contable de criptomonedas en el marco de las NIIF.

Author

Luciani Toro, Laura Rosa, Castellanos Sánchez, Heiberg Andrés, Hurtado Briceño, Alberto José, and Zerpa de Hurtado, Sadcidi

Subjects
INTERNATIONAL Financial Reporting Standards, CRYPTOCURRENCIES, SMALL business, INTANGIBLE property, INTERNATIONAL business enterprises, INCORPORATION
Abstract

Copyright of Innovar: Revista de Ciencias Administrativas y Sociales is the property of Universidad Nacional de Colombia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2023
Full Text
View/download PDF

31. Quality of palliative nursing care: Meaning, death anxiety, and the mediating role of well-being.

Author

Zulueta Egea, Mar, Prieto-Ursúa, María, Bermejo Toro, Laura, and Jodar Anchía, Rafa

Abstract

Background: There is increasing concern regarding the quality of palliative nursing care. However, despite the growing number of studies identifying related variables, there is still a paucity of studies analyzing models of how these variables interrelate. Objective: The study aimed to identify the role played in the quality of palliative care of nursing professionals by the variables meaning and death anxiety and to investigate the mediating role of psychological well-being and engagement. Method: 176 palliative nursing professionals participated, selected by non-probabilistic convenience sampling using the snowball method. A simple mediation analysis and a multiple mediator model were performed in parallel, and data were collected using a paper and online questionnaire between January and May 2018. Results: Well-being mediated the impact of meaning (indirect effect = 0.096, SE = 0.044, 95% confidence interval (CI): 0.028, 0.213) and death anxiety (indirect effect = −0.032, SE = 0.013, 95% CI: −0.064, −0.010) on the quality of care. Engagement, on the other hand, only mediated the impact of meaning (indirect effect = 0.185, SE = 0.085, 95% CI: 0.035, 0.372), while the indirect effect of death anxiety with the quality of care through engagement was not statistically significant (indirect effect = 0.008, SE = 0.009, 95% CI: −0.004, 0.032). Significance of results: Death anxiety is not directly related to the quality of care, but rather has an effect through psychological well-being, a variable acting as a mediator between the two. The effect of meaning on the quality of care is explained by the mediation of both engagement and psychological well-being, and its impact on the quality of care is thereby mediated by more variables than death anxiety. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

32. Take charge during treatment: A planned exercise protocol to evaluate disparities and cardiovascular outcomes in Black and White patients with breast cancer undergoing treatment.

Author

Hidde, Mary, primary, Beyer, Andreas M, additional, Beyer, Kirsten M. M., additional, Durand, Matthew J, additional, Phillips, Shane A, additional, Grigoriadis, Georgios, additional, Jankowski, Courtney, additional, Berendt, Madeline, additional, Canales, Bethany, additional, Norwood Toro, Laura, additional, Kong, Amanda L., additional, Hoskins, Kent, additional, Brown, Sherry-Ann, additional, Gutterman, David, additional, and Stolley, Melinda, additional

Published
2022
Full Text
View/download PDF

39. Neural correlates of episodic memory in adults with Down syndrome and Alzheimer's disease

Author

Benejam, Bessy, Aranha, Mateus, Videla Toro, Laura, Padilla, Concepción, Valldeneu, Silvia, Fernández, Susana, Altuna-Azkargorta, Miren, Carmona Iragui, María, Barroeta, Isabel, Iulita, M. Florencia, Montal, Victor, Pegueroles, Jordi, Bejanin, Alexandre, Giménez, Sandra, González-Ortiz, Sofía, Videla, Sebastián, Bartrés-Faz, David, Alcolea, Daniel, Blesa, Rafael, Lleó, Alberto, Fortea, Juan, and Universitat Autònoma de Barcelona

Subjects
Adult, Male, Memory Disorders, Episodic memory, Cognitive Neuroscience, Memory, Episodic, Down syndrome, Middle Aged, Neuropsychological Tests, Alzheimer's disease, Magnetic Resonance Imaging, Cortical thickness, Malaltia d'Alzheimer, Cross-Sectional Studies, Neurology, Alzheimer Disease, Síndrome de Down, Humans, Female, Dementia, Neurology (clinical), Atrophy, Down Syndrome, Alzheimer’s disease, MRI
Abstract

Background Adults with Down syndrome are at an ultra-high risk of developing early-onset Alzheimer’s disease. Episodic memory deficits are one of the earliest signs of the disease, but their association with regional brain atrophy in the population with Down syndrome has not been explored. We aimed to investigate the neuroanatomical correlates of episodic memory in adults with Down syndrome and symptomatic Alzheimer’s disease. Methods Single-center, cross-sectional study. A total of 139 adults with Down syndrome (85 asymptomatic and 54 with symptomatic Alzheimer’s disease) were included in the study (mean age 43.6 ± 10.9 years, 46% female). Episodic memory was assessed using the modified Cued Recall Test. Immediate (trial 1 free immediate recall, trial 3 free immediate recall, total free immediate recall score, and total immediate score) and delayed scores (free delayed recall score and total delayed score) were examined. Cortical thickness from magnetic resonance imaging was determined with surface-based morphometry using the FreeSurfer 6.0 software package. The clusters of reduced cortical thickness were compared between symptomatic and asymptomatic participants to create a cortical atrophy map. Then, the correlation between cortical thickness and the modified Cued Recall Test subscores were separately assessed in symptomatic and asymptomatic subjects, controlling for age, sex, and severity of intellectual disability. Results Compared with asymptomatic participants, those with symptomatic Alzheimer’s disease showed a pattern of cortical atrophy in posterior parieto-temporo-occipital cortices. In symptomatic subjects, trial 1 immediate free recall significantly correlated with cortical atrophy in lateral prefrontal regions. Trial 3 free immediate recall and total free immediate recall were associated with the most widespread cortical atrophy. Total immediate score was related to posterior cortical atrophy, including lateral parietal and temporal cortex, posterior cingulate cortex, precuneus, and medial temporal lobe areas. Delayed memory scores were associated with cortical atrophy in temporoparietal and medial temporal lobe regions. No significant relationships were observed between episodic memory measures and cortical atrophy in asymptomatic subjects. Conclusions Different episodic memory measures were associated with cortical atrophy in specific brain regions in adults with Down syndrome and Alzheimer’s disease. These results overlap with those described in sporadic Alzheimer’s disease and further support the similarities between Down syndrome-associated Alzheimer’s disease and that in the general population.

Published
2022

40. Territorio en sintropía : modelo de gestión para la transición de pequeños productores hacia una economía rural regenerativa. Una mirada desde el ordenamiento territorial y los sistemas de producción agropecuarios. Caso de estudio : Támesis, Antioquia (Colombia)

Author

López Toro, Laura, Gómez-Valencia, Manuela, Muñoz Zorzano, Bernardo, and González-Pérez, María Alejandra

Subjects
Desarrollo rural, DESARROLLO RURAL - COLOMBIA, Regeneración, Tensiones en el uso del suelo, Ruralidad, Ordenamiento territorial rural, Economía rural regenerativa, AGRICULTURA - ASPECTOS SOCIALES, Modelo de gestión, Diseño regenerativo, DESARROLLO ECONÓMICO - ASPECTOS SOCIALES, Támesis (Antioquia, Colombia), ORDENAMIENTO TERRITORIAL
Abstract

Dos desafíos globales están comprometiendo actualmente las posibilidades de supervivencia de la humanidad en la Tierra: la crisis ecosistémica y la crisis de la ruralidad, evidenciadas, por un lado, en el traspaso del umbral de los límites planetarios (pérdida de biodiversidad, cambio climático y desertificación de los suelos, entre otros) y por el otro, en las cifras de inseguridad alimentaria, migración del campo a la ciudad y población rural con Necedidades Básicas Insatisfechas. Frente a este escenario, “Territorio en Sintropía” surge con el propósito de diseñar un modelo de gestión para impulsar la transición de pequeños productores agropecuarios hacia una Economía Rural Regenerativa (ERR), entendida como la aplicación de los patrones y principios de la naturaleza en la construcción de economías rurales capaces de contribuir simultáneamente a la salud de los ecosistemas y de las comunidades rurales por medio de actividades tanto agrícolas como no agrícolas. Elegimos al municipio de Támesis (Antioquia) como caso de estudio, al tratarse de un territorio estratégico, que además de reflejar a nivel local los retos y oportunidades que se observan frente al desarrollo rural desde el ámbito global, nacional y regional, se ha venido posicionando como epicentro de irradiación de un movimiento regenerativo a partir de diferentes iniciativas con perspectiva multiactor impulsadas desde las organizaciones de base, el sector público, el sector privado y la academia., Two global challenges are currently compromising the survival of humanity on Earth: the ecosystem crisis and the crisis of rurality, evidenced, on the one hand, in the crossing of planetary boundaries (loss of biodiversity, climate change and soil desertification, among others) and on the other, in the alarming indicators of food insecurity, migration from the countryside to the city and rural population with unsatisfied basic needs. Under this scenario, “Territory in Syntropy” arises with the purpose of designing a management model to promote the transition of small agricultural producers towards a Regenerative Rural Economy (RRE), understood as the application of the patterns and principles of nature in the construction of rural economies capable of contributing simultaneously to the health of ecosystems and rural communities through both agricultural and non-agricultural activities. We choose Tamesis (Antioquia) as a case study, as it is a strategic territory, which in addition to reflecting at the local level the challenges and opportunities that are observed in rural development from the global, national and regional levels, has been positioning as epicenter of a regenerative movement based on different initiatives with a multi-stakeholder perspective promoted by grassroots organizations, the public sector, the private sector and academia.

Published
2022

41. Supplementary Material for Werden et al. 2021 from Below-ground traits mediate tree survival in a tropical dry forest restoration

Author

Werden, Leland K., Averill, Colin, Crowther, Thomas W., Calderón-Morales, Erick, Toro, Laura, Alvarado J., Pedro, Gutiérrez L., Milena, Mallory, Danielle E., and Powers, Jennifer S.

Abstract

Reforestation is one of our most promising natural climate solutions, and one that addresses the looming biodiversity crisis. Tree planting can catalyse forest community reassembly in degraded landscapes where natural regeneration is slow, however, tree survival rates vary remarkably across projects. Building a trait-based framework for tree survival could streamline species selection in a way that generalizes across ecosystems, thereby increasing the effectiveness of the global restoration movement. We investigated how traits mediated seedling survival in a tropical dry forest restoration, and how traits were coordinated across plant structures. We examined growth and survival of 14 species for 2 years and measured six below-ground and 22 above-ground traits. Species-level survival ranged widely from 7.8% to 90.1%, and a model including growth rate, below-ground traits and their interaction explained more than 73% of this variation. A strong interaction between below-ground traits and growth rate indicated that selecting species with fast growth rates can promote establishment, but this effect was most apparent for species that invest in thick fine roots and deep root structures. Overall, results emphasize the prominent role of below-ground traits in determining early restoration outcomes, and highlight little above- and below-ground trait coordination, providing a path forward for tropical dry forest restoration efforts.This article is part of the theme issue ‘Understanding forest landscape restoration: reinforcing scientific foundations for the UN Decade on Ecosystem Restoration’.

Published
2022
Full Text
View/download PDF

42. Nuestras Voces : Una apuesta pedagógica para la participación en los procesos de aprendizaje de los estudiantes emberas

Author

Garzón Osorio, Martha Lucía, Cartagena Toro, Laura Daniela, Gallego Falla, Stefanía, González Guzmán, Duberney, Oquendo Ríos, Duvan Alberto, Ceballos, Daniel, Martínez Santa, Jefferson, Medina Suárez, Ángela Gabriela, Jáiber Morales Mejía, Rodrigo Grajales, and Educación y Tecnología

Subjects
Relaciones etnicas, 370 - Educación::372 - Educación primaria, Educación intercultural, Grupos etnicos
Abstract

Esta cartilla tiene como propósito compartir con maestros y maestras una serie de actividades que promueven la participación de las niñas y los niños embera en la escuela. Su contenido deriva de la investigación “Perspectivas sobre la participación en los procesos de enseñanza y aprendizaje de los estudiantes embera chamí de dos instituciones educativas urbanas del municipio de Pereira”, financiada por la Vicerrectoría de Investigaciones, Innovación y Extensión de la Universidad Tecnológica de Pereira. Dicha investigación fue ejecutada por los Semilleros de Investigación Diversidad y Educación Inclusiva y Concepciones de Práctica Pedagógica, ambos pertenecientes al Grupo de Investigación Educación y Tecnología de la misma universidad. Proyecto financiado por la Vicerrectoría de Investigaciones de la Universidad Tecnológica de Pereira en el marco de la convocatoria de proyectos de Semilleros de investigación 2020. Vicerrectoria de investigación, innovaión y extensión Universidad Tecnológica de Pereira. Tabla de contenidos Presentación............................................................................................................................................................................. 8 ¿Por qué hablar de participación en el aula?................................................................................................................................. 10 Capítulo 1................................................................................................................................................................................ 12 Las expresiones artísticas mediadoras de interculturalidad....................................................................................................... 12 La participación desde las educación artística.............................................................................................................................. 13 1. Libertad, arte y expresión............................................................................................................................................................ 13 2. La magia del Bastón Jai. ............................................................................................................................................................... 14 3. Ocama: Arte curativo.................................................................................................................................................................... 17 4. Confeccionando interculturalidad y folclor. .............................................................................................................................. 19 5. Brisas y sonidos ............................................................................................................................................................................ 21 6. Cafecito con la Dachi Name......................................................................................................................................................... 23 7. Kipará: Trazos corporales en la otredad.................................................................................................................................... 25 Glosario.......................................................................................................................................................................................... 28 Referencias ................................................................................................................................................................................... 19 Capítulo 2................................................................................................................................................................................ 29 Un mundo que proteger para protegernos .................................................................................................................................. 29 La participación desde las ciencias naturales ............................................................................................................................... 30 1. Conexión natural: un legado cultural para el cuidado animal................................................................................................ 31 2. Animales y relatos................................................................................................................................................................. 32 3. Relatos de la naturaleza............................................................................................................................................................... 34 4. Leyendas que protegen nuestra tierra ...................................................................................................................................... 36 5. Plantas que cuidamos y nos cuidan........................................................................................................................................... 38 Capítulo 3................................................................................................................................................................................ 42 La enseñanza de las ciencias sociales como espacio de participación en el aula y en la sociedad .......... 42 ¿Cómo promover la participación de los estudiantes embera en las prácticas de enseñanza de las ciencias sociales?.... 43 1. Sapo de otro pozo ................................................................................................................................................................. 44 2. Respeto a la diversidad................................................................................................................................................................ 45 3. Mi familia, tu familia, nuestra familia......................................................................................................................................... 46 4. Una línea a través del tiempo ..................................................................................................................................................... 49 5. El caso de Juan ........................................................................................................................................................................ 53 6. El extraterrestre ...................................................................................................................................................................... 56 7. ¿De la Conquista a la barbarie?................................................................................................................................................... 46 Recursos electrónicos................................................................................................................................................................ 49 Referencias ................................................................................................................................................................................... 49 Capítulo 4................................................................................................................................................................................ 60 Literatura y oralidad: del relato común como fuente de participación........................................................................................ 60 1. Los curanderos de Maya la guacamaya..................................................................................................................................... 62 2. La tienda diversa..................................................................................................................................................................... 65 3. Medicina tradicional: entre recetas y saberes .......................................................................................................................... 66 4. Poetas ancestrales................................................................................................................................................................. 68 5. Historiadores de los acervos culturales de las prácticas curativas ancestrales y populares.............................................. 69 Referencias ............................................................................................................................................................................. 74

Published
2022

43. Feasibility and Long-Term Compliance to Continuous Positive Airway Pressure Treatment in Adults With Down Syndrome, a Genetic Form of Alzheimer's Disease

Author

Giménez, Sandra, Farre, Ariadna, Morente, Fátima, Videla Toro, Laura, Gutiérrez, Marta, Clos, Susana, Fernández, Ana, Blanco, Marta, Altuna-Azkargorta, Miren, Pegueroles, Jordi, Asensio, Amparo, Benejam, Bessy, Batista, Mar, Barroeta, Isabel, Fortuna, Ana, Fortea, Juan, Mayos, Mercedes, and Universitat Autònoma de Barcelona

Subjects
General Neuroscience, Down syndrome, Alzheimer's disease, Sleep, Obstructive sleep apnea, CPAP compliance, nervous system diseases, respiratory tract diseases
Abstract

BackgroundDown syndrome (DS) is a genetic form of Alzheimer’s disease (AD) with a high prevalence of obstructive sleep apnea (OSA). These characteristics place the DS population as an optimal model to study the relationship between sleep and AD and to design clinical trials of preventive sleep therapies for AD. Regrettably, OSA treatment with continuous positive airway pressure (CPAP) is often neglected in adults with DS. In both clinical practice and research trials, it is usually presumed that these patients will not adapt to or tolerate the therapy.Study ObjectiveWe aimed to evaluate the feasibility and long-term CPAP compliance in this population and their capacity to be enrolled in CPAP research studies.MethodsWe prospectively compared the CPAP compliance of 17 OSA patients with DS and 19 age and sex matched OSA euploid patients. CPAP management and follow-up schedules were prescribed according to the habitual clinical practice. We compared group differences in tolerance, objective, and subjective hours of nightly CPAP usage at the 1st, 3rd, 6th, 12th, 24th, and 36th month visits. Good compliance was defined as at least 4 h use per night. We also investigated predictive factors of long-term CPAP compliance.ResultsThe percentage of DS subjects with good CPAP compliance (81.2 vs. 78.9%) and the objective CPAP use (5 vs. 6 h, p = 0.92) did not differ from the control group (CG). Subjective CPAP compliance was significantly higher in OSA patients with DS than in controls in all the follow-up visits (8 vs. 6.75 h, p = 0.001). The DS group had a significantly higher number of visits (9 vs. 5; p = 0.021) and mask changes (2.5 vs. 2; p = 0.05) than controls. Objective hours of CPAP use at the first follow-up visit predicted long-term CPAP compliance (p < 0.005).ConclusionCPAP treatment is feasible and has good long-term compliance in OSA patients with DS. It should be recommended to improve health and prevent comorbidities. The DS population is indeed suitable to participate in longitudinal preventive sleep clinical trials for AD.

Published
2022

45. Phosphorus limitation of early growth differs between nitrogen‐fixing and nonfixing dry tropical forest tree species.

Author

Toro, Laura, Pereira‐Arias, Damaris, Perez‐Aviles, Daniel, Vargas G., German, Soper, Fiona M., Gutknecht, Jessica, and Powers, Jennifer S.

Subjects
*TROPICAL dry forests, *FOREST succession, *FOREST dynamics, *TROPICAL forests, *SPECIES, *CARBON nanofibers
Abstract

Summary: Tropical forests are often characterized by low soil phosphorus (P) availability, suggesting that P limits plant performance. However, how seedlings from different functional types respond to soil P availability is poorly known but important for understanding and modeling forest dynamics under changing environmental conditions.We grew four nitrogen (N)‐fixing Fabaceae and seven diverse non‐N‐fixing tropical dry forest tree species in a shade house under three P fertilization treatments and evaluated carbon (C) allocation responses, P demand, P‐use, investment in P acquisition traits, and correlations among P acquisition traits.Nitrogen fixers grew larger with increasing P addition in contrast to non‐N fixers, which showed fewer responses in C allocation and P use. Foliar P increased with P addition for both functional types, while P acquisition strategies did not vary among treatments but differed between functional types, with N fixers showing higher root phosphatase activity (RPA) than nonfixers.Growth responses suggest that N fixers are limited by P, but nonfixers may be limited by other resources. However, regardless of limitation, P acquisition traits such as mycorrhizal colonization and RPA were nonplastic across a steep P gradient. Differential limitation among plant functional types has implications for forest succession and earth system models. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

46. Below-ground traits mediate tree survival in a tropical dry forest restoration.

Author

Werden, Leland K., Averill, Colin, Crowther, Thomas W., Calderón-Morales, Erick, Toro, Laura, J., Pedro Alvarado, L., Milena Gutiérrez, Mallory, Danielle E., and Powers, Jennifer S.

Abstract

Reforestation is one of our most promising natural climate solutions, and one that addresses the looming biodiversity crisis. Tree planting can catalyse forest community reassembly in degraded landscapes where natural regeneration is slow, however, tree survival rates vary remarkably across projects. Building a trait-based framework for tree survival could streamline species selection in a way that generalizes across ecosystems, thereby increasing the effectiveness of the global restoration movement. We investigated how traits mediated seedling survival in a tropical dry forest restoration, and how traits were coordinated across plant structures. We examined growth and survival of 14 species for 2 years and measured six below-ground and 22 above-ground traits. Species-level survival ranged widely from 7.8% to 90.1%, and a model including growth rate, below-ground traits and their interaction explained more than 73% of this variation. A strong interaction between below-ground traits and growth rate indicated that selecting species with fast growth rates can promote establishment, but this effect was most apparent for species that invest in thick fine roots and deep root structures. Overall, results emphasize the prominent role of below-ground traits in determining early restoration outcomes, and highlight little above- and below-ground trait coordination, providing a path forward for tropical dry forest restoration efforts. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

47. PLAN DE INCORPORACIÓN DE APPS GRATUITAS EN LÍNEA. CASO DE LAS MIPYME CAMARONERAS Y BANANERAS EN LA PROVINCIA DE EL ORO, ECUADOR.

Author

Luciani Toro, Laura Rosa, Zerpa de Hurtado, Sadcidi, Hurtado Briceño, Alberto José, and Castellanos Sánchez, Heiberg Andrés

Subjects
INFORMATION & communication technologies, APPLICATION software, INFORMATION storage & retrieval systems, SMALL business
Abstract

Copyright of Agroalimentaria is the property of Alejandro Antonio Gutierrez Socorro and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2023
Full Text
View/download PDF

49. Nuestras voces

Author

Garzón Osorio, Martha Lucía, primary, Cartagena Toro, Laura Daniela, additional, Gallego Falla, Stefanía, additional, González Guzmán, Duberney, additional, Oquendo Ríos, Duvan Alberto, additional, Ceballos, Daniel, additional, Martínez Santa, Jefferson, additional, and Medina Suárez, Ángela Gabriela, additional

Published
2022
Full Text
View/download PDF

50. Differential levels of Neurofilament Light protein in cerebrospinal fluid in patients with a wide range of neurodegenerative disorders

Author

Delaby, Constance, Alcolea, Daniel, Carmona Iragui, María, Illán-Gala, Ignacio, Morenas Rodríguez, Estrella, Barroeta, Isabel, Altuna-Azkargorta, Miren, Estellés, T., Santos-Santos, M., Turon-Sans, J., Muñoz, L., Ribosa-Nogué, Roser, Sala-Matavera, I., Sánchez-Saudinós, María Belén, Subirana, A., Videla Toro, Laura, Benejam, Bessy, Sirisi Dolcet, Sonia, Lehmann, S., Belbin, Olivia, Clarimón, Jordi, Blesa, Rafael, Pagonabarraga Mora, Javier, Rojas-Garcia, Ricard, Fortea, Juan, Lleó, Alberto, Universitat Autònoma de Barcelona, Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Cellules Souches, Plasticité Cellulaire, Médecine Régénératrice et Immunothérapies (IRMB), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona (UAB), Centro de Investigacion Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III [Madrid] (ISC), German Research Center for Neurodegenerative Diseases - Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Ludwig-Maximilians-Universität München (LMU), CIBER de Enfermedades Raras (CIBERER), and Salvy-Córdoba, Nathalie

Subjects
0301 basic medicine, Male, Pathology, Neurology, [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, MESH: Neurodegenerative Diseases, Cohort Studies, 0302 clinical medicine, Cerebrospinal fluid, Neurofilament Proteins, MESH: Early Diagnosis, Medicine, Amyotrophic lateral sclerosis, MESH: Neurofilament Proteins, MESH: Cohort Studies, [SDV.BBM.BC] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], MESH: Aged, Multidisciplinary, Neurodegeneration, Neurodegenerative Diseases, MESH: Follow-Up Studies, Disease Progression, Female, MESH: Disease Progression, Alzheimer's disease, Frontotemporal dementia, medicine.medical_specialty, Science, Neuroaxonal Dystrophies, Article, Progressive supranuclear palsy, 03 medical and health sciences, mental disorders, Humans, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], Aged, MESH: Humans, business.industry, Dementia with Lewy bodies, [SDV.NEU.NB] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, medicine.disease, MESH: Neuroaxonal Dystrophies, MESH: Male, 030104 developmental biology, Early Diagnosis, MESH: Biomarkers, business, MESH: Female, 030217 neurology & neurosurgery, Biomarkers, Follow-Up Studies
Abstract

Altres ajuts: "Marató TV3" grant (20141210, 044412, 20143710). Cerebrospinal fluid (CSF) biomarkers are useful in the diagnosis and the prediction of progression of several neurodegenerative diseases. Among them, CSF neurofilament light (NfL) protein has particular interest, as its levels reflect neuroaxonal degeneration, a common feature in various neurodegenerative diseases. In the present study, we analyzed NfL levels in the CSF of 535 participants of the SPIN (Sant Pau Initiative on Neurodegeneration) cohort including cognitively normal participants, patients with Alzheimer disease (AD), Down syndrome (DS), frontotemporal dementia (FTD), amyotrophic lateral sclerosis (ALS), dementia with Lewy bodies (DLB), progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS). We evaluated the differences in CSF NfL accross groups and its association with other CSF biomarkers and with cognitive scales. All neurogenerative diseases showed increased levels of CSF NfL, with the highest levels in patients with ALS, FTD, CBS and PSP. Furthermore, we found an association of CSF NfL levels with cognitive impairment in patients within the AD and FTD spectrum and with AD pathology in DLB and DS patients. These results have implications for the use of NfL as a marker in neurodegenerative diseases.

Published
2020

Catalog

Books, media, physical & digital resources
See catalog results