21 results on '"Topak, Osman Zülkif"'
Search Results
2. Effects of Selective Serotonin Reuptake Inhibitor Treatment on Ovarian Reserves in Patients with Depression
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Gök, Soner, primary, Gök, Berfin Can, additional, Alataş, Erkan, additional, Senol, Hande, additional, and Topak, Osman Zülkif, additional
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- 2023
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3. Cognitive outcomes of transcranial magnetic stimulation in treatment-resistant depression: a randomized controlled study
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YILDIZ, TAHİR, primary, OĞUZHANOĞLU, NALAN KALKAN, additional, and TOPAK, OSMAN ZÜLKİF, additional
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- 2023
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4. Koroner arter bypass greft cerrahisinde hastalara işlem hakkında sözel-görsel bilgilendirme yapmak psikolojik fonksiyonlar açısından önemli midir?
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Topak, Osman Zülkif, Baltalarlı, Ahmet, Önem, Gökhan, and Özdel, Osman İsmail
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Psychiatry ,Koroner arter bypass greft ameliyatı,yeti yitimi,başetme becerileri,yaşam kalitesi ,coronary artery bypass grafting surgery,disability,coping skills,quality of life ,Psikiyatri - Abstract
Purpose: Being well informed can help with developing strategies to cope, can contribute to the psychological well-being of patients and improve their quality of life. It is aimed to investigate the effect of verbal-visual information compared to only written information before the procedure on coping methods, quality of life and disability in patients who will undergo coronary artery bypass surgery. Materials and methods: Forty-eight patients were divided into two equal groups. While the first group was informed about the risks of the operation process and postoperative care verbally and visually, the other group was given only written information. All patients underwent standardized psychiatric interviews according to DSM V, before and after surgery The Brief Disability Questionnaire (BDQ), Coping Scale (COPE), Hospital Anxiety and Depression Scale (HADS), Health Related Quality of life Short-Form 36 (HRQOL-BRIEF SF-36) was applied.Results: Although psychiatric disorders are more common in women than men, no statistical difference was found. It was observed that the most common diagnosis was adjustment disorder. Although there was no significant difference between the groups in terms of anxiety and depressive symptoms and quality of life, it was observed that the use of religious coping decreased and disability increased after surgery only in the written-informed group. Further, disability scores were positively correlated with the endpoint depression and anxiety scores in the group given only written information.Conclusion: Being well-informed verbally and visually about the surgery process positively affects patients’ coping strategies and adjustment while decreasing psychiatric comorbidity and disability rates. Further longitudinal research is recommended in various cultures to identify patients’ modifiable risk factors in terms of psychological outcomes., Amaç: İyi bilgilendirilmiş olmak, başa çıkma stratejileri geliştirmeye yardımcı olabilir, hastaların psikolojik iyilik hallerine katkıda bulunabilir ve yaşam kalitelerini iyileştirebilir. Bu çalışmada koroner arter by-pass cerrahisi yapılacak hastalarda işlem öncesi sözel-görsel bilgilendirme yapılmasının sadece yazılı bilgilendirme yapılmasına kıyasla hayat kalitesi, yeti yitimi ve başetme yöntemleri üzerine nasıl bir etkisinin olacağının araştırılması amaçlanmıştır.Gereç ve yöntem: Çalışmamıza 48 hasta alınmış ve hastalar iki eşit gruba bölünmüştür. Birinci gruba, ameliyat süreci ve olası riskler ayrıntılı bir şekilde sözel-görsel olarak anlatılmış, ikinci grup ise yalnızca yazılı olarak bilgilendirilmiştir. Tüm hastalara DSM V’e göre standardize psikiyatrik görüşme yapılmış, ameliyat öncesinde ve sonrasında Kısa Yeti Yitimi Anketi (KYA), Başa Çıkma Tutumlarını Değerlendirme Ölçeği (COPE), Hastane Anksiyete ve Depresyon Ölçeği (HAD), Kısa form 36 Yaşam Kalitesi Ölçeği (SF-36) uygulanmıştır. Bulgular: Psikiyatrik bozukluklar genel olarak kadınlarda erkeklere göre daha fazla olmakla birlikte istatiksel fark saptanmamıştır. En sık konulan tanının, uyum bozukluğu olduğu gözlenmiştir. Gruplar arasında anksiyete ve depresif semptomlar ile yaşam kalitesi açısından anlamlı fark saptanmamasına ragmen, yalnızca yazılı olarak bilgilendirilmiş grupta ameliyat sonrası dini olarak başa çıkma kullanımının azaldığı ve yeti yitiminin arttığı gözlenmiştir. Ayrıca, yazılı bilgilendirilmiş grupta depresyon ve anksiyete puanları ile yeti yitimi arasında pozitif yönde korelasyon olduğu saptandı.Sonuç: Ameliyat hakkında ayrıntılı sözel-görsel bilgilendirme yapılması hastaların ameliyat sonrası süreçte başetme stratejilerini etkilemekte ve daha sağlıklı bir şekilde uyum sağlamalarına yardımcı olarak yeti yitimini azaltmaktadır. Ameliyat sonrası dönemde hastaların psikolojik fonksiyonlarını etkileyebilecek modifiye edilebilir risk faktörlerinin de belirlenmesi açısından farklı kültürlerde uzun dönem çalışmalara ihtiyaç duyulmaktadır.
- Published
- 2022
5. In coronary artery bypass grafting surgery, is it important to give patients verbal-visual information about the operation to improve their psychological functions?
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TOPAK, Osman Zülkif, primary, BALTALARLI, Ahmet, additional, ÖNEM, Gökhan, additional, and ÖZDEL, Osman, additional
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- 2022
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6. Is it important to give patients verbal-visual information about the operation to improve their psychological functions in coronary artery bypass graft surgery?
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Topak, Osman Zülkif, Baltalarlı, Ahmet, Önem, Gökhan, and Özdel, Osman İsmail
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CORONARY artery bypass ,PSYCHOLOGICAL well-being ,QUALITY of life ,MENTAL illness ,POSTOPERATIVE period - Abstract
Copyright of Pamukkale Medical Journal is the property of Pamukkale Journal of Medicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2022
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- View/download PDF
7. Theory of mind and executive functions in bipolar disorder patients and their first-degree relatives (tur)
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Duman, Taçlan, primary, Ateşçi, Figen, additional, Topak, Osman Zülkif, additional, Şendur, İbrahim, additional, Tümkaya, Selim, additional, and Özdel, Osman, additional
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- 2019
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8. Şizofrenili ve şizoaffektif bozukluklu hasta lenfositlerinde dna hasarı ve tamir etkinliğindeki farklılıkların değerlendirilmesi
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Topak, Osman Zülkif, Özdel, Osman İsmail, and Ruh Sağlığı ve Hastalıkları Anabilim Dalı
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Psychiatry ,Psychotic disorders ,Schizophrenia ,DNA damage ,DNA repair ,Lymphocytes ,DNA ,Psikiyatri ,Affective disorders - Abstract
Şizofreni ve şizoaffektif bozukluk, kronik, ciddi yeti yitimine neden olan psikiyatrik bozukluklardır. Son dönemde çalışmalar şizofreni ve şizoaffektif bozukluğun oluş mekanizması, semptomatolojileri ve tedavilerindeki farklılıklara odaklanmıştır. Çalışmamızın amacı şizofreni ve şizoaffektif bozukluğun patofizyolojisinde oksidatif hasarın, onarım mekanizmalarının ve kullanılan ilaçların DNA hasarına katkılarının rolünü ortaya koymaktır. Çalışmamıza DSM 5'e göre tanı konmuş 18-60 yaş arası, fiziksel ve nörolojik hastalığı olmayan, mental kapasitesi olağan, okuma yazma bilen ve en az 5 yıldır tanı konmuş 30 şizofreni, 30 şizoaffektif bozukluklu hasta ve 30 sağlıklı gönüllü katılmıştır. Hastalara gruplarına göre hastalığın seyrini ve şiddetini değerlendirme amacıyla ölçekler uygulanmıştır. Tüm katılımcılardan 5ml kan alınarak lenfositlerde commet assay yöntemiyle DNA hasarı; ELİSA ile TAS, TOS ve OSİ değerleri; gerçek zamanlı PCR ile OGG1 ve NEIL1 gen ekspresyonları ölçülmüştür. Ayrıca in vitro assay yöntemi ile ilaçların DNA hasarına etkisine bakılmıştr. Çalışmamızda Şizofreni hastalarında Şizoaffektif ve kontrol grubuna oranla DNA hasarı yüksek çıkmıştır. Şizoaffektif hastalarda şizofrenlere göre oksidatif stres oranı düşük çıkmış, OGG1 gen expresyonu da yüksek bulunmuştur. Paliperidon, klozapin ve valproik asit kullanan hastalarda DNA hasarının düşük olduğu bulunmuş, yapılan in vitro analizlerde de ilaçların DNA hasarına neden olmadığı görülmüştür. Sonuç olarak Şizofrenili hastalarda Şizoaffektiflere oranla DNA hasarının yüksek olduğu, bu durumun hem şizoaffektif hastaların daha az oksidatif hasara maruz kalmasından hem de onarım süreçlerinin daha çok çalışmasından kaynaklandığı görülmüştür. Aynı zamanda ilaçların DNA hasarına yol açmadığı, bazılarının DNA hasarını azalttığı görülmüştür. Çalışmamız bu hastalıkların hastalığın seyri, hastaların tedavi ihtiyaçları ve takip sıklıklarının planlanabilmesi açısından ayrı ayrı değerlendirilmesi gerektiğini göstermektedir. Schizophrenia and schizoaffective disorder are chronic psychiatric disorders that cause severe disability. Recent studies have focused on the pathophysiology, symptomatology and differences in treatments of schizophrenia and schizoaffective disorder. The aim of the study is to demonstrate the role of oxidative damage and repair mechanisms in pathophysiology of schizophrenia and schizoaffective disorder, and the contribution of drugs to DNA damage. 30 schizophrenic and 30 schizoaffective patients diagnosed according to DSM V and having at least 5 years of disease history, aged between 18 and 60, with no physical and neurological disease, normal mental capacity and literate and 30 healthy volunteers having similar features were participated in the study. Scales were applied to assess the course and severity of the disease ındividually by groups. 5ml blood was taken from all participants and DNA damage was measured in lymphocytes using the commet assay method; TAS, TOS, OSI were by ELISA and OGG1, NEIL1 gene expressions by real-time PCR and the effect of drugs on DNA damage by in vitro assay. The results showed that DNA damage was higher in Schizophrenia patients than in Schizoaffective and control group. The rate of oxidative stress was lower in schizoaffective patients than schizophrenic patients, and the OGG1 gene expression was also found to be high in schizoaffective patients. DNA damage was found lower in patients using paliperidone, clozapine, and valproic acid. In-vitro analysis also showed that the drugs did not cause DNA damage. As a result, DNA damage was higher in schizophrenic patients compared to schizoaffective disorders, and this had been attributed to the both less exposure of oxidative damage and to the more work of the repair processes in schizoaffective patients. Therewithal, drugs did not cause DNA damage, and some of them seemed to reduce DNA damage. As a result, these diseases should be evaluated separately in order to anticipate disease progression, and to plan treatment strategies of patients and frequency of control examination. 136
- Published
- 2017
9. Poster Presentations
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Önder, Arif, primary, Adanır, Aslı Sürer, additional, Bilaç, Öznur, additional, Kavurma, Canem, additional, Doğan, Yakup, additional, Sapmaz, Şermin Yalın, additional, Türkmen, Nurcan Bektaş, additional, Tekeş, Feyza Alyu, additional, Arslan, Rana, additional, Kurtses Gürsoy, Betül, additional, Öztürk, Büşra, additional, Işıldar, Yetiş, additional, Uzunoğlu, Gülçin Bölük, additional, Bilgen, Nuran, additional, Doğan, Bilge, additional, Duman, Ali, additional, Memiş, Çağdaş Öykü, additional, Kocabaş, Oktay, additional, Sevinçok, Levent, additional, Üçel, Umut İrfan, additional, Demir Özkay, Ümide, additional, Can, Özgür Devrim, additional, Akpınar, Kemal, additional, Özdel, Osman İsmail, additional, Bora, Sultan Taş, additional, Buldukoğlu, Kadriye, additional, Karatoprak, Serdar, additional, Dönmez, Yunus Emre, additional, Özcan, Özlem, additional, Altun, Hatice, additional, Altun, İdiris, additional, Ardic, Ferhat Can, additional, Kose, Samet, additional, Solmaz, Mustafa, additional, Kulacaoglu, Filiz, additional, Balcioglu, Yasin Hasan, additional, Olğar, Yusuf, additional, Turan, Belma, additional, Öztürk, Yusuf, additional, Gelegen, Volkan, additional, Tamam, Lut, additional, Aslan, Şerife, additional, Çamlı, Nevzat, additional, Topak, Osman Zülkif, additional, Tümkaya, Selim, additional, Ateşci, Figen Çulha, additional, Metin, Ozge, additional, Ray, Perihan Cam, additional, Kaypakli, Gamze Yapca, additional, Eynalli, Ezgi, additional, Tahiroglu, Aysegul Yolga, additional, Karci, Canan Kuygun, additional, Celik, Gonca Gul, additional, Çimik, Alper, additional, Alyu, Feyza, additional, Zıblak, Alper, additional, Kenar, Ayşe Nur İnci, additional, Yücel, Nazlı Turan, additional, Barbaros, Mustafa Burak, additional, Eker, Dilan, additional, Çimen, Esen, additional, Gündoğmuş, İbrahim, additional, Algül, Ayhan, additional, Karagöz, Abdulkadir, additional, Kıyançiçek, Murat, additional, Kalcı, Pelin, additional, Karaş, Hakan, additional, Polat, Aslıhan, additional, Alğan, Zehra, additional, İbiloğlu, Aslıhan Okan, additional, İbiloglu, İbrahim, additional, Aslaner, Dilek, additional, Comlekci, Mevlut, additional, Sagir, Selim, additional, Basoglu, Tuba, additional, Özen, Murat Eren, additional, Örüm, Mehmet Hamdi, additional, Kalenderoğlu, Aysun, additional, Peltek, Gülümser, additional, Selek, Salih, additional, Atmaca, Murad, additional, Vural, Mehmet, additional, Aydın, Halef, additional, Yılmaz, Sedat, additional, Öner, Ramazan İlyas, additional, Karadağ, Ayşe Sevgi, additional, Kara, Mahmut Zabit, additional, Usta, Miraç Barış, additional, Karabekiroğlu, Koray, additional, Şahin, Berkan, additional, Aydın, Muazzez, additional, Bozkurt, Abdullah, additional, Karaosman, Tolga, additional, Aral, Armağan, additional, Çobanoğlu, Cansu, additional, Kurt, Ayşegül Duman, additional, Kesim, Neriman, additional, Şahin, İrem, additional, Ürer, Emre, additional, Eğilmez, Oğuzhan Bekir, additional, Utkan, Tijen, additional, Sahin, Tugce Demirtas, additional, Gocmez, Semil Selcen, additional, Yazir, Yusufhan, additional, Aricioglu, Feyza, additional, Yurtdaş, Cangül, additional, Zortul, Hacer, additional, Yilmaz, Bayram, additional, Arıcıoğlu, Feyza, additional, Parlaktaş, Hatice Kübra, additional, Uçar, Aylin Yaba, additional, Yılmaz, Bayram, additional, Kurtul, Neslihan, additional, Arıcı, Asiye, additional, Yazar, Ece Merve, additional, Uzun, Necati, additional, Akça, Ömer Faruk, additional, Kılınç, İbrahim, additional, Balcı, Tevfik, additional, Bayru, Ozge, additional, Bertizlioğlu, Osman, additional, Yalçın, Funda Yiğit, additional, Bolu, Abdullah, additional, Akar, Hatice, additional, Aydın, Mehmet Sinan, additional, Doruk, Ali, additional, Mutu, Tuğba, additional, Yazici, Esra, additional, Guzel, Derya, additional, Erol, Atila, additional, Çiftçi, Elvan, additional, Kaya, Heysem, additional, Güleç, Hüseyin, additional, Salah, Albert Ali, additional, Kalyoncu, Tuğba, additional, Çıldır, Deniz Argüz, additional, Ergüvendi, Fazilet, additional, Shamkhalova, Ulkar, additional, Gok, Ezgi Eynallı, additional, Altunbasak, Sakir, additional, Dogankoc, Seyda Besen, additional, Ovetti, Nefise Hilal Cansever, additional, Metin, Özge, additional, and Shamkhalova, Ulkhar, additional
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- 2018
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10. Anksiyete bozukluklarının tedavisi
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Topak, Osman Zülkif and Özdel, Osman İsmail
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- 2016
11. Yaşlılık Dönemi Depresyonunda Apatinin Depresif Belirti Şiddeti ve Bilişsel İşlevlerle İlişkisi.
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SÖZERİ-VARMA, Gülfizar, BİNGÖL, Ceren, TOPAK, Osman Zülkif, ENLİ, Yaşar, and ÖZDEL, Osman
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APATHY ,COGNITION in old age ,MENTAL depression ,INTERVIEWING ,RESEARCH methodology ,MENTAL illness ,MENTAL orientation ,SPACE perception ,SEVERITY of illness index ,OLD age - Abstract
Copyright of Archives of Neuropsychiatry / Nöropsikiyatri Arşivi is the property of Turkish Association of Neuropsychiatry and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2019
12. DSM-5 Bozuklukları için Yapılandırılmış Klinik Görüşmenin Klinisyen Versiyonunun Türkçeye Uyarlanması ve Güvenilirlik Çalışması.
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ELBİR, Müge, ALP TOPBAŞ, Özge, BAYAD, Serkan, KOCABAŞ, Tuğba, TOPAK, Osman Zülkif, ÇETİN, Şahabettin, ÖZDEL, Osman, ATEŞÇİ, Figen, and AYDEMİR, Ömer
- Abstract
Copyright of Turk Psikiyatri Dergisi is the property of Turk Psikiyatri Dergisi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2019
- Full Text
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13. Şizofreni ve Şizoaffektif Bozuklukta Klinik İçgörü İşleyen Bellek Bileşenleri ile İlişkili midir?
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TÜMKAYA, Selim, HANCI YENİGÜN, Ezgi, TOPAK, Osman Zülkif, ŞENDUR, İbrahim, ÖZTÜRK ATKAYA, Neşe, and ÖZDEL, Osman
- Abstract
Copyright of Turk Psikiyatri Dergisi is the property of Turk Psikiyatri Dergisi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2019
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14. Adaptation and Reliability of the Structured Clinical Interview for DSM-5-Disorders - Clinician Version (SCID-5/CV) to the Turkish Language.
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ELBİR, Müge, ALP TOPBAŞ, Özge, BAYAD, Serkan, KOCABAŞ, Tuğba, TOPAK, Osman Zülkif, ÇETİN, Şahabettin, ÖZDEL, Osman, ATEŞÇİ, Figen, and AYDEMİR, Ömer
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BLAND-Altman plot ,CLASSIFICATION of mental disorders ,TURKISH language ,SOCIAL anxiety ,ATTENTION-deficit hyperactivity disorder ,OBSESSIVE-compulsive disorder ,PANIC disorders - Abstract
Objective: In this study, we aimed to adapt the Structured Clinical Interview for DSM-5-ClinicianVersion into Turkish and to demonstrate its reliability. Method: A total of 185 patients, both inpatient and outpatient, from two different university hospitals were included. Training sessions on the features and use of SCID-5/CV were held before the data collection. During the study, in order to test the diagnostic agreement and accuracy, two psychiatrists remained present at the evaluation of each participant; alternatively being interviewer and the observer. Cohen's kappa coefficient for inter-rater reliability was calculated for every diagnostic category. Results: The patient group had a mean age of 37.2 (±13.5) years and 55.7% were female. The education status was as follows: 2.7% were illiterate, 1.7% literate with no primary education, 33% had primary education, 23.8% had secondary education and 38.9% had higher education. The calculated kappa value showed excellent agreement for schizophrenia (κ=0.93), bipolar disorder (κ=0.96), major depressive disorder (κ=0.89), dysthymic disorder (κ=0.82), alcohol use disorder (κ=0.96), panic disorder (κ=0.84), agoraphobia (κ=0.85), social anxiety disorder (κ=0.95), generalized anxiety disorder (κ=0.89), obsessive compulsive disorder (κ=0.87), posttraumatic stress disorder (κ=0.89), adult attention deficit and hyperactivity disorder (κ=1.00), specific phobias (κ=0.82) and very good agreement with adjustment disorder (κ=0.78) and somatic symptom disorder (κ=0.65). Conclusion: Similar to the past SCID versions, kappa values were found to be quite high and all were statistically significant. The Turkish version of SCID-5/ CV can be reliably used in both clinical practice and clinical studies. [ABSTRACT FROM AUTHOR]
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- 2019
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15. Is Clinical Insight Associated with Working Memory Components in Schizophrenia and Schizoaffective Disorder?
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TÜMKAYA, Selim, HANCI YENİGÜN, Ezgi, TOPAK, Osman Zülkif, ŞENDUR, İbrahim, ÖZTÜRK ATKAYA, Neşe, and ÖZDEL, Osman
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SHORT-term memory ,SCHIZOAFFECTIVE disorders ,INFORMATION retrieval ,SITUATIONAL awareness ,ELECTRON work function ,PEOPLE with schizophrenia - Abstract
Objective: Previous studies suggest that the level of clinical insight in schizophrenia patients is related to working memory functions. However, these studies were not specifically concerned with the components of working memory and had not focused in detail on working memory functions. For this reason, the current study investigated the relationship between clinical insight and working memory components in patients with schizophrenia and schizoaffective disorder. Method: The patient group was evaluated by using the Scale for Assessment of Negative Symptoms, the Scale for Assessment of Positive Symptoms, and the Scale to Assess Unawareness of Mental Disorder to measure clinical insight. Moreover, all participants underwent a "Situation Awareness" test in order to measure working memory functions. Based on published data, the first stage of this test was accepted to measure the "visual spatial sketchpad" component of working memory, and the second stage was accepted to measure the "episodic buffer" (bound information storage) component. The functions of these components were measured separately as top-down and bottom-up cognitive processes. Results: The episodic buffer function (managed by the bottom-up cognitive process) was related with clinical insight. This relationship also continued after correcting for the effect of positive symptoms on insight. The patients performed worse than the controls in terms of visual spatial sketchpad function, which was managed by both top-down and bottom-up cognitive processes. The patients performed worse than the controls in terms of both top-down and bottom-up cognitive processes and visual spatial sketchpad function. Furthermore, the patients were also worse than the controls in terms of episodic buffer function (managed by top-down cognitive processes). Conclusion: Clinical insight may be associated with binding function (associated with episodic buffer function) managed by bottom-up cognitive processes in patients with schizophrenia and schizoaffective disorder. Further studies are necessary to confirm this novel finding. [ABSTRACT FROM AUTHOR]
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- 2019
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16. Bir Grup Tıp Fakültesi Öğrencisinde Öğrenim Sürecinde Tükenmişlik Düzeylerinin Karşılaştırılması: Tıp Eğitim Süreci Tükenmişlik Düzeylerini Değiştiriyor mu?
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Topak, Osman Zülkif, Karan, Cevriye Beyza, Toktaş, Selma Nur, Gündoğmuş, Safiye Zuhal, and Özdel, Osman
- Abstract
Amaç: Bu araştırmanın amacı, Tıp fakültesi birinci sınıf öğrencileri ile altıncı sınıf öğrencilerini tükenmişlik riski açısından karşılaştırmak, uzun ve zorlu bir süreç olan tıp eğitiminin ve ilk kez hasta-hekim ilişkisinin yaşandığı son sınıf yıllarının tükenmişlik gelişimine olan etkisinive bunun kişilik özellikleriyle bağlantısı olup olmadığını ortaya koymaktır. Yöntem: Tıp Fakültesi Dönem 1 öğrencilerinden 30 ve Dönem 6 öğrencilerinden 30 olmak üzere onam veren toplam 60 öğrenci çalışmaya dâhil edildi.Tüm katılımcıların sosyodemografik bilgileri alınarak, her birine Maslach Tükenmişlik Envanteriile A Tipi Davranış Testi uygulandı. Bulgular: Dönem 6 öğrencilerinin Maslach Tükenmişlik Envanteri duygusal tükenmişlik alt ölçeği ortalaması Dönem 1 öğrencilerinden yüksekti. Kişilik davranışı açısından iki grup karşılaştırıldığında; A ve B tipi kişilik davranışı dağılımının iki g r u p t a da benzer olduğu belirlendi. Sonuç: Bu çalışmada, yapılan diğer çalışmalarla benzer olarak son sınıf öğrencilerinde tükenmişlik düzeyi artmaktadır. Bizim çalışmamızda, son sınıf intörn öğrencilerinde A tipi kişilik sayıca fazla bulunsa da bu fazlalık istatiksel olarak anlamlı düzeye ulaşmamıştır. Ayrıca kişilik tipi ile tükenmişlik düzeyi ve kişisel başarı duygusu arasında herhangi biristatistiksel ilişki d e izlenmemiştir. Objectives: The aim of this study was to investigate the differences of the risk of burnout in medical students between the first year and last year which students first experience both physician-patient relationship and so long, so challenging medical course process. Method: A cross-sectional study was carried out in a sample of 60 medical students which were randomly selected and gave informed consent. Thirty students (50%) were in the first year and 30 were (50%) in the sixth year of training using sociodemographic data form, Maslach Burn out Inventory and A type personality test. Results: Maslach Burnout Ýnventory emotional exhaustion subscale was higher at last year medical students than the first year students. About personality behaviour; when two groups compared, no significant differenceswere found in each groups. Conclusion:In this study, burnout levels was higher at the last year medical students as previous studies had done before. In our study, although type A characteristics were numerously higher, it was not significant statically. Further more we did not find any relationship between personality characteristics in terms of type A and type B and burnout levels or sense of personel accomplishment. [ABSTRACT FROM AUTHOR]
- Published
- 2015
17. Bipolar bozukluk hastaları ve birinci derece yakınlarında zihin kuramı ve yürütücü işlevler.
- Author
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Duman, Taçlan, Ateşçi, Figen, Topak, Osman Zülkif, Şendur, İbrahim, Tümkaya, Selim, and Özdel, Osman
- Abstract
Objective: In this study it is aimed to compare the theory of mind skills and executive functions in bipolar disorder patients and their first degree relatives with controls, and to demonstrate the relationship between executive functions and theory of mind. Method: 30 patients with euthymic bipolar I disorder, their first degree relatives, and 30 healthy controls were included in the study. Sociodemographic data form, Hamilton Depression Rating Scale, Young Mania Rating Scale, Wechsler Adults Intelligence Test were applied to all participants; Wisconsin Card Sorting Test, Stroop Test, Trail Making Test A and B, and Digit Span Test were applied to evaluate the executive functions; Reading the Mind in the Eyes Test, Hinting Task and Faux Pas Test were applied to evaluate the theory of mind skills. Results: There was not any significant difference between the groups in terms of theory of mind, although total scores were seen from bad to good in bipolar patients, first degree relatives and controls respectively. Patient group had significantly lower performance in Trail Making Test A, and DigitSpan Test inverse number scores. As the severity of disease increased, cognitive functions and the theory of mind were seen to be worsened. The theory of mind was related to executive functions. Discussion: In conclusion, we did not find significant losses in terms of theory of mind in bipolar patients and their first degree relatives. But bipolar patients had a deficiency in attention, psychomotor speed and verbal working memory; and theory of mind was related to executive functions. [ABSTRACT FROM AUTHOR]
- Published
- 2019
- Full Text
- View/download PDF
18. Cognitive outcomes of transcranial magnetic stimulation in treatment-resistant depression: a randomized controlled study.
- Author
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Yıldız T, Oğuzhanoğlu NK, and Topak OZ
- Subjects
- Humans, Transcranial Magnetic Stimulation methods, Depression, Psychiatric Status Rating Scales, Treatment Outcome, Double-Blind Method, Cognition, Depressive Disorder, Major therapy, Depressive Disorder, Treatment-Resistant therapy, Depressive Disorder, Treatment-Resistant psychology
- Abstract
Background: Major depressive disorder (MDD) is a significant cause of workforce loss, and is associated with cognitive impairments which can continue even after the elimination of mood and behavioural symptoms. The aim of this study was to investigate the benefit of transcranial magnetic stimulation (TMS) on cognitive functions in treatment resistant depression., Methods: This randomised controlled clinical trial was conducted at a university hospital, department of psychiatry (tertiary centre) between October 2019 and July 2020. The study included 30 patients with depressive disorder, aged 18-50 years, who did not respond to at least two antidepressant medications for at least 8 weeks (one drug used was serotonin norepinephrine reuptake inhibitor [SNRI]; and 15 healthy control subjects. The patients were separated into two equal groups in a double-blind, random manner, and 20 sessions of repeated TMS was applied to one group, and 20 sessions of sham TMS to the other. The Montgomery Asberg Depression Scale (MADRS), Hamilton Depression Rating Scale (HAM-D), Stroop test, Wisconsin Card Sorting Test (WCST), Digit Span Test (DST), Trail Making Test A-B, and Verbal Memory Processes Test (VMPT) were applied to the patients before and after the TMS procedure., Results: The decrease in the HAM-D score was greater in the active magnetic stimulation (25 trains, 10 Hz, 110% motor threshold intensity) group, and with the exception of verbal memory processes, better performance was obtained by the active magnetic stimulation group than the sham group in the cognitive function tests., Discussion: TMS was seen toimprove the cognitive defects present in the active phase of treatment-resistant depression, and therefore TMS could provide early improvement in cognitive functions in clinical use. Key words: Depression, transcranial magnetic stimulation, neurocognitive functi.
- Published
- 2023
- Full Text
- View/download PDF
19. Relationship of Apathy with Depressive Symptom Severity and Cognitive Functions in Geriatric Depression.
- Author
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Sözeri-Varma G, Bingöl C, Topak OZ, Enli Y, and Özdel O
- Abstract
Introduction: Apathy which is known as loss of primary motivation is observed more frequently in elderly depression in comparison with younger adults. It is put forth that apathy is related with depressive symptom severity and cognitive functions, that the existence of apathy may be a predictor of neurocognitive impairment. The objective of this study was to examine the apathy levels in elderly patients with major depression as well as the relationship between depressive symptom severity and cognitive functions., Methods: The study was carried out with 40 major depressive disorder patients (MDD) aged 60 and above, 40 healthy controls aged 60 and above. Sociodemographic data form, structured psychiatric interview (SCID-I), Hamilton Depression Rating Scale (HAM-D), Hamilton Anxiety Rating Scale (HAM-A), Montgomery-Asberg Depression Rating Scale (MADRS), Standardized Mini Mental State Examination (SMMSE), Montreal Cognitive Assessment Scale (MoCA), Apathy Evaluation Scale (AES) and Sheehan Disability Scale (SDS) were applied to the participants., Results: In our study, HAM-D, HAM-A and MADRS scale scores of MDD group was determined to be higher in comparison with those of the healthy control group. A positive correlation was determined in the MDD groups between the AES scores and depressive symptom severity, whereas a negative correlation was determined between the AES scores and cognitive functions. The SMMSE and MoCA scores of the geriatric MDD group were determined to be lower in comparison with healthy control group. Low performance was observed in the geriatric MDD group especially in the fields of orientation, visual/spatial functions, memory and language. Functionality was found to be lower in MDB group than in the control group, and functionality decreased as the level of apathy increased., Conclusion: Our results indicate that the apathy levels in geriatric depression are higher in comparison with the control group. Cognitive functions are affected adversely in geriatric patients in major depressive disorder, depressive symptom severity, impairment in cognitive functions and functionality are observed to be related with apathy level., Competing Interests: Conflict of Interest: The authors do not have any conflict of interest.
- Published
- 2019
- Full Text
- View/download PDF
20. [Adaptation and Reliability of the Structured Clinical Interview for DSM-5-Disorders - Clinician Version (SCID-5/CV) to the Turkish Language].
- Author
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Elbir M, Alp Topbaş Ö, Bayad S, Kocabaş T, Topak OZ, Çetin Ş, Özdel O, Ateşçi F, and Aydemir Ö
- Subjects
- Adolescent, Adult, Aged, Diagnostic and Statistical Manual of Mental Disorders, Female, Humans, Male, Middle Aged, Reproducibility of Results, Translations, Turkey, Young Adult, Interview, Psychological, Mental Disorders psychology, Psychiatric Status Rating Scales
- Abstract
Objective: In this study, we aimed to adapt the Structured Clinical Interview for DSM-5-ClinicianVersion into Turkish and to demonstrate its reliability. METHOD: A total of 185 patients, both inpatient and outpatient, from two different university hospitals were included. Training sessions on the features and use of SCID-5/CV were held before the data collection. During the study, in order to test the diagnostic agreement and accuracy, two psychiatrists remained present at the evaluation of each participant; alternatively being interviewer and the observer. Cohen's kappa coefficient for inter-rater reliability was calculated for every diagnostic category. RESULTS: The patient group had a mean age of 37.2 (±13.5) years and 55.7% were female. The education status was as follows: 2.7% were illiterate, 1.7% literate with no primary education, 33% had primary education, 23.8% had secondary education and 38.9% had higher education. The calculated kappa value showed excellent agreement for schizophrenia (κ=0.93), bipolar disorder (κ=0.96), major depressive disorder (κ=0.89), dysthymic disorder (κ=0.82), alcohol use disorder (κ=0.96), panic disorder (κ=0.84), agoraphobia (κ=0.85), social anxiety disorder (κ=0.95), generalized anxiety disorder (κ=0.89), obsessive compulsive disorder (κ=0.87), posttraumatic stress disorder (κ=0.89), adult attention deficit and hyperactivity disorder (κ=1.00), specific phobias (κ=0.82) and very good agreement with adjustment disorder (κ=0.78) and somatic symptom disorder (κ=0.65). CONCLUSION: Similar to the past SCID versions, kappa values were found to be quite high and all were statistically significant. The Turkish version of SCID-5/ CV can be reliably used in both clinical practice and clinical studies.
- Published
- 2019
21. [Is Clinical Insight Associated with Working Memory Components in Schizophrenia and Schizoaffective Disorder?]
- Author
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Tümkaya S, Hancı Yenigün E, Topak OZ, Şendur İ, Öztürk Atkaya N, and Özdel O
- Subjects
- Adult, Female, Humans, Male, Memory Disorders complications, Middle Aged, Neuropsychological Tests, Schizophrenic Psychology, Young Adult, Memory Disorders psychology, Schizophrenia complications
- Abstract
Objective: Previous studies suggest that the level of clinical insight in schizophrenia patients is related to working memory functions. However, these studies were not specifically concerned with the components of working memory and had not focused in detail on working memory functions. For this reason, the current study investigated the relationship between clinical insight and working memory components in patients with schizophrenia and schizoaffective disorder. METHOD: The patient group was evaluated by using the Scale for Assessment of Negative Symptoms, the Scale for Assessment of Positive Symptoms, and the Scale to Assess Unawareness of Mental Disorder to measure clinical insight. Moreover, all participants underwent a "Situation Awareness" test in order to measure working memory functions. Based on published data, the first stage of this test was accepted to measure the "visual spatial sketchpad" component of working memory, and the second stage was accepted to measure the "episodic buffer" (bound information storage) component. The functions of these components were measured separately as top-down and bottom-up cognitive processes. RESULTS: The episodic buffer function (managed by the bottom-up cognitive process) was related with clinical insight. This relationship also continued after correcting for the effect of positive symptoms on insight. The patients performed worse than the controls in terms of visual spatial sketchpad function, which was managed by both topdown and bottom-up cognitive processes. The patients performed worse than the controls in terms of both top-down and bottom-up cognitive processes and visual spatial sketchpad function. Furthermore, the patients were also worse than the controls in terms of episodic buffer function (managed by top-down cognitive processes). CONCLUSION: Clinical insight may be associated with binding function (associated with episodic buffer function) managed by bottom-up cognitive processes in patients with schizophrenia and schizoaffective disorder. Further studies are necessary to confirm this novel finding.
- Published
- 2019
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