1. A Case Report of Malignant Cerebellopontine Angle Lesion Highlighting the Interdisciplinary Diagnostic Challenge in the Case of Unilateral Progressive Hearing Loss.
- Author
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Marzolino, Riccardo, Castro, Veronica, Gambacorta, Valeria, Tonon, Eleonora, Cattaruzzi, Elisabetta, and Orzan, Eva
- Subjects
CEREBELLOPONTILE angle ,HEARING disorders ,SYMPTOMS ,ACOUSTIC neuroma ,LYMPHOBLASTIC leukemia ,SCHWANNOMAS ,VESTIBULAR apparatus diseases - Abstract
The authors present the case of a young boy who experienced progressive unilateral hearing loss initially believed to be unrelated to any other medical condition. Methods: The patient received a thorough evaluation, which included a comprehensive battery of audiological tests, a CT scan, and a gadolinium-enhanced MRI. Results: A repeated imaging investigation revealed the presence of a mass that mimicked a vestibular schwannoma (VS), but despite this, the boy was ultimately diagnosed with cerebral manifestations of B-cell acute lymphoblastic leukemia (B-ALL). Conclusions: Cerebral lesions originating from the internal auditory canal are rare in cases of B-ALL. In this case, the initial signs and symptoms of the disease were solely related to the audiovestibular system, making the diagnostic process particularly complicated. Unilateral hearing loss cases may indicate the presence of potentially life-threatening conditions, even if the hearing loss appears to be clinically non-syndromic. For these reasons, unilateral hearing losses necessitate a comprehensive interdisciplinary diagnostic approach from the very start of auditory manifestation and, in particular, if the hearing impairment demonstrates threshold progression. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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