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36 results on '"Tominaga, Kei"'

9. Self-study of the non-extension sign in an e-learning program improves diagnostic accuracy of invasion depth of early gastric cancer

Author

Kato, Minoru, additional, Uedo, Noriya, additional, Nagahama, Takashi, additional, Yao, Kenshi, additional, Doyama, Hisashi, additional, Tsuji, Shigetsugu, additional, Gotoda, Takuji, additional, Kawamura, Takuji, additional, Ebi, Masahide, additional, Yamamoto, Katsumi, additional, Akasaka, Tomofumi, additional, Takatori, Hajime, additional, Handa, Osamu, additional, Akamatsu, Takuji, additional, Nishikawa, Jun, additional, Hikichi, Takuto, additional, Yamashina, Takeshi, additional, Imoto, Akira, additional, Kitamura, Yoko, additional, Mikami, Tatsuya, additional, Koike, Tomoyuki, additional, Ohara, Shuichi, additional, Kitamura, Shinji, additional, Yamaguchi, Tatsuya, additional, Kinjo, Tetsu, additional, Inoue, Taro, additional, Suzuki, Sho, additional, Kaneko, Akihiro, additional, Hirasawa, Kingo, additional, Tanaka, Kyosuke, additional, Kotachi, Takahiro, additional, Miwa, Kazuhiro, additional, Toya, Yosuke, additional, Kayaba, Shoichi, additional, Ikehata, Atsushi, additional, Minami, Shinya, additional, Mizukami, Kazuhiro, additional, Oya, Hirohisa, additional, Ara, Nobuyuki, additional, Fukumoto, Yasushi, additional, Komura, Takuya, additional, Yoshio, Toshiyuki, additional, Morizono, Ryutaro, additional, Yamazaki, Kenji, additional, Shimodate, Yuichi, additional, Yamanouchi, Kohei, additional, Kawata, Noboru, additional, Kumagai, Masayuki, additional, Sato, Yoshinori, additional, Umeki, Kiyotaka, additional, Kawai, Daisuke, additional, Tanuma, Tokuma, additional, Kishino, Maiko, additional, Konishi, Jun, additional, Sumiyoshi, Tetsuya, additional, Oka, Shohei, additional, Kono, Mitsuhiro, additional, Sakamoto, Takeshi, additional, Horikawa, Yohei, additional, Ohyauchi, Motoki, additional, Hashiguchi, Keiichi, additional, Waseda, Yohei, additional, Kasai, Toyotaka, additional, Aoyagi, Hiroyuki, additional, Oyamada, Hirokazu, additional, Shoji, Masakuni, additional, Kiyotoki, Shu, additional, Asonuma, Sho, additional, Orikasa, Shunsuke, additional, Akaishi, Chika, additional, Nagami, Yasuaki, additional, Nakata, Satoshi, additional, Iida, Fumiyo, additional, Nomura, Tatsuma, additional, Tominaga, Kei, additional, Oka, Kohei, additional, Morita, Yoshinori, additional, Suzuki, Haruhisa, additional, Ozeki, Keiji, additional, Kuribayashi, Shiko, additional, Akazawa, Yoichi, additional, Sasaki, Sho, additional, Mikami, Tetsuhiko, additional, Miki, Goro, additional, Sano, Tatsushi, additional, Satoh, Hiro, additional, Nakamura, Munetaka, additional, Iwai, Wataru, additional, Tawa, Hideki, additional, Wada, Masafumi, additional, Yoshimura, Daisuke, additional, Hisanaga, Yasuhiro, additional, Shimokawa, Toshio, additional, and Ishikawa, Hideki, additional

Published
2019
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12. White globe appearance is a novel specific endoscopic marker for gastric cancer: A prospective study

Author

Yoshida, Naohiro, primary, Doyama, Hisashi, additional, Nakanishi, Hiroyoshi, additional, Tsuji, Kunihiro, additional, Tominaga, Kei, additional, Matsunaga, Kazuhiro, additional, Tsuji, Shigetsugu, additional, Takemura, Kenichi, additional, Yamada, Shinya, additional, Tsuyama, Sho, additional, Katayanagi, Kazuyoshi, additional, and Kurumaya, Hiroshi, additional

Published
2015
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13. The “white globe appearance” (WGA): a novel marker for a correct diagnosis of early gastric cancer by magnifying endoscopy with narrow-band imaging (M-NBI)

Author

Doyama, Hisashi, additional, Yoshida, Naohiro, additional, Tsuyama, Sho, additional, Ota, Ryosuke, additional, Takeda, Yasuhito, additional, Nakanishi, Hiroyoshi, additional, Tsuji, Kunihiro, additional, Tominaga, Kei, additional, Tsuji, Shigetsugu, additional, Takemura, Kenichi, additional, Yamada, Shinya, additional, Katayanagi, Kazuyoshi, additional, Kurumaya, Hiroshi, additional, Iwashita, Akinori, additional, and Yao, Kenshi, additional

Published
2015
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15. Detection of pharyngeal cancer in the overall population undergoing upper GI endoscopy by using narrow-band imaging: a single-center experience, 2009–2012

Author

Nakanishi, Hiroyoshi, primary, Doyama, Hisashi, additional, Takemura, Kenichi, additional, Yoshida, Naohiro, additional, Tsuji, Kunihiro, additional, Takeda, Yasuhito, additional, Asahina, Yoshiro, additional, Kito, Yosuke, additional, Ito, Renma, additional, Hayashi, Tomoyuki, additional, Hirano, Katsura, additional, Goto, Yoshinori, additional, Tominaga, Kei, additional, Inagaki, Satoko, additional, Waseda, Yohei, additional, Tsuji, Shigetsugu, additional, Miwa, Kazuhiro, additional, Kaneko, Yoshibumi, additional, Yamada, Shinya, additional, Kurumaya, Hiroshi, additional, Sakumoto, Makoto, additional, and Okada, Toshihide, additional

Published
2014
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16. Use of transoral endoscopy for pharyngeal examination: C ross‐sectional analysis

Author

Tsuji, Kunihiro, primary, Doyama, Hisashi, additional, Takeda, Yasuhito, additional, Takemura, Kenichi, additional, Yoshida, Naohiro, additional, Kito, Yosuke, additional, Asahina, Yoshiro, additional, Ito, Renma, additional, Nakanishi, Hiroyoshi, additional, Hayashi, Tomoyuki, additional, Inagaki, Satoko, additional, Tominaga, Kei, additional, Waseda, Yohei, additional, Tsuji, Shigetsugu, additional, Yamada, Shinya, additional, Hino, Shoryoku, additional, and Okada, Toshihide, additional

Published
2013
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17. Can flat-type brownish microlesions in the orohypopharynx be followed up without biopsy or endoscopic resection?

Author

Takemura, Kenichi, primary, Doyama, Hisashi, additional, Nakanishi, Hiroyoshi, additional, Takeda, Yasuhito, additional, Kito, Yosuke, additional, Ito, Renma, additional, Hayashi, Tomoyuki, additional, Tsuji, Kunihiro, additional, Tominaga, Kei, additional, Yoshida, Naohiro, additional, Waseda, Yohei, additional, Tsuji, Shigetsugu, additional, Yamada, Shinya, additional, Niwa, Hideki, additional, Katayanagi, Kazuyoshi, additional, Kurumaya, Hiroshi, additional, and Okada, Toshihide, additional

Published
2013
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30. The novel gene fad104, containing a fibronectin type III domain, has a significant role in adipogenesis

Author

Tominaga, Kei, Kondo, Chiharu, Johmura, Yoshikazu, Nishizuka, Makoto, and Imagawa, Masayoshi

Subjects
*FIBRONECTINS, *LECTINS, *PROTEIN analysis, *PEROXISOMES, *MICROBODIES
Abstract

A novel gene named fad104 (factor for adipocyte differentiation-104), whose expression level quickly increased in the early stage of adipogenesis, was isolated and characterized. The deduced amino acid sequence of fad104 revealed the possible presence of a fibronectin type III domain and transmembrane domain. The expression of fad104 was detected in adipocyte differentiable 3T3-L1 cells but not observed in the non-adipogenic cell line NIH-3T3. Moreover, the ability of 3T3-L1 cells to differentiate declined with the knockdown of fad104 by RNA interference, strongly indicating that fad104 functions as a positive regulator of adipogenesis. [Copyright &y& Elsevier]

Published
2004
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31. Usefulness of the clip-and-snare method using the pre-looping technique for endoscopic submucosal dissection of gastric neoplasia: a randomized controlled trial.

Author

Hasatani K, Yoshida N, Aoyagi H, Utsunomiya M, Naito Y, Matano Y, Tominaga K, Waseda Y, and Doyama H

Abstract

Background: The clip-and-snare method using the pre-looping technique (CSM-PLT) was developed as a traction method for endoscopic submucosal dissection (ESD) of gastric neoplasia. However, its usefulness has not been clearly established; thus, we aimed to assess the efficacy of CSM-PLT in gastric ESD., Methods: In this multicenter, randomized controlled trial, patients with gastric adenoma or carcinoma with absolute or expanded indications for ESD were randomized into conventional ESD and CSM-PLT groups, using the minimization method based on operator experience, tumor location, tumor size, and excision device. The primary endpoint was ESD procedure time. Secondary endpoints were en bloc and R0 resection rates, and complications ., Results: We enrolled 402 patients between July 2017 and February 2020. After excluding patients with deviations from the protocol, we finally analyzed the data of 192 and 186 patients in the conventional and CSM-PLT groups, respectively. The procedure time was significantly shorter in the CSM-PLT group than in the conventional group (58.0 vs. 69.7 min; P=0.009). All lesions were resected en bloc . The R0 resection rate tended to be higher in the CSM-PLT group (P=0.09). No significant differences in complications were observed between the 2 groups., Conclusions: CSM-PLT is beneficial for gastric ESD when compared with the conventional technique. CSM-PLT significantly reduced procedure times and improved R0 resection rates., Competing Interests: Conflict of Interest: None, (Copyright: © Hellenic Society of Gastroenterology.)

Published
2022
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32. Preoperative endoscopic diagnosis of superficial non-ampullary duodenal epithelial tumors, including magnifying endoscopy.

Author

Tsuji S, Doyama H, Tsuji K, Tsuyama S, Tominaga K, Yoshida N, Takemura K, Yamada S, Niwa H, Katayanagi K, Kurumaya H, and Okada T

Subjects
Adenocarcinoma surgery, Biopsy, Diagnosis, Differential, Duodenal Neoplasms surgery, Humans, Narrow Band Imaging, Neoplasm Staging, Predictive Value of Tests, Preoperative Care, Reproducibility of Results, Adenocarcinoma pathology, Duodenal Neoplasms pathology, Duodenoscopy methods, Image Enhancement methods
Abstract

Superficial non-ampullary duodenal epithelial tumor (SNADET) is defined as a sporadic tumor that is confined to the mucosa or submucosa that does not arise from Vater's papilla, and it includes adenoma and adenocarcinoma. Recent developments in endoscopic technology, such as high-resolution endoscopy and image-enhanced endoscopy, may increase the chances of detecting SNADET lesions. However, because SNADET is rare, little is known about its preoperative endoscopic diagnosis. The use of endoscopic resection for SNADET, which has no risk of metastasis, is increasing, but the incidence of complications, such as perforation, is significantly higher than in any other part of the digestive tract. A preoperative diagnosis is required to distinguish between lesions that should be followed up and those that require treatment. Retrospective studies have revealed certain endoscopic findings that suggest malignancy. In recent years, several new imaging modalities have been developed and explored for real-time diagnosis of these lesion types. Establishing an endoscopic diagnostic tool to differentiate between adenoma and adenocarcinoma in SNADET lesions is required to select the most appropriate treatment. This review describes the current state of knowledge about preoperative endoscopic diagnosis of SNADETs, such as duodenal adenoma and duodenal adenocarcinoma. Newer endoscopic techniques, including magnifying endoscopy, may help to guide these diagnostics, but their additional advantages remain unclear, and further studies are required to clarify these issues.

Published
2015
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33. [An autopsy case of pulmonary tumor thrombotic microangiopathy that occurred during chemotherapy for gastric cancer].

Author

Higashi K, Tsuji S, Tsuji K, Yoshida N, Tominaga K, Takemura K, Yamada S, Inaki N, Kurumaya H, and Doyama H

Subjects
Adenocarcinoma drug therapy, Humans, Male, Middle Aged, Stomach Neoplasms drug therapy, Adenocarcinoma pathology, Lung Neoplasms pathology, Neoplastic Cells, Circulating pathology, Pulmonary Embolism pathology, Stomach Neoplasms pathology, Thrombotic Microangiopathies pathology
Abstract

A man in 60s underwent total gastrectomy for advanced gastric cancer with para-aortic lymph node metastases. Although postoperative chemotherapy decreased the metastases, he was subsequently admitted with progressive respiratory distress. Pulmonary hypertension and right-sided heart failure developed, and he died of sudden cardiopulmonary arrest 30 hours after admission. Autopsy revealed widespread tumor embolism, fibrocellular intimal proliferation, and thrombus formation in the small arteries, consistent with a diagnosis of pulmonary tumor thrombotic microangiopathy (PTTM) associated with gastric cancer. Although PTTM a rare clinicopathological entity that causes severe pulmonary hypertension, it should be considered as a differential diagnosis for acute dyspnea or pulmonary hypertension in patients with carcinoma, regardless of clinical improvement.

Published
2014

34. [A case of disseminated carcinomatosis of bone marrow treated by S-1 and cisplatin after distal gastrectomy for early gastric cancer].

Author

Tsuji K, Doyama H, Yamada S, Kaneko Y, Takemura K, Tsuji S, Tominaga K, Inagaki S, Hayashi T, Ito R, Nakanishi H, Kitou Y, Takeda Y, Yamamoto M, Inaki N, Yamada T, Niwa H, Katayanagi K, and Kurumaya H

Subjects
Bone Marrow Neoplasms complications, Carcinoma pathology, Cisplatin administration & dosage, Disseminated Intravascular Coagulation etiology, Drug Combinations, Fatal Outcome, Gastrectomy, Humans, Male, Middle Aged, Neoplasm Staging, Oxonic Acid administration & dosage, Stomach Neoplasms pathology, Stomach Neoplasms surgery, Tegafur administration & dosage, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Bone Marrow Neoplasms drug therapy, Carcinoma drug therapy, Stomach Neoplasms drug therapy
Abstract

Patients with bone metastasis originating from gastric cancer experience complications from DIC. They are treated with anticoagulation therapy or platelet transfusion, but their prognosis is poor. Our case was a 50-year-old male who had undergone distal gastrectomy for early gastric cancer[pT1a(M)N0M0, pStage I a]ten years previously. He was admitted to our hospital complaining of backache. As a result of his examination, he was diagnosed with disseminated carcinosis of bone marrow with DIC as a postoperative recurrence of gastric cancer. The patient was treated with combination chemotherapy of S-1 and cisplatin(S-1 80 mg/body, po, day 1-21 and cisplatin 50mg/body, iv, day 8). After one course of treatment, DIC was resolved and his pain was relieved. He survived for about nine months. S-1 and cisplatin are considered to be effective for disseminated carcinosis of bone marrow.

Published
2012

35. [Significance of endoscopic transpapillary approach in diagnosis of intrabiliary growth type of hepatocellular carcinoma].

Author

Zenda T, Sawada T, Tominaga K, Taniguchi K, Takeshita Y, Okada T, Kaneko S, and Minato H

Subjects
Aged, Diagnostic Imaging, Humans, Male, Neoplasm Invasiveness, Bile Duct Neoplasms diagnosis, Bile Duct Neoplasms pathology, Bile Ducts pathology, Carcinoma, Hepatocellular diagnosis, Carcinoma, Hepatocellular pathology, Endoscopy, Digestive System methods, Liver Neoplasms diagnosis, Liver Neoplasms pathology
Published
2008

36. [Diffuse large B-cell lymphoma initially manifested by massive ascites and a small gastric lesion, clinically mimicking primary effusion lymphoma (PEL) in the abdominal cavity: a case report and review of the literature on Japanese PEL patients].

Author

Zenda T, Tominaga K, Choto S, Okada T, Kaneko S, and Minato H

Subjects
Ascites complications, Diagnosis, Differential, Humans, Lymphoma, Primary Effusion complications, Male, Middle Aged, Stomach Neoplasms pathology, Lymphoma, Large B-Cell, Diffuse diagnosis, Lymphoma, Primary Effusion diagnosis
Abstract

A 50-year-old man was admitted because of increasing massive ascites. While lymphoma cells (diffuse large B-cell lymphoma: DLBCL) were detected in the ascites, pleural effusion, cerebrospinal fluid and bone marrow, no tumor masses other than a submucosal lymphoma lesion in the stomach only 1 cm in diameter were identified. The patient was treated with chemotherapy including rituximab (R-CHOP-ESHAP) and injection of methotrexate and dexamethasone into the medullary cavity as well as radiation to the whole brain, and achieved complete remission 4 months later. The present case suggests that DLBCL can initially manifest as a form of effusion lymphoma with minimum solid tumor component. The distinctive clinical features of Japanese patients with primary effusion lymphoma are also reviewed.

Published
2007

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