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Your search keyword '"Tognellini, Rita"' showing total 11 results
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11 results on '"Tognellini, Rita"'

1. Haploidentical age-adapted myeloablative transplant and regulatory and effector T cells for acute myeloid leukemia

Author

Pierini, Antonio, Ruggeri, Loredana, Carotti, Alessandra, Falzetti, Franca, Saldi, Simonetta, Terenzi, Adelmo, Zucchetti, Claudio, Ingrosso, Gianluca, Zei, Tiziana, Iacucci Ostini, Roberta, Piccinelli, Sara, Bonato, Samanta, Tricarico, Sara, Mancusi, Antonella, Ciardelli, Sara, Limongello, Roberto, Merluzzi, Mara, Di Ianni, Mauro, Tognellini, Rita, Minelli, Olivia, Mecucci, Cristina, Martelli, Maria Paola, Falini, Brunangelo, Martelli, Massimo Fabrizio, Aristei, Cynthia, and Velardi, Andrea

Published
2021
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3. Use of DPB1 T‐cell epitope algorithm among italian transplant centers: A survey on behalf of Associazione Italiana di Immunogenetica e Biologia dei Trapianti

Author

Crocchiolo, Roberto, primary, Mele, Lia, additional, Testi, Manuela, additional, Scollo Chiara, Mariadele, additional, Murgia, Barbara, additional, Rossi, Angela, additional, Vecchiato, Cinzia, additional, Grammatico, Paola, additional, Mininni, Donata, additional, Longhi, Elena, additional, Manfroi, Silvia, additional, Giuliodori, Silvia, additional, Castellani, Laura, additional, Carella, Graziella, additional, Lai, Sara, additional, Azzaro Maria, Pia, additional, Mazzi, Benedetta, additional, Perotti, Laura, additional, Penta, Roberta, additional, Lombardo, Claudia, additional, Tognellini, Rita, additional, Andreani, Marco, additional, Albergoni Maria, Paola, additional, Nesci, Sonia, additional, Cappuzzo, Valentina, additional, Chiusolo, Patrizia, additional, Garino, Elena, additional, Cappucci, Giuseppe, additional, Ceschini, Nadia, additional, Bevilacqua, Elena, additional, Guizzardi, Elisabetta, additional, Tagliaferri Cinzia, Marina, additional, Piazza, Antonina, additional, Carcassi, Carlo, additional, and Miotti, Valeria, additional

Published
2021
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5. How Adoptive Immunotherapy with Conventional T and Regulatory T Cells Exerts a Gvl Effect without GvHD, after Haploidentical Hematopoietic Transplantation

Author

Ruggeri, Loredana, primary, Carotti, Alessandra, additional, Pierini, Antonio, additional, Falzetti, Franca, additional, Terenzi, Adelmo, additional, Urbani, Elena, additional, Lucia, Amico, additional, Tricarico, Sara, additional, Piccinelli, Sara, additional, Massei, Maria Speranza, additional, Ciardelli, Sara, additional, Di Ianni, Mauro, additional, Zei, Tiziana, additional, Iacucci Ostini, Roberta, additional, Lancellotta, Valentina, additional, Saldi, Simonetta, additional, Minelli, Olivia, additional, Tognellini, Rita, additional, Merluzzi, Mara, additional, Marchesi, Mauro, additional, Caniglia, Maurizio, additional, Aristei, Cynthia, additional, Falini, Brunangelo, additional, Martelli, Massimo Fabrizio, additional, and Velardi, Andrea, additional

Published
2018
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6. HLA-haploidentical transplantation with regulatory and conventional T-cell adoptive immunotherapy prevents acute leukemia relapse

Author

Martelli, Massimo F., primary, Di Ianni, Mauro, additional, Ruggeri, Loredana, additional, Falzetti, Franca, additional, Carotti, Alessandra, additional, Terenzi, Adelmo, additional, Pierini, Antonio, additional, Massei, Maria Speranza, additional, Amico, Lucia, additional, Urbani, Elena, additional, Del Papa, Beatrice, additional, Zei, Tiziana, additional, Iacucci Ostini, Roberta, additional, Cecchini, Debora, additional, Tognellini, Rita, additional, Reisner, Yair, additional, Aversa, Franco, additional, Falini, Brunangelo, additional, and Velardi, Andrea, additional

Published
2014
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7. Biological Markers and DNA Flow Cytometric Analysis in Radically Resected Patients with Non-Small Cell Lung Cancer. A Study of the Perugia Multidisciplinary Team for Thoracic Tumors

Author

Ludovini, Vienna, primary, Pistola, Lorenza, additional, Gregorc, Vanesa, additional, Floriani, Irene, additional, Rulli, Eliana, additional, Di Carlo, Luciana, additional, Semeraro, Antonia, additional, Daddi, Giuliano, additional, Darwish, Samir, additional, Stocchi, Lucia, additional, Tofanetti, Francesca Romana, additional, Bellezza, Guido, additional, Sidoni, Angelo, additional, Tognellini, Rita, additional, Crinò, Lucio, additional, and Tonato, Maurizio, additional

Published
2008
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8. Activation of Cord T Lymphocytes

Author

Gerli, Roberto, primary, Agea, Elisabetta, additional, Muscat, Christopher, additional, Ercolani, Raffaella, additional, Bistoni, Onelia, additional, Tognellini, Rita, additional, Mariggió, Maria A., additional, Spinozzi, Fabrizio, additional, and Bertotto, Alberto, additional

Published
1994
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9. Activation of Cord T Lymphocytes

Author

Gerli, Roberto, primary, Agea, Elisabetta, additional, Muscat, Chiristopher, additional, Tognellini, Rita, additional, Fiorucci, Giuliana, additional, Spinozzi, Fabrizio, additional, Cernetti, Cristina, additional, and Bertotto, Alberto, additional

Published
1993
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11. Natural Killer (NK)-Cell Function and Antileukemic Activity of a Large Population of CD3+/CD8+T Cells Expressing NK Receptors for Major Histocompatibility Complex Class I After “Three-Loci” HLA-Incompatible Bone Marrow Transplantation

Author

Albi, Nicola, Ruggeri, Loredana, Aversa, Franco, Merigiola, Carla, Tosti, Antonella, Tognellini, Rita, Grossi, Carlo E., Martelli, Massimo F., and Velardi, Andrea

Abstract

We have shown that addition of granulocyte colony-stimulating factor-mobilized peripheral blood progenitor cells to the marrow inoculum allows engraftment of T-cell depleted, “three loci” HLA-incompatible marrow transplants for acute leukemia. The event-free survival of patients at high risk for relapse prompted the present investigation of the antitumor potential of this transplant. Tumor-cell lysis by natural killer (NK) cells is regulated by inhibitory receptors for specific HLA class I alleles. Here, we report the postgrafting emergence of a large, donor-type CD3+/CD8+T-cell receptor (TcR)-αβ+cell population, barely detectable in normal subjects, that expresses 58 kD, “p58,” NK receptors for HLA-C locus alleles. Analysis of >900 clones revealed that 40% to 80% of these T cells exhibit NK-like function, ie, they lysed class I-targets and were functionally blocked by class I alleles on target cells. Monoclonal antibody-mediated blocking of class I recognition by these cells induced lysis of HLA-protected, autologous targets. The class l-mediated inhibitory signaling through the NK receptors also blocked TcR/CD3-triggered cytotoxicity of these cells, indicating that their antigen-specific responses may be impaired. However, the NK-like function of these cells allows them to discriminate normal cells, protected from lysis, from leukemic cells that were lysed and may be targets for a graft-versus-leukemia effect.

Published
1996
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