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33 results on '"Todorova, Boryana"'

1. The International Climate Psychology Collaboration: Climate change-related data collected from 63 countries

Author

Doell, Kimberly C., Todorova, Boryana, Vlasceanu, Madalina, Bak Coleman, Joseph B., Pronizius, Ekaterina, Schumann, Philipp, Azevedo, Flavio, Patel, Yash, Berkebile-Wineberg, Michael M., Brick, Cameron, Lange, Florian, Grayson, Samantha J., Pei, Yifei, Chakroff, Alek, van den Broek, Karlijn L., Lamm, Claus, Vlasceanu, Denisa, Constantino, Sara M., Rathje, Steve, Goldwert, Danielle, Fang, Ke, Aglioti, Salvatore Maria, Alfano, Mark, Alvarado-Yepez, Andy J., Andersen, Angélica, Anseel, Frederik, Apps, Matthew A. J., Asadli, Chillar, Awuor, Fonda Jane, Basaglia, Piero, Bélanger, Jocelyn J., Berger, Sebastian, Bertin, Paul, Białek, Michał, Bialobrzeska, Olga, Blaya-Burgo, Michelle, Bleize, Daniëlle N. M., Bø, Simen, Boecker, Lea, Boggio, Paulo S., Borau, Sylvie, Borau, Sylvie, Bos, Björn, Bouguettaya, Ayoub, Brauer, Markus, Brik, Tymofii, Briker, Roman, Brosch, Tobias, Buchel, Ondrej, Buonauro, Daniel, Butalia, Radhika, Carvacho, Héctor, Chamberlain, Sarah A. E., Chan, Hang-Yee, Chow, Dawn, Chung, Dongil, Cian, Luca, Cohen-Eick, Noa, Contreras-Huerta, Luis Sebastian, Contu, Davide, Cristea, Vladimir, Cutler, Jo, D’Ottone, Silvana, De keersmaecker, Jonas, Delcourt, Sarah, Delouvée, Sylvain, Diel, Kathi, Douglas, Benjamin D., Drupp, Moritz A., Dubey, Shreya, Ekmanis, Jānis, Elbaek, Christian T., Elsherif, Mahmoud, Engelhard, Iris M., Escher, Yannik A., Etienne, Tom W., Farage, Laura, Farias, Ana Rita, Feuerriegel, Stefan, Findor, Andrej, Freira, Lucia, Friese, Malte, Gains, Neil Philip, Gallyamova, Albina, Geiger, Sandra J., Genschow, Oliver, Gjoneska, Biljana, Gkinopoulos, Theofilos, Goldberg, Beth, Goldenberg, Amit, Gradidge, Sarah, Grassini, Simone, Gray, Kurt, Grelle, Sonja, Griffin, Siobhán M., Grigoryan, Lusine, Grigoryan, Ani, Grigoryev, Dmitry, Gruber, June, Guilaran, Johnrev, Hadar, Britt, Hahnel, Ulf J. J., Halperin, Eran, Harvey, Annelie J., Haugestad, Christian A. P., Herman, Aleksandra M., Hershfield, Hal E., Himichi, Toshiyuki, Hine, Donald W., Hofmann, Wilhelm, Howe, Lauren, Huaman-Chulluncuy, Enma T., Huang, Guanxiong, Ishii, Tatsunori, Ito, Ayahito, Jia, Fanli, Jost, John T., Jovanović, Veljko, Jurgiel, Dominika, Kácha, Ondřej, Kankaanpää, Reeta, Kantorowicz, Jaroslaw, Kantorowicz-Reznichenko, Elena, Mintz, Keren Kaplan, Kaya, Ilker, Kaya, Ozgur, Khachatryan, Narine, Klas, Anna, Klein, Colin, Klöckner, Christian A., Koppel, Lina, Kosachenko, Alexandra I., Kothe, Emily J., Krebs, Ruth, Krosch, Amy R., Krouwel, Andre P. M., Kyrychenko, Yara, Lagomarsino, Maria, Cunningham, Julia Lee, Lees, Jeffrey, Leung, Tak Yan, Levy, Neil, Lockwood, Patricia L., Longoni, Chiara, Ortega, Alberto López, Loschelder, David D., Lu, Jackson G., Luo, Yu, Luomba, Joseph, Lutz, Annika E., Majer, Johann M., Markowitz, Ezra, Marsh, Abigail A., Mascarenhas, Karen Louise, Mbilingi, Bwambale, Mbungu, Winfred, McHugh, Cillian, Meijers, Marijn H. C., Mercier, Hugo, Mhagama, Fenant Laurent, Michalaki, Katerina, Mikus, Nace, Milliron, Sarah G., Mitkidis, Panagiotis, Monge-Rodríguez, Fredy S., Mora, Youri L., Morais, Michael J., Moreau, David, Motoki, Kosuke, Moyano, Manuel, Mus, Mathilde, Navajas, Joaquin, Nguyen, Tam Luong, Nguyen, Dung Minh, Nguyen, Trieu, Niemi, Laura, Nijssen, Sari R. R., Nilsonne, Gustav, Nitschke, Jonas P., Nockur, Laila, Okura, Ritah, Öner, Sezin, Özdoğru, Asil Ali, Palumbo, Helena, Panagopoulos, Costas, Panasiti, Maria Serena, Pärnamets, Philip, Paruzel-Czachura, Mariola, Pavlov, Yuri G., Payán-Gómez, César, Pearson, Adam R., da Costa, Leonor Pereira, Petrowsky, Hannes M., Pfattheicher, Stefan, Pham, Nhat Tan, Ponizovskiy, Vladimir, Pretus, Clara, Rêgo, Gabriel G., Reimann, Ritsaart, Rhoads, Shawn A., Riano-Moreno, Julian, Richter, Isabell, Röer, Jan Philipp, Rosa-Sullivan, Jahred, Ross, Robert M., Sabherwal, Anandita, Saito, Toshiki, Sarrasin, Oriane, Say, Nicolas, Schmid, Katharina, Schmitt, Michael T., Schoenegger, Philipp, Scholz, Christin, Schug, Mariah G., Schulreich, Stefan, Shreedhar, Ganga, Shuman, Eric, Sivan, Smadar, Sjåstad, Hallgeir, Soliman, Meikel, Soud, Katia, Spampatti, Tobia, Sparkman, Gregg, Spasovski, Ognen, Stanley, Samantha K., Stern, Jessica A., Strahm, Noel, Suko, Yasushi, Sul, Sunhae, Syropoulos, Stylianos, Taylor, Neil C., Tedaldi, Elisa, Tinghög, Gustav, Huynh, Luu Duc Toan, Travaglino, Giovanni Antonio, Tsakiris, Manos, Tüter, İlayda, Tyrala, Michael, Uluğ, Özden Melis, Urbanek, Arkadiusz, Valko, Danila, van der Linden, Sander, van Schie, Kevin, van Stekelenburg, Aart, Vanags, Edmunds, Västfjäll, Daniel, Vesely, Stepan, Vintr, Jáchym, Vranka, Marek, Wanguche, Patrick Otuo, Willer, Robb, Wojcik, Adrian Dominik, Xu, Rachel, Yadav, Anjali, Zawisza, Magdalena, Zhao, Xian, Zhao, Jiaying, Żuk, Dawid, and Van Bavel, Jay J.

Published
2024
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3. Entorhinal grid-like codes and time-locked network dynamics track others navigating through space

Author

Wagner, Isabella C, Graichen, Luise P, Todorova, Boryana, Lüttig, Andre, Omer, David B, Stangl, Matthias, and Lamm, Claus

Subjects
Biological Psychology, Information and Computing Sciences, Psychology, Neurosciences, 1.1 Normal biological development and functioning, Underpinning research, Mental health, Humans, Brain, Computer Systems, Corpus Striatum, Entorhinal Cortex, Head
Abstract

Navigating through crowded, dynamically changing environments requires the ability to keep track of other individuals. Grid cells in the entorhinal cortex are a central component of self-related navigation but whether they also track others' movement is unclear. Here, we propose that entorhinal grid-like codes make an essential contribution to socio-spatial navigation. Sixty human participants underwent functional magnetic resonance imaging (fMRI) while observing and re-tracing different paths of a demonstrator that navigated a virtual reality environment. Results revealed that grid-like codes in the entorhinal cortex tracked the other individual navigating through space. The activity of grid-like codes was time-locked to increases in co-activation and entorhinal-cortical connectivity that included the striatum, the hippocampus, parahippocampal and right posterior parietal cortices. Surprisingly, the grid-related effects during observation were stronger the worse participants performed when subsequently re-tracing the demonstrator's paths. Our findings suggests that network dynamics time-locked to entorhinal grid-cell-related activity might serve to distribute information about the location of others throughout the brain.

Published
2023

5. Addressing climate change with behavioral science: A global intervention tournament in 63 countries

Author

Vlasceanu, Madalina, Doell, Kimberly C., Bak-Coleman, Joseph B., Todorova, Boryana, Berkebile-Weinberg, Michael M., Grayson, Samantha J., Patel, Yash, Goldwert, Danielle, Pei, Yifei, Chakroff, Alek, Pronizius, Ekaterina, van den Broek, Karlijn L., Vlasceanu, Denisa, Constantino, Sara, Morais, Michael J., Schumann, Philipp, Rathje, Steve, Fang, Ke, Aglioti, Salvatore Maria, Alfano, Mark, Alvarado-Yepez, Andy J., Andersen, Angélica, Anseel, Frederik, Apps, Matthew A. J., Asadli, Chillar, Awuor, Fonda Jane, Azevedo, Flavio, Basaglia, Piero, Bélanger, Jocelyn J., Berger, Sebastian, Bertin, Paul, Białek, Michał, Bialobrzeska, Olga, Blaya-Burgo, Michelle, Bleize, Daniëlle N. M., Bø, Simen, Boecker, Lea, Boggio, Paulo S., Borau, Sylvie, Bos, Björn, Bouguettaya, Ayoub, Brauer, Markus, Brick, Cameron, Brik, Tymofii, Briker, Roman, Brosch, Tobias, Engelhard, Iris M., Farias, Ana Rita, van Schie, Kevin, van Stekelenburg, Aart, Vlasceanu, Madalina, Doell, Kimberly C., Bak-Coleman, Joseph B., Todorova, Boryana, Berkebile-Weinberg, Michael M., Grayson, Samantha J., Patel, Yash, Goldwert, Danielle, Pei, Yifei, Chakroff, Alek, Pronizius, Ekaterina, van den Broek, Karlijn L., Vlasceanu, Denisa, Constantino, Sara, Morais, Michael J., Schumann, Philipp, Rathje, Steve, Fang, Ke, Aglioti, Salvatore Maria, Alfano, Mark, Alvarado-Yepez, Andy J., Andersen, Angélica, Anseel, Frederik, Apps, Matthew A. J., Asadli, Chillar, Awuor, Fonda Jane, Azevedo, Flavio, Basaglia, Piero, Bélanger, Jocelyn J., Berger, Sebastian, Bertin, Paul, Białek, Michał, Bialobrzeska, Olga, Blaya-Burgo, Michelle, Bleize, Daniëlle N. M., Bø, Simen, Boecker, Lea, Boggio, Paulo S., Borau, Sylvie, Bos, Björn, Bouguettaya, Ayoub, Brauer, Markus, Brick, Cameron, Brik, Tymofii, Briker, Roman, Brosch, Tobias, Engelhard, Iris M., Farias, Ana Rita, van Schie, Kevin, and van Stekelenburg, Aart

Abstract

Effectively reducing climate change requires marked, global behavior change. However, it is unclear which strategies are most likely to motivate people to change their climate beliefs and behaviors. Here, we tested 11 expert-crowdsourced interventions on four climate mitigation outcomes: beliefs, policy support, information sharing intention, and an effortful tree-planting behavioral task. Across 59,440 participants from 63 countries, the interventions' effectiveness was small, largely limited to nonclimate skeptics, and differed across outcomes: Beliefs were strengthened mostly by decreasing psychological distance (by 2.3%), policy support by writing a letter to a future-generation member (2.6%), information sharing by negative emotion induction (12.1%), and no intervention increased the more effortful behavior-several interventions even reduced tree planting. Last, the effects of each intervention differed depending on people's initial climate beliefs. These findings suggest that the impact of behavioral climate interventions varies across audiences and target behaviors.

Published
2024

6. Addressing climate change with behavioral science: A global intervention tournament in 63 countries

Author

Organisations and Sustainability, Leerstoel Engelhard, Experimental psychopathology, Innovation Studies, Clinical Psychology (overkoepelend voor heel KP), Vlasceanu, Madalina, Doell, Kimberly C., Bak-Coleman, Joseph B., Todorova, Boryana, Berkebile-Weinberg, Michael M., Grayson, Samantha J., Patel, Yash, Goldwert, Danielle, Pei, Yifei, Chakroff, Alek, Pronizius, Ekaterina, van den Broek, Karlijn L., Vlasceanu, Denisa, Constantino, Sara, Morais, Michael J., Schumann, Philipp, Rathje, Steve, Fang, Ke, Aglioti, Salvatore Maria, Alfano, Mark, Alvarado-Yepez, Andy J., Andersen, Angélica, Anseel, Frederik, Apps, Matthew A. J., Asadli, Chillar, Awuor, Fonda Jane, Azevedo, Flavio, Basaglia, Piero, Bélanger, Jocelyn J., Berger, Sebastian, Bertin, Paul, Białek, Michał, Bialobrzeska, Olga, Blaya-Burgo, Michelle, Bleize, Daniëlle N. M., Bø, Simen, Boecker, Lea, Boggio, Paulo S., Borau, Sylvie, Bos, Björn, Bouguettaya, Ayoub, Brauer, Markus, Brick, Cameron, Brik, Tymofii, Briker, Roman, Brosch, Tobias, Engelhard, Iris M., Farias, Ana Rita, van Schie, Kevin, van Stekelenburg, Aart, Organisations and Sustainability, Leerstoel Engelhard, Experimental psychopathology, Innovation Studies, Clinical Psychology (overkoepelend voor heel KP), Vlasceanu, Madalina, Doell, Kimberly C., Bak-Coleman, Joseph B., Todorova, Boryana, Berkebile-Weinberg, Michael M., Grayson, Samantha J., Patel, Yash, Goldwert, Danielle, Pei, Yifei, Chakroff, Alek, Pronizius, Ekaterina, van den Broek, Karlijn L., Vlasceanu, Denisa, Constantino, Sara, Morais, Michael J., Schumann, Philipp, Rathje, Steve, Fang, Ke, Aglioti, Salvatore Maria, Alfano, Mark, Alvarado-Yepez, Andy J., Andersen, Angélica, Anseel, Frederik, Apps, Matthew A. J., Asadli, Chillar, Awuor, Fonda Jane, Azevedo, Flavio, Basaglia, Piero, Bélanger, Jocelyn J., Berger, Sebastian, Bertin, Paul, Białek, Michał, Bialobrzeska, Olga, Blaya-Burgo, Michelle, Bleize, Daniëlle N. M., Bø, Simen, Boecker, Lea, Boggio, Paulo S., Borau, Sylvie, Bos, Björn, Bouguettaya, Ayoub, Brauer, Markus, Brick, Cameron, Brik, Tymofii, Briker, Roman, Brosch, Tobias, Engelhard, Iris M., Farias, Ana Rita, van Schie, Kevin, and van Stekelenburg, Aart

Published
2024

7. Addressing climate change with behavioral science:A global intervention tournament in 63 countries

Author

Vlasceanu, Madalina, Doell, Kimberly C., Bak-Coleman, Joseph B., Todorova, Boryana, Berkebile-Weinberg, Michael M., Grayson, Samantha J., Patel, Yash, Goldwert, Danielle, Pei, Yifei, Chakroff, Alek, Pronizius, Ekaterina, van den Broek, Karlijn L., Vlasceanu, Denisa, Constantino, Sara, Morais, Michael J., Schumann, Philipp, Rathje, Steve, Fang, Ke, Aglioti, Salvatore Maria, Alfano, Mark, Alvarado-Yepez, Andy J., Andersen, Angélica, Anseel, Frederik, Apps, Matthew A.J., Asadli, Chillar, Awuor, Fonda Jane, Azevedo, Flavio, Basaglia, Piero, Bélanger, Jocelyn J., Berger, Sebastian, Bertin, Paul, Białek, Michał, Bialobrzeska, Olga, Blaya-Burgo, Michelle, Bleize, Daniëlle N.M., Bø, Simen, Boecker, Lea, Boggio, Paulo S., Borau, Sylvie, Bos, Björn, Bouguettaya, Ayoub, Brauer, Markus, Brick, Cameron, Brik, Tymofii, Briker, Roman, Brosch, Tobias, Buchel, Ondrej, Buonauro, Daniel, Butalia, Radhika, Carvacho, Héctor, Chamberlain, Sarah A.E., Chan, Hang Yee, Chow, Dawn, Chung, Dongil, Cian, Luca, Cohen-Eick, Noa, Contreras-Huerta, Luis Sebastian, Contu, Davide, Cristea, Vladimir, Cutler, Jo, D'Ottone, Silvana, De Keersmaecker, Jonas, Delcourt, Sarah, Delouvée, Sylvain, Diel, Kathi, Douglas, Benjamin D., Drupp, Moritz A., Dubey, Shreya, Ekmanis, Jānis, Elbaek, Christian T., Elsherif, Mahmoud, Engelhard, Iris M., Escher, Yannik A., Etienne, Tom W., Farage, Laura, Farias, Ana Rita, Feuerriegel, Stefan, Findor, Andrej, Freira, Lucia, Friese, Malte, Gains, Neil Philip, Gallyamova, Albina, Geiger, Sandra J., Genschow, Oliver, Gjoneska, Biljana, Gkinopoulos, Theofilos, Goldberg, Beth, Goldenberg, Amit, Gradidge, Sarah, Grassini, Simone, Gray, Kurt, Grelle, Sonja, Griffin, Siobhán M., Grigoryan, Lusine, Grigoryan, Ani, Grigoryev, Dmitry, Gruber, June, Guilaran, Johnrev, Hadar, Britt, Hahnel, Ulf J.J., Halperin, Eran, Harvey, Annelie J., Haugestad, Christian A.P., Herman, Aleksandra M., Hershfield, Hal E., Himichi, Toshiyuki, Hine, Donald W., Hofmann, Wilhelm, Howe, Lauren, Huaman-Chulluncuy, Enma T., Huang, Guanxiong, Ishii, Tatsunori, Ito, Ayahito, Jia, Fanli, Jost, John T., Jovanović, Veljko, Jurgiel, Dominika, Kácha, Ondřej, Kankaanpää, Reeta, Kantorowicz, Jaroslaw, Kantorowicz-Reznichenko, Elena, Kaplan Mintz, Keren, Kaya, Ilker, Kaya, Ozgur, Khachatryan, Narine, Klas, Anna, Klein, Colin, Klöckner, Christian A., Koppel, Lina, Kosachenko, Alexandra I., Kothe, Emily J., Krebs, Ruth, Krosch, Amy R., Krouwel, Andre P.M., Kyrychenko, Yara, Lagomarsino, Maria, Lamm, Claus, Lange, Florian, Lee Cunningham, Julia, Lees, Jeffrey, Leung, Tak Yan, Levy, Neil, Lockwood, Patricia L., Longoni, Chiara, López Ortega, Alberto, Loschelder, David D., Lu, Jackson G., Luo, Yu, Luomba, Joseph, Lutz, Annika E., Majer, Johann M., Markowitz, Ezra, Marsh, Abigail A., Mascarenhas, Karen Louise, Mbilingi, Bwambale, Mbungu, Winfred, McHugh, Cillian, Meijers, Marijn H.C., Mercier, Hugo, Mhagama, Fenant Laurent, Michalakis, Katerina, Mikus, Nace, Milliron, Sarah, Mitkidis, Panagiotis, Monge-Rodríguez, Fredy S., Mora, Youri L., Moreau, David, Motoki, Kosuke, Moyano, Manuel, Mus, Mathilde, Navajas, Joaquin, Nguyen, Tam Luong, Nguyen, Dung Minh, Nguyen, Trieu, Niemi, Laura, Nijssen, Sari R.R., Nilsonne, Gustav, Nitschke, Jonas P., Nockur, Laila, Okura, Ritah, Öner, Sezin, Özdoğru, Asil Ali, Palumbo, Helena, Panagopoulos, Costas, Panasiti, Maria Serena, Pärnamets, Philip, Paruzel-Czachura, Mariola, Pavlov, Yuri G., Payán-Gómez, César, Pearson, Adam R., Pereira da Costa, Leonor, Petrowsky, Hannes M., Pfattheicher, Stefan, Pham, Nhat Tan, Ponizovskiy, Vladimir, Pretus, Clara, Rêgo, Gabriel G., Reimann, Ritsaart, Rhoads, Shawn A., Riano-Moreno, Julian, Richter, Isabell, Röer, Jan Philipp, Rosa-Sullivan, Jahred, Ross, Robert M., Sabherwal, Anandita, Saito, Toshiki, Sarrasin, Oriane, Say, Nicolas, Schmid, Katharina, Schmitt, Michael T., Schoenegger, Philipp, Scholz, Christin, Schug, Mariah G., Schulreich, Stefan, Shreedhar, Ganga, Shuman, Eric, Sivan, Smadar, Sjåstad, Hallgeir, Soliman, Meikel, Soud, Katia, Spampatti, Tobia, Sparkman, Gregg, Spasovski, Ognen, Stanley, Samantha K., Stern, Jessica A., Strahm, Noel, Suko, Yasushi, Sul, Sunhae, Syropoulos, Stylianos, Taylor, Neil C., Tedaldi, Elisa, Tinghög, Gustav, Huynh, Luu Duc Toan, Travaglino, Giovanni Antonio, Tsakiris, Manos, Tüter, İlayda, Tyrala, Michael, Uluğ, Özden Melis, Urbanek, Arkadiusz, Valko, Danila, van der Linden, Sander, van Schie, Kevin, van Stekelenburg, Aart, Vanags, Edmunds, Västfjäll, Daniel, Vesely, Stepan, Vintr, Jáchym, Vranka, Marek, Wanguche, Patrick Otuo, Willer, Robb, Wojcik, Adrian Dominik, Xu, Rachel, Yadav, Anjali, Zawisza, Magdalena, Zhao, Xian, Zhao, Jiaying, Żuk, Dawid, Van Bavel, Jay J., Vlasceanu, Madalina, Doell, Kimberly C., Bak-Coleman, Joseph B., Todorova, Boryana, Berkebile-Weinberg, Michael M., Grayson, Samantha J., Patel, Yash, Goldwert, Danielle, Pei, Yifei, Chakroff, Alek, Pronizius, Ekaterina, van den Broek, Karlijn L., Vlasceanu, Denisa, Constantino, Sara, Morais, Michael J., Schumann, Philipp, Rathje, Steve, Fang, Ke, Aglioti, Salvatore Maria, Alfano, Mark, Alvarado-Yepez, Andy J., Andersen, Angélica, Anseel, Frederik, Apps, Matthew A.J., Asadli, Chillar, Awuor, Fonda Jane, Azevedo, Flavio, Basaglia, Piero, Bélanger, Jocelyn J., Berger, Sebastian, Bertin, Paul, Białek, Michał, Bialobrzeska, Olga, Blaya-Burgo, Michelle, Bleize, Daniëlle N.M., Bø, Simen, Boecker, Lea, Boggio, Paulo S., Borau, Sylvie, Bos, Björn, Bouguettaya, Ayoub, Brauer, Markus, Brick, Cameron, Brik, Tymofii, Briker, Roman, Brosch, Tobias, Buchel, Ondrej, Buonauro, Daniel, Butalia, Radhika, Carvacho, Héctor, Chamberlain, Sarah A.E., Chan, Hang Yee, Chow, Dawn, Chung, Dongil, Cian, Luca, Cohen-Eick, Noa, Contreras-Huerta, Luis Sebastian, Contu, Davide, Cristea, Vladimir, Cutler, Jo, D'Ottone, Silvana, De Keersmaecker, Jonas, Delcourt, Sarah, Delouvée, Sylvain, Diel, Kathi, Douglas, Benjamin D., Drupp, Moritz A., Dubey, Shreya, Ekmanis, Jānis, Elbaek, Christian T., Elsherif, Mahmoud, Engelhard, Iris M., Escher, Yannik A., Etienne, Tom W., Farage, Laura, Farias, Ana Rita, Feuerriegel, Stefan, Findor, Andrej, Freira, Lucia, Friese, Malte, Gains, Neil Philip, Gallyamova, Albina, Geiger, Sandra J., Genschow, Oliver, Gjoneska, Biljana, Gkinopoulos, Theofilos, Goldberg, Beth, Goldenberg, Amit, Gradidge, Sarah, Grassini, Simone, Gray, Kurt, Grelle, Sonja, Griffin, Siobhán M., Grigoryan, Lusine, Grigoryan, Ani, Grigoryev, Dmitry, Gruber, June, Guilaran, Johnrev, Hadar, Britt, Hahnel, Ulf J.J., Halperin, Eran, Harvey, Annelie J., Haugestad, Christian A.P., Herman, Aleksandra M., Hershfield, Hal E., Himichi, Toshiyuki, Hine, Donald W., Hofmann, Wilhelm, Howe, Lauren, Huaman-Chulluncuy, Enma T., Huang, Guanxiong, Ishii, Tatsunori, Ito, Ayahito, Jia, Fanli, Jost, John T., Jovanović, Veljko, Jurgiel, Dominika, Kácha, Ondřej, Kankaanpää, Reeta, Kantorowicz, Jaroslaw, Kantorowicz-Reznichenko, Elena, Kaplan Mintz, Keren, Kaya, Ilker, Kaya, Ozgur, Khachatryan, Narine, Klas, Anna, Klein, Colin, Klöckner, Christian A., Koppel, Lina, Kosachenko, Alexandra I., Kothe, Emily J., Krebs, Ruth, Krosch, Amy R., Krouwel, Andre P.M., Kyrychenko, Yara, Lagomarsino, Maria, Lamm, Claus, Lange, Florian, Lee Cunningham, Julia, Lees, Jeffrey, Leung, Tak Yan, Levy, Neil, Lockwood, Patricia L., Longoni, Chiara, López Ortega, Alberto, Loschelder, David D., Lu, Jackson G., Luo, Yu, Luomba, Joseph, Lutz, Annika E., Majer, Johann M., Markowitz, Ezra, Marsh, Abigail A., Mascarenhas, Karen Louise, Mbilingi, Bwambale, Mbungu, Winfred, McHugh, Cillian, Meijers, Marijn H.C., Mercier, Hugo, Mhagama, Fenant Laurent, Michalakis, Katerina, Mikus, Nace, Milliron, Sarah, Mitkidis, Panagiotis, Monge-Rodríguez, Fredy S., Mora, Youri L., Moreau, David, Motoki, Kosuke, Moyano, Manuel, Mus, Mathilde, Navajas, Joaquin, Nguyen, Tam Luong, Nguyen, Dung Minh, Nguyen, Trieu, Niemi, Laura, Nijssen, Sari R.R., Nilsonne, Gustav, Nitschke, Jonas P., Nockur, Laila, Okura, Ritah, Öner, Sezin, Özdoğru, Asil Ali, Palumbo, Helena, Panagopoulos, Costas, Panasiti, Maria Serena, Pärnamets, Philip, Paruzel-Czachura, Mariola, Pavlov, Yuri G., Payán-Gómez, César, Pearson, Adam R., Pereira da Costa, Leonor, Petrowsky, Hannes M., Pfattheicher, Stefan, Pham, Nhat Tan, Ponizovskiy, Vladimir, Pretus, Clara, Rêgo, Gabriel G., Reimann, Ritsaart, Rhoads, Shawn A., Riano-Moreno, Julian, Richter, Isabell, Röer, Jan Philipp, Rosa-Sullivan, Jahred, Ross, Robert M., Sabherwal, Anandita, Saito, Toshiki, Sarrasin, Oriane, Say, Nicolas, Schmid, Katharina, Schmitt, Michael T., Schoenegger, Philipp, Scholz, Christin, Schug, Mariah G., Schulreich, Stefan, Shreedhar, Ganga, Shuman, Eric, Sivan, Smadar, Sjåstad, Hallgeir, Soliman, Meikel, Soud, Katia, Spampatti, Tobia, Sparkman, Gregg, Spasovski, Ognen, Stanley, Samantha K., Stern, Jessica A., Strahm, Noel, Suko, Yasushi, Sul, Sunhae, Syropoulos, Stylianos, Taylor, Neil C., Tedaldi, Elisa, Tinghög, Gustav, Huynh, Luu Duc Toan, Travaglino, Giovanni Antonio, Tsakiris, Manos, Tüter, İlayda, Tyrala, Michael, Uluğ, Özden Melis, Urbanek, Arkadiusz, Valko, Danila, van der Linden, Sander, van Schie, Kevin, van Stekelenburg, Aart, Vanags, Edmunds, Västfjäll, Daniel, Vesely, Stepan, Vintr, Jáchym, Vranka, Marek, Wanguche, Patrick Otuo, Willer, Robb, Wojcik, Adrian Dominik, Xu, Rachel, Yadav, Anjali, Zawisza, Magdalena, Zhao, Xian, Zhao, Jiaying, Żuk, Dawid, and Van Bavel, Jay J.

Abstract

Effectively reducing climate change requires marked, global behavior change. However, it is unclear which strategies are most likely to motivate people to change their climate beliefs and behaviors. Here, we tested 11 expert-crowdsourced interventions on four climate mitigation outcomes: beliefs, policy support, information sharing intention, and an effortful tree-planting behavioral task. Across 59,440 participants from 63 countries, the interventions' effectiveness was small, largely limited to nonclimate skeptics, and differed across outcomes: Beliefs were strengthened mostly by decreasing psychological distance (by 2.3%), policy support by writing a letter to a future-generation member (2.6%), information sharing by negative emotion induction (12.1%), and no intervention increased the more effortful behavior-several interventions even reduced tree planting. Last, the effects of each intervention differed depending on people's initial climate beliefs. These findings suggest that the impact of behavioral climate interventions varies across audiences and target behaviors.

Published
2024

8. Acute stress reduces effortful prosocial behaviour

Author

Forbes, Paul AG; https://orcid.org/0000-0002-0138-8508, Aydogan, Gökhan; https://orcid.org/0000-0003-2187-7912, Braunstein, Julia; https://orcid.org/0000-0002-0006-6590, Todorova, Boryana; https://orcid.org/0000-0003-4840-498X, Wagner, Isabella C; https://orcid.org/0000-0002-4383-8204, Lockwood, Patricia L, Apps, Matthew AJ, Ruff, Christian C; https://orcid.org/0000-0002-3964-2364, Lamm, Claus; https://orcid.org/0000-0002-5422-0653, Forbes, Paul AG; https://orcid.org/0000-0002-0138-8508, Aydogan, Gökhan; https://orcid.org/0000-0003-2187-7912, Braunstein, Julia; https://orcid.org/0000-0002-0006-6590, Todorova, Boryana; https://orcid.org/0000-0003-4840-498X, Wagner, Isabella C; https://orcid.org/0000-0002-4383-8204, Lockwood, Patricia L, Apps, Matthew AJ, Ruff, Christian C; https://orcid.org/0000-0002-3964-2364, and Lamm, Claus; https://orcid.org/0000-0002-5422-0653

Abstract

Acute stress can change our cognition and emotions, but what specific consequences this has for human prosocial behaviour is unclear. Previous studies have mainly investigated prosociality with financial transfers in economic games and produced conflicting results. Yet a core feature of many types of prosocial behaviour is that they are effortful. We therefore examined how acute stress changes our willingness to exert effort that benefits others. Healthy male participants – half of whom were put under acute stress – made decisions whether to exert physical effort to gain money for themselves or another person. With this design, we could independently assess the effects of acute stress on prosocial, compared to self-benefitting, effortful behaviour. Compared to controls (n = 45), participants in the stress group (n = 46) chose to exert effort more often for self- than for other-benefitting rewards at a low level of effort. Additionally, the adverse effects of stress on prosocial effort were particularly pronounced in more selfish participants. Neuroimaging combined with computational modelling revealed a putative neural mechanism underlying these effects: more stressed participants showed increased activation to subjective value in the dorsal anterior cingulate cortex and anterior insula when they themselves could benefit from their exerted effort relative to when someone else could. By using an effort-based task that better approximates real-life prosocial behaviour and incorporating trait differences in prosocial tendencies, our study provides important insights into how acute stress affects prosociality and its associated neural mechanisms.

Published
2024

9. Addressing climate change with behavioral science: A global intervention tournament in 63 countries

Author

Vlasceanu, Madalina, primary, Doell, Kimberly C., additional, Bak-Coleman, Joseph B., additional, Todorova, Boryana, additional, Berkebile-Weinberg, Michael M., additional, Grayson, Samantha J., additional, Patel, Yash, additional, Goldwert, Danielle, additional, Pei, Yifei, additional, Chakroff, Alek, additional, Pronizius, Ekaterina, additional, van den Broek, Karlijn L., additional, Vlasceanu, Denisa, additional, Constantino, Sara, additional, Morais, Michael J., additional, Schumann, Philipp, additional, Rathje, Steve, additional, Fang, Ke, additional, Aglioti, Salvatore Maria, additional, Alfano, Mark, additional, Alvarado-Yepez, Andy J., additional, Andersen, Angélica, additional, Anseel, Frederik, additional, Apps, Matthew A. J., additional, Asadli, Chillar, additional, Awuor, Fonda Jane, additional, Azevedo, Flavio, additional, Basaglia, Piero, additional, Bélanger, Jocelyn J., additional, Berger, Sebastian, additional, Bertin, Paul, additional, Białek, Michał, additional, Bialobrzeska, Olga, additional, Blaya-Burgo, Michelle, additional, Bleize, Daniëlle N. M., additional, Bø, Simen, additional, Boecker, Lea, additional, Boggio, Paulo S., additional, Borau, Sylvie, additional, Bos, Björn, additional, Bouguettaya, Ayoub, additional, Brauer, Markus, additional, Brick, Cameron, additional, Brik, Tymofii, additional, Briker, Roman, additional, Brosch, Tobias, additional, Buchel, Ondrej, additional, Buonauro, Daniel, additional, Butalia, Radhika, additional, Carvacho, Héctor, additional, Chamberlain, Sarah A. E., additional, Chan, Hang-Yee, additional, Chow, Dawn, additional, Chung, Dongil, additional, Cian, Luca, additional, Cohen-Eick, Noa, additional, Contreras-Huerta, Luis Sebastian, additional, Contu, Davide, additional, Cristea, Vladimir, additional, Cutler, Jo, additional, D'Ottone, Silvana, additional, De Keersmaecker, Jonas, additional, Delcourt, Sarah, additional, Delouvée, Sylvain, additional, Diel, Kathi, additional, Douglas, Benjamin D., additional, Drupp, Moritz A., additional, Dubey, Shreya, additional, Ekmanis, Jānis, additional, Elbaek, Christian T., additional, Elsherif, Mahmoud, additional, Engelhard, Iris M., additional, Escher, Yannik A., additional, Etienne, Tom W., additional, Farage, Laura, additional, Farias, Ana Rita, additional, Feuerriegel, Stefan, additional, Findor, Andrej, additional, Freira, Lucia, additional, Friese, Malte, additional, Gains, Neil Philip, additional, Gallyamova, Albina, additional, Geiger, Sandra J., additional, Genschow, Oliver, additional, Gjoneska, Biljana, additional, Gkinopoulos, Theofilos, additional, Goldberg, Beth, additional, Goldenberg, Amit, additional, Gradidge, Sarah, additional, Grassini, Simone, additional, Gray, Kurt, additional, Grelle, Sonja, additional, Griffin, Siobhán M., additional, Grigoryan, Lusine, additional, Grigoryan, Ani, additional, Grigoryev, Dmitry, additional, Gruber, June, additional, Guilaran, Johnrev, additional, Hadar, Britt, additional, Hahnel, Ulf J.J., additional, Halperin, Eran, additional, Harvey, Annelie J., additional, Haugestad, Christian A. P., additional, Herman, Aleksandra M., additional, Hershfield, Hal E., additional, Himichi, Toshiyuki, additional, Hine, Donald W., additional, Hofmann, Wilhelm, additional, Howe, Lauren, additional, Huaman-Chulluncuy, Enma T., additional, Huang, Guanxiong, additional, Ishii, Tatsunori, additional, Ito, Ayahito, additional, Jia, Fanli, additional, Jost, John T., additional, Jovanović, Veljko, additional, Jurgiel, Dominika, additional, Kácha, Ondřej, additional, Kankaanpää, Reeta, additional, Kantorowicz, Jaroslaw, additional, Kantorowicz-Reznichenko, Elena, additional, Kaplan Mintz, Keren, additional, Kaya, Ilker, additional, Kaya, Ozgur, additional, Khachatryan, Narine, additional, Klas, Anna, additional, Klein, Colin, additional, Klöckner, Christian A., additional, Koppel, Lina, additional, Kosachenko, Alexandra I., additional, Kothe, Emily J., additional, Krebs, Ruth, additional, Krosch, Amy R., additional, Krouwel, Andre P.M., additional, Kyrychenko, Yara, additional, Lagomarsino, Maria, additional, Lamm, Claus, additional, Lange, Florian, additional, Lee Cunningham, Julia, additional, Lees, Jeffrey, additional, Leung, Tak Yan, additional, Levy, Neil, additional, Lockwood, Patricia L., additional, Longoni, Chiara, additional, López Ortega, Alberto, additional, Loschelder, David D., additional, Lu, Jackson G., additional, Luo, Yu, additional, Luomba, Joseph, additional, Lutz, Annika E., additional, Majer, Johann M., additional, Markowitz, Ezra, additional, Marsh, Abigail A., additional, Mascarenhas, Karen Louise, additional, Mbilingi, Bwambale, additional, Mbungu, Winfred, additional, McHugh, Cillian, additional, Meijers, Marijn H.C., additional, Mercier, Hugo, additional, Mhagama, Fenant Laurent, additional, Michalakis, Katerina, additional, Mikus, Nace, additional, Milliron, Sarah, additional, Mitkidis, Panagiotis, additional, Monge-Rodríguez, Fredy S., additional, Mora, Youri L., additional, Moreau, David, additional, Motoki, Kosuke, additional, Moyano, Manuel, additional, Mus, Mathilde, additional, Navajas, Joaquin, additional, Nguyen, Tam Luong, additional, Nguyen, Dung Minh, additional, Nguyen, Trieu, additional, Niemi, Laura, additional, Nijssen, Sari R. R., additional, Nilsonne, Gustav, additional, Nitschke, Jonas P., additional, Nockur, Laila, additional, Okura, Ritah, additional, Öner, Sezin, additional, Özdoğru, Asil Ali, additional, Palumbo, Helena, additional, Panagopoulos, Costas, additional, Panasiti, Maria Serena, additional, Pärnamets, Philip, additional, Paruzel-Czachura, Mariola, additional, Pavlov, Yuri G., additional, Payán-Gómez, César, additional, Pearson, Adam R., additional, Pereira da Costa, Leonor, additional, Petrowsky, Hannes M., additional, Pfattheicher, Stefan, additional, Pham, Nhat Tan, additional, Ponizovskiy, Vladimir, additional, Pretus, Clara, additional, Rêgo, Gabriel G., additional, Reimann, Ritsaart, additional, Rhoads, Shawn A., additional, Riano-Moreno, Julian, additional, Richter, Isabell, additional, Röer, Jan Philipp, additional, Rosa-Sullivan, Jahred, additional, Ross, Robert M., additional, Sabherwal, Anandita, additional, Saito, Toshiki, additional, Sarrasin, Oriane, additional, Say, Nicolas, additional, Schmid, Katharina, additional, Schmitt, Michael T., additional, Schoenegger, Philipp, additional, Scholz, Christin, additional, Schug, Mariah G., additional, Schulreich, Stefan, additional, Shreedhar, Ganga, additional, Shuman, Eric, additional, Sivan, Smadar, additional, Sjåstad, Hallgeir, additional, Soliman, Meikel, additional, Soud, Katia, additional, Spampatti, Tobia, additional, Sparkman, Gregg, additional, Spasovski, Ognen, additional, Stanley, Samantha K., additional, Stern, Jessica A., additional, Strahm, Noel, additional, Suko, Yasushi, additional, Sul, Sunhae, additional, Syropoulos, Stylianos, additional, Taylor, Neil C., additional, Tedaldi, Elisa, additional, Tinghög, Gustav, additional, Huynh, Luu Duc Toan, additional, Travaglino, Giovanni Antonio, additional, Tsakiris, Manos, additional, Tüter, İlayda, additional, Tyrala, Michael, additional, Uluğ, Özden Melis, additional, Urbanek, Arkadiusz, additional, Valko, Danila, additional, van der Linden, Sander, additional, van Schie, Kevin, additional, van Stekelenburg, Aart, additional, Vanags, Edmunds, additional, Västfjäll, Daniel, additional, Vesely, Stepan, additional, Vintr, Jáchym, additional, Vranka, Marek, additional, Wanguche, Patrick Otuo, additional, Willer, Robb, additional, Wojcik, Adrian Dominik, additional, Xu, Rachel, additional, Yadav, Anjali, additional, Zawisza, Magdalena, additional, Zhao, Xian, additional, Zhao, Jiaying, additional, Żuk, Dawid, additional, and Van Bavel, Jay J., additional

Published
2024
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11. Acute stress reduces effortful prosocial behaviour

Author

Forbes, Paul AG, primary, Aydogan, Gökhan, additional, Braunstein, Julia, additional, Todorova, Boryana, additional, Wagner, Isabella C, additional, Lockwood, Patricia L, additional, Apps, Matthew AJ, additional, Ruff, Christian C, additional, and Lamm, Claus, additional

Published
2024
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13. Acute stress reduces effortful prosocial behaviour

Author

Forbes, Paul A. G., primary, Aydogan, Gökhan, additional, Braunstein, Julia, additional, Todorova, Boryana, additional, Wagner, Isabella C., additional, Lockwood, Patricia L., additional, Apps, Matthew A. J., additional, Ruff, Christian C., additional, and Lamm, Claus, additional

Published
2023
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14. Music for autism: a protocol for an international randomized crossover trial on music therapy for children with autism

Author

Ruiz, Marianna, primary, Groessing, Alexander, additional, Guran, Alexandrina, additional, Koçan, Asena U., additional, Mikus, Nace, additional, Nater, Urs M., additional, Kouwer, Karlijn, additional, Posserud, Maj-Britt, additional, Salomon-Gimmon, Maayan, additional, Todorova, Boryana, additional, Wagner, Isabella C., additional, Gold, Christian, additional, Silani, Giorgia, additional, and Specht, Karsten, additional

Published
2023
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15. Design and implementation of a replication study: The Music for Autism (M4A) binational assessor-blinded randomised crossover trial

Author

Gold, Christian, primary, Groessing, Alexander, additional, Ruiz, Marianna, additional, Guran, Alexandrina, additional, Koçan, Asena, additional, Kouwer, Karlijn, additional, Mikus, Nace, additional, Nater, Urs, additional, Posserud, Maj-Britt, additional, Salomon-Gimmon, Maayan, additional, Todorova, Boryana, additional, Wagner, Isabella, additional, Silani, Giorgia, additional, and Specht, Karsten, additional

Published
2023
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16. Acute stress reduces effortful prosocial behaviour

Author

Forbes, Paul, primary, Aydogan, Gökhan, additional, Braunstein, Julia Therese, additional, Todorova, Boryana, additional, Wagner, Isabella, additional, Lockwood, Patricia, additional, Apps, Matthew A J, additional, Ruff, Christian Carl, additional, and Lamm, Claus, additional

Published
2022
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18. Climate change beliefs and self-benefitting vs pro-environmental behavior

Author

Todorova, Boryana, Doell, Kimberly, Zhang, Lei, Forbes, Paul, Pahl, Sabine, and Lamm, Claus

Subjects
Other Psychology, FOS: Psychology, climate change, Social Psychology, pro-environmental behavior, Environmental Studies, Life Sciences, Psychology, decision-making, Public Affairs, Public Policy and Public Administration, Social and Behavioral Sciences, climate change belief, Environmental Policy
Abstract

Reduction of greenhouse gas emissions is the single most crucial factor for mitigating climate change. https://www.un.org/en/climatechange/science/key-findings. Many actions related to reducing one’s own emissions are time-consuming and effortful (e.g. walking instead of taking the car, switching to a green energy supplier etc.). Little is known about how people discount the benefit to the environment by the amount of time and effort required of them. We will use two tasks where people can win money for themselves or for an environmental organization working on CO2 reductions by investing either 1) their time (operationalized as a waiting period) or 2) effort (operationalized as a hand grip force on a force transducer). By systematically varying the amount of time or effort, we can investigate (and quantify) how these costs influence the decision-making process (deciding when it is worth it to invest your time or effort to act pro-environmental or respectively to benefit yourself). Importantly, the decisions are neither hypothetical nor uncertain, as the participants are indeed winning money for themselves or for CO2 reduction by investing their time and effort. Unfortunately, to the best of our knowledge there has been no research comparing self-benefitting to pro-environmental decision-making, so our theoretisizing has been inspired by literature in the prosocial domain. We expect that participants will be more willing to invest their time and effort into benefitting themselves than the environment. These expectations are based on literature on financial prosocial actions (e.g. for Lockwood et al., 2017) & economic theories (e.g. utility maximization principle). The alternative hypothesis is based on research in the field of moral prosocial decision-making, especially harm prevention: it could be that people are more willing to invest time and effort in benefitting the environment than themselves, if they see these acts as a moral obligation. The low-cost hypothesis (Diekmann & Preisendörfer, 1992) suggests that attitudes explain behavior better when cost is low. When the cost is higher, people fail to act in accordance to their attitudes. To the best of our knowledge, this hypothesis has not been tested experimentally by systematically varying the degrees of time and effort required for certain behavior. Therefore, we want to test the effect of climate change key beliefs (measured by a questionnaire) on effortful and time-consuming decision-making for the benefit of the environment, as well as on environmental policy support. Therefore, the main objective of the present project is to answer the following research questions: (1) How is the benefit to the environment discounted by the time and effort required? (2) How do self vs environment-benefitting decision-making differ? (3) How does this relate to individual differences in climate change beliefs?

Published
2022
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20. Socio-cognitive training impacts emotional and perceptual self-salience but not self-other distinction

Author

UCL - SSH/IPSY - Psychological Sciences Research Institute, UCL - SSH/IACS - Institute of Analysis of Change in Contemporary and Historical Societies, Bukowski, Henryk, Todorova, Boryana, Boch, Magdalena, Silani, Giorgia, Lamm, Claus, UCL - SSH/IPSY - Psychological Sciences Research Institute, UCL - SSH/IACS - Institute of Analysis of Change in Contemporary and Historical Societies, Bukowski, Henryk, Todorova, Boryana, Boch, Magdalena, Silani, Giorgia, and Lamm, Claus

Abstract

Training to inhibit imitative tendencies has been shown to reduce self-other interferences in both automatic imitation and perspective taking, suggesting that an enhancement of self-other distinction is transferrable from the motor to the cognitive domain. This study examined whether socio-cognitive training specifically enhances self-other distinction, or rather modulates self-salience, that is, the relative attentional priority of information pertaining to the self-perspective over information pertaining to the other person's perspective. Across two experiments, participants trained on one day to either imitate, inhibit imitation, inhibit control stimuli, or they were imitated. On the following day they completed a visuo-tactile affective perspective-taking paradigm measuring both self-other distinction and emotional self-salience, and a shape matching paradigm measuring perceptual self-salience. Results indicate no significant or consistent impact of training on self-other distinction performance, but reveal an increased emotional and perceptual self-salience following training to inhibit imitative tendencies. Together, these findings raise the question whether socio-cognitive training improves performance via enhanced self-other distinction, and invite to consider self-salience as a complementary angle to explain the past, present, and future findings on self-other distinction.

Published
2021

21. Interaction of single nucleotide polymorphisms in ADRB2, ADRB3, TNF, IL6, IGF1R, LIPC, LEPR, and GHRL with physical activity on the risk of type 2 diabetes mellitus and changes in characteristics of the metabolic syndrome: The Finnish Diabetes Prevention Study

Author

Kilpeläinen, TuomasO., Lakka, TimoA., Laaksonen, DavidE., Mager, Ursula, Salopuro, Titta, Kubaszek, Agata, Todorova, Boryana, Laukkanen, Olli, Lindström, Jaana, Eriksson, JohanG., Hämäläinen, Helena, Aunola, Sirkka, Ilanne-Parikka, Pirjo, Keinänen-Kiukaanniemi, Sirkka, Tuomilehto, Jaako, Laakso, Markku, and Uusitupa, Matti

Published
2008
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22. Type 2 diabetes whole-genome association study in four populations: the DiaGen consortium

Author

Salonen, Jukka T., Aalto, Juha-Matti, Pirskanen, Mia, Kaikkonen, Jari, Todorova, Boryana, Uimari, Pekka, Hypponen, Jelena, Korhonen, Veli-Pekka, Asikainen, Janne, Devine, Christopher, Tuomainen,Tomi-Pekka, Leudemann, Jan, Nauck, Matthias, Kerner, Wolfgang, Stephans, Richard H., New, John P., Ollier, William E., Gibson, Martin, Payton, Antony, Horan, Michael A., Pendleton, Neil, Mahoney, Walt, Meyre, David, Delplanque, Jerome, Froguel, Philippe, Luzatto, Oren, Yakir, Benjamim, and Darvasi, Ariel

Subjects
Type 2 diabetes -- Genetic aspects, Type 2 diabetes -- Causes of, Multifactorial diseases -- Genetic aspects, Biological sciences
Abstract

The article describes about the type 2 diabetes (T2D), which is a common, polygenic chronic disease with high heretibility.

Published
2007

26. Interaction of single nucleotide polymorphisms in ADRB2, ADRB3, TNF, IL6, IGF1R, LIPC, LEPR, and GHRL with physical activity on the risk of type 2 diabetes mellitus and changes in characteristics of the metabolic syndrome:The Finnish Diabetes Prevention Study

Author

Oskari Kilpeläinen, Tuomas, Lakka, Timo A, Laaksonen, David E, Mager, Ursula, Salopuro, Titta, Kubaszek, Agata, Todorova, Boryana, Laukkanen, Olli, Lindström, Jaana, Eriksson, Johan G, Hämäläinen, Helena, Aunola, Sirkka, Ilanne-Parikka, Pirjo, Keinänen-Kiukaanniemi, Sirkka, Tuomilehto, Jaako, Laakso, Markku, Uusitupa, Matti, Oskari Kilpeläinen, Tuomas, Lakka, Timo A, Laaksonen, David E, Mager, Ursula, Salopuro, Titta, Kubaszek, Agata, Todorova, Boryana, Laukkanen, Olli, Lindström, Jaana, Eriksson, Johan G, Hämäläinen, Helena, Aunola, Sirkka, Ilanne-Parikka, Pirjo, Keinänen-Kiukaanniemi, Sirkka, Tuomilehto, Jaako, Laakso, Markku, and Uusitupa, Matti

Abstract

Single nucleotide polymorphisms (SNPs) in the ADRB2, ADRB3, TNF, IL6, IGF1R, LIPC, LEPR, and GHRL genes were associated with the conversion from impaired glucose tolerance (IGT) to type 2 diabetes mellitus (T2D) in the Finnish Diabetes Prevention Study (DPS). In this study, we determined whether polymorphisms in these genes modified the effect of changes in physical activity (PA) on the risk of T2D in the DPS. Moreover, we assessed whether the polymorphisms modified the effect of changes in PA on changes in measures of body fat, serum lipids, and blood pressure during the first year of the follow-up of the DPS. Overweight subjects with IGT (n = 487) were followed for an average of 4.1 years, and PA was assessed annually with a questionnaire. The interactions of the polymorphisms with changes in total and moderate-to-vigorous PA on the conversion to T2D during the 4.1-year follow-up were assessed using Cox regression with adjustments for the other components of the intervention (dietary changes, weight reduction). Univariate analysis of variance was used to assess interactions on changes in continuous variables during the first year of the follow-up. No interaction between the polymorphisms and PA on the conversion to T2D was found. The Leu72Met (rs696217) polymorphism in GHRL modified the effect of moderate-to-vigorous PA on changes in weight and waist circumference, the -501A/C (rs26802) polymorphism in GHRL modified the effect of total and moderate-to-vigorous PA on change in high-density lipoprotein cholesterol, and the Lys109Arg (rs1137100) polymorphism in LEPR modified the effect of total PA on change in blood pressure. In conclusion, genetic variation may modify the magnitude of the beneficial effects of PA on characteristics of the metabolic syndrome in persons with IGT.

Published
2008

29. ИНФОРМАЦИОННА СИГУРНОСТ В СИСТЕМИТЕ ЗА ЕЛЕКТРОННА ТЪРГОВИЯ В БЪЛГАРИЯ

Author

Popov, Veselin, Emilova, Petya, Dachev, Petar, Tairov, Iskren, Todorova, Boryana, and Borisov, Tsvetelin

Subjects
information security, стратегия за защита, electronic commerce, protection strategy, information security threats, заплахи за информационната сигурност, електронна търговия, информационна сигурност
Abstract

Осигуряването на информационната безопасност е едно от големите предизвикателства към съвременните информационни и комуникационни технологии. За решаването на проблемите в това направление е необходимо организиранена цялостен и з адълбочен анализ на всички реални и потенциални заплахи и на тази основа избор и разработване на цялостно решение. Обект на изследване в настоящата студия са системите за електронна търговия в българските бизнес организации, а предмет – политиките, стратегиите, подходите, методите, техниките и технологиите за постигане на високо ниво на сигурност на тези системи. Основната цел на настоящата студия е да бъде доказана тезата, че ефи- касната защита в електронната търговия е многопластова и трябва да отчита новите технологии, политиките и процедурите, законите и индустриалните стандарти. Задачите, които решаваме за постигане на поставената цел, са: представяне на резултатите от изследване на текущото състояние на сигурността в системите за електронна търговия в българските бизнес организации; дефиниране на проблемите на информационната сигурност в системите за електронна търговия; представяне на стратегия и технологии за противодействие на тези заплахи. The provision of information security is one of the greatest challenges that modern information and communication technologies face. To solve the problems in this area it is necessary to perform a complete and profound analysis of all real and potential threats and, on this basis, to choose and develop a complete solution. The object of study are the e-commerce systems in the Bulgarian business organizations and the subject of study are the policies, strategies, approaches, methods, techniques and technologies to achieve a high level of security of these systems. The main goal of this study is to prove the thesis statement that effective protection in e-commerce is multi-layered and the new technologies, policies and procedures, laws and industry standards have to be taken into account. The tasks to achieve the goal include: presenting the results of a survey of the current state of ecommerce systems security in the Bulgarian business organizations; defining the problems of information security in e-commerce systems; and presenting a strategy and technology to counter these threats.

30. Addressing climate change with behavioral science: a global intervention tournament in 63 countries

Author

Vlasceanu, Madalina, Doell, Kimberly C., Bak-Coleman, Joseph b., Todorova, Boryana, Berkebile-Weinberg, Michael M., Grayson, Samantha j., Patel, Yash, Goldwert, Danielle, Pei, Yifei, Chakroff, Alek, Pronizius, Ekaterina, Van den broek, Karlijn l., Vlasceanu, Denisa, Constantino, Sara, Morais, Michael J., Schumann, Philipp, Rathje, Steve, Fang, Ke, Aglioti, Salvatore maria, Alfano, Mark, Alvarado-Yepez, Andy J., Andersen, Angélica, Anseel, Frederik, Apps, Matthew A. J., Asadli, Chillar, Awuor, Fonda Jane, Azevedo, Flavio, Basaglia, Piero, Bélanger, Jocelyn J., Berger, Sebastian, Bertin, Paul, Białek, Michał, Bialobrzeska, Olga, Blaya-Burgo, Michelle, Bleize, Daniëlle N. M., Bø, Simen, Boecker, Lea, Boggio, Paulo S., Borau, Sylvie, Bos, Björn, Bouguettaya, Ayoub, Brauer, Markus, Brick, Cameron, Brik, Tymofii, Briker, Roman, Brosch, Tobias, Buchel, Ondrej, Buonauro, Daniel, Butalia, Radhika, Carvacho, Héctor, Chamberlain, Sarah A. E., Chan, Hang-Yee, Chow, Dawn, Chung, Dongil, Cian, Luca, Cohen-Eick, Noa, Contreras-Huerta, Luis sebastian, Contu, Davide, Cristea, Vladimir, Cutler, Jo, D'ottone, Silvana, De keersmaecker, Jonas, Delcourt, Sarah, Delouvée, Sylvain, Diel, Kathi, Douglas, Benjamin d., Drupp, Moritz a., Dubey, Shreya, Ekmanis, Jānis, Elbaek, Christian t., Elsherif, Mahmoud, Engelhard, Iris m., Escher, Yannik a., Etienne, Tom W., Farage, Laura, Farias, Ana Rita, Feuerriegel, Stefan, Findor, Andrej, Freira, Lucia, Friese, Malte, Gains, Neil philip, Gallyamova, Albina, Geiger, Sandra j., Genschow, Oliver, Gjoneska, Biljana, Gkinopoulos, Theofilos, Goldberg, Beth, Goldenberg, Amit, Gradidge, Sarah, Grassini, Simone, Gray, Kurt, Grelle, Sonja, Griffin, Siobhán m., Grigoryan, Lusine, Grigoryan, Ani, Grigoryev, Dmitry, Gruber, June, Guilaran, Johnrev, Hadar, Britt, Hahnel, Ulf j.j., Halperin, Eran, Harvey, Annelie j., Haugestad, Christian a. p., Herman, Aleksandra M., Hershfield, Hal E., Himichi, Toshiyuki, Hine, Donald W., Hofmann, Wilhelm, Howe, Lauren, Huaman-Chulluncuy, Enma t., Huang, Guanxiong, Ishii, Tatsunori, Ito, Ayahito, Jia, Fanli, Jost, John T., Jovanović, Veljko, Jurgiel, Dominika, Kácha, Ondřej, Kankaanpää, Reeta, Kantorowicz, Jaroslaw, Kantorowicz-Reznichenko, Elena, Kaplan mintz, Keren, Kaya, Ilker, Kaya, Ozgur, Khachatryan, Narine, Klas, Anna, Klein, Colin, Klöckner, Christian a., Koppel, Lina, Kosachenko, Alexandra i., Kothe, Emily J., Krebs, Ruth, Krosch, Amy R., Krouwel, Andre P. M., Kyrychenko, Yara, Lagomarsino, Maria, Lamm, Claus, Lange, Florian, Lee cunningham, Julia, Lees, Jeffrey, Leung, Tak yan, Levy, Neil, Lockwood, Patricia l., Longoni, Chiara, López ortega, Alberto, Loschelder, David D., Lu, Jackson G., Luo, Yu, Luomba, Joseph, Lutz, Annika E., Majer, Johann M., Markowitz, Ezra, Marsh, Abigail A., Mascarenhas, Karen Louise, Mbilingi, Bwambale, Mbungu, Winfred, Mchugh, Cillian, Meijers, Marijn H. C., Mercier, Hugo, Mhagama, Fenant laurent, Michalakis, Katerina, Mikus, Nace, Milliron, Sarah, Mitkidis, Panagiotis, Monge-Rodríguez, Fredy s., Mora, Youri l., Moreau, David, Motoki, Kosuke, Moyano, Manuel, Mus, Mathilde, Navajas, Joaquin, Nguyen, Tam Luong, Nguyen, Dung Minh, Nguyen, Trieu, Niemi, Laura, Nijssen, Sari R. R., Nilsonne, Gustav, Nitschke, Jonas P., Nockur, Laila, Okura, Ritah, Öner, Sezin, Özdoğru, Asil ali, Palumbo, Helena, Panagopoulos, Costas, Panasiti, Maria serena, Pärnamets, Philip, Paruzel-Czachura, Mariola, Pavlov, Yuri g., Payán-Gómez, César, Pearson, Adam r., Pereira da costa, Leonor, Petrowsky, Hannes m., Pfattheicher, Stefan, Pham, Nhat Tan, Ponizovskiy, Vladimir, Pretus, Clara, Rêgo, Gabriel g., Reimann, Ritsaart, Rhoads, Shawn A., Riano-Moreno, Julian, Richter, Isabell, Röer, Jan philipp, Rosa-Sullivan, Jahred, Ross, Robert m., Sabherwal, Anandita, Saito, Toshiki, Sarrasin, Oriane, Say, Nicolas, Schmid, Katharina, Schmitt, Michael T., Schoenegger, Philipp, Scholz, Christin, Schug, Mariah g., Schulreich, Stefan, Shreedhar, Ganga, Shuman, Eric, Sivan, Smadar, Sjåstad, Hallgeir, Soliman, Meikel, Soud, Katia, Spampatti, Tobia, Sparkman, Gregg, Spasovski, Ognen, Stanley, Samantha K., Stern, Jessica A., Strahm, Noel, Suko, Yasushi, Sul, Sunhae, Syropoulos, Stylianos, Taylor, Neil C., Tedaldi, Elisa, Tinghög, Gustav, Huynh, Luu duc toan, Travaglino, Giovanni antonio, Tsakiris, Manos, Tüter, İlayda, Tyrala, Michael, Uluğ, Özden melis, Urbanek, Arkadiusz, Valko, Danila, Van der linden, Sander, Van schie, Kevin, Van stekelenburg, Aart, Vanags, Edmunds, Västfjäll, Daniel, Vesely, Stepan, Vintr, Jáchym, Vranka, Marek, Wanguche, Patrick otuo, Willer, Robb, Wojcik, Adrian dominik, Xu, Rachel, Yadav, Anjali, Zawisza, Magdalena, Zhao, Xian, Zhao, Jiaying, Żuk, Dawid, Van bavel, Jay j., Vlasceanu, Madalina, Doell, Kimberly C., Bak-Coleman, Joseph b., Todorova, Boryana, Berkebile-Weinberg, Michael M., Grayson, Samantha j., Patel, Yash, Goldwert, Danielle, Pei, Yifei, Chakroff, Alek, Pronizius, Ekaterina, Van den broek, Karlijn l., Vlasceanu, Denisa, Constantino, Sara, Morais, Michael J., Schumann, Philipp, Rathje, Steve, Fang, Ke, Aglioti, Salvatore maria, Alfano, Mark, Alvarado-Yepez, Andy J., Andersen, Angélica, Anseel, Frederik, Apps, Matthew A. J., Asadli, Chillar, Awuor, Fonda Jane, Azevedo, Flavio, Basaglia, Piero, Bélanger, Jocelyn J., Berger, Sebastian, Bertin, Paul, Białek, Michał, Bialobrzeska, Olga, Blaya-Burgo, Michelle, Bleize, Daniëlle N. M., Bø, Simen, Boecker, Lea, Boggio, Paulo S., Borau, Sylvie, Bos, Björn, Bouguettaya, Ayoub, Brauer, Markus, Brick, Cameron, Brik, Tymofii, Briker, Roman, Brosch, Tobias, Buchel, Ondrej, Buonauro, Daniel, Butalia, Radhika, Carvacho, Héctor, Chamberlain, Sarah A. E., Chan, Hang-Yee, Chow, Dawn, Chung, Dongil, Cian, Luca, Cohen-Eick, Noa, Contreras-Huerta, Luis sebastian, Contu, Davide, Cristea, Vladimir, Cutler, Jo, D'ottone, Silvana, De keersmaecker, Jonas, Delcourt, Sarah, Delouvée, Sylvain, Diel, Kathi, Douglas, Benjamin d., Drupp, Moritz a., Dubey, Shreya, Ekmanis, Jānis, Elbaek, Christian t., Elsherif, Mahmoud, Engelhard, Iris m., Escher, Yannik a., Etienne, Tom W., Farage, Laura, Farias, Ana Rita, Feuerriegel, Stefan, Findor, Andrej, Freira, Lucia, Friese, Malte, Gains, Neil philip, Gallyamova, Albina, Geiger, Sandra j., Genschow, Oliver, Gjoneska, Biljana, Gkinopoulos, Theofilos, Goldberg, Beth, Goldenberg, Amit, Gradidge, Sarah, Grassini, Simone, Gray, Kurt, Grelle, Sonja, Griffin, Siobhán m., Grigoryan, Lusine, Grigoryan, Ani, Grigoryev, Dmitry, Gruber, June, Guilaran, Johnrev, Hadar, Britt, Hahnel, Ulf j.j., Halperin, Eran, Harvey, Annelie j., Haugestad, Christian a. p., Herman, Aleksandra M., Hershfield, Hal E., Himichi, Toshiyuki, Hine, Donald W., Hofmann, Wilhelm, Howe, Lauren, Huaman-Chulluncuy, Enma t., Huang, Guanxiong, Ishii, Tatsunori, Ito, Ayahito, Jia, Fanli, Jost, John T., Jovanović, Veljko, Jurgiel, Dominika, Kácha, Ondřej, Kankaanpää, Reeta, Kantorowicz, Jaroslaw, Kantorowicz-Reznichenko, Elena, Kaplan mintz, Keren, Kaya, Ilker, Kaya, Ozgur, Khachatryan, Narine, Klas, Anna, Klein, Colin, Klöckner, Christian a., Koppel, Lina, Kosachenko, Alexandra i., Kothe, Emily J., Krebs, Ruth, Krosch, Amy R., Krouwel, Andre P. M., Kyrychenko, Yara, Lagomarsino, Maria, Lamm, Claus, Lange, Florian, Lee cunningham, Julia, Lees, Jeffrey, Leung, Tak yan, Levy, Neil, Lockwood, Patricia l., Longoni, Chiara, López ortega, Alberto, Loschelder, David D., Lu, Jackson G., Luo, Yu, Luomba, Joseph, Lutz, Annika E., Majer, Johann M., Markowitz, Ezra, Marsh, Abigail A., Mascarenhas, Karen Louise, Mbilingi, Bwambale, Mbungu, Winfred, Mchugh, Cillian, Meijers, Marijn H. C., Mercier, Hugo, Mhagama, Fenant laurent, Michalakis, Katerina, Mikus, Nace, Milliron, Sarah, Mitkidis, Panagiotis, Monge-Rodríguez, Fredy s., Mora, Youri l., Moreau, David, Motoki, Kosuke, Moyano, Manuel, Mus, Mathilde, Navajas, Joaquin, Nguyen, Tam Luong, Nguyen, Dung Minh, Nguyen, Trieu, Niemi, Laura, Nijssen, Sari R. R., Nilsonne, Gustav, Nitschke, Jonas P., Nockur, Laila, Okura, Ritah, Öner, Sezin, Özdoğru, Asil ali, Palumbo, Helena, Panagopoulos, Costas, Panasiti, Maria serena, Pärnamets, Philip, Paruzel-Czachura, Mariola, Pavlov, Yuri g., Payán-Gómez, César, Pearson, Adam r., Pereira da costa, Leonor, Petrowsky, Hannes m., Pfattheicher, Stefan, Pham, Nhat Tan, Ponizovskiy, Vladimir, Pretus, Clara, Rêgo, Gabriel g., Reimann, Ritsaart, Rhoads, Shawn A., Riano-Moreno, Julian, Richter, Isabell, Röer, Jan philipp, Rosa-Sullivan, Jahred, Ross, Robert m., Sabherwal, Anandita, Saito, Toshiki, Sarrasin, Oriane, Say, Nicolas, Schmid, Katharina, Schmitt, Michael T., Schoenegger, Philipp, Scholz, Christin, Schug, Mariah g., Schulreich, Stefan, Shreedhar, Ganga, Shuman, Eric, Sivan, Smadar, Sjåstad, Hallgeir, Soliman, Meikel, Soud, Katia, Spampatti, Tobia, Sparkman, Gregg, Spasovski, Ognen, Stanley, Samantha K., Stern, Jessica A., Strahm, Noel, Suko, Yasushi, Sul, Sunhae, Syropoulos, Stylianos, Taylor, Neil C., Tedaldi, Elisa, Tinghög, Gustav, Huynh, Luu duc toan, Travaglino, Giovanni antonio, Tsakiris, Manos, Tüter, İlayda, Tyrala, Michael, Uluğ, Özden melis, Urbanek, Arkadiusz, Valko, Danila, Van der linden, Sander, Van schie, Kevin, Van stekelenburg, Aart, Vanags, Edmunds, Västfjäll, Daniel, Vesely, Stepan, Vintr, Jáchym, Vranka, Marek, Wanguche, Patrick otuo, Willer, Robb, Wojcik, Adrian dominik, Xu, Rachel, Yadav, Anjali, Zawisza, Magdalena, Zhao, Xian, Zhao, Jiaying, Żuk, Dawid, and Van bavel, Jay j.

Abstract

Effectively reducing climate change requires marked, global behavior change. However, it is unclear which strategies are most likely to motivate people to change their climate beliefs and behaviors. Here, we tested 11 expert-crowdsourced interventions on four climate mitigation outcomes: beliefs, policy support, information sharing intention, and an effortful tree-planting behavioral task. Across 59,440 participants from 63 countries, the interventions’ effectiveness was small, largely limited to nonclimate skeptics, and differed across outcomes: Beliefs were strengthened mostly by decreasing psychological distance (by 2.3%), policy support by writing a letter to a future-generation member (2.6%), information sharing by negative emotion induction (12.1%), and no intervention increased the more effortful behavior—several interventions even reduced tree planting. Last, the effects of each intervention differed depending on people’s initial climate beliefs. These findings suggest that the impact of behavioral climate interventions varies across audiences and target behaviors.

31. Cardiovascular risk factors in type 2 diabetic patients in Bulgaria.

Author

Kurktschiev DP, Vladimirova-Kitova LG, Todorova BR, Kaikkonen J, and Temelkova-Kurktschiev TS

Subjects
Adult, Aged, Blood Pressure, Bulgaria epidemiology, C-Reactive Protein analysis, Cholesterol blood, Diabetes Mellitus, Type 2 blood, Female, Humans, Male, Metabolic Syndrome epidemiology, Middle Aged, Risk Factors, Smoking adverse effects, Triglycerides blood, Cardiovascular Diseases etiology, Diabetes Mellitus, Type 2 complications
Abstract

Unlabelled: Type 2 diabetes mellitus is associated with an excessively high morbidity and mortality from cardiovascular disease. Macrovascular disease with its complications is the leading cause of death in Bulgaria., Aim of This Study: To examine cardiovascular risk factors in patients with type 2 diabetes., Material and Methods: The study included 556 patients with type 2 diabetes and 575 healthy subjects. All participants filled a questionnaire on medical history, lifestyle and family history and standardised measurements were taken of some of their anthropometric parameters and blood pressure. Venous blood was drawn after an overnight fast for the examination of glucose, lipids, C-reactive protein and other cardiovascular risk factors., Results: Seventy-eight percent of the diabetic subjects had a history of coronary heart disease. The diabetics had significantly higher body mass index (27.1 +/- 4.4 kg/m2 vs. 25.0 +/- 3.8 kg/m2; mean +/- SD), waist circumference (101 +/- 10.2 vs. 87 +/- 8), systolic (131 +/- 12 mm Hg vs. 123 +/- 11) and diastolic blood pressure (85 +/- 9 mm Hg vs. 78 +/- 7), blood glucose (8.4 +/- 2.3 mmol/l vs. 5.4 +/- 0.7), total cholesterol (5.8 +/- 0.78 mmol/l vs. 4.9 +/- 1.0), triglycerides (2.18 +/- 1.02 mmol/l vs. 0.98 +/- 0.60) and C-reactive protein (5.2 +/- 3.9 vs. 3.7 +/- 3.1 mg/l) as well as significantly lower levels of HDL-cholesterol (0.96 +/- 0.28 mmol/l vs. 1.45 +/- 0.47) vs. controls., Conclusions: Our study demonstrates that patients with type 2 diabetes in Bulgaria have significantly increased levels of cardiovascular risk factors, which could explain the excessive cardiovascular mortality of these patients.

Published
2009

32. Prevalence and type of dyslipidaemia in a population at risk for cardiovascular death in Bulgaria.

Author

Temelkova-Kurktschiev TS, Kurktschiev DP, Vladimirova-Kitova LG, Vaklinova I, and Todorova BR

Subjects
Adult, Aged, Aged, 80 and over, Bulgaria epidemiology, Cholesterol, HDL blood, Diabetes Mellitus, Type 2 blood, Diabetes Mellitus, Type 2 complications, Female, Humans, Hypertension blood, Hypertension complications, Male, Middle Aged, Myocardial Infarction blood, Prevalence, Risk Factors, Cardiovascular Diseases mortality, Hypercholesterolemia epidemiology, Hypertriglyceridemia epidemiology
Abstract

Unlabelled: Hypercholesterolaemia, hypertriglyceridaemia and low high-density lipoprotein (HDL) cholesterol are established risk factors of macrovascular disease, which leads to stroke and myocardial infarction and is the leading cause of death in Bulgaria. The AIM of our study was to examine the prevalence and type of hyper/dyslipidaemia in patients with myocardial infarction, hypertension and type 2 diabetes mellitus in Bulgaria., Material and Methods: A total of 1230 subjects were examined who had positive own and family history of acute myocardial infarction (AMI) (n=365), hypertension (n=250), type 2 diabetes mellitus (n=250), or neither of the diseases, healthy controls (n=365). All participants filled a questionnaire on medical history, current medication, lifestyle and family history. They underwent standardised measurements of anthropometric parameters and blood pressure. Venous blood was drawn after an overnight fast to test for atherosclerosis risk factors such as lipids, glucose, etc., Results: Although younger than the controls the patients with history of AMI, hypertension and type 2 diabetes had a significantly higher body mass index and waist circumference, as well as significantly higher blood pressure. Seventy percent of the AMI patients received lipid lowering treatment. Total cholesterol level was higher in all patients groups than that in controls, the difference being statistically significant for the AMI patients. Triglycerides were significantly higher in the AMI and the diabetic group in comparison with the controls. HDL cholesterol was lower in all patients groups than that in the controls, the difference being significant between the controls and patients with history ofAMI and diabetes. Hypercholesterolemia was observed in 69.6% of the AMI patients, 51% of the hypertensive patients, 56% of the diabetics and 36% of the controls; triglycerides level above 1.7 mmol/l was found in 85% of the AMI subjects, 28% of the hypertensive patients, 36% of the diabetic patients and 14% of the controls; and low HDL cholesterol--in 61% of the AMI patients, 21% of the hypertensive patients, 28% of the diabetics and 16% of the controls., Conclusions: Our study demonstrates that hypercholesterolemia, hypertriglyceridemia and low HDL cholesterol are very common in patients with history of myocardial infarction, hypertension and type 2 diabetes in Bulgaria and that treatment of the main cardiovascular risk factors seems to be insufficient in these patients.

Published
2009

33. Pulse pressure is a strong predictor of cardiovascular risk: Data of the risk factors in impaired glucose tolerance for atherosclerosis and diabetes and the Sofia Metabolic Syndrome studies.

Author

Temelkova-Kurktschiev TS, Kurktschiev DP, Vladimirova-Kitova LG, Koehler C, Henkel E, Todorova BR, Schaper F, Fuecker K, and Hanefeld M

Subjects
Adult, Aged, Blood Glucose analysis, Body Mass Index, Bulgaria epidemiology, Carotid Arteries pathology, Coronary Artery Disease diagnosis, Coronary Artery Disease epidemiology, Diabetes Mellitus, Type 2 diagnosis, Diabetes Mellitus, Type 2 epidemiology, Female, Glucose Intolerance diagnosis, Glucose Intolerance epidemiology, Glucose Tolerance Test, Humans, Hypertension diagnosis, Hypertension epidemiology, Male, Middle Aged, Obesity, Predictive Value of Tests, Risk Factors, Blood Pressure, Coronary Artery Disease physiopathology, Diabetes Mellitus, Type 2 physiopathology, Glucose Intolerance physiopathology, Hypertension physiopathology
Abstract

Unlabelled: The aim of the present study was to examine the relationship between pulse pressure (PP), cardiovascular risk factors and intima-media thickness (IMT) in a population at risk for type 2 diabetes and atherosclerosis in Saxony, and to assess the association between PP and history of myocardial infarction in the general population of Bulgaria., Material and Methods: The Risk factors in IGT for Atherosclerosis and Diabetes (RIAD) study included 1139 subjects, aged 40-70 years, with a family history of type 2 diabetes, obesity and/or hyper/dyslipoproteinemia. The SMS study included 1018 subjects (> 14 years of age) from the general population of Bulgaria., Results: In RIAD study, PP was significantly correlated with age, plasma glucose, body mass index, microalbuminuria, triglycerides, waist-to-hip ratio, plasminogen activator inhibitor, total cholesterol, free fatty acids, leucocytes count and HDL-cholesterol (inversely). PP was also significantly correlated with carotid IMT. In multivariate analysis PP was an independent determinant of IMT. In the Sofia Metabolic Syndrome (SMS) study PP was significantly correlated with age, body mass index, waist circumference and fasting glucose and was an independent significant determinant of history of myocardial infarction., Conclusions: PP was an important cardiovascular risk factor both in a risk population for type 2 diabetes and atherosclerosis in Saxony and in the general population of Bulgaria.

Published
2009

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