703,648 results on '"To, Janet"'
Search Results
2. Generative AI as a Playful yet Offensive Tourist: Exploring Tensions Between Playful Features and Citizen Concerns in Designing Urban Play
- Author
-
Hung, Peng-Kai, Huang, Janet Yi-Ching, Wensveen, Stephan, and Liang, Rung-Huei
- Subjects
Computer Science - Human-Computer Interaction - Abstract
Play is pivotal in fostering the emotional, social, and cultural dimensions of urban spaces. While generative AI (GAI) potentially supports playful urban interaction, a balanced and critical approach to the design opportunities and challenges is needed. This work develops iWonder, an image-to-image GAI tool engaging fourteen designers in urban explorations to identify GAI's playful features and create design ideas. Fourteen citizens then evaluated these ideas, providing expectations and critical concerns from a bottom-up perspective. Our findings reveal the dynamic interplay between users, GAI, and urban contexts, highlighting GAI's potential to facilitate playful urban experiences through \textit{generative agency}, \textit{meaningful unpredictability}, \textit{social performativity}, and the associated offensive qualities. We propose design considerations to address citizen concerns and the `tourist metaphor' to deepen our understanding of GAI's impact, offering insights to enhance cities' socio-cultural fabric. Overall, this research contributes to the effort to harness GAI's capabilities for urban enrichment.
- Published
- 2025
- Full Text
- View/download PDF
3. Feldman-Cousins' ML Cousin: Sterile Neutrino Global Fits using Simulation-Based Inference
- Author
-
Villarreal, Joshua, Hardin, John M., and Conrad, Janet M.
- Subjects
High Energy Physics - Experiment - Abstract
For many small-signal particle physics analyses, Wilks' theorem, a simplifying assumption that presumes log-likelihood asymptotic normality, does not hold. The most common alternative approach applied in particle physics is a highly computationally expensive procedure put forward by Feldman and Cousins. When many experiments are combined for a global fit to data, deviations from Wilks' theorem are exacerbated, and Feldman-Cousins becomes computationally intractable. We present a novel, machine learning-based procedure that can approximate a full-fledged Bayesian analysis 200 times faster than the Feldman-Cousins method. We demonstrate the utility of this novel method by performing a joint analysis of electron neutrino/antineutrino disappearance data within a single sterile neutrino oscillation framework. Although we present a prototypical simulation-based inference method for a sterile neutrino global fit, we anticipate that similar procedures will be useful for global fits of all kinds, especially those in which Feldman-Cousins is too computationally expensive to use.
- Published
- 2025
4. Gandalf the Red: Adaptive Security for LLMs
- Author
-
Pfister, Niklas, Volhejn, Václav, Knott, Manuel, Arias, Santiago, Bazińska, Julia, Bichurin, Mykhailo, Commike, Alan, Darling, Janet, Dienes, Peter, Fiedler, Matthew, Haber, David, Kraft, Matthias, Lancini, Marco, Mathys, Max, Pascual-Ortiz, Damián, Podolak, Jakub, Romero-López, Adrià, Shiarlis, Kyriacos, Signer, Andreas, Terek, Zsolt, Theocharis, Athanasios, Timbrell, Daniel, Trautwein, Samuel, Watts, Samuel, Wu, Natalie, and Rojas-Carulla, Mateo
- Subjects
Computer Science - Machine Learning ,Computer Science - Artificial Intelligence ,Computer Science - Computation and Language ,Computer Science - Cryptography and Security - Abstract
Current evaluations of defenses against prompt attacks in large language model (LLM) applications often overlook two critical factors: the dynamic nature of adversarial behavior and the usability penalties imposed on legitimate users by restrictive defenses. We propose D-SEC (Dynamic Security Utility Threat Model), which explicitly separates attackers from legitimate users, models multi-step interactions, and rigorously expresses the security-utility in an optimizable form. We further address the shortcomings in existing evaluations by introducing Gandalf, a crowd-sourced, gamified red-teaming platform designed to generate realistic, adaptive attack datasets. Using Gandalf, we collect and release a dataset of 279k prompt attacks. Complemented by benign user data, our analysis reveals the interplay between security and utility, showing that defenses integrated in the LLM (e.g., system prompts) can degrade usability even without blocking requests. We demonstrate that restricted application domains, defense-in-depth, and adaptive defenses are effective strategies for building secure and useful LLM applications. Code is available at \href{https://github.com/lakeraai/dsec-gandalf}{\texttt{https://github.com/lakeraai/dsec-gandalf}}., Comment: Niklas Pfister, V\'aclav Volhejn and Manuel Knott contributed equally
- Published
- 2025
5. Kinesin-driven de-mixing of cytoskeleton composites drives emergent mechanical properties
- Author
-
Sheung, Janet, Gunter, Christopher, Matic, Katarina, Sasanpour, Mehrzad, Ross, Jennifer L., Katira, Parag, Valentine, Megan T., and Robertson-Anderson, Rae M.
- Subjects
Condensed Matter - Soft Condensed Matter - Abstract
The cytoskeleton is an active composite of filamentous proteins that dictates diverse mechanical properties and processes in eukaryotic cells by generating forces and autonomously restructuring itself. Enzymatic motors that act on the comprising filaments play key roles in this activity, driving spatiotemporally heterogeneous mechanical responses that are critical to cellular multifunctionality, but also render mechanical characterization challenging. Here, we couple optical tweezers microrheology and fluorescence microscopy with simulations and mathematical modeling to robustly characterize the mechanics of active composites of actin filaments and microtubules restructured by kinesin motors. We discover that composites exhibit a rich ensemble of force response behaviors, elastic, yielding, and stiffening, with their propensity and properties tuned by motor concentration and strain rate. Moreover, intermediate kinesin concentrations elicit emergent mechanical stiffness and resistance while higher and lower concentrations exhibit softer, more viscous dissipation. We further show that composites transition from well-mixed interpenetrating double-networks of actin and microtubules to de-mixed states of microtubule-rich aggregates surrounded by relatively undisturbed actin phases. It is this de-mixing that leads to the emergent mechanical response, offering an alternate route that composites can leverage to achieve enhanced stiffness through coupling of structure and mechanics.
- Published
- 2025
6. AI Drawing Partner: Co-Creative Drawing Agent and Research Platform to Model Co-Creation
- Author
-
Davis, Nicholas and Rafner, Janet
- Subjects
Computer Science - Human-Computer Interaction - Abstract
This paper describes the AI Drawing Partner, which is a co-creative drawing agent that also serves as a research platform to model co-creation. The AI Drawing Partner is an early example of a quantified co-creative AI system that automatically models the co-creation that happens on the system. The method the system uses to capture this data is based on a new cognitive science framework called co-creative sense-making (CCSM). The CCSM is based on the cognitive theory of enaction, which describes how meaning emerges through interaction with the environment and other people in that environment in a process of sense-making. The CCSM quantifies elements of interaction dynamics to identify sense-making patterns and interaction trends. This paper describes a new technique for modeling the interaction and collaboration dynamics of co-creative AI systems with the co-creative sense-making (CCSM) framework. A case study is conducted of ten co-creative drawing sessions between a human user and the co-creative agent. The analysis includes showing the artworks produced, the quantified data from the AI Drawing Partner, the curves describing interaction dynamics, and a visualization of interaction trend sequences. The primary contribution of this paper is presenting the AI Drawing Partner, which is a unique co-creative AI system and research platform that collaborates with the user in addition to quantifying, modeling, and visualizing the co-creative process using the CCSM framework.
- Published
- 2025
7. A common framework for test ideals, closure operations, and their duals
- Author
-
Epstein, Neil, G., Rebecca R., and Vassilev, Janet
- Subjects
Mathematics - Commutative Algebra - Abstract
Closure operations such as tight and integral closure and test ideals have appeared frequently in the study of commutative algebra. This articles serves as a survey of the authors' prior results connecting closure operations, test ideals, and interior operations via the more general structure of pair operations. Specifically, we describe a duality between closure and interior operations generalizing the duality between tight closure and its test ideal, provide methods for creating pair operations that are compatible with taking quotient modules or submodules, and describe a generalization of core and its dual. Throughout, we discuss how these ideas connect to common constructions in commutative algebra., Comment: 24 pages. Comments welcome
- Published
- 2025
8. Extreme-temperature single-particle heat engine
- Author
-
Message, Molly, Cerisola, Federico, Pritchett, Jonathan D., O'Flynn, Katie, Ren, Yugang, Rashid, Muddassar, Anders, Janet, and Millen, James
- Subjects
Condensed Matter - Statistical Mechanics ,Condensed Matter - Mesoscale and Nanoscale Physics ,Physics - Applied Physics - Abstract
Carnot famously showed that engine operation is chiefly characterised by the magnitude of the temperature ratio $T_\mathrm{h}/T_\mathrm{c}$ between its hot and cold reservoirs. While temperature ratios ranging between $1.3-2.8$ and $2-10$ are common in macroscopic commercial engines and engines operating in the microscopic regime, respectively, the quest is to test thermodynamics at its extremes. Here we present the hottest engine on earth, with temperature ratios as high as $110$. We achieve this by realising an underdamped single-particle engine using a charged microparticle that is electrically levitated under vacuum conditions. Noisy electric fields are used to synthesise reservoir temperatures in excess of $10^7$ K. As a result, giant fluctuations show up in all thermodynamic quantities of the engine, such as heat exchange and efficiency. Moreover, we find that the particle experiences an effective position dependent temperature, which gives rise to dynamics that drastically deviates from that of standard Brownian motion. We develop a theoretical model accounting for the effects of this multiplicative noise and find excellent agreement with the measured dynamics. The high level of control over the presented experimental platform opens the door to emulate the stochastic dynamics of cellular and biological processes, and provides thermodynamic insight required for the development of nanotechnologies.
- Published
- 2025
9. Concentration of ergotropy in many-body systems
- Author
-
Hovhannisyan, Karen V., Simon, Rick P. A., and Anders, Janet
- Subjects
Quantum Physics ,Condensed Matter - Statistical Mechanics - Abstract
Ergotropy -- the maximal amount of unitarily extractable work -- measures the ``charge level'' of quantum batteries. We prove that in large many-body batteries ergotropy exhibits a concentration of measure phenomenon. Namely, the ergotropy of such systems is almost constant for almost all states sampled from the Hilbert--Schmidt measure. We establish this by first proving that ergotropy, as a function of the state, is Lipschitz-continuous with respect to the Bures distance, and then applying Levy's measure concentration lemma. In parallel, we showcase the analogous properties of von Neumann entropy, compiling and adapting known results about its continuity and concentration properties. Furthermore, we consider the situation with the least amount of prior information about the state. This corresponds to the quantum version of the Jeffreys prior distribution -- the Bures measure. In this case, there exist no analytical bounds guaranteeing exponential concentration of measure. Nonetheless, we provide numerical evidence that ergotropy, as well as von Neumann entropy, concentrate also in this case., Comment: 8+4 pages, 2 figures; comments are welcome
- Published
- 2024
10. Harmonic-Induced Plasmonic Resonant Energy Transfer between Metal and Semiconductor Nanoparticles
- Author
-
Yan, Yueming, Spear, Nathan J., Cummings, Adam J., Khusainova, Karina, Macdonald, Janet E., and Haglund, Richard F.
- Subjects
Condensed Matter - Materials Science ,Condensed Matter - Mesoscale and Nanoscale Physics - Abstract
Heterostructures combining two or more metal and/or semiconductor nanoparticles exhibit enhanced upconversion arising from localized surface plasmon resonances (LSPRs). However, coupled plasmon-exciton systems are slowed by excitonic relaxation and metallic multi-plasmon systems are not broadly tunable. Here, we describe a heterostructure in which insulating alumina layers vary separation between CuS and Au nanoparticles, allowing experimental confirmation of the d^(-6) dependence typical of surface-dipole mediated interactions between Au and CuS plasmons, as demonstrated in Lumerical simulations. Transient-absorption spectroscopy shows faster plasmon relaxation in heterostructured Au/CuS (690 fs) than CuS nanoparticles (929 fs), signifying direct energy transfer. Moreover, coupling between the second-harmonic LSPRs of CuS and the fundamental LSPR in Au is evident in nonlinear absorption measurement. This defines a novel harmonic-induced plasmonic resonant energy transfer (HIPRET) dynamic linking the metallic Au plasmon and the broad semiconductor plasmon in CuS. This prototype for tunable, ultrafast plasmonic upconversion exemplifies a strategy for high-efficiency nonlinear nanodevices that have promising applications in photocatalysis, parametric down-conversion and biomedical imaging.
- Published
- 2024
11. Topological nature of edge states for one-dimensional systems without symmetry protection
- Author
-
Zhong, Janet, Wang, Heming, Poddubny, Alexander N, and Fan, Shanhui
- Subjects
Condensed Matter - Mesoscale and Nanoscale Physics ,Quantum Physics - Abstract
We numerically verify and analytically prove a winding number invariant that correctly predicts the number of edge states in one-dimensional, nearest-neighbour (between unit cells), two-band models with any complex couplings and open boundaries. Our winding number uses analytical continuation of the wave-vector into the complex plane and involves two special points on the full Riemann surface band structure that correspond to bulk eigenvector degeneracies. Our invariant is invariant under unitary and similarity transforms. We emphasize that the topological criteria we propose here differ from what is traditionally defined as a topological or trivial phase in symmetryprotected classification studies. It is a broader invariant for our toy model that applies to non-zero energy edge states and its transition does not coincide with the gap closing condition. When the relevant symmetries are applied, our invariant reduces to well-known Hermitian and non-Hermitian symmetry-protected topological invariants., Comment: Supplementary GIFs may be viewed at: https://github.com/janetzhong/Edge-State-Supplementary-GIF
- Published
- 2024
12. Unexpected but informative: What fixation-related potentials tell us about the processing of ambiguous program code
- Author
-
Bergum, Annabelle, Maurer, Anna-Maria, Peitek, Norman, Bader, Regine, Mecklinger, Axel, Demberg, Vera, Siegmund, Janet, and Apel, Sven
- Subjects
Computer Science - Software Engineering - Abstract
As software pervades more and more areas of our professional and personal lives, there is an ever-increasing need to maintain software, and for programmers to be able to efficiently write and understand program code. In the first study of its kind, we analyze fixation-related potentials (FRPs) to explore the online processing of program code patterns that are ambiguous to programmers, but not the computer (so-called atoms of confusion), and their underlying neurocognitive mechanisms in an ecologically valid setting. Relative to unambiguous counterparts in program code, atoms of confusion elicit a late frontal positivity with a duration of about 400 to 700 ms after first looking at the atom of confusion. As the frontal positivity shows high resemblance with an event-related potential (ERP) component found during natural language processing that is elicited by unexpected but plausible words in sentence context, we take these data to suggest that the brain engages similar neurocognitive mechanisms in response to unexpected and informative inputs in program code and in natural language. In both domains, these inputs lead to an update of a comprehender's situation model that is essential for information extraction from a quickly unfolding input.
- Published
- 2024
13. The AI Double Standard: Humans Judge All AIs for the Actions of One
- Author
-
Manoli, Aikaterina, Pauketat, Janet V. T., and Anthis, Jacy Reese
- Subjects
Computer Science - Artificial Intelligence ,Computer Science - Computers and Society ,Computer Science - Emerging Technologies ,Computer Science - Human-Computer Interaction - Abstract
Robots and other artificial intelligence (AI) systems are widely perceived as moral agents responsible for their actions. As AI proliferates, these perceptions may become entangled via the moral spillover of attitudes towards one AI to attitudes towards other AIs. We tested how the seemingly harmful and immoral actions of an AI or human agent spill over to attitudes towards other AIs or humans in two preregistered experiments. In Study 1 (N = 720), we established the moral spillover effect in human-AI interaction by showing that immoral actions increased attributions of negative moral agency (i.e., acting immorally) and decreased attributions of positive moral agency (i.e., acting morally) and moral patiency (i.e., deserving moral concern) to both the agent (a chatbot or human assistant) and the group to which they belong (all chatbot or human assistants). There was no significant difference in the spillover effects between the AI and human contexts. In Study 2 (N = 684), we tested whether spillover persisted when the agent was individuated with a name and described as an AI or human, rather than specifically as a chatbot or personal assistant. We found that spillover persisted in the AI context but not in the human context, possibly because AIs were perceived as more homogeneous due to their outgroup status relative to humans. This asymmetry suggests a double standard whereby AIs are judged more harshly than humans when one agent morally transgresses. With the proliferation of diverse, autonomous AI systems, HCI research and design should account for the fact that experiences with one AI could easily generalize to perceptions of all AIs and negative HCI outcomes, such as reduced trust.
- Published
- 2024
14. Pb transport on Si(111)-(7x7) following tip induced imbalance
- Author
-
Schmidt, Paul Philip, Hartmann, Felix, Faber, Lea, Metzler, Ralf, Anders, Janet, and Hoffmann-Vogel, Regina
- Subjects
Condensed Matter - Mesoscale and Nanoscale Physics ,Condensed Matter - Statistical Mechanics - Abstract
Pb on Si(111)-(7x7) shows surprising nucleation and mass transport dynamics at odds with standard theories. To create local imbalances on stable Pb islands we use the tip of a scanning force microscope. We enforce a short, local contact between the island and our tip. The subsequent island height growth and the local contact potential difference are studied via scanning force microscopy and Kelvin probe force microscopy. Though the island has a large volume increase after the contact, we observe that its surrounding wetting layer shows the same Pb density decrease as the global wetting layer. This indicates a collective density thinning of the wetting layer., Comment: 9 pages, 2 figures in main text and 5 figures in the Appendix; Paper accepted by Physical Review B: https://journals.aps.org/prb/accepted/5e078Yf5E3015a8088ba499754fdeefbd71da71aa
- Published
- 2024
- Full Text
- View/download PDF
15. Gatekeeper Training for Youth Suicide Prevention: A Mixed Method Comparative Analysis of Two Online Programs
- Author
-
Elizabeth Kreuze, Janet York, Dorian A. Lamis, Carolyn Jenkins, Paul Quinnett, Martina Mueller, and Kenneth J. Ruggiero
- Abstract
The overriding aim of this study was to conduct a side-by-side comparative evaluation of two online suicide prevention gatekeeper-training programs: Question, Persuade, Refer (QPR) and Making Educators Partners in Youth Suicide Prevention (MEP). Specific aims included identifying program components, instructional methods, and technology elements that are well received by school personnel and that increase knowledge and self-efficacy. QPR and MEP were directly assessed following levels one and two of Kirkpatrick's Model (i.e., reactions to training, program efficacy), and indirectly assessed at levels three and four (i.e., future gatekeeper behaviors, potential school community impact). QPR and MEP produced positive outcomes with respect to reactions, knowledge, and self-efficacy (i.e., Kirkpatrick levels one and two). MEP and QPR also produced partial support with respect to behavior and impact (i.e., Kirkpatrick levels three and four), given the limited objective data demonstrating consistent application of gatekeeper skills that reduce community suicidal behaviors. Taken together, future research should evaluate inclusion of innovative pedagogical approaches and strategic online classroom design, which may enhance learning motivation, attitudes, and self-efficacy. Research should also objectively evaluate intermediate and longer-term behavioral outcomes to identify population-level impact.
- Published
- 2025
- Full Text
- View/download PDF
16. Student Engagement and Retention of Adult Learners at Community Colleges
- Author
-
Janet Spitzig and Blake J. Renner
- Abstract
This study aimed to examine the relationship between student engagement and student retention of adult learners at community colleges. The relationship between student retention and the five Community College Survey of Student Engagement (CCSSE) student engagement benchmarks (active and collaborative learning, student effort, academic challenge, student-faculty interaction, and support for learners) was examined using binary logistic regression. This study used secondary data from the CCSSE, including 26,326 adult students (25 and older) from the 2019 CCSSE cohort who were credential-seeking at the community college (participants from 588 colleges in 46 states). This study confirmed a positive relationship between student engagement of adult learners at community colleges and student retention. Individually, each of the CCSSE benchmarks increased the likelihood of student retention. As a combined model, academic challenge and support for learners were the only significant benchmarks. This research confirmed that student engagement strategies benefit adult learners at community colleges.
- Published
- 2025
- Full Text
- View/download PDF
17. An Exploration of the Environmental Setting Mothers and Early Adolescent Youth Prefer to Have Conversations about Daily Stressors
- Author
-
Dina Izenstark, Janet Y. Bang, Kelly M. Tu, and Natalee Maynard
- Abstract
Parent-child conversations are impacted by environmental setting. Yet, few studies have considered where mothers and early adolescent youth prefer to have conversations about daily stressors. This study examines where mothers and youth prefer to have conversations about daily stressors, differences in preference based on demographic variables, and why certain environmental settings are preferred. One hundred youth (M = 11.04, 53% boys) and their mothers participated in semi-structured interviews. Findings showed that youth preferred to communicate in their bedroom, the kitchen, and the living room, whereas mothers preferred the kitchen, their child's bedroom, and the car. Using thematic analysis, we found that participants preferred communicating in physically and psychologically comfortable environments, private locations that were away from others, and that they relied on bedtime and mealtime routines to engage in regular conversations. Findings suggest that the place mothers and youth converse matters and may meaningfully impact parent-child conversations about daily stressors.
- Published
- 2025
- Full Text
- View/download PDF
18. Illusionary, Silencing and Civilising -- (Un)Democratic Practices in School Governance
- Author
-
Janet E. Hetherington and Gillian Forrester
- Abstract
Successive British Governments have promulgated policies and initiatives that have not only resulted in the marketisation of education but have, arguably, constructed a democratic deficit in relation to who represents the local in a neoliberal educational context. The article utilises a conceptual framework which encompasses notions of civility and somatic norms as well as evaluative models of deliberative democratic systems. The article illuminates the democratic deficit impact of these policy changes on social groups, such as parents or community members of low socioeconomic status, women and non-white Others. In doing so this research illustrates empirically a democratic deficit which is manifested in the school governance of the Co-operative Aligned Academies Trust (CAAT). It would appear local participatory school governance practices have been systematically disabled due instrumentalist and economistic New Public Management practices and neoliberal reforms. Democracy can be conceived as illusionary in the empowered space and as silencing, civilising and exclusionary (anti) democracy in the public space.
- Published
- 2025
- Full Text
- View/download PDF
19. People who self-reported testing HIV-positive but tested HIV-negative: A multi-country puzzle of data, serology, and ethics, 2015-2021
- Author
-
Metz, Melissa, Among, Vivian Hope, Dzinamarira, Tafadzwa, Ussery, Faith, Nkurunziza, Peter, Bahizi, Janet, Biraro, Samuel, Ogollah, Francis M, Musinguzi, Joshua, Kirungi, Wilford, Naluguza, Mary, Mwangi, Christina, Birhanu, Sehin, Nelson, Lisa J, Longwe, Herbert, Winterhalter, Frieda Sara, Voetsch, Andrew C, Parekh, Bharat S, Patel, Hetal K, Duong, Yen T, Bray, Rachel, and Farley, Shannon M
- Published
- 2024
20. Preparing Future Special Education Faculty for Service in Rural Communities
- Author
-
Kera B. Ackerman, Melinda Jones Ault, Ginevra Courtade, Mary Elliott, Tara D. Harmon, Kristie N. Jones, Katherine L. Jordan, Abbi M. Long, Janet Nutt, Kai M. O'Neill, Lorita N. Rowlett, Kate Snider, Rasheeda R. Swain, and Enrika Wright
- Abstract
In this program description, the authors explain how a doctoral-level embedded service-learning opportunity, part of Project PURPLE (Preparing Urban and Rural Personnel as Leaders in Education), a collaborative personnel preparation training program, taught future faculty to meet the needs of urban and rural schools in high-need settings. The collaboration between two large institutions in the U.S. same state offered scholars a unique opportunity to engage in teaching, research, and service across institutions. For the service-learning project, teams of cross-institution scholars partnered with consultants from a regional special education cooperative that provides technical assistance to a large rural geographical area. Eleven scholars completed seven diverse service projects, ranging from training education professionals to engaging caregivers. This description discusses these projects, along with the benefits to the scholars and the regional cooperative. It also explores implications for practice for future personnel preparation collaborations and possible avenues for future research.
- Published
- 2024
- Full Text
- View/download PDF
21. Parent Outreach Efforts Extend the Sustained Benefits of a Preschool Classroom Intervention: Adolescent Follow-Up of a Randomized Controlled Trial
- Author
-
Rebecca Slotkin, Karen L. Bierman, Brenda S. Heinrichs, and Janet A. Welsh
- Abstract
The Research-based Developmentally Informed (REDI) program enriched Head Start classrooms with teacher-delivered curriculum components designed to enhance child social-emotional learning and language-literacy skills. Parents received information about the program via backpack express, including weekly handouts about program topics and three DVDs illustrating REDI interactive strategies and suggesting home learning activities. In addition to effects on child skill acquisition and school performance (reported previously), positive effects emerged on a family-based outcome: parents of children in REDI-enriched classrooms reported higher quality preschool parent-child conversations than parents in the randomized control group (usual practice) classrooms. This study examined the long-term benefits associated with intervention-related improvements in preschool conversations. The original sample included 356 children (58% White, 24% Black, and 18% Latinx; 54% girls, 46% boys); 77% had the high school follow-up data used in this study. Longitudinal GLM analyses documented significant REDI intervention effects on parent-adolescent communication quality (assessed in the 7th and 9th grades) and on parent- and youth-reported high school behavior problems (assessed in 11th grade). Path analyses revealed significant serial mediation from intervention-related improvements in preschool conversations to parent-adolescent communication quality (grades 7-9) to reductions in later youth-reported (but not parent-reported) behavior problems (grade 11). The findings suggest that including "light touch" parent engagement materials with preschool classroom interventions can contribute to long-term program benefits.
- Published
- 2024
- Full Text
- View/download PDF
22. Theorizing Digital Dialogic Comprehension Pedagogy with Rural Primary Teachers: A Relational Praxis of Knowledge, Space, and Time
- Author
-
Janet K. Outlaw and Jill F. Grifenhagen
- Abstract
This grounded theory study explored how primary-grade teachers perceive and enact dialogic English Language Arts (ELA) comprehension pedagogy in the novel context of pandemic-induced digital learning. The study involved nine diverse rural primary teachers teaching digitally during the coronavirus disease pandemic. The researchers followed a constructivist, postmodern orientation to co-construct substantive theory with the knowledge of participating teachers. The researchers conducted two rounds of virtual interviews and collected digital artifacts of ELA comprehension instruction. Qualitative data were analyzed using constant comparative analysis to address teacher perceptions and enactments of digital dialogic comprehension instruction. The emergent substantive theory represents connected, iterative processes of teachers perceiving and enacting dialogic, digital instruction. First, teachers espoused a dialogic stance toward ELA instruction based on their beliefs in various comprehension paradigms, diverse funds of knowledge, and multiplicity of voices in discourse. Relatedly, teachers responded to particularities of virtual contexts, digital discourses, and pandemic times to enact dialogic ELA comprehension instruction through a reconstruction of literacy pedagogies. Implications for research and practice are discussed, including the need for ongoing negotiation of dialogic pedagogy in diverse instructional contexts, to cultivate teachers' dialogic literacy practices in locally and culturally responsive ways.
- Published
- 2024
- Full Text
- View/download PDF
23. A Mathematics Educator Walks into a Physics Class: Identifying Math Skills in Students' Physics Problem-Solving Practices
- Author
-
Janet Bowers, Matthew Anderson, and Kathryn Beckhard
- Abstract
One of the main goals of lower division "service" mathematics courses is to provide STEM-intending students with opportunities to engage in activities and contexts that can support their efforts to apply the mathematical ideas they are learning to successive major courses. The Mathematics Association of America has supported many mathematicians' efforts to ask partner discipline faculty what topics and habits of mind they feel should be covered in mathematics classes to prepare them for their subsequent classes. We add to this work with a twist: Instead of asking physics faculty what they want students to know, we analyzed videos that students in an introductory physics class created so that we could ask ourselves what mathematical practices were most and least prevalent in the students' physics problem-solving efforts. A qualitative analysis of the results, which we present here, indicated that most students were proficient in math practices involving problem setup and that the majority were able to apply mathematical concepts such as trigonometry and the solving of algebraic equations. However, only 44% of the student groups concluded their explanations by discussing answer reasonability and only 18% conducted a unit analysis to determine if their answers were applicable to the context of the problems assigned, even though both of these elements are important components of the overall sensemaking process. This report presents examples that illustrate these results and concludes with implications for teaching both entry-level mathematics and physics courses by modeling productive problem-solving and sensemaking practices.
- Published
- 2024
- Full Text
- View/download PDF
24. A School-Based Evaluation of the FRIENDS Resilience Programs: Implications for Mental Health Concerns in Rural Students
- Author
-
Rebecca A. Schwartz-Mette, Hannah R. Lawrence, Eliot Fearey, Jessica Shankman, Janet Nichols, Joy Walters, Elena Perello, and Susan Smith
- Abstract
The FRIENDS Resilience programs provide cognitive-behavioral skills across the developmental spectrum and can be applied as a universal or selective prevention program. In the current study, we assessed whether, relative to the schools' existing counseling curriculum ("guidance"), FRIENDS improved social skills, problem behaviors, and academic competence in a sample of 650 students in kindergarten, 2nd, 5th, and 7th grade in a rural community in the northeastern United States. Student, parent, and teacher reports were obtained pre-intervention, post-intervention, and 4 months later. Analyses examined FRIENDS as a universal prevention program in the general school population and as a selective intervention for at-risk students (those with elevated existing symptoms). Teachers reported improvements in social skills, problem behaviors, and academic competence, and parents reported improved problem behaviors immediately post-intervention for all students receiving FRIENDS and guidance. However, at-risk students who received FRIENDS experienced significantly greater improvements in teacher-reported problem behaviors compared to those who received guidance. When assessing changes over time once all students had received FRIENDS, teacher-rated social skills and academic competence improved, and student- and parent-rated problem behaviors decreased from pre- to post-FRIENDS and 4-month follow-up. Effects were consistent for the overall sample and at-risk students, with stronger effects for those at-risk. These small yet significant effects of FRIENDS as universal prevention may be more limited relative to usual guidance curriculum, but preventative effects may be enhanced for those students in more immediate need of support. Directions for future evaluation of FRIENDS are discussed.
- Published
- 2024
- Full Text
- View/download PDF
25. Populations Digitally Excluded from Education: Issues, Factors, Contributions and Actions for Policy, Practice and Research in a Post-Pandemic Era
- Author
-
Don Passey, Jean Gabin Ntebutse, Manal Yazbak Abu Ahmad, Janet Cochrane, Simon Collin, Asmaa Ganayem, Elizabeth Langran, Sadaqat Mulla, Maria Mercedes Rodrigo, Toshinori Saito, Miri Shonfeld, and Saunand Somasi
- Abstract
This conceptual paper draws on a wide range of research and policy literature, providing a contemporary view of issues, factors and practices that affect education for digitally excluded populations. Concern for how education for digitally excluded populations can be supported is focal to this paper, with different sections offering key related perspectives. From an analysis of issues, factors and practices, actions for policy, practice and research are identified. Given a key finding that power issues can have major effects on plans, implementation processes and outcomes when addressing needs of education for digitally excluded populations, the paper concludes by offering frameworks to support and enable key discussions, to involve representatives from an excluded population as well as those from policy (government and industry), practitioners (teachers and learners) and researchers.
- Published
- 2024
- Full Text
- View/download PDF
26. Black Americans, Civil Rights and the Roosevelts, 1932–1962 A Special Exhibition at the Franklin D. Roosevelt Presidential Library and Museum Hyde Park, NY, June 3, 2023 - December 31, 2024
- Author
-
Manko, Janet
- Published
- 2024
27. From Pajama Boy to Pepe the Frog: Power, Essentialism, and the Nation-State in the Manosphere
- Author
-
McIntosh, Janet
- Published
- 2025
28. Exploring the Role of Glycine Metabolism in Coronary Artery Disease: Insights from Human Genetics and Mouse Models.
- Author
-
Biswas, Subarna, Hilser, James, Woodward, Nicholas, Wang, Zeneng, Gukasyan, Janet, Nemet, Ina, Schwartzman, William, Huang, Pin, Han, Yi, Fouladian, Zachary, Charugundla, Sarada, Spencer, Neal, Pan, Calvin, Tang, W, Lusis, Aldons, Hazen, Stanley, Hartiala, Jaana, and Allayee, Hooman
- Subjects
Mendelian randomization ,atherosclerosis ,coronary artery disease ,dietary supplementation ,genome-wide association study ,glycine ,mice ,Glycine ,Animals ,Humans ,Coronary Artery Disease ,Genome-Wide Association Study ,Mice ,Male ,Female ,Middle Aged ,Disease Models ,Animal ,Mendelian Randomization Analysis ,Aged ,Atherosclerosis ,Polymorphism ,Single Nucleotide ,Genetic Predisposition to Disease ,Dietary Supplements ,United Kingdom - Abstract
Background: Circulating glycine levels have been associated with reduced risk of coronary artery disease (CAD) in humans but these associations have not been observed in all studies. We evaluated whether the relationship between glycine levels and atherosclerosis was causal using genetic analyses in humans and feeding studies in mice. Methods: Serum glycine levels were evaluated for association with risk of CAD in the UK Biobank. Genetic determinants of glycine levels were identified through a genome-wide association study (GWAS) and used to evaluate the causal relationship between glycine and risk of CAD by Mendelian randomization (MR). A dietary supplementation study was carried out with atherosclerosis-prone apolipoprotein E deficient (ApoE-/-) mice to determine the effects of increased circulating glycine levels on cardiometabolic traits and aortic lesion formation. Results: Among 105,718 UK Biobank subjects, elevated serum glycine levels were associated with significantly reduced risk of prevalent CAD (Quintile 5 vs. Quintile 1 OR = 0.76, 95% CI 0.67-0.87; p < 0.0001) and incident CAD (Quintile 5 vs. Quintile 1 HR = 0.70, 95% CI 0.65-0.77; p < 0.0001) after adjustment for age, sex, ethnicity, anti-hypertensive and lipid-lowering medications, blood pressure, kidney function, and diabetes. A GWAS meta-analysis with 230,947 subjects identified 61 loci for glycine levels, of which 26 were novel. MR analyses provided modest evidence that genetically elevated glycine levels were causally associated with reduced systolic blood pressure and risk of type 2 diabetes, but did not provide significant evidence for an association with decreased risk of CAD. Glycine supplementation in mice had no effects on cardiometabolic traits or atherosclerotic lesion development. Conclusions: While expanding the genetic architecture of glycine metabolism, MR analyses and in vivo feeding studies did not provide evidence that the clinical association of this amino acid with atherosclerosis represents a causal relationship.
- Published
- 2025
29. Social Capital and Cultural Health Capital in Primary Care: The Case of Group Medical Visits.
- Author
-
Thompson-Lastad, Ariana, Harrison, Jessica, and Shim, Janet
- Subjects
Humans ,Social Capital ,Primary Health Care ,Grounded Theory ,United States ,Female ,Male ,Middle Aged ,Adult ,Social Support ,Interviews as Topic ,Qualitative Research ,Shared Medical Appointments - Abstract
This article focuses on an empirical setting that upends the clinician-patient dyadic norm: group medical visits (GMVs), in which multiple patients gather in the same space for medical care, health education and peer support. Our grounded theory analysis draws on participant observation and interviews (N = 53) with patients and staff of GMVs at four safety-net healthcare organisations in the United States. We delineate (1) how group medical visits provide health-focused social networks that facilitate the mobilisation of social capital, (2) how the organisationally embedded relationships that comprise group visits are made possible through extended time that is part of the GMV field and (3) how clinicians have opportunities rarely found in other settings to learn from patients, using knowledge accrued from GMV networks to advance their own skills, thereby converting social capital into provider cultural health capital. GMVs provide a rich empirical site for understanding the ways in which organisational arrangements can shape opportunities for patients and clinicians to cultivate and mobilise social capital and cultural health capital, and in doing so, materially shift experiences of receiving and providing healthcare.
- Published
- 2025
30. Prolonged venous transit is associated with lower odds of excellent recovery after reperfusion in anterior large-vessel occlusion stroke.
- Author
-
Salim, Hamza, Lakhani, Dhairya, Mei, Janet, Luna, Licia, Shahriari, Mona, Hyson, Nathan, Deng, Francis, Dmytriw, Adam, Guenego, Adrien, Urrutia, Victor, Marsh, Elisabeth, Lu, Hanzhang, Xu, Risheng, Leigh, Rich, Wolman, Dylan, Shah, Gaurang, Pulli, Benjamin, Albers, Gregory, Hillis, Argye, Llinas, Rafael, Nael, Kambiz, Wintermark, Max, Heit, Jeremy, Faizy, Tobias, and Yedavalli, Vivek
- Subjects
Acute ischemic stroke (AIS) ,Computed tomography perfusion (CTP) ,Intravenous thrombolysis (IVT) ,Large‐vessel occlusion (LVO) ,Mechanical thrombectomy (MT) ,Prolonged venous transit (PVT) ,Venous outflow (VO) ,Humans ,Male ,Female ,Aged ,Middle Aged ,Ischemic Stroke ,Recovery of Function ,Retrospective Studies ,Reperfusion ,Aged ,80 and over ,Cerebrovascular Circulation ,Treatment Outcome - Abstract
BACKGROUND AND PURPOSE: Acute ischemic stroke due to anterior circulation large-vessel occlusion (AIS-LVO) remains a leading cause of disability despite successful reperfusion therapies. Prolonged venous transit (PVT) has emerged as a potential prognostic imaging biomarker in AIS-LVO. We aimed to investigate whether PVT is associated with a decreased likelihood of excellent functional outcome (modified Rankin Scale [mRS] score of 0-1 at 90 days) after successful reperfusion. METHODS: In our prospectively collected, retrospectively reviewed database, we analyzed data from 104 patients with AIS-LVO who achieved successful reperfusion (modified Thrombolysis in Cerebral Infarction score of 2b/2c/3) between September 2017 and September 2022. PVT was defined as a time to maximum (Tmax) of ≥10 s in the superior sagittal sinus and/or torcula on computed tomography perfusion (CTP) imaging. Patients were categorized into PVT-positive (PVT+) and PVT-negative (PVT-) groups. The primary outcome was excellent functional recovery at 90 days. RESULTS: Of the 104 patients, 30 (29%) were PVT+. Excellent functional outcome was achieved in 38 patients (37%). PVT+ patients had a significantly lower rate of excellent recovery compared to PVT- patients (11% vs. 39%; p
- Published
- 2025
31. Defining the transition from new to normal: a qualitative investigation of the clinical change process.
- Author
-
Silver, Santana, Jones, Kayla, Hook, Kimberly, Crable, Erika, George, Emily, Serwint, Janet, Austad, Kirsten, Walkey, Allan, and Drainoni, Mari-Lynn
- Subjects
Clinical practice change ,Evidence-based practice ,Healthcare delivery ,Implementation science ,Normalization ,Sustainment ,Humans ,Qualitative Research ,Interviews as Topic ,Quality Improvement ,Organizational Innovation ,Female ,Male ,Evidence-Based Practice ,Implementation Science - Abstract
BACKGROUND: Understanding how and when a new evidence-based clinical intervention becomes standard practice is crucial to ensure that healthcare is delivered in alignment with the most up-to-date knowledge. However, rigorous methods are needed to determine when a new clinical practice becomes normalized to the standard of care. To address this gap, this study qualitatively explores how, when, and why a clinical practice change becomes normalized within healthcare organizations. METHODS: We used purposive sampling to recruit clinical leaders who worked in quality improvement and/or implementation science in diverse health contexts. Enrolled participants completed semi-structured interviews around implementing evidence-based practices. Qualitative data was inductively and deductively analyzed, and was guided by a modified version of the Normalization Process Theory (NPT) framework to identify salient themes. Additionally, identified normalization strategies were mapped to the Expert Recommendations for Implementation Change (ERIC) project. RESULTS: A total of 17 individuals were interviewed. Two categories of themes emerged: 1) signals of when a new clinical practice is considered to be normalized within clinical care; and 2) strategies utilized to normalize new clinical innovations. Participants described four key signals for identifying when a novel clinical practice becomes the new normal: 1) integrated seamlessly into existing workflows; 2) scaled across the entire organizational unit; 3) has strong staff buy-in and ownership; and 4) no longer needs monitoring and evaluation to be sustained. Major strategies to normalize new clinical interventions included: 1) taking a patient approach that starts slow and gains momentum; 2) identifying and using methods to gain staff buy-in and ownership; and 3) conducting ongoing measurement of progress towards normalization. CONCLUSIONS: The results offer valuable insight into the indicators that signify when a novel clinical practice becomes normalized, and the strategies employed to facilitate this transition. These findings can inform future research to develop instruments that implementation leaders can use to systematically measure the clinical change process.
- Published
- 2024
32. High school diploma is associated with longer postpartum leukocyte telomere length in a cohort of primarily Latina women.
- Author
-
Sumesh, Dhanya, Lin, Jue, and Wojcicki, Janet
- Abstract
OBJECTIVE: This study investigates correlates of maternal leukocyte telomere length (LTL) in the immediate postpartum period using a cross-sectional study design from an existing prospective longitudinal birth cohort of primarily Latina women. The study focuses on the role of maternal health and dietary habits in pregnancy and maternal education level and LTL at delivery. STUDY DESIGN: Latina mothers were recruited during the immediate postpartum period prior to 24 h at two San Francisco hospitals and dried blood spots were collected for LTL analysis via quantitative polymerase chain reaction (qPCR). We used multivariable linear regression models to determine independent predictors of maternal LTL during the postpartum period. RESULTS: In multivariable regression models, increasing maternal age was associated with shorter LTL during the immediate postpartum period (Coeff - 0.015; p
- Published
- 2024
33. Prevalence and Correlates of Frailty Among Older People With and Without HIV in Rural Uganda.
- Author
-
Mbabazi, Phoebe, Chen, Geoffrey, Ritchie, Christine, Tsai, Alexander, Reynolds, Zahra, Paul, Robert, Seeley, Janet, Tong, Yao, Hoeppner, Susanne, Okello, Samson, Nakasujja, Noeline, Olivieri-Mui, Brianne, Tanner, Jeremy, Saylor, Deanna, Asiimwe, Stephen, Siedner, Mark, and Greene, Meredith
- Subjects
Humans ,Female ,Uganda ,Male ,HIV Infections ,Frailty ,Prevalence ,Middle Aged ,Rural Population ,Aged ,Cohort Studies ,Quality of Life - Abstract
BACKGROUND: The relationship between HIV and frailty, a predictor of poor outcomes in the face of stressors, remains unknown in older people in sub-Saharan Africa. METHODS: We analyzed data from the Quality of Life and Ageing with HIV in Rural Uganda cohort study to estimate the prevalence and correlates of frailty among older people with HIV (PWH) on long-term antiretroviral therapy and among age- and sex-matched HIV-uninfected comparators. Frailty was defined as a self-report of 3 or 4 (and pre-frailty as 1 or 2) of the following phenotypic variables: weight loss, exhaustion, low activity, and slowness. We estimated the prevalence of frailty and prefrailty and fitted logistic regression models to estimate the association between HIV and frailty, adjusting for sociodemographic factors, depression, and other comorbidities. RESULTS: We enrolled 599 participants (49% women) with a mean age of 58 years. PWH had a similar prevalence of frailty (8.1% vs. 10.9%, P = 0.24) but a lower prevalence of prefrailty (54.2% vs. 63.2%, P = 0.03) compared with their HIV-uninfected comparators. In multivariable regression models, people with depression [adjusted odds ratio (AOR) 7.52 (95% CI: 3.67 to 15.40), P < 0.001] and those with ≥1 comorbidities [AOR 3.15 (95% CI: 1.71 to 3.82), P < 0.001] were more likely to be frail. HIV serostatus was not significantly associated with frailty [AOR 0.71 (95% CI: 0.37 to 1.34), P = 0.29]. CONCLUSIONS: Older PWH had a similar prevalence of frailty as those without HIV. These findings call for additional study of the factors that contribute to the robustness of older PWH in sub-Saharan Africa.
- Published
- 2024
34. A multi-institutional study to investigate the sparing effect after whole brain electron FLASH in mice: Reproducibility and temporal evolution of functional, electrophysiological, and neurogenic endpoints
- Author
-
Drayson, Olivia GG, Melemenidis, Stavros, Katila, Nikita, Viswanathan, Vignesh, Kramár, Enikö A, Zhang, Richard, Kim, Rachel, Ru, Ning, Petit, Benoit, Dutt, Suparna, Manjappa, Rakesh, Ashraf, M Ramish, Lau, Brianna, Soto, Luis, Skinner, Lawrie, Yu, Amu S, Surucu, Murat, Maxim, Peter G, Zebadua-Ballasteros, Paola, Wood, Marcelo A, Montay-Gruel, Pierre, Baulch, Janet E, Vozenin, Marie-Catherine, Loo, Billy W, and Limoli, Charles L
- Subjects
Medical and Biological Physics ,Biomedical and Clinical Sciences ,Clinical Sciences ,Physical Sciences ,Oncology and Carcinogenesis ,Neurosciences ,Rare Diseases ,Cancer ,6.5 Radiotherapy and other non-invasive therapies ,Neurological ,Animals ,Mice ,Female ,Reproducibility of Results ,Neurogenesis ,Brain ,Radiotherapy Dosage ,Long-Term Potentiation ,Hippocampus ,Mice ,Inbred C57BL ,Radiotherapy ,FLASH ,Intercomparison ,Neurobehavior ,Electrophysiology ,Neuroinflammation ,Other Physical Sciences ,Oncology & Carcinogenesis ,Clinical sciences ,Oncology and carcinogenesis ,Medical and biological physics - Abstract
Background and purposeUltra-high dose-rate radiotherapy (FLASH) has been shown to mitigate normal tissue toxicities associated with conventional dose rate radiotherapy (CONV) without compromising tumor killing in preclinical models. A prominent challenge in preclinical radiation research, including FLASH, is validating both the physical dosimetry and the biological effects across multiple institutions.Materials and methodsWe previously demonstrated dosimetric reproducibility of two different electron FLASH devices at separate institutions using standardized phantoms and dosimeters. In this study, tumor-free adult female mice were given 10 Gy whole brain FLASH and CONV irradiation at both institutions and evaluated for the reproducibility and temporal evolution of multiple neurobiological endpoints.ResultsFLASH sparing of behavioral performance on novel object recognition (4 months post-irradiation) and of electrophysiologic long-term potentiation (LTP, 5 months post-irradiation) was reproduced between institutions. Differences between FLASH and CONV on the endpoints of hippocampal neurogenesis (Sox2, doublecortin), neuroinflammation (microglial activation), and electrophysiology (LTP) were not observed at early times (48 h to 2 weeks), but recovery of immature neurons by 3 weeks was greater with FLASH.ConclusionIn summary, we demonstrated reproducible FLASH sparing effects on the brain between two different beams at two different institutions with validated dosimetry. FLASH sparing effects on the endpoints evaluated manifested at later but not the earliest time points.
- Published
- 2024
35. Correlates of Sleep Health among Older-Age People with and without HIV in Uganda.
- Author
-
Yoo-Jeong, Moka, Ratnayake, Aneeka, Tong, Yao, Tsai, Alexander, Paul, Robert, Reynolds, Zahra, Ritchie, Christine, Seeley, Janet, Hoeppner, Susanne, Atwiine, Flavia, Okello, Samson, Nakasujja, Noeline, Saylor, Deanna, Greene, Meredith, Asiimwe, Stephen, Tindimwebwa, Edna, Tanner, Jeremy, Olivieri-Mui, Brianne, and Siedner, Mark
- Subjects
Depression ,HIV ,Older Adults ,Sleep ,Uganda ,Humans ,Female ,Male ,Uganda ,Middle Aged ,HIV Infections ,Aged ,Quality of Life ,Depression ,Rural Population ,Sleep Quality ,Sleep Wake Disorders ,Aging ,Cross-Sectional Studies ,Anxiety ,Sleep ,Surveys and Questionnaires ,Loneliness - Abstract
There is a growing population of older people with HIV (PWH) in Uganda. Sleep problems disproportionately affect older people and PWH. This study aimed to estimate correlates of sleep health among older Ugandans (aged ≥ 50 years) with and without HIV, using data from the Quality of Life and Aging with HIV in Rural Uganda Study. We used the Pittsburgh Sleep Quality Index to assess sleep quality, duration, and efficiency. We fitted multivariable linear and logistic regression models to estimate the associations between sleep outcomes and variables selected based on the Senescent Sleep Model: age, HIV serostatus, loneliness, urbanicity, symptoms of depression and anxiety, and perceived stress. Of 556 participants, 271 were PWH and 285 were people without HIV (PWoH). There were no statistically significant differences in sleep outcomes by HIV serostatus. Of the total sample, most reported very good (32.79%) or fairly good sleep quality (49.37%). The mean sleep duration was 6.46 h (SD = 1.74). The mean sleep efficiency was 73.98% (SD = 19.52%) with 36.69% having optimal (≥ 85%) sleep efficiency. A positive depression screen was associated with worse sleep quality (adjusted odds ratio [aOR] = 0.21; 95% CI [0.12, 0.36]), shorter sleep duration (b=-0.44; 95% CI [-0.60, -0.28]), and worse sleep efficiency (aOR = 0.51; 95% CI[0.31, 0.83]). Interventions targeting depression may improve sleep among older Ugandans, independent of HIV serostatus. Longitudinal studies are needed to determine the potential bidirectionality of this relationship and elucidate pathways to support sleep health among older Ugandans.
- Published
- 2024
36. ¿Donde están? Hispanic/Latine inclusion, diversity and representation in the HEALthy Brain and Child Development Study (HBCD).
- Author
-
Anunziata, Florencia, Cisneros, Cynthia, Natale Castillo, Maria, Perez, Alexandra, Rodriguez, Valeria, De La Cruz, Sheila, Estrada, Karla, Durbal, Abigaile, Jaramillo, Mishaska, Enriquez Marquez, Lidia, Nuñez, Janet, Peralta-Carcelen, Myriam, and Lee Wisnowski, Jessica
- Subjects
Early childhood ,HBCD ,Health disparities ,Hispanic/Latine populations ,Longitudinal studies ,Spanish Language and Culture Committee ,Child ,Child ,Preschool ,Female ,Humans ,Brain ,Child Development ,Cultural Diversity ,Hispanic or Latino ,Longitudinal Studies ,Prospective Studies ,United States - Abstract
The HEALthy Brain and Child Development (HBCD) Study, a multi-site prospective longitudinal cohort study, will examine human brain, cognitive, behavioral, social, and emotional development beginning prenatally and planned through early childhood. Central to its mission of reducing health disparities is the establishment of the Spanish Language and Culture Committee (SLCC) within the HBCD framework, a significant step towards demographic representation and inclusivity in research. By addressing linguistic and sociocultural barriers and embracing the diverse identities of Hispanic/Latine individuals nationwide, the SLCC aims to promote inclusion, equity, and representation of all Hispanic/Latine subgroups, a population that has been historically misrepresented in health research. In this paper we describe the role of the SLCC in advocating for Hispanic/Latine families within the study, ensuring their inclusion from inception. This report also provides an overview of the SLCC organization, workflow, challenges and lessons learned thus far to reduce stigma and improve study outcomes, highlighting recruitment and retention strategies for the Hispanic/Latine population, and expanding outreach to promote inclusion across diverse Hispanic/Latine subgroups in the United States.
- Published
- 2024
37. AI and the Future of Work in Africa White Paper
- Author
-
O'Neill, Jacki, Marivate, Vukosi, Glover, Barbara, Karanu, Winnie, Tadesse, Girmaw Abebe, Gyekye, Akua, Makena, Anne, Rosslyn-Smith, Wesley, Grollnek, Matthew, Wayua, Charity, Baguma, Rehema, Maduke, Angel, Spencer, Sarah, Kandie, Daniel, Maari, Dennis Ndege, Mutangana, Natasha, Axmed, Maxamed, Kamau, Nyambura, Adamu, Muhammad, Swaniker, Frank, Gatuguti, Brian, Donner, Jonathan, Graham, Mark, Mumo, Janet, Mbindyo, Caroline, N'Guessan, Charlette, Githinji, Irene, Makhafola, Lesego, Kruger, Sean, Etyang, Olivia, Onando, Mulang, Sevilla, Joe, Sambuli, Nanjira, Mbaya, Martin, Breloff, Paul, Anapey, Gideon M., Mogaleemang, Tebogo L., Nghonyama, Tiyani, Wanyoike, Muthoni, Mbuli, Bhekani, Nderu, Lawrence, Nyabero, Wambui, Alam, Uzma, Olaleye, Kayode, Njenga, Caroline, Sellen, Abigail, Kairo, David, Chabikwa, Rutendo, Abdulhamid, Najeeb G., Kubasu, Ketry, Okolo, Chinasa T., Akpo, Eugenia, Budu, Joel, Karambal, Issa, Berkoh, Joseph, Wasswa, William, Njagwi, Muchai, Burnet, Rob, Ochanda, Loise, de Bod, Hanlie, Ankrah, Elizabeth, Kinyunyu, Selemani, Kariuki, Mutembei, Kiyimba, Kizito, Eleshin, Farida, Madeje, Lillian Secelela, Muraga, Catherine, Nganga, Ida, Gichoya, Judy, Maina, Tabbz, Maina, Samuel, Mercy, Muchai, Ochieng, Millicent, and Nyairo, Stephanie
- Subjects
Computer Science - Human-Computer Interaction ,Computer Science - Artificial Intelligence - Abstract
This white paper is the output of a multidisciplinary workshop in Nairobi (Nov 2023). Led by a cross-organisational team including Microsoft Research, NEPAD, Lelapa AI, and University of Oxford. The workshop brought together diverse thought-leaders from various sectors and backgrounds to discuss the implications of Generative AI for the future of work in Africa. Discussions centred around four key themes: Macroeconomic Impacts; Jobs, Skills and Labour Markets; Workers' Perspectives and Africa-Centris AI Platforms. The white paper provides an overview of the current state and trends of generative AI and its applications in different domains, as well as the challenges and risks associated with its adoption and regulation. It represents a diverse set of perspectives to create a set of insights and recommendations which aim to encourage debate and collaborative action towards creating a dignified future of work for everyone across Africa.
- Published
- 2024
38. Derivational Morphology Reveals Analogical Generalization in Large Language Models
- Author
-
Hofmann, Valentin, Weissweiler, Leonie, Mortensen, David, Schütze, Hinrich, and Pierrehumbert, Janet
- Subjects
Computer Science - Computation and Language ,Computer Science - Artificial Intelligence ,Computer Science - Machine Learning - Abstract
What mechanisms underlie linguistic generalization in large language models (LLMs)? This question has attracted considerable attention, with most studies analyzing the extent to which the language skills of LLMs resemble rules. As of yet, it is not known whether linguistic generalization in LLMs could equally well be explained as the result of analogical processes, which can be formalized as similarity operations on stored exemplars. A key shortcoming of prior research is its focus on linguistic phenomena with a high degree of regularity, for which rule-based and analogical approaches make the same predictions. Here, we instead examine derivational morphology, specifically English adjective nominalization, which displays notable variability. We introduce a new method for investigating linguistic generalization in LLMs: focusing on GPT-J, we fit cognitive models that instantiate rule-based and analogical learning to the LLM training data and compare their predictions on a set of nonce adjectives with those of the LLM, allowing us to draw direct conclusions regarding underlying mechanisms. As expected, rule-based and analogical models explain the predictions of GPT-J equally well for adjectives with regular nominalization patterns. However, for adjectives with variable nominalization patterns, the analogical model provides a much better match. Furthermore, GPT-J's behavior is sensitive to the individual word frequencies, even for regular forms, a behavior that is consistent with an analogical account of regular forms but not a rule-based one. These findings refute the hypothesis that GPT-J's linguistic generalization on adjective nominalization involves rules, suggesting similarity operations on stored exemplars as the underlying mechanism. Overall, our study suggests that analogical processes play a bigger role in the linguistic generalization of LLMs than previously thought.
- Published
- 2024
39. Learning to Write Rationally: How Information Is Distributed in Non-Native Speakers' Essays
- Author
-
Tang, Zixin and van Hell, Janet G.
- Subjects
Computer Science - Computation and Language - Abstract
People tend to distribute information evenly in language production for better and clearer communication. In this study, we compared essays written by second language learners with various native language (L1) backgrounds to investigate how they distribute information in their non-native language (L2) production. Analyses of surprisal and constancy of entropy rate indicated that writers with higher L2 proficiency can reduce the expected uncertainty of language production while still conveying informative content. However, the uniformity of information distribution showed less variability among different groups of L2 speakers, suggesting that this feature may be universal in L2 essay writing and less affected by L2 writers' variability in L1 background and L2 proficiency., Comment: To appear in main of Conference on Empirical Methods in Natural Language Processing; EMNLP 2024
- Published
- 2024
40. Zero-bias new particle searches using autoencoders in UPCs and diffractive events
- Author
-
Ragoni, Simone, Seger, Janet, and Anson, Christopher
- Subjects
High Energy Physics - Phenomenology ,High Energy Physics - Experiment - Abstract
We present an application of unsupervised learning for zero-bias detection of rare particle decays and exotic hadrons in low-background environments such as those characteristic of diffractive events and ultraperipheral pp, p--A, or A--A collisions at the CERN Large Hadron Collider (LHC), or in e--A collisions at the ePIC experiment at the future Electron-Ion Collider (EIC). Using a toy dataset simulating the decays of known resonances, including $\ensuremath{{\mathrm J}/\psi}\xspace$ and {\ensuremath{\psi'}\xspace}, as well as more exotic candidates, we implement an autoencoder neural network to identify anomalies in the decay kinematics. The autoencoder, trained solely on typical events, is designed to reconstruct normal decays with low error while flagging anomalous decays based on the reconstruction error. We demonstrate that the autoencoder successfully separates typical decays from rare exotic events, with peaks in the invariant mass distribution corresponding to the injected rare signals. Our method shows promise in detecting rare, unpredicted processes in large-scale collider data, offering an effective approach for discovering new physics beyond the Standard Model., Comment: 8 pages, 4 figures
- Published
- 2024
41. GDTB: Genre Diverse Data for English Shallow Discourse Parsing across Modalities, Text Types, and Domains
- Author
-
Liu, Yang Janet, Aoyama, Tatsuya, Scivetti, Wesley, Zhu, Yilun, Behzad, Shabnam, Levine, Lauren Elizabeth, Lin, Jessica, Tiwari, Devika, and Zeldes, Amir
- Subjects
Computer Science - Computation and Language - Abstract
Work on shallow discourse parsing in English has focused on the Wall Street Journal corpus, the only large-scale dataset for the language in the PDTB framework. However, the data is not openly available, is restricted to the news domain, and is by now 35 years old. In this paper, we present and evaluate a new open-access, multi-genre benchmark for PDTB-style shallow discourse parsing, based on the existing UD English GUM corpus, for which discourse relation annotations in other frameworks already exist. In a series of experiments on cross-domain relation classification, we show that while our dataset is compatible with PDTB, substantial out-of-domain degradation is observed, which can be alleviated by joint training on both datasets., Comment: Accepted to EMNLP 2024 (main, long); camera-ready version
- Published
- 2024
42. Pole and zero edge state invariant for 1D non-Hermitian sublattice symmetry
- Author
-
Zhong, Janet, Wang, Heming, and Fan, Shanhui
- Subjects
Condensed Matter - Mesoscale and Nanoscale Physics ,Quantum Physics - Abstract
There have been several criteria for the existence of topological edge states in 1D non-Hermitian two-band sublattice-symmetric tight-binding Hamiltonians. The generalized Brillouin zone (GBZ) approach uses the integration of the Berry connection over the GBZ contour in the complex wavevector space. An alternate `pole-zero' approach uses algebraic properties of the off-diagonal matrix elements of the sublattice-symmetric Hamiltonian in off-diagonal form. Both correctly predict the presence or absence of edge states, but there has not been an explicit proof of their equivalence. Here we provide such an explicit proof and moreover we extend the pole-zero approach so that it also applies for sublattice-symmetric models when the Hamiltonian is not in off-diagonal form. We give numerical examples for these invariants.
- Published
- 2024
43. One Language, Many Gaps: Evaluating Dialect Fairness and Robustness of Large Language Models in Reasoning Tasks
- Author
-
Lin, Fangru, Mao, Shaoguang, La Malfa, Emanuele, Hofmann, Valentin, de Wynter, Adrian, Wang, Xun, Chen, Si-Qing, Wooldridge, Michael, Pierrehumbert, Janet B., and Wei, Furu
- Subjects
Computer Science - Computation and Language ,Computer Science - Machine Learning - Abstract
Language is not monolithic. While benchmarks, including those designed for multiple languages, are often used as proxies to evaluate the performance of Large Language Models (LLMs), they tend to overlook the nuances of within-language variation, and thus fail to model the experience of speakers of non-standard dialects. Focusing on African American Vernacular English (AAVE), we present the first study aimed at objectively assessing the fairness and robustness of LLMs in handling dialects in canonical reasoning tasks, including algorithm, math, logic, and integrated reasoning. We introduce \textbf{ReDial} (\textbf{Re}asoning with \textbf{Dial}ect Queries), a benchmark containing 1.2K+ parallel query pairs in Standardized English and AAVE. We hire AAVE speakers, including experts with computer science backgrounds, to rewrite seven popular benchmarks, such as HumanEval and GSM8K. With ReDial, we evaluate widely used LLMs, including GPT, Claude, Llama, Mistral, and the Phi model families. Our findings reveal that \textbf{almost all of these widely used models show significant brittleness and unfairness to queries in AAVE}. Our work establishes a systematic and objective framework for analyzing LLM bias in dialectal queries. Moreover, it highlights how mainstream LLMs provide unfair service to dialect speakers in reasoning tasks, laying a critical foundation for relevant future research. Code and data can be accessed at https://github.com/fangru-lin/redial_dialect_robustness_fairness.
- Published
- 2024
44. Five-fold precision enhancement in a cold atom experiment via adaptive symmetry-informed Bayesian strategies
- Author
-
Overton, Matt, Rubio, Jesús, Cooper, Nathan, Baldolini, Daniele, Johnson, David, Anders, Janet, and Hackermüller, Lucia
- Subjects
Quantum Physics ,Physics - Atomic Physics ,Physics - Data Analysis, Statistics and Probability - Abstract
Bayesian methods promise enhanced device performance and accelerated data collection. We demonstrate an adaptive Bayesian measurement strategy for atom number estimation in a quantum technology experiment, utilising a symmetry-informed loss function. Compared to a standard unoptimised strategy, our method yields a five-fold reduction in the fractional variance of the atom number estimate. Equivalently, it achieves the target precision with a third of the data points previously required. We provide general expressions for the optimal estimator and error for any quantity amenable to symmetry-informed strategies, facilitating the application of these strategies in quantum computing, communication, metrology, and the wider quantum technology sector., Comment: 6 + 5 pages, 3 + 2 figures, 1 + 1 tables. Updated references and minor revisions
- Published
- 2024
45. Machine learning opportunities for online and offline tagging of photo-induced and diffractive events in continuous readout experiments
- Author
-
Ragoni, Simone, Seger, Janet, Anson, Christopher, and Tlusty, David
- Subjects
High Energy Physics - Experiment - Abstract
The increasing data rates in modern high-energy physics experiments such as ALICE at the LHC and the upcoming ePIC experiment at the Electron-Ion Collider (EIC) present significant challenges in real-time event selection and data storage. This paper explores the novel application of machine learning techniques, to enhance the identification of rare low-multiplicity events, such as ultraperipheral collisions (UPCs) and central exclusive diffractive processes. We focus on utilising machine learning models to perform early event classification, even before full event reconstruction, in continuous readout systems. We estimate data rates and disk space requirements for photoproduction and central exclusive diffractive processes in both ALICE and ePIC. We show that machine learning techniques can not only optimize data selection but also significantly reduce storage requirements in continuous readout environments, providing a scalable solution for the upcoming era of high-luminosity particle physics experiments., Comment: 12 pages, 6 figures
- Published
- 2024
46. Extra cost of erasure due to quantum lifetime broadening
- Author
-
Dunlop, Joe, Cerisola, Federico, Monsel, Juliette, Sevitz, Sofia, Tabanera-Bravo, Jorge, Dexter, Jonathan, Fedele, Federico, Ares, Natalia, and Anders, Janet
- Subjects
Quantum Physics - Abstract
The energy cost of erasing a bit of information was fundamentally lower bounded by Landauer, in terms of the temperature of its environment: $W\geq k_\mathrm{B} T \ln 2$. However, in real electronic devices, the information-bearing system is usually in contact with two or more electrodes, with different temperatures and chemical potentials. It is not clear what sets the cost of erasure in such nonequilibrium situations. One promising technology for testing the thermodynamic limits of information processing is quantum dots, in which a bit is encoded in the presence or absence of a single electron. We here develop a thermodynamic description of devices of this type and find that, in addition to the electrode temperatures, the potential difference across the quantum dot and lifetime broadening of its energy level contribute to the minimum work cost of erasure. In practical contexts, these contributions may significantly outweigh the cost due to temperature alone., Comment: 6 pages plus 8-page supplemental material. 3 figures
- Published
- 2024
47. Data-Centric AI Governance: Addressing the Limitations of Model-Focused Policies
- Author
-
Gupta, Ritwik, Walker, Leah, Corona, Rodolfo, Fu, Stephanie, Petryk, Suzanne, Napolitano, Janet, Darrell, Trevor, and Reddie, Andrew W.
- Subjects
Computer Science - Computers and Society ,Computer Science - Artificial Intelligence - Abstract
Current regulations on powerful AI capabilities are narrowly focused on "foundation" or "frontier" models. However, these terms are vague and inconsistently defined, leading to an unstable foundation for governance efforts. Critically, policy debates often fail to consider the data used with these models, despite the clear link between data and model performance. Even (relatively) "small" models that fall outside the typical definitions of foundation and frontier models can achieve equivalent outcomes when exposed to sufficiently specific datasets. In this work, we illustrate the importance of considering dataset size and content as essential factors in assessing the risks posed by models both today and in the future. More broadly, we emphasize the risk posed by over-regulating reactively and provide a path towards careful, quantitative evaluation of capabilities that can lead to a simplified regulatory environment.
- Published
- 2024
48. PepINVENT: Generative peptide design beyond the natural amino acids
- Author
-
Geylan, Gökçe, Janet, Jon Paul, Tibo, Alessandro, He, Jiazhen, Patronov, Atanas, Kabeshov, Mikhail, David, Florian, Czechtizky, Werngard, Engkvist, Ola, and De Maria, Leonardo
- Subjects
Quantitative Biology - Biomolecules ,Computer Science - Artificial Intelligence - Abstract
Peptides play a crucial role in the drug design and discovery whether as a therapeutic modality or a delivery agent. Non-natural amino acids (NNAAs) have been used to enhance the peptide properties from binding affinity, plasma stability to permeability. Incorporating novel NNAAs facilitates the design of more effective peptides with improved properties. The generative models used in the field, have focused on navigating the peptide sequence space. The sequence space is formed by combinations of a predefined set of amino acids. However, there is still a need for a tool to explore the peptide landscape beyond this enumerated space to unlock and effectively incorporate de novo design of new amino acids. To thoroughly explore the theoretical chemical space of the peptides, we present PepINVENT, a novel generative AI-based tool as an extension to the small molecule molecular design platform, REINVENT. PepINVENT navigates the vast space of natural and non-natural amino acids to propose valid, novel, and diverse peptide designs. The generative model can serve as a central tool for peptide-related tasks, as it was not trained on peptides with specific properties or topologies. The prior was trained to understand the granularity of peptides and to design amino acids for filling the masked positions within a peptide. PepINVENT coupled with reinforcement learning enables the goal-oriented design of peptides using its chemistry-informed generative capabilities. This study demonstrates PepINVENT's ability to explore the peptide space with unique and novel designs, and its capacity for property optimization in the context of therapeutically relevant peptides. Our tool can be employed for multi-parameter learning objectives, peptidomimetics, lead optimization, and variety of other tasks within the peptide domain.
- Published
- 2024
49. On the difference between thermalization in open and isolated quantum systems: a case study
- Author
-
Purkayastha, Archak, Guarnieri, Giacomo, Anders, Janet, and Merkli, Marco
- Subjects
Condensed Matter - Mesoscale and Nanoscale Physics ,Condensed Matter - Statistical Mechanics ,Quantum Physics - Abstract
Thermalization of isolated and open quantum systems has been studied extensively. However, being the subject of investigation by different scientific communities and being analysed using different mathematical tools, the connection between the isolated (IQS) and open (OQS) approaches to thermalization has remained opaque. Here we demonstrate that the fundamental difference between the two paradigms is the order in which the long time and the thermodynamic limits are taken. This difference implies that they describe physics on widely different time and length scales. Our analysis is carried out numerically for the case of a double quantum dot (DQD) coupled to a fermionic lead. We show how both OQS and IQS thermalization can be explored in this model on equal footing, allowing a fair comparison between the two. We find that while the quadratically coupled (free) DQD experiences no isolated thermalization, it of course does experience open thermalization. For the non-linearly interacting DQD coupled to fermionic lead, we show by characterizing its spectral form factor and level spacing distribution, that the system falls in the twilight zone between integrable and non-integrable regimes, which we call partially non-integrable. We further evidence that, despite being only partially non-integrable and thereby falling outside the remit of the standard eigenstate thermalization hypothesis, it nevertheless experiences IQS as well as OQS thermalization.
- Published
- 2024
50. Neutrino yield and neutron shielding calculations for a high-power target installed in an underground setting
- Author
-
Bungau, Adriana, Alonso, Jose, Barlow, Roger, Bartozsek, Larry, Conrad, Janet, Shaevitz, Michael, Spitz, Joshua, and Winklehner, Daniel
- Subjects
High Energy Physics - Experiment - Abstract
With the ever increasing beam power at particle accelerator-based facilities for nuclear and particle physics, radioactive isotope production, and nuclear engineering, targets that can withstand this power, and shielding of secondary particles are becoming increasingly important. Here we present Monte Carlo (MC) calculations using the well-established Geant4 software to optimise and predict the antineutrino yield of a $^8$Li Decay-At-Rest (DAR) source. The source relies on 600~kW of beam power from a continuous wave proton beam impinging on a beryllium target, where spallation neutrons capture on $^7$Li to produce the $^8$Li. We further present an in-depth treatment of the neutron shielding surrounding this target. We show that we can produce the high antineutrino flux needed for the discovery-level experiment IsoDAR, searching for ``sterile'' neutrinos (predicted new fundamental particles) and other beyond standard model physics, while maintaining a neutron flux in the detector that is below natural backgrounds. The methods presented in this paper are easily transferable to other high-power targets and their associated shielding.
- Published
- 2024
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.