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Affective polarization and increasing social divisions affect social mixing and the spread of information across online and physical spaces, reinforcing social and electoral cleavages and influencing political outcomes. Here, using aggregated and de-identified co-location and online network data, we investigate the relationship between partisan exposure and voting patterns in the USA by comparing three dimensions of partisan exposure: physical proximity and exposure to the same social contexts, online social ties, and residential sorting. By leveraging various statistical modeling approaches, we consistently find that partisan exposure in the physical space, as captured by co-location patterns, more accurately predicts electoral outcomes in US counties, outperforming online and residential exposures across metropolitan and non-metro areas. Moreover, our results show that physical partisan proximity is the best predictor of voting patterns in swing counties, where the election results are most uncertain. We also estimate county-level experienced partisan segregation and examine its relationship with individuals' demographic and socioeconomic characteristics. Focusing on metropolitan areas, our results confirm the presence of extensive partisan segregation in the US and show that offline partisan isolation, both considering physical encounters or residential sorting, is higher than online segregation and is primarily associated with educational attainment. Our findings emphasize the importance of physical space in understanding the relationship between social networks and political behavior, in contrast to the intense scrutiny focused on online social networks and elections., Comment: 13 pages, 4 figures, SI Appendix: 26 pages

Contact matrices have become a key ingredient of modern epidemic models. They account for the stratification of contacts for the age of individuals and, in some cases, the context of their interactions. However, age and context are not the only factors shaping contact structures and affecting the spreading of infectious diseases. Socio-economic status (SES) variables such as wealth, ethnicity, and education play a major role as well. Here, we introduce generalized contact matrices capable of stratifying contacts across any number of dimensions including any SES variable. We derive an analytical expression for the basic reproductive number of an infectious disease unfolding on a population characterized by such generalized contact matrices. Our results, on both synthetic and real data, show that disregarding higher levels of stratification might lead to the under-estimation of the reproductive number and to a mis-estimation of the global epidemic dynamics. Furthermore, including generalized contact matrices allows for more expressive epidemic models able to capture heterogeneities in behaviours such as different levels of adoption of non-pharmaceutical interventions across different groups. Overall, our work contributes to the literature attempting to bring socio-economic, as well as other dimensions, to the forefront of epidemic modeling. Tackling this issue is crucial for developing more precise descriptions of epidemics, and thus to design better strategies to contain them.

The course of an epidemic can be drastically altered by changes in human behavior. Incorporating the dynamics of individual decision-making during an outbreak represents a key challenge of epidemiology, faced by several modeling approaches siloed by different disciplines. Here, we propose an epi-economic model including adaptive, forward-looking behavioral response on a heterogeneous networked substrate, where individuals tune their social activity based on future health expectations. Under basic assumptions, we show that it is possible to derive an analytical expression of the optimal value of the social activity that matches the traditional assumptions of classic epidemic models. Through numerical simulations, we contrast the settings of global awareness -- individuals only know the prevalence of the disease in the population -- with local awareness, where individuals explicitly know which of their contacts are infected. We show that behavior change can flatten the epidemic curve by lowering the peak prevalence, but local awareness is much more effective in curbing the disease early with respect to global awareness. Our work bridges classical epidemic modeling with the epi-economic approach, and sheds light on the effects of heterogeneous behavioral responses in curbing the epidemic spread.

Mobile phone data have been widely used to model the spread of COVID-19, however, quantifying and comparing their predictive value across different settings is challenging. Their quality is affected by various factors and their relationship with epidemiological indicators varies over time. Here we adopt a model-free approach based on transfer entropy to quantify the relationship between mobile phone-derived mobility metrics and COVID-19 cases and deaths in more than 200 European subnational regions. We found that past knowledge of mobility does not provide statistically significant information on COVID-19 cases or deaths in most of the regions. In the remaining ones, measures of contact rates were often more informative than movements in predicting the spread of the disease, while the most predictive metrics between mid-range and short-range movements depended on the region considered. We finally identify geographic and demographic factors, such as users' coverage and commuting patterns, that can help determine the best metric for predicting disease incidence in a particular location. Our approach provides epidemiologists and public health officials with a general framework to evaluate the usefulness of human mobility data in responding to epidemics.

Urban agglomerations are constantly and rapidly evolving ecosystems, with globalization and increasing urbanization posing new challenges in sustainable urban development well summarized in the United Nations' Sustainable Development Goals (SDGs). The advent of the digital age generated by modern alternative data sources provides new tools to tackle these challenges with spatio-temporal scales that were previously unavailable with census statistics. In this review, we present how new digital data sources are employed to provide data-driven insights to study and track (i) urban crime and public safety; (ii) socioeconomic inequalities and segregation; and (iii) public health, with a particular focus on the city scale.

Contact matrices are a commonly adopted data representation, used to develop compartmental models for epidemic spreading, accounting for the contact heterogeneities across age groups. Their estimation, however, is generally time and effort consuming and model-driven strategies to quantify the contacts are often needed. In this article we focus on household contact matrices, describing the contacts among the members of a family and develop a parametric model to describe them. This model combines demographic and easily quantifiable survey-based data and is tested on high resolution proximity data collected in two sites in South Africa. Given its simplicity and interpretability, we expect our method to be easily applied to other contexts as well and we identify relevant questions that need to be addressed during the data collection procedure.

Developing safe infrastructure for micromobility like bicycles or e-scooters is an efficient pathway towards climate-friendly, sustainable, and livable cities. However, urban micromobility infrastructure is typically planned ad-hoc and at best informed by survey data. Here we study how data of micromobility trips and crashes can shape and automatize such network planning processes. We introduce a parameter that tunes the focus between demand-based and safety-based development, and investigate systematically this tradeoff for the city of Turin. We find that a full focus on demand or safety generates different network extensions in the short term, with an optimal tradeoff in-between. In the long term our framework improves overall network quality independent of short-term focus. Thus, we show how a data-driven process can provide urban planners with automated assistance for variable short-term scenario planning while maintaining the long-term goal of a sustainable, city-spanning micromobility network., Comment: Main text: 16 pages, 5 figures, SI: 12 pages, 9 figures, 4 tables

Ending poverty in all its forms everywhere is the number one Sustainable Development Goal of the UN 2030 Agenda. To monitor the progress towards such an ambitious target, reliable, up-to-date and fine-grained measurements of socioeconomic indicators are necessary. When it comes to socioeconomic development, novel digital traces can provide a complementary data source to overcome the limits of traditional data collection methods, which are often not regularly updated and lack adequate spatial resolution. In this study, we collect publicly available and anonymous advertising audience estimates from Facebook to predict socioeconomic conditions of urban residents, at a fine spatial granularity, in four large urban areas: Atlanta (USA), Bogot\'a (Colombia), Santiago (Chile), and Casablanca (Morocco). We find that behavioral attributes inferred from the Facebook marketing platform can accurately map the socioeconomic status of residential areas within cities, and that predictive performance is comparable in both high and low-resource settings. We also show that training a model on attributes of adult Facebook users, aged more than 25, leads to a more accurate mapping of socioeconomic conditions in all cities. Our work provides additional evidence of the value of social advertising media data to measure human development.

This paper describes how mobile phone data can guide government and public health authorities in determining the best course of action to control the COVID-19 pandemic and in assessing the effectiveness of control measures such as physical distancing. It identifies key gaps and reasons why this kind of data is only scarcely used, although their value in similar epidemics has proven in a number of use cases. It presents ways to overcome these gaps and key recommendations for urgent action, most notably the establishment of mixed expert groups on national and regional level, and the inclusion and support of governments and public authorities early on. It is authored by a group of experienced data scientists, epidemiologists, demographers and representatives of mobile network operators who jointly put their work at the service of the global effort to combat the COVID-19 pandemic.

In the global move toward urbanization, making sure the people remaining in rural areas are not left behind in terms of development and policy considerations is a priority for governments worldwide. However, it is increasingly challenging to track important statistics concerning this sparse, geographically dispersed population, resulting in a lack of reliable, up-to-date data. In this study, we examine the usefulness of the Facebook Advertising platform, which offers a digital "census" of over two billions of its users, in measuring potential rural-urban inequalities. We focus on Italy, a country where about 30% of the population lives in rural areas. First, we show that the population statistics that Facebook produces suffer from instability across time and incomplete coverage of sparsely populated municipalities. To overcome such limitation, we propose an alternative methodology for estimating Facebook Ads audiences that nearly triples the coverage of the rural municipalities from 19% to 55% and makes feasible fine-grained sub-population analysis. Using official national census data, we evaluate our approach and confirm known significant urban-rural divides in terms of educational attainment and income. Extending the analysis to Facebook-specific user "interests" and behaviors, we provide further insights on the divide, for instance, finding that rural areas show a higher interest in gambling. Notably, we find that the most predictive features of income in rural areas differ from those for urban centres, suggesting researchers need to consider a broader range of attributes when examining rural wellbeing. The findings of this study illustrate the necessity of improving existing tools and methodologies to include under-represented populations in digital demographic studies -- the failure to do so could result in misleading observations, conclusions, and most importantly, policies., Comment: To be published in the Proceedings of The Web Conference 2020 (WWW '20)

The use of public transportation or simply moving about in streets are gendered issues. Women and girls often engage in multi-purpose, multi-stop trips in order to do household chores, work, and study ('trip chaining'). Women-headed households are often more prominent in urban settings and they tend to work more in low-paid/informal jobs than men, with limited access to transportation subsidies. Here we present recent results on urban mobility from a gendered perspective by uniquely combining a wide range of datasets, including commercial sources of telecom and open data. We explored urban mobility of women and men in the greater metropolitan area of Santiago, Chile, by analyzing the mobility traces extracted from the Call Detail Records (CDRs) of a large cohort of anonymized mobile phone users over a period of 3 months. We find that, taking into account the differences in users' calling behaviors, women move less than men, visiting less unique locations and distributing their time less equally among such locations. By mapping gender differences in mobility over the 52 comunas of Santiago, we find a higher mobility gap to be correlated with socio-economic indicators, such as a lower average income, and with the lack of public and private transportation options. Such results provide new insights for policymakers to design more gender inclusive transportation plans in the city of Santiago., Comment: 32 pages, 4 figures

Over the past several decades, naturally occurring and man-made mass casualty incidents (MCI) have increased in frequency and number, worldwide. To test the impact of such event on medical resources, simulations can provide a safe, controlled setting while replicating the chaotic environment typical of an actual disaster. A standardised method to collect and analyse data from mass casualty exercises is needed, in order to assess preparedness and performance of the healthcare staff involved. We report on the use of wearable proximity sensors to measure proximity events during a MCI simulation. We investigated the interactions between medical staff and patients, to evaluate the time dedicated by the medical staff with respect to the severity of the injury of the victims depending on the roles. We estimated the presence of the patients in the different spaces of the field hospital, in order to study the patients' flow. Data were obtained and collected through the deployment of wearable proximity sensors during a mass casualty incident functional exercise. The scenario included two areas: the accident site and the Advanced Medical Post (AMP), and the exercise lasted 3 hours. A total of 238 participants simulating medical staff and victims were involved. Each participant wore a proximity sensor and 30 fixed devices were placed in the field hospital. The contact networks show a heterogeneous distribution of the cumulative time spent in proximity by participants. We obtained contact matrices based on cumulative time spent in proximity between victims and the rescuers. Our results showed that the time spent in proximity by the healthcare teams with the victims is related to the severity of the patient's injury. The analysis of patients' flow showed that the presence of patients in the rooms of the hospital is consistent with triage code and diagnosis, and no obvious bottlenecks were found.

We present new empirical evidence, based on millions of interactions on Twitter, confirming that human contacts scale with population sizes. We integrate such observations into a reaction-diffusion metapopulation framework providing an analytical expression for the global invasion threshold of a contagion process. Remarkably, the scaling of human contacts is found to facilitate the spreading dynamics. Our results show that the scaling properties of human interactions can significantly affect dynamical processes mediated by human contacts such as the spread of diseases, and ideas.

Human mobility is a key component of large-scale spatial-transmission models of infectious diseases. Correctly modeling and quantifying human mobility is critical for improving epidemic control policies, but may be hindered by incomplete data in some regions of the world. Here we explore the opportunity of using proxy data or models for individual mobility to describe commuting movements and predict the diffusion of infectious disease. We consider three European countries and the corresponding commuting networks at different resolution scales obtained from official census surveys, from proxy data for human mobility extracted from mobile phone call records, and from the radiation model calibrated with census data. Metapopulation models defined on the three countries and integrating the different mobility layers are compared in terms of epidemic observables. We show that commuting networks from mobile phone data well capture the empirical commuting patterns, accounting for more than 87% of the total fluxes. The distributions of commuting fluxes per link from both sources of data - mobile phones and census - are similar and highly correlated, however a systematic overestimation of commuting traffic in the mobile phone data is observed. This leads to epidemics that spread faster than on census commuting networks, however preserving the order of infection of newly infected locations. Match in the epidemic invasion pattern is sensitive to initial conditions: the radiation model shows higher accuracy with respect to mobile phone data when the seed is central in the network, while the mobile phone proxy performs better for epidemics seeded in peripheral locations. Results suggest that different proxies can be used to approximate commuting patterns across different resolution scales in spatial epidemic simulations, in light of the desired accuracy in the epidemic outcome under study., Comment: Accepted fro publication in PLOS Computational Biology. Abstract shortened to fit Arxiv limits. 35 pages, 6 figures

Host mobility plays a fundamental role in the spatial spread of infectious diseases. Previous theoretical works based on the integration of network theory into the metapopulation framework have shown that the heterogeneities that characterize real mobility networks favor the propagation of epidemics. Nevertheless, the studies conducted so far assumed the mobility process to be either Markovian or non-Markovian with a fixed traveling time scale. Available statistics however show that the time spent by travelers at destination is characterized by wide fluctuations, ranging between a single day up to several months. Such varying length of stay crucially affects the chance and duration of mixing events among hosts and may therefore have a strong impact on the spread of an emerging disease. Here, we present an analytical and computational study of epidemic processes on a complex subpopulation network where travelers have memory of their origin and spend a heterogeneously distributed time interval at their destination. Through analytical calculations and numerical simulations we show that the heterogeneity of the length of stay alters the expression of the threshold between local outbreak and global invasion, and, moreover, it changes the epidemic behavior of the system in case of a global outbreak. Additionally, our theoretical framework allows us to study the effect of changes in the traveling behavior in response to the infection, by considering a scenario in which sick individuals do not leave their home location. Finally, we compare the results of our non-Markovian framework with those obtained with a classic Markovian approach and find relevant differences between the two, in the estimate of the epidemic invasion potential, as well as of the timing and the pattern of its spatial spread., Comment: 51 pages, 13 figures; due to the limitation of 1,920 characters, the abstract appearing here is slightly shorter than that in the PDF file

Infectious diseases outbreaks are often characterized by a spatial component induced by hosts' distribution, mobility, and interactions. Spatial models that incorporate hosts' movements are being used to describe these processes, to investigate the conditions for propagation, and to predict the spatial spread. Several assumptions are being considered to model hosts' movements, ranging from permanent movements to daily commuting, where the time spent at destination is either infinite or assumes a homogeneous fixed value, respectively. Prompted by empirical evidence, here we introduce a general metapopulation approach to model the disease dynamics in a spatially structured population where the mobility process is characterized by a heterogeneous length of stay. We show that large fluctuations of the length of stay, as observed in reality, can have a significant impact on the threshold conditions for the global epidemic invasion, thus altering model predictions based on simple assumptions, and displaying important public health implications., Comment: 31 pages, 7 figures

The unfolding of pandemic influenza A(H1N1) for Fall 2009 in the Northern Hemisphere is still uncertain. Plans for vaccination campaigns and vaccine trials are underway, with the first batches expected to be available early October. Several studies point to the possibility of an anticipated pandemic peak that could undermine the effectiveness of vaccination strategies. Here we use a structured global epidemic and mobility metapopulation model to assess the effectiveness of massive vaccination campaigns for the Fall/Winter 2009. Mitigation effects are explored depending on the interplay between the predicted pandemic evolution and the expected delivery of vaccines. The model is calibrated using recent estimates on the transmissibility of the new A(H1N1) influenza. Results show that if additional intervention strategies were not used to delay the time of pandemic peak, vaccination may not be able to considerably reduce the cumulative number of cases, even when the mass vaccination campaign is started as early as mid-October. Prioritized vaccination would be crucial in slowing down the pandemic evolution and reducing its burden., Comment: Paper: 19 Pages, 3 Figures. Supplementary Information: 10 pages, 8 Tables

On 11 June the World Health Organization officially raised the phase of pandemic alert (with regard to the new H1N1 influenza strain) to level 6. We use a global structured metapopulation model integrating mobility and transportation data worldwide in order to estimate the transmission potential and the relevant model parameters we used the data on the chronology of the 2009 novel influenza A(H1N1). The method is based on the maximum likelihood analysis of the arrival time distribution generated by the model in 12 countries seeded by Mexico by using 1M computationally simulated epidemics. An extended chronology including 93 countries worldwide seeded before 18 June was used to ascertain the seasonality effects. We found the best estimate R0 = 1.75 (95% CI 1.64 to 1.88) for the basic reproductive number. Correlation analysis allows the selection of the most probable seasonal behavior based on the observed pattern, leading to the identification of plausible scenarios for the future unfolding of the pandemic and the estimate of pandemic activity peaks in the different hemispheres. We provide estimates for the number of hospitalizations and the attack rate for the next wave as well as an extensive sensitivity analysis on the disease parameter values. We also studied the effect of systematic therapeutic use of antiviral drugs on the epidemic timeline. The analysis shows the potential for an early epidemic peak occurring in October/November in the Northern hemisphere, likely before large-scale vaccination campaigns could be carried out. We suggest that the planning of additional mitigation policies such as systematic antiviral treatments might be the key to delay the activity peak inorder to restore the effectiveness of the vaccination programs., Comment: Paper: 29 Pages, 3 Figures and 5 Tables. Supplementary Information: 29 Pages, 5 Figures and 7 Tables. Print version: http://www.biomedcentral.com/1741-7015/7/45