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1. Commentaries: Name Changes in Medically Important Fungi and Their Implications for Clinical Practice

Author

de Hoog, G Sybren, Chaturvedi, Vishnu, Denning, David W, Dyer, Paul S, Frisvad, Jens Christian, Geiser, David, Gräser, Yvonne, Guarro, Josep, Haase, Gerhard, Kwon-Chung, Kyung-Joo, Meis, Jacques F, Meyer, Wieland, Pitt, John I, Samson, Robert A, Taylor, John W, Tintelnot, Kathrin, Vitale, Roxana G, Walsh, Thomas J, and Lackner, Michaela

Subjects
Fungi, Humans, Infectious Disease Medicine, Mycology, Mycoses, Terminology as Topic, ISHAM Working Group on Nomenclature of Medical Fungi, Biological Sciences, Agricultural and Veterinary Sciences, Medical and Health Sciences, Microbiology
Abstract

Recent changes in the Fungal Code of Nomenclature and developments in molecular phylogeny are about to lead to dramatic changes in the naming of medically important molds and yeasts. In this article, we present a widely supported and simple proposal to prevent unnecessary nomenclatural instability.

Published
2015

3. Correction to: Proposed nomenclature for Pseudallescheria, Scedosporium and related genera

Author

Lackner, Michaela, de Hoog, G. Sybren, Yang, Liyue, Ferreira Moreno, Leandro, Ahmed, Sarah A., Andreas, Fritz, Kaltseis, Josef, Nagl, Markus, Lass-Flörl, Cornelia, Risslegger, Brigitte, Rambach, Günter, Speth, Cornelia, Robert, Vincent, Buzina, Walter, Chen, Sharon, Bouchara, Jean-Philippe, Cano-Lira, José F., Guarro, Josep, Gené, Josepa, Fernández Silva, Fabiola, Haido, Rosa, Haase, Gerhard, Havlicek, Vladimir, Garcia-Hermoso, Dea, Meis, Jacques F., Hagen, Ferry, Kirchmair, Martin, Rainer, Johannes, Schwabenbauer, Katharina, Zoderer, Mirjam, Meyer, Wieland, Gilgado, Felix, Schwabenbauer, Katharina, Vicente, Vania A., Piecková, Elena, Regenermel, Monika, Rath, Peter-Michael, Steinmann, Joerg, de Alencar, Xisto Wellington, Symoens, Françoise, Tintelnot, Kathrin, Ulfig, Krzysztof, Velegraki, Aristea, Tortorano, Anna Maria, Giraud, Sandrine, Mina, Sara, Rigler-Hohenwarter, Kinga, Hernando, Fernando L., Ramirez-Garcia, Andoni, Pellon, Aize, Kaur, Jashanpreet, Bergter, Eliana Barreto, de Meirelles, Jardel Vieira, da Silva, Ingrid Dutra, Delhaes, Laurence, Alastruey-Izquierdo, Ana, Li, Ruo-yu, Lu, Qiaoyun, Moussa, Tarek, Almaghrabi, Omar, Al-Zahrani, Hassan, Okada, Gen, Deng, Shuwen, Liao, Wangqing, Zeng, Jingsi, Issakainen, Jouni, and Liporagi Lopes, Livia Cristina

Published
2022
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10. Environmental distribution of Cryptococcus neoformans and C. gattii around the Mediterranean basin

Author

Cogliati, Massimo, DʼAmicis, Roberta, Zani, Alberto, Montagna, Maria Teresa, Caggiano, Giuseppina, De Giglio, Osvalda, Balbino, Stella, De Donno, Antonella, Serio, Francesca, Susever, Serdar, Ergin, Cagri, Velegraki, Aristea, Ellabib, Mohamed S., Nardoni, Simona, Macci, Cristina, Oliveri, Salvatore, Trovato, Laura, Dipineto, Ludovico, Rickerts, Volker, McCormick-Smith, Ilka, Akcaglar, Sevim, Tore, Okan, Mlinaric-Missoni, Emilija, Bertout, Sebastien, Mallié, Michele, Martins, Maria da Luz, Vencà, Ana C.F., Vieira, Maria L., Sampaio, Ana C., Pereira, Cheila, Griseo, Giuseppe, Romeo, Orazio, Ranque, Stéphane, Al-Yasiri, Mohammed H. Y., Kaya, Meltem, Cerikcioglu, Nilgun, Marchese, Anna, Vezzulli, Luigi, Ilkit, Macit, Desnos-Ollivier, Marie, Pasquale, Vincenzo, Korem, Maya, Polacheck, Itzhack, Scopa, Antonio, Meyer, Wieland, Ferreira-Paim, Kennio, Hagen, Ferry, Theelen, Bart, Boekhout, Teun, Lockhart, Shawn R., Tintelnot, Kathrin, Tortorano, Anna Maria, Dromer, Françoise, Varma, Ashok, Kwon-Chung, Kyung J., Inácio, Joäo, Alonso, Beatriz, and Colom, Maria F.

Published
2016
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11. (2952) Proposal to conserve the name Coccidioides posadasii against Posadasia esferiformis, Coccidium posadasi, Pseudococcidioides mazzae, Geotrichum louisianoideum, Glenospora meteuropea, Glenospora metamericana and Trichosporon proteolyticum...

Author

de Hoog, Sybren, Tintelnot, Kathrin, Fisher, Matthew C., Taylor, John W., and Redhead, Scott A.

Subjects
TRICHOSPORON
Abstract

Ophüls (l.c.) considered that I C. immitis i Rixford & Gilchrist and I C. pyogenes i Rixford & Gilchrist represented a single species that should be included in I Oidium i and stated "[...] Its name then would be I Oidium coccidioides i , or, if there should be objections to the adoption of coccidioides, I Oidium protozoides i ." There was always a greater likelihood that I C. pyogenes i was I C. immitis i than I C. posadasii i because of the prevalence of I C. immitis i in California. A second species, I C. pyogenes i , was simultaneously described with I C. immitis i in 1896 and could have been either I C. immitis i itself or I C. posadasii i . Additionally, B we hereby designate CBS No. H-19784 as epitype to the lectotype b (MBT 10011884), thus maintaining Tintelnot & al.'s (l.c.) application of the name, I C. immitis i , as a species distinct from I C. posadasii i . [Extracted from the article]

Published
2023
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12. Proposed nomenclature for Pseudallescheria, Scedosporium and related genera (vol 67, pg 1, 2014)

Author

Lackner, Michaela, de Hoog, G. Sybren, Yang, Liyue, Ferreira Moreno, Leandro, Ahmed, Sarah A., Andreas, Fritz, Kaltseis, Josef, Nagl, Markus, Lass-Floerl, Cornelia, Risslegger, Brigitte, Rambach, Guenter, Speth, Cornelia, Robert, Vincent, Buzina, Walter, Chen, Sharon, Bouchara, Jean-Philippe, Cano-Lira, Jose F., Guarro, Josep, Gene, Josepa, Fernandez Silva, Fabiola, Haido, Rosa, Haase, Gerhard, Havlicek, Vladimir, Garcia-Hermoso, Dea, Meis, Jacques F., Hagen, Ferry, Kirchmair, Martin, Rainer, Johannes, Schwabenbauer, Katharina, Zoderer, Mirjam, Meyer, Wieland, Gilgado, Felix, Vicente, Vania A., Pieckova, Elena, Regenermel, Monika, Rath, Peter-Michael, Steinmann, Joerg, de Alencar, Xisto Wellington, Symoens, Francoise, Tintelnot, Kathrin, Ulfig, Krzysztof, Velegraki, Aristea, Tortorano, Anna Maria, Giraud, Sandrine, Mina, Sara, Rigler-Hohenwarter, Kinga, Hernando, Fernando L., Ramirez-Garcia, Andoni, Pellon, Aize, Kaur, Jashanpreet, Bergter, Eliana Barreto, de Meirelles, Jardel Vieira, da Silva, Ingrid Dutra, Delhaes, Laurence, Alastruey-Izquierdo, Ana, Li, Ruo-yu, Lu, Qiaoyun, Moussa, Tarek, Almaghrabi, Omar, Al-Zahrani, Hassan, Okada, Gen, Deng, Shuwen, Liao, Wangqing, Zeng, Jingsi, Issakainen, Jouni, Liporagi Lopes, Livia Cristina, Westerdijk Fungal Biodiversity Institute, Westerdijk Fungal Biodiversity Institute - Software and Databasing, and Westerdijk Fungal Biodiversity Institute - Medical Mycology

Published
2022

15. Proposed nomenclature for Pseudallescheria, Scedosporium and related genera

Author

Lackner, Michaela, de Hoog, G. Sybren, Yang, Liyue, Ferreira Moreno, Leandro, Ahmed, Sarah A., Andreas, Fritz, Kaltseis, Josef, Nagl, Markus, Lass-Flörl, Cornelia, Risslegger, Brigitte, Rambach, Günter, Speth, Cornelia, Robert, Vincent, Buzina, Walter, Chen, Sharon, Bouchara, Jean-Philippe, Cano-Lira, José F., Guarro, Josep, Gené, Josepa, Fernández Silva, Fabiola, Haido, Rosa, Haase, Gerhard, Havlicek, Vladimir, Garcia-Hermoso, Dea, Meis, Jacques F., Hagen, Ferry, Kirchmair, Martin, Rainer, Johannes, Schwabenbauer, Katharina, Zoderer, Mirjam, Meyer, Wieland, Gilgado, Felix, Schwabenbauer, Katharina, Vicente, Vania A., Piecková, Elena, Regenermel, Monika, Rath, Peter-Michael, Steinmann, Joerg, de Alencar, Xisto Wellington, Symoens, Françoise, Tintelnot, Kathrin, Ulfig, Krzysztof, Velegraki, Aristea, Tortorano, Anna Maria, Giraud, Sandrine, Mina, Sara, Rigler-Hohenwarter, Kinga, Hernando, Fernando L., Ramirez-Garcia, Andoni, Pellon, Aize, Kaur, Jashanpreet, Bergter, Eliana Barreto, de Meirelles, Jardel Vieira, da Silva, Ingrid Dutra, Delhaes, Laurence, Alastruey-Izquerdo, Ana, Li, Ruo-yu, Lu, Qiaoyun, Moussa, Tarek, Almaghrabi, Omar, Al-Zahrani, Hassan, Okada, Gen, Deng, Shuwen, Liao, Wangqing, Zeng, Jingsi, Issakainen, Jouni, and Liporagi Lopes, Livia Cristina

Published
2014
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16. Multilocus Sequence Typing Reveals Extensive Genetic Diversity of the Emerging Fungal Pathogen Scedosporium aurantiacum

Author

Harun, Azian, primary, Kan, Alex, additional, Schwabenbauer, Katharina, additional, Gilgado, Felix, additional, Perdomo, Haybrig, additional, Firacative, Carolina, additional, Losert, Heidemarie, additional, Abdullah, Sarimah, additional, Giraud, Sandrine, additional, Kaltseis, Josef, additional, Fraser, Mark, additional, Buzina, Walter, additional, Lackner, Michaela, additional, Blyth, Christopher C., additional, Arthur, Ian, additional, Rainer, Johannes, additional, Lira, José F. Cano, additional, Artigas, Josep Guarro, additional, Tintelnot, Kathrin, additional, Slavin, Monica A., additional, Heath, Christopher H., additional, Bouchara, Jean-Philippe, additional, Chen, Sharon C. A., additional, and Meyer, Wieland, additional

Published
2021
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18. Autochthonous and dormant Cryptococcus gattii infections in Europe

Author

Hagen, Ferry, Colom, M. Francisca, Swinne, Danielle, Tintelnot, Kathrin, Iatta, Roberta, Montagna, Maria Teresa, Torres-Rodriguez, Josep M., Cogliati, Massimo, Velegraki, Aristea, Burggraaf, Arjan, Kamermans, Alwin, Sweere, Johanna M., Meis, Jacques F., Klaassen, Corne H.W., and Boekhout, Teun

Subjects
Research, Genetic aspects, Risk factors, Health aspects, Cryptococcus -- Health aspects -- Genetic aspects -- Research, Cryptococcosis -- Research -- Risk factors, Epidemiology -- Research, Cryptococcal infections -- Research -- Risk factors
Abstract

Until recently, Cryptococcus gattii infections occurred mainly in tropical and subtropical climate zones. However, during the past decade, C. gattii infections in humans and animals in Europe have increased. To [...]

Published
2012
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21. Comparison of histopathological analysis, culture, and polymerase chain reaction assays to detect invasive mold infections from biopsy specimens

Author

Rickerts, Volker, Mousset, Sabine, Lambrecht, Evelyn, Tintelnot, Kathrin, Schwerdtfeger, Rainer, Presterl, Elisabeth, Jacobi, Volkmar, Just-Nubling, Gudrun, and Bialek, Ralf

Subjects
Mycoses -- Diagnosis, Molds (Fungi) -- Identification and classification, Polymerase chain reaction -- Analysis, Tissue culture -- Analysis, Microbiological assay -- Analysis, Health, Health care industry
Published
2007

28. Disseminated Mycosis by Arthrocladium fulminans Jeopardizing a Patient with GATA2 Deficiency

Author

Egenlauf, Benjamin, Schuhmann, Maren, Giese, Thomas, Junghanss, Thomas, Stojkovic, Marija, Tintelnot, Kathrin, de Hoog, Sybren, Greil, Johann, Richter, Elvira, Vehresschild, Maria, Heussel, Claus Peter, Herth, Felix J F, Kreuter, Michael, Westerdijk Fungal Biodiversity Institute, and Westerdijk Fungal Biodiversity Institute - Medical Mycology

Abstract

GATA2 deficiency is characterized by monocytopenia, deficiency of dendritic cells, and a variable degree of lymphocytopenia affecting B cells and NK cells, leading to an enhanced risk of mycobacterial, viral, and fungal infections. Here we present a patient with a heterozygous intronic GATA2 mutation who acquired a fatal disseminated mycosis due to the black yeast-like fungus Arthrocladium fulminans following an infection with Mycobacterium sherrisii. This case illustrates that in patients with severe uncommon infections, immunodeficiency syndromes must be ruled out.

Published
2019

29. Antifungal Agents

Author

Müller, Johannes, primary, Polak, Annemarie, additional, Kappe, Reinhard, additional, Rimek, Dagmar, additional, Seibold, Michael, additional, and Tintelnot, Kathrin, additional

Published
2003
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41. Scedosporium and Lomentospora: an updated overview of underrated opportunists

Author

Ramirez-Garcia, Andoni, primary, Pellon, Aize, additional, Rementeria, Aitor, additional, Buldain, Idoia, additional, Barreto-Bergter, Eliana, additional, Rollin-Pinheiro, Rodrigo, additional, de Meirelles, Jardel Vieira, additional, Xisto, Mariana Ingrid D S, additional, Ranque, Stephane, additional, Havlicek, Vladimir, additional, Vandeputte, Patrick, additional, Govic, Yohann Le, additional, Bouchara, Jean-Philippe, additional, Giraud, Sandrine, additional, Chen, Sharon, additional, Rainer, Johannes, additional, Alastruey-Izquierdo, Ana, additional, Martin-Gomez, Maria Teresa, additional, López-Soria, Leyre M, additional, Peman, Javier, additional, Schwarz, Carsten, additional, Bernhardt, Anne, additional, Tintelnot, Kathrin, additional, Capilla, Javier, additional, Martin-Vicente, Adela, additional, Cano-Lira, Jose, additional, Nagl, Markus, additional, Lackner, Michaela, additional, Irinyi, Laszlo, additional, Meyer, Wieland, additional, de Hoog, Sybren, additional, and Hernando, Fernando L, additional

Published
2018
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42. Scedosporium and Lomentospora: An updated overview of underrated opportunists

Author

Ramirez-Garcia, Andoni, Pellon, Aize, Rementeria, Aitor, Buldain, Idoia, Barreto-Bergter, Eliana, Rollin-Pinheiro, Rodrigo, De Meirelles, Jardel Vieira, Xisto, Mariana Ingrid D.S., Ranque, Stephane, Havlicek, Vladimir, Vandeputte, Patrick, Govic, Yohann Le, Bouchara, Jean Philippe, Giraud, Sandrine, Chen, Sharon, Rainer, Johannes, Alastruey-Izquierdo, Ana, Martin-Gomez, Maria Teresa, López-Soria, Leyre M., Peman, Javier, Schwarz, Carsten, Bernhardt, Anne, Tintelnot, Kathrin, Capilla, Javier, Martin-Vicente, Adela, Cano-Lira, Jose, Nagl, Markus, Lackner, Michaela, Irinyi, Laszlo, Meyer, Wieland, De Hoog, Sybren, Hernando, Fernando L., Ramirez-Garcia, Andoni, Pellon, Aize, Rementeria, Aitor, Buldain, Idoia, Barreto-Bergter, Eliana, Rollin-Pinheiro, Rodrigo, De Meirelles, Jardel Vieira, Xisto, Mariana Ingrid D.S., Ranque, Stephane, Havlicek, Vladimir, Vandeputte, Patrick, Govic, Yohann Le, Bouchara, Jean Philippe, Giraud, Sandrine, Chen, Sharon, Rainer, Johannes, Alastruey-Izquierdo, Ana, Martin-Gomez, Maria Teresa, López-Soria, Leyre M., Peman, Javier, Schwarz, Carsten, Bernhardt, Anne, Tintelnot, Kathrin, Capilla, Javier, Martin-Vicente, Adela, Cano-Lira, Jose, Nagl, Markus, Lackner, Michaela, Irinyi, Laszlo, Meyer, Wieland, De Hoog, Sybren, and Hernando, Fernando L.

Abstract

Species of Scedosporium and Lomentospora are considered as emerging opportunists, affecting immunosuppressed and otherwise debilitated patients, although classically they are known from causing trauma-associated infections in healthy individuals. Clinical manifestations range from local infection to pulmonary colonization and severe invasive disease, in which mortality rates may be over 80%. These unacceptably high rates are due to the clinical status of patients, diagnostic difficulties, and to intrinsic antifungal resistance of these fungi. In consequence, several consortia have been founded to increase research efforts on these orphan fungi. The current review presents recent findings and summarizes the most relevant points, including the Scedosporium/Lomentospora taxonomy, environmental distribution, epidemiology, pathology, virulence factors, immunology, diagnostic methods, and therapeutic strategies.

Published
2018

43. Scedosporium and Lomentospora: an updated overview of underrated opportunists

Author

Inmunología, microbiología y parasitología, Immunologia, mikrobiologia eta parasitologia, Ramírez García, Andoni, Pellón Rodríguez, Aize, Rementeria Ruiz, Aitor Domingo, Buldain Garriz, Idoia, Barreto-Bergter, Eliana, Rollin-Pinheiro, Rodrigo, Vieira de Meirelles, Jardel, Xisto, Mariana Ingrid D. S., Ranque, Stephane, Havlicek, Vladimir, Vandeputte, Patrick, Le Govic, Yohann, Bouchara, Jean Philippe, Giraud, Sandrine, Chen, Sharon, Rainer, Johannes, Alastruey-Izquierdo, Ana, Martín Gómez, María Teresa, López Soria, Leyre, Pemán, Javier, Schwarz, Carsten, Bernhardt, Anne, Tintelnot, Kathrin, Capilla, Javier, Martin-Vicente, Adela, Cano-Lira, Jose, Nagl, Markus, Lackner, Michaela, Irinyi, Laszlo, Meyer, Wieland, de Hoog, Sybren, Hernando, Fernando Luis, Inmunología, microbiología y parasitología, Immunologia, mikrobiologia eta parasitologia, Ramírez García, Andoni, Pellón Rodríguez, Aize, Rementeria Ruiz, Aitor Domingo, Buldain Garriz, Idoia, Barreto-Bergter, Eliana, Rollin-Pinheiro, Rodrigo, Vieira de Meirelles, Jardel, Xisto, Mariana Ingrid D. S., Ranque, Stephane, Havlicek, Vladimir, Vandeputte, Patrick, Le Govic, Yohann, Bouchara, Jean Philippe, Giraud, Sandrine, Chen, Sharon, Rainer, Johannes, Alastruey-Izquierdo, Ana, Martín Gómez, María Teresa, López Soria, Leyre, Pemán, Javier, Schwarz, Carsten, Bernhardt, Anne, Tintelnot, Kathrin, Capilla, Javier, Martin-Vicente, Adela, Cano-Lira, Jose, Nagl, Markus, Lackner, Michaela, Irinyi, Laszlo, Meyer, Wieland, de Hoog, Sybren, and Hernando, Fernando Luis

Abstract

Species of Scedosporium and Lomentospora are considered as emerging opportunists, affecting immunosuppressed and otherwise debilitated patients, although classically they are known from causing trauma-associated infections in healthy individuals. Clinical manifestations range from local infection to pulmonary colonization and severe invasive disease, in which mortality rates may be over 80%. These unacceptably high rates are due to the clinical status of patients, diagnostic difficulties, and to intrinsic antifungal resistance of these fungi. In consequence, several consortia have been founded to increase research efforts on these orphan fungi. The current review presents recent findings and summarizes the most relevant points, including the Scedosporium/Lomentospora taxonomy, environmental distribution, epidemiology, pathology, virulence factors, immunology, diagnostic methods, and therapeutic strategies.

Published
2018

44. Environmental distribution of Cryptococcus neoformans and C. gattii around the Mediterranean basin (vol 16, 2016 )

Author

Desnos-Ollivier, Marie, Pasquale, Vincenzo, Korem, Maya, Polacheck, Itzhack, Scopa, Antonio, Meyer, Wieland, Ferreira-Paim, Kennio, Hagen, Ferry, Theelen, Bart, Boekhout, Teun, Lockhart, Shawn R., Tintelnot, Kathrin, Tortorano, Anna Maria, Varma, Ashok, Kwon-Chung, Kyung J., Inacio, Joao, Alonso, Beatriz, Colom, Maria F., Cogliati, Massimo, D'Amicis, Roberta, Zani, Alberto, Montagna, Maria Teresa, Caggiano, Giuseppina, De Giglio, Osvalda, Balbino, Stella, De Donno, Antonella, Serio, Francesca, Susever, Serdar, Ergin, Cagri, Velegraki, Aristea, Ellabib, Mohamed S., Nardoni, Simona, Macci, Cristina, Oliveri, Salvatore, Trovato, Laura, Dipineto, Ludovico, Rickerts, Volker, McCormick-Smith, Ilka, Akcaglar, Sevim, Tore, Okan, Mlinaric-Missoni, Emilija, Bertout, Sebastien, Mallie, Michele, Martins, Maria da Luz, Venca, Ana C. F., Vieira, Maria L., Sampaio, Ana C., Pereira, Cheila, Criseo, Giuseppe, Romeo, Orazio, Ranque, Stephane, Al-Yasiri, Mohammed H. Y., Kaya, Meltem, Cerikcioglu, Nilgun, Marchese, Anna, Vezzulli, Luigi, Ilkit, Macit, Centraalbureau voor Schimmelcultures (CBS), CBS-Centraalbureau voor Schimmelcultures, CBS-KNAW Fungal Biodiversity Centre, Applied Mathematics in Natural Resources, E.T.S. Ingenieros de Minas, Universidad Politécnica de Madrid, Department of Animal Pathology, Prophylaxis and Food Hygiene, University of Pisa - Università di Pisa, Department of Pathology and Animal Health, University of Naples Federico II = Università degli studi di Napoli Federico II, Medical Clinic III, Goethe-Universität Frankfurt am Main, Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR48, Institut des sciences biologiques (INSB-CNRS)-Institut des sciences biologiques (INSB-CNRS)-Centre National de la Recherche Scientifique (CNRS), Sezione di Microbiologia del DISCMIT, Università degli studi di Genova = University of Genoa (UniGe), Department of Earth, Environmental and Life Sciences (DISTAV), Università degli studi di Napoli Federico II, INSB-INSB-Centre National de la Recherche Scientifique (CNRS), University of Genoa (UNIGE), and Universita degli studi di Genova

Subjects
[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, ComputingMilieux_MISCELLANEOUS
Abstract

International audience; no abstract

Published
2016
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46. Disseminated Mycosis by Arthrocladiumfulminans Jeopardizing a Patient with GATA2 Deficiency.

Author

Egenlauf, Benjamin, Schuhmann, Maren, Giese, Thomas, Junghanss, Thomas, Stojkovic, Marija, Tintelnot, Kathrin, de Hoog, Sybren, Greil, Johann, Richter, Elvira, Vehresschild, Maria, Heussel, Claus Peter, Herth, Felix J.F., and Kreuter, Michael

Subjects
MYCOSES, GENETIC disorders, GENETIC mutation, SEVERITY of illness index, DISEASE complications, DISEASE risk factors
Abstract

GATA2 deficiency is characterized by monocytopenia, deficiency of dendritic cells, and a variable degree of lymphocytopenia affecting B cells and NK cells, leading to an enhanced risk of mycobacterial, viral, and fungal infections. Here we present a patient with a heterozygous intronic GATA2 mutation who acquired a fatal disseminated mycosis due to the black yeast-like fungus Arthrocladium fulminans following an infection with Mycobacterium sherrisii. This case illustrates that in patients with severe uncommon infections, immunodeficiency syndromes must be ruled out. [ABSTRACT FROM AUTHOR]

Published
2019
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47. Disseminated Neocosmospora vasinfecta Infection in a Patient with Acute Nonlymphocytic Leukemia

Author

Cornely, Oliver A., Chemnitz, Jens, Brochhagen, Hans-Georg, Lemmer, Karin, Schutt, Heidi, Sohngen, Dietmar, Staib, Peter, Wickenhauser, Claudia, Diehl, Volker, and Tintelnot, Kathrin

Subjects
Case studies, Pathogenic fungi -- Case studies, Myeloid leukemia -- Case studies, Fungi, Pathogenic -- Case studies, Myelocytic leukemia -- Case studies, Nonlymphoid leukemia -- Case studies
Abstract

We report Neocosmospora vasinfecta infection following chemotherapy for acute nonlymphocytic leukemia. N. vasinfecta, a plant pathogen, was identified by culture and genetic sequencing. Susceptibility testing revealed in vitro resistance for [...]

Published
2001

48. Cryptococcal Meningoencephalitis Relapse after an 8 Year Delay: An Interplay of Infection and Immune Reconstitution?

Author

Katchanov, Juri, Blechschmidt, Cristiane, Nielsen, Kirsten, Branding, Gordian, Arastéh, Keikawus, Tintelnot, Kathrin, Meintjes, Graeme, Boulware, David R., and Stocker, Hartmut

Subjects
Male, Antifungal Agents, AIDS-Related Opportunistic Infections, Anti-HIV Agents, Biopsy, Brain, HIV Infections, Meningitis, Cryptococcal, Article, Medication Adherence, Treatment Outcome, Immune Reconstitution Inflammatory Syndrome, Recurrence, Antiretroviral Therapy, Highly Active, Cryptococcus neoformans, Humans, Female, Fluconazole
Abstract

We report a case of a symptomatic relapse of HIV-related cryptococcal meningoencephalitis eight years after the first diagnosis on the background of immune reconstitution. The findings as well as the clinical course suggests a combination of smouldering localised infection and enhanced inflammatory reaction related to immune restoration due to antiretroviral therapy. A combination of antifungal and anti-inflammatory therapy resulted in clinical and radiological improvement. Our case challenges the concept that immune reconstitution inflammatory syndrome and microbiological relapse are dichotomous entities.

Published
2014

49. Prospective multicenter German study on pulmonary colonization with Scedosporium /Lomentospora species in cystic fibrosis: Epidemiology and new association factors

Author

Schwarz, Carsten, primary, Brandt, Claudia, additional, Antweiler, Elisabeth, additional, Krannich, Alexander, additional, Staab, Doris, additional, Schmitt-Grohé, Sabina, additional, Fischer, Rainald, additional, Hartl, Dominik, additional, Thronicke, Anja, additional, and Tintelnot, Kathrin, additional

Published
2017
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50. Identification and Characterization of VNI/VNII and Novel VNII/VNIV Hybrids and Impact of Hybridization on Virulence and Antifungal Susceptibility Within the C. neoformans/C. gattii Species Complex

Author

Aminnejad, Mojgan, primary, Cogliati, Massimo, additional, Duan, Shuyao, additional, Arabatzis, Michael, additional, Tintelnot, Kathrin, additional, Castañeda, Elizabeth, additional, Lazéra, Marcia, additional, Velegraki, Aristea, additional, Ellis, David, additional, Sorrell, Tania C., additional, and Meyer, Wieland, additional

Published
2016
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