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Addressing how strong UV radiation affects galaxy formation is central to understanding their evolution. The quenching of star formation via strong UV radiation (from starbursts or active galactic nuclei) has been proposed in various scenes to solve certain astrophysical problems. Around luminous sources, some evidence of decreased star formation has been found but is limited to a handful of individual cases. No direct, conclusive evidence on the actual role of strong UV radiation in quenching star formation has been found. Here, we present statistical evidence of decreased number density of faint (AB magnitude ≥ 24.75 mag) Ly α emitters (LAEs) around bright (AB magnitude < 24.75 mag) LAEs even when the radius goes up to 10 pMpc for z ≃ 5.7 LAEs. A similar trend is found for z ≃ 6.6 LAEs but only for faint LAEs within 1 pMpc radius from the bright LAEs. We use a large sample of 1077 (962) LAEs at z ≃ 5.7 (z ≃ 6.6) selected in total areas of 14 (21) deg2 with Subaru/Hyper Suprime-Cam narrow-band data, and thus, the result is of statistical significance for the first time at these high redshift ranges. A simple analytical calculation indicates that the radiation from the central LAE is not enough to suppress LAEs with AB mag ≥ 24.75 mag around them, suggesting additional physical mechanisms we are unaware of are at work. Our results clearly show that the environment is at work for the galaxy formation at z ∼ 6 in the Universe.

How does the environment affect active galactic nucleus (AGN) activity? We investigated this question in an extinction-free way, by selecting 1120 infrared galaxies in the $AKARI$ North Ecliptic Pole Wide field at redshift $z$ $\leq$ 1.2. A unique feature of the $AKARI$ satellite is its continuous 9-band infrared (IR) filter coverage, providing us with an unprecedentedly large sample of IR spectral energy distributions (SEDs) of galaxies. By taking advantage of this, for the first time, we explored the AGN activity derived from SED modelling as a function of redshift, luminosity, and environment. We quantified AGN activity in two ways: AGN contribution fraction (ratio of AGN luminosity to the total IR luminosity), and AGN number fraction (ratio of number of AGNs to the total galaxy sample). We found that galaxy environment (normalised local density) does not greatly affect either definitions of AGN activity of our IRG/LIRG samples (log ${\rm L}_{\rm TIR}$ $\leq$ 12). However, we found a different behavior for ULIRGs (log ${\rm L}_{\rm TIR}$ $>$ 12). At our highest redshift bin (0.7 $\lesssim$ z $\lesssim$ 1.2), AGN activity increases with denser environments, but at the intermediate redshift bin (0.3 $\lesssim$ z $\lesssim$ 0.7), the opposite is observed. These results may hint at a different physical mechanism for ULIRGs. The trends are not statistically significant (p $\geq$ 0.060 at the intermediate redshift bin, and p $\geq$ 0.139 at the highest redshift bin). Possible different behavior of ULIRGs is a key direction to explore further with future space missions (e.g., $JWST$, $Euclid$, $SPHEREx$)., Accepted for publication in MNRAS. A summary video is available at https://www.youtube.com/watch?v=7Y_a0kJkLI4&ab_channel=NthuCosmology

The search for extraterrestrial intelligence (SETI) has been conducted for nearly 60 years. A Dyson Sphere, a spherical structure that surrounds a star and transports its radiative energy outward as an energy source for an advanced civilisation, is one of the main targets of SETI. In this study, we discuss whether building a Dyson Sphere around a black hole is effective. We consider six energy sources: (i) the cosmic microwave background, (ii) the Hawking radiation, (iii) an accretion disk, (iv) Bondi accretion, (v) a corona, and (vi) relativistic jets. To develop future civilisations (for example, a Type II civilisation), $4\times10^{26}\,{\rm W}$($1\,{\rm L_{\odot}}$) is expected to be needed. Among (iii) to (vi), the largest luminosity can be collected from an accretion disk, reaching $10^{5}\,{\rm L_{\odot}}$, enough to maintain a Type II civilisation. Moreover, if a Dyson Sphere collects not only the electromagnetic radiation but also other types of energy (e.g., kinetic energy) from the jets, the total collected energy would be approximately 5 times larger. Considering the emission from a Dyson Sphere, our results show that the Dyson Sphere around a stellar-mass black hole in the Milky Way ($10\,\rm kpc$ away from us) is detectable in the ultraviolet$(\rm 10-400\,{\rm nm)}$, optical$(\rm 400-760\,{\rm nm)}$, near-infrared($\rm 760\,{\rm nm}-5\,{\rm \mu m}$), and mid-infrared($\rm 5-40\,{\rm \mu m}$) wavelengths via the waste heat radiation using current telescopes such as Galaxy Evolution Explorer Ultraviolet Sky Surveys. Performing model fitting to observed spectral energy distributions and measuring the variability of radial velocity may help us to identify these possible artificial structures., Comment: This paper has been accepted for publication in MNRAS

Modulation of presynaptic actin dynamics is fundamental to synaptic growth and functional plasticity; yet the underlying molecular and cellular mechanisms remain largely unknown. At Drosophila NMJs, the presynaptic Rac1-SCAR pathway mediates BMP-induced receptor macropinocytosis to inhibit BMP growth signaling. Here, we show that the Rho-type GEF Vav acts upstream of Rac1 to inhibit synaptic growth through macropinocytosis. We also present evidence that Vav-Rac1-SCAR signaling has additional roles in tetanus-induced synaptic plasticity. Presynaptic inactivation of Vav signaling pathway components, but not regulators of macropinocytosis, impairs post-tetanic potentiation (PTP) and enhances synaptic depression depending on external Ca2+ concentration. Interfering with the Vav-Rac1-SCAR pathway also impairs mobilization of reserve pool (RP) vesicles required for tetanus-induced synaptic plasticity. Finally, treatment with an F-actin–stabilizing drug completely restores RP mobilization and plasticity defects in Vav mutants. We propose that actin-regulatory Vav-Rac1-SCAR signaling independently regulates structural and functional presynaptic plasticity by driving macropinocytosis and RP mobilization, respectively.

To understand the cosmic accretion history of supermassive black holes, separating the radiation from active galactic nuclei (AGNs) and star-forming galaxies (SFGs) is critical. However, a reliable solution on photometrically recognising AGNs still remains unsolved. In this work, we present a novel AGN recognition method based on Deep Neural Network (Neural Net; NN). The main goals of this work are (i) to test if the AGN recognition problem in the North Ecliptic Pole Wide (NEPW) field could be solved by NN; (ii) to shows that NN exhibits an improvement in the performance compared with the traditional, standard spectral energy distribution (SED) fitting method in our testing samples; and (iii) to publicly release a reliable AGN/SFG catalogue to the astronomical community using the best available NEPW data, and propose a better method that helps future researchers plan an advanced NEPW database. Finally, according to our experimental result, the NN recognition accuracy is around 80.29% - 85.15%, with AGN completeness around 85.42% - 88.53% and SFG completeness around 81.17% - 85.09%., Comment: 12 pages, 12 figures

The Hubble constant ($H_{0}$) is a measurement to describe the expansion rate of the Universe in the current era. However, there is a $4.4\sigma$ discrepancy between the measurements from the early Universe and the late Universe. In this research, we propose a model-free and distance-free method to constrain $H_{0}$. Combining Friedman-Lema\^itre-Robertson-Walker cosmology with geometrical relation of the proper motion of extragalactic jets, the lower limit ($H_{\rm 0,min}$) of $H_{0}$ can be determined using only three cosmology-free observables: the redshifts of the host galaxies, as well as the approaching and receding angular velocities of radio jets. Using these, we propose to use the Kolmogorov-Smirnov test (K-S test) between cumulative distribution functions of $H_{\rm 0,min}$ to differentiate cosmology. We simulate 100, 200, and 500 extragalactic jets with 3 levels of accuracy of the proper motion ($\mu_{a}$ and $\mu_{r}$), at $10\%$, $5\%$, and $1\%$, corresponding to the accuracies of the current and future radio interferometers. We perform K-S tests between the simulated samples as theoretical distributions with different $H_{0}$ and power-law index of velocity distribution of jets and mock observational data. Our result suggests increasing sample sizes leads to tighter constraints on both power-law index and the Hubble constant at moderate accuracy (i.e., $10\%$ and $5\%$) while at $1\%$ accuracy, increasing sample sizes leads to tighter constraints on power-law index more. Improving accuracy results in better constraints in the Hubble constant compared with the power-law index in all cases but it alleviates the degeneracy., Comment: 13 pages, 14 figures, accepted for publication in MNRAS

Gamma-Ray Bursts (GRBs) can be a promising tracer of cosmic star-formation rate history (CSFRH). In order to reveal the CSFRH using GRBs, it is important to understand whether they are biased tracers or not. For this purpose, it is crucial to understand properties of GRB host galaxies, in comparison to field galaxies. In this work, we report ALMA far-infrared (FIR) observations of six $z\sim2$ IR-bright GRB host galaxies, which are selected for the brightness in IR. Among them, four host galaxies are detected for the first time in the rest-frame FIR. In addition to the ALMA data, we collected multi-wavelength data from previous studies for the six GRB host galaxies. Spectral energy distribution (SED) fitting analyses were performed with \texttt{CIGALE} to investigate physical properties of the host galaxies, and to test whether active galactic nucleus (AGN) and radio components are required or not. Our results indicate that the best-fit templates of five GRB host galaxies do not require an AGN component, suggesting the absence of AGNs. One GRB host galaxy, 080207, shows a very small AGN contribution. While derived stellar masses of the three host galaxies are mostly consistent with those in previous studies, interestingly the value of star-formation rates (SFRs) of all six GRB hosts are inconsistent with previous studies. Our results indicate the importance of rest-frame FIR observations to correctly estimate SFRs by covering thermal emission from cold dust heated by star formation., Comment: This paper has been accepted for publication in MNRAS

Fast radio bursts (FRBs) are astronomical transients with millisecond timescales occurring at cosmological distances. The observed time lag between different energies of each FRB is well described by the inverse-square law of the observed frequency, i.e., dispersion measure. Therefore, FRBs provide one of the ideal laboratories to test Einstein's weak equivalence principle (WEP): the hypothetical time lag between photons with different energies under a gravitational potential. If WEP is violated, such evidence should be exposed within the observational uncertainties of dispersion measures, unless the WEP violation also depends on the inverse-square of the observed frequency. In this work, we constrain the difference of gamma parameters ($\Delta\gamma$) between photons with different energies using the observational uncertainties of FRB dispersion measures, where $\Delta\gamma=0$ for Einstein's general relativity. Adopting the averaged 'Shapiro time delay' for cosmological sources, FRB 121002 at $z=1.6\pm0.3$ and FRB 180817.J1533+42 at $z=1.0\pm0.2$ place the most stringent constraints of $\log\Delta\gamma, Comment: Accepted for publication in Physical Review D. A summary video is available at https://youtu.be/Rt7tXN02wpQ

As recent advancements in physics and astronomy rapidly rewrite textbooks, there is a growing need in keeping abreast of the latest knowledge in these fields. Reading preprints is one of the effective ways to do this. By having journal clubs where people can read and discuss journals together, the benefits of reading journals become more prevalent. We present an investigative study of understanding the factors that affect the success of preprint journal clubs in astronomy, more commonly known as Astro-ph/Astro-Coffee (hereafter called AC). A survey was disseminated to understand how institutions from different countries implement AC. We interviewed 9 survey respondents and from their responses we identified four important factors that make AC successful: commitment (how the organizer and attendees participate in AC), environment (how conducive and comfortable AC is conducted), content (the discussed topics in AC and how they are presented), and objective (the main goal/s of conducting AC). We also present the format of our AC, an elective class which was evaluated during the Spring Semester 2020 (March 2020 - June 2020). Our evaluation with the attendees showed that enrollees (those who are enrolled and are required to present papers regularly) tend to be more committed in attending compared to audiences (those who are not enrolled and are not required to present papers regularly). In addition, participants tend to find papers outside their research field harder to read. Finally, we showed an improvement in the weekly number of papers read after attending AC of those who present papers regularly, and a high satisfaction rating of our AC. We summarize the areas of improvement in our AC implementation, and we encourage other institutions to evaluate their own AC in accordance with the four aforementioned factors to assess the effectiveness of their AC in reaching their goals., Accepted for publication in PRPER. A summary video is available at http://www.youtube.com/watch?v=fzy2I_xA_dU&ab_channel=NthuCosmology

A1689-zD1 is one of the most distant galaxies, discovered with the aid of gravitational lensing, providing us with an important opportunity to study galaxy formation in the very early universe. In this study, we report the detection of [C ii]158 μm and [O iii]88 μm emission lines of A1689-zD1 in the Atacama Large Millimeter/submillimeter Array (ALMA) Bands 6 and 8. We measure the redshift of this galaxy as z sys = 7.133 ± 0.005 based on the [C ii] and [O iii] emission lines, consistent with that adopted by Bakx et al. The observed L [O III]/L [C II] ratio is 2.09 ± 0.09, higher than that of most of the local galaxies, but consistent with other z ∼ 7 galaxies. The moderate spatial resolution of ALMA data provided us with a precious opportunity to investigate spatial variation of L [O III]/L [C II]. In contrast to the average value of 2.09, we find a much higher L [O III]/L [C II] of ∼7 at the center of the galaxy. This spatial variation of L [O III]/L [C II] was seldom reported for other high-z galaxies. It is also interesting that the peak of the ratio does not overlap with optical peaks. Possible physical reasons include a central active galactic nucleus, shock heating from merging, and a starburst. Our moderate spatial resolution data also reveal that in addition to the observed two clumps shown in previous Hubble Space Telescope images, there is a redshifted segment to the west of the northern optical clump. This structure is consistent with previous claims that A1689-zD1 is a merging galaxy, but with the northern redshifted part being some ejected material, or that the northern redshifted material stems from a third more highly obscured region of the galaxy.

Revealing the cosmic reionisation history is at the frontier of extragalactic astronomy. The power spectrum of the cosmic microwave background (CMB) polarisation can be used to constrain the reionisation history. Here we propose a CMB-independent method using fast radio bursts (FRBs) to directly measure the ionisation fraction of the intergalactic medium (IGM) as a function of redshift. FRBs are new astronomical transients with millisecond timescales. Their dispersion measure (DM$_{\rm IGM}$) is an indicator of the amount of ionised material in the IGM. Since the differential of DM$_{\rm IGM}$ against redshift is proportional to the ionisation fraction, our method allows us to directly measure the reionisation history without any assumption on its functional shape. As a proof of concept, we constructed mock non-repeating FRB sources to be detected with the Square Kilometre Array, assuming three different reionisation histories with the same optical depth of Thomson scattering. We considered three cases of redshift measurements: (A) spectroscopic redshift for all mock data, (B) spectroscopic redshift for 10% of mock data, and (C) redshift estimated from an empirical relation of FRBs between their time-integrated luminosity and rest-frame intrinsic duration. In all cases, the reionisation histories are consistently reconstructed from the mock FRB data using our method. Our results demonstrate the capability of future FRBs in constraining the reionisation history., Accepted for publication in MNRAS. A summary video is available at https://youtu.be/uis6h_cBnpE

Einstein's General Relativity (GR) is the basis of modern astronomy and astrophysics. Testing the validity of basic assumptions of GR is important. In this work, we test a possible violation of the Weak Equivalence Principle (WEP), i.e., there might be a time-lag between photons of different frequencies caused by the effect of gravitational fields if the speeds of photons are slightly different at different frequencies. We use Fast Radio Bursts (FRBs) , which are astronomical transients with millisecond timescales detected in the radio frequency range. Being at cosmological distances, accumulated time delay of FRBs can be caused by the plasma in between an FRB source and an observer, and by gravitational fields in the path of the signal. We segregate the delay due to dispersion and gravitational field using the post-Newtonian formalism (PPN) parameter $\Delta \gamma$, which defines the space-curvature due to gravity by a unit test mass. We did not detect any time-delay from FRBs but obtained tight constraints on the upper limit of $\Delta \gamma$. For FRB20181117C with $z = 1.83 \pm 0.28$ and $\nu_{obs}$ = $676.5\,{\rm MHz}$, the best possible constraint is obtained at log($\Delta \gamma$) = $-21.58 ^{+0.10}_{-0.12}$ and log($\Delta \gamma$/$r_{\rm E}$) = $-21.75 ^{+0.10}_{-0.14}$, respectively, where $r_{\rm E}$ is the energy ratio of two photons of the same FRB signal. This constraint is about one order of magnitude better than the previous constraint obtained with FRBs, and five orders tighter than any constraint obtained using other cosmological sources., Comment: Accepted for publication in Monthly Notices of the Royal Astronomical Society

The origins of fast radio bursts (FRBs), astronomical transients with millisecond timescales, remain unknown. One of the difficulties stems from the possibility that observed FRBs could be heterogeneous in origin; as some of them have been observed to repeat, and others have not. Due to limited observing periods and telescope sensitivities, some bursts may be misclassified as non-repeaters. Therefore, it is important to clearly distinguish FRBs into repeaters and non-repeaters, to better understand their origins. In this work, we classify repeaters and non-repeaters using unsupervised machine learning, without relying on expensive monitoring observations. We present a repeating FRB recognition method based on the Uniform Manifold Approximation and Projection (UMAP). The main goals of this work are to: (i) show that the unsupervised UMAP can classify repeating FRB population without any prior knowledge about their repetition, (ii) evaluate the assumption that non-repeating FRBs are contaminated by repeating FRBs, and (iii) recognise the FRB repeater candidates without monitoring observations and release a corresponding catalogue. We apply our method to the Canadian Hydrogen Intensity Mapping Experiment Fast Radio Burst (CHIME/FRB) database. We found that the unsupervised UMAP classification provides a repeating FRB completeness of 95 per cent and identifies 188 FRB repeater source candidates from 474 non-repeater sources. This work paves the way to a new classification of repeaters and non-repeaters based on a single epoch observation of FRBs., Comment: 10 pages, 9 figures, accepted for publication in MNRAS. For summary video, please see https://youtu.be/fWfvfFPDhcQ

Synaptic vesicle (SV) endocytosis is coupled to exocytosis to maintain SV pool size and thus neurotransmitter release. Intense stimulation induces activity-dependent bulk endocytosis (ADBE) to recapture large quantities of SV constituents in large endosomes from which SVs reform. How these consecutive processes are spatiotemporally coordinated remains unknown. Here, we show that Flower Ca2+channel-dependent phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) compartmentalization governs control of these processes inDrosophila. Strong stimuli trigger PI(4,5)P2microdomain formation at periactive zones. Upon exocytosis, Flower translocates from SVs to periactive zones, where it increases PI(4,5)P2levels via Ca2+influxes. Remarkably, PI(4,5)P2directly enhances Flower channel activity, thereby establishing a positive feedback loop for PI(4,5)P2microdomain compartmentalization. PI(4,5)P2microdomains drive ADBE and SV reformation from bulk endosomes. PI(4,5)P2further retrieves Flower to bulk endosomes, terminating endocytosis. We propose that the interplay between Flower and PI(4,5)P2is the crucial spatiotemporal cue that couples exocytosis to ADBE and subsequent SV reformation.

Fast radio bursts (FRBs) are mysterious extragalactic radio signals. Revealing their origin is one of the central foci in modern astronomy. Previous studies suggest that occurrence rates of non-repeating and repeating FRBs could be controlled by the cosmic stellar-mass density (CSMD) and star formation-rate density (CSFRD), respectively. The Square Kilometre Array (SKA) is one of the best future instruments to address this subject due to its high sensitivity and high-angular resolution. Here, we predict the number of FRBs to be detected with the SKA. In contrast to previous predictions, we estimate the detections of non-repeating and repeating FRBs separately, based on latest observational constraints on their physical properties including the spectral indices, FRB luminosity functions, and their redshift evolutions. We consider two cases of redshift evolution of FRB luminosity functions following either the CSMD or CSFRD. At $z\gtrsim2$, $z\gtrsim6$ and $z\gtrsim10$, non-repeating FRBs will be detected with the SKA at a rate of $\sim10^{4}$, $\sim10^{2}$, and $\sim10$ (sky$^{-1}$ day$^{-1}$), respectively, if their luminosity function follows the CSMD evolution. At $z\gtrsim1$, $z\gtrsim2$, and $z\gtrsim4$, sources of repeating FRBs will be detected at a rate of $\sim10^{3}$, $\sim10^{2}$, and $\lesssim10$ (sky$^{-1}$ day$^{-1}$), respectively, assuming that the redshift evolution of their luminosity function is scaled with the CSFRD. These numbers could change by about one order of magnitude depending on the assumptions on the CSMD and CSFRD. In all cases, abundant FRBs will be detected by the SKA, which will further constrain the luminosity functions and number density evolutions., Accepted for publication in MNRAS. A summary is available at https://www.youtube.com/watch?v=c-30UghzCO8

Observationally, it has been reported that the densest stellar system in the Universe does not exceed a maximum stellar surface density, $\Sigma^{\max}_{*}$ = $3\times10^5$M$_{\odot}$pc$^{-2}$, throughout a wide physical scale ranging from star cluster to galaxy. This suggests there exists a fundamental physics which regulates the star formation and stellar density. However, factors that determine this maximum limit are not clear. In this study, we show that $\Sigma^{\max}_{*}$ of galaxies is not a constant as previous work reported, but actually depends on the stellar mass. We select galaxy sample from the Sloan Digital Sky Survey Data Release 12 at $z=0.01-0.5$. In contrast to a constant maximum predicted by theoretical models, $\Sigma^{\max}_{*}$ strongly depends on stellar mass especially for less massive galaxies with $\sim10^{10}$M$_{\odot}$. We also found that a majority of high-$\Sigma_{*}$ galaxies show red colours and low star-formation rates. These galaxies probably reach the $\Sigma^{\max}_{*}$ as a consequence of the galaxy evolution from blue star forming to red quiescent by quenching star formation. One possible explanation of the stellar-mass dependency of $\Sigma^{\max}_{*}$ is a mass dependent efficiency of stellar feedback. The stellar feedback could be relatively more efficient in a shallower gravitational potential, which terminates star formation quickly before the stellar system reaches a high stellar density., Comment: 6 pages, 6 figures, accepted for publication in MNRAS. Summary of the paper can be found at https://www.youtube.com/watch?v=7OVnOmT25O0

Recommender systems have been widely used in many fields, but have been particularly common in the generation of user feedback. For Taiwanese employment websites, recommender systems match job seekers with employers but often fail to satisfy both the job seekers’ preferences and the prospective employers’ requirements. In the process, these websites often waste users’ time. To address this problem, this research proposes a hybrid-feedback recommender system specifically for job seekers in the context of Taiwan’s online employment scene. To identify the correlations between job searches and active job-seeking users, this research harness both implicit and explicit techniques that are based on user portfolios and a new data-mining technique called JSS-Tree. With the system, job seekers can spend less time and get better results than is currently possible on Taiwanese employment websites. Furthermore, through JSS-Tree, the recommender system generates substantially diverse recommendation results for job seekers, who thus have more choices than would normally be available and who can avoid wasting time while searching for desirable jobs on employment websites.

Fast radio bursts (FRBs) are mysterious radio bursts with a time scale of approximately milliseconds. Two populations of FRB, namely repeating and non-repeating FRBs, are observationally identified. However, the differences between these two and their origins are still cloaked in mystery. Here we show the time-integrated luminosity-duration ($L_{\nu}$-$w_{\rm int,rest}$) relations and luminosity functions (LFs) of repeating and non-repeating FRBs in the FRB Catalogue project. These two populations are obviously separated in the $L_{\nu}$-$w_{\rm int,rest}$ plane with distinct LFs, i.e., repeating FRBs have relatively fainter $L_{\nu}$ and longer $w_{\rm int,rest}$ with a much lower LF. In contrast with non-repeating FRBs, repeating FRBs do not show any clear correlation between $L_{\nu}$ and $w_{\rm int,rest}$. These results suggest essentially different physical origins of the two. The faint ends of the LFs of repeating and non-repeating FRBs are higher than volumetric occurrence rates of neutron-star mergers and accretion-induced collapse (AIC) of white dwarfs, and are consistent with those of soft gamma-ray repeaters (SGRs), type Ia supernovae, magnetars, and white-dwarf mergers. This indicates two possibilities: either (i) faint non-repeating FRBs originate in neutron-star mergers or AIC and are actually repeating during the lifetime of the progenitor, or (ii) faint non-repeating FRBs originate in any of SGRs, type Ia supernovae, magnetars, and white-dwarf mergers. The bright ends of LFs of repeating and non-repeating FRBs are lower than any candidates of progenitors, suggesting that bright FRBs are produced from a very small fraction of the progenitors regardless of the repetition. Otherwise, they might originate in unknown progenitors., Comment: Accepted by MNRAS. For a summary of the paper, please see below. https://youtu.be/Q0wK6gQzApc

Fast radio bursts (FRBs) are millisecond transients of unknown origin(s) occurring at cosmological distances. Here we, for the first time, show time-integrated-luminosity functions and volumetric occurrence rates of non-repeating and repeating FRBs against redshift. The time-integrated-luminosity functions of non-repeating FRBs do not show any significant redshift evolution. The volumetric occurrence rates are almost constant during the past $\sim$10 Gyr. The nearly-constant rate is consistent with a flat trend of cosmic stellar-mass density traced by old stellar populations. Our findings indicate that the occurrence rate of non-repeating FRBs follows the stellar-mass evolution of long-living objects with $\sim$Gyr time scales, favouring e.g. white dwarfs, neutron stars, and black holes, as likely progenitors of non-repeating FRBs. In contrast, the occurrence rates of repeating FRBs may increase towards higher redshifts in a similar way to the cosmic star formation-rate density or black hole accretion-rate density if the slope of their luminosity function does not evolve with redshift. Short-living objects with $\lesssim$ Myr time scales associated with young stellar populations (or their remnants, e.g., supernova remnants, young pulsars, and magnetars) or active galactic nuclei might be favoured as progenitor candidates of repeating FRBs., Comment: Accepted for publication in MNRAS. A video summary is available at https://youtu.be/8CpiJepkBeo The catalogue used in this work is available at http://www.phys.nthu.edu.tw/~tetsuya/

Investigating the Gunn-Peterson trough of high redshift quasars (QSOs) is a powerful way to reveal the cosmic reionization. As one of such attempts, we perform a series of analyses to examine the absorption lines observed with one of the highest redshift QSOs, PSO J006.1240+39.2219, which we previously discovered at z = 6.62. Using the Subaru telescope, we obtained medium-resolution spectrum with a total exposure time of 7.5 hours. We calculate the Ly$\alpha$ transmission in different redshift bins to determine the near zone radius and the optical depth at 5.6$$5.8). All three analyses based on this QSO show increasingly neutral hydrogen towards higher redshifts, adding precious measurements up to z$\sim$6.5., Comment: 11 pages, 10 figures, 5 tables, Accepted for Publication in ApJ

Oximes have been identified as reusable templates for the synthesis of ureas and carbamates by an in situ generation of carbamoyl oximes under metal-free conditions. The recovered oxime has been utilised for three trials in the synthesis of urea derivatives without any loss in the yield and efficiency. In addition, this template approach could override the usage of hazardous and less stable isocyanates as substrates.

We present the analysis of a new near-infrared (NIR) spectrum of a recently discovered $z=6.621$ quasar PSO J006+39 in an attempt to explore the early growth of supermassive black holes (SMBHs). This NIR (rest-frame ultraviolet, UV) spectrum shows blue continuum slope and rich metal emission lines in addition to Ly$\alpha$ line. We utilize the MgII line width and the rest frame luminosity $L_\text{3000\AA}$ to find the mass of SMBH ($M_\text{BH}$) to be $\sim 10^8 M_\odot$, making this one of the lowest mass quasars at high redshift. The power-law slope index ($\alpha_\lambda$) of the continuum emission is $-2.94\pm0.03$, significantly bluer than the slope of $\alpha_\lambda=-7/3$ predicted from standard thin disc models. We fit the spectral energy distribution (SED) using a model which can fit local SMBHs, which includes warm and hot Comptonisation powered by the accretion flow as well as an outer standard disc. The result shows that the very blue slope is probably produced by a small radial ($\sim230$ gravitational radius, $R_\text{g}$) extent of the standard accretion disc. All plausible SED models require that the source is super-Eddington ($L_\text{bol}/L_\text{Edd} \gtrsim 9$), so the apparently small disc may simply be the inner funnel of a puffed up flow, and clearly the SMBH in this quasar is in a rapid growth phase. We also utilize the rest-frame UV emission lines to probe the chemical abundance in the broad line region (BLR) of this quasar. We find that this quasar has super solar metallicity through photoionization model calculations., Comment: Accepted for publication in Monthly Notices of the Royal Astronomical Society, 12 pages including 12 figures and 4 tables

Autism spectrum disorder (ASD) is a neurodevelopmental disorder, characterized by social interaction impairment, stereotypical/repetitive behaviors and emotional deregulation. The endocannabinoid (eCB) system plays a crucial role in modulating the behavioral traits that are typically core symptoms of ASD. The major molecular mechanisms underlying eCB-dependent long-term depression (eCB-LTD) are mediated by group 1 metabotropic glutamate receptor (mGluR)-induced removal of postsynaptic α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs). Recently, modulation of anandamide (AEA), one of the main endocannabinoids in the brain, has been reported to alter social behaviors in genetic models of ASD. On this basis, we investigated the effects of treatment and the synaptic mechanism underlying AEA-mediated signaling in prenatal exposure to valproic acid (VPA) in rats. We found that the social deficits, repetitive behaviors and abnormal emotion-related behaviors in VPA-exposed offspring were improved after treatment with an inhibitor of AEA degrading enzyme, URB597. Using an integrative approach combing electrophysiological and cellular mechanisms, the results showed that the impaired eCB-LTD, abnormal mGluR-mediated LTD (mGluR-LTD) and decreased removal of AMPAR subunits GluA1 and GluA2 were reversed by URB597 in the prefrontal cortex (PFC) of VPA-exposed offspring. Taken together, these results provide the first evidence that rescue of the ASD-like phenotype by URB597 is mediated by enhancing the mechanism of removal of AMPAR subunits GluA1/2 underlying AEA signaling in the PFC in a VPA-induced model of ASD.

I2–TBHP-catalyzed oxidative cross coupling of N-sulfonyl hydrazones with isocyanides has been realized for the synthesis of 5-aminopyrazoles through formal [4 + 1] annulation via in situ azoalkene formation. Notable features are the metal/alkyne-free strategy, C–C and C–N bond formation, atom economy, catalytic I2, broad functional group tolerance, good reaction yields, shorter time, and also applicability to one-pot methodology.

The palladium-catalyzed reaction of acetyl oximes with isocyanides was developed for the synthesis of 2H-pyrrol-2-imines. The key steps were (i) generation of an enamido-palladium(II) species, (ii) migratory double-isocyanide insertion, and (iii) cyclization. The scope of the synthesis of some 2H-pyrrol-2-imines was extended to the synthesis 1H-pyrrole-2,3-dione/1H-benzo[g]indole-2,3-dione derivatives via acid hydrolysis in a sequential one-pot manner.

An environmentally benign oxidative cross-coupling of a variety of N-sulfonylhydrazones with isocyanides through conjugate (C—C bond) and zwitterionic (C—N bond) bond formation is presented.

I2-TBHP-catalyzed oxidative cross coupling of N-sulfonyl hydrazones with isocyanides has been realized for the synthesis of 5-aminopyrazoles through formal [4 + 1] annulation via in situ azoalkene formation. Notable features are the metal/alkyne-free strategy, C-C and C-N bond formation, atom economy, catalytic I2, broad functional group tolerance, good reaction yields, shorter time, and also applicability to one-pot methodology.

A facile Suzuki type cross-coupling reaction of alkenylborane with 2-bromo- N , N -dimethylacetamide in the presence of a catalytic amount of tricyclohexylphosphine as the ligand has been demonstrated to be a convenient way for the synthesis of ( E )-β,γ-unsaturated amides.

A Suzuki-type cross-coupling of aryldioxaborolane with 2-bromo-N,N-dimethylacetamide in the presence of a catalytic amount of tricyclohexylphosphine as the ligand and hydroquinone as the free-radical scavenger has been demonstrated as a convenient and simple way for the synthesis of α-arylacetamide.

Globular clusters (GCs) are emerging as a new class of gamma-ray emitters, thanks to the data obtained from the Fermi Gamma-ray Space Telescope. By now, eight GCs are known to emit gamma-rays at energies >100~MeV. Based on the stellar encounter rate of the GCs, we identify potential gamma-ray emitting GCs out of all known GCs that have not been studied in details before. In this paper, we report the discovery of a number of new gamma-ray GCs: Liller 1, NGC 6624, and NGC 6752, and evidence for gamma-ray emission from M80, NGC 6139, and NGC 6541, in which gamma-rays were found within the GC tidal radius. With one of the highest metallicity among all GCs in the Milky Way, the gamma-ray luminosity of Liller 1 is found to be the highest of all known gamma-ray GCs. In addition, we confirm a previous report of significant gamma-ray emitting region next to NGC 6441. We briefly discuss the observed offset of gamma-rays from some GC cores. The increasing number of known gamma-ray GCs at distances out to ~10 kpc is important for us to understand the gamma-ray emitting mechanism and provides an alternative probe to the underlying millisecond pulsar populations of the GCs., 22 pages, 7 figures, 2 tables; ApJ, in press